Result of FASTA (omim) for
pFN21AE3195
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3195, 458 aa
1>>>pF1KE3195 458 - 458 aa - 458 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.9481+/-0.000368; mu= 12.2390+/- 0.023
mean_var=141.9773+/-28.807, 0's: 0 Z-trim(118.9): 61 B-trim: 2647 in 2/52
Lambda= 0.107638
statistics sampled from 32254 (32317) to 32254 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.718), E-opt: 0.2 (0.379), width: 16
Scan time: 9.960
The best scores are: opt bits E(85289)
NP_892023 (OMIM: 139312,615073) guanine nucleotide ( 458) 3081 489.8 6.2e-138
NP_001248372 (OMIM: 139312,615073) guanine nucleot ( 381) 2318 371.3 2.5e-102
NP_001135811 (OMIM: 139312,615073) guanine nucleot ( 381) 2318 371.3 2.5e-102
XP_016883303 (OMIM: 102200,103580,139320,166350,17 (1022) 2022 325.7 3.6e-88
XP_016883302 (OMIM: 102200,103580,139320,166350,17 (1023) 2010 323.8 1.3e-87
NP_001070957 (OMIM: 102200,103580,139320,166350,17 ( 379) 1975 318.0 2.7e-86
NP_536351 (OMIM: 102200,103580,139320,166350,17480 ( 380) 1963 316.2 9.9e-86
XP_016883304 (OMIM: 102200,103580,139320,166350,17 ( 347) 1897 305.9 1.1e-82
XP_016883308 (OMIM: 102200,103580,139320,166350,17 ( 320) 1818 293.6 5.2e-79
XP_016883306 (OMIM: 102200,103580,139320,166350,17 ( 320) 1818 293.6 5.2e-79
XP_016883307 (OMIM: 102200,103580,139320,166350,17 ( 320) 1818 293.6 5.2e-79
NP_001070956 (OMIM: 102200,103580,139320,166350,17 ( 395) 1778 287.4 4.5e-77
NP_000507 (OMIM: 102200,103580,139320,166350,17480 ( 394) 1777 287.3 5.1e-77
XP_016883301 (OMIM: 102200,103580,139320,166350,17 (1038) 1763 285.5 4.7e-76
NP_536350 (OMIM: 102200,103580,139320,166350,17480 (1037) 1762 285.3 5.2e-76
XP_016883309 (OMIM: 102200,103580,139320,166350,17 ( 320) 1749 282.9 8.8e-76
XP_016883305 (OMIM: 102200,103580,139320,166350,17 ( 320) 1749 282.9 8.8e-76
NP_001296769 (OMIM: 102200,103580,139320,166350,17 ( 335) 1749 282.9 9.1e-76
NP_001296790 (OMIM: 102200,103580,139320,166350,17 ( 335) 1749 282.9 9.1e-76
XP_006722387 (OMIM: 139312,615073) PREDICTED: guan ( 240) 1603 260.1 4.7e-69
NP_001248373 (OMIM: 139312,615073) guanine nucleot ( 174) 1187 195.4 1e-49
NP_620073 (OMIM: 139311,615473) guanine nucleotide ( 354) 843 142.2 2.1e-33
NP_002059 (OMIM: 139314) guanine nucleotide-bindin ( 374) 834 140.8 5.9e-33
NP_002060 (OMIM: 139310) guanine nucleotide-bindin ( 354) 828 139.9 1.1e-32
NP_066268 (OMIM: 139311,615473) guanine nucleotide ( 354) 826 139.6 1.3e-32
NP_002063 (OMIM: 163000,185300,600998) guanine nuc ( 359) 822 139.0 2.1e-32
NP_005263 (OMIM: 139340,613856) guanine nucleotide ( 354) 816 138.0 3.9e-32
XP_011539566 (OMIM: 139340,613856) PREDICTED: guan ( 354) 816 138.0 3.9e-32
NP_001095856 (OMIM: 139395) guanine nucleotide-bin ( 354) 812 137.4 6e-32
NP_006487 (OMIM: 139370,602483) guanine nucleotide ( 354) 812 137.4 6e-32
NP_002061 (OMIM: 139360,192605) guanine nucleotide ( 355) 806 136.5 1.1e-31
XP_011514426 (OMIM: 139395) PREDICTED: guanine nuc ( 297) 804 136.1 1.2e-31
NP_653082 (OMIM: 139330,610444,616389) guanine nuc ( 350) 802 135.8 1.7e-31
NP_000163 (OMIM: 139330,610444,616389) guanine nuc ( 350) 802 135.8 1.7e-31
NP_002058 (OMIM: 139313) guanine nucleotide-bindin ( 359) 801 135.7 2e-31
NP_004288 (OMIM: 604397) guanine nucleotide-bindin ( 355) 783 132.9 1.4e-30
NP_002064 (OMIM: 139160) guanine nucleotide-bindin ( 355) 773 131.3 4e-30
NP_001159897 (OMIM: 139360,192605) guanine nucleot ( 318) 754 128.4 2.9e-29
NP_001269549 (OMIM: 139360,192605) guanine nucleot ( 339) 754 128.4 3e-29
NP_001269548 (OMIM: 139360,192605) guanine nucleot ( 339) 754 128.4 3e-29
NP_031379 (OMIM: 604394) guanine nucleotide-bindin ( 381) 712 121.9 3e-27
XP_011521305 (OMIM: 139311,615473) PREDICTED: guan ( 312) 699 119.8 1e-26
NP_001243343 (OMIM: 139310) guanine nucleotide-bin ( 302) 694 119.0 1.8e-26
NP_006563 (OMIM: 604406) guanine nucleotide-bindin ( 377) 685 117.7 5.4e-26
NP_001269546 (OMIM: 139360,192605) guanine nucleot ( 303) 675 116.1 1.4e-25
XP_016870117 (OMIM: 163000,185300,600998) PREDICTE ( 301) 658 113.4 8.4e-25
XP_016870830 (OMIM: 604397) PREDICTED: guanine nuc ( 301) 634 109.7 1.1e-23
NP_001269547 (OMIM: 139360,192605) guanine nucleot ( 274) 617 107.0 6.5e-23
XP_016884275 (OMIM: 139160) PREDICTED: guanine nuc ( 307) 608 105.7 1.9e-22
XP_011517526 (OMIM: 604397) PREDICTED: guanine nuc ( 237) 571 99.8 8.2e-21
>>NP_892023 (OMIM: 139312,615073) guanine nucleotide-bin (458 aa)
initn: 3081 init1: 3081 opt: 3081 Z-score: 2597.3 bits: 489.8 E(85289): 6.2e-138
Smith-Waterman score: 3081; 100.0% identity (100.0% similar) in 458 aa overlap (1-458:1-458)
10 20 30 40 50 60
pF1KE3 MGLCYSLRPLLFGGPGDDPCAASEPPVEDAQPAPAPALAPVRAAARDTARTLLPRGGEGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_892 MGLCYSLRPLLFGGPGDDPCAASEPPVEDAQPAPAPALAPVRAAARDTARTLLPRGGEGS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 PACARPKADKPKEKRQRTEQLSAEEREAAKEREAVKEARKVSRGIDRMLRDQKRDLQQTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_892 PACARPKADKPKEKRQRTEQLSAEEREAAKEREAVKEARKVSRGIDRMLRDQKRDLQQTH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 RLLLLGAGESGKSTIVKQMRILHVNGFNPEEKKQKILDIRKNVKDAIVTIVSAMSTIIPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_892 RLLLLGAGESGKSTIVKQMRILHVNGFNPEEKKQKILDIRKNVKDAIVTIVSAMSTIIPP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 VPLANPENQFRSDYIKSIAPITDFEYSQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_892 VPLANPENQFRSDYIKSIAPITDFEYSQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 YFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_892 YFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 CFNDVTAIIYVAACSSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_892 CFNDVTAIIYVAACSSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 LAEKVLAGKSKIEDYFPEYANYTVPEDATPDAGEDPKVTRAKFFIRDLFLRISTATGDGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_892 LAEKVLAGKSKIEDYFPEYANYTVPEDATPDAGEDPKVTRAKFFIRDLFLRISTATGDGK
370 380 390 400 410 420
430 440 450
pF1KE3 HYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLKQYELL
::::::::::::::::::::::::::::::::::::::
NP_892 HYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLKQYELL
430 440 450
>>NP_001248372 (OMIM: 139312,615073) guanine nucleotide- (381 aa)
initn: 2318 init1: 2318 opt: 2318 Z-score: 1958.0 bits: 371.3 E(85289): 2.5e-102
Smith-Waterman score: 2318; 95.0% identity (98.1% similar) in 363 aa overlap (96-458:19-381)
70 80 90 100 110 120
pF1KE3 PKADKPKEKRQRTEQLSAEEREAAKEREAVKEARKVSRGIDRMLRDQKRDLQQTHRLLLL
:: :.... :...:. .. . :::::::
NP_001 MGCLGGNSKTTEDQGVDEKERREANKKIEKQLQKERLAYKATHRLLLL
10 20 30 40
130 140 150 160 170 180
pF1KE3 GAGESGKSTIVKQMRILHVNGFNPEEKKQKILDIRKNVKDAIVTIVSAMSTIIPPVPLAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAGESGKSTIVKQMRILHVNGFNPEEKKQKILDIRKNVKDAIVTIVSAMSTIIPPVPLAN
50 60 70 80 90 100
190 200 210 220 230 240
pF1KE3 PENQFRSDYIKSIAPITDFEYSQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQYFLER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PENQFRSDYIKSIAPITDFEYSQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQYFLER
110 120 130 140 150 160
250 260 270 280 290 300
pF1KE3 IDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDV
170 180 190 200 210 220
310 320 330 340 350 360
pF1KE3 TAIIYVAACSSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAIIYVAACSSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKV
230 240 250 260 270 280
370 380 390 400 410 420
pF1KE3 LAGKSKIEDYFPEYANYTVPEDATPDAGEDPKVTRAKFFIRDLFLRISTATGDGKHYCYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAGKSKIEDYFPEYANYTVPEDATPDAGEDPKVTRAKFFIRDLFLRISTATGDGKHYCYP
290 300 310 320 330 340
430 440 450
pF1KE3 HFTCAVDTENIRRVFNDCRDIIQRMHLKQYELL
:::::::::::::::::::::::::::::::::
NP_001 HFTCAVDTENIRRVFNDCRDIIQRMHLKQYELL
350 360 370 380
>>NP_001135811 (OMIM: 139312,615073) guanine nucleotide- (381 aa)
initn: 2318 init1: 2318 opt: 2318 Z-score: 1958.0 bits: 371.3 E(85289): 2.5e-102
Smith-Waterman score: 2318; 95.0% identity (98.1% similar) in 363 aa overlap (96-458:19-381)
70 80 90 100 110 120
pF1KE3 PKADKPKEKRQRTEQLSAEEREAAKEREAVKEARKVSRGIDRMLRDQKRDLQQTHRLLLL
:: :.... :...:. .. . :::::::
NP_001 MGCLGGNSKTTEDQGVDEKERREANKKIEKQLQKERLAYKATHRLLLL
10 20 30 40
130 140 150 160 170 180
pF1KE3 GAGESGKSTIVKQMRILHVNGFNPEEKKQKILDIRKNVKDAIVTIVSAMSTIIPPVPLAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAGESGKSTIVKQMRILHVNGFNPEEKKQKILDIRKNVKDAIVTIVSAMSTIIPPVPLAN
50 60 70 80 90 100
190 200 210 220 230 240
pF1KE3 PENQFRSDYIKSIAPITDFEYSQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQYFLER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PENQFRSDYIKSIAPITDFEYSQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQYFLER
110 120 130 140 150 160
250 260 270 280 290 300
pF1KE3 IDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDV
170 180 190 200 210 220
310 320 330 340 350 360
pF1KE3 TAIIYVAACSSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAIIYVAACSSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKV
230 240 250 260 270 280
370 380 390 400 410 420
pF1KE3 LAGKSKIEDYFPEYANYTVPEDATPDAGEDPKVTRAKFFIRDLFLRISTATGDGKHYCYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAGKSKIEDYFPEYANYTVPEDATPDAGEDPKVTRAKFFIRDLFLRISTATGDGKHYCYP
290 300 310 320 330 340
430 440 450
pF1KE3 HFTCAVDTENIRRVFNDCRDIIQRMHLKQYELL
:::::::::::::::::::::::::::::::::
NP_001 HFTCAVDTENIRRVFNDCRDIIQRMHLKQYELL
350 360 370 380
>>XP_016883303 (OMIM: 102200,103580,139320,166350,174800 (1022 aa)
initn: 2062 init1: 1997 opt: 2022 Z-score: 1703.8 bits: 325.7 E(85289): 3.6e-88
Smith-Waterman score: 2022; 71.1% identity (86.7% similar) in 422 aa overlap (42-458:601-1022)
20 30 40 50 60
pF1KE3 FGGPGDDPCAASEPPVEDAQPAPAPALAPVRAAARDTARTLLPR--GGE-GSPACARPKA
: :. :..: . :: : .:::
XP_016 SSDDDSSGDESDDGTSGCLRWFQHRRNRRRRKPQRNLLRNFLVQAFGGCFGRSESPQPKA
580 590 600 610 620 630
70 80 90 100 110 120
pF1KE3 DKP-KEKRQRTEQLSAEEREAAKEREAVKEA-RKVSRGIDRMLRDQKRDLQQTHRLLLLG
.. : :. . . :. : :..: :.: .: :. ::..:.:.: . ::::::::
XP_016 SRSLKVKKVPLAEKRRQMRKEALEKRAQKRAEKKRSKLIDKQLQDEKMGYMCTHRLLLLG
640 650 660 670 680 690
130 140 150 160 170 180
pF1KE3 AGESGKSTIVKQMRILHVNGFNPEEKKQKILDIRKNVKDAIVTIVSAMSTIIPPVPLANP
:::::::::::::::::::::: .:: :. ::..:.:.:: :::.:::...::: ::::
XP_016 AGESGKSTIVKQMRILHVNGFNGDEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANP
700 710 720 730 740 750
190 200 210 220 230 240
pF1KE3 ENQFRSDYIKSIAPITDFEYSQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQYFLERI
::::: ::: :. . ::.. ::..:.: ::.::::.::.::::::::::::::::..:
XP_016 ENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKI
760 770 780 790 800 810
250 260 270 280 290 300
pF1KE3 DSVSLVDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDVT
: .. .::.:.:::::::::::::::::.:::::::::::::::::::::::::::::::
XP_016 DVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVT
820 830 840 850 860 870
310 320 330 340 350 360
pF1KE3 AIIYVAACSSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKVL
:::.:.: :::::::::::.::::.:.:.::.::::::::::::.::::::::.::::::
XP_016 AIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVL
880 890 900 910 920 930
370 380 390 400 410 420
pF1KE3 AGKSKIEDYFPEYANYTVPEDATPDAGEDPKVTRAKFFIRDLFLRISTATGDGKHYCYPH
::::::::::::.: ::.::::::. ::::.:::::.:::: :::::::.:::.::::::
XP_016 AGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPH
940 950 960 970 980 990
430 440 450
pF1KE3 FTCAVDTENIRRVFNDCRDIIQRMHLKQYELL
::::::::::::::::::::::::::.:::::
XP_016 FTCAVDTENIRRVFNDCRDIIQRMHLRQYELL
1000 1010 1020
>>XP_016883302 (OMIM: 102200,103580,139320,166350,174800 (1023 aa)
initn: 1803 init1: 1749 opt: 2010 Z-score: 1693.8 bits: 323.8 E(85289): 1.3e-87
Smith-Waterman score: 2010; 70.9% identity (86.5% similar) in 423 aa overlap (42-458:601-1023)
20 30 40 50 60
pF1KE3 FGGPGDDPCAASEPPVEDAQPAPAPALAPVRAAARDTARTLLPR--GGE-GSPACARPKA
: :. :..: . :: : .:::
XP_016 SSDDDSSGDESDDGTSGCLRWFQHRRNRRRRKPQRNLLRNFLVQAFGGCFGRSESPQPKA
580 590 600 610 620 630
70 80 90 100 110 120
pF1KE3 DKP-KEKRQRTEQLSAEEREAAKEREAVKEA-RKVSRGIDRMLRDQKRDLQQTHRLLLLG
.. : :. . . :. : :..: :.: .: :. ::..:.:.: . ::::::::
XP_016 SRSLKVKKVPLAEKRRQMRKEALEKRAQKRAEKKRSKLIDKQLQDEKMGYMCTHRLLLLG
640 650 660 670 680 690
130 140 150 160 170 180
pF1KE3 AGESGKSTIVKQMRILHVNGFNPE-EKKQKILDIRKNVKDAIVTIVSAMSTIIPPVPLAN
:::::::::::::::::::::: . :: :. ::..:.:.:: :::.:::...::: :::
XP_016 AGESGKSTIVKQMRILHVNGFNGDSEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELAN
700 710 720 730 740 750
190 200 210 220 230 240
pF1KE3 PENQFRSDYIKSIAPITDFEYSQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQYFLER
:::::: ::: :. . ::.. ::..:.: ::.::::.::.::::::::::::::::..
XP_016 PENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDK
760 770 780 790 800 810
250 260 270 280 290 300
pF1KE3 IDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQCFNDV
:: .. .::.:.:::::::::::::::::.::::::::::::::::::::::::::::::
XP_016 IDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDV
820 830 840 850 860 870
310 320 330 340 350 360
pF1KE3 TAIIYVAACSSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDMLAEKV
::::.:.: :::::::::::.::::.:.:.::.::::::::::::.::::::::.:::::
XP_016 TAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKV
880 890 900 910 920 930
370 380 390 400 410 420
pF1KE3 LAGKSKIEDYFPEYANYTVPEDATPDAGEDPKVTRAKFFIRDLFLRISTATGDGKHYCYP
:::::::::::::.: ::.::::::. ::::.:::::.:::: :::::::.:::.:::::
XP_016 LAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYP
940 950 960 970 980 990
430 440 450
pF1KE3 HFTCAVDTENIRRVFNDCRDIIQRMHLKQYELL
:::::::::::::::::::::::::::.:::::
XP_016 HFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL
1000 1010 1020
>>NP_001070957 (OMIM: 102200,103580,139320,166350,174800 (379 aa)
initn: 1939 init1: 1939 opt: 1975 Z-score: 1670.2 bits: 318.0 E(85289): 2.7e-86
Smith-Waterman score: 1975; 76.4% identity (92.1% similar) in 368 aa overlap (91-458:12-379)
70 80 90 100 110 120
pF1KE3 PACARPKADKPKEKRQRTEQLSAEEREAAKEREAVKEARKVSRGIDRMLRDQKRDLQQTH
.:. : :.... :...:. .:. . ::
NP_001 MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATH
10 20 30 40
130 140 150 160 170 180
pF1KE3 RLLLLGAGESGKSTIVKQMRILHVNGFNPEEKKQKILDIRKNVKDAIVTIVSAMSTIIPP
:::::::::::::::::::::::::::: .:: :. ::..:.:.:: :::.:::...::
NP_001 RLLLLGAGESGKSTIVKQMRILHVNGFNGDEKATKVQDIKNNLKEAIETIVAAMSNLVPP
50 60 70 80 90 100
190 200 210 220 230 240
pF1KE3 VPLANPENQFRSDYIKSIAPITDFEYSQEFFDHVKKLWDDEGVKACFERSNEYQLIDCAQ
: ::::::::: ::: :. . ::.. ::..:.: ::.::::.::.:::::::::::::
NP_001 VELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQ
110 120 130 140 150 160
250 260 270 280 290 300
pF1KE3 YFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWIQ
:::..:: .. .::.:.:::::::::::::::::.:::::::::::::::::::::::::
NP_001 YFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQ
170 180 190 200 210 220
310 320 330 340 350 360
pF1KE3 CFNDVTAIIYVAACSSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQDM
:::::::::.:.: :::::::::::.::::.:.:.::.::::::::::::.::::::::.
NP_001 CFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDL
230 240 250 260 270 280
370 380 390 400 410 420
pF1KE3 LAEKVLAGKSKIEDYFPEYANYTVPEDATPDAGEDPKVTRAKFFIRDLFLRISTATGDGK
::::::::::::::::::.: ::.::::::. ::::.:::::.:::: :::::::.:::.
NP_001 LAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDGR
290 300 310 320 330 340
430 440 450
pF1KE3 HYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLKQYELL
::::::::::::::::::::::::::::::::.:::::
NP_001 HYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL
350 360 370
>>NP_536351 (OMIM: 102200,103580,139320,166350,174800,21 (380 aa)
initn: 1749 init1: 1749 opt: 1963 Z-score: 1660.1 bits: 316.2 E(85289): 9.9e-86
Smith-Waterman score: 1963; 76.2% identity (91.9% similar) in 369 aa overlap (91-458:12-380)
70 80 90 100 110 120
pF1KE3 PACARPKADKPKEKRQRTEQLSAEEREAAKEREAVKEARKVSRGIDRMLRDQKRDLQQTH
.:. : :.... :...:. .:. . ::
NP_536 MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATH
10 20 30 40
130 140 150 160 170
pF1KE3 RLLLLGAGESGKSTIVKQMRILHVNGFNPE-EKKQKILDIRKNVKDAIVTIVSAMSTIIP
:::::::::::::::::::::::::::: . :: :. ::..:.:.:: :::.:::...:
NP_536 RLLLLGAGESGKSTIVKQMRILHVNGFNGDSEKATKVQDIKNNLKEAIETIVAAMSNLVP
50 60 70 80 90 100
180 190 200 210 220 230
pF1KE3 PVPLANPENQFRSDYIKSIAPITDFEYSQEFFDHVKKLWDDEGVKACFERSNEYQLIDCA
:: ::::::::: ::: :. . ::.. ::..:.: ::.::::.::.::::::::::::
NP_536 PVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCA
110 120 130 140 150 160
240 250 260 270 280 290
pF1KE3 QYFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDVGGQRDERRKWI
::::..:: .. .::.:.:::::::::::::::::.::::::::::::::::::::::::
NP_536 QYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWI
170 180 190 200 210 220
300 310 320 330 340 350
pF1KE3 QCFNDVTAIIYVAACSSYNMVIREDNNTNRLRESLDLFESIWNNRWLRTISIILFLNKQD
::::::::::.:.: :::::::::::.::::.:.:.::.::::::::::::.::::::::
NP_536 QCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQD
230 240 250 260 270 280
360 370 380 390 400 410
pF1KE3 MLAEKVLAGKSKIEDYFPEYANYTVPEDATPDAGEDPKVTRAKFFIRDLFLRISTATGDG
.::::::::::::::::::.: ::.::::::. ::::.:::::.:::: :::::::.:::
NP_536 LLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGDG
290 300 310 320 330 340
420 430 440 450
pF1KE3 KHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLKQYELL
.::::::::::::::::::::::::::::::::.:::::
NP_536 RHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL
350 360 370 380
>>XP_016883304 (OMIM: 102200,103580,139320,166350,174800 (347 aa)
initn: 1897 init1: 1897 opt: 1897 Z-score: 1605.2 bits: 305.9 E(85289): 1.1e-82
Smith-Waterman score: 1897; 80.5% identity (94.0% similar) in 333 aa overlap (126-458:15-347)
100 110 120 130 140 150
pF1KE3 KEARKVSRGIDRMLRDQKRDLQQTHRLLLLGAGESGKSTIVKQMRILHVNGFNPEEKKQK
::::::::::::::::::::::: .:: :
XP_016 MEDAVQILLVFMDSGAGESGKSTIVKQMRILHVNGFNGDEKATK
10 20 30 40
160 170 180 190 200 210
pF1KE3 ILDIRKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSIAPITDFEYSQEFFDHVK
. ::..:.:.:: :::.:::...::: ::::::::: ::: :. . ::.. ::..:.:
XP_016 VQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAK
50 60 70 80 90 100
220 230 240 250 260 270
pF1KE3 KLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETR
::.::::.::.::::::::::::::::..:: .. .::.:.:::::::::::::::::.
XP_016 ALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETK
110 120 130 140 150 160
280 290 300 310 320 330
pF1KE3 FQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTNRLRESLD
::::::::::::::::::::::::::::::::::.:.: :::::::::::.::::.:.:.
XP_016 FQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALN
170 180 190 200 210 220
340 350 360 370 380 390
pF1KE3 LFESIWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDATPDAGED
::.::::::::::::.::::::::.::::::::::::::::::.: ::.::::::. :::
XP_016 LFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGED
230 240 250 260 270 280
400 410 420 430 440 450
pF1KE3 PKVTRAKFFIRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLKQY
:.:::::.:::: :::::::.:::.::::::::::::::::::::::::::::::::.::
XP_016 PRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQY
290 300 310 320 330 340
pF1KE3 ELL
:::
XP_016 ELL
>>XP_016883308 (OMIM: 102200,103580,139320,166350,174800 (320 aa)
initn: 1818 init1: 1818 opt: 1818 Z-score: 1539.4 bits: 293.6 E(85289): 5.2e-79
Smith-Waterman score: 1818; 79.7% identity (93.8% similar) in 320 aa overlap (139-458:1-320)
110 120 130 140 150 160
pF1KE3 LRDQKRDLQQTHRLLLLGAGESGKSTIVKQMRILHVNGFNPEEKKQKILDIRKNVKDAIV
:::::::::: .:: :. ::..:.:.::
XP_016 MRILHVNGFNGDEKATKVQDIKNNLKEAIE
10 20 30
170 180 190 200 210 220
pF1KE3 TIVSAMSTIIPPVPLANPENQFRSDYIKSIAPITDFEYSQEFFDHVKKLWDDEGVKACFE
:::.:::...::: ::::::::: ::: :. . ::.. ::..:.: ::.::::.::.:
XP_016 TIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYE
40 50 60 70 80 90
230 240 250 260 270 280
pF1KE3 RSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDV
:::::::::::::::..:: .. .::.:.:::::::::::::::::.:::::::::::::
XP_016 RSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDV
100 110 120 130 140 150
290 300 310 320 330 340
pF1KE3 GGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTNRLRESLDLFESIWNNRWLRT
:::::::::::::::::::::.:.: :::::::::::.::::.:.:.::.::::::::::
XP_016 GGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRT
160 170 180 190 200 210
350 360 370 380 390 400
pF1KE3 ISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDATPDAGEDPKVTRAKFFIRDL
::.::::::::.::::::::::::::::::.: ::.::::::. ::::.:::::.::::
XP_016 ISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDE
220 230 240 250 260 270
410 420 430 440 450
pF1KE3 FLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLKQYELL
:::::::.:::.::::::::::::::::::::::::::::::::.:::::
XP_016 FLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL
280 290 300 310 320
>>XP_016883306 (OMIM: 102200,103580,139320,166350,174800 (320 aa)
initn: 1818 init1: 1818 opt: 1818 Z-score: 1539.4 bits: 293.6 E(85289): 5.2e-79
Smith-Waterman score: 1818; 79.7% identity (93.8% similar) in 320 aa overlap (139-458:1-320)
110 120 130 140 150 160
pF1KE3 LRDQKRDLQQTHRLLLLGAGESGKSTIVKQMRILHVNGFNPEEKKQKILDIRKNVKDAIV
:::::::::: .:: :. ::..:.:.::
XP_016 MRILHVNGFNGDEKATKVQDIKNNLKEAIE
10 20 30
170 180 190 200 210 220
pF1KE3 TIVSAMSTIIPPVPLANPENQFRSDYIKSIAPITDFEYSQEFFDHVKKLWDDEGVKACFE
:::.:::...::: ::::::::: ::: :. . ::.. ::..:.: ::.::::.::.:
XP_016 TIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYE
40 50 60 70 80 90
230 240 250 260 270 280
pF1KE3 RSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFETRFQVDKVNFHMFDV
:::::::::::::::..:: .. .::.:.:::::::::::::::::.:::::::::::::
XP_016 RSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDV
100 110 120 130 140 150
290 300 310 320 330 340
pF1KE3 GGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTNRLRESLDLFESIWNNRWLRT
:::::::::::::::::::::.:.: :::::::::::.::::.:.:.::.::::::::::
XP_016 GGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRT
160 170 180 190 200 210
350 360 370 380 390 400
pF1KE3 ISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDATPDAGEDPKVTRAKFFIRDL
::.::::::::.::::::::::::::::::.: ::.::::::. ::::.:::::.::::
XP_016 ISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDE
220 230 240 250 260 270
410 420 430 440 450
pF1KE3 FLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLKQYELL
:::::::.:::.::::::::::::::::::::::::::::::::.:::::
XP_016 FLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL
280 290 300 310 320
458 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 04:47:33 2016 done: Sun Nov 6 04:47:35 2016
Total Scan time: 9.960 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]