FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE3184, 422 aa
  1>>>pF1KE3184 422 - 422 aa - 422 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.7253+/-0.000833; mu= 15.6588+/- 0.050
 mean_var=77.2194+/-15.029, 0's: 0 Z-trim(107.3): 26  B-trim: 0 in 0/53
 Lambda= 0.145952
 statistics sampled from 9474 (9497) to 9474 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.669), E-opt: 0.2 (0.292), width:  16
 Scan time:  3.090

The best scores are:                                      opt bits E(32554)
CCDS5865.1 AGK gene_id:55750|Hs108|chr7            ( 422) 2821 603.5 1.3e-172
CCDS45785.1 SPHK1 gene_id:8877|Hs108|chr17         ( 384)  278 68.0 1.8e-11
CCDS59297.1 SPHK1 gene_id:8877|Hs108|chr17         ( 398)  278 68.0 1.9e-11
CCDS11744.1 SPHK1 gene_id:8877|Hs108|chr17         ( 470)  278 68.0 2.1e-11


>>CCDS5865.1 AGK gene_id:55750|Hs108|chr7                 (422 aa)
 initn: 2821 init1: 2821 opt: 2821  Z-score: 3212.7  bits: 603.5 E(32554): 1.3e-172
Smith-Waterman score: 2821; 100.0% identity (100.0% similar) in 422 aa overlap (1-422:1-422)

               10        20        30        40        50        60
pF1KE3 MTVFFKTLRNHWKKTTAGLCLLTWGGHWLYGKHCDNLLRRAACQEAQVFGNQLIPPNAQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 MTVFFKTLRNHWKKTTAGLCLLTWGGHWLYGKHCDNLLRRAACQEAQVFGNQLIPPNAQV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE3 KKATVFLNPAACKGKARTLFEKNAAPILHLSGMDVTIVKTDYEGQAKKLLELMENTDVII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 KKATVFLNPAACKGKARTLFEKNAAPILHLSGMDVTIVKTDYEGQAKKLLELMENTDVII
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE3 VAGGDGTLQEVVTGVLRRTDEATFSKIPIGFIPLGETSSLSHTLFAESGNKVQHITDATL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 VAGGDGTLQEVVTGVLRRTDEATFSKIPIGFIPLGETSSLSHTLFAESGNKVQHITDATL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE3 AIVKGETVPLDVLQIKGEKEQPVFAMTGLRWGSFRDAGVKVSKYWYLGPLKIKAAHFFST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 AIVKGETVPLDVLQIKGEKEQPVFAMTGLRWGSFRDAGVKVSKYWYLGPLKIKAAHFFST
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE3 LKEWPQTHQASISYTGPTERPPNEPEETPVQRPSLYRRILRRLASYWAQPQDALSQEVSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 LKEWPQTHQASISYTGPTERPPNEPEETPVQRPSLYRRILRRLASYWAQPQDALSQEVSP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE3 EVWKDVQLSTIELSITTRNNQLDPTSKEDFLNICIEPDTISKGDFITIGSRKVRNPKLHV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 EVWKDVQLSTIELSITTRNNQLDPTSKEDFLNICIEPDTISKGDFITIGSRKVRNPKLHV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE3 EGTECLQASQCTLLIPEGAGGSFSIDSEEYEAMPVEVKLLPRKLQFFCDPRKREQMLTSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 EGTECLQASQCTLLIPEGAGGSFSIDSEEYEAMPVEVKLLPRKLQFFCDPRKREQMLTSP
              370       380       390       400       410       420

         
pF1KE3 TQ
       ::
CCDS58 TQ
         

>>CCDS45785.1 SPHK1 gene_id:8877|Hs108|chr17              (384 aa)
 initn: 184 init1:  70 opt: 278  Z-score: 319.4  bits: 68.0 E(32554): 1.8e-11
Smith-Waterman score: 278; 26.5% identity (62.3% similar) in 215 aa overlap (62-270:16-227)

              40        50        60        70        80        90 
pF1KE3 KHCDNLLRRAACQEAQVFGNQLIPPNAQVKKATVFLNPAACKGKARTLFEKNAAPILHLS
                                     .. :.::: . ::::  ::.... :.:  .
CCDS45                MDPAGGPRGVLPRPCRVLVLLNPRGGKGKALQLFRSHVQPLLAEA
                              10        20        30        40     

             100       110         120       130       140         
pF1KE3 GMDVTIVKTDYEGQAKKLL--ELMENTDVIIVAGGDGTLQEVVTGVLRRTDEATFSKIPI
        .. :.. :. ...:..:.  : .   :...: .::: ..:::.:...: :  :  . :.
CCDS45 EISFTLMLTERRNHARELVRSEELGRWDALVVMSGDGLMHEVVNGLMERPDWETAIQKPL
          50        60        70        80        90       100     

     150       160        170          180       190       200     
pF1KE3 GFIPLGETSSLSHTLFAESG-NKVQH---ITDATLAIVKGETVPLDVLQIKGEKEQPVFA
         .: :  ..:. .:   .: ..: .   .:. :: . .    :...:...  .   .:.
CCDS45 CSLPAGSGNALAASLNHYAGYEQVTNEDLLTNCTLLLCRRLLSPMNLLSLHTASGLRLFS
         110       120       130       140       150       160     

         210       220       230       240       250       260     
pF1KE3 MTGLRWGSFRDAGVKVSKYWYLGPLKIKAAHFFSTLKEWPQTHQASISYTGPTERPPNEP
       . .: :: . :. ..  ::  :: ...  . :.       .:... ..:  :. :  .. 
CCDS45 VLSLAWGFIADVDLESEKYRRLGEMRFTLGTFLRLAAL--RTYRGRLAYL-PVGRVGSKT
         170       180       190       200         210        220  

         270       280       290       300       310       320     
pF1KE3 EETPVQRPSLYRRILRRLASYWAQPQDALSQEVSPEVWKDVQLSTIELSITTRNNQLDPT
         .::                                                       
CCDS45 PASPVVVQQGPVDAHLVPLEEPVPSHWTVVPDEDFVLVLALLHSHLGSEMFAAPMGRCAA
            230       240       250       260       270       280  

>>CCDS59297.1 SPHK1 gene_id:8877|Hs108|chr17              (398 aa)
 initn: 184 init1:  70 opt: 278  Z-score: 319.1  bits: 68.0 E(32554): 1.9e-11
Smith-Waterman score: 278; 26.5% identity (62.3% similar) in 215 aa overlap (62-270:30-241)

              40        50        60        70        80        90 
pF1KE3 KHCDNLLRRAACQEAQVFGNQLIPPNAQVKKATVFLNPAACKGKARTLFEKNAAPILHLS
                                     .. :.::: . ::::  ::.... :.:  .
CCDS59  MDPVVGCGRGLFGFVFSAGGPRGVLPRPCRVLVLLNPRGGKGKALQLFRSHVQPLLAEA
                10        20        30        40        50         

             100       110         120       130       140         
pF1KE3 GMDVTIVKTDYEGQAKKLL--ELMENTDVIIVAGGDGTLQEVVTGVLRRTDEATFSKIPI
        .. :.. :. ...:..:.  : .   :...: .::: ..:::.:...: :  :  . :.
CCDS59 EISFTLMLTERRNHARELVRSEELGRWDALVVMSGDGLMHEVVNGLMERPDWETAIQKPL
      60        70        80        90       100       110         

     150       160        170          180       190       200     
pF1KE3 GFIPLGETSSLSHTLFAESG-NKVQH---ITDATLAIVKGETVPLDVLQIKGEKEQPVFA
         .: :  ..:. .:   .: ..: .   .:. :: . .    :...:...  .   .:.
CCDS59 CSLPAGSGNALAASLNHYAGYEQVTNEDLLTNCTLLLCRRLLSPMNLLSLHTASGLRLFS
     120       130       140       150       160       170         

         210       220       230       240       250       260     
pF1KE3 MTGLRWGSFRDAGVKVSKYWYLGPLKIKAAHFFSTLKEWPQTHQASISYTGPTERPPNEP
       . .: :: . :. ..  ::  :: ...  . :.       .:... ..:  :. :  .. 
CCDS59 VLSLAWGFIADVDLESEKYRRLGEMRFTLGTFLRLAAL--RTYRGRLAYL-PVGRVGSKT
     180       190       200       210         220        230      

         270       280       290       300       310       320     
pF1KE3 EETPVQRPSLYRRILRRLASYWAQPQDALSQEVSPEVWKDVQLSTIELSITTRNNQLDPT
         .::                                                       
CCDS59 PASPVVVQQGPVDAHLVPLEEPVPSHWTVVPDEDFVLVLALLHSHLGSEMFAAPMGRCAA
        240       250       260       270       280       290      

>>CCDS11744.1 SPHK1 gene_id:8877|Hs108|chr17              (470 aa)
 initn: 184 init1:  70 opt: 278  Z-score: 318.1  bits: 68.0 E(32554): 2.1e-11
Smith-Waterman score: 278; 26.5% identity (62.3% similar) in 215 aa overlap (62-270:102-313)

              40        50        60        70        80        90 
pF1KE3 KHCDNLLRRAACQEAQVFGNQLIPPNAQVKKATVFLNPAACKGKARTLFEKNAAPILHLS
                                     .. :.::: . ::::  ::.... :.:  .
CCDS11 TAPGTPWQREPRVEVMDPAGGPRGVLPRPCRVLVLLNPRGGKGKALQLFRSHVQPLLAEA
              80        90       100       110       120       130 

             100       110         120       130       140         
pF1KE3 GMDVTIVKTDYEGQAKKLL--ELMENTDVIIVAGGDGTLQEVVTGVLRRTDEATFSKIPI
        .. :.. :. ...:..:.  : .   :...: .::: ..:::.:...: :  :  . :.
CCDS11 EISFTLMLTERRNHARELVRSEELGRWDALVVMSGDGLMHEVVNGLMERPDWETAIQKPL
             140       150       160       170       180       190 

     150       160        170          180       190       200     
pF1KE3 GFIPLGETSSLSHTLFAESG-NKVQH---ITDATLAIVKGETVPLDVLQIKGEKEQPVFA
         .: :  ..:. .:   .: ..: .   .:. :: . .    :...:...  .   .:.
CCDS11 CSLPAGSGNALAASLNHYAGYEQVTNEDLLTNCTLLLCRRLLSPMNLLSLHTASGLRLFS
             200       210       220       230       240       250 

         210       220       230       240       250       260     
pF1KE3 MTGLRWGSFRDAGVKVSKYWYLGPLKIKAAHFFSTLKEWPQTHQASISYTGPTERPPNEP
       . .: :: . :. ..  ::  :: ...  . :.       .:... ..:  :. :  .. 
CCDS11 VLSLAWGFIADVDLESEKYRRLGEMRFTLGTFLRLAAL--RTYRGRLAYL-PVGRVGSKT
             260       270       280         290        300        

         270       280       290       300       310       320     
pF1KE3 EETPVQRPSLYRRILRRLASYWAQPQDALSQEVSPEVWKDVQLSTIELSITTRNNQLDPT
         .::                                                       
CCDS11 PASPVVVQQGPVDAHLVPLEEPVPSHWTVVPDEDFVLVLALLHSHLGSEMFAAPMGRCAA
      310       320       330       340       350       360        




422 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 01:37:40 2016 done: Sun Nov  6 01:37:40 2016
 Total Scan time:  3.090 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]