Result of FASTA (omim) for
pFN21AE3181
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3181, 418 aa
1>>>pF1KE3181 418 - 418 aa - 418 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3624+/-0.000351; mu= 17.4396+/- 0.022
mean_var=76.6907+/-15.702, 0's: 0 Z-trim(114.7): 23 B-trim: 88 in 1/50
Lambda= 0.146455
statistics sampled from 24602 (24625) to 24602 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.657), E-opt: 0.2 (0.289), width: 16
Scan time: 7.830
The best scores are: opt bits E(85289)
XP_011531296 (OMIM: 614797) PREDICTED: E3 ubiquiti ( 418) 2921 626.7 3.3e-179
XP_016860009 (OMIM: 614797) PREDICTED: E3 ubiquiti ( 418) 2921 626.7 3.3e-179
NP_065702 (OMIM: 614797) E3 ubiquitin-protein liga ( 418) 2921 626.7 3.3e-179
NP_067078 (OMIM: 614798) E3 ubiquitin-protein liga ( 420) 2481 533.7 3.2e-151
XP_016860010 (OMIM: 614797) PREDICTED: E3 ubiquiti ( 352) 2461 529.4 5.2e-150
XP_016876967 (OMIM: 614798) PREDICTED: E3 ubiquiti ( 407) 2379 512.2 9.6e-145
XP_005264494 (OMIM: 614797) PREDICTED: E3 ubiquiti ( 320) 2269 488.8 7.9e-138
XP_011531298 (OMIM: 614797) PREDICTED: E3 ubiquiti ( 320) 2269 488.8 7.9e-138
NP_001091980 (OMIM: 609827) E3 ubiquitin-protein l ( 445) 2138 461.3 2.2e-129
NP_659502 (OMIM: 609827) E3 ubiquitin-protein liga ( 469) 2040 440.6 3.9e-123
XP_011543186 (OMIM: 609827) PREDICTED: E3 ubiquiti ( 469) 2040 440.6 3.9e-123
XP_011535294 (OMIM: 614798) PREDICTED: E3 ubiquiti ( 320) 1937 418.7 1e-116
XP_006720274 (OMIM: 614798) PREDICTED: E3 ubiquiti ( 320) 1937 418.7 1e-116
XP_011535292 (OMIM: 614798) PREDICTED: E3 ubiquiti ( 320) 1937 418.7 1e-116
XP_016876968 (OMIM: 614798) PREDICTED: E3 ubiquiti ( 320) 1937 418.7 1e-116
NP_001230065 (OMIM: 609827) E3 ubiquitin-protein l ( 362) 1899 410.7 3e-114
NP_001230064 (OMIM: 609827) E3 ubiquitin-protein l ( 406) 1894 409.7 6.8e-114
XP_011531299 (OMIM: 614797) PREDICTED: E3 ubiquiti ( 239) 1732 375.3 9e-104
XP_016872954 (OMIM: 609827) PREDICTED: E3 ubiquiti ( 320) 1716 372.0 1.2e-102
XP_005267947 (OMIM: 614798) PREDICTED: E3 ubiquiti ( 247) 1305 285.1 1.3e-76
>>XP_011531296 (OMIM: 614797) PREDICTED: E3 ubiquitin-pr (418 aa)
initn: 2921 init1: 2921 opt: 2921 Z-score: 3338.3 bits: 626.7 E(85289): 3.3e-179
Smith-Waterman score: 2921; 100.0% identity (100.0% similar) in 418 aa overlap (1-418:1-418)
10 20 30 40 50 60
pF1KE3 MFSPDQENHPSKAPVKYGELIVLGYNGSLPNGDRGRRKSRFALFKRPKANGVKPSTVHIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MFSPDQENHPSKAPVKYGELIVLGYNGSLPNGDRGRRKSRFALFKRPKANGVKPSTVHIA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 CTPQAAKAISNKDQHSISYTLSRAQTVVVEYTHDSNTDMFQIGRSTESPIDFVVTDTVPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CTPQAAKAISNKDQHSISYTLSRAQTVVVEYTHDSNTDMFQIGRSTESPIDFVVTDTVPG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 SQSNSDTQSVQSTISRFACRIICERNPPFTARIYAAGFDSSKNIFLGEKAAKWKTSDGQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQSNSDTQSVQSTISRFACRIICERNPPFTARIYAAGFDSSKNIFLGEKAAKWKTSDGQM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 DGLTTNGVLVMHPRNGFTEDSKPGIWREISVCGNVFSLRETRSAQQRGKMVEIETNQLQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGLTTNGVLVMHPRNGFTEDSKPGIWREISVCGNVFSLRETRSAQQRGKMVEIETNQLQD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 GSLIDLCGATLLWRTAEGLSHTPTVKHLEALRQEINAARPQCPVGFNTLAFPSMKRKDVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSLIDLCGATLLWRTAEGLSHTPTVKHLEALRQEINAARPQCPVGFNTLAFPSMKRKDVV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 DEKQPWVYLNCGHVHGYHNWGNKEERDGKDRECPMCRSVGPYVPLWLGCEAGFYVDAGPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEKQPWVYLNCGHVHGYHNWGNKEERDGKDRECPMCRSVGPYVPLWLGCEAGFYVDAGPP
310 320 330 340 350 360
370 380 390 400 410
pF1KE3 THAFSPCGHVCSEKTTAYWSQIPLPHGTHTFHAACPFCAHQLAGEQGYIRLIFQGPLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 THAFSPCGHVCSEKTTAYWSQIPLPHGTHTFHAACPFCAHQLAGEQGYIRLIFQGPLD
370 380 390 400 410
>>XP_016860009 (OMIM: 614797) PREDICTED: E3 ubiquitin-pr (418 aa)
initn: 2921 init1: 2921 opt: 2921 Z-score: 3338.3 bits: 626.7 E(85289): 3.3e-179
Smith-Waterman score: 2921; 100.0% identity (100.0% similar) in 418 aa overlap (1-418:1-418)
10 20 30 40 50 60
pF1KE3 MFSPDQENHPSKAPVKYGELIVLGYNGSLPNGDRGRRKSRFALFKRPKANGVKPSTVHIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MFSPDQENHPSKAPVKYGELIVLGYNGSLPNGDRGRRKSRFALFKRPKANGVKPSTVHIA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 CTPQAAKAISNKDQHSISYTLSRAQTVVVEYTHDSNTDMFQIGRSTESPIDFVVTDTVPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CTPQAAKAISNKDQHSISYTLSRAQTVVVEYTHDSNTDMFQIGRSTESPIDFVVTDTVPG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 SQSNSDTQSVQSTISRFACRIICERNPPFTARIYAAGFDSSKNIFLGEKAAKWKTSDGQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQSNSDTQSVQSTISRFACRIICERNPPFTARIYAAGFDSSKNIFLGEKAAKWKTSDGQM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 DGLTTNGVLVMHPRNGFTEDSKPGIWREISVCGNVFSLRETRSAQQRGKMVEIETNQLQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGLTTNGVLVMHPRNGFTEDSKPGIWREISVCGNVFSLRETRSAQQRGKMVEIETNQLQD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 GSLIDLCGATLLWRTAEGLSHTPTVKHLEALRQEINAARPQCPVGFNTLAFPSMKRKDVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSLIDLCGATLLWRTAEGLSHTPTVKHLEALRQEINAARPQCPVGFNTLAFPSMKRKDVV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 DEKQPWVYLNCGHVHGYHNWGNKEERDGKDRECPMCRSVGPYVPLWLGCEAGFYVDAGPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEKQPWVYLNCGHVHGYHNWGNKEERDGKDRECPMCRSVGPYVPLWLGCEAGFYVDAGPP
310 320 330 340 350 360
370 380 390 400 410
pF1KE3 THAFSPCGHVCSEKTTAYWSQIPLPHGTHTFHAACPFCAHQLAGEQGYIRLIFQGPLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 THAFSPCGHVCSEKTTAYWSQIPLPHGTHTFHAACPFCAHQLAGEQGYIRLIFQGPLD
370 380 390 400 410
>>NP_065702 (OMIM: 614797) E3 ubiquitin-protein ligase p (418 aa)
initn: 2921 init1: 2921 opt: 2921 Z-score: 3338.3 bits: 626.7 E(85289): 3.3e-179
Smith-Waterman score: 2921; 100.0% identity (100.0% similar) in 418 aa overlap (1-418:1-418)
10 20 30 40 50 60
pF1KE3 MFSPDQENHPSKAPVKYGELIVLGYNGSLPNGDRGRRKSRFALFKRPKANGVKPSTVHIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MFSPDQENHPSKAPVKYGELIVLGYNGSLPNGDRGRRKSRFALFKRPKANGVKPSTVHIA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 CTPQAAKAISNKDQHSISYTLSRAQTVVVEYTHDSNTDMFQIGRSTESPIDFVVTDTVPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 CTPQAAKAISNKDQHSISYTLSRAQTVVVEYTHDSNTDMFQIGRSTESPIDFVVTDTVPG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 SQSNSDTQSVQSTISRFACRIICERNPPFTARIYAAGFDSSKNIFLGEKAAKWKTSDGQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SQSNSDTQSVQSTISRFACRIICERNPPFTARIYAAGFDSSKNIFLGEKAAKWKTSDGQM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 DGLTTNGVLVMHPRNGFTEDSKPGIWREISVCGNVFSLRETRSAQQRGKMVEIETNQLQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 DGLTTNGVLVMHPRNGFTEDSKPGIWREISVCGNVFSLRETRSAQQRGKMVEIETNQLQD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 GSLIDLCGATLLWRTAEGLSHTPTVKHLEALRQEINAARPQCPVGFNTLAFPSMKRKDVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 GSLIDLCGATLLWRTAEGLSHTPTVKHLEALRQEINAARPQCPVGFNTLAFPSMKRKDVV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 DEKQPWVYLNCGHVHGYHNWGNKEERDGKDRECPMCRSVGPYVPLWLGCEAGFYVDAGPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 DEKQPWVYLNCGHVHGYHNWGNKEERDGKDRECPMCRSVGPYVPLWLGCEAGFYVDAGPP
310 320 330 340 350 360
370 380 390 400 410
pF1KE3 THAFSPCGHVCSEKTTAYWSQIPLPHGTHTFHAACPFCAHQLAGEQGYIRLIFQGPLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 THAFSPCGHVCSEKTTAYWSQIPLPHGTHTFHAACPFCAHQLAGEQGYIRLIFQGPLD
370 380 390 400 410
>>NP_067078 (OMIM: 614798) E3 ubiquitin-protein ligase p (420 aa)
initn: 2515 init1: 2427 opt: 2481 Z-score: 2835.8 bits: 533.7 E(85289): 3.2e-151
Smith-Waterman score: 2481; 81.4% identity (94.8% similar) in 420 aa overlap (1-418:1-420)
10 20 30 40 50
pF1KE3 MFSPDQENH--PSKAPVKYGELIVLGYNGSLPNGDRGRRKSRFALFKRPKANGVKPSTVH
:::: ::.: :.: :::::::.::::::.:::::::::::::::.::::::::::::::
NP_067 MFSPGQEEHCAPNKEPVKYGELVVLGYNGALPNGDRGRRKSRFALYKRPKANGVKPSTVH
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 IACTPQAAKAISNKDQHSISYTLSRAQTVVVEYTHDSNTDMFQIGRSTESPIDFVVTDTV
. ::::.:::: : :::::::::: ::::::::::..:::::.:::::::::::::::.
NP_067 VISTPQASKAISCKGQHSISYTLSRNQTVVVEYTHDKDTDMFQVGRSTESPIDFVVTDTI
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 PGSQSNSDTQSVQSTISRFACRIICERNPPFTARIYAAGFDSSKNIFLGEKAAKWKTSDG
:::.....: .:::::::::::.:.:: :.::::.::::::::::::::::::::. ::
NP_067 SGSQNTDEAQITQSTISRFACRIVCDRNEPYTARIFAAGFDSSKNIFLGEKAAKWKNPDG
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE3 QMDGLTTNGVLVMHPRNGFTEDSKPGIWREISVCGNVFSLRETRSAQQRGKMVEIETNQL
.:::::::::::::::.::::.:.::.::::::::.:..::::::::::::.:: ::: :
NP_067 HMDGLTTNGVLVMHPRGGFTEESQPGVWREISVCGDVYTLRETRSAQQRGKLVESETNVL
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE3 QDGSLIDLCGATLLWRTAEGLSHTPTVKHLEALRQEINAARPQCPVGFNTLAFPSMKRKD
::::::::::::::::::.:: :::: ::.:::::::::::::::::.:::::::..::.
NP_067 QDGSLIDLCGATLLWRTADGLFHTPTQKHIEALRQEINAARPQCPVGLNTLAFPSINRKE
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE3 VVDEKQPWVYLNCGHVHGYHNWGNKEERDGKDRECPMCRSVGPYVPLWLGCEAGFYVDAG
::.:::::.::.:::::::::::.. . ....:::::::.::::::::::::::::::::
NP_067 VVEEKQPWAYLSCGHVHGYHNWGHRSDTEANERECPMCRTVGPYVPLWLGCEAGFYVDAG
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE3 PPTHAFSPCGHVCSEKTTAYWSQIPLPHGTHTFHAACPFCAHQLAGEQGYIRLIFQGPLD
::::::.:::::::::.. ::::::::::::.::::::::: ::.:::. :.::::::.:
NP_067 PPTHAFTPCGHVCSEKSAKYWSQIPLPHGTHAFHAACPFCATQLVGEQNCIKLIFQGPID
370 380 390 400 410 420
>>XP_016860010 (OMIM: 614797) PREDICTED: E3 ubiquitin-pr (352 aa)
initn: 2461 init1: 2461 opt: 2461 Z-score: 2814.1 bits: 529.4 E(85289): 5.2e-150
Smith-Waterman score: 2461; 100.0% identity (100.0% similar) in 351 aa overlap (68-418:2-352)
40 50 60 70 80 90
pF1KE3 KSRFALFKRPKANGVKPSTVHIACTPQAAKAISNKDQHSISYTLSRAQTVVVEYTHDSNT
::::::::::::::::::::::::::::::
XP_016 MAISNKDQHSISYTLSRAQTVVVEYTHDSNT
10 20 30
100 110 120 130 140 150
pF1KE3 DMFQIGRSTESPIDFVVTDTVPGSQSNSDTQSVQSTISRFACRIICERNPPFTARIYAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DMFQIGRSTESPIDFVVTDTVPGSQSNSDTQSVQSTISRFACRIICERNPPFTARIYAAG
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE3 FDSSKNIFLGEKAAKWKTSDGQMDGLTTNGVLVMHPRNGFTEDSKPGIWREISVCGNVFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FDSSKNIFLGEKAAKWKTSDGQMDGLTTNGVLVMHPRNGFTEDSKPGIWREISVCGNVFS
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE3 LRETRSAQQRGKMVEIETNQLQDGSLIDLCGATLLWRTAEGLSHTPTVKHLEALRQEINA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRETRSAQQRGKMVEIETNQLQDGSLIDLCGATLLWRTAEGLSHTPTVKHLEALRQEINA
160 170 180 190 200 210
280 290 300 310 320 330
pF1KE3 ARPQCPVGFNTLAFPSMKRKDVVDEKQPWVYLNCGHVHGYHNWGNKEERDGKDRECPMCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARPQCPVGFNTLAFPSMKRKDVVDEKQPWVYLNCGHVHGYHNWGNKEERDGKDRECPMCR
220 230 240 250 260 270
340 350 360 370 380 390
pF1KE3 SVGPYVPLWLGCEAGFYVDAGPPTHAFSPCGHVCSEKTTAYWSQIPLPHGTHTFHAACPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVGPYVPLWLGCEAGFYVDAGPPTHAFSPCGHVCSEKTTAYWSQIPLPHGTHTFHAACPF
280 290 300 310 320 330
400 410
pF1KE3 CAHQLAGEQGYIRLIFQGPLD
:::::::::::::::::::::
XP_016 CAHQLAGEQGYIRLIFQGPLD
340 350
>>XP_016876967 (OMIM: 614798) PREDICTED: E3 ubiquitin-pr (407 aa)
initn: 2425 init1: 2375 opt: 2379 Z-score: 2719.6 bits: 512.2 E(85289): 9.6e-145
Smith-Waterman score: 2379; 81.9% identity (95.5% similar) in 398 aa overlap (21-418:10-407)
10 20 30 40 50 60
pF1KE3 MFSPDQENHPSKAPVKYGELIVLGYNGSLPNGDRGRRKSRFALFKRPKANGVKPSTVHIA
.::::::.:::::::::::::::.::::::::::::::.
XP_016 MLAWPFHSNVVLGYNGALPNGDRGRRKSRFALYKRPKANGVKPSTVHVI
10 20 30 40
70 80 90 100 110 120
pF1KE3 CTPQAAKAISNKDQHSISYTLSRAQTVVVEYTHDSNTDMFQIGRSTESPIDFVVTDTVPG
::::.:::: : :::::::::: ::::::::::..:::::.:::::::::::::::. :
XP_016 STPQASKAISCKGQHSISYTLSRNQTVVVEYTHDKDTDMFQVGRSTESPIDFVVTDTISG
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE3 SQSNSDTQSVQSTISRFACRIICERNPPFTARIYAAGFDSSKNIFLGEKAAKWKTSDGQM
::.....: .:::::::::::.:.:: :.::::.::::::::::::::::::::. ::.:
XP_016 SQNTDEAQITQSTISRFACRIVCDRNEPYTARIFAAGFDSSKNIFLGEKAAKWKNPDGHM
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE3 DGLTTNGVLVMHPRNGFTEDSKPGIWREISVCGNVFSLRETRSAQQRGKMVEIETNQLQD
::::::::::::::.::::.:.::.::::::::.:..::::::::::::.:: ::: :::
XP_016 DGLTTNGVLVMHPRGGFTEESQPGVWREISVCGDVYTLRETRSAQQRGKLVESETNVLQD
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE3 GSLIDLCGATLLWRTAEGLSHTPTVKHLEALRQEINAARPQCPVGFNTLAFPSMKRKDVV
::::::::::::::::.:: :::: ::.:::::::::::::::::.:::::::..::.::
XP_016 GSLIDLCGATLLWRTADGLFHTPTQKHIEALRQEINAARPQCPVGLNTLAFPSINRKEVV
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE3 DEKQPWVYLNCGHVHGYHNWGNKEERDGKDRECPMCRSVGPYVPLWLGCEAGFYVDAGPP
.:::::.::.:::::::::::.. . ....:::::::.::::::::::::::::::::::
XP_016 EEKQPWAYLSCGHVHGYHNWGHRSDTEANERECPMCRTVGPYVPLWLGCEAGFYVDAGPP
290 300 310 320 330 340
370 380 390 400 410
pF1KE3 THAFSPCGHVCSEKTTAYWSQIPLPHGTHTFHAACPFCAHQLAGEQGYIRLIFQGPLD
::::.:::::::::.. ::::::::::::.::::::::: ::.:::. :.::::::.:
XP_016 THAFTPCGHVCSEKSAKYWSQIPLPHGTHAFHAACPFCATQLVGEQNCIKLIFQGPID
350 360 370 380 390 400
>>XP_005264494 (OMIM: 614797) PREDICTED: E3 ubiquitin-pr (320 aa)
initn: 2269 init1: 2269 opt: 2269 Z-score: 2595.4 bits: 488.8 E(85289): 7.9e-138
Smith-Waterman score: 2269; 100.0% identity (100.0% similar) in 320 aa overlap (99-418:1-320)
70 80 90 100 110 120
pF1KE3 ISNKDQHSISYTLSRAQTVVVEYTHDSNTDMFQIGRSTESPIDFVVTDTVPGSQSNSDTQ
::::::::::::::::::::::::::::::
XP_005 MFQIGRSTESPIDFVVTDTVPGSQSNSDTQ
10 20 30
130 140 150 160 170 180
pF1KE3 SVQSTISRFACRIICERNPPFTARIYAAGFDSSKNIFLGEKAAKWKTSDGQMDGLTTNGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVQSTISRFACRIICERNPPFTARIYAAGFDSSKNIFLGEKAAKWKTSDGQMDGLTTNGV
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE3 LVMHPRNGFTEDSKPGIWREISVCGNVFSLRETRSAQQRGKMVEIETNQLQDGSLIDLCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LVMHPRNGFTEDSKPGIWREISVCGNVFSLRETRSAQQRGKMVEIETNQLQDGSLIDLCG
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE3 ATLLWRTAEGLSHTPTVKHLEALRQEINAARPQCPVGFNTLAFPSMKRKDVVDEKQPWVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ATLLWRTAEGLSHTPTVKHLEALRQEINAARPQCPVGFNTLAFPSMKRKDVVDEKQPWVY
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE3 LNCGHVHGYHNWGNKEERDGKDRECPMCRSVGPYVPLWLGCEAGFYVDAGPPTHAFSPCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LNCGHVHGYHNWGNKEERDGKDRECPMCRSVGPYVPLWLGCEAGFYVDAGPPTHAFSPCG
220 230 240 250 260 270
370 380 390 400 410
pF1KE3 HVCSEKTTAYWSQIPLPHGTHTFHAACPFCAHQLAGEQGYIRLIFQGPLD
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HVCSEKTTAYWSQIPLPHGTHTFHAACPFCAHQLAGEQGYIRLIFQGPLD
280 290 300 310 320
>>XP_011531298 (OMIM: 614797) PREDICTED: E3 ubiquitin-pr (320 aa)
initn: 2269 init1: 2269 opt: 2269 Z-score: 2595.4 bits: 488.8 E(85289): 7.9e-138
Smith-Waterman score: 2269; 100.0% identity (100.0% similar) in 320 aa overlap (99-418:1-320)
70 80 90 100 110 120
pF1KE3 ISNKDQHSISYTLSRAQTVVVEYTHDSNTDMFQIGRSTESPIDFVVTDTVPGSQSNSDTQ
::::::::::::::::::::::::::::::
XP_011 MFQIGRSTESPIDFVVTDTVPGSQSNSDTQ
10 20 30
130 140 150 160 170 180
pF1KE3 SVQSTISRFACRIICERNPPFTARIYAAGFDSSKNIFLGEKAAKWKTSDGQMDGLTTNGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVQSTISRFACRIICERNPPFTARIYAAGFDSSKNIFLGEKAAKWKTSDGQMDGLTTNGV
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE3 LVMHPRNGFTEDSKPGIWREISVCGNVFSLRETRSAQQRGKMVEIETNQLQDGSLIDLCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVMHPRNGFTEDSKPGIWREISVCGNVFSLRETRSAQQRGKMVEIETNQLQDGSLIDLCG
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE3 ATLLWRTAEGLSHTPTVKHLEALRQEINAARPQCPVGFNTLAFPSMKRKDVVDEKQPWVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATLLWRTAEGLSHTPTVKHLEALRQEINAARPQCPVGFNTLAFPSMKRKDVVDEKQPWVY
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE3 LNCGHVHGYHNWGNKEERDGKDRECPMCRSVGPYVPLWLGCEAGFYVDAGPPTHAFSPCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNCGHVHGYHNWGNKEERDGKDRECPMCRSVGPYVPLWLGCEAGFYVDAGPPTHAFSPCG
220 230 240 250 260 270
370 380 390 400 410
pF1KE3 HVCSEKTTAYWSQIPLPHGTHTFHAACPFCAHQLAGEQGYIRLIFQGPLD
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HVCSEKTTAYWSQIPLPHGTHTFHAACPFCAHQLAGEQGYIRLIFQGPLD
280 290 300 310 320
>>NP_001091980 (OMIM: 609827) E3 ubiquitin-protein ligas (445 aa)
initn: 1061 init1: 1061 opt: 2138 Z-score: 2443.8 bits: 461.3 E(85289): 2.2e-129
Smith-Waterman score: 2138; 70.5% identity (88.5% similar) in 417 aa overlap (3-418:30-445)
10 20 30
pF1KE3 MFSPDQENHPSKAPVKYGELIVLGYNGSLPNGD
:: .. .:.. :.:::::::::::: : .::
NP_001 MVLEGNPEVGSPRTSDLQHRGNKGSCVLSSPGEDAQPGEEPIKYGELIVLGYNGCLASGD
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE3 RGRRKSRFALFKRPKANGVKPSTVHIACTPQAAKAISNKDQHSISYTLSRAQTVVVEYTH
.:::.::.:: .: .::::::...: :: ..::.::. ::::::::::...:.:::::
NP_001 KGRRRSRLALSRRSHANGVKPDVMHHISTPLVSKALSNRGQHSISYTLSRSHSVIVEYTH
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE3 DSNTDMFQIGRSTESPIDFVVTDTVPGSQSNSDTQSVQSTISRFACRIICERNPPFTARI
::.:::::::::::. :::::::: ::. . .. :.::::::.::::.:.: ::.::::
NP_001 DSDTDMFQIGRSTENMIDFVVTDTSPGG-GAAEGPSAQSTISRYACRILCDRRPPYTARI
130 140 150 160 170
160 170 180 190 200 210
pF1KE3 YAAGFDSSKNIFLGEKAAKWKTSDGQMDGLTTNGVLVMHPRNGFTEDSKPGIWREISVCG
::::::.:.::::::.::::.: :: :::::::::::::: .::.::: ::.::::::::
NP_001 YAAGFDASSNIFLGERAAKWRTPDGLMDGLTTNGVLVMHPAGGFSEDSAPGVWREISVCG
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE3 NVFSLRETRSAQQRGKMVEIETNQLQDGSLIDLCGATLLWRTAEGLSHTPTVKHLEALRQ
::..::..::::::::.:: :.: :::::::::::::::::: :: ..::.:.::: ::
NP_001 NVYTLRDSRSAQQRGKLVENESNVLQDGSLIDLCGATLLWRTPAGLLRAPTLKQLEAQRQ
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE3 EINAARPQCPVGFNTLAFPSMKR-KDVVDEKQPWVYLNCGHVHGYHNWGNKEERDGKDRE
: ::::::::::..:::::: : . . :..:::::. ::::::::.:: ..:: ..::
NP_001 EANAARPQCPVGLSTLAFPSPARGRTAPDKQQPWVYVRCGHVHGYHGWGCRRERGPQERE
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE3 CPMCRSVGPYVPLWLGCEAGFYVDAGPPTHAFSPCGHVCSEKTTAYWSQIPLPHGTHTFH
::.:: :::::::::: :::. .: :::.:::.::::::::::. ::.: :::::::.::
NP_001 CPLCRLVGPYVPLWLGQEAGLCLDPGPPSHAFAPCGHVCSEKTARYWAQTPLPHGTHAFH
360 370 380 390 400 410
400 410
pF1KE3 AACPFCAHQLAGEQGYIRLIFQGPLD
::::::. :.::.: .:::::::::
NP_001 AACPFCGAWLTGEHGCVRLIFQGPLD
420 430 440
>>NP_659502 (OMIM: 609827) E3 ubiquitin-protein ligase p (469 aa)
initn: 1047 init1: 963 opt: 2040 Z-score: 2331.6 bits: 440.6 E(85289): 3.9e-123
Smith-Waterman score: 2080; 66.7% identity (83.7% similar) in 441 aa overlap (3-418:30-469)
10 20
pF1KE3 MFSPDQENHPSKAPVKYGELIVLG---------
:: .. .:.. :.:::::::::
NP_659 MVLEGNPEVGSPRTSDLQHRGNKGSCVLSSPGEDAQPGEEPIKYGELIVLGCCEEGGEET
10 20 30 40 50 60
30 40 50 60
pF1KE3 ---------------YNGSLPNGDRGRRKSRFALFKRPKANGVKPSTVHIACTPQAAKAI
::: : .::.:::.::.:: .: .::::::...: :: ..::.
NP_659 EAQRGEVTGPRAHSCYNGCLASGDKGRRRSRLALSRRSHANGVKPDVMHHISTPLVSKAL
70 80 90 100 110 120
70 80 90 100 110 120
pF1KE3 SNKDQHSISYTLSRAQTVVVEYTHDSNTDMFQIGRSTESPIDFVVTDTVPGSQSNSDTQS
::. ::::::::::...:.:::::::.:::::::::::. :::::::: ::. . .. :
NP_659 SNRGQHSISYTLSRSHSVIVEYTHDSDTDMFQIGRSTENMIDFVVTDTSPGG-GAAEGPS
130 140 150 160 170
130 140 150 160 170 180
pF1KE3 VQSTISRFACRIICERNPPFTARIYAAGFDSSKNIFLGEKAAKWKTSDGQMDGLTTNGVL
.::::::.::::.:.: ::.::::::::::.:.::::::.::::.: :: ::::::::::
NP_659 AQSTISRYACRILCDRRPPYTARIYAAGFDASSNIFLGERAAKWRTPDGLMDGLTTNGVL
180 190 200 210 220 230
190 200 210 220 230 240
pF1KE3 VMHPRNGFTEDSKPGIWREISVCGNVFSLRETRSAQQRGKMVEIETNQLQDGSLIDLCGA
:::: .::.::: ::.::::::::::..::..::::::::.:: :.: ::::::::::::
NP_659 VMHPAGGFSEDSAPGVWREISVCGNVYTLRDSRSAQQRGKLVENESNVLQDGSLIDLCGA
240 250 260 270 280 290
250 260 270 280 290 300
pF1KE3 TLLWRTAEGLSHTPTVKHLEALRQEINAARPQCPVGFNTLAFPSMKR-KDVVDEKQPWVY
:::::: :: ..::.:.::: ::: ::::::::::..:::::: : . . :..:::::
NP_659 TLLWRTPAGLLRAPTLKQLEAQRQEANAARPQCPVGLSTLAFPSPARGRTAPDKQQPWVY
300 310 320 330 340 350
310 320 330 340 350 360
pF1KE3 LNCGHVHGYHNWGNKEERDGKDRECPMCRSVGPYVPLWLGCEAGFYVDAGPPTHAFSPCG
. ::::::::.:: ..:: ..::::.:: :::::::::: :::. .: :::.:::.:::
NP_659 VRCGHVHGYHGWGCRRERGPQERECPLCRLVGPYVPLWLGQEAGLCLDPGPPSHAFAPCG
360 370 380 390 400 410
370 380 390 400 410
pF1KE3 HVCSEKTTAYWSQIPLPHGTHTFHAACPFCAHQLAGEQGYIRLIFQGPLD
:::::::. ::.: :::::::.::::::::. :.::.: .:::::::::
NP_659 HVCSEKTARYWAQTPLPHGTHAFHAACPFCGAWLTGEHGCVRLIFQGPLD
420 430 440 450 460
418 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 01:58:26 2016 done: Sun Nov 6 01:58:28 2016
Total Scan time: 7.830 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]