Result of FASTA (omim) for
pFN21AE3158
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3158, 376 aa
1>>>pF1KE3158 376 - 376 aa - 376 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7510+/-0.000431; mu= 14.8923+/- 0.027
mean_var=104.6922+/-21.492, 0's: 0 Z-trim(112.4): 197 B-trim: 1186 in 2/54
Lambda= 0.125348
statistics sampled from 21130 (21381) to 21130 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.614), E-opt: 0.2 (0.251), width: 16
Scan time: 6.420
The best scores are: opt bits E(85289)
NP_078815 (OMIM: 300439) E3 ubiquitin-protein liga ( 402) 1068 204.2 4.2e-52
NP_919445 (OMIM: 300439) E3 ubiquitin-protein liga ( 428) 991 190.3 6.9e-48
NP_001307292 (OMIM: 610431) E3 ubiquitin-protein l ( 315) 270 59.8 9.8e-09
NP_001307294 (OMIM: 610431) E3 ubiquitin-protein l ( 315) 270 59.8 9.8e-09
NP_001307291 (OMIM: 610431) E3 ubiquitin-protein l ( 315) 270 59.8 9.8e-09
NP_001307293 (OMIM: 610431) E3 ubiquitin-protein l ( 315) 270 59.8 9.8e-09
NP_001307287 (OMIM: 610431) E3 ubiquitin-protein l ( 350) 270 59.9 1.1e-08
NP_056343 (OMIM: 610431) E3 ubiquitin-protein liga ( 350) 270 59.9 1.1e-08
NP_001307290 (OMIM: 610431) E3 ubiquitin-protein l ( 350) 270 59.9 1.1e-08
NP_001307289 (OMIM: 610431) E3 ubiquitin-protein l ( 350) 270 59.9 1.1e-08
NP_001307288 (OMIM: 610431) E3 ubiquitin-protein l ( 350) 270 59.9 1.1e-08
NP_001307286 (OMIM: 610431) E3 ubiquitin-protein l ( 350) 270 59.9 1.1e-08
NP_001307285 (OMIM: 610431) E3 ubiquitin-protein l ( 350) 270 59.9 1.1e-08
XP_016879916 (OMIM: 610431) PREDICTED: E3 ubiquiti ( 350) 270 59.9 1.1e-08
NP_899237 (OMIM: 609247) E3 ubiquitin-protein liga ( 381) 264 58.8 2.4e-08
XP_011510675 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 381) 264 58.8 2.4e-08
XP_016861143 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 381) 264 58.8 2.4e-08
XP_016861144 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 381) 264 58.8 2.4e-08
NP_009213 (OMIM: 609247) E3 ubiquitin-protein liga ( 381) 264 58.8 2.4e-08
XP_011510676 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 381) 264 58.8 2.4e-08
XP_016861150 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 193) 217 50.1 5.3e-06
XP_016861149 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 250) 216 50.0 7.2e-06
NP_859061 (OMIM: 612063) E3 ubiquitin-protein liga ( 429) 219 50.7 7.3e-06
XP_016861147 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 216 50.0 7.5e-06
XP_005247149 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 216 50.0 7.5e-06
XP_016861146 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 216 50.0 7.5e-06
XP_016861148 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 216 50.0 7.5e-06
XP_016861145 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 216 50.0 7.5e-06
XP_011510678 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 216 50.0 7.5e-06
NP_115549 (OMIM: 612062) E3 ubiquitin-protein liga ( 836) 220 51.2 1e-05
XP_011528737 (OMIM: 612062) PREDICTED: E3 ubiquiti ( 841) 220 51.2 1.1e-05
XP_011528739 (OMIM: 612062) PREDICTED: E3 ubiquiti ( 841) 220 51.2 1.1e-05
XP_016884479 (OMIM: 612062) PREDICTED: E3 ubiquiti ( 841) 220 51.2 1.1e-05
XP_011528738 (OMIM: 612062) PREDICTED: E3 ubiquiti ( 841) 220 51.2 1.1e-05
XP_011528740 (OMIM: 612062) PREDICTED: E3 ubiquiti ( 841) 220 51.2 1.1e-05
NP_001193927 (OMIM: 612062) E3 ubiquitin-protein l ( 936) 220 51.2 1.1e-05
NP_001292473 (OMIM: 612482,617108) E3 ubiquitin-pr ( 783) 205 48.4 6.6e-05
NP_060233 (OMIM: 612482,617108) E3 ubiquitin-prote ( 783) 205 48.4 6.6e-05
XP_011523257 (OMIM: 612482,617108) PREDICTED: E3 u ( 869) 205 48.5 7.1e-05
XP_016880289 (OMIM: 612482,617108) PREDICTED: E3 u ( 869) 205 48.5 7.1e-05
NP_001127809 (OMIM: 612489) RING finger protein 24 ( 148) 192 45.4 0.0001
NP_009150 (OMIM: 612489) RING finger protein 24 is ( 148) 192 45.4 0.0001
NP_001308678 (OMIM: 612489) RING finger protein 24 ( 148) 192 45.4 0.0001
XP_011527448 (OMIM: 612489) PREDICTED: RING finger ( 163) 192 45.5 0.00011
XP_016883109 (OMIM: 612489) PREDICTED: RING finger ( 169) 192 45.5 0.00011
NP_001127810 (OMIM: 612489) RING finger protein 24 ( 169) 192 45.5 0.00011
XP_016883110 (OMIM: 612489) PREDICTED: RING finger ( 169) 192 45.5 0.00011
XP_011527447 (OMIM: 612489) PREDICTED: RING finger ( 169) 192 45.5 0.00011
XP_016877829 (OMIM: 605840) PREDICTED: E3 ubiquiti ( 993) 202 48.0 0.00011
XP_016877830 (OMIM: 605840) PREDICTED: E3 ubiquiti ( 993) 202 48.0 0.00011
>>NP_078815 (OMIM: 300439) E3 ubiquitin-protein ligase R (402 aa)
initn: 1036 init1: 628 opt: 1068 Z-score: 1056.3 bits: 204.2 E(85289): 4.2e-52
Smith-Waterman score: 1072; 44.7% identity (74.5% similar) in 380 aa overlap (11-374:5-378)
10 20 30 40 50
pF1KE3 MHLLKVGTWRNNTASSWLMK-FSVLWLVSQNCCRASVVWMAYMNISFHVGNHVLSELGET
: .. ::. :. : .. . .. : ..:.: ...:.. : :
NP_078 MNQENRSSFFWLLVIFTFLLKITASFSMSAYVTVTYYN---ETSNYTAIETCEC
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 GVFGRSSTLKRVAGVIVPPEGKIQNACNPNTIFSRSKYSETWLALIERGGCTFTQKIKVA
::.: .: . . ::. :... .::. :: :: .: . :.::::::.:::..::..:
NP_078 GVYGLASPVANAMGVVGIPKNNNYQACDHNTEFSNTK--KPWIALIERGNCTFSEKIQTA
60 70 80 90 100
120 130 140 150 160 170
pF1KE3 TEKGASGVIIYNVPGTGNQVFPMFHQAFEDVVVVMIGNLKGTEIFHLIKKGVLITAVVEV
...:..:.:::.: ::::.. : . . :.:..::::::::.:.. :..:. .: :.::
NP_078 GRRNADAVVIYNAPETGNQTIQMANFGAVDIVAIMIGNLKGTKILQSIQRGIQVTMVIEV
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE3 GRKHIIWMNHYL-----VSFVIVTTATLAYFIFYHIHRLCLARIQNRRWQRLTTDLQNTF
:.:: :.::: ::: :.:.::..::::: .:: :: :.:. ..: .: ....
NP_078 GKKHGPWVNHYSIFFVSVSFFIITAATVGYFIFYSARRLRNARAQSRKQRQLKADAKKAI
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE3 GQLQLRVVKEGDEEINPNGDSCVICFERYKPNDIVRILTCKHFFHKNCIDPWILPHGTCP
:.::::..:.::.::.:.::::..:.: :::::.::::::.:.:::.:.:::.: : :::
NP_078 GRLQLRTLKQGDKEIGPDGDSCAVCIELYKPNDLVRILTCNHIFHKTCVDPWLLEHRTCP
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE3 ICKCDILKVLGIQVVVENGTEPLQVLMSNELPETLSPSEEETNNEVSPAGTSDKVIHVEE
.:::::::.:::.: ::.:. ::: .:::. .. : ::.. .:.. .: .. : ..:
NP_078 MCKCDILKALGIEVDVEDGSVSLQVPVSNEISNSASSHEEDNRSETASSGYAS-VQGTDE
290 300 310 320 330 340
360 370
pF1KE3 NPT-----SQNNDIQ-----PHSVVEDVHPSP
: : :...: .::. :: :
NP_078 PPLEEHVQSTNESLQLVNHEANSVAVDVIPHVDNPTFEEDETPNQETAVREIKS
350 360 370 380 390 400
>>NP_919445 (OMIM: 300439) E3 ubiquitin-protein ligase R (428 aa)
initn: 1204 init1: 628 opt: 991 Z-score: 980.7 bits: 190.3 E(85289): 6.9e-48
Smith-Waterman score: 1170; 50.1% identity (76.8% similar) in 367 aa overlap (34-374:39-404)
10 20 30 40 50
pF1KE3 LKVGTWRNNTASSWLMKFSVLWLVSQNCCRASVVWMAYMNISF---HVG-NHVLSELGET
: .:: ::.:.:. :.: :... ::.:
NP_919 VSCRGGCGFSRLLAWCFLLALSPQAPGSRGAEAVWTAYLNVSWRVPHTGVNRTVWELSEE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 GVFGRSSTLKRVAGVIVPPEGK-IQNACNPNTIFSR-----SKYSETWLALIERGG-CTF
::.:..: :. ::::.:::.: :::::.: :. : . .:::::.::: :::
NP_919 GVYGQDSPLEPVAGVLVPPDGPGALNACNPHTNFTVPTVWGSTVQVSWLALIQRGGGCTF
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 TQKIKVATEKGASGVIIYNVPGTGNQVFPMFHQAFEDVVVVMIGNLKGTEIFHLIKKGVL
..::..: :.::::..:.: ::: :.:.:: : . :.:..::::::::.:.. :..:.
NP_919 ADKIHLAYERGASGAVIFNFPGTRNEVIPMSHPGAVDIVAIMIGNLKGTKILQSIQRGIQ
130 140 150 160 170 180
180 190 200 210 220
pF1KE3 ITAVVEVGRKHIIWMNHYL-----VSFVIVTTATLAYFIFYHIHRLCLARIQNRRWQRLT
.: :.:::.:: :.::: ::: :.:.::..::::: .:: :: :.:. ..:
NP_919 VTMVIEVGKKHGPWVNHYSIFFVSVSFFIITAATVGYFIFYSARRLRNARAQSRKQRQLK
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE3 TDLQNTFGQLQLRVVKEGDEEINPNGDSCVICFERYKPNDIVRILTCKHFFHKNCIDPWI
.: ....:.::::..:.::.::.:.::::..:.: :::::.::::::.:.:::.:.:::.
NP_919 ADAKKAIGRLQLRTLKQGDKEIGPDGDSCAVCIELYKPNDLVRILTCNHIFHKTCVDPWL
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE3 LPHGTCPICKCDILKVLGIQVVVENGTEPLQVLMSNELPETLSPSEEETNNEVSPAGTSD
: : :::.:::::::.:::.: ::.:. ::: .:::. .. : ::.. .:.. .: ..
NP_919 LEHRTCPMCKCDILKALGIEVDVEDGSVSLQVPVSNEISNSASSHEEDNRSETASSGYAS
310 320 330 340 350 360
350 360 370
pF1KE3 KVIHVEENPT-----SQNNDIQ-----PHSVVEDVHPSP
: ..: : : :...: .::. :: :
NP_919 -VQGTDEPPLEEHVQSTNESLQLVNHEANSVAVDVIPHVDNPTFEEDETPNQETAVREIK
370 380 390 400 410 420
NP_919 S
>>NP_001307292 (OMIM: 610431) E3 ubiquitin-protein ligas (315 aa)
initn: 234 init1: 171 opt: 270 Z-score: 277.8 bits: 59.8 E(85289): 9.8e-09
Smith-Waterman score: 288; 27.8% identity (60.9% similar) in 248 aa overlap (61-297:9-237)
40 50 60 70 80 90
pF1KE3 CCRASVVWMAYMNISFHVGNHVLSELGETGVFGRSSTLKRVAGVIVPPEGKIQNACNPNT
.:: . . . . : .: :.. .:::.: .
NP_001 MDFADLPALFGATLSQEGLQGFLV--EAHPDNACSPIA
10 20 30
100 110 120 130 140
pF1KE3 IFSRSKYSET-WLALIERGGCTFTQKIKVATEKGASGVIIYNVPGTGNQVFPMFHQAFE-
. . . ..::..: :.: :. : . : ......:: ..:... : .. :
NP_001 PPPPAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNV--NSNELLNMVWNSEEI
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE3 --DVVV--VMIGNLKGTEIFHLI---KKGVLITAVVEVGRKHIIWMNHYLVSFV-IVTTA
.. . :.::. ...: .. . .::. . : . . . ...::. :. ::
NP_001 QQQIWIPSVFIGE-RSSEYLRALFVYEKGARVLLVPD----NTFPLGYYLIPFTGIVGLL
100 110 120 130 140
210 220 230 240 250 260
pF1KE3 TLAYFIFYHIHRLCLARIQNRRWQRLTTDLQNTFGQLQLRVVKEGDEEINPNGDSCVICF
.::. . : : : ::.:. :: .: . . ::. . : . . . : :.::.
NP_001 VLAMGAVM-IAR-C---IQHRK--RLQ---RNRLTKEQLKQIPTHDYQKGDQYDVCAICL
150 160 170 180 190
270 280 290 300 310
pF1KE3 ERYKPNDIVRILTCKHFFHKNCIDPWILP-HGTCPICKCDILKVLGIQVVVENGTEPLQV
..:. .: .:.: : : .:. :.:::. . ::::::
NP_001 DEYEDGDKLRVLPCAHAYHSRCVDPWLTQTRKTCPICKQPVHRGPGDEDQEEETQGQEEG
200 210 220 230 240 250
320 330 340 350 360 370
pF1KE3 LMSNELPETLSPSEEETNNEVSPAGTSDKVIHVEENPTSQNNDIQPHSVVEDVHPSP
NP_001 DEGEPRDHPASERTPLLGSSPTLPTSFGSLAPAPLVFPGPSTDPPLSPPSSPVILV
260 270 280 290 300 310
>>NP_001307294 (OMIM: 610431) E3 ubiquitin-protein ligas (315 aa)
initn: 234 init1: 171 opt: 270 Z-score: 277.8 bits: 59.8 E(85289): 9.8e-09
Smith-Waterman score: 288; 27.8% identity (60.9% similar) in 248 aa overlap (61-297:9-237)
40 50 60 70 80 90
pF1KE3 CCRASVVWMAYMNISFHVGNHVLSELGETGVFGRSSTLKRVAGVIVPPEGKIQNACNPNT
.:: . . . . : .: :.. .:::.: .
NP_001 MDFADLPALFGATLSQEGLQGFLV--EAHPDNACSPIA
10 20 30
100 110 120 130 140
pF1KE3 IFSRSKYSET-WLALIERGGCTFTQKIKVATEKGASGVIIYNVPGTGNQVFPMFHQAFE-
. . . ..::..: :.: :. : . : ......:: ..:... : .. :
NP_001 PPPPAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNV--NSNELLNMVWNSEEI
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE3 --DVVV--VMIGNLKGTEIFHLI---KKGVLITAVVEVGRKHIIWMNHYLVSFV-IVTTA
.. . :.::. ...: .. . .::. . : . . . ...::. :. ::
NP_001 QQQIWIPSVFIGE-RSSEYLRALFVYEKGARVLLVPD----NTFPLGYYLIPFTGIVGLL
100 110 120 130 140
210 220 230 240 250 260
pF1KE3 TLAYFIFYHIHRLCLARIQNRRWQRLTTDLQNTFGQLQLRVVKEGDEEINPNGDSCVICF
.::. . : : : ::.:. :: .: . . ::. . : . . . : :.::.
NP_001 VLAMGAVM-IAR-C---IQHRK--RLQ---RNRLTKEQLKQIPTHDYQKGDQYDVCAICL
150 160 170 180 190
270 280 290 300 310
pF1KE3 ERYKPNDIVRILTCKHFFHKNCIDPWILP-HGTCPICKCDILKVLGIQVVVENGTEPLQV
..:. .: .:.: : : .:. :.:::. . ::::::
NP_001 DEYEDGDKLRVLPCAHAYHSRCVDPWLTQTRKTCPICKQPVHRGPGDEDQEEETQGQEEG
200 210 220 230 240 250
320 330 340 350 360 370
pF1KE3 LMSNELPETLSPSEEETNNEVSPAGTSDKVIHVEENPTSQNNDIQPHSVVEDVHPSP
NP_001 DEGEPRDHPASERTPLLGSSPTLPTSFGSLAPAPLVFPGPSTDPPLSPPSSPVILV
260 270 280 290 300 310
>>NP_001307291 (OMIM: 610431) E3 ubiquitin-protein ligas (315 aa)
initn: 234 init1: 171 opt: 270 Z-score: 277.8 bits: 59.8 E(85289): 9.8e-09
Smith-Waterman score: 288; 27.8% identity (60.9% similar) in 248 aa overlap (61-297:9-237)
40 50 60 70 80 90
pF1KE3 CCRASVVWMAYMNISFHVGNHVLSELGETGVFGRSSTLKRVAGVIVPPEGKIQNACNPNT
.:: . . . . : .: :.. .:::.: .
NP_001 MDFADLPALFGATLSQEGLQGFLV--EAHPDNACSPIA
10 20 30
100 110 120 130 140
pF1KE3 IFSRSKYSET-WLALIERGGCTFTQKIKVATEKGASGVIIYNVPGTGNQVFPMFHQAFE-
. . . ..::..: :.: :. : . : ......:: ..:... : .. :
NP_001 PPPPAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNV--NSNELLNMVWNSEEI
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE3 --DVVV--VMIGNLKGTEIFHLI---KKGVLITAVVEVGRKHIIWMNHYLVSFV-IVTTA
.. . :.::. ...: .. . .::. . : . . . ...::. :. ::
NP_001 QQQIWIPSVFIGE-RSSEYLRALFVYEKGARVLLVPD----NTFPLGYYLIPFTGIVGLL
100 110 120 130 140
210 220 230 240 250 260
pF1KE3 TLAYFIFYHIHRLCLARIQNRRWQRLTTDLQNTFGQLQLRVVKEGDEEINPNGDSCVICF
.::. . : : : ::.:. :: .: . . ::. . : . . . : :.::.
NP_001 VLAMGAVM-IAR-C---IQHRK--RLQ---RNRLTKEQLKQIPTHDYQKGDQYDVCAICL
150 160 170 180 190
270 280 290 300 310
pF1KE3 ERYKPNDIVRILTCKHFFHKNCIDPWILP-HGTCPICKCDILKVLGIQVVVENGTEPLQV
..:. .: .:.: : : .:. :.:::. . ::::::
NP_001 DEYEDGDKLRVLPCAHAYHSRCVDPWLTQTRKTCPICKQPVHRGPGDEDQEEETQGQEEG
200 210 220 230 240 250
320 330 340 350 360 370
pF1KE3 LMSNELPETLSPSEEETNNEVSPAGTSDKVIHVEENPTSQNNDIQPHSVVEDVHPSP
NP_001 DEGEPRDHPASERTPLLGSSPTLPTSFGSLAPAPLVFPGPSTDPPLSPPSSPVILV
260 270 280 290 300 310
>>NP_001307293 (OMIM: 610431) E3 ubiquitin-protein ligas (315 aa)
initn: 234 init1: 171 opt: 270 Z-score: 277.8 bits: 59.8 E(85289): 9.8e-09
Smith-Waterman score: 288; 27.8% identity (60.9% similar) in 248 aa overlap (61-297:9-237)
40 50 60 70 80 90
pF1KE3 CCRASVVWMAYMNISFHVGNHVLSELGETGVFGRSSTLKRVAGVIVPPEGKIQNACNPNT
.:: . . . . : .: :.. .:::.: .
NP_001 MDFADLPALFGATLSQEGLQGFLV--EAHPDNACSPIA
10 20 30
100 110 120 130 140
pF1KE3 IFSRSKYSET-WLALIERGGCTFTQKIKVATEKGASGVIIYNVPGTGNQVFPMFHQAFE-
. . . ..::..: :.: :. : . : ......:: ..:... : .. :
NP_001 PPPPAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNV--NSNELLNMVWNSEEI
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE3 --DVVV--VMIGNLKGTEIFHLI---KKGVLITAVVEVGRKHIIWMNHYLVSFV-IVTTA
.. . :.::. ...: .. . .::. . : . . . ...::. :. ::
NP_001 QQQIWIPSVFIGE-RSSEYLRALFVYEKGARVLLVPD----NTFPLGYYLIPFTGIVGLL
100 110 120 130 140
210 220 230 240 250 260
pF1KE3 TLAYFIFYHIHRLCLARIQNRRWQRLTTDLQNTFGQLQLRVVKEGDEEINPNGDSCVICF
.::. . : : : ::.:. :: .: . . ::. . : . . . : :.::.
NP_001 VLAMGAVM-IAR-C---IQHRK--RLQ---RNRLTKEQLKQIPTHDYQKGDQYDVCAICL
150 160 170 180 190
270 280 290 300 310
pF1KE3 ERYKPNDIVRILTCKHFFHKNCIDPWILP-HGTCPICKCDILKVLGIQVVVENGTEPLQV
..:. .: .:.: : : .:. :.:::. . ::::::
NP_001 DEYEDGDKLRVLPCAHAYHSRCVDPWLTQTRKTCPICKQPVHRGPGDEDQEEETQGQEEG
200 210 220 230 240 250
320 330 340 350 360 370
pF1KE3 LMSNELPETLSPSEEETNNEVSPAGTSDKVIHVEENPTSQNNDIQPHSVVEDVHPSP
NP_001 DEGEPRDHPASERTPLLGSSPTLPTSFGSLAPAPLVFPGPSTDPPLSPPSSPVILV
260 270 280 290 300 310
>>NP_001307287 (OMIM: 610431) E3 ubiquitin-protein ligas (350 aa)
initn: 234 init1: 171 opt: 270 Z-score: 277.2 bits: 59.9 E(85289): 1.1e-08
Smith-Waterman score: 288; 27.8% identity (60.9% similar) in 248 aa overlap (61-297:44-272)
40 50 60 70 80 90
pF1KE3 CCRASVVWMAYMNISFHVGNHVLSELGETGVFGRSSTLKRVAGVIVPPEGKIQNACNPNT
.:: . . . . : .: :.. .:::.: .
NP_001 AVLWGAAPTRGLIRATSDHNASMDFADLPALFGATLSQEGLQGFLV--EAHPDNACSPIA
20 30 40 50 60 70
100 110 120 130 140
pF1KE3 IFSRSKYSET-WLALIERGGCTFTQKIKVATEKGASGVIIYNVPGTGNQVFPMFHQAFE-
. . . ..::..: :.: :. : . : ......:: ..:... : .. :
NP_001 PPPPAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNV--NSNELLNMVWNSEEI
80 90 100 110 120
150 160 170 180 190 200
pF1KE3 --DVVV--VMIGNLKGTEIFHLI---KKGVLITAVVEVGRKHIIWMNHYLVSFV-IVTTA
.. . :.::. ...: .. . .::. . : . . . ...::. :. ::
NP_001 QQQIWIPSVFIGE-RSSEYLRALFVYEKGARVLLVPD----NTFPLGYYLIPFTGIVGLL
130 140 150 160 170 180
210 220 230 240 250 260
pF1KE3 TLAYFIFYHIHRLCLARIQNRRWQRLTTDLQNTFGQLQLRVVKEGDEEINPNGDSCVICF
.::. . : : : ::.:. :: .: . . ::. . : . . . : :.::.
NP_001 VLAMGAVM-IAR-C---IQHRK--RLQ---RNRLTKEQLKQIPTHDYQKGDQYDVCAICL
190 200 210 220 230
270 280 290 300 310
pF1KE3 ERYKPNDIVRILTCKHFFHKNCIDPWILP-HGTCPICKCDILKVLGIQVVVENGTEPLQV
..:. .: .:.: : : .:. :.:::. . ::::::
NP_001 DEYEDGDKLRVLPCAHAYHSRCVDPWLTQTRKTCPICKQPVHRGPGDEDQEEETQGQEEG
240 250 260 270 280 290
320 330 340 350 360 370
pF1KE3 LMSNELPETLSPSEEETNNEVSPAGTSDKVIHVEENPTSQNNDIQPHSVVEDVHPSP
NP_001 DEGEPRDHPASERTPLLGSSPTLPTSFGSLAPAPLVFPGPSTDPPLSPPSSPVILV
300 310 320 330 340 350
>>NP_056343 (OMIM: 610431) E3 ubiquitin-protein ligase R (350 aa)
initn: 234 init1: 171 opt: 270 Z-score: 277.2 bits: 59.9 E(85289): 1.1e-08
Smith-Waterman score: 288; 27.8% identity (60.9% similar) in 248 aa overlap (61-297:44-272)
40 50 60 70 80 90
pF1KE3 CCRASVVWMAYMNISFHVGNHVLSELGETGVFGRSSTLKRVAGVIVPPEGKIQNACNPNT
.:: . . . . : .: :.. .:::.: .
NP_056 AVLWGAAPTRGLIRATSDHNASMDFADLPALFGATLSQEGLQGFLV--EAHPDNACSPIA
20 30 40 50 60 70
100 110 120 130 140
pF1KE3 IFSRSKYSET-WLALIERGGCTFTQKIKVATEKGASGVIIYNVPGTGNQVFPMFHQAFE-
. . . ..::..: :.: :. : . : ......:: ..:... : .. :
NP_056 PPPPAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNV--NSNELLNMVWNSEEI
80 90 100 110 120
150 160 170 180 190 200
pF1KE3 --DVVV--VMIGNLKGTEIFHLI---KKGVLITAVVEVGRKHIIWMNHYLVSFV-IVTTA
.. . :.::. ...: .. . .::. . : . . . ...::. :. ::
NP_056 QQQIWIPSVFIGE-RSSEYLRALFVYEKGARVLLVPD----NTFPLGYYLIPFTGIVGLL
130 140 150 160 170 180
210 220 230 240 250 260
pF1KE3 TLAYFIFYHIHRLCLARIQNRRWQRLTTDLQNTFGQLQLRVVKEGDEEINPNGDSCVICF
.::. . : : : ::.:. :: .: . . ::. . : . . . : :.::.
NP_056 VLAMGAVM-IAR-C---IQHRK--RLQ---RNRLTKEQLKQIPTHDYQKGDQYDVCAICL
190 200 210 220 230
270 280 290 300 310
pF1KE3 ERYKPNDIVRILTCKHFFHKNCIDPWILP-HGTCPICKCDILKVLGIQVVVENGTEPLQV
..:. .: .:.: : : .:. :.:::. . ::::::
NP_056 DEYEDGDKLRVLPCAHAYHSRCVDPWLTQTRKTCPICKQPVHRGPGDEDQEEETQGQEEG
240 250 260 270 280 290
320 330 340 350 360 370
pF1KE3 LMSNELPETLSPSEEETNNEVSPAGTSDKVIHVEENPTSQNNDIQPHSVVEDVHPSP
NP_056 DEGEPRDHPASERTPLLGSSPTLPTSFGSLAPAPLVFPGPSTDPPLSPPSSPVILV
300 310 320 330 340 350
>>NP_001307290 (OMIM: 610431) E3 ubiquitin-protein ligas (350 aa)
initn: 234 init1: 171 opt: 270 Z-score: 277.2 bits: 59.9 E(85289): 1.1e-08
Smith-Waterman score: 288; 27.8% identity (60.9% similar) in 248 aa overlap (61-297:44-272)
40 50 60 70 80 90
pF1KE3 CCRASVVWMAYMNISFHVGNHVLSELGETGVFGRSSTLKRVAGVIVPPEGKIQNACNPNT
.:: . . . . : .: :.. .:::.: .
NP_001 AVLWGAAPTRGLIRATSDHNASMDFADLPALFGATLSQEGLQGFLV--EAHPDNACSPIA
20 30 40 50 60 70
100 110 120 130 140
pF1KE3 IFSRSKYSET-WLALIERGGCTFTQKIKVATEKGASGVIIYNVPGTGNQVFPMFHQAFE-
. . . ..::..: :.: :. : . : ......:: ..:... : .. :
NP_001 PPPPAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNV--NSNELLNMVWNSEEI
80 90 100 110 120
150 160 170 180 190 200
pF1KE3 --DVVV--VMIGNLKGTEIFHLI---KKGVLITAVVEVGRKHIIWMNHYLVSFV-IVTTA
.. . :.::. ...: .. . .::. . : . . . ...::. :. ::
NP_001 QQQIWIPSVFIGE-RSSEYLRALFVYEKGARVLLVPD----NTFPLGYYLIPFTGIVGLL
130 140 150 160 170 180
210 220 230 240 250 260
pF1KE3 TLAYFIFYHIHRLCLARIQNRRWQRLTTDLQNTFGQLQLRVVKEGDEEINPNGDSCVICF
.::. . : : : ::.:. :: .: . . ::. . : . . . : :.::.
NP_001 VLAMGAVM-IAR-C---IQHRK--RLQ---RNRLTKEQLKQIPTHDYQKGDQYDVCAICL
190 200 210 220 230
270 280 290 300 310
pF1KE3 ERYKPNDIVRILTCKHFFHKNCIDPWILP-HGTCPICKCDILKVLGIQVVVENGTEPLQV
..:. .: .:.: : : .:. :.:::. . ::::::
NP_001 DEYEDGDKLRVLPCAHAYHSRCVDPWLTQTRKTCPICKQPVHRGPGDEDQEEETQGQEEG
240 250 260 270 280 290
320 330 340 350 360 370
pF1KE3 LMSNELPETLSPSEEETNNEVSPAGTSDKVIHVEENPTSQNNDIQPHSVVEDVHPSP
NP_001 DEGEPRDHPASERTPLLGSSPTLPTSFGSLAPAPLVFPGPSTDPPLSPPSSPVILV
300 310 320 330 340 350
>>NP_001307289 (OMIM: 610431) E3 ubiquitin-protein ligas (350 aa)
initn: 234 init1: 171 opt: 270 Z-score: 277.2 bits: 59.9 E(85289): 1.1e-08
Smith-Waterman score: 288; 27.8% identity (60.9% similar) in 248 aa overlap (61-297:44-272)
40 50 60 70 80 90
pF1KE3 CCRASVVWMAYMNISFHVGNHVLSELGETGVFGRSSTLKRVAGVIVPPEGKIQNACNPNT
.:: . . . . : .: :.. .:::.: .
NP_001 AVLWGAAPTRGLIRATSDHNASMDFADLPALFGATLSQEGLQGFLV--EAHPDNACSPIA
20 30 40 50 60 70
100 110 120 130 140
pF1KE3 IFSRSKYSET-WLALIERGGCTFTQKIKVATEKGASGVIIYNVPGTGNQVFPMFHQAFE-
. . . ..::..: :.: :. : . : ......:: ..:... : .. :
NP_001 PPPPAPVNGSVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNV--NSNELLNMVWNSEEI
80 90 100 110 120
150 160 170 180 190 200
pF1KE3 --DVVV--VMIGNLKGTEIFHLI---KKGVLITAVVEVGRKHIIWMNHYLVSFV-IVTTA
.. . :.::. ...: .. . .::. . : . . . ...::. :. ::
NP_001 QQQIWIPSVFIGE-RSSEYLRALFVYEKGARVLLVPD----NTFPLGYYLIPFTGIVGLL
130 140 150 160 170 180
210 220 230 240 250 260
pF1KE3 TLAYFIFYHIHRLCLARIQNRRWQRLTTDLQNTFGQLQLRVVKEGDEEINPNGDSCVICF
.::. . : : : ::.:. :: .: . . ::. . : . . . : :.::.
NP_001 VLAMGAVM-IAR-C---IQHRK--RLQ---RNRLTKEQLKQIPTHDYQKGDQYDVCAICL
190 200 210 220 230
270 280 290 300 310
pF1KE3 ERYKPNDIVRILTCKHFFHKNCIDPWILP-HGTCPICKCDILKVLGIQVVVENGTEPLQV
..:. .: .:.: : : .:. :.:::. . ::::::
NP_001 DEYEDGDKLRVLPCAHAYHSRCVDPWLTQTRKTCPICKQPVHRGPGDEDQEEETQGQEEG
240 250 260 270 280 290
320 330 340 350 360 370
pF1KE3 LMSNELPETLSPSEEETNNEVSPAGTSDKVIHVEENPTSQNNDIQPHSVVEDVHPSP
NP_001 DEGEPRDHPASERTPLLGSSPTLPTSFGSLAPAPLVFPGPSTDPPLSPPSSPVILV
300 310 320 330 340 350
376 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 04:50:05 2016 done: Sun Nov 6 04:50:06 2016
Total Scan time: 6.420 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]