Result of FASTA (ccds) for
pFN21AE3147
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3147, 360 aa
1>>>pF1KE3147 360 - 360 aa - 360 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4706+/-0.00087; mu= 14.9507+/- 0.052
mean_var=64.1092+/-13.026, 0's: 0 Z-trim(105.8): 24 B-trim: 0 in 0/49
Lambda= 0.160182
statistics sampled from 8588 (8597) to 8588 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.648), E-opt: 0.2 (0.264), width: 16
Scan time: 2.680
The best scores are: opt bits E(32554)
CCDS8806.1 LETMD1 gene_id:25875|Hs108|chr12 ( 360) 2447 574.3 5.4e-164
CCDS58231.1 LETMD1 gene_id:25875|Hs108|chr12 ( 373) 1550 367.0 1.4e-101
CCDS73469.1 LETMD1 gene_id:25875|Hs108|chr12 ( 236) 908 218.6 4.3e-57
CCDS69466.1 LETM2 gene_id:137994|Hs108|chr8 ( 491) 278 73.1 5.5e-13
CCDS56534.1 LETM2 gene_id:137994|Hs108|chr8 ( 444) 273 72.0 1.1e-12
CCDS3355.1 LETM1 gene_id:3954|Hs108|chr4 ( 739) 263 69.7 8.7e-12
>>CCDS8806.1 LETMD1 gene_id:25875|Hs108|chr12 (360 aa)
initn: 2447 init1: 2447 opt: 2447 Z-score: 3057.6 bits: 574.3 E(32554): 5.4e-164
Smith-Waterman score: 2447; 100.0% identity (100.0% similar) in 360 aa overlap (1-360:1-360)
10 20 30 40 50 60
pF1KE3 MALSRVCWARSAVWGSAVTPGHFVTRRLQLGRSGLAWGAPRSSKLHLSPKADVKNLMSYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 MALSRVCWARSAVWGSAVTPGHFVTRRLQLGRSGLAWGAPRSSKLHLSPKADVKNLMSYV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VTKTKAINGKYHRFLGRHFPRFYVLYTIFMKGLQMLWADAKKARRIKTNMWKHNIKFHQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 VTKTKAINGKYHRFLGRHFPRFYVLYTIFMKGLQMLWADAKKARRIKTNMWKHNIKFHQL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 PYREMEHLRQFRQDVTKCLFLGIISIPPFANYLVFLLMYLFPRQLLIRHFWTPKQQTDFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 PYREMEHLRQFRQDVTKCLFLGIISIPPFANYLVFLLMYLFPRQLLIRHFWTPKQQTDFL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 DIYHAFRKQSHPEIISYLEKVIPLISDAGLRWRLTDLCTKIQRGTHPAIHDILALRECFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 DIYHAFRKQSHPEIISYLEKVIPLISDAGLRWRLTDLCTKIQRGTHPAIHDILALRECFS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 NHPLGMNQLQALHVKALSRAMLLTSYLPPPLLRHRLKTHTTVIHQLDKALAKLGIGQLTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 NHPLGMNQLQALHVKALSRAMLLTSYLPPPLLRHRLKTHTTVIHQLDKALAKLGIGQLTA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 QEVKSACYLRGLNSTHIGEDRCRTWLGEWLQISCSLKEAELSLLLHNVVLLSTNYLGTRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 QEVKSACYLRGLNSTHIGEDRCRTWLGEWLQISCSLKEAELSLLLHNVVLLSTNYLGTRR
310 320 330 340 350 360
>>CCDS58231.1 LETMD1 gene_id:25875|Hs108|chr12 (373 aa)
initn: 1550 init1: 1550 opt: 1550 Z-score: 1937.1 bits: 367.0 E(32554): 1.4e-101
Smith-Waterman score: 2411; 96.5% identity (96.5% similar) in 373 aa overlap (1-360:1-373)
10 20 30 40 50 60
pF1KE3 MALSRVCWARSAVWGSAVTPGHFVTRRLQLGRSGLAWGAPRSSKLHLSPKADVKNLMSYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 MALSRVCWARSAVWGSAVTPGHFVTRRLQLGRSGLAWGAPRSSKLHLSPKADVKNLMSYV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VTKTKAINGKYHRFLGRHFPRFYVLYTIFMKGLQMLWADAKKARRIKTNMWKHNIKFHQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 VTKTKAINGKYHRFLGRHFPRFYVLYTIFMKGLQMLWADAKKARRIKTNMWKHNIKFHQL
70 80 90 100 110 120
130 140 150 160
pF1KE3 PYREMEHLRQ-------------FRQDVTKCLFLGIISIPPFANYLVFLLMYLFPRQLLI
:::::::::: :::::::::::::::::::::::::::::::::::::
CCDS58 PYREMEHLRQVWARGRYPEVHGEFRQDVTKCLFLGIISIPPFANYLVFLLMYLFPRQLLI
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE3 RHFWTPKQQTDFLDIYHAFRKQSHPEIISYLEKVIPLISDAGLRWRLTDLCTKIQRGTHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 RHFWTPKQQTDFLDIYHAFRKQSHPEIISYLEKVIPLISDAGLRWRLTDLCTKIQRGTHP
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE3 AIHDILALRECFSNHPLGMNQLQALHVKALSRAMLLTSYLPPPLLRHRLKTHTTVIHQLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 AIHDILALRECFSNHPLGMNQLQALHVKALSRAMLLTSYLPPPLLRHRLKTHTTVIHQLD
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE3 KALAKLGIGQLTAQEVKSACYLRGLNSTHIGEDRCRTWLGEWLQISCSLKEAELSLLLHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 KALAKLGIGQLTAQEVKSACYLRGLNSTHIGEDRCRTWLGEWLQISCSLKEAELSLLLHN
310 320 330 340 350 360
350 360
pF1KE3 VVLLSTNYLGTRR
:::::::::::::
CCDS58 VVLLSTNYLGTRR
370
>>CCDS73469.1 LETMD1 gene_id:25875|Hs108|chr12 (236 aa)
initn: 926 init1: 899 opt: 908 Z-score: 1138.4 bits: 218.6 E(32554): 4.3e-57
Smith-Waterman score: 1331; 65.6% identity (65.6% similar) in 360 aa overlap (1-360:1-236)
10 20 30 40 50 60
pF1KE3 MALSRVCWARSAVWGSAVTPGHFVTRRLQLGRSGLAWGAPRSSKLHLSPKADVKNLMSYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 MALSRVCWARSAVWGSAVTPGHFVTRRLQLGRSGLAWGAPRSSKLHLSPKADVKNLMSYV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VTKTKAINGKYHRFLGRHFPRFYVLYTIFMKGLQMLWADAKKARRIKTNMWKHNIKFHQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 VTKTKAINGKYHRFLGRHFPRFYVLYTIFMKGLQMLWADAKKARRIKTNMWKHNIKFHQL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 PYREMEHLRQFRQDVTKCLFLGIISIPPFANYLVFLLMYLFPRQLLIRHFWTPKQQTDFL
::::::::::
CCDS73 PYREMEHLRQ--------------------------------------------------
130
190 200 210 220 230 240
pF1KE3 DIYHAFRKQSHPEIISYLEKVIPLISDAGLRWRLTDLCTKIQRGTHPAIHDILALRECFS
CCDS73 ------------------------------------------------------------
250 260 270 280 290 300
pF1KE3 NHPLGMNQLQALHVKALSRAMLLTSYLPPPLLRHRLKTHTTVIHQLDKALAKLGIGQLTA
::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 --------------KALSRAMLLTSYLPPPLLRHRLKTHTTVIHQLDKALAKLGIGQLTA
140 150 160 170
310 320 330 340 350 360
pF1KE3 QEVKSACYLRGLNSTHIGEDRCRTWLGEWLQISCSLKEAELSLLLHNVVLLSTNYLGTRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 QEVKSACYLRGLNSTHIGEDRCRTWLGEWLQISCSLKEAELSLLLHNVVLLSTNYLGTRR
180 190 200 210 220 230
>>CCDS69466.1 LETM2 gene_id:137994|Hs108|chr8 (491 aa)
initn: 236 init1: 139 opt: 278 Z-score: 346.6 bits: 73.1 E(32554): 5.5e-13
Smith-Waterman score: 278; 23.6% identity (54.8% similar) in 356 aa overlap (3-345:43-384)
10 20
pF1KE3 MALSRVCWA--RSAVWGSAVTPGHFV----TR
:...: .: ... ::. : ::
CCDS69 ARTRFPSHFVHPTCSSYSPSCAFLHLPDSHLNKTCMKNYESKKYSDPSQPGNTVLHPGTR
20 30 40 50 60 70
30 40 50 60 70 80
pF1KE3 RLQLGRSGLAWGAPRSSKLHLSPKADVKNLMSYVVTKTKAINGKYHRFLGRHFPRFYVLY
.: ... : .: .: . .. : .:: ... : :.. : ..
CCDS69 LIQKLHTSTCWLQEVPGKPQLEQATKHPQVTSPQATKETGMEIKE----GKQSYRQKIMD
80 90 100 110 120
90 100 110 120 130 140
pF1KE3 TI--FMKGLQMLWADAKKARRIKTNMWKHNIKFHQLPYREMEHLRQFRQDVTKCLFLGII
. ...:. .:: ::: : :. .:. .. . : :: ..: . : . . . ..
CCDS69 ELKYYYNGFYLLWIDAKVAARM---VWRL-LHGQVLTRRERRRLLRTCVDFFRLVPFMVF
130 140 150 160 170 180
150 160 170 180 190 200
pF1KE3 SIPPFANYLVFLLMYLFPRQLLIRHFWTP----KQQTDFLDIYHAFRKQSHPEIISYLEK
: :: ..:. ... ::: ..: : . ..: . . . : . . . ..
CCDS69 LIVPFMEFLLPVFLKLFP-EMLPSTFESESKKEEKQKKKMAVKLELAKFLQETMTEMARR
190 200 210 220 230 240
210 220 230 240 250 260
pF1KE3 VIPLISDAGLRWRLTDLCTKIQRGTHPAIHDILALRECFSNHPLGMNQLQALHVKALSRA
..::. . :.. ..: : .:. ..:. . . : .. :....:. .. :: .
CCDS69 NRAKMGDASTQ--LSSYVKQVQTGHKPSTKEIVRFSKLFEDQ-LALEHLDRPQLVALCKL
250 260 270 280 290 300
270 280 290 300 310 320
pF1KE3 MLLTSYLPPPLLRHRLKTHTTVIHQLDKALAKLGIGQLTAQEVKSACYLRGLNSTHIGED
. : .. ::: .: . :. :. .:: :. :...:...:: ::. : . :.
CCDS69 LELQTFGTNNLLRFQLLMKLKSIKADDEIIAKEGVTALSVSELQAACRARGMRSLGLTEE
310 320 330 340 350 360
330 340 350 360
pF1KE3 RCRTWLGEWLQISCSLKE-AELSLLLHNVVLLSTNYLGTRR
. : : :: .. ::: . ::::
CCDS69 QLRQQLTEWQDL--HLKENVPPSLLLLSRTFYLIDVKPKPIEIPLSGEAPKTDILVELPT
370 380 390 400 410
>>CCDS56534.1 LETM2 gene_id:137994|Hs108|chr8 (444 aa)
initn: 236 init1: 139 opt: 273 Z-score: 341.0 bits: 72.0 E(32554): 1.1e-12
Smith-Waterman score: 273; 24.0% identity (54.9% similar) in 337 aa overlap (20-345:15-337)
10 20 30 40 50
pF1KE3 MALSRVCWARSAVWGSAVTPGHFV----TRRLQLGRSGLAWGAPRSSKLHLSPKADVKNL
::. : :: .: ... : .: .: . ..
CCDS56 MKNYESKKYSDPSQPGNTVLHPGTRLIQKLHTSTCWLQEVPGKPQLEQATKHPQV
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 MSYVVTKTKAINGKYHRFLGRHFPRFYVLYTI--FMKGLQMLWADAKKARRIKTNMWKHN
: .:: ... : :.. : .. . ...:. .:: ::: : :. .:.
CCDS56 TSPQATKETGMEIKE----GKQSYRQKIMDELKYYYNGFYLLWIDAKVAARM---VWRL-
60 70 80 90 100
120 130 140 150 160 170
pF1KE3 IKFHQLPYREMEHLRQFRQDVTKCLFLGIISIPPFANYLVFLLMYLFPRQLLIRHFWTP-
.. . : :: ..: . : . . . .. : :: ..:. ... ::: ..: : .
CCDS56 LHGQVLTRRERRRLLRTCVDFFRLVPFMVFLIVPFMEFLLPVFLKLFP-EMLPSTFESES
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE3 ---KQQTDFLDIYHAFRKQSHPEIISYLEKVIPLISDAGLRWRLTDLCTKIQRGTHPAIH
..: . . . : . . . .. ..::. .:.. ..: : .:. .
CCDS56 KKEEKQKKKMAVKLELAKFLQETMTEMARRNRAKMGDAST--QLSSYVKQVQTGHKPSTK
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE3 DILALRECFSNHPLGMNQLQALHVKALSRAMLLTSYLPPPLLRHRLKTHTTVIHQLDKAL
.:. . . : .. :....:. .. :: . . : .. ::: .: . :. :. .
CCDS56 EIVRFSKLFEDQ-LALEHLDRPQLVALCKLLELQTFGTNNLLRFQLLMKLKSIKADDEII
230 240 250 260 270 280
300 310 320 330 340
pF1KE3 AKLGIGQLTAQEVKSACYLRGLNSTHIGEDRCRTWLGEWLQISCSLKE-AELSLLLHNVV
:: :. :...:...:: ::. : . :.. : : :: .. ::: . ::::
CCDS56 AKEGVTALSVSELQAACRARGMRSLGLTEEQLRQQLTEWQDL--HLKENVPPSLLLLSRT
290 300 310 320 330 340
350 360
pF1KE3 LLSTNYLGTRR
CCDS56 FYLIDVKPKPIEIPLSGEAPKTDILVELPTFTESKENMVDLAPQLKGTKDEDFIQPPPVT
350 360 370 380 390 400
>>CCDS3355.1 LETM1 gene_id:3954|Hs108|chr4 (739 aa)
initn: 193 init1: 148 opt: 263 Z-score: 325.0 bits: 69.7 E(32554): 8.7e-12
Smith-Waterman score: 263; 25.0% identity (58.0% similar) in 264 aa overlap (89-345:164-416)
60 70 80 90 100 110
pF1KE3 YVVTKTKAINGKYHRFLGRHFPRFYVLYTIFMKGLQMLWADAKKARRIKTNMWKHNIKFH
...:...:: :.: : :. .:. .. :
CCDS33 LEEGGPVYSPPAEVVVKKSLGQRVLDELKHYYHGFRLLWIDTKIAARM---LWR-ILNGH
140 150 160 170 180
120 130 140 150 160 170
pF1KE3 QLPYREMEHLRQFRQDVTKCLFLGIISIPPFANYLVFLLMYLFPRQLLIRHFWTPKQQTD
.: :: ... .. :. . . . .. . :: ..:. . . ::: ..: : : . . .
CCDS33 SLTRRERRQFLRICADLFRLVPFLVFVVVPFMEFLLPVAVKLFP-NMLPSTFETQSLKEE
190 200 210 220 230 240
180 190 200 210 220 230
pF1KE3 FLDIYHAFRKQSHPEIISYLEKVIP---LISDAGLRWRLTDLCTKIQR----GTHPAIHD
: . .: . :. ..:. .: : . :. :. . .:. : .:. ..
CCDS33 RLK--KELRVKL--ELAKFLQDTIEEMALKNKAAKGSATKDFSVFFQKIRETGERPSNEE
250 260 270 280 290 300
240 250 260 270 280 290
pF1KE3 ILALRECFSNHPLGMNQLQALHVKALSRAMLLTSYLPPPLLRHRLKTHTTVIHQLDKALA
:. . . : .. : ...: .. :: . . : : .:: .: . :. :: .:
CCDS33 IMRFSKLFEDE-LTLDNLTRPQLVALCKLLELQSIGTNNFLRFQLTMRLRSIKADDKLIA
310 320 330 340 350 360
300 310 320 330 340 350
pF1KE3 KLGIGQLTAQEVKSACYLRGLNSTHIGEDRCRTWLGEWLQISCSLKEAELSLLLHNVVLL
. :. .:...:...:: ::. . . ::: : : .::.. .: :::.
CCDS33 EEGVDSLNVKELQAACRARGMRALGVTEDRLRGQLKQWLDLHLH-QEIPTSLLILSRAMY
370 380 390 400 410 420
360
pF1KE3 STNYLGTRR
CCDS33 LPDTLSPADQLKSTLQTLPEIVAKEAQVKVAEVEGEQVDNKAKLEATLQEEAAIQQEHRE
430 440 450 460 470 480
360 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 14:50:07 2016 done: Sun Nov 6 14:50:08 2016
Total Scan time: 2.680 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]