Result of FASTA (omim) for
pFN21AE3126
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3126, 318 aa
1>>>pF1KE3126 318 - 318 aa - 318 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.6833+/-0.000311; mu= 8.1548+/- 0.019
mean_var=200.1365+/-40.644, 0's: 0 Z-trim(123.5): 134 B-trim: 757 in 1/58
Lambda= 0.090659
statistics sampled from 43159 (43294) to 43159 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.804), E-opt: 0.2 (0.508), width: 16
Scan time: 9.440
The best scores are: opt bits E(85289)
NP_036320 (OMIM: 274600,600791,601093) forkhead bo ( 378) 896 128.8 1.7e-29
NP_001129121 (OMIM: 612351) forkhead box protein I ( 420) 781 113.9 6.1e-25
NP_658982 (OMIM: 274600,600791,601093) forkhead bo ( 283) 648 96.3 8e-20
NP_004463 (OMIM: 601091) forkhead box protein D1 [ ( 465) 568 86.0 1.6e-16
NP_036318 (OMIM: 107250,601094,610256) forkhead bo ( 319) 551 83.6 5.7e-16
NP_001444 (OMIM: 601090,601631,602482) forkhead bo ( 553) 550 83.8 9.2e-16
NP_710141 (OMIM: 600288) hepatocyte nuclear factor ( 457) 548 83.4 9.6e-16
NP_068556 (OMIM: 600288) hepatocyte nuclear factor ( 463) 548 83.4 9.7e-16
NP_036315 (OMIM: 607836,611539) forkhead box prote ( 478) 531 81.2 4.6e-15
NP_005242 (OMIM: 153400,602402) forkhead box prote ( 501) 529 81.0 5.7e-15
NP_004109 (OMIM: 602939) forkhead box protein S1 [ ( 330) 524 80.1 6.8e-15
NP_001443 (OMIM: 603250) forkhead box protein F2 [ ( 444) 516 79.2 1.7e-14
NP_004464 (OMIM: 241850,602617,616534) forkhead bo ( 373) 514 78.9 1.8e-14
NP_005241 (OMIM: 603252) forkhead box protein L1 [ ( 345) 508 78.1 3e-14
NP_004488 (OMIM: 602295) hepatocyte nuclear factor ( 350) 504 77.5 4.3e-14
NP_004465 (OMIM: 602211) forkhead box protein D2 [ ( 495) 502 77.4 6.6e-14
NP_150285 (OMIM: 612788) forkhead box protein Q1 [ ( 403) 488 75.5 2e-13
NP_005240 (OMIM: 164874,613454) forkhead box prote ( 489) 481 74.7 4.4e-13
NP_001442 (OMIM: 265380,601089) forkhead box prote ( 379) 477 74.0 5.3e-13
XP_016876735 (OMIM: 602294) PREDICTED: hepatocyte ( 439) 476 74.0 6.4e-13
NP_004487 (OMIM: 602294) hepatocyte nuclear factor ( 472) 476 74.0 6.7e-13
NP_075555 (OMIM: 110100,605597,608996) forkhead bo ( 376) 468 72.9 1.2e-12
NP_954714 (OMIM: 611085) forkhead box protein D4-l ( 416) 455 71.2 4.1e-12
NP_954586 (OMIM: 611086) forkhead box protein D4-l ( 417) 455 71.2 4.1e-12
NP_036316 (OMIM: 611084) forkhead box protein D4-l ( 408) 446 70.0 9.2e-12
NP_997188 (OMIM: 601092) forkhead box protein D4 [ ( 439) 438 69.0 2e-11
XP_006710521 (OMIM: 616035) PREDICTED: forkhead bo ( 607) 403 64.6 6e-10
XP_011539328 (OMIM: 616035) PREDICTED: forkhead bo ( 622) 403 64.6 6.1e-10
NP_055762 (OMIM: 616035) forkhead box protein J3 i ( 622) 403 64.6 6.1e-10
NP_001185779 (OMIM: 616035) forkhead box protein J ( 622) 403 64.6 6.1e-10
NP_001185780 (OMIM: 616035) forkhead box protein J ( 622) 403 64.6 6.1e-10
XP_005270689 (OMIM: 616035) PREDICTED: forkhead bo ( 630) 403 64.6 6.2e-10
XP_016856182 (OMIM: 616035) PREDICTED: forkhead bo ( 573) 399 64.0 8.3e-10
NP_001185781 (OMIM: 616035) forkhead box protein J ( 588) 399 64.0 8.4e-10
XP_006710522 (OMIM: 616035) PREDICTED: forkhead bo ( 596) 399 64.0 8.5e-10
NP_001445 (OMIM: 602291) forkhead box protein J1 [ ( 421) 380 61.4 3.7e-09
NP_004505 (OMIM: 147685) forkhead box protein K2 [ ( 660) 380 61.6 5.1e-09
XP_011513493 (OMIM: 616302) PREDICTED: forkhead bo ( 570) 372 60.5 9.5e-09
NP_001032242 (OMIM: 616302) forkhead box protein K ( 733) 372 60.6 1.1e-08
NP_003914 (OMIM: 603621) forkhead box protein H1 [ ( 365) 355 58.1 3.3e-08
XP_005258103 (OMIM: 600838,601705) PREDICTED: fork ( 648) 346 57.1 1.1e-07
NP_003584 (OMIM: 600838,601705) forkhead box prote ( 648) 346 57.1 1.1e-07
XP_011523664 (OMIM: 600838,601705) PREDICTED: fork ( 648) 345 57.0 1.2e-07
XP_016880717 (OMIM: 600838,601705) PREDICTED: fork ( 648) 345 57.0 1.2e-07
XP_011523661 (OMIM: 600838,601705) PREDICTED: fork ( 649) 345 57.0 1.2e-07
XP_011523660 (OMIM: 600838,601705) PREDICTED: fork ( 649) 345 57.0 1.2e-07
XP_011523669 (OMIM: 600838,601705) PREDICTED: fork ( 462) 342 56.5 1.3e-07
XP_011523671 (OMIM: 600838,601705) PREDICTED: fork ( 436) 339 56.1 1.6e-07
XP_011523670 (OMIM: 600838,601705) PREDICTED: fork ( 436) 339 56.1 1.6e-07
XP_011523672 (OMIM: 600838,601705) PREDICTED: fork ( 436) 339 56.1 1.6e-07
>>NP_036320 (OMIM: 274600,600791,601093) forkhead box pr (378 aa)
initn: 867 init1: 799 opt: 896 Z-score: 650.6 bits: 128.8 E(85289): 1.7e-29
Smith-Waterman score: 915; 54.3% identity (75.6% similar) in 254 aa overlap (17-258:39-291)
10 20 30 40
pF1KE3 MATYCDDLGPSSAPPGQAQATAHPPGYEPGDLGAVGGGPLLWVNAP
:. . . :..: : .. .: :: :.:
NP_036 PSPPRCSPQFPSIGQEPPEMNLYYENFFHPQGVPSPQRPSFEGGGEYGATPNPYLWFNGP
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 ALSPKSYASGPGPAPPYAAPSYGAPGPLLGAPGGLAGADLAWLSLSGQQELLRLVRPPYS
...: : ::. : :. .::. ::: . .::.:.::.:: . .:.::..:::::::
NP_036 TMTPPPYLPGPN-ASPFLPQAYGVQRPLLPSVSGLGGSDLGWLPIPSQEELMKLVRPPYS
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 YSALIAMAIQSAPLRKLTLSQIYQYVAGNFPFYKRSKAGWQNSIRHNLSLNDCFKKVPRD
:::::::::..:: ..::::::::::: :::::..:::::::::::::::::::::::::
NP_036 YSALIAMAIHGAPDKRLTLSQIYQYVADNFPFYNKSKAGWQNSIRHNLSLNDCFKKVPRD
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE3 EDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRRAEASAAVRSGARSVGGAEAPALEPPSAA
:::::::::::::::::::::::::::::::....:... : : . :. : ..
NP_036 EDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRKSDVSSSTASLALEKTESSLPVDSPKTTE
190 200 210 220 230 240
230 240 250 260 270
pF1KE3 CLDLQASPSP----SAPE--------AATCFSGFASAMSALAGGLGTFPGGLAGDFSFGR
:. . :: :.:: .: :...: :.:.: ..:
NP_036 PQDILDGASPGGTTSSPEKRPSPPPSGAPCLNSFLSSMTAYVSGGSPTSHPLVTPGLSPE
250 260 270 280 290 300
280 290 300 310
pF1KE3 RPPTVATHAPQTLNPSPGFAPGHQTAAAGFRLSHLLYSREGTEV
NP_036 PSDKTGQNSLTFNSFSPLTNLSNHSGGGDWANPMPTNMLSYGGSVLSQFSPHFYNSVNTS
310 320 330 340 350 360
>>NP_001129121 (OMIM: 612351) forkhead box protein I3 [H (420 aa)
initn: 825 init1: 726 opt: 781 Z-score: 568.8 bits: 113.9 E(85289): 6.1e-25
Smith-Waterman score: 813; 52.4% identity (68.5% similar) in 292 aa overlap (8-267:39-320)
10 20 30
pF1KE3 MATYCDDLGPSSAPPGQAQATAHPPGYEPGDLGAVGG
:. .:::. :.:.: . : .:::
NP_001 FGVYSQPGLPPPAATAAAPGAPPAARAPYGLADYAAPPA---AAANPYLWLNGP--GVGG
10 20 30 40 50 60
40 50 60 70 80
pF1KE3 GPLLWVNA--------PALSPKSYASGPGPAPPYAAPSYGA-------PGPLLGA-PGGL
: . : : : . :.:: :: :: ..: :.: : :..
NP_001 PPSAAAAAAAAYLGAPPPPPPPGAAAGPFLQPPPAAGTFGCSQRPFAQPAPAAPASPAAP
70 80 90 100 110 120
90 100 110 120 130 140
pF1KE3 AG-ADLAWLSLSGQQELLRLVRPPYSYSALIAMAIQSAPLRKLTLSQIYQYVAGNFPFYK
:: ..:.:::......:...::::::::::::::::::: ::::::.:::.:: .::::.
NP_001 AGPGELGWLSMASREDLMKMVRPPYSYSALIAMAIQSAPERKLTLSHIYQFVADSFPFYQ
130 140 150 160 170 180
150 160 170 180 190 200
pF1KE3 RSKAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
NP_001 RSKAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRRSE
190 200 210 220 230 240
210 220 230 240
pF1KE3 AS-----AA--------VRSGARS-VGGAEAPALEPPSAACLDLQASPSPSAPEAA-TCF
:: :: . :: : ::: : : ::. :. : :: ::.. .
NP_001 ASNGSTVAAGTSKSEEGLSSGLGSGVGG--KPEEESPSTL---LRPSHSPEPPEGTKSTA
250 260 270 280 290
250 260 270 280 290 300
pF1KE3 SGFASAMSALAGGLGTFPGGLAGDFSFGRRPPTVATHAPQTLNPSPGFAPGHQTAAAGFR
:. .. : . . :.:: ..:.
NP_001 SSPGGPMLTSTPCLNTFFSSLSSLSVSSSVSTQRALPGSRHLGIQGAQLPSSGVFSPTSI
300 310 320 330 340 350
>>NP_658982 (OMIM: 274600,600791,601093) forkhead box pr (283 aa)
initn: 630 init1: 562 opt: 648 Z-score: 476.9 bits: 96.3 E(85289): 8e-20
Smith-Waterman score: 648; 60.4% identity (81.2% similar) in 154 aa overlap (17-170:39-191)
10 20 30 40
pF1KE3 MATYCDDLGPSSAPPGQAQATAHPPGYEPGDLGAVGGGPLLWVNAP
:. . . :..: : .. .: :: :.:
NP_658 PSPPRCSPQFPSIGQEPPEMNLYYENFFHPQGVPSPQRPSFEGGGEYGATPNPYLWFNGP
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 ALSPKSYASGPGPAPPYAAPSYGAPGPLLGAPGGLAGADLAWLSLSGQQELLRLVRPPYS
...: : ::. : :. .::. ::: . .::.:.::.:: . .:.::..:::::::
NP_658 TMTPPPYLPGPN-ASPFLPQAYGVQRPLLPSVSGLGGSDLGWLPIPSQEELMKLVRPPYS
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 YSALIAMAIQSAPLRKLTLSQIYQYVAGNFPFYKRSKAGWQNSIRHNLSLNDCFKKVPRD
:::::::::..:: ..::::::::::: :::::..:::::::::::::::::::::::::
NP_658 YSALIAMAIHGAPDKRLTLSQIYQYVADNFPFYNKSKAGWQNSIRHNLSLNDCFKKVPRD
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE3 EDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRRAEASAAVRSGARSVGGAEAPALEPPSAA
::::
NP_658 EDDPAYVSGGSPTSHPLVTPGLSPEPSDKTGQNSLTFNSFSPLTNLSNHSGGGDWANPMP
190 200 210 220 230 240
>>NP_004463 (OMIM: 601091) forkhead box protein D1 [Homo (465 aa)
initn: 542 init1: 505 opt: 568 Z-score: 417.7 bits: 86.0 E(85289): 1.6e-16
Smith-Waterman score: 578; 40.9% identity (60.2% similar) in 279 aa overlap (55-301:83-356)
30 40 50 60 70 80
pF1KE3 PGYEPGDLGAVGGGPLLWVNAPALSPKSYASGPGPAPPYAAPSYGAPGPLLGAPGGLAGA
.: .:::: ::. :: . :. :: .::
NP_004 RRRRRSYAGEDELEDLEEEEDDDDILLAPPAGGSPAPPGPAPAAGAGA---GGGGGGGGA
60 70 80 90 100
90 100 110 120 130 140
pF1KE3 DLAWLSLSGQQELLRLVRPPYSYSALIAMAIQSAPLRKLTLSQIYQYVAGNFPFYKRSKA
. . :: .. ::.::::: :::.::: ..: ..::::.: ....: ::.:...
NP_004 GGGGSAGSGAKN--PLVKPPYSYIALITMAILQSPKKRLTLSEICEFISGRFPYYREKFP
110 120 130 140 150 160
150 160 170 180 190
pF1KE3 GWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKR-------
.::::::::::::::: :.::. .:::::::::::. :::::.: :.:::
NP_004 AWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPESADMFDNGSFLRRRKRFKRQPLL
170 180 190 200 210 220
200 210 220 230
pF1KE3 ---RAEASAAVRSGARSVGGAEAPA----LEPPSA------------AC-LDLQASP--S
: : . . :: ..::: :: : ::. .: :: :
NP_004 PPNAAAAESLLLRGAGAAGGAGDPAAAAALFPPAPPPPPHAYGYGPYGCGYGLQLPPYAP
230 240 250 260 270 280
240 250 260 270 280 290
pF1KE3 PSAPEAATCFSGFASAMSALAGGLGTFPGGLAGDFS---FGRRPPTVATHAPQTLNPSPG
::: ::. .. :.:. . : : :.... :: :: ... : : : .
NP_004 PSALFAAAAAAAAAAAFHPHSPPPPPPPHGAAAELARTAFGYRPHPLGAALPGPLPASAA
290 300 310 320 330 340
300 310
pF1KE3 FAPGHQTAAAGFRLSHLLYSREGTEV
: : ..:
NP_004 KAGGPGASALARSPFSIESIIGGSLGPAAAAAAAAQAAAAAQASPSPSPVAAPPAPGSSG
350 360 370 380 390 400
>>NP_036318 (OMIM: 107250,601094,610256) forkhead box pr (319 aa)
initn: 509 init1: 449 opt: 551 Z-score: 407.7 bits: 83.6 E(85289): 5.7e-16
Smith-Waterman score: 559; 42.4% identity (57.6% similar) in 269 aa overlap (34-291:12-266)
10 20 30 40 50 60
pF1KE3 YCDDLGPSSAPPGQAQATAHPPGYEPGDLGAVGGGPLLWVNAPALSPKSYASG--PGPAP
: .: : : . ::. : : .: :: :
NP_036 MAGRSDMDPPAAFSGFPALPAVAPSGPPPSPLAGAEPGREP
10 20 30 40
70 80 90 100 110
pF1KE3 PYAAPSYG--APGPLLGAPGGLAGADLAWLSLSGQQELLRLVRPPYSYSALIAMAIQSAP
:: . : :: : ::: : ... :. .::::: ::::::. ::
NP_036 EEAAAGRGEAAPTP---APG--PGRR--------RRRPLQRGKPPYSYIALIAMALAHAP
50 60 70 80
120 130 140 150 160 170
pF1KE3 LRKLTLSQIYQYVAGNFPFYKRSKAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLD
:.:::. ::.... : ::. : :::::::::.::::: ::::. .::::::::::
NP_036 GRRLTLAAIYRFITERFAFYRDSPRKWQNSIRHNLTLNDCFVKVPREPGNPGKGNYWTLD
90 100 110 120 130 140
180 190 200 210 220 230
pF1KE3 PNCEKMFDNGNFRRKRKR--RAE--ASAAVRSGARSVGGAEAPALEPPSAACL--DLQAS
: :::::.: :.::: ::: : ::. : . :: :. : : .:.
NP_036 PAAADMFDNGSFLRRRKRFKRAELPAHAAAAPGP-PLPFPYAPYAPAPGPALLVPPPSAG
150 160 170 180 190 200
240 250 260 270 280 290
pF1KE3 PSPSAPEAATCFSGFASAMSALAG-GLGTFPGGLAGDFSFGRRPPTVATHAPQTLNPSPG
:.:: : ..... . ::: : : : : . . :: .:. .: . :
NP_036 PGPSPPARLFSVDSLVNLQPELAGLGAPEPPCCAAPDAAAAAFPPCAAAASPPLYSQVPD
210 220 230 240 250 260
300 310
pF1KE3 FAPGHQTAAAGFRLSHLLYSREGTEV
NP_036 RLVLPATRPGPGPLPAEPLLALAGPAAALGPLSPGEAYLRQPGFASGLERYL
270 280 290 300 310
>>NP_001444 (OMIM: 601090,601631,602482) forkhead box pr (553 aa)
initn: 537 init1: 473 opt: 550 Z-score: 404.0 bits: 83.8 E(85289): 9.2e-16
Smith-Waterman score: 593; 36.0% identity (59.0% similar) in 322 aa overlap (29-316:10-320)
10 20 30 40 50
pF1KE3 MATYCDDLGPSSAPPGQAQATAHPPGYEPGDLGAV---GGGPLLWVNAPALSPKSYASGP
:..::.: :: . : : . .:.. :
NP_001 MQARYSVSSPNSLGVVPYLGGEQSYYRAAAAAAGGGYTAMP
10 20 30 40
60 70 80 90 100 110
pF1KE3 GPAPPYAAPSYGAPGPLLGAPGGLAGADLAWLSLSGQQELLRLVRPPYSYSALIAMAIQS
.: :. :... :::.: :. . : . .:.::::: :::.::::.
NP_001 APMSVYSHPAHAEQ-----YPGGMAR---AYGPYTPQPQPKDMVKPPYSYIALITMAIQN
50 60 70 80 90
120 130 140 150 160 170
pF1KE3 APLRKLTLSQIYQYVAGNFPFYKRSKAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWT
:: .:.::. :::.. ::::. .: :::::::::::::.:: :::::. ::::.:::
NP_001 APDKKITLNGIYQFIMDRFPFYRDNKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWT
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE3 LDPNCEKMFDNGNFRRKRKRRAEASAAVRSGARS----VGGAEAPALEPPSAACLDLQAS
:::. .::.::.: : :.:: . . ::.. .. . :. .:: : . ...
NP_001 LDPDSYNMFENGSFLR-RRRRFKKKDAVKDKEEKDRLHLKEPPPPGRQPPPAPPEQADGN
160 170 180 190 200 210
240 250 260 270
pF1KE3 -PSPSAP---------EAATCFSGFASAMSALAGGLGTF--------PGGLAGDFSFGRR
:.:. : : .:: : : : : :. : . ....: :
NP_001 APGPQPPPVRIQDIKTENGTCPSPPQPLSPAAALGSGSAAAVPKIESPDSSSSSLSSGSS
220 230 240 250 260 270
280 290 300 310
pF1KE3 PP-TVATHAPQTLN--------PSPGFAPGHQTAAAGFRLSHLLYSREGTEV
:: .. . : .:. :.:. : :.. :: ..... : .:.
NP_001 PPGSLPSARPLSLDGADSAPPPPAPSAPPPHHSQ--GFSVDNIMTSLRGSPQSAAAELSS
280 290 300 310 320 330
NP_001 GLLASAAASSRAGIAPPLALGAYSPGQSSLYSSPCSQTSSAGSSGGGGGGAGAAGGAGGA
340 350 360 370 380 390
>>NP_710141 (OMIM: 600288) hepatocyte nuclear factor 3-b (457 aa)
initn: 457 init1: 435 opt: 548 Z-score: 403.6 bits: 83.4 E(85289): 9.6e-16
Smith-Waterman score: 553; 37.0% identity (59.3% similar) in 322 aa overlap (1-308:65-374)
10 20
pF1KE3 MATYCD-DLGPSSA--PPGQAQATAHPPGY
:..: ..:: : :: : : : :
NP_710 LGMNGMNTYMSMSAAAMGSGSGNMSAGSMNMSSYVGAGMSPSLAGMSPG-AGAMAGMGG-
40 50 60 70 80 90
30 40 50 60 70 80
pF1KE3 EPGDLGAVGGGPLLWVNAPALSP-KSYASGP-GPAPPYAAPSYGAPGPLLGAPGGLAGAD
: :..: :: : .:.::: . :.: : ::: .... .:. : : . :
NP_710 SAGAAGVAGMGPHL---SPSLSPLGGQAAGAMGGLAPYA--NMNSMSPMYGQAGLSRARD
100 110 120 130 140
90 100 110 120 130 140
pF1KE3 LAWLSLSGQQELLRLVRPPYSYSALIAMAIQSAPLRKLTLSQIYQYVAGNFPFYKRSKAG
: . ..::::: .::.::::..: . ::::.:::.. ::::....
NP_710 PKTYRRSYTH-----AKPPYSYISLITMAIQQSPNKMLTLSEIYQWIMDLFPFYRQNQQR
150 160 170 180 190 200
150 160 170 180 190 200
pF1KE3 WQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKR-RAEASAA
:::::::.::.:::: ::::. : ::::..::: :. .::.:: . :..:: . : . :
NP_710 WQNSIRHSLSFNDCFLKVPRSPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKCEKQLA
210 220 230 240 250 260
210 220 230 240 250 260
pF1KE3 VRSGARSVG-GAEAPALEPPSAACLDLQASPSPSAPEAATCFSGFASAMSALA-GGLGTF
.. .: ..: : .: : : : : :.:. .: .. . :: . :::: .
NP_710 LKEAAGAAGSGKKAAAGAQASQAQLGEAAGPASETPAGTESPHSSASPCQEHKRGGLGEL
270 280 290 300 310 320
270 280 290 300 310
pF1KE3 PGGLAGDFSFGRRPPTVATH---APQTLNPS--PGFAP-GHQTAAAGFRLSHLLYSREGT
: :. .: . :. . . : . :.: ::. : .: . ..:
NP_710 KGTPAAALSPPEPAPSPGQQQQAAAHLLGPPHHPGLPPEAHLKPEHHYAFNHPFSINNLM
330 340 350 360 370 380
pF1KE3 EV
NP_710 SSEQQHHHSHHHHQPHKMDLKAYEQVMHYPGYGSPMPGSLAMGPVTNKTGLDASPLAADT
390 400 410 420 430 440
>>NP_068556 (OMIM: 600288) hepatocyte nuclear factor 3-b (463 aa)
initn: 457 init1: 435 opt: 548 Z-score: 403.6 bits: 83.4 E(85289): 9.7e-16
Smith-Waterman score: 553; 37.0% identity (59.3% similar) in 322 aa overlap (1-308:71-380)
10 20
pF1KE3 MATYCD-DLGPSSA--PPGQAQATAHPPGY
:..: ..:: : :: : : : :
NP_068 LGMNGMNTYMSMSAAAMGSGSGNMSAGSMNMSSYVGAGMSPSLAGMSPG-AGAMAGMGG-
50 60 70 80 90
30 40 50 60 70 80
pF1KE3 EPGDLGAVGGGPLLWVNAPALSP-KSYASGP-GPAPPYAAPSYGAPGPLLGAPGGLAGAD
: :..: :: : .:.::: . :.: : ::: .... .:. : : . :
NP_068 SAGAAGVAGMGPHL---SPSLSPLGGQAAGAMGGLAPYA--NMNSMSPMYGQAGLSRARD
100 110 120 130 140 150
90 100 110 120 130 140
pF1KE3 LAWLSLSGQQELLRLVRPPYSYSALIAMAIQSAPLRKLTLSQIYQYVAGNFPFYKRSKAG
: . ..::::: .::.::::..: . ::::.:::.. ::::....
NP_068 PKTYRRSYTH-----AKPPYSYISLITMAIQQSPNKMLTLSEIYQWIMDLFPFYRQNQQR
160 170 180 190 200
150 160 170 180 190 200
pF1KE3 WQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKR-RAEASAA
:::::::.::.:::: ::::. : ::::..::: :. .::.:: . :..:: . : . :
NP_068 WQNSIRHSLSFNDCFLKVPRSPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKCEKQLA
210 220 230 240 250 260
210 220 230 240 250 260
pF1KE3 VRSGARSVG-GAEAPALEPPSAACLDLQASPSPSAPEAATCFSGFASAMSALA-GGLGTF
.. .: ..: : .: : : : : :.:. .: .. . :: . :::: .
NP_068 LKEAAGAAGSGKKAAAGAQASQAQLGEAAGPASETPAGTESPHSSASPCQEHKRGGLGEL
270 280 290 300 310 320
270 280 290 300 310
pF1KE3 PGGLAGDFSFGRRPPTVATH---APQTLNPS--PGFAP-GHQTAAAGFRLSHLLYSREGT
: :. .: . :. . . : . :.: ::. : .: . ..:
NP_068 KGTPAAALSPPEPAPSPGQQQQAAAHLLGPPHHPGLPPEAHLKPEHHYAFNHPFSINNLM
330 340 350 360 370 380
pF1KE3 EV
NP_068 SSEQQHHHSHHHHQPHKMDLKAYEQVMHYPGYGSPMPGSLAMGPVTNKTGLDASPLAADT
390 400 410 420 430 440
>>NP_036315 (OMIM: 607836,611539) forkhead box protein D (478 aa)
initn: 505 init1: 465 opt: 531 Z-score: 391.4 bits: 81.2 E(85289): 4.6e-15
Smith-Waterman score: 555; 37.6% identity (59.5% similar) in 311 aa overlap (6-306:59-337)
10 20 30
pF1KE3 MATYCDDLGPSSAPPGQAQATAHPPGYEPGDLGAV
:.. :.. :: : . : : . ...
NP_036 GEGDDGLEEKDSDAGCDSPAGPPELRLDEADEVPPAAPHHGQPQPPHQQPLTLPKEAAGA
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE3 GGGPLLWVNAPALSPKSYASGPGPAPPYAAPSYGAPGPLLGAPGGLAGADLAWLSLSGQQ
:.:: :.:: .. . : . .. : :.:: :. :::: . .
NP_036 GAGPGGDVGAP----EADGCKGGVGGEEGGASGGGPGAGSGSAGGLAPS----------K
90 100 110 120 130
100 110 120 130 140 150
pF1KE3 ELLRLVRPPYSYSALIAMAIQSAPLRKLTLSQIYQYVAGNFPFYKRSKAGWQNSIRHNLS
::.::::: :::.::: ..: .::::: : ..... ::.:... .::::::::::
NP_036 PKNSLVKPPYSYIALITMAILQSPQKKLTLSGICEFISNRFPYYREKFPAWQNSIRHNLS
140 150 160 170 180 190
160 170 180 190 200
pF1KE3 LNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKR---------RAEASAAVR
::::: :.::. .:::::::::::. : :::::.: :.::: : ... ..
NP_036 LNDCFVKIPREPGNPGKGNYWTLDPQSEDMFDNGSFLRRRKRFKRHQQEHLREQTALMMQ
200 210 220 230 240 250
210 220 230 240 250 260
pF1KE3 S-GARSVGGAEAPALEPPSAACLDLQASPSPSAPEAATCFSGFASAMSALAGGLGTFPGG
: :: :...: . : : . :. :.: :: .: :.: .: :.. .: .
NP_036 SFGAYSLAAAAGAA--GPYGRPYGLH----PAA--AAGAYSHPAAAAAAAAAAALQYPYA
260 270 280 290 300
270 280 290 300 310
pF1KE3 LAGDFSFGRRPPTVATHAPQTLNPSPGFAPGHQTAAAGFRLSHLLYSREGTEV
: :: :: : .. :. :...:: : .:
NP_036 L---------PP-VAPVLPPAVPLLPSGELGRKAAAFGSQLGPGLQLQLNSLGAAAAAAG
310 320 330 340 350
NP_036 TAGAAGTTASLIKSEPSARPSFSIENIIGGGPAAPGGSAVGAGVAGGTGGSGGGSTAQSF
360 370 380 390 400 410
>>NP_005242 (OMIM: 153400,602402) forkhead box protein C (501 aa)
initn: 530 init1: 488 opt: 529 Z-score: 389.7 bits: 81.0 E(85289): 5.7e-15
Smith-Waterman score: 530; 38.6% identity (58.1% similar) in 277 aa overlap (46-313:17-279)
20 30 40 50 60 70
pF1KE3 GQAQATAHPPGYEPGDLGAVGGGPLLWVNAPALSPKSYASGPGPAPPYAAPSYGAPGPLL
: :: ..: . : .:.: :
NP_005 MQARYSVSDPNALGVVPYLSEQNYYRAAGSYGGMASPM----GVYS
10 20 30 40
80 90 100 110 120 130
pF1KE3 GAPGGL-AGADLAWLSLSGQQELL--RLVRPPYSYSALIAMAIQSAPLRKLTLSQIYQYV
: : :: .. .: ::.::::: :::.::::.:: .:.::. :::..
NP_005 GHPEQYSAGMGRSYAPYHHHQPAAPKDLVKPPYSYIALITMAIQNAPEKKITLNGIYQFI
50 60 70 80 90 100
140 150 160 170 180 190
pF1KE3 AGNFPFYKRSKAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFR
::::...: :::::::::::::.:: :::::. ::::.::::::. .::.::.:
NP_005 MDRFPFYRENKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFL
110 120 130 140 150 160
200 210 220 230 240 250
pF1KE3 RKRKRRAEASAAVRSGARSVGGAEAPALEPPSAACLDLQASPS-PSAPEAATCFSGFASA
:.:.: . ... .. : : ::: :: :.: .::. : . :
NP_005 RRRRRFKKKDVSKEKEER------AHLKEPPPAASKGAPATPHLADAPKEAEKKVVIKSE
170 180 190 200 210
260 270 280 290 300
pF1KE3 MSALAGGLGTFPGGLAGDFSFGRRPPTVATHAPQTLNPSP-GFAPGHQTAAA----GFRL
.. : . : :. . .. : ..:. : :: : : :..:: :: .
NP_005 AASPALPVITKVETLSPESALQGSPRSAAS----TPAGSPDGSLPEHHAAAPNGLPGFSV
220 230 240 250 260 270
310
pF1KE3 SHLLYSREGTEV
... :
NP_005 ENIMTLRTSPPGGELSPGAGRAGLVVPPLALPYAAAPPAAYGQPCAQGLEAGAAGGYQCS
280 290 300 310 320 330
318 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 04:31:17 2016 done: Tue Nov 8 04:31:19 2016
Total Scan time: 9.440 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]