Result of FASTA (omim) for
pFN21AE3124
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3124, 313 aa
1>>>pF1KE3124 313 - 313 aa - 313 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1410+/-0.000386; mu= 16.5492+/- 0.024
mean_var=61.9964+/-12.801, 0's: 0 Z-trim(113.0): 55 B-trim: 1594 in 2/49
Lambda= 0.162889
statistics sampled from 22147 (22206) to 22147 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.647), E-opt: 0.2 (0.26), width: 16
Scan time: 7.480
The best scores are: opt bits E(85289)
NP_114160 (OMIM: 613421) BTB/POZ domain-containing ( 313) 2047 489.6 3.5e-138
NP_001304324 (OMIM: 613421) BTB/POZ domain-contain ( 314) 2035 486.7 2.5e-137
NP_066960 (OMIM: 191161) BTB/POZ domain-containing ( 316) 1452 349.7 4.4e-96
NP_849194 (OMIM: 608947) BTB/POZ domain-containing ( 329) 1418 341.8 1.2e-93
XP_016880482 (OMIM: 191161) PREDICTED: BTB/POZ dom ( 391) 1234 298.6 1.4e-80
NP_001304328 (OMIM: 613421) BTB/POZ domain-contain ( 290) 1120 271.7 1.3e-72
XP_011544086 (OMIM: 608947) PREDICTED: BTB/POZ dom ( 202) 883 215.9 5.4e-56
XP_011544085 (OMIM: 608947) PREDICTED: BTB/POZ dom ( 347) 883 216.1 8.5e-56
XP_016878593 (OMIM: 608947) PREDICTED: BTB/POZ dom ( 178) 833 204.1 1.7e-52
XP_016878594 (OMIM: 608947) PREDICTED: BTB/POZ dom ( 175) 559 139.8 4e-33
XP_016878595 (OMIM: 608947) PREDICTED: BTB/POZ dom ( 173) 552 138.1 1.2e-32
NP_001161433 (OMIM: 611725,611726) BTB/POZ domain- ( 288) 266 71.0 3.2e-12
NP_694578 (OMIM: 611725,611726) BTB/POZ domain-con ( 289) 266 71.0 3.2e-12
NP_001269615 (OMIM: 616386,616398) BTB/POZ domain- ( 220) 210 57.8 2.4e-08
NP_001269614 (OMIM: 616386,616398) BTB/POZ domain- ( 225) 210 57.8 2.4e-08
NP_076981 (OMIM: 615240) BTB/POZ domain-containing ( 234) 210 57.8 2.5e-08
XP_011528679 (OMIM: 616386,616398) PREDICTED: BTB/ ( 249) 210 57.8 2.6e-08
NP_001123467 (OMIM: 615240) BTB/POZ domain-contain ( 283) 210 57.8 2.9e-08
XP_011525599 (OMIM: 615240) PREDICTED: BTB/POZ dom ( 283) 210 57.8 2.9e-08
XP_011525600 (OMIM: 615240) PREDICTED: BTB/POZ dom ( 283) 210 57.8 2.9e-08
NP_001123466 (OMIM: 615240) BTB/POZ domain-contain ( 283) 210 57.8 2.9e-08
XP_016882772 (OMIM: 615240) PREDICTED: BTB/POZ dom ( 283) 210 57.8 2.9e-08
NP_078957 (OMIM: 616386,616398) BTB/POZ domain-con ( 297) 210 57.9 3e-08
XP_005261801 (OMIM: 616386,616398) PREDICTED: BTB/ ( 315) 210 57.9 3.2e-08
NP_001269613 (OMIM: 616386,616398) BTB/POZ domain- ( 321) 210 57.9 3.2e-08
XP_005261800 (OMIM: 616386,616398) PREDICTED: BTB/ ( 328) 210 57.9 3.3e-08
XP_005261798 (OMIM: 616386,616398) PREDICTED: BTB/ ( 352) 210 57.9 3.5e-08
XP_005261799 (OMIM: 616386,616398) PREDICTED: BTB/ ( 352) 210 57.9 3.5e-08
XP_011528676 (OMIM: 616386,616398) PREDICTED: BTB/ ( 370) 210 57.9 3.6e-08
NP_001245150 (OMIM: 181270,613420) BTB/POZ domain- ( 257) 194 54.1 3.6e-07
XP_016881197 (OMIM: 181270,613420) PREDICTED: BTB/ ( 257) 194 54.1 3.6e-07
NP_001129677 (OMIM: 181270,613420) BTB/POZ domain- ( 257) 194 54.1 3.6e-07
NP_945342 (OMIM: 181270,613420) BTB/POZ domain-con ( 257) 194 54.1 3.6e-07
NP_001245151 (OMIM: 181270,613420) BTB/POZ domain- ( 265) 194 54.1 3.7e-07
NP_061865 (OMIM: 611285) BTB/POZ domain-containing ( 234) 192 53.6 4.7e-07
NP_001136202 (OMIM: 181270,613420) BTB/POZ domain- ( 865) 194 54.4 1e-06
XP_011522877 (OMIM: 613422) PREDICTED: BTB/POZ dom ( 226) 187 52.4 1e-06
NP_056168 (OMIM: 613422) BTB/POZ domain-containing ( 263) 187 52.4 1.2e-06
XP_011535975 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 286) 184 51.7 2e-06
XP_011535974 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 304) 184 51.8 2.1e-06
XP_006714852 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 428) 184 51.8 2.8e-06
XP_005268549 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 428) 184 51.8 2.8e-06
XP_011535973 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 428) 184 51.8 2.8e-06
NP_065819 (OMIM: 613423) BTB/POZ domain-containing ( 428) 184 51.8 2.8e-06
XP_005268550 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 428) 184 51.8 2.8e-06
NP_612453 (OMIM: 610521) BTB/POZ domain-containing ( 325) 171 48.7 1.9e-05
NP_001306223 (OMIM: 613272) BTB/POZ domain-contain ( 813) 170 48.7 4.8e-05
NP_057205 (OMIM: 613272) BTB/POZ domain-containing ( 815) 170 48.7 4.8e-05
NP_955751 (OMIM: 607947) potassium channel regulat ( 229) 151 43.9 0.00036
NP_775876 (OMIM: 607947) potassium channel regulat ( 272) 151 44.0 0.00042
>>NP_114160 (OMIM: 613421) BTB/POZ domain-containing ada (313 aa)
initn: 2047 init1: 2047 opt: 2047 Z-score: 2601.7 bits: 489.6 E(85289): 3.5e-138
Smith-Waterman score: 2047; 100.0% identity (100.0% similar) in 313 aa overlap (1-313:1-313)
10 20 30 40 50 60
pF1KE3 MEEMSGESVVSSAVPAAATRTTSFKGTSPSSKYVKLNVGGALYYTTMQTLTKQDTMLKAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 MEEMSGESVVSSAVPAAATRTTSFKGTSPSSKYVKLNVGGALYYTTMQTLTKQDTMLKAM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 FSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 VEECQAALQNKDTYEPFCKVPVITSSKEEQKLIATSNKPAVKLLYNRSNNKYSYTSNSDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 VEECQAALQNKDTYEPFCKVPVITSSKEEQKLIATSNKPAVKLLYNRSNNKYSYTSNSDD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 NMLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKIAEVCCTSIVYATEKKQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 NMLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKIAEVCCTSIVYATEKKQT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 KVEFPEARIYEETLNILLYEAQDGRGPDNALLEATGGAAGRSHHLDEDEERERIERVRRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_114 KVEFPEARIYEETLNILLYEAQDGRGPDNALLEATGGAAGRSHHLDEDEERERIERVRRI
250 260 270 280 290 300
310
pF1KE3 HIKRPDDRAHLHQ
:::::::::::::
NP_114 HIKRPDDRAHLHQ
310
>>NP_001304324 (OMIM: 613421) BTB/POZ domain-containing (314 aa)
initn: 1233 init1: 1233 opt: 2035 Z-score: 2586.5 bits: 486.7 E(85289): 2.5e-137
Smith-Waterman score: 2035; 99.7% identity (99.7% similar) in 314 aa overlap (1-313:1-314)
10 20 30 40 50 60
pF1KE3 MEEMSGESVVSSAVPAAATRTTSFKGTSPSSKYVKLNVGGALYYTTMQTLTKQDTMLKAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEEMSGESVVSSAVPAAATRTTSFKGTSPSSKYVKLNVGGALYYTTMQTLTKQDTMLKAM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGL
70 80 90 100 110 120
130 140 150 160 170
pF1KE3 VEECQAALQ-NKDTYEPFCKVPVITSSKEEQKLIATSNKPAVKLLYNRSNNKYSYTSNSD
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEECQAALQQNKDTYEPFCKVPVITSSKEEQKLIATSNKPAVKLLYNRSNNKYSYTSNSD
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE3 DNMLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKIAEVCCTSIVYATEKKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNMLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKIAEVCCTSIVYATEKKQ
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE3 TKVEFPEARIYEETLNILLYEAQDGRGPDNALLEATGGAAGRSHHLDEDEERERIERVRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TKVEFPEARIYEETLNILLYEAQDGRGPDNALLEATGGAAGRSHHLDEDEERERIERVRR
250 260 270 280 290 300
300 310
pF1KE3 IHIKRPDDRAHLHQ
::::::::::::::
NP_001 IHIKRPDDRAHLHQ
310
>>NP_066960 (OMIM: 191161) BTB/POZ domain-containing ada (316 aa)
initn: 880 init1: 780 opt: 1452 Z-score: 1846.0 bits: 349.7 E(85289): 4.4e-96
Smith-Waterman score: 1452; 70.7% identity (88.2% similar) in 314 aa overlap (4-313:1-311)
10 20 30 40 50 60
pF1KE3 MEEMSGESVVSSAVPAAATRTTSFKGTSPSSKYVKLNVGGALYYTTMQTLTKQDTMLKAM
:::.. . : .: . ..::: . ..:::.:::::.:::::...::..:::::::
NP_066 MSGDTCLCPA-SGAKPKLSGFKGGGLGNKYVQLNVGGSLYYTTVRALTRHDTMLKAM
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 FSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGL
::::::::::.:::::::::::::::::::::: .. ::..:.::.::.:::::::.:::
NP_066 FSGRMEVLTDKEGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGL
60 70 80 90 100 110
130 140 150 160 170
pF1KE3 VEECQAALQNK-DTYEPFCKVPVITSSKEEQKLIATSNKPAVKLLYNRSNNKYSYTSNSD
:. ::.:::.: :.:.: :..:.::: :::..:: .:.::.:::::::::::::::::::
NP_066 VNMCQSALQDKKDSYQPVCNIPIITSLKEEERLIESSTKPVVKLLYNRSNNKYSYTSNSD
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 DNMLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKIAEVCCTSIVYATEKKQ
:..::::::::::::::::::::::::::::::::::::::::.::::::::::::::::
NP_066 DHLLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKLAEVCCTSIVYATEKKQ
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE3 TKVEFPEARIYEETLNILLYEAQDGRGPDNALLEATGGAAGRSHHLDEDEERERIERVRR
::::::::::::::::.::::. : :::.:::::. . ... ...: : .::::
NP_066 TKVEFPEARIYEETLNVLLYETP--RVPDNSLLEATSRSRSQASPSEDEETFELRDRVRR
240 250 260 270 280 290
300 310
pF1KE3 IHIKRP---DDRAHLHQ
::.:: ::: ::
NP_066 IHVKRYSTYDDRQLGHQSTHRD
300 310
>>NP_849194 (OMIM: 608947) BTB/POZ domain-containing ada (329 aa)
initn: 898 init1: 763 opt: 1418 Z-score: 1802.5 bits: 341.8 E(85289): 1.2e-93
Smith-Waterman score: 1418; 72.4% identity (89.8% similar) in 294 aa overlap (24-313:33-324)
10 20 30 40 50
pF1KE3 MEEMSGESVVSSAVPAAATRTTSFKGTSPSSKYVKLNVGGALYYTTMQTLTKQ
.: .:.::::::::::.:.:::..::: :
NP_849 AEASGPAAAAAPSLEAPKPSGLEPGPAAYGLKPLTPNSKYVKLNVGGSLHYTTLRTLTGQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 DTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAK
:::::::::::.:::::. ::.:::: :.::::::::::::.:::::: ::. :::.::.
NP_849 DTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESTRELGELLGEAR
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 YYLVQGLVEECQAALQNK-DTYEPFCKVPVITSSKEEQKLIATSNKPAVKLLYNRSNNKY
:::::::.:.:: :::.: .: :.: .:..:: .:::.:.:...::.::::.:::::::
NP_849 YYLVQGLIEDCQLALQQKRETLSPLCLIPMVTSPREEQQLLASTSKPVVKLLHNRSNNKY
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE3 SYTSNSDDNMLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKIAEVCCTSIV
::::.::::.::::::::::.:::.::.::.:::.:::::::::::::::::::::::::
NP_849 SYTSTSDDNLLKNIELFDKLALRFHGRLLFLKDVLGDEICCWSFYGQGRKIAEVCCTSIV
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE3 YATEKKQTKVEFPEARIYEETLNILLYEAQDGRGPDNALLEATGGAAGRSHHLDEDEERE
:::::::::::::::::.:::::::.::. :::: ::::::::::: . ..:..
NP_849 YATEKKQTKVEFPEARIFEETLNILIYETP--RGPDPALLEATGGAAGAGGAGRGEDEEN
250 260 270 280 290 300
300 310
pF1KE3 RIERVRRIHIKRP---DDRAHLHQ
: .::::::..: :.: : .:
NP_849 REHRVRRIHVRRHITHDERPHGQQIVFKD
310 320
>>XP_016880482 (OMIM: 191161) PREDICTED: BTB/POZ domain- (391 aa)
initn: 668 init1: 668 opt: 1234 Z-score: 1567.7 bits: 298.6 E(85289): 1.4e-80
Smith-Waterman score: 1234; 65.1% identity (82.6% similar) in 298 aa overlap (4-299:1-290)
10 20 30 40 50 60
pF1KE3 MEEMSGESVVSSAVPAAATRTTSFKGTSPSSKYVKLNVGGALYYTTMQTLTKQDTMLKAM
:::.. . : .: . ..::: . ..:::.:::::.:::::...::..:::::::
XP_016 MSGDTCLCPA-SGAKPKLSGFKGGGLGNKYVQLNVGGSLYYTTVRALTRHDTMLKAM
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 FSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGL
::::::::::.:::::::::::::::::::::: .. ::..:.::.::.:::::::.:::
XP_016 FSGRMEVLTDKEGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGL
60 70 80 90 100 110
130 140 150 160 170
pF1KE3 VEECQAALQNK-DTYEPFCKVPVITSSKEEQKLIATSNKPAVKLLYNRSNNKYSYTSNSD
:. ::.:::.: :.:.: :..:.::: :::..:: .:.::.:::::::::::::::::::
XP_016 VNMCQSALQDKKDSYQPVCNIPIITSLKEEERLIESSTKPVVKLLYNRSNNKYSYTSNSD
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 DNMLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKIAEVCCTSIVYATEKKQ
:..::::::::::::::::::::::::::::::::::::::::.::::::::::::::::
XP_016 DHLLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKLAEVCCTSIVYATEKKQ
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE3 TKVE-FPEARIYEETLNILLYEAQDGRGPDNALLEATGGAAGRSHHLDEDEERERIERVR
::: . : . :.: . ::: . : : . : . . .: : .:
XP_016 TKVWGIAPAWVGEDT-----HPLCGGRGRAVTSTEQKGHGLGSFFQTRWNSQRP--ESMR
240 250 260 270 280
300 310
pF1KE3 RIHIKRPDDRAHLHQ
:
XP_016 RHSTSYSMRLPASPTTPCWRPQAVAAARLPPVKMRRPLNCGTVSAASTSSATALTMTGSS
290 300 310 320 330 340
>>NP_001304328 (OMIM: 613421) BTB/POZ domain-containing (290 aa)
initn: 1885 init1: 1117 opt: 1120 Z-score: 1424.9 bits: 271.7 E(85289): 1.3e-72
Smith-Waterman score: 1843; 92.7% identity (92.7% similar) in 313 aa overlap (1-313:1-290)
10 20 30 40 50 60
pF1KE3 MEEMSGESVVSSAVPAAATRTTSFKGTSPSSKYVKLNVGGALYYTTMQTLTKQDTMLKAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEEMSGESVVSSAVPAAATRTTSFKGTSPSSKYVKLNVGGALYYTTMQTLTKQDTMLKAM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 VEECQAALQNKDTYEPFCKVPVITSSKEEQKLIATSNKPAVKLLYNRSNNKYSYTSNSDD
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEECQAALQNKDTYEPFCKVPVITSSKEEQKLIATSNKPAVKLLYNRSNNKYSYT-----
130 140 150 160 170
190 200 210 220 230 240
pF1KE3 NMLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKIAEVCCTSIVYATEKKQT
::::::::::::::::::::::::::::::::::::::::::
NP_001 ------------------RVLFIKDVIGDEICCWSFYGQGRKIAEVCCTSIVYATEKKQT
180 190 200 210
250 260 270 280 290 300
pF1KE3 KVEFPEARIYEETLNILLYEAQDGRGPDNALLEATGGAAGRSHHLDEDEERERIERVRRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVEFPEARIYEETLNILLYEAQDGRGPDNALLEATGGAAGRSHHLDEDEERERIERVRRI
220 230 240 250 260 270
310
pF1KE3 HIKRPDDRAHLHQ
:::::::::::::
NP_001 HIKRPDDRAHLHQ
280 290
>>XP_011544086 (OMIM: 608947) PREDICTED: BTB/POZ domain- (202 aa)
initn: 897 init1: 762 opt: 883 Z-score: 1126.3 bits: 215.9 E(85289): 5.4e-56
Smith-Waterman score: 883; 70.2% identity (88.8% similar) in 188 aa overlap (129-313:12-197)
100 110 120 130 140 150
pF1KE3 PESRREIEELLAEAKYYLVQGLVEECQAALQNKDTYEPFCKVPVITSSKEEQKLIATSNK
:...: :.: .:..:: .:::.:.:...:
XP_011 MPMFLGELPKQQKRETLSPLCLIPMVTSPREEQQLLASTSK
10 20 30 40
160 170 180 190 200 210
pF1KE3 PAVKLLYNRSNNKYSYTSNSDDNMLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYG
:.::::.:::::::::::.::::.::::::::::.:::.::.::.:::.:::::::::::
XP_011 PVVKLLHNRSNNKYSYTSTSDDNLLKNIELFDKLALRFHGRLLFLKDVLGDEICCWSFYG
50 60 70 80 90 100
220 230 240 250 260 270
pF1KE3 QGRKIAEVCCTSIVYATEKKQTKVEFPEARIYEETLNILLYEAQDGRGPDNALLEATGGA
:::::::::::::::::::::::::::::::.:::::::.::. :::: :::::::::
XP_011 QGRKIAEVCCTSIVYATEKKQTKVEFPEARIFEETLNILIYETP--RGPDPALLEATGGA
110 120 130 140 150
280 290 300 310
pF1KE3 AGRSHHLDEDEERERIERVRRIHIKRP---DDRAHLHQ
:: . ..:..: .::::::..: :.: : .:
XP_011 AGAGGAGRGEDEENREHRVRRIHVRRHITHDERPHGQQIVFKD
160 170 180 190 200
>>XP_011544085 (OMIM: 608947) PREDICTED: BTB/POZ domain- (347 aa)
initn: 897 init1: 762 opt: 883 Z-score: 1122.7 bits: 216.1 E(85289): 8.5e-56
Smith-Waterman score: 1379; 67.9% identity (84.6% similar) in 312 aa overlap (24-313:33-342)
10 20 30 40 50
pF1KE3 MEEMSGESVVSSAVPAAATRTTSFKGTSPSSKYVKLNVGGALYYTTMQTLTKQ
.: .:.::::::::::.:.:::..::: :
XP_011 AEASGPAAAAAPSLEAPKPSGLEPGPAAYGLKPLTPNSKYVKLNVGGSLHYTTLRTLTGQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 DTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAK
:::::::::::.:::::. ::.:::: :.::::::::::::.:::::: ::. :::.::.
XP_011 DTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESTRELGELLGEAR
70 80 90 100 110 120
120 130 140 150
pF1KE3 YYLVQGLVEECQAALQ-------------------NKDTYEPFCKVPVITSSKEEQKLIA
:::::::.:.:: ::: ...: :.: .:..:: .:::.:.:
XP_011 YYLVQGLIEDCQLALQVRAFGVPMPMFLGELPKQQKRETLSPLCLIPMVTSPREEQQLLA
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE3 TSNKPAVKLLYNRSNNKYSYTSNSDDNMLKNIELFDKLSLRFNGRVLFIKDVIGDEICCW
...::.::::.:::::::::::.::::.::::::::::.:::.::.::.:::.:::::::
XP_011 STSKPVVKLLHNRSNNKYSYTSTSDDNLLKNIELFDKLALRFHGRLLFLKDVLGDEICCW
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE3 SFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIYEETLNILLYEAQDGRGPDNALLEA
:::::::::::::::::::::::::::::::::::.:::::::.::. :::: :::::
XP_011 SFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIFEETLNILIYETP--RGPDPALLEA
250 260 270 280 290 300
280 290 300 310
pF1KE3 TGGAAGRSHHLDEDEERERIERVRRIHIKRP---DDRAHLHQ
:::::: . ..:..: .::::::..: :.: : .:
XP_011 TGGAAGAGGAGRGEDEENREHRVRRIHVRRHITHDERPHGQQIVFKD
310 320 330 340
>>XP_016878593 (OMIM: 608947) PREDICTED: BTB/POZ domain- (178 aa)
initn: 885 init1: 712 opt: 833 Z-score: 1063.6 bits: 204.1 E(85289): 1.7e-52
Smith-Waterman score: 833; 72.6% identity (89.7% similar) in 175 aa overlap (142-313:1-173)
120 130 140 150 160 170
pF1KE3 AKYYLVQGLVEECQAALQNKDTYEPFCKVPVITSSKEEQKLIATSNKPAVKLLYNRSNNK
..:: .:::.:.:...::.::::.::::::
XP_016 MVTSPREEQQLLASTSKPVVKLLHNRSNNK
10 20 30
180 190 200 210 220 230
pF1KE3 YSYTSNSDDNMLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKIAEVCCTSI
:::::.::::.::::::::::.:::.::.::.:::.::::::::::::::::::::::::
XP_016 YSYTSTSDDNLLKNIELFDKLALRFHGRLLFLKDVLGDEICCWSFYGQGRKIAEVCCTSI
40 50 60 70 80 90
240 250 260 270 280 290
pF1KE3 VYATEKKQTKVEFPEARIYEETLNILLYEAQDGRGPDNALLEATGGAAGRSHHLDEDEER
::::::::::::::::::.:::::::.::. :::: ::::::::::: . ..:.
XP_016 VYATEKKQTKVEFPEARIFEETLNILIYETP--RGPDPALLEATGGAAGAGGAGRGEDEE
100 110 120 130 140
300 310
pF1KE3 ERIERVRRIHIKRP---DDRAHLHQ
.: .::::::..: :.: : .:
XP_016 NREHRVRRIHVRRHITHDERPHGQQIVFKD
150 160 170
>>XP_016878594 (OMIM: 608947) PREDICTED: BTB/POZ domain- (175 aa)
initn: 538 init1: 538 opt: 559 Z-score: 715.7 bits: 139.8 E(85289): 4e-33
Smith-Waterman score: 559; 62.8% identity (84.7% similar) in 137 aa overlap (24-158:33-168)
10 20 30 40 50
pF1KE3 MEEMSGESVVSSAVPAAATRTTSFKGTSPSSKYVKLNVGGALYYTTMQTLTKQ
.: .:.::::::::::.:.:::..::: :
XP_016 AEASGPAAAAAPSLEAPKPSGLEPGPAAYGLKPLTPNSKYVKLNVGGSLHYTTLRTLTGQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 DTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAK
:::::::::::.:::::. ::.:::: :.::::::::::::.:::::: ::. :::.::.
XP_016 DTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESTRELGELLGEAR
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 YYLVQGLVEECQAALQNKDTYEPF--CKVPVITSSKEEQKLIATSNKPAVKLLYNRSNNK
:::::::.:.:: :::.. .: : :. :. . .. .. . :..
XP_016 YYLVQGLIEDCQLALQSR-AYSGFSSCSRNVFLQLVHQTRVQSRSSRCIWLSAS
130 140 150 160 170
180 190 200 210 220 230
pF1KE3 YSYTSNSDDNMLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKIAEVCCTSI
313 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 03:22:29 2016 done: Mon Nov 7 03:22:30 2016
Total Scan time: 7.480 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]