Result of FASTA (ccds) for
pFN21AE3121
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3121, 307 aa
1>>>pF1KE3121 307 - 307 aa - 307 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.9484+/-0.000713; mu= 13.9800+/- 0.043
mean_var=92.6245+/-18.550, 0's: 0 Z-trim(112.0): 11 B-trim: 283 in 1/51
Lambda= 0.133264
statistics sampled from 12811 (12820) to 12811 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.751), E-opt: 0.2 (0.394), width: 16
Scan time: 2.420
The best scores are: opt bits E(32554)
CCDS10805.2 TK2 gene_id:7084|Hs108|chr16 ( 265) 1840 363.2 1.2e-100
CCDS54018.1 TK2 gene_id:7084|Hs108|chr16 ( 234) 1521 301.8 3.3e-82
CCDS54016.1 TK2 gene_id:7084|Hs108|chr16 ( 240) 1290 257.4 7.8e-69
CCDS54017.1 TK2 gene_id:7084|Hs108|chr16 ( 247) 1162 232.8 2e-61
CCDS61955.1 TK2 gene_id:7084|Hs108|chr16 ( 168) 1149 230.2 8.5e-61
CCDS3548.1 DCK gene_id:1633|Hs108|chr4 ( 260) 321 71.1 1e-12
CCDS1931.1 DGUOK gene_id:1716|Hs108|chr2 ( 277) 289 65.0 7.5e-11
>>CCDS10805.2 TK2 gene_id:7084|Hs108|chr16 (265 aa)
initn: 1840 init1: 1840 opt: 1840 Z-score: 1920.1 bits: 363.2 E(32554): 1.2e-100
Smith-Waterman score: 1840; 100.0% identity (100.0% similar) in 265 aa overlap (43-307:1-265)
20 30 40 50 60 70
pF1KE3 SRRRPTAGLAVVRADSHKKEPRASGSARPAMLLWPLRGWAARALRCFGPGSRGSPASGPG
::::::::::::::::::::::::::::::
CCDS10 MLLWPLRGWAARALRCFGPGSRGSPASGPG
10 20 30
80 90 100 110 120 130
pF1KE3 PRRVQRRAWPPDKEQEKEKKSVICVEGNIASGKTTCLEFFSNATDVEVLTEPVSKWRNVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 PRRVQRRAWPPDKEQEKEKKSVICVEGNIASGKTTCLEFFSNATDVEVLTEPVSKWRNVR
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE3 GHNPLGLMYHDASRWGLTLQTYVQLTMLDRHTRPQVSSVRLMERSIHSARYIFVENLYRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 GHNPLGLMYHDASRWGLTLQTYVQLTMLDRHTRPQVSSVRLMERSIHSARYIFVENLYRS
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE3 GKMPEVDYVVLSEWFDWILRNMDVSVDLIVYLRTNPETCYQRLKKRCREEEKVIPLEYLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 GKMPEVDYVVLSEWFDWILRNMDVSVDLIVYLRTNPETCYQRLKKRCREEEKVIPLEYLE
160 170 180 190 200 210
260 270 280 290 300
pF1KE3 AIHHLHEEWLIKGSLFPMAAPVLVIEADHHMERMLELFEQNRDRILTPENRKHCP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 AIHHLHEEWLIKGSLFPMAAPVLVIEADHHMERMLELFEQNRDRILTPENRKHCP
220 230 240 250 260
>>CCDS54018.1 TK2 gene_id:7084|Hs108|chr16 (234 aa)
initn: 1521 init1: 1521 opt: 1521 Z-score: 1589.4 bits: 301.8 E(32554): 3.3e-82
Smith-Waterman score: 1521; 100.0% identity (100.0% similar) in 224 aa overlap (84-307:11-234)
60 70 80 90 100 110
pF1KE3 RALRCFGPGSRGSPASGPGPRRVQRRAWPPDKEQEKEKKSVICVEGNIASGKTTCLEFFS
::::::::::::::::::::::::::::::
CCDS54 MGAFCQRPSSDKEQEKEKKSVICVEGNIASGKTTCLEFFS
10 20 30 40
120 130 140 150 160 170
pF1KE3 NATDVEVLTEPVSKWRNVRGHNPLGLMYHDASRWGLTLQTYVQLTMLDRHTRPQVSSVRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 NATDVEVLTEPVSKWRNVRGHNPLGLMYHDASRWGLTLQTYVQLTMLDRHTRPQVSSVRL
50 60 70 80 90 100
180 190 200 210 220 230
pF1KE3 MERSIHSARYIFVENLYRSGKMPEVDYVVLSEWFDWILRNMDVSVDLIVYLRTNPETCYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MERSIHSARYIFVENLYRSGKMPEVDYVVLSEWFDWILRNMDVSVDLIVYLRTNPETCYQ
110 120 130 140 150 160
240 250 260 270 280 290
pF1KE3 RLKKRCREEEKVIPLEYLEAIHHLHEEWLIKGSLFPMAAPVLVIEADHHMERMLELFEQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 RLKKRCREEEKVIPLEYLEAIHHLHEEWLIKGSLFPMAAPVLVIEADHHMERMLELFEQN
170 180 190 200 210 220
300
pF1KE3 RDRILTPENRKHCP
::::::::::::::
CCDS54 RDRILTPENRKHCP
230
>>CCDS54016.1 TK2 gene_id:7084|Hs108|chr16 (240 aa)
initn: 1339 init1: 1290 opt: 1290 Z-score: 1349.2 bits: 257.4 E(32554): 7.8e-69
Smith-Waterman score: 1616; 90.6% identity (90.6% similar) in 265 aa overlap (43-307:1-240)
20 30 40 50 60 70
pF1KE3 SRRRPTAGLAVVRADSHKKEPRASGSARPAMLLWPLRGWAARALRCFGPGSRGSPASGPG
::::::::::::::::::::::::::::::
CCDS54 MLLWPLRGWAARALRCFGPGSRGSPASGPG
10 20 30
80 90 100 110 120 130
pF1KE3 PRRVQRRAWPPDKEQEKEKKSVICVEGNIASGKTTCLEFFSNATDVEVLTEPVSKWRNVR
:::::::::::::::::::::: :::::::::::::
CCDS54 PRRVQRRAWPPDKEQEKEKKSV-------------------------VLTEPVSKWRNVR
40 50 60
140 150 160 170 180 190
pF1KE3 GHNPLGLMYHDASRWGLTLQTYVQLTMLDRHTRPQVSSVRLMERSIHSARYIFVENLYRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 GHNPLGLMYHDASRWGLTLQTYVQLTMLDRHTRPQVSSVRLMERSIHSARYIFVENLYRS
70 80 90 100 110 120
200 210 220 230 240 250
pF1KE3 GKMPEVDYVVLSEWFDWILRNMDVSVDLIVYLRTNPETCYQRLKKRCREEEKVIPLEYLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 GKMPEVDYVVLSEWFDWILRNMDVSVDLIVYLRTNPETCYQRLKKRCREEEKVIPLEYLE
130 140 150 160 170 180
260 270 280 290 300
pF1KE3 AIHHLHEEWLIKGSLFPMAAPVLVIEADHHMERMLELFEQNRDRILTPENRKHCP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 AIHHLHEEWLIKGSLFPMAAPVLVIEADHHMERMLELFEQNRDRILTPENRKHCP
190 200 210 220 230 240
>>CCDS54017.1 TK2 gene_id:7084|Hs108|chr16 (247 aa)
initn: 1162 init1: 1162 opt: 1162 Z-score: 1216.1 bits: 232.8 E(32554): 2e-61
Smith-Waterman score: 1666; 93.2% identity (93.2% similar) in 265 aa overlap (43-307:1-247)
20 30 40 50 60 70
pF1KE3 SRRRPTAGLAVVRADSHKKEPRASGSARPAMLLWPLRGWAARALRCFGPGSRGSPASGPG
::::::::::::::::::::::::::::::
CCDS54 MLLWPLRGWAARALRCFGPGSRGSPASGPG
10 20 30
80 90 100 110 120 130
pF1KE3 PRRVQRRAWPPDKEQEKEKKSVICVEGNIASGKTTCLEFFSNATDVEVLTEPVSKWRNVR
:::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 PRRVQRRAWPPDKEQEKEKKSVICVEGNIASGKTTCLEFFSNATDVE-------------
40 50 60 70
140 150 160 170 180 190
pF1KE3 GHNPLGLMYHDASRWGLTLQTYVQLTMLDRHTRPQVSSVRLMERSIHSARYIFVENLYRS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 -----GLMYHDASRWGLTLQTYVQLTMLDRHTRPQVSSVRLMERSIHSARYIFVENLYRS
80 90 100 110 120 130
200 210 220 230 240 250
pF1KE3 GKMPEVDYVVLSEWFDWILRNMDVSVDLIVYLRTNPETCYQRLKKRCREEEKVIPLEYLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 GKMPEVDYVVLSEWFDWILRNMDVSVDLIVYLRTNPETCYQRLKKRCREEEKVIPLEYLE
140 150 160 170 180 190
260 270 280 290 300
pF1KE3 AIHHLHEEWLIKGSLFPMAAPVLVIEADHHMERMLELFEQNRDRILTPENRKHCP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 AIHHLHEEWLIKGSLFPMAAPVLVIEADHHMERMLELFEQNRDRILTPENRKHCP
200 210 220 230 240
>>CCDS61955.1 TK2 gene_id:7084|Hs108|chr16 (168 aa)
initn: 1149 init1: 1149 opt: 1149 Z-score: 1204.9 bits: 230.2 E(32554): 8.5e-61
Smith-Waterman score: 1149; 100.0% identity (100.0% similar) in 168 aa overlap (140-307:1-168)
110 120 130 140 150 160
pF1KE3 EFFSNATDVEVLTEPVSKWRNVRGHNPLGLMYHDASRWGLTLQTYVQLTMLDRHTRPQVS
::::::::::::::::::::::::::::::
CCDS61 MYHDASRWGLTLQTYVQLTMLDRHTRPQVS
10 20 30
170 180 190 200 210 220
pF1KE3 SVRLMERSIHSARYIFVENLYRSGKMPEVDYVVLSEWFDWILRNMDVSVDLIVYLRTNPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 SVRLMERSIHSARYIFVENLYRSGKMPEVDYVVLSEWFDWILRNMDVSVDLIVYLRTNPE
40 50 60 70 80 90
230 240 250 260 270 280
pF1KE3 TCYQRLKKRCREEEKVIPLEYLEAIHHLHEEWLIKGSLFPMAAPVLVIEADHHMERMLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 TCYQRLKKRCREEEKVIPLEYLEAIHHLHEEWLIKGSLFPMAAPVLVIEADHHMERMLEL
100 110 120 130 140 150
290 300
pF1KE3 FEQNRDRILTPENRKHCP
::::::::::::::::::
CCDS61 FEQNRDRILTPENRKHCP
160
>>CCDS3548.1 DCK gene_id:1633|Hs108|chr4 (260 aa)
initn: 436 init1: 169 opt: 321 Z-score: 341.9 bits: 71.1 E(32554): 1e-12
Smith-Waterman score: 447; 33.9% identity (64.2% similar) in 254 aa overlap (78-299:6-259)
50 60 70 80 90 100
pF1KE3 LRGWAARALRCFGPGSRGSPASGPGPRRVQRRAWPP-DKEQEKEKKSVICVEGNIASGKT
.:. : . .: . . : .:::::.::.
CCDS35 MATPPKRSCPSFSASSEGTRIKKISIEGNIAAGKS
10 20 30
110 120 130 140 150
pF1KE3 TCLEFFSN-ATDVEVLTEPVSKWRNVR---------------GHNPLGLMYHDASRWGLT
: ...... : ::. :::..: ::. : : : .::. ::..:
CCDS35 TFVNILKQLCEDWEVVPEPVARWCNVQSTQDEFEELTMSQKNGGNVLQMMYEKPERWSFT
40 50 60 70 80 90
160 170 180 190 200
pF1KE3 LQTYV-------QLTMLDRHTRPQVSSVRLMERSIHSARYIFVENLYRSGKMPEVDYVVL
.:::. ::. :. . . . : ..:::..: ::::. :::.: : :.....
CCDS35 FQTYACLSRIRAQLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYESECMNETEWTIY
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE3 SEWFDWILRNMDVSVDL--IVYLRTNPETCYQRLKKRCREEEKVIPLEYLEAIHHLHEEW
..: ::. .. :..: :.::...:::: .:. : :.::. ::::::: .:. :: :
CCDS35 QDWHDWMNNQFGQSLELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESW
160 170 180 190 200 210
270 280 290 300
pF1KE3 LIKGSL-----FPMAAPVLVIEADHHMERMLE-LFEQNRDRILTPENRKHCP
:.. .: . . .:.:...... .. : : :. .. . :
CCDS35 LLHRTLKTNFDYLQEVPILTLDVNEDFKDKYESLVEKVKEFLSTL
220 230 240 250 260
>>CCDS1931.1 DGUOK gene_id:1716|Hs108|chr2 (277 aa)
initn: 427 init1: 164 opt: 289 Z-score: 308.3 bits: 65.0 E(32554): 7.5e-11
Smith-Waterman score: 404; 33.8% identity (66.7% similar) in 213 aa overlap (95-280:41-253)
70 80 90 100 110 120
pF1KE3 GSPASGPGPRRVQRRAWPPDKEQEKEKKSVICVEGNIASGKTTCLEFFSNA-TDVEVLTE
. .::::: ::.: ....... . .: ::
CCDS19 LRAPFSSMAKSPLEGVSSSRGLHAGRGPRRLSIEGNIAVGKSTFVKLLTKTYPEWHVATE
20 30 40 50 60 70
130 140 150 160
pF1KE3 PVSKWRNVRGH------------NPLGLMYHDASRWGLTLQTYVQLTMLDRHTRP-----
::. :.:... : : .::.. .::. :.::. :. : . .:
CCDS19 PVATWQNIQAAGTQKACTAQSLGNLLDMMYREPARWSYTFQTFSFLSRLKVQLEPFPEKL
80 90 100 110 120 130
170 180 190 200 210 220
pF1KE3 -QVSS-VRLMERSIHSARYIFVENLYRSGKMPEVDYVVLSEWFDWILRNMDVSVDL--IV
:. . :...:::..: ::::..::...:.. .... . ..: ...: .. . : ..
CCDS19 LQARKPVQIFERSVYSDRYIFAKNLFENGSLSDIEWHIYQDWHSFLLWEFASRITLHGFI
140 150 160 170 180 190
230 240 250 260 270
pF1KE3 YLRTNPETCYQRLKKRCREEEKVIPLEYLEAIHHLHEEWLIKGSL---FP--MAAPVLVI
::...:..: .:: .: ::::: : : ::: .: :: :::. . : : ::::.
CCDS19 YLQASPQVCLKRLYQRAREEEKGIELAYLEQLHGQHEAWLIHKTTKLHFEALMNIPVLVL
200 210 220 230 240 250
280 290 300
pF1KE3 EADHHMERMLELFEQNRDRILTPENRKHCP
...
CCDS19 DVNDDFSEEVTKQEDLMREVNTFVKNL
260 270
307 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 03:27:55 2016 done: Sun Nov 6 03:27:56 2016
Total Scan time: 2.420 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]