Result of FASTA (ccds) for
pFN21AE3119
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3119, 293 aa
1>>>pF1KE3119 293 - 293 aa - 293 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0711+/-0.000731; mu= 15.9982+/- 0.044
mean_var=60.4732+/-11.944, 0's: 0 Z-trim(108.1): 32 B-trim: 0 in 0/49
Lambda= 0.164927
statistics sampled from 9972 (9998) to 9972 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.707), E-opt: 0.2 (0.307), width: 16
Scan time: 2.200
The best scores are: opt bits E(32554)
CCDS133.1 FBXO6 gene_id:26270|Hs108|chr1 ( 293) 2065 499.6 1.1e-141
CCDS132.1 FBXO44 gene_id:93611|Hs108|chr1 ( 255) 1352 329.9 1.2e-90
CCDS130.1 FBXO2 gene_id:26232|Hs108|chr1 ( 296) 895 221.2 7.2e-58
CCDS131.1 FBXO44 gene_id:93611|Hs108|chr1 ( 224) 692 172.9 2e-43
CCDS81261.1 FBXO44 gene_id:93611|Hs108|chr1 ( 256) 684 171.0 8.2e-43
CCDS12527.1 FBXO27 gene_id:126433|Hs108|chr19 ( 283) 676 169.1 3.4e-42
CCDS12526.1 FBXO17 gene_id:115290|Hs108|chr19 ( 278) 492 125.3 5e-29
CCDS12529.1 NCCRP1 gene_id:342897|Hs108|chr19 ( 275) 337 88.4 6.3e-18
>>CCDS133.1 FBXO6 gene_id:26270|Hs108|chr1 (293 aa)
initn: 2065 init1: 2065 opt: 2065 Z-score: 2657.0 bits: 499.6 E(32554): 1.1e-141
Smith-Waterman score: 2065; 100.0% identity (100.0% similar) in 293 aa overlap (1-293:1-293)
10 20 30 40 50 60
pF1KE3 MDAPHSKAALDSINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLMTLWKRKCLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 MDAPHSKAALDSINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLMTLWKRKCLR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 EGFITKDWDQPVADWKIFYFLRSLHRNLLRNPCAEEDMFAWQIDFNGGDRWKVESLPGAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 EGFITKDWDQPVADWKIFYFLRSLHRNLLRNPCAEEDMFAWQIDFNGGDRWKVESLPGAH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GTDFPDPKVKKYFVTSYEMCLKSQLVDLVAEGYWEELLDTFRPDIVVKDWFAARADCGCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 GTDFPDPKVKKYFVTSYEMCLKSQLVDLVAEGYWEELLDTFRPDIVVKDWFAARADCGCT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 YQLKVQLASADYFVLASFEPPPVTIQQWNNATWTEVSYTFSDYPRGVRYILFQHGGRDTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 YQLKVQLASADYFVLASFEPPPVTIQQWNNATWTEVSYTFSDYPRGVRYILFQHGGRDTQ
190 200 210 220 230 240
250 260 270 280 290
pF1KE3 YWAGWYGPRVTNSSIVVSPKMTRNQASSEAQPGQKHGQEEAAQSPYRAVVQIF
:::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 YWAGWYGPRVTNSSIVVSPKMTRNQASSEAQPGQKHGQEEAAQSPYRAVVQIF
250 260 270 280 290
>>CCDS132.1 FBXO44 gene_id:93611|Hs108|chr1 (255 aa)
initn: 1397 init1: 1346 opt: 1352 Z-score: 1741.1 bits: 329.9 E(32554): 1.2e-90
Smith-Waterman score: 1352; 75.1% identity (87.4% similar) in 253 aa overlap (9-261:2-254)
10 20 30 40 50 60
pF1KE3 MDAPHSKAALDSINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLMTLWKRKCLR
:. .::::::::::::::::::::::::::::::::::::::.:::::::::
CCDS13 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLR
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 EGFITKDWDQPVADWKIFYFLRSLHRNLLRNPCAEEDMFAWQIDFNGGDRWKVESLPGAH
:::::.:::::::::::::::::::::::.:::::: . :..: ::::.::::.: .
CCDS13 EGFITEDWDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQ
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 GTDFPDPKVKKYFVTSYEMCLKSQLVDLVAEGYWEELLDTFRPDIVVKDWFAARADCGCT
.::. .::::::::: :::::.::: ::::::::.:: :::: :::::::: :::
CCDS13 RKEFPNDQVKKYFVTSYYTCLKSQVVDLKAEGYWEELMDTTRPDIEVKDWFAARPDCGSK
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE3 YQLKVQLASADYFVLASFEPPPVTIQQWNNATWTEVSYTFSDYPRGVRYILFQHGGRDTQ
::: ::: :. . :..:.: :.:::: ..: : :::.:::.:: ::::: ::::: ::.
CCDS13 YQLCVQLLSSAHAPLGTFQPDPATIQQKSDAKWREVSHTFSNYPPGVRYIWFQHGGVDTH
180 190 200 210 220 230
250 260 270 280 290
pF1KE3 YWAGWYGPRVTNSSIVVSPKMTRNQASSEAQPGQKHGQEEAAQSPYRAVVQIF
:::::::::::::::...: .
CCDS13 YWAGWYGPRVTNSSITIGPPLP
240 250
>>CCDS130.1 FBXO2 gene_id:26232|Hs108|chr1 (296 aa)
initn: 835 init1: 299 opt: 895 Z-score: 1152.4 bits: 221.2 E(32554): 7.2e-58
Smith-Waterman score: 895; 50.2% identity (72.9% similar) in 255 aa overlap (8-259:42-296)
10 20 30
pF1KE3 MDAPHSKAALDSINELPENILLELFTHVPARQLLLNC
:: ..:::: .::.... .:: .:. :
CCDS13 QPEEASPEEQPEEASAEEERPEDQQEEEAAAAAAYLDELPEPLLLRVLAALPAAELVQAC
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE3 RLVCSLWRDLIDLMTLWKRKCLREGFITKDWDQPVAD-WKIFYFLRSLHRNLLRNPCAEE
:::: :..:.: :: :: .::.. . . : :. :::: . .::::::::.::
CCDS13 RLVCLRWKELVDGAPLWLLKCQQEGLVPEGGVEEERDHWQQFYFLSKRRRNLLRNPCGEE
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE3 DMFAWQIDFNGGDRWKVESLPGAHGTDFP-DPKVKKYFVTSYEMCLKSQLVDLVAEGYWE
:. .: .::: :.:: ::: :..: : .:::::..:.: : :.:..:: ::::::
CCDS13 DLEGWCDVEHGGDGWRVEELPGDSGVEFTHDESVKKYFASSFEWCRKAQVIDLQAEGYWE
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE3 ELLDTFRPDIVVKDWFAARADCGCTYQLKVQLASADYFVLASFEPPPVTI-QQWNNATWT
::::: .: ::::::...:.: :: :.: :.: : ::: : :.. :. ... :
CCDS13 ELLDTTQPAIVVKDWYSGRSDAGCLYELTVKLLSEHENVLAEFSSGQVAVPQDSDGGGWM
200 210 220 230 240 250
220 230 240 250 260 270
pF1KE3 EVSYTFSDYPRGVRYILFQHGGRDTQYWAGWYGPRVTNSSIVVSPKMTRNQASSEAQPGQ
:.:.::.:: :::.. :.:::.:. :: ::.: ::::::. : :
CCDS13 EISHTFTDYGPGVRFVRFEHGGQDSVYWKGWFGARVTNSSVWVEP
260 270 280 290
280 290
pF1KE3 KHGQEEAAQSPYRAVVQIF
>>CCDS131.1 FBXO44 gene_id:93611|Hs108|chr1 (224 aa)
initn: 686 init1: 686 opt: 692 Z-score: 893.2 bits: 172.9 E(32554): 2e-43
Smith-Waterman score: 692; 78.7% identity (91.0% similar) in 122 aa overlap (9-130:2-123)
10 20 30 40 50 60
pF1KE3 MDAPHSKAALDSINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLMTLWKRKCLR
:. .::::::::::::::::::::::::::::::::::::::.:::::::::
CCDS13 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLR
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 EGFITKDWDQPVADWKIFYFLRSLHRNLLRNPCAEEDMFAWQIDFNGGDRWKVESLPGAH
:::::.:::::::::::::::::::::::.:::::: . :..: ::::.::::.: .
CCDS13 EGFITEDWDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQ
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 GTDFPDPKVKKYFVTSYEMCLKSQLVDLVAEGYWEELLDTFRPDIVVKDWFAARADCGCT
.::. .:.
CCDS13 RKEFPNDQVRSQARLRVQVPAVRSAPVVRARASGDLPARPGDHPAEERCQVEGGLPHILQ
120 130 140 150 160 170
>>CCDS81261.1 FBXO44 gene_id:93611|Hs108|chr1 (256 aa)
initn: 700 init1: 678 opt: 684 Z-score: 882.1 bits: 171.0 E(32554): 8.2e-43
Smith-Waterman score: 684; 79.2% identity (90.8% similar) in 120 aa overlap (9-128:2-121)
10 20 30 40 50 60
pF1KE3 MDAPHSKAALDSINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLMTLWKRKCLR
:. .::::::::::::::::::::::::::::::::::::::.:::::::::
CCDS81 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLR
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 EGFITKDWDQPVADWKIFYFLRSLHRNLLRNPCAEEDMFAWQIDFNGGDRWKVESLPGAH
:::::.:::::::::::::::::::::::.:::::: . :..: ::::.::::.: .
CCDS81 EGFITEDWDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQ
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 GTDFPDPKVKKYFVTSYEMCLKSQLVDLVAEGYWEELLDTFRPDIVVKDWFAARADCGCT
.::. .
CCDS81 RKEFPNDQHLPQVPGGGPQGRRVLGGADGYHTAGHRGQGLVRSQARLRVQVPAVRSAPVV
120 130 140 150 160 170
>>CCDS12527.1 FBXO27 gene_id:126433|Hs108|chr19 (283 aa)
initn: 663 init1: 450 opt: 676 Z-score: 871.1 bits: 169.1 E(32554): 3.4e-42
Smith-Waterman score: 676; 40.4% identity (63.6% similar) in 272 aa overlap (4-262:18-283)
10 20 30 40
pF1KE3 MDAPHSKAALDSINELPENILLELFTHVPARQLLLNCRLVCSLWRD
:. . ::: ...:: ..:: ...::: : :: :: :: ::
CCDS12 MGASVSRGRAARVPAPEPEPEEALD-LSQLPPELLLVVLSHVPPRTLLGRCRQVCRGWRA
10 20 30 40 50
50 60 70 80 90
pF1KE3 LIDLMTLWKRKCLREG--------FITKDWDQPVADWKI-----FYFLRSLHRNLLRNPC
:.: ..:: :. .... ..:. . . : : . :::.::::
CCDS12 LVDGQALWLLILARDHGATGRALLHLARSCQSPARNARPCPLGRFCARRPIGRNLIRNPC
60 70 80 90 100 110
100 110 120 130 140 150
pF1KE3 AEEDMFAWQIDFNGGDRWKVESLPGAHGTDFPDPKVKKYFVTSYEMCLKSQLVDLVAEGY
..: . :... .::: : :: . : : . ::::. : :.:..:: ::
CCDS12 GQEGLRKWMVQ-HGGDGWVVEE----NRTTVPGAPSQTCFVTSFSWCCKKQVLDLEEEGL
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE3 WEELLDTFRPDIVVKDWFAARADCGCTYQLKVQLASADYFVLASFEPPPVTIQQWNNATW
: ::::. : .: :.::..:: : :: :.: ::: .:. :: .: : : :::: .
CCDS12 WPELLDSGRIEICVSDWWGARHDSGCMYRLLVQLLDANQTVLDKFSAVPDPIPQWNNNAC
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE3 TEVSYTFSDYPRGVRYILFQHGGRDTQYWAGWYGPRVTNSSIVVSPKMTRNQASSEAQPG
.:...::. :::.. :.: :.:::.::: :: ::::::..: ...
CCDS12 LHVTHVFSNIKMGVRFVSFEHRGQDTQFWAGHYGARVTNSSVIVRVRLS
240 250 260 270 280
280 290
pF1KE3 QKHGQEEAAQSPYRAVVQIF
>>CCDS12526.1 FBXO17 gene_id:115290|Hs108|chr19 (278 aa)
initn: 571 init1: 409 opt: 492 Z-score: 634.6 bits: 125.3 E(32554): 5e-29
Smith-Waterman score: 601; 36.7% identity (63.3% similar) in 267 aa overlap (12-262:17-278)
10 20 30 40 50
pF1KE3 MDAPHSKAALDSINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLMTLWK
... :: ..:.....::: :.:. :: :: :::..: :.:
CCDS12 MGARLSRRRLPADPSLALDALPPELLVQVLSHVPPRSLVTRCRPVCRAWRDIVDGPTVWL
10 20 30 40 50 60
60 70 80 90
pF1KE3 RKCLR----EGFITKDWDQ---PVA-DWKIF-------YFLRS-LHRNLLRNPCAEEDMF
. : :: : : : . : : ::. . :::. : :.:. .
CCDS12 LQLARDRSAEGRALYAVAQRCLPSNEDKEEFPLCALARYCLRAPFGRNLIFNSCGEQGFR
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE3 AWQIDFNGGDRWKVESLPGAHGTDFPDPKVKKYFVTSYEMCLKSQLVDLVAEGYWEELLD
.:... .::. : .:. . : : . ::::.: : : :::::: :: :.::::
CCDS12 GWEVE-HGGNGWAIEK----NLTPVPGAPSQTCFVTSFEWCSKRQLVDLVMEGVWQELLD
130 140 150 160 170
160 170 180 190 200 210
pF1KE3 TFRPDIVVKDWFAARADCGCTYQLKVQLASADYFVLASFEPPPVTIQQWNNATWTEVSYT
. . .: : ::..:: .:::.:::.:.: .. ...: : . ::.. .::..
CCDS12 SAQIEICVADWWGARENCGCVYQLRVRLLDVYEKEVVKFSASPDPVLQWTERGCRQVSHV
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE3 FSDYPRGVRYILFQHGGRDTQYWAGWYGPRVTNSSIVVSPKMTRNQASSEAQPGQKHGQE
:... .:.::. :.. :::.. :.: :: ::.::. : ...
CCDS12 FTNFGKGIRYVSFEQYGRDVSSWVGHYGALVTHSSVRVRIRLS
240 250 260 270
280 290
pF1KE3 EAAQSPYRAVVQIF
>>CCDS12529.1 NCCRP1 gene_id:342897|Hs108|chr19 (275 aa)
initn: 340 init1: 173 opt: 337 Z-score: 435.4 bits: 88.4 E(32554): 6.3e-18
Smith-Waterman score: 337; 36.2% identity (60.5% similar) in 185 aa overlap (75-257:92-271)
50 60 70 80 90 100
pF1KE3 RDLIDLMTLWKRKCLREGFITKDWDQPVADWKIFYFLRSLHRNLLRNPCAEEDMFAWQID
::.. . : :.:::::.: : .
CCDS12 AQPSEAHARQLLLEEWGPLSGGLELPQRLTWKLLLLRRPLYRNLLRSPNPEGINIYEPAP
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 FNGGDRWKVESLPGAHGTDFPDPKVKKYFVTSYEMCLKSQLVDLVAEGYWEELLDTFRPD
.: . .:.: . .: . :... . .:.: :::.::: :::::: .:
CCDS12 PTGPTQRPLETLGNFRGWYIRTEKLQQ----NQSWTVKQQCVDLLAEGLWEELLDDEQPA
130 140 150 160 170
170 180 190 200 210 220
pF1KE3 IVVKDWFA-ARADCGCTYQLKVQLASADY-FVLASFEPPPVTIQQWNNATWTEVSYTFSD
:.: ::: .: : .:.:.:.: : .:: :.:. . : : . . :..::..:
CCDS12 ITVMDWFEDSRLD-ACVYELHVWLLAADRRTVIAQHHVAPRTSGRGPPGRWVQVSHVFRH
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE3 YPRGVRYILFQHGGRDTQYWAGWYGPRVTNSSIVVSPKMTRNQASSEAQPGQKHGQEEAA
: :::.: : : ... . .: :::.::. :
CCDS12 YGPGVRFIHFLHKAKNRMEPGGLRRTRVTDSSVSVQLRE
240 250 260 270
290
pF1KE3 QSPYRAVVQIF
293 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 19:30:49 2016 done: Sun Nov 6 19:30:49 2016
Total Scan time: 2.200 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]