FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE3113, 286 aa
  1>>>pF1KE3113 286 - 286 aa - 286 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.0474+/-0.00101; mu= 9.1442+/- 0.061
 mean_var=182.2006+/-37.461, 0's: 0 Z-trim(111.2): 24  B-trim: 0 in 0/52
 Lambda= 0.095017
 statistics sampled from 12149 (12161) to 12149 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.715), E-opt: 0.2 (0.374), width:  16
 Scan time:  2.220

The best scores are:                                      opt bits E(32554)
CCDS46985.1 FBXO45 gene_id:200933|Hs108|chr3       ( 286) 1974 282.5 2.5e-76
CCDS8567.1 SPSB2 gene_id:84727|Hs108|chr12         ( 263)  540 85.8 3.5e-17
CCDS3115.1 SPSB4 gene_id:92369|Hs108|chr3          ( 273)  516 82.6 3.5e-16
CCDS102.1 SPSB1 gene_id:80176|Hs108|chr1           ( 273)  490 79.0 4.2e-15


>>CCDS46985.1 FBXO45 gene_id:200933|Hs108|chr3            (286 aa)
 initn: 1974 init1: 1974 opt: 1974  Z-score: 1483.8  bits: 282.5 E(32554): 2.5e-76
Smith-Waterman score: 1974; 100.0% identity (100.0% similar) in 286 aa overlap (1-286:1-286)

               10        20        30        40        50        60
pF1KE3 MAAPAPGAGAASGGAGCSGGGAGAGAGSGSGAAGAGGRLPSRVLELVFSYLELSELRSCA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 MAAPAPGAGAASGGAGCSGGGAGAGAGSGSGAAGAGGRLPSRVLELVFSYLELSELRSCA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE3 LVCKHWYRCLHGDENSEVWRSLCARSLAEEALRTDILCNLPSYKAKIRAFQHAFSTNDCS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 LVCKHWYRCLHGDENSEVWRSLCARSLAEEALRTDILCNLPSYKAKIRAFQHAFSTNDCS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE3 RNVYIKKNGFTLHRNPIAQSTDGARTKIGFSEGRHAWEVWWEGPLGTVAVIGIATKRAPM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 RNVYIKKNGFTLHRNPIAQSTDGARTKIGFSEGRHAWEVWWEGPLGTVAVIGIATKRAPM
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE3 QCQGYVALLGSDDQSWGWNLVDNNLLHNGEVNGSFPQCNNAPKYQIGERIRVILDMEDKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 QCQGYVALLGSDDQSWGWNLVDNNLLHNGEVNGSFPQCNNAPKYQIGERIRVILDMEDKT
              190       200       210       220       230       240

              250       260       270       280      
pF1KE3 LAFERGYEFLGVAFRGLPKVCLYPAVSAVYGNTEVTLVYLGKPLDG
       ::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 LAFERGYEFLGVAFRGLPKVCLYPAVSAVYGNTEVTLVYLGKPLDG
              250       260       270       280      

>>CCDS8567.1 SPSB2 gene_id:84727|Hs108|chr12              (263 aa)
 initn: 515 init1: 209 opt: 540  Z-score: 421.9  bits: 85.8 E(32554): 3.5e-17
Smith-Waterman score: 540; 46.3% identity (75.1% similar) in 177 aa overlap (111-282:45-219)

               90       100       110       120       130       140
pF1KE3 SLCARSLAEEALRTDILCNLPSYKAKIRAFQHAFSTNDCSRNVYIKKNGFTLHRNPIAQS
                                     .:... .:::.:. .:..:. ..: :.:::
CCDS85 TPQALYPDLSCPEGLEELLSAPPPDLGAQRRHGWNPKDCSENIEVKEGGLYFERRPVAQS
           20        30        40        50        60        70    

              150       160          170       180       190       
pF1KE3 TDGARTKIGFSEGRHAWEVWWEGPL---GTVAVIGIATKRAPMQCQGYVALLGSDDQSWG
       ::::: : :.:.: ::::. :  ::   :: ::.:.::  ::.: . :.:::::...:::
CCDS85 TDGARGKRGYSRGLHAWEISW--PLEQRGTHAVVGVATALAPLQTDHYAALLGSNSESWG
           80        90         100       110       120       130  

       200       210         220       230       240       250     
pF1KE3 WNLVDNNLLHNGEVNGS--FPQCNNAPKYQIGERIRVILDMEDKTLAFERGYEFLGVAFR
       :..  ..: :...  :.  .:  ... . .. ::. :.::::. ::..  :  .:: :::
CCDS85 WDIGRGKLYHQSKGPGAPQYPAGTQGEQLEVPERLLVVLDMEEGTLGYAIGGTYLGPAFR
            140       150       160       170       180       190  

         260       270       280                                   
pF1KE3 GLPKVCLYPAVSAVYGNTEVTLVYLGKPLDG                             
       ::    ::::::::.:. .: . :::.                                 
CCDS85 GLKGRTLYPAVSAVWGQCQVRIRYLGERRAEPHSLLHLSRLCVRHNLGDTRLGQVSALPL
            200       210       220       230       240       250  

>>CCDS3115.1 SPSB4 gene_id:92369|Hs108|chr3               (273 aa)
 initn: 460 init1: 164 opt: 516  Z-score: 403.9  bits: 82.6 E(32554): 3.5e-16
Smith-Waterman score: 516; 42.5% identity (70.5% similar) in 193 aa overlap (93-280:36-227)

             70        80        90       100       110       120  
pF1KE3 CKHWYRCLHGDENSEVWRSLCARSLAEEALRTDILCNLPSYKAKIRAFQHAFSTNDCSRN
                                     : : : ..:.    .. ..::.. .: : :
CCDS31 SGSLKSVEVREPALRPAKRELRGAEPGRPARLDQLLDMPAAGLAVQ-LRHAWNPEDRSLN
          10        20        30        40        50         60    

             130       140       150       160        170       180
pF1KE3 VYIKKNG-FTLHRNPIAQSTDGARTKIGFSEGRHAWEVWWEG-PLGTVAVIGIATKRAPM
       :..: .  .:.::.:.:::::: : :.: ..: :::.. : .   :: ::.:.:: :::.
CCDS31 VFVKDDDRLTFHRHPVAQSTDGIRGKVGHARGLHAWQINWPARQRGTHAVVGVATARAPL
           70        80        90       100       110       120    

              190       200       210         220        230       
pF1KE3 QCQGYVALLGSDDQSWGWNLVDNNLLHNGEVNG--SFPQCNNAPK-YQIGERIRVILDME
       .  ::.::.::: .::::.:  . : :.:. .   ..:   .  . . . . . :.:::.
CCDS31 HSVGYTALVGSDAESWGWDLGRSRLYHDGKNQPGVAYPAFLGPDEAFALPDSLLVVLDMD
          130       140       150       160       170       180    

       240       250       260       270       280                 
pF1KE3 DKTLAFERGYEFLGVAFRGLPKVCLYPAVSAVYGNTEVTLVYLGKPLDG           
       . ::.:    ..::::::::    :::.::::.:. :::. :.                 
CCDS31 EGTLSFIVDGQYLGVAFRGLKGKKLYPVVSAVWGHCEVTMRYINGLDPEPLPLMDLCRRS
          190       200       210       220       230       240    

CCDS31 IRSALGRQRLQDISSLPLPQSLKNYLQYQ
          250       260       270   

>>CCDS102.1 SPSB1 gene_id:80176|Hs108|chr1                (273 aa)
 initn: 441 init1: 162 opt: 490  Z-score: 384.6  bits: 79.0 E(32554): 4.2e-15
Smith-Waterman score: 490; 39.4% identity (69.4% similar) in 193 aa overlap (93-280:36-227)

             70        80        90       100       110       120  
pF1KE3 CKHWYRCLHGDENSEVWRSLCARSLAEEALRTDILCNLPSYKAKIRAFQHAFSTNDCSRN
                                     : :.: ..:  .  .. . :....:: : :
CCDS10 TGGIKTVDMRDPTYRPLKQELQGLDYCKPTRLDLLLDMPPVSYDVQ-LLHSWNNNDRSLN
          10        20        30        40        50         60    

             130       140       150       160        170       180
pF1KE3 VYIKKNG-FTLHRNPIAQSTDGARTKIGFSEGRHAWEVWWEG-PLGTVAVIGIATKRAPM
       :..:..  . .::.:.:::::. : :.:...: :.:.. :     :: ::.:.::  ::.
CCDS10 VFVKEDDKLIFHRHPVAQSTDAIRGKVGYTRGLHVWQITWAMRQRGTHAVVGVATADAPL
           70        80        90       100       110       120    

              190       200       210         220        230       
pF1KE3 QCQGYVALLGSDDQSWGWNLVDNNLLHNGEVNGS--FPQCNNAPK-YQIGERIRVILDME
       .  ::..:.:.. .::::.:  : : :.:. . :  .:   .  . . . . . : :::.
CCDS10 HSVGYTTLVGNNHESWGWDLGRNRLYHDGKNQPSKTYPAFLEPDETFIVPDSFLVALDMD
          130       140       150       160       170       180    

       240       250       260       270       280                 
pF1KE3 DKTLAFERGYEFLGVAFRGLPKVCLYPAVSAVYGNTEVTLVYLGKPLDG           
       : ::.:    ...:::::::    :::.::::.:. :. . ::                 
CCDS10 DGTLSFIVDGQYMGVAFRGLKGKKLYPVVSAVWGHCEIRMRYLNGLDPEPLPLMDLCRRS
          190       200       210       220       230       240    

CCDS10 VRLALGRERLGEIHTLPLPASLKAYLLYQ
          250       260       270   




286 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 10:30:06 2016 done: Sun Nov  6 10:30:07 2016
 Total Scan time:  2.220 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]