Result of FASTA (omim) for
pFN21AE3055
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3055, 208 aa
1>>>pF1KE3055 208 - 208 aa - 208 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.9850+/-0.000382; mu= 10.0815+/- 0.024
mean_var=78.1207+/-15.608, 0's: 0 Z-trim(112.8): 18 B-trim: 64 in 1/50
Lambda= 0.145108
statistics sampled from 21864 (21881) to 21864 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.65), E-opt: 0.2 (0.257), width: 16
Scan time: 6.180
The best scores are: opt bits E(85289)
NP_795372 (OMIM: 615223) interferon epsilon precur ( 208) 1352 292.4 3.4e-79
NP_076918 (OMIM: 147660) interferon alpha-1/13 pre ( 189) 383 89.6 3.7e-18
NP_002167 (OMIM: 147640) interferon beta precursor ( 187) 380 88.9 5.6e-18
NP_008831 (OMIM: 147578) interferon alpha-1/13 pre ( 190) 378 88.5 7.6e-18
NP_002163 (OMIM: 147579) interferon alpha-14 precu ( 189) 376 88.1 1e-17
NP_002168 (OMIM: 147553) interferon omega-1 precur ( 195) 368 86.4 3.3e-17
NP_002162 (OMIM: 147577) interferon alpha-10 precu ( 189) 361 85.0 8.9e-17
NP_067091 (OMIM: 147583) interferon alpha-17 precu ( 189) 360 84.7 1e-16
NP_002160 (OMIM: 147565) interferon alpha-5 precur ( 189) 357 84.1 1.6e-16
NP_066546 (OMIM: 147564) interferon alpha-4 precur ( 189) 357 84.1 1.6e-16
NP_066401 (OMIM: 147567) interferon alpha-7 precur ( 189) 355 83.7 2.1e-16
NP_002161 (OMIM: 147568) interferon alpha-8 precur ( 189) 349 82.4 5.1e-16
NP_000596 (OMIM: 147562) interferon alpha-2 precur ( 188) 345 81.6 9.1e-16
NP_066282 (OMIM: 147566) interferon alpha-6 precur ( 189) 345 81.6 9.1e-16
NP_002166 (OMIM: 147584) interferon alpha-21 precu ( 189) 342 81.0 1.4e-15
NP_002164 (OMIM: 147580) interferon alpha-16 precu ( 189) 340 80.6 1.9e-15
NP_064509 (OMIM: 615326) interferon kappa precurso ( 207) 162 43.3 0.00034
>>NP_795372 (OMIM: 615223) interferon epsilon precursor (208 aa)
initn: 1352 init1: 1352 opt: 1352 Z-score: 1542.7 bits: 292.4 E(85289): 3.4e-79
Smith-Waterman score: 1352; 100.0% identity (100.0% similar) in 208 aa overlap (1-208:1-208)
10 20 30 40 50 60
pF1KE3 MIIKHFFGTVLVLLASTTIFSLDLKLIIFQQRQVNQESLKLLNKLQTLSIQQCLPHRKNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_795 MIIKHFFGTVLVLLASTTIFSLDLKLIIFQQRQVNQESLKLLNKLQTLSIQQCLPHRKNF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 LLPQKSLSPQQYQKGHTLAILHEMLQQIFSLFRANISLDGWEENHTEKFLIQLHQQLEYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_795 LLPQKSLSPQQYQKGHTLAILHEMLQQIFSLFRANISLDGWEENHTEKFLIQLHQQLEYL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 EALMGLEAEKLSGTLGSDNLRLQVKMYFRRIHDYLENQDYSTCAWAIVQVEISRCLFFVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_795 EALMGLEAEKLSGTLGSDNLRLQVKMYFRRIHDYLENQDYSTCAWAIVQVEISRCLFFVF
130 140 150 160 170 180
190 200
pF1KE3 SLTEKLSKQGRPLNDMKQELTTEFRSPR
::::::::::::::::::::::::::::
NP_795 SLTEKLSKQGRPLNDMKQELTTEFRSPR
190 200
>>NP_076918 (OMIM: 147660) interferon alpha-1/13 precurs (189 aa)
initn: 340 init1: 340 opt: 383 Z-score: 447.0 bits: 89.6 E(85289): 3.7e-18
Smith-Waterman score: 383; 37.4% identity (70.9% similar) in 182 aa overlap (10-189:10-188)
10 20 30 40 50 60
pF1KE3 MIIKHFFGTVLVLLASTTIFSLDLKLIIFQQRQVNQESLKLLNKLQTLSIQQCLPHRKNF
:::.:. . :: : .. . :...: :: ... .: ..:: :..:
NP_076 MASPFALLMVLVVLSCKSSCSLGCDLPETHSLD-NRRTLMLLAQMSRISPSSCLMDRHDF
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 LLPQKSLSPQQYQKGHTLAILHEMLQQIFSLFRANISLDGWEENHTEKFLIQLHQQLEYL
.::. .. .:.::. ....:::..::::.:: .. : .:.:. .:: .:.:::. :
NP_076 GFPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDL
60 70 80 90 100 110
130 140 150 160 170
pF1KE3 EALMGLEAEKLSGT--LGSDNLRLQVKMYFRRIHDYLENQDYSTCAWAIVQVEISRCLFF
:: . .. :... : ...:.. : :: ::::: :: .. :: ::: .:..:: : : .
NP_076 EACV-MQEERVGETPLMNADSI-LAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSL
120 130 140 150 160 170
180 190 200
pF1KE3 VFSLTEKLSKQGRPLNDMKQELTTEFRSPR
.: :.: ..
NP_076 STNLQERLRRKE
180
>>NP_002167 (OMIM: 147640) interferon beta precursor [Ho (187 aa)
initn: 370 init1: 320 opt: 380 Z-score: 443.7 bits: 88.9 E(85289): 5.6e-18
Smith-Waterman score: 380; 37.2% identity (68.3% similar) in 183 aa overlap (1-183:1-182)
10 20 30 40 50 60
pF1KE3 MIIKHFFGTVLVLLASTTIFSLDLKLIIFQQRQVNQESLKLLNKLQTLSIQQCLPHRKNF
: : .. .:.: ::: .:.. .:. : ::. : . ::: .:. .. :: : ::
NP_002 MTNKCLLQIALLLCFSTTALSMSYNLLGFLQRSSNFQCQKLLWQLNG-RLEYCLKDRMNF
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 LLPQKSLSPQQYQKGHTLAILHEMLQQIFSLFRANISLDGWEENHTEKFLIQLHQQLEYL
.:.. . ::.:: . ..::::.::..:: . : ::.:. .:..: ....:...:
NP_002 DIPEEIKQLQQFQKEDAALTIYEMLQNIFAIFRQDSSSTGWNETIVENLLANVYHQINHL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 EALMGLEAEKLSGTLGSDNLRLQVKMYFRRIHDYLENQDYSTCAWAIVQVEISRCLFFVF
.... . :: . : :. :..: :. :: ::. ..:: :::.::.::: : ..:.
NP_002 KTVLEEKLEKEDFTRGKLMSSLHLKRYYGRILHYLKAKEYSHCAWTIVRVEILRNFYFIN
120 130 140 150 160 170
190 200
pF1KE3 SLTEKLSKQGRPLNDMKQELTTEFRSPR
::
NP_002 RLTGYLRN
180
>>NP_008831 (OMIM: 147578) interferon alpha-1/13 precurs (190 aa)
initn: 340 init1: 340 opt: 378 Z-score: 441.3 bits: 88.5 E(85289): 7.6e-18
Smith-Waterman score: 378; 38.9% identity (73.9% similar) in 157 aa overlap (35-189:35-189)
10 20 30 40 50 60
pF1KE3 HFFGTVLVLLASTTIFSLDLKLIIFQQRQVNQESLKLLNKLQTLSIQQCLPHRKNFLLPQ
:...: :: ... .: ..:: :..: .::
NP_008 PFALLMALVVLSCKSSCSLGCDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDFGFPQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 KSLSPQQYQKGHTLAILHEMLQQIFSLFRANISLDGWEENHTEKFLIQLHQQLEYLEALM
. .. .:.::. ....:::..::::.:: .. : .:.:. .:: .:.:::. ::: .
NP_008 EEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDLEACV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GLEAEKLSGT--LGSDNLRLQVKMYFRRIHDYLENQDYSTCAWAIVQVEISRCLFFVFSL
.. :... : ...:.. : :: ::::: :: .. :: ::: .:..:: : : . .:
NP_008 -MQEERVGETPLMNADSI-LAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLSTNL
130 140 150 160 170 180
190 200
pF1KE3 TEKLSKQGRPLNDMKQELTTEFRSPR
:.: ..
NP_008 QERLRRKE
190
>>NP_002163 (OMIM: 147579) interferon alpha-14 precursor (189 aa)
initn: 347 init1: 347 opt: 376 Z-score: 439.1 bits: 88.1 E(85289): 1e-17
Smith-Waterman score: 376; 34.8% identity (67.9% similar) in 184 aa overlap (7-189:5-188)
10 20 30 40 50
pF1KE3 MIIKHFFGTVLVLLASTTIFSLDLKLIIFQQRQVN-QESLKLLNKLQTLSIQQCLPHRKN
:. ...:.. . : .: . : ...: ...: :. ... .: .:: :..
NP_002 MALPFALMMALVVLSCKSSCSLGCNLSQTHSLNNRRTLMLMAQMRRISPFSCLKDRHD
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 FLLPQKSLSPQQYQKGHTLAILHEMLQQIFSLFRANISLDGWEENHTEKFLIQLHQQLEY
: .::. .. .:.::......::::.:: :.:: .. : .:.:. ::: :.: ::..
NP_002 FEFPQEEFDGNQFQKAQAISVLHEMMQQTFNLFSTKNSSAAWDETLLEKFYIELFQQMND
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE3 LEALMGLEAEKLSGTLGSDNLRLQVKMYFRRIHDYLENQDYSTCAWAIVQVEISRCLFFV
::: . :. : ... : :: ::.:: :: .. :: ::: .:..:: : : :
NP_002 LEACVIQEVGVEETPLMNEDSILAVKKYFQRITLYLMEKKYSPCAWEVVRAEIMRSLSFS
120 130 140 150 160 170
180 190 200
pF1KE3 FSLTEKLSKQGRPLNDMKQELTTEFRSPR
.: ..: ..
NP_002 TNLQKRLRRKD
180
>>NP_002168 (OMIM: 147553) interferon omega-1 precursor (195 aa)
initn: 389 init1: 344 opt: 368 Z-score: 429.9 bits: 86.4 E(85289): 3.3e-17
Smith-Waterman score: 368; 35.7% identity (69.2% similar) in 185 aa overlap (11-193:11-192)
10 20 30 40 50 60
pF1KE3 MIIKHFFGTVLVLLASTTIFSLDLKLIIFQQRQVNQESLKLLNKLQTLSIQQCLPHRKNF
::. . . . :: : .. .....: ::.... .: :: :..:
NP_002 MALLFPLLAALVMTSYSPVGSLGCDLPQ-NHGLLSRNTLVLLHQMRRISPFLCLKDRRDF
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 LLPQKSLSPQQYQKGHTLAILHEMLQQIFSLFRANISLDGWEENHTEKFLIQLHQQLEYL
.::. .. .: ::.:....::::::::::::... : .:. . ... :::::..:
NP_002 RFPQEMVKGSQLQKAHVMSVLHEMLQQIFSLFHTERSSAAWNMTLLDQLHTGLHQQLQHL
60 70 80 90 100 110
130 140 150 160 170
pF1KE3 EA-LMGLEAEKLS-GTLGSDNLRLQVKMYFRRIHDYLENQDYSTCAWAIVQVEISRCLFF
:. :. . .: : :...: : : . ::. :. ::... :: ::: .:..:: . ::.
NP_002 ETCLLQVVGEGESAGAISSPALTL--RRYFQGIRVYLKEKKYSDCAWEVVRMEIMKSLFL
120 130 140 150 160 170
180 190 200
pF1KE3 VFSLTEKLSKQGRPLNDMKQELTTEFRSPR
.. :.: .. : :
NP_002 STNMQERLRSKDRDLGSS
180 190
>>NP_002162 (OMIM: 147577) interferon alpha-10 precursor (189 aa)
initn: 365 init1: 350 opt: 361 Z-score: 422.1 bits: 85.0 E(85289): 8.9e-17
Smith-Waterman score: 361; 38.1% identity (69.7% similar) in 155 aa overlap (35-189:34-188)
10 20 30 40 50 60
pF1KE3 HFFGTVLVLLASTTIFSLDLKLIIFQQRQVNQESLKLLNKLQTLSIQQCLPHRKNFLLPQ
:...: ::... .: .:: :..: .::
NP_002 SFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLGQMGRISPFSCLKDRHDFRIPQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 KSLSPQQYQKGHTLAILHEMLQQIFSLFRANISLDGWEENHTEKFLIQLHQQLEYLEALM
. .. .:.::......::::.:: :.:: .. : .::.. ::: .:.:::. ::: .
NP_002 EEFDGNQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLEACV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GLEAEKLSGTLGSDNLRLQVKMYFRRIHDYLENQDYSTCAWAIVQVEISRCLFFVFSLTE
:. : ... : :. ::.:: :: .. :: ::: .:..:: : : : .: .
NP_002 IQEVGVEETPLMNEDSILAVRKYFQRITLYLIERKYSPCAWEVVRAEIMRSLSFSTNLQK
130 140 150 160 170 180
190 200
pF1KE3 KLSKQGRPLNDMKQELTTEFRSPR
.: ..
NP_002 RLRRKD
>>NP_067091 (OMIM: 147583) interferon alpha-17 precursor (189 aa)
initn: 364 init1: 349 opt: 360 Z-score: 421.0 bits: 84.7 E(85289): 1e-16
Smith-Waterman score: 360; 38.7% identity (67.7% similar) in 155 aa overlap (35-189:34-188)
10 20 30 40 50 60
pF1KE3 HFFGTVLVLLASTTIFSLDLKLIIFQQRQVNQESLKLLNKLQTLSIQQCLPHRKNFLLPQ
:...: :: .. .: .:: :..: :::
NP_067 SFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFGLPQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 KSLSPQQYQKGHTLAILHEMLQQIFSLFRANISLDGWEENHTEKFLIQLHQQLEYLEALM
. .. .:.:: .....::::.:: :.:: .. : .::.. ::: .:.:::. ::: .
NP_067 EEFDGNQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNNLEACV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GLEAEKLSGTLGSDNLRLQVKMYFRRIHDYLENQDYSTCAWAIVQVEISRCLFFVFSLTE
:. : ... : :. ::.:: :: .. :: ::: .:..:: : : : .: .
NP_067 IQEVGMEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTNLQK
130 140 150 160 170 180
190 200
pF1KE3 KLSKQGRPLNDMKQELTTEFRSPR
: ..
NP_067 ILRRKD
>>NP_002160 (OMIM: 147565) interferon alpha-5 precursor (189 aa)
initn: 330 init1: 314 opt: 357 Z-score: 417.6 bits: 84.1 E(85289): 1.6e-16
Smith-Waterman score: 357; 34.2% identity (64.7% similar) in 190 aa overlap (1-189:1-188)
10 20 30 40 50
pF1KE3 MIIKHFFGTVLVLLASTTIFSLDLKLIIFQQRQV-NQESLKLLNKLQTLSIQQCLPHRKN
: . . .::.: .: :: : : ... :...: .. .. .: .:: :..
NP_002 MALPFVLLMALVVLNCKSICSLGCDLP--QTHSLSNRRTLMIMAQMGRISPFSCLKDRHD
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 FLLPQKSLSPQQYQKGHTLAILHEMLQQIFSLFRANISLDGWEENHTEKFLIQLHQQLEY
: .::. .. .:.::......::::.:: :.:: .. : :.:. .:: .:.:::.
NP_002 FGFPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWDETLLDKFYTELYQQLND
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE3 LEALMGLEAEKLSGTLGSDNLRLQVKMYFRRIHDYLENQDYSTCAWAIVQVEISRCLFFV
::: : :. . : . . : :. ::.:: :: .. :: ::: .:..:: : . .
NP_002 LEACMMQEVGVEDTPLMNVDSILTVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLS
120 130 140 150 160 170
180 190 200
pF1KE3 FSLTEKLSKQGRPLNDMKQELTTEFRSPR
.: :.: ..
NP_002 ANLQERLRRKE
180
>>NP_066546 (OMIM: 147564) interferon alpha-4 precursor (189 aa)
initn: 361 init1: 346 opt: 357 Z-score: 417.6 bits: 84.1 E(85289): 1.6e-16
Smith-Waterman score: 357; 37.4% identity (69.0% similar) in 155 aa overlap (35-189:34-188)
10 20 30 40 50 60
pF1KE3 HFFGTVLVLLASTTIFSLDLKLIIFQQRQVNQESLKLLNKLQTLSIQQCLPHRKNFLLPQ
:...: :: .. .: .:: :..: .:.
NP_066 SFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRHDFGFPE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 KSLSPQQYQKGHTLAILHEMLQQIFSLFRANISLDGWEENHTEKFLIQLHQQLEYLEALM
. .. .:.::......::::.:: :.:: .. : .::.. ::: .:.:::. ::: .
NP_066 EEFDGHQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLEACV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GLEAEKLSGTLGSDNLRLQVKMYFRRIHDYLENQDYSTCAWAIVQVEISRCLFFVFSLTE
:. : ... : :. ::.:: :: .. :: ::: .:..:: : : : .: .
NP_066 IQEVGVEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTNLQK
130 140 150 160 170 180
190 200
pF1KE3 KLSKQGRPLNDMKQELTTEFRSPR
.: ..
NP_066 RLRRKD
208 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 03:21:19 2016 done: Mon Nov 7 03:21:20 2016
Total Scan time: 6.180 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]