Result of FASTA (ccds) for
pFN21AE3040
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3040, 177 aa
1>>>pF1KE3040 177 - 177 aa - 177 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0905+/-0.000736; mu= 13.3182+/- 0.044
mean_var=58.0549+/-11.445, 0's: 0 Z-trim(107.8): 18 B-trim: 0 in 0/50
Lambda= 0.168327
statistics sampled from 9791 (9809) to 9791 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.697), E-opt: 0.2 (0.301), width: 16
Scan time: 1.880
The best scores are: opt bits E(32554)
CCDS11578.1 NME1 gene_id:4830|Hs108|chr17 ( 177) 1204 300.3 4.2e-82
CCDS11579.1 NME1 gene_id:4830|Hs108|chr17 ( 152) 1038 259.9 5e-70
CCDS32682.1 NME2 gene_id:654364|Hs108|chr17 ( 267) 933 234.5 3.9e-62
CCDS11580.1 NME2 gene_id:4831|Hs108|chr17 ( 152) 928 233.2 5.5e-62
CCDS10443.1 NME3 gene_id:4832|Hs108|chr16 ( 169) 726 184.2 3.6e-47
CCDS10408.1 NME4 gene_id:4833|Hs108|chr16 ( 187) 621 158.7 1.8e-39
CCDS66886.1 NME4 gene_id:4833|Hs108|chr16 ( 117) 452 117.5 2.8e-27
CCDS74107.1 NME2 gene_id:4831|Hs108|chr17 ( 82) 439 114.3 1.8e-26
CCDS73797.1 NME4 gene_id:4833|Hs108|chr16 ( 153) 289 78.0 2.9e-15
CCDS44274.1 NME7 gene_id:29922|Hs108|chr1 ( 340) 245 67.5 9.4e-12
CCDS1277.1 NME7 gene_id:29922|Hs108|chr1 ( 376) 245 67.5 1e-11
>>CCDS11578.1 NME1 gene_id:4830|Hs108|chr17 (177 aa)
initn: 1204 init1: 1204 opt: 1204 Z-score: 1587.5 bits: 300.3 E(32554): 4.2e-82
Smith-Waterman score: 1204; 100.0% identity (100.0% similar) in 177 aa overlap (1-177:1-177)
10 20 30 40 50 60
pF1KE3 MVLLSTLGIVFQGEGPPISSCDTGTMANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MVLLSTLGIVFQGEGPPISSCDTGTMANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFRL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VGLKFMQASEDLLKEHYVDLKDRPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 VGLKFMQASEDLLKEHYVDLKDRPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETN
70 80 90 100 110 120
130 140 150 160 170
pF1KE3 PADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIGLWFHPEELVDYTSCAQNWIYE
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 PADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIGLWFHPEELVDYTSCAQNWIYE
130 140 150 160 170
>>CCDS11579.1 NME1 gene_id:4830|Hs108|chr17 (152 aa)
initn: 1038 init1: 1038 opt: 1038 Z-score: 1370.6 bits: 259.9 E(32554): 5e-70
Smith-Waterman score: 1038; 100.0% identity (100.0% similar) in 152 aa overlap (26-177:1-152)
10 20 30 40 50 60
pF1KE3 MVLLSTLGIVFQGEGPPISSCDTGTMANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFRL
:::::::::::::::::::::::::::::::::::
CCDS11 MANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFRL
10 20 30
70 80 90 100 110 120
pF1KE3 VGLKFMQASEDLLKEHYVDLKDRPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 VGLKFMQASEDLLKEHYVDLKDRPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETN
40 50 60 70 80 90
130 140 150 160 170
pF1KE3 PADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIGLWFHPEELVDYTSCAQNWIYE
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 PADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIGLWFHPEELVDYTSCAQNWIYE
100 110 120 130 140 150
>>CCDS32682.1 NME2 gene_id:654364|Hs108|chr17 (267 aa)
initn: 933 init1: 933 opt: 933 Z-score: 1229.1 bits: 234.5 E(32554): 3.9e-62
Smith-Waterman score: 933; 88.2% identity (97.4% similar) in 153 aa overlap (25-177:115-267)
10 20 30 40 50
pF1KE3 MVLLSTLGIVFQGEGPPISSCDTGTMANCERTFIAIKPDGVQRGLVGEIIKRFE
:::: :::::::::::::::::::::::::
CCDS32 KTGRVMLGETNPADSKPGTIRGDFCIQVGRTMANLERTFIAIKPDGVQRGLVGEIIKRFE
90 100 110 120 130 140
60 70 80 90 100 110
pF1KE3 QKGFRLVGLKFMQASEDLLKEHYVDLKDRPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRV
:::::::..::..:::. ::.::.:::::::: ::::::.::::::::::::::::::::
CCDS32 QKGFRLVAMKFLRASEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVAMVWEGLNVVKTGRV
150 160 170 180 190 200
120 130 140 150 160 170
pF1KE3 MLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIGLWFHPEELVDYTSCAQNW
::::::::::::::::::::::::::::::::::.::::::.:::.::::::: :::..:
CCDS32 MLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVKSAEKEISLWFKPEELVDYKSCAHDW
210 220 230 240 250 260
pF1KE3 IYE
.::
CCDS32 VYE
>--
initn: 771 init1: 771 opt: 771 Z-score: 1016.4 bits: 195.2 E(32554): 2.7e-50
Smith-Waterman score: 771; 100.0% identity (100.0% similar) in 114 aa overlap (26-139:1-114)
10 20 30 40 50 60
pF1KE3 MVLLSTLGIVFQGEGPPISSCDTGTMANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFRL
:::::::::::::::::::::::::::::::::::
CCDS32 MANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFRL
10 20 30
70 80 90 100 110 120
pF1KE3 VGLKFMQASEDLLKEHYVDLKDRPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 VGLKFMQASEDLLKEHYVDLKDRPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETN
40 50 60 70 80 90
130 140 150 160 170
pF1KE3 PADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIGLWFHPEELVDYTSCAQNWIYE
:::::::::::::::::::
CCDS32 PADSKPGTIRGDFCIQVGRTMANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKF
100 110 120 130 140 150
>>CCDS11580.1 NME2 gene_id:4831|Hs108|chr17 (152 aa)
initn: 928 init1: 928 opt: 928 Z-score: 1226.3 bits: 233.2 E(32554): 5.5e-62
Smith-Waterman score: 928; 88.2% identity (97.4% similar) in 152 aa overlap (26-177:1-152)
10 20 30 40 50 60
pF1KE3 MVLLSTLGIVFQGEGPPISSCDTGTMANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFRL
::: :::::::::::::::::::::::::::::::
CCDS11 MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRL
10 20 30
70 80 90 100 110 120
pF1KE3 VGLKFMQASEDLLKEHYVDLKDRPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETN
:..::..:::. ::.::.:::::::: ::::::.::::::::::::::::::::::::::
CCDS11 VAMKFLRASEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETN
40 50 60 70 80 90
130 140 150 160 170
pF1KE3 PADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIGLWFHPEELVDYTSCAQNWIYE
::::::::::::::::::::::::::::.::::::.:::.::::::: :::..:.::
CCDS11 PADSKPGTIRGDFCIQVGRNIIHGSDSVKSAEKEISLWFKPEELVDYKSCAHDWVYE
100 110 120 130 140 150
>>CCDS10443.1 NME3 gene_id:4832|Hs108|chr16 (169 aa)
initn: 726 init1: 726 opt: 726 Z-score: 960.4 bits: 184.2 E(32554): 3.6e-47
Smith-Waterman score: 726; 67.6% identity (93.2% similar) in 148 aa overlap (30-177:22-169)
10 20 30 40 50 60
pF1KE3 MVLLSTLGIVFQGEGPPISSCDTGTMANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFRL
::::.:.::::::: :::::..:::.:::.:
CCDS10 MICLVLTIFANLFPAACTGAHERTFLAVKPDGVQRRLVGEIVRRFERKGFKL
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 VGLKFMQASEDLLKEHYVDLKDRPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETN
:.::..::::.::.:::..:..:::.. ::::: :::::::::.::.::.:.:...: ::
CCDS10 VALKLVQASEELLREHYAELRERPFYGRLVKYMASGPVVAMVWQGLDVVRTSRALIGATN
60 70 80 90 100 110
130 140 150 160 170
pF1KE3 PADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIGLWFHPEELVDYTSCAQNWIYE
:::. ::::::::::.::.:.::::::::::..::.:::. .::. . . : .:.::
CCDS10 PADAPPGTIRGDFCIEVGKNLIHGSDSVESARREIALWFRADELLCWEDSAGHWLYE
120 130 140 150 160
>>CCDS10408.1 NME4 gene_id:4833|Hs108|chr16 (187 aa)
initn: 636 init1: 621 opt: 621 Z-score: 822.0 bits: 158.7 E(32554): 1.8e-39
Smith-Waterman score: 621; 58.3% identity (88.9% similar) in 144 aa overlap (30-173:38-181)
10 20 30 40 50
pF1KE3 MVLLSTLGIVFQGEGPPISSCDTGTMANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFR
:::..:.::::::: :::..:.:::..::
CCDS10 SALRGLRCGPRAPGPSLLVRHGSGGPSWTRERTLVAVKPDGVQRRLVGDVIQRFERRGFT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 LVGLKFMQASEDLLKEHYVDLKDRPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGET
:::.:..:: :..: ::: ::. .::. .:..:: ::::::::::: :::...:.:.:.:
CCDS10 LVGMKMLQAPESVLAEHYQDLRRKPFYPALIRYMSSGPVVAMVWEGYNVVRASRAMIGHT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 NPADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIGLWFHPEELVDYTSCAQNWIYE
. :.. :::::::: ....::.::.:::::.:..:: :::. :::.... .:.
CCDS10 DSAEAAPGTIRGDFSVHISRNVIHASDSVEGAQREIQLWFQSSELVSWADGGQHSSIHPA
130 140 150 160 170 180
>>CCDS66886.1 NME4 gene_id:4833|Hs108|chr16 (117 aa)
initn: 440 init1: 440 opt: 452 Z-score: 603.3 bits: 117.5 E(32554): 2.8e-27
Smith-Waterman score: 452; 55.0% identity (87.4% similar) in 111 aa overlap (63-173:1-111)
40 50 60 70 80 90
pF1KE3 FIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFMQASEDLLKEHYVDLKDRPFFAGLVKY
.:..:: :..: ::: ::. .::. .:..:
CCDS66 MKMLQAPESVLAEHYQDLRRKPFYPALIRY
10 20 30
100 110 120 130 140 150
pF1KE3 MHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGRNIIHGSDSVESAE
: ::::::::::: :::...:.:.:.:. :.. :::::::: ....::.::.:::::.:.
CCDS66 MSSGPVVAMVWEGYNVVRASRAMIGHTDSAEAAPGTIRGDFSVHISRNVIHASDSVEGAQ
40 50 60 70 80 90
160 170
pF1KE3 KEIGLWFHPEELVDYTSCAQNWIYE
.:: :::. :::.... .:.
CCDS66 REIQLWFQSSELVSWADGGQHSSIHPA
100 110
>>CCDS74107.1 NME2 gene_id:4831|Hs108|chr17 (82 aa)
initn: 439 init1: 439 opt: 439 Z-score: 588.6 bits: 114.3 E(32554): 1.8e-26
Smith-Waterman score: 439; 85.5% identity (96.1% similar) in 76 aa overlap (26-101:1-76)
10 20 30 40 50 60
pF1KE3 MVLLSTLGIVFQGEGPPISSCDTGTMANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFRL
::: :::::::::::::::::::::::::::::::
CCDS74 MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRL
10 20 30
70 80 90 100 110 120
pF1KE3 VGLKFMQASEDLLKEHYVDLKDRPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETN
:..::..:::. ::.::.:::::::: ::::::.:::::::
CCDS74 VAMKFLRASEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVAMEHHSWQ
40 50 60 70 80
130 140 150 160 170
pF1KE3 PADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIGLWFHPEELVDYTSCAQNWIYE
>>CCDS73797.1 NME4 gene_id:4833|Hs108|chr16 (153 aa)
initn: 464 init1: 288 opt: 289 Z-score: 387.6 bits: 78.0 E(32554): 2.9e-15
Smith-Waterman score: 398; 44.4% identity (69.4% similar) in 144 aa overlap (30-173:38-147)
10 20 30 40 50
pF1KE3 MVLLSTLGIVFQGEGPPISSCDTGTMANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFR
:::..:.::::::: :::..:.:::..::
CCDS73 SALRGLRCGPRAPGPSLLVRHGSGGPSWTRERTLVAVKPDGVQRRLVGDVIQRFERRGFT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 LVGLKFMQASEDLLKEHYVDLKDRPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGET
:::.:..: :::: :::...:.:.:.:
CCDS73 LVGMKMLQ----------------------------------VWEGYNVVRASRAMIGHT
70 80 90
120 130 140 150 160 170
pF1KE3 NPADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIGLWFHPEELVDYTSCAQNWIYE
. :.. :::::::: ....::.::.:::::.:..:: :::. :::.... .:.
CCDS73 DSAEAAPGTIRGDFSVHISRNVIHASDSVEGAQREIQLWFQSSELVSWADGGQHSSIHPA
100 110 120 130 140 150
>>CCDS44274.1 NME7 gene_id:29922|Hs108|chr1 (340 aa)
initn: 231 init1: 148 opt: 245 Z-score: 324.5 bits: 67.5 E(32554): 9.4e-12
Smith-Waterman score: 251; 31.3% identity (62.0% similar) in 150 aa overlap (30-170:56-203)
10 20 30 40 50
pF1KE3 MVLLSTLGIVFQGEGPPISSCDTGTMANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFR
:.:. ::::..... ::::. ... ::
CCDS44 IGNKVNVFSRQLVLIDYGDQYTARQLGSRKEKTLALIKPDAISKA--GEIIEIINKAGFT
30 40 50 60 70 80
60 70 80 90 100 110
pF1KE3 LVGLKFMQASEDLLKEHYVDLKDRPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGET
.. ::.:. :. . .:: ..:::: :.... .::..:: ... . .:: .
CCDS44 ITKLKMMMLSRKEALDFHVDHQSRPFFNELIQFITTGPIIAMEILRDDAICEWKRLLGPA
90 100 110 120 130 140
120 130 140 150 160 170
pF1KE3 NPADSKPG---TIRGDFCIQVGRNIIHGSDSVESAEKEIGLWFH------PEELVDYTSC
: . .. .::. : . :: :: :: :: .:. :.: : . . .:.:
CCDS44 NSGVARTDASESIRALFGTDGIRNAAHGPDSFASAAREMELFFPSSGGCGPANTAKFTNC
150 160 170 180 190 200
pF1KE3 AQNWIYE
CCDS44 TCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEYHDMV
210 220 230 240 250 260
177 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 19:23:35 2016 done: Thu Nov 3 19:23:35 2016
Total Scan time: 1.880 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]