Result of FASTA (ccds) for
pFN21AE3035
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3035, 168 aa
1>>>pF1KE3035 168 - 168 aa - 168 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9954+/-0.000647; mu= 14.3050+/- 0.039
mean_var=64.6551+/-12.815, 0's: 0 Z-trim(110.9): 23 B-trim: 114 in 1/49
Lambda= 0.159504
statistics sampled from 11970 (11987) to 11970 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.761), E-opt: 0.2 (0.368), width: 16
Scan time: 1.520
The best scores are: opt bits E(32554)
CCDS31070.1 GREM2 gene_id:64388|Hs108|chr1 ( 168) 1150 272.5 8.5e-74
CCDS10029.1 GREM1 gene_id:26585|Hs108|chr15 ( 184) 622 151.0 3.4e-37
CCDS53927.1 GREM1 gene_id:26585|Hs108|chr15 ( 143) 577 140.6 3.7e-34
CCDS196.2 NBL1 gene_id:4681|Hs108|chr1 ( 181) 249 65.2 2.3e-11
CCDS72720.1 NBL1 gene_id:4681|Hs108|chr1 ( 215) 249 65.2 2.7e-11
CCDS41278.1 NBL1 gene_id:4681|Hs108|chr1 ( 216) 249 65.2 2.7e-11
>>CCDS31070.1 GREM2 gene_id:64388|Hs108|chr1 (168 aa)
initn: 1150 init1: 1150 opt: 1150 Z-score: 1438.4 bits: 272.5 E(32554): 8.5e-74
Smith-Waterman score: 1150; 100.0% identity (100.0% similar) in 168 aa overlap (1-168:1-168)
10 20 30 40 50 60
pF1KE3 MFWKLSLSLFLVAVLVKVAEARKNRPAGAIPSPYKDGSSNNSERWQHQIKEVLASSQEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 MFWKLSLSLFLVAVLVKVAEARKNRPAGAIPSPYKDGSSNNSERWQHQIKEVLASSQEAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VVTERKYLKSDWCKTQPLRQTVSEEGCRSRTILNRFCYGQCNSFYIPRHVKKEEESFQSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 VVTERKYLKSDWCKTQPLRQTVSEEGCRSRTILNRFCYGQCNSFYIPRHVKKEEESFQSC
70 80 90 100 110 120
130 140 150 160
pF1KE3 AFCKPQRVTSVLVELECPGLDPPFRLKKIQKVKQCRCMSVNLSDSDKQ
::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 AFCKPQRVTSVLVELECPGLDPPFRLKKIQKVKQCRCMSVNLSDSDKQ
130 140 150 160
>>CCDS10029.1 GREM1 gene_id:26585|Hs108|chr15 (184 aa)
initn: 675 init1: 614 opt: 622 Z-score: 781.2 bits: 151.0 E(32554): 3.4e-37
Smith-Waterman score: 647; 55.5% identity (75.1% similar) in 173 aa overlap (9-162:12-183)
10 20 30 40 50
pF1KE3 MFWKLSLSLFLVAVLVKVAEARKNRPAGAIPSPYKDGSSNNSERWQHQIK-------
:.:...:. .::..:. :::: : : .. :.::. : .
CCDS10 MSRTAYTVGALLLLLGTLLPAAEGKKKGSQGAIPPPDK-AQHNDSEQTQSPQQPGSRNRG
10 20 30 40 50
60 70 80 90
pF1KE3 ------------EVLASSQEALVVTERKYLKSDWCKTQPLRQTVSEEGCRSRTILNRFCY
::: :::::: :::::::: ::::::::.::. :::: ::::.:::::
CCDS10 RGQGRGTAMPGEEVLESSQEALHVTERKYLKRDWCKTQPLKQTIHEEGCNSRTIINRFCY
60 70 80 90 100 110
100 110 120 130 140 150
pF1KE3 GQCNSFYIPRHVKKEEESFQSCAFCKPQRVTSVLVELECPGLDPPFRLKKIQKVKQCRCM
:::::::::::..::: :::::.::::.. :...: :.:: :.:: . :.. .::::::.
CCDS10 GQCNSFYIPRHIRKEEGSFQSCSFCKPKKFTTMMVTLNCPELQPPTKKKRVTRVKQCRCI
120 130 140 150 160 170
160
pF1KE3 SVNLSDSDKQ
:..:
CCDS10 SIDLD
180
>>CCDS53927.1 GREM1 gene_id:26585|Hs108|chr15 (143 aa)
initn: 617 init1: 576 opt: 577 Z-score: 726.8 bits: 140.6 E(32554): 3.7e-34
Smith-Waterman score: 592; 55.2% identity (74.0% similar) in 154 aa overlap (9-162:12-142)
10 20 30 40 50
pF1KE3 MFWKLSLSLFLVAVLVKVAEARKNRPAGAIPSPYKDGSSNNSERWQHQIKEVLASSQ
:.:...:. .::..:. :::: : :
CCDS53 MSRTAYTVGALLLLLGTLLPAAEGKKKGSQGAIPPPDK----------------------
10 20 30
60 70 80 90 100 110
pF1KE3 EALVVTERKYLKSDWCKTQPLRQTVSEEGCRSRTILNRFCYGQCNSFYIPRHVKKEEESF
:: :::::::: ::::::::.::. :::: ::::.::::::::::::::::..::: ::
CCDS53 -ALHVTERKYLKRDWCKTQPLKQTIHEEGCNSRTIINRFCYGQCNSFYIPRHIRKEEGSF
40 50 60 70 80 90
120 130 140 150 160
pF1KE3 QSCAFCKPQRVTSVLVELECPGLDPPFRLKKIQKVKQCRCMSVNLSDSDKQ
:::.::::.. :...: :.:: :.:: . :.. .::::::.:..:
CCDS53 QSCSFCKPKKFTTMMVTLNCPELQPPTKKKRVTRVKQCRCISIDLD
100 110 120 130 140
>>CCDS196.2 NBL1 gene_id:4681|Hs108|chr1 (181 aa)
initn: 231 init1: 217 opt: 249 Z-score: 317.4 bits: 65.2 E(32554): 2.3e-11
Smith-Waterman score: 249; 35.9% identity (62.0% similar) in 92 aa overlap (69-159:31-122)
40 50 60 70 80 90
pF1KE3 SNNSERWQHQIKEVLASSQEALVVTERKYLKSDWCKTQPLRQTVSEEGCRSRTILNRFCY
:: ::... . : :.. ::....: :: :
CCDS19 MMLRVLVGAVLPAMLLAAPPPINKLALFPDKSAWCEAKNITQIVGHSGCEAKSIQNRACL
10 20 30 40 50 60
100 110 120 130 140 150
pF1KE3 GQCNSFYIPRHVKKEEESFQSCAFCKPQRVTSVLVELECPGLDPPFRLKK-IQKVKQCRC
::: :. .: . ::. : : : . .: ::::: . :. : ..:. .: :
CCDS19 GQCFSYSVPNTFPQSTESLVHCDSCMPAQSMWEIVTLECPGHEEVPRVDKLVEKILHCSC
70 80 90 100 110 120
160
pF1KE3 MSVNLSDSDKQ
..
CCDS19 QACGKEPSHEGLSVYVQGEDGPGSQPGTHPHPHPHPHPGGQTPEPEDPPGAPHTEEEGAE
130 140 150 160 170 180
>>CCDS72720.1 NBL1 gene_id:4681|Hs108|chr1 (215 aa)
initn: 248 init1: 217 opt: 249 Z-score: 316.3 bits: 65.2 E(32554): 2.7e-11
Smith-Waterman score: 249; 35.9% identity (62.0% similar) in 92 aa overlap (69-159:65-156)
40 50 60 70 80 90
pF1KE3 SNNSERWQHQIKEVLASSQEALVVTERKYLKSDWCKTQPLRQTVSEEGCRSRTILNRFCY
:: ::... . : :.. ::....: :: :
CCDS72 MMLRVLVGAVLPAMLLAAPPPINKLALFPDKSAWCEAKNITQIVGHSGCEAKSIQNRACL
40 50 60 70 80 90
100 110 120 130 140 150
pF1KE3 GQCNSFYIPRHVKKEEESFQSCAFCKPQRVTSVLVELECPGLDPPFRLKK-IQKVKQCRC
::: :. .: . ::. : : : . .: ::::: . :. : ..:. .: :
CCDS72 GQCFSYSVPNTFPQSTESLVHCDSCMPAQSMWEIVTLECPGHEEVPRVDKLVEKILHCSC
100 110 120 130 140 150
160
pF1KE3 MSVNLSDSDKQ
..
CCDS72 QACGKEPSHEGLSVYVQGEDGPGSQPGTHPHPHPHPHPGGQTPEPEDPPGAPHTEEEGAE
160 170 180 190 200 210
>>CCDS41278.1 NBL1 gene_id:4681|Hs108|chr1 (216 aa)
initn: 231 init1: 217 opt: 249 Z-score: 316.3 bits: 65.2 E(32554): 2.7e-11
Smith-Waterman score: 249; 35.9% identity (62.0% similar) in 92 aa overlap (69-159:66-157)
40 50 60 70 80 90
pF1KE3 SNNSERWQHQIKEVLASSQEALVVTERKYLKSDWCKTQPLRQTVSEEGCRSRTILNRFCY
:: ::... . : :.. ::....: :: :
CCDS41 MMLRVLVGAVLPAMLLAAPPPINKLALFPDKSAWCEAKNITQIVGHSGCEAKSIQNRACL
40 50 60 70 80 90
100 110 120 130 140 150
pF1KE3 GQCNSFYIPRHVKKEEESFQSCAFCKPQRVTSVLVELECPGLDPPFRLKK-IQKVKQCRC
::: :. .: . ::. : : : . .: ::::: . :. : ..:. .: :
CCDS41 GQCFSYSVPNTFPQSTESLVHCDSCMPAQSMWEIVTLECPGHEEVPRVDKLVEKILHCSC
100 110 120 130 140 150
160
pF1KE3 MSVNLSDSDKQ
..
CCDS41 QACGKEPSHEGLSVYVQGEDGPGSQPGTHPHPHPHPHPGGQTPEPEDPPGAPHTEEEGAE
160 170 180 190 200 210
168 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 12:38:47 2016 done: Sun Nov 6 12:38:48 2016
Total Scan time: 1.520 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]