Result of FASTA (omim) for
pFN21AE3031
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3031, 156 aa
1>>>pF1KE3031 156 - 156 aa - 156 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.6632+/-0.00043; mu= 14.3860+/- 0.026
mean_var=54.4024+/-10.868, 0's: 0 Z-trim(109.6): 48 B-trim: 33 in 1/48
Lambda= 0.173886
statistics sampled from 17766 (17806) to 17766 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.566), E-opt: 0.2 (0.209), width: 16
Scan time: 4.950
The best scores are: opt bits E(85289)
NP_612469 (OMIM: 607888) CKLF-like MARVEL transmem ( 156) 998 258.5 3.1e-69
XP_016876442 (OMIM: 607888) PREDICTED: CKLF-like M ( 156) 998 258.5 3.1e-69
XP_016876443 (OMIM: 607888) PREDICTED: CKLF-like M ( 156) 998 258.5 3.1e-69
NP_001032365 (OMIM: 607888) CKLF-like MARVEL trans ( 125) 607 160.4 8.9e-40
NP_001275675 (OMIM: 607888) CKLF-like MARVEL trans ( 223) 603 159.5 2.8e-39
NP_001275673 (OMIM: 607888) CKLF-like MARVEL trans ( 105) 400 108.4 3.3e-24
NP_853531 (OMIM: 607886) CKLF-like MARVEL transmem ( 182) 336 92.5 3.5e-19
XP_006721194 (OMIM: 607886) PREDICTED: CKLF-like M ( 182) 336 92.5 3.5e-19
NP_653202 (OMIM: 607886) CKLF-like MARVEL transmem ( 182) 336 92.5 3.5e-19
NP_001275674 (OMIM: 607888) CKLF-like MARVEL trans ( 74) 278 77.7 4.1e-15
NP_002659 (OMIM: 300112) proteolipid protein 2 [Ho ( 152) 255 72.1 4e-13
XP_011521163 (OMIM: 607886) PREDICTED: CKLF-like M ( 150) 188 55.3 4.5e-08
XP_011521184 (OMIM: 607887) PREDICTED: CKLF-like M ( 179) 144 44.3 0.00011
NP_852662 (OMIM: 607887) CKLF-like MARVEL transmem ( 208) 144 44.4 0.00012
XP_016878443 (OMIM: 607887) PREDICTED: CKLF-like M ( 221) 144 44.4 0.00013
NP_848933 (OMIM: 607887) CKLF-like MARVEL transmem ( 234) 144 44.4 0.00014
NP_612419 (OMIM: 607890) CKLF-like MARVEL transmem ( 175) 141 43.6 0.00018
XP_011531621 (OMIM: 607890) PREDICTED: CKLF-like M ( 151) 130 40.8 0.0011
NP_849199 (OMIM: 607891) CKLF-like MARVEL transmem ( 173) 130 40.8 0.0012
XP_016861135 (OMIM: 607890) PREDICTED: CKLF-like M ( 179) 130 40.8 0.0012
NP_057077 (OMIM: 600340) plasmolipin [Homo sapiens ( 182) 127 40.0 0.0021
NP_058647 (OMIM: 616074) chemokine-like factor iso ( 152) 122 38.7 0.0044
NP_443725 (OMIM: 607884) CKLF-like MARVEL transmem ( 286) 123 39.2 0.0062
NP_851785 (OMIM: 607884) CKLF-like MARVEL transmem ( 231) 121 38.6 0.0073
>>NP_612469 (OMIM: 607888) CKLF-like MARVEL transmembran (156 aa)
initn: 998 init1: 998 opt: 998 Z-score: 1363.9 bits: 258.5 E(85289): 3.1e-69
Smith-Waterman score: 998; 100.0% identity (100.0% similar) in 156 aa overlap (1-156:1-156)
10 20 30 40 50 60
pF1KE3 MLSARDRRDRHPEEGVVAELQGFAVDKAFLTSHKGILLETELALTLIIFICFTASISAYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 MLSARDRRDRHPEEGVVAELQGFAVDKAFLTSHKGILLETELALTLIIFICFTASISAYM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 AAALLEFFITLAFLFLYATQYYQRFDRINWPCLDFLRCVSAIIIFLVVSFAAVTSRDGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 AAALLEFFITLAFLFLYATQYYQRFDRINWPCLDFLRCVSAIIIFLVVSFAAVTSRDGAA
70 80 90 100 110 120
130 140 150
pF1KE3 IAAFVFGIILVSIFAYDAFKIYRTEMAPGASQGDQQ
::::::::::::::::::::::::::::::::::::
NP_612 IAAFVFGIILVSIFAYDAFKIYRTEMAPGASQGDQQ
130 140 150
>>XP_016876442 (OMIM: 607888) PREDICTED: CKLF-like MARVE (156 aa)
initn: 998 init1: 998 opt: 998 Z-score: 1363.9 bits: 258.5 E(85289): 3.1e-69
Smith-Waterman score: 998; 100.0% identity (100.0% similar) in 156 aa overlap (1-156:1-156)
10 20 30 40 50 60
pF1KE3 MLSARDRRDRHPEEGVVAELQGFAVDKAFLTSHKGILLETELALTLIIFICFTASISAYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLSARDRRDRHPEEGVVAELQGFAVDKAFLTSHKGILLETELALTLIIFICFTASISAYM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 AAALLEFFITLAFLFLYATQYYQRFDRINWPCLDFLRCVSAIIIFLVVSFAAVTSRDGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAALLEFFITLAFLFLYATQYYQRFDRINWPCLDFLRCVSAIIIFLVVSFAAVTSRDGAA
70 80 90 100 110 120
130 140 150
pF1KE3 IAAFVFGIILVSIFAYDAFKIYRTEMAPGASQGDQQ
::::::::::::::::::::::::::::::::::::
XP_016 IAAFVFGIILVSIFAYDAFKIYRTEMAPGASQGDQQ
130 140 150
>>XP_016876443 (OMIM: 607888) PREDICTED: CKLF-like MARVE (156 aa)
initn: 998 init1: 998 opt: 998 Z-score: 1363.9 bits: 258.5 E(85289): 3.1e-69
Smith-Waterman score: 998; 100.0% identity (100.0% similar) in 156 aa overlap (1-156:1-156)
10 20 30 40 50 60
pF1KE3 MLSARDRRDRHPEEGVVAELQGFAVDKAFLTSHKGILLETELALTLIIFICFTASISAYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLSARDRRDRHPEEGVVAELQGFAVDKAFLTSHKGILLETELALTLIIFICFTASISAYM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 AAALLEFFITLAFLFLYATQYYQRFDRINWPCLDFLRCVSAIIIFLVVSFAAVTSRDGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAALLEFFITLAFLFLYATQYYQRFDRINWPCLDFLRCVSAIIIFLVVSFAAVTSRDGAA
70 80 90 100 110 120
130 140 150
pF1KE3 IAAFVFGIILVSIFAYDAFKIYRTEMAPGASQGDQQ
::::::::::::::::::::::::::::::::::::
XP_016 IAAFVFGIILVSIFAYDAFKIYRTEMAPGASQGDQQ
130 140 150
>>NP_001032365 (OMIM: 607888) CKLF-like MARVEL transmemb (125 aa)
initn: 607 init1: 607 opt: 607 Z-score: 835.1 bits: 160.4 E(85289): 8.9e-40
Smith-Waterman score: 738; 80.1% identity (80.1% similar) in 156 aa overlap (1-156:1-125)
10 20 30 40 50 60
pF1KE3 MLSARDRRDRHPEEGVVAELQGFAVDKAFLTSHKGILLETELALTLIIFICFTASISAYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLSARDRRDRHPEEGVVAELQGFAVDKAFLTSHKGILLETELALTLIIFICFTASISAYM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 AAALLEFFITLAFLFLYATQYYQRFDRINWPCLDFLRCVSAIIIFLVVSFAAVTSRDGAA
:::::::::::::::::::::::::::::::::
NP_001 AAALLEFFITLAFLFLYATQYYQRFDRINWPCL---------------------------
70 80 90
130 140 150
pF1KE3 IAAFVFGIILVSIFAYDAFKIYRTEMAPGASQGDQQ
::::::::::::::::::::::::::::::::
NP_001 ----VFGIILVSIFAYDAFKIYRTEMAPGASQGDQQ
100 110 120
>>NP_001275675 (OMIM: 607888) CKLF-like MARVEL transmemb (223 aa)
initn: 984 init1: 603 opt: 603 Z-score: 826.1 bits: 159.5 E(85289): 2.8e-39
Smith-Waterman score: 629; 64.4% identity (64.4% similar) in 188 aa overlap (1-121:1-188)
10 20 30 40 50 60
pF1KE3 MLSARDRRDRHPEEGVVAELQGFAVDKAFLTSHKGILLETELALTLIIFICFTASISAYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLSARDRRDRHPEEGVVAELQGFAVDKAFLTSHKGILLETELALTLIIFICFTASISAYM
10 20 30 40 50 60
70 80 90
pF1KE3 AAALLEFFITLAFLFLYATQYYQRFDRINWPCL---------------------------
:::::::::::::::::::::::::::::::::
NP_001 AAALLEFFITLAFLFLYATQYYQRFDRINWPCLLQGHGQSGGPHPLDLLSHSAKVQPQPW
70 80 90 100 110 120
100 110
pF1KE3 ----------------------------------------DFLRCVSAIIIFLVVSFAAV
::::::::::::::::::::
NP_001 PGLTPPGWHTPAAVPWVPAPAPGFWSWLLWFICFHSLGSSDFLRCVSAIIIFLVVSFAAV
130 140 150 160 170 180
120 130 140 150
pF1KE3 TSRDGAAIAAFVFGIILVSIFAYDAFKIYRTEMAPGASQGDQQ
::::::::
NP_001 TSRDGAAIAAFVFGIILVSIFAYDAFKIYRTEMAPGASQGDQQ
190 200 210 220
>--
initn: 225 init1: 225 opt: 225 Z-score: 313.6 bits: 64.7 E(85289): 1e-10
Smith-Waterman score: 225; 100.0% identity (100.0% similar) in 35 aa overlap (122-156:189-223)
100 110 120 130 140 150
pF1KE3 CLDFLRCVSAIIIFLVVSFAAVTSRDGAAIAAFVFGIILVSIFAYDAFKIYRTEMAPGAS
::::::::::::::::::::::::::::::
NP_001 SSDFLRCVSAIIIFLVVSFAAVTSRDGAAIAAFVFGIILVSIFAYDAFKIYRTEMAPGAS
160 170 180 190 200 210
pF1KE3 QGDQQ
:::::
NP_001 QGDQQ
220
>>NP_001275673 (OMIM: 607888) CKLF-like MARVEL transmemb (105 aa)
initn: 400 init1: 400 opt: 400 Z-score: 555.6 bits: 108.4 E(85289): 3.3e-24
Smith-Waterman score: 551; 67.3% identity (67.3% similar) in 156 aa overlap (1-156:1-105)
10 20 30 40 50 60
pF1KE3 MLSARDRRDRHPEEGVVAELQGFAVDKAFLTSHKGILLETELALTLIIFICFTASISAYM
::::::::::::::::::::::::::::::::::::::::::
NP_001 MLSARDRRDRHPEEGVVAELQGFAVDKAFLTSHKGILLETEL------------------
10 20 30 40
70 80 90 100 110 120
pF1KE3 AAALLEFFITLAFLFLYATQYYQRFDRINWPCLDFLRCVSAIIIFLVVSFAAVTSRDGAA
:::::::::::::::::::::::::::
NP_001 ---------------------------------DFLRCVSAIIIFLVVSFAAVTSRDGAA
50 60
130 140 150
pF1KE3 IAAFVFGIILVSIFAYDAFKIYRTEMAPGASQGDQQ
::::::::::::::::::::::::::::::::::::
NP_001 IAAFVFGIILVSIFAYDAFKIYRTEMAPGASQGDQQ
70 80 90 100
>>NP_853531 (OMIM: 607886) CKLF-like MARVEL transmembran (182 aa)
initn: 204 init1: 204 opt: 336 Z-score: 465.4 bits: 92.5 E(85289): 3.5e-19
Smith-Waterman score: 336; 42.1% identity (73.6% similar) in 140 aa overlap (17-154:24-162)
10 20 30 40 50
pF1KE3 MLSARDRRDRHPEEGVVAELQGFAVDKAFLTSHKGILLETELALTLIIFICFT
: :... .::: : :: :: .: .:..: :::..
NP_853 MWPPDPDPDPDPEPAGGSRPGPAVPGLRALLPARAFLCSLKGRLLLAESGLSFITFICYV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 AS-ISAYMAAALLEFFITLAFLFLYATQYYQRFDRINWPCLDFLRCVSAIIIFLVVSFAA
:: ::...: ::::...: ::: : : .... . :: .::::::.: .:....:..:
NP_853 ASSASAFLTAPLLEFLLALYFLFADAMQLNDKWQGLCWPMMDFLRCVTAALIYFAISITA
70 80 90 100 110 120
120 130 140 150
pF1KE3 VTSR-DGAAIAAFVFGIILVSIFAYDAFKIYRTEMAPGASQGDQQ
... :::. :: :::.. . .:: : . :. ...: .:::
NP_853 IAKYSDGASKAAGVFGFFATIVFATDFYLIF-NDVAKFLKQGDSADETTAHKTEEENSDS
130 140 150 160 170
NP_853 DSD
180
>>XP_006721194 (OMIM: 607886) PREDICTED: CKLF-like MARVE (182 aa)
initn: 204 init1: 204 opt: 336 Z-score: 465.4 bits: 92.5 E(85289): 3.5e-19
Smith-Waterman score: 336; 42.1% identity (73.6% similar) in 140 aa overlap (17-154:24-162)
10 20 30 40 50
pF1KE3 MLSARDRRDRHPEEGVVAELQGFAVDKAFLTSHKGILLETELALTLIIFICFT
: :... .::: : :: :: .: .:..: :::..
XP_006 MWPPDPDPDPDPEPAGGSRPGPAVPGLRALLPARAFLCSLKGRLLLAESGLSFITFICYV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 AS-ISAYMAAALLEFFITLAFLFLYATQYYQRFDRINWPCLDFLRCVSAIIIFLVVSFAA
:: ::...: ::::...: ::: : : .... . :: .::::::.: .:....:..:
XP_006 ASSASAFLTAPLLEFLLALYFLFADAMQLNDKWQGLCWPMMDFLRCVTAALIYFAISITA
70 80 90 100 110 120
120 130 140 150
pF1KE3 VTSR-DGAAIAAFVFGIILVSIFAYDAFKIYRTEMAPGASQGDQQ
... :::. :: :::.. . .:: : . :. ...: .:::
XP_006 IAKYSDGASKAAGVFGFFATIVFATDFYLIF-NDVAKFLKQGDSADETTAHKTEEENSDS
130 140 150 160 170
XP_006 DSD
180
>>NP_653202 (OMIM: 607886) CKLF-like MARVEL transmembran (182 aa)
initn: 204 init1: 204 opt: 336 Z-score: 465.4 bits: 92.5 E(85289): 3.5e-19
Smith-Waterman score: 336; 42.1% identity (73.6% similar) in 140 aa overlap (17-154:24-162)
10 20 30 40 50
pF1KE3 MLSARDRRDRHPEEGVVAELQGFAVDKAFLTSHKGILLETELALTLIIFICFT
: :... .::: : :: :: .: .:..: :::..
NP_653 MWPPDPDPDPDPEPAGGSRPGPAVPGLRALLPARAFLCSLKGRLLLAESGLSFITFICYV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 AS-ISAYMAAALLEFFITLAFLFLYATQYYQRFDRINWPCLDFLRCVSAIIIFLVVSFAA
:: ::...: ::::...: ::: : : .... . :: .::::::.: .:....:..:
NP_653 ASSASAFLTAPLLEFLLALYFLFADAMQLNDKWQGLCWPMMDFLRCVTAALIYFAISITA
70 80 90 100 110 120
120 130 140 150
pF1KE3 VTSR-DGAAIAAFVFGIILVSIFAYDAFKIYRTEMAPGASQGDQQ
... :::. :: :::.. . .:: : . :. ...: .:::
NP_653 IAKYSDGASKAAGVFGFFATIVFATDFYLIF-NDVAKFLKQGDSADETTAHKTEEENSDS
130 140 150 160 170
NP_653 DSD
180
>>NP_001275674 (OMIM: 607888) CKLF-like MARVEL transmemb (74 aa)
initn: 284 init1: 276 opt: 278 Z-score: 392.4 bits: 77.7 E(85289): 4.1e-15
Smith-Waterman score: 301; 47.4% identity (47.4% similar) in 156 aa overlap (1-156:1-74)
10 20 30 40 50 60
pF1KE3 MLSARDRRDRHPEEGVVAELQGFAVDKAFLTSHKGILLETELALTLIIFICFTASISAYM
::::::::::::::::::::::::::::::::::::::::::
NP_001 MLSARDRRDRHPEEGVVAELQGFAVDKAFLTSHKGILLETEL------------------
10 20 30 40
70 80 90 100 110 120
pF1KE3 AAALLEFFITLAFLFLYATQYYQRFDRINWPCLDFLRCVSAIIIFLVVSFAAVTSRDGAA
NP_001 ------------------------------------------------------------
130 140 150
pF1KE3 IAAFVFGIILVSIFAYDAFKIYRTEMAPGASQGDQQ
::::::::::::::::::::::::::::::::
NP_001 ----VFGIILVSIFAYDAFKIYRTEMAPGASQGDQQ
50 60 70
156 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 14:29:52 2016 done: Sun Nov 6 14:29:53 2016
Total Scan time: 4.950 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]