Result of FASTA (omim) for
pFN21AE3028
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3028, 151 aa
1>>>pF1KE3028 151 - 151 aa - 151 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.5377+/-0.000376; mu= 16.3179+/- 0.023
mean_var=65.3156+/-13.272, 0's: 0 Z-trim(112.7): 12 B-trim: 0 in 0/49
Lambda= 0.158696
statistics sampled from 21652 (21661) to 21652 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.634), E-opt: 0.2 (0.254), width: 16
Scan time: 4.420
The best scores are: opt bits E(85289)
NP_001225 (OMIM: 123320,192600,601253,606072,60780 ( 151) 1037 245.8 2e-65
NP_203123 (OMIM: 123320,192600,601253,606072,60780 ( 151) 1037 245.8 2e-65
NP_001166366 (OMIM: 601047,606721,612526,615343) c ( 147) 703 169.3 2.1e-42
NP_001166368 (OMIM: 601047,606721,612526,615343) c ( 147) 703 169.3 2.1e-42
NP_001166367 (OMIM: 601047,606721,612526,615343) c ( 147) 703 169.3 2.1e-42
NP_001744 (OMIM: 601047,606721,612526,615343) cave ( 178) 703 169.4 2.4e-42
NP_001193676 (OMIM: 601048) caveolin-2 isoform b [ ( 149) 327 83.2 1.7e-16
NP_001224 (OMIM: 601048) caveolin-2 isoform a [Hom ( 162) 327 83.2 1.8e-16
NP_001193677 (OMIM: 601048) caveolin-2 isoform d [ ( 79) 169 46.8 8.5e-06
>>NP_001225 (OMIM: 123320,192600,601253,606072,607801,61 (151 aa)
initn: 1037 init1: 1037 opt: 1037 Z-score: 1295.5 bits: 245.8 E(85289): 2e-65
Smith-Waterman score: 1037; 100.0% identity (100.0% similar) in 151 aa overlap (1-151:1-151)
10 20 30 40 50 60
pF1KE3 MMAEEHTDLEAQIVKDIHCKEIDLVNRDPKNINEDIVKVDFEDVIAEPVGTYSFDGVWKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMAEEHTDLEAQIVKDIHCKEIDLVNRDPKNINEDIVKVDFEDVIAEPVGTYSFDGVWKV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 SYTTFTVSKYWCYRLLSTLLGVPLALLWGFLFACISFCHIWAVVPCIKSYLIEIQCISHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SYTTFTVSKYWCYRLLSTLLGVPLALLWGFLFACISFCHIWAVVPCIKSYLIEIQCISHI
70 80 90 100 110 120
130 140 150
pF1KE3 YSLCIRTFCNPLFAALGQVCSSIKVVLRKEV
:::::::::::::::::::::::::::::::
NP_001 YSLCIRTFCNPLFAALGQVCSSIKVVLRKEV
130 140 150
>>NP_203123 (OMIM: 123320,192600,601253,606072,607801,61 (151 aa)
initn: 1037 init1: 1037 opt: 1037 Z-score: 1295.5 bits: 245.8 E(85289): 2e-65
Smith-Waterman score: 1037; 100.0% identity (100.0% similar) in 151 aa overlap (1-151:1-151)
10 20 30 40 50 60
pF1KE3 MMAEEHTDLEAQIVKDIHCKEIDLVNRDPKNINEDIVKVDFEDVIAEPVGTYSFDGVWKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_203 MMAEEHTDLEAQIVKDIHCKEIDLVNRDPKNINEDIVKVDFEDVIAEPVGTYSFDGVWKV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 SYTTFTVSKYWCYRLLSTLLGVPLALLWGFLFACISFCHIWAVVPCIKSYLIEIQCISHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_203 SYTTFTVSKYWCYRLLSTLLGVPLALLWGFLFACISFCHIWAVVPCIKSYLIEIQCISHI
70 80 90 100 110 120
130 140 150
pF1KE3 YSLCIRTFCNPLFAALGQVCSSIKVVLRKEV
:::::::::::::::::::::::::::::::
NP_203 YSLCIRTFCNPLFAALGQVCSSIKVVLRKEV
130 140 150
>>NP_001166366 (OMIM: 601047,606721,612526,615343) caveo (147 aa)
initn: 708 init1: 678 opt: 703 Z-score: 882.3 bits: 169.3 E(85289): 2.1e-42
Smith-Waterman score: 703; 64.0% identity (87.3% similar) in 150 aa overlap (2-151:1-147)
10 20 30 40 50 60
pF1KE3 MMAEEHTDLEAQIVKDIHCKEIDLVNRDPKNINEDIVKVDFEDVIAEPVGTYSFDGVWKV
::.: : . : : : :::::::::::..:.:.::.::::::::: ::.::::.::.
NP_001 MADE---LSEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKA
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 SYTTFTVSKYWCYRLLSTLLGVPLALLWGFLFACISFCHIWAVVPCIKSYLIEIQCISHI
:.:::::.::: :::::.:.:.:.::.::. :: .:: :::::::::::.::::::::..
NP_001 SFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQCISRV
60 70 80 90 100 110
130 140 150
pF1KE3 YSLCIRTFCNPLFAALGQVCSSIKVVLRKEV
::. ..: :.::: :.:.. :.... :.::.
NP_001 YSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
120 130 140
>>NP_001166368 (OMIM: 601047,606721,612526,615343) caveo (147 aa)
initn: 708 init1: 678 opt: 703 Z-score: 882.3 bits: 169.3 E(85289): 2.1e-42
Smith-Waterman score: 703; 64.0% identity (87.3% similar) in 150 aa overlap (2-151:1-147)
10 20 30 40 50 60
pF1KE3 MMAEEHTDLEAQIVKDIHCKEIDLVNRDPKNINEDIVKVDFEDVIAEPVGTYSFDGVWKV
::.: : . : : : :::::::::::..:.:.::.::::::::: ::.::::.::.
NP_001 MADE---LSEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKA
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 SYTTFTVSKYWCYRLLSTLLGVPLALLWGFLFACISFCHIWAVVPCIKSYLIEIQCISHI
:.:::::.::: :::::.:.:.:.::.::. :: .:: :::::::::::.::::::::..
NP_001 SFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQCISRV
60 70 80 90 100 110
130 140 150
pF1KE3 YSLCIRTFCNPLFAALGQVCSSIKVVLRKEV
::. ..: :.::: :.:.. :.... :.::.
NP_001 YSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
120 130 140
>>NP_001166367 (OMIM: 601047,606721,612526,615343) caveo (147 aa)
initn: 708 init1: 678 opt: 703 Z-score: 882.3 bits: 169.3 E(85289): 2.1e-42
Smith-Waterman score: 703; 64.0% identity (87.3% similar) in 150 aa overlap (2-151:1-147)
10 20 30 40 50 60
pF1KE3 MMAEEHTDLEAQIVKDIHCKEIDLVNRDPKNINEDIVKVDFEDVIAEPVGTYSFDGVWKV
::.: : . : : : :::::::::::..:.:.::.::::::::: ::.::::.::.
NP_001 MADE---LSEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKA
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 SYTTFTVSKYWCYRLLSTLLGVPLALLWGFLFACISFCHIWAVVPCIKSYLIEIQCISHI
:.:::::.::: :::::.:.:.:.::.::. :: .:: :::::::::::.::::::::..
NP_001 SFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQCISRV
60 70 80 90 100 110
130 140 150
pF1KE3 YSLCIRTFCNPLFAALGQVCSSIKVVLRKEV
::. ..: :.::: :.:.. :.... :.::.
NP_001 YSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
120 130 140
>>NP_001744 (OMIM: 601047,606721,612526,615343) caveolin (178 aa)
initn: 708 init1: 678 opt: 703 Z-score: 881.3 bits: 169.4 E(85289): 2.4e-42
Smith-Waterman score: 703; 64.0% identity (87.3% similar) in 150 aa overlap (2-151:32-178)
10 20 30
pF1KE3 MMAEEHTDLEAQIVKDIHCKEIDLVNRDPKN
::.: : . : : : :::::::::::.
NP_001 SGGKYVDSEGHLYTVPIREQGNIYKPNNKAMADE---LSEKQVYDAHTKEIDLVNRDPKH
10 20 30 40 50
40 50 60 70 80 90
pF1KE3 INEDIVKVDFEDVIAEPVGTYSFDGVWKVSYTTFTVSKYWCYRLLSTLLGVPLALLWGFL
.:.:.::.::::::::: ::.::::.::.:.:::::.::: :::::.:.:.:.::.::.
NP_001 LNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIY
60 70 80 90 100 110
100 110 120 130 140 150
pF1KE3 FACISFCHIWAVVPCIKSYLIEIQCISHIYSLCIRTFCNPLFAALGQVCSSIKVVLRKEV
:: .:: :::::::::::.::::::::..::. ..: :.::: :.:.. :.... :.::.
NP_001 FAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI
120 130 140 150 160 170
>>NP_001193676 (OMIM: 601048) caveolin-2 isoform b [Homo (149 aa)
initn: 332 init1: 298 opt: 327 Z-score: 417.0 bits: 83.2 E(85289): 1.7e-16
Smith-Waterman score: 327; 39.2% identity (72.0% similar) in 125 aa overlap (26-150:26-149)
10 20 30 40 50 60
pF1KE3 MMAEEHTDLEAQIVKDIHCKEIDLVNRDPKNINEDIVKVDFEDVIAEPVGTYSFDGVWKV
.:::. .: . :. ::::::::: :.::: ::
NP_001 MDDDSYSHHSGLEYADPEKFADSDQDRDPHRLNSHL-KLGFEDVIAEPVTTHSFDKVWIC
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 SYTTFTVSKYWCYRLLSTLLGVPLALLWGFLFACISFCHIWAVVPCIKSYLIEIQCISHI
:.. : .::: :..:...:..:::.. :.::: .: ::: ..: .:. :. . .. :
NP_001 SHALFEISKYVMYKFLTVFLAIPLAFIAGILFATLSCLHIWILMPFVKTCLMVLPSVQTI
60 70 80 90 100 110
130 140 150
pF1KE3 YSLCIRTFCNPLFAALGQVCSSIKVVLRKEV
.. .. :: ...:. ::... : ..
NP_001 WKSVTDVIIAPLCTSVGRCFSSVSLQLSQD
120 130 140
>>NP_001224 (OMIM: 601048) caveolin-2 isoform a [Homo sa (162 aa)
initn: 332 init1: 298 opt: 327 Z-score: 416.5 bits: 83.2 E(85289): 1.8e-16
Smith-Waterman score: 327; 39.2% identity (72.0% similar) in 125 aa overlap (26-150:39-162)
10 20 30 40 50
pF1KE3 MMAEEHTDLEAQIVKDIHCKEIDLVNRDPKNINEDIVKVDFEDVIAEPVGTYSFD
.:::. .: . :. ::::::::: :.:::
NP_001 DVQLFMDDDSYSHHSGLEYADPEKFADSDQDRDPHRLNSHL-KLGFEDVIAEPVTTHSFD
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 GVWKVSYTTFTVSKYWCYRLLSTLLGVPLALLWGFLFACISFCHIWAVVPCIKSYLIEIQ
:: :.. : .::: :..:...:..:::.. :.::: .: ::: ..: .:. :. .
NP_001 KVWICSHALFEISKYVMYKFLTVFLAIPLAFIAGILFATLSCLHIWILMPFVKTCLMVLP
70 80 90 100 110 120
120 130 140 150
pF1KE3 CISHIYSLCIRTFCNPLFAALGQVCSSIKVVLRKEV
.. :.. .. :: ...:. ::... : ..
NP_001 SVQTIWKSVTDVIIAPLCTSVGRCFSSVSLQLSQD
130 140 150 160
>>NP_001193677 (OMIM: 601048) caveolin-2 isoform d [Homo (79 aa)
initn: 155 init1: 140 opt: 169 Z-score: 225.1 bits: 46.8 E(85289): 8.5e-06
Smith-Waterman score: 169; 30.8% identity (71.8% similar) in 78 aa overlap (73-150:2-79)
50 60 70 80 90 100
pF1KE3 DVIAEPVGTYSFDGVWKVSYTTFTVSKYWCYRLLSTLLGVPLALLWGFLFACISFCHIWA
:..:...:..:::.. :.::: .: :::
NP_001 MYKFLTVFLAIPLAFIAGILFATLSCLHIWI
10 20 30
110 120 130 140 150
pF1KE3 VVPCIKSYLIEIQCISHIYSLCIRTFCNPLFAALGQVCSSIKVVLRKEV
..: .:. :. . .. :.. .. :: ...:. ::... : ..
NP_001 LMPFVKTCLMVLPSVQTIWKSVTDVIIAPLCTSVGRCFSSVSLQLSQD
40 50 60 70
151 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 22:53:30 2016 done: Sat Nov 5 22:53:31 2016
Total Scan time: 4.420 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]