Result of FASTA (omim) for
pFN21AE3014
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3014, 104 aa
1>>>pF1KE3014 104 - 104 aa - 104 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9060+/-0.000283; mu= 10.7828+/- 0.018
mean_var=50.0982+/- 9.837, 0's: 0 Z-trim(117.3): 20 B-trim: 0 in 0/54
Lambda= 0.181202
statistics sampled from 29228 (29248) to 29228 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.75), E-opt: 0.2 (0.343), width: 16
Scan time: 4.640
The best scores are: opt bits E(85289)
NP_002611 (OMIM: 173461) platelet factor 4 variant ( 104) 660 179.5 8.3e-46
NP_002610 (OMIM: 173460) platelet factor 4 precurs ( 101) 531 145.8 1.1e-35
XP_005265753 (OMIM: 173460) PREDICTED: platelet fa ( 110) 440 122.0 1.8e-28
NP_001502 (OMIM: 155730) growth-regulated alpha pr ( 107) 244 70.8 4.6e-13
NP_002695 (OMIM: 121010) platelet basic protein pr ( 128) 237 69.0 1.9e-12
NP_002985 (OMIM: 600324) C-X-C motif chemokine 5 p ( 114) 233 67.9 3.6e-12
NP_002080 (OMIM: 139110) C-X-C motif chemokine 2 p ( 107) 225 65.8 1.5e-11
NP_002984 (OMIM: 138965) C-X-C motif chemokine 6 p ( 114) 221 64.8 3.2e-11
NP_002081 (OMIM: 139111) C-X-C motif chemokine 3 p ( 107) 207 61.1 3.8e-10
NP_000575 (OMIM: 146930) interleukin-8 precursor [ ( 99) 183 54.8 2.7e-08
NP_001556 (OMIM: 147310) C-X-C motif chemokine 10 ( 98) 148 45.7 1.5e-05
NP_002407 (OMIM: 601704) C-X-C motif chemokine 9 p ( 125) 127 40.2 0.00086
NP_006410 (OMIM: 605149) C-X-C motif chemokine 13 ( 109) 122 38.9 0.0019
XP_006714126 (OMIM: 605149) PREDICTED: C-X-C motif ( 109) 122 38.9 0.0019
NP_004878 (OMIM: 604186) C-X-C motif chemokine 14 ( 111) 117 37.6 0.0047
>>NP_002611 (OMIM: 173461) platelet factor 4 variant pre (104 aa)
initn: 660 init1: 660 opt: 660 Z-score: 943.4 bits: 179.5 E(85289): 8.3e-46
Smith-Waterman score: 660; 100.0% identity (100.0% similar) in 104 aa overlap (1-104:1-104)
10 20 30 40 50 60
pF1KE3 MSSAARSRLTRATRQEMLFLALLLLPVVVAFARAEAEEDGDLQCLCVKTTSQVRPRHITS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MSSAARSRLTRATRQEMLFLALLLLPVVVAFARAEAEEDGDLQCLCVKTTSQVRPRHITS
10 20 30 40 50 60
70 80 90 100
pF1KE3 LEVIKAGPHCPTAQLIATLKNGRKICLDLQALLYKKIIKEHLES
::::::::::::::::::::::::::::::::::::::::::::
NP_002 LEVIKAGPHCPTAQLIATLKNGRKICLDLQALLYKKIIKEHLES
70 80 90 100
>>NP_002610 (OMIM: 173460) platelet factor 4 precursor [ (101 aa)
initn: 542 init1: 529 opt: 531 Z-score: 761.3 bits: 145.8 E(85289): 1.1e-35
Smith-Waterman score: 531; 84.6% identity (89.4% similar) in 104 aa overlap (1-104:1-101)
10 20 30 40 50 60
pF1KE3 MSSAARSRLTRATRQEMLFLALLLLPVVVAFARAEAEEDGDLQCLCVKTTSQVRPRHITS
::::: :.: .:::.:::::.::::: :::::::::::::::::::::::::::
NP_002 MSSAAG---FCASRPGLLFLGLLLLPLVVAFASAEAEEDGDLQCLCVKTTSQVRPRHITS
10 20 30 40 50
70 80 90 100
pF1KE3 LEVIKAGPHCPTAQLIATLKNGRKICLDLQALLYKKIIKEHLES
::::::::::::::::::::::::::::::: :::::::. :::
NP_002 LEVIKAGPHCPTAQLIATLKNGRKICLDLQAPLYKKIIKKLLES
60 70 80 90 100
>>XP_005265753 (OMIM: 173460) PREDICTED: platelet factor (110 aa)
initn: 440 init1: 440 opt: 440 Z-score: 632.2 bits: 122.0 E(85289): 1.8e-28
Smith-Waterman score: 440; 95.8% identity (97.2% similar) in 71 aa overlap (34-104:40-110)
10 20 30 40 50 60
pF1KE3 AARSRLTRATRQEMLFLALLLLPVVVAFARAEAEEDGDLQCLCVKTTSQVRPRHITSLEV
::::::::::::::::::::::::::::::
XP_005 PAECLATVPGAAPAPPTWLEQLLSGGGVIYAEAEEDGDLQCLCVKTTSQVRPRHITSLEV
10 20 30 40 50 60
70 80 90 100
pF1KE3 IKAGPHCPTAQLIATLKNGRKICLDLQALLYKKIIKEHLES
:::::::::::::::::::::::::::: :::::::. :::
XP_005 IKAGPHCPTAQLIATLKNGRKICLDLQAPLYKKIIKKLLES
70 80 90 100 110
>>NP_001502 (OMIM: 155730) growth-regulated alpha protei (107 aa)
initn: 182 init1: 141 opt: 244 Z-score: 355.5 bits: 70.8 E(85289): 4.6e-13
Smith-Waterman score: 244; 43.1% identity (71.6% similar) in 102 aa overlap (5-104:2-103)
10 20 30 40 50
pF1KE3 MSSAARSRLTRA-TRQEMLFLALLLLPVVVAFARAE-AEEDGDLQCLCVKTTSQVRPRHI
::. :. : . ..: .::::: .:.: :: : .:.: :..: . ..:..:
NP_001 MARAALSAAPSNPRLLRVALLLLLLVAAGRRAAGASVATELRCQCLQTLQGIHPKNI
10 20 30 40 50
60 70 80 90 100
pF1KE3 TSLEVIKAGPHCPTAQLIATLKNGRKICLDLQALLYKKIIKEHLES
:..: . :::: ...::::::::: ::. . . ::::.. :.:
NP_001 QSVNVKSPGPHCAQTEVIATLKNGRKACLNPASPIVKKIIEKMLNSDKSN
60 70 80 90 100
>>NP_002695 (OMIM: 121010) platelet basic protein prepro (128 aa)
initn: 217 init1: 196 opt: 237 Z-score: 344.3 bits: 69.0 E(85289): 1.9e-12
Smith-Waterman score: 241; 43.6% identity (70.3% similar) in 101 aa overlap (15-102:21-121)
10 20 30 40
pF1KE3 MSSAARSRLTRATRQEMLFLALLLLPVVVA--------FARAEAEE-DGDL---
: .:.:.::: .. . .:... : :.::
NP_002 MSLRLDTTPSCNSARPLHALQVLLLLSLLLTALASSTKGQTKRNLAKGKEESLDSDLYAE
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 -QCLCVKTTSQVRPRHITSLEVIKAGPHCPTAQLIATLKNGRKICLDLQALLYKKIIKEH
.:.:.:::: ..:..: ::::: : :: ...:::::.::::::: .: :::....
NP_002 LRCMCIKTTSGIHPKNIQSLEVIGKGTHCNQVEVIATLKDGRKICLDPDAPRIKKIVQKK
70 80 90 100 110 120
pF1KE3 LES
:
NP_002 LAGDESAD
>>NP_002985 (OMIM: 600324) C-X-C motif chemokine 5 precu (114 aa)
initn: 206 init1: 174 opt: 233 Z-score: 339.5 bits: 67.9 E(85289): 3.6e-12
Smith-Waterman score: 233; 38.8% identity (68.0% similar) in 103 aa overlap (2-103:6-108)
10 20 30 40 50
pF1KE3 MSSAARSRLTRATRQEMLFLALLLL-PVVVAFARAEAEEDGDLQCLCVKTTSQVRP
: ::: .. .: : ::: : .: : : .:.:.:..::. :.:
NP_002 MSLLSSRAARVPGPSSSLCALLVLLLLLTQPGPIASAGPAAAVLRELRCVCLQTTQGVHP
10 20 30 40 50 60
60 70 80 90 100
pF1KE3 RHITSLEVIKAGPHCPTAQLIATLKNGRKICLDLQALLYKKIIKEHLES
. :..:.:. ::.: ....:.::::..:::: .: . ::.:.. :.
NP_002 KMISNLQVFAIGPQCSKVEVVASLKNGKEICLDPEAPFLKKVIQKILDGGNKEN
70 80 90 100 110
>>NP_002080 (OMIM: 139110) C-X-C motif chemokine 2 precu (107 aa)
initn: 167 init1: 133 opt: 225 Z-score: 328.6 bits: 65.8 E(85289): 1.5e-11
Smith-Waterman score: 225; 40.2% identity (70.6% similar) in 102 aa overlap (5-104:2-103)
10 20 30 40 50
pF1KE3 MSSAARSRLTRA-TRQEMLFLALLLLPVVVAFARAE-AEEDGDLQCLCVKTTSQVRPRHI
::. :. : . ..: .::::: .:.: :: : .:.: :..: . .. ..:
NP_002 MARATLSAAPSNPRLLRVALLLLLLVAASRRAAGAPLATELRCQCLQTLQGIHLKNI
10 20 30 40 50
60 70 80 90 100
pF1KE3 TSLEVIKAGPHCPTAQLIATLKNGRKICLDLQALLYKKIIKEHLES
:..: . :::: ...:::::::.: ::. . . ::::.. :..
NP_002 QSVKVKSPGPHCAQTEVIATLKNGQKACLNPASPMVKKIIEKMLKNGKSN
60 70 80 90 100
>>NP_002984 (OMIM: 138965) C-X-C motif chemokine 6 precu (114 aa)
initn: 199 init1: 141 opt: 221 Z-score: 322.5 bits: 64.8 E(85289): 3.2e-11
Smith-Waterman score: 221; 37.5% identity (66.3% similar) in 104 aa overlap (2-104:6-109)
10 20 30 40 50
pF1KE3 MSSAARSRLTRATRQEMLFLALLLLPV-VVAFARAEAEEDGDLQCLCVKTTSQVRP
: ::: .. .: : ::: : .: : . .:.: :...: .: :
NP_002 MSLPSSRAARVPGPSGSLCALLALLLLLTPPGPLASAGPVSAVLTELRCTCLRVTLRVNP
10 20 30 40 50 60
60 70 80 90 100
pF1KE3 RHITSLEVIKAGPHCPTAQLIATLKNGRKICLDLQALLYKKIIKEHLES
. : .:.:. :::.: ....:.::::...::: .: . ::.:.. :.:
NP_002 KTIGKLQVFPAGPQCSKVEVVASLKNGKQVCLDPEAPFLKKVIQKILDSGNKKN
70 80 90 100 110
>>NP_002081 (OMIM: 139111) C-X-C motif chemokine 3 precu (107 aa)
initn: 182 init1: 126 opt: 207 Z-score: 303.2 bits: 61.1 E(85289): 3.8e-10
Smith-Waterman score: 207; 39.0% identity (70.0% similar) in 100 aa overlap (5-102:2-101)
10 20 30 40 50
pF1KE3 MSSAARSRLTRA-TRQEMLFLALLLLPVVVAFARAE-AEEDGDLQCLCVKTTSQVRPRHI
:.. :. : . ..: .::::: .:.: :: : .:.: :..: . .. ..:
NP_002 MAHATLSAAPSNPRLLRVALLLLLLVAASRRAAGASVVTELRCQCLQTLQGIHLKNI
10 20 30 40 50
60 70 80 90 100
pF1KE3 TSLEVIKAGPHCPTAQLIATLKNGRKICLDLQALLYKKIIKEHLES
:..: . :::: ...:::::::.: ::. . . .:::.. :
NP_002 QSVNVRSPGPHCAQTEVIATLKNGKKACLNPASPMVQKIIEKILNKGSTN
60 70 80 90 100
>>NP_000575 (OMIM: 146930) interleukin-8 precursor [Homo (99 aa)
initn: 139 init1: 131 opt: 183 Z-score: 269.8 bits: 54.8 E(85289): 2.7e-08
Smith-Waterman score: 183; 28.3% identity (69.6% similar) in 92 aa overlap (13-103:3-94)
10 20 30 40 50
pF1KE3 MSSAARSRLTRATRQEMLFLALLLLPVVVAFARAEAEEDGDLQCLCVKTTSQ-VRPRHIT
.. . .:: .:. ... . . . .:.: :.:: :. .:. :
NP_000 MTSKLAVALLAAFLISAALCEGAVLPRSAKELRCQCIKTYSKPFHPKFIK
10 20 30 40 50
60 70 80 90 100
pF1KE3 SLEVIKAGPHCPTAQLIATLKNGRKICLDLQALLYKKIIKEHLES
:.::..:::: ....:. :..::..::: . ...... :.
NP_000 ELRVIESGPHCANTEIIVKLSDGRELCLDPKENWVQRVVEKFLKRAENS
60 70 80 90
104 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 04:28:29 2016 done: Sun Nov 6 04:28:30 2016
Total Scan time: 4.640 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]