Result of FASTA (omim) for
pFN21AE2741
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2741, 359 aa
1>>>pF1KE2741 359 - 359 aa - 359 aa
Library: /omim/omim.rfq.tfa
65951994 residues in 93482 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1772+/-0.000348; mu= 17.3906+/- 0.021
mean_var=65.4286+/-13.236, 0's: 0 Z-trim(112.8): 10 B-trim: 0 in 0/54
Lambda= 0.158559
statistics sampled from 22892 (22899) to 22892 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.632), E-opt: 0.2 (0.245), width: 16
Scan time: 3.840
The best scores are: opt bits E(93482)
NP_061819 (OMIM: 605202,610442) sialic acid syntha ( 359) 2414 561.1 1.5e-159
XP_011517089 (OMIM: 605202,610442) sialic acid syn ( 243) 1592 373.0 4.3e-103
XP_024303342 (OMIM: 605202,610442) sialic acid syn ( 243) 1592 373.0 4.3e-103
XP_011517090 (OMIM: 605202,610442) sialic acid syn ( 234) 1388 326.3 4.7e-89
XP_016870300 (OMIM: 605202,610442) sialic acid syn ( 218) 1373 322.8 4.8e-88
>>NP_061819 (OMIM: 605202,610442) sialic acid synthase [ (359 aa)
initn: 2414 init1: 2414 opt: 2414 Z-score: 2986.2 bits: 561.1 E(93482): 1.5e-159
Smith-Waterman score: 2414; 100.0% identity (100.0% similar) in 359 aa overlap (1-359:1-359)
10 20 30 40 50 60
pF1KE2 MPLELELCPGRWVGGQHPCFIIAEIGQNHQGDLDVAKRMIRMAKECGADCAKFQKSELEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 MPLELELCPGRWVGGQHPCFIIAEIGQNHQGDLDVAKRMIRMAKECGADCAKFQKSELEF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 KFNRKALERPYTSKHSWGKTYGEHKRHLEFSHDQYRELQRYAEEVGIFFTASGMDEMAVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 KFNRKALERPYTSKHSWGKTYGEHKRHLEFSHDQYRELQRYAEEVGIFFTASGMDEMAVE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 FLHELNVPFFKVGSGDTNNFPYLEKTAKKGRPMVISSGMQSMDTMKQVYQIVKPLNPNFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 FLHELNVPFFKVGSGDTNNFPYLEKTAKKGRPMVISSGMQSMDTMKQVYQIVKPLNPNFC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 FLQCTSAYPLQPEDVNLRVISEYQKLFPDIPIGYSGHETGIAISVAAVALGAKVLERHIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 FLQCTSAYPLQPEDVNLRVISEYQKLFPDIPIGYSGHETGIAISVAAVALGAKVLERHIT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 LDKTWKGSDHSASLEPGELAELVRSVRLVERALGSPTKQLLPCEMACNEKLGKSVVAKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 LDKTWKGSDHSASLEPGELAELVRSVRLVERALGSPTKQLLPCEMACNEKLGKSVVAKVK
250 260 270 280 290 300
310 320 330 340 350
pF1KE2 IPEGTILTMDMLTVKVGEPKGYPPEDIFNLVGKKVLVTVEEDDTIMEELVDNHGKKIKS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 IPEGTILTMDMLTVKVGEPKGYPPEDIFNLVGKKVLVTVEEDDTIMEELVDNHGKKIKS
310 320 330 340 350
>>XP_011517089 (OMIM: 605202,610442) sialic acid synthas (243 aa)
initn: 1592 init1: 1592 opt: 1592 Z-score: 1972.5 bits: 373.0 E(93482): 4.3e-103
Smith-Waterman score: 1592; 100.0% identity (100.0% similar) in 243 aa overlap (117-359:1-243)
90 100 110 120 130 140
pF1KE2 HLEFSHDQYRELQRYAEEVGIFFTASGMDEMAVEFLHELNVPFFKVGSGDTNNFPYLEKT
::::::::::::::::::::::::::::::
XP_011 MAVEFLHELNVPFFKVGSGDTNNFPYLEKT
10 20 30
150 160 170 180 190 200
pF1KE2 AKKGRPMVISSGMQSMDTMKQVYQIVKPLNPNFCFLQCTSAYPLQPEDVNLRVISEYQKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKKGRPMVISSGMQSMDTMKQVYQIVKPLNPNFCFLQCTSAYPLQPEDVNLRVISEYQKL
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE2 FPDIPIGYSGHETGIAISVAAVALGAKVLERHITLDKTWKGSDHSASLEPGELAELVRSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FPDIPIGYSGHETGIAISVAAVALGAKVLERHITLDKTWKGSDHSASLEPGELAELVRSV
100 110 120 130 140 150
270 280 290 300 310 320
pF1KE2 RLVERALGSPTKQLLPCEMACNEKLGKSVVAKVKIPEGTILTMDMLTVKVGEPKGYPPED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLVERALGSPTKQLLPCEMACNEKLGKSVVAKVKIPEGTILTMDMLTVKVGEPKGYPPED
160 170 180 190 200 210
330 340 350
pF1KE2 IFNLVGKKVLVTVEEDDTIMEELVDNHGKKIKS
:::::::::::::::::::::::::::::::::
XP_011 IFNLVGKKVLVTVEEDDTIMEELVDNHGKKIKS
220 230 240
>>XP_024303342 (OMIM: 605202,610442) sialic acid synthas (243 aa)
initn: 1592 init1: 1592 opt: 1592 Z-score: 1972.5 bits: 373.0 E(93482): 4.3e-103
Smith-Waterman score: 1592; 100.0% identity (100.0% similar) in 243 aa overlap (117-359:1-243)
90 100 110 120 130 140
pF1KE2 HLEFSHDQYRELQRYAEEVGIFFTASGMDEMAVEFLHELNVPFFKVGSGDTNNFPYLEKT
::::::::::::::::::::::::::::::
XP_024 MAVEFLHELNVPFFKVGSGDTNNFPYLEKT
10 20 30
150 160 170 180 190 200
pF1KE2 AKKGRPMVISSGMQSMDTMKQVYQIVKPLNPNFCFLQCTSAYPLQPEDVNLRVISEYQKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 AKKGRPMVISSGMQSMDTMKQVYQIVKPLNPNFCFLQCTSAYPLQPEDVNLRVISEYQKL
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE2 FPDIPIGYSGHETGIAISVAAVALGAKVLERHITLDKTWKGSDHSASLEPGELAELVRSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 FPDIPIGYSGHETGIAISVAAVALGAKVLERHITLDKTWKGSDHSASLEPGELAELVRSV
100 110 120 130 140 150
270 280 290 300 310 320
pF1KE2 RLVERALGSPTKQLLPCEMACNEKLGKSVVAKVKIPEGTILTMDMLTVKVGEPKGYPPED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_024 RLVERALGSPTKQLLPCEMACNEKLGKSVVAKVKIPEGTILTMDMLTVKVGEPKGYPPED
160 170 180 190 200 210
330 340 350
pF1KE2 IFNLVGKKVLVTVEEDDTIMEELVDNHGKKIKS
:::::::::::::::::::::::::::::::::
XP_024 IFNLVGKKVLVTVEEDDTIMEELVDNHGKKIKS
220 230 240
>>XP_011517090 (OMIM: 605202,610442) sialic acid synthas (234 aa)
initn: 1387 init1: 1387 opt: 1388 Z-score: 1720.5 bits: 326.3 E(93482): 4.7e-89
Smith-Waterman score: 1388; 96.8% identity (97.7% similar) in 220 aa overlap (140-359:15-234)
110 120 130 140 150 160
pF1KE2 TASGMDEMAVEFLHELNVPFFKVGSGDTNNFPYLEKTAKKGRPMVISSGMQSMDTMKQVY
: .. ::::::::::::::::::::::
XP_011 MFHFSKLDLETLIIFLIWKRQPKKGRPMVISSGMQSMDTMKQVY
10 20 30 40
170 180 190 200 210 220
pF1KE2 QIVKPLNPNFCFLQCTSAYPLQPEDVNLRVISEYQKLFPDIPIGYSGHETGIAISVAAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QIVKPLNPNFCFLQCTSAYPLQPEDVNLRVISEYQKLFPDIPIGYSGHETGIAISVAAVA
50 60 70 80 90 100
230 240 250 260 270 280
pF1KE2 LGAKVLERHITLDKTWKGSDHSASLEPGELAELVRSVRLVERALGSPTKQLLPCEMACNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGAKVLERHITLDKTWKGSDHSASLEPGELAELVRSVRLVERALGSPTKQLLPCEMACNE
110 120 130 140 150 160
290 300 310 320 330 340
pF1KE2 KLGKSVVAKVKIPEGTILTMDMLTVKVGEPKGYPPEDIFNLVGKKVLVTVEEDDTIMEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLGKSVVAKVKIPEGTILTMDMLTVKVGEPKGYPPEDIFNLVGKKVLVTVEEDDTIMEEL
170 180 190 200 210 220
350
pF1KE2 VDNHGKKIKS
::::::::::
XP_011 VDNHGKKIKS
230
>>XP_016870300 (OMIM: 605202,610442) sialic acid synthas (218 aa)
initn: 1373 init1: 1373 opt: 1373 Z-score: 1702.4 bits: 322.8 E(93482): 4.8e-88
Smith-Waterman score: 1373; 100.0% identity (100.0% similar) in 210 aa overlap (150-359:9-218)
120 130 140 150 160 170
pF1KE2 EFLHELNVPFFKVGSGDTNNFPYLEKTAKKGRPMVISSGMQSMDTMKQVYQIVKPLNPNF
::::::::::::::::::::::::::::::
XP_016 MVLVLDYSGRPMVISSGMQSMDTMKQVYQIVKPLNPNF
10 20 30
180 190 200 210 220 230
pF1KE2 CFLQCTSAYPLQPEDVNLRVISEYQKLFPDIPIGYSGHETGIAISVAAVALGAKVLERHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CFLQCTSAYPLQPEDVNLRVISEYQKLFPDIPIGYSGHETGIAISVAAVALGAKVLERHI
40 50 60 70 80 90
240 250 260 270 280 290
pF1KE2 TLDKTWKGSDHSASLEPGELAELVRSVRLVERALGSPTKQLLPCEMACNEKLGKSVVAKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLDKTWKGSDHSASLEPGELAELVRSVRLVERALGSPTKQLLPCEMACNEKLGKSVVAKV
100 110 120 130 140 150
300 310 320 330 340 350
pF1KE2 KIPEGTILTMDMLTVKVGEPKGYPPEDIFNLVGKKVLVTVEEDDTIMEELVDNHGKKIKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KIPEGTILTMDMLTVKVGEPKGYPPEDIFNLVGKKVLVTVEEDDTIMEELVDNHGKKIKS
160 170 180 190 200 210
359 residues in 1 query sequences
65951994 residues in 93482 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Jun 19 14:23:45 2019 done: Wed Jun 19 14:23:45 2019
Total Scan time: 3.840 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]