Result of FASTA (omim) for
pFN21AE2731
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2731, 324 aa
1>>>pF1KE2731 324 - 324 aa - 324 aa
Library: /omim/omim.rfq.tfa
64848753 residues in 91609 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.1622+/-0.000588; mu= -12.4409+/- 0.034
mean_var=825.9666+/-193.357, 0's: 0 Z-trim(117.6): 882 B-trim: 1815 in 1/53
Lambda= 0.044627
statistics sampled from 29562 (30864) to 29562 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.698), E-opt: 0.2 (0.337), width: 16
Scan time: 6.330
The best scores are: opt bits E(91609)
NP_112557 (OMIM: 603309,617360) cyclin-dependent k (1452) 2093 151.6 1e-35
NP_003709 (OMIM: 603309,617360) cyclin-dependent k (1512) 2093 151.6 1e-35
XP_005257515 (OMIM: 615514) cyclin-dependent kinas (1256) 1746 129.1 5e-29
XP_016880242 (OMIM: 615514) cyclin-dependent kinas (1261) 1746 129.1 5e-29
XP_016880239 (OMIM: 615514) cyclin-dependent kinas (1262) 1746 129.1 5e-29
XP_011523209 (OMIM: 615514) cyclin-dependent kinas (1262) 1746 129.1 5e-29
XP_016880240 (OMIM: 615514) cyclin-dependent kinas (1262) 1746 129.1 5e-29
XP_016880241 (OMIM: 615514) cyclin-dependent kinas (1262) 1746 129.1 5e-29
XP_011523198 (OMIM: 615514) cyclin-dependent kinas (1393) 1746 129.2 5.3e-29
XP_024306569 (OMIM: 615514) cyclin-dependent kinas (1393) 1746 129.2 5.3e-29
XP_011523202 (OMIM: 615514) cyclin-dependent kinas (1393) 1746 129.2 5.3e-29
XP_011523207 (OMIM: 615514) cyclin-dependent kinas (1393) 1746 129.2 5.3e-29
XP_016880238 (OMIM: 615514) cyclin-dependent kinas (1393) 1746 129.2 5.3e-29
XP_011523208 (OMIM: 615514) cyclin-dependent kinas (1393) 1746 129.2 5.3e-29
XP_011523199 (OMIM: 615514) cyclin-dependent kinas (1393) 1746 129.2 5.3e-29
XP_011523203 (OMIM: 615514) cyclin-dependent kinas (1393) 1746 129.2 5.3e-29
XP_011523201 (OMIM: 615514) cyclin-dependent kinas (1393) 1746 129.2 5.3e-29
XP_011523205 (OMIM: 615514) cyclin-dependent kinas (1393) 1746 129.2 5.3e-29
XP_011523204 (OMIM: 615514) cyclin-dependent kinas (1393) 1746 129.2 5.3e-29
XP_011523195 (OMIM: 615514) cyclin-dependent kinas (1393) 1746 129.2 5.3e-29
XP_016880237 (OMIM: 615514) cyclin-dependent kinas (1393) 1746 129.2 5.3e-29
XP_016880236 (OMIM: 615514) cyclin-dependent kinas (1393) 1746 129.2 5.3e-29
XP_011523197 (OMIM: 615514) cyclin-dependent kinas (1393) 1746 129.2 5.3e-29
XP_011523196 (OMIM: 615514) cyclin-dependent kinas (1393) 1746 129.2 5.3e-29
XP_011523200 (OMIM: 615514) cyclin-dependent kinas (1393) 1746 129.2 5.3e-29
NP_055898 (OMIM: 615514) cyclin-dependent kinase 1 (1481) 1746 129.2 5.5e-29
XP_005257513 (OMIM: 615514) cyclin-dependent kinas (1489) 1746 129.2 5.5e-29
NP_057591 (OMIM: 615514) cyclin-dependent kinase 1 (1490) 1746 129.2 5.5e-29
XP_011513899 (OMIM: 603309,617360) cyclin-dependen ( 905) 1692 125.4 4.8e-28
XP_016868240 (OMIM: 603309,617360) cyclin-dependen (1482) 1692 125.8 6.1e-28
XP_016868239 (OMIM: 603309,617360) cyclin-dependen (1542) 1692 125.8 6.2e-28
XP_011523194 (OMIM: 615514) cyclin-dependent kinas (1464) 1599 119.8 3.8e-26
NP_001252 (OMIM: 603251) cyclin-dependent kinase 9 ( 372) 802 67.5 5.4e-11
NP_001250 (OMIM: 603368,616080) cyclin-dependent k ( 326) 582 53.2 9.3e-07
XP_006715898 (OMIM: 603368,616080) cyclin-dependen ( 326) 582 53.2 9.3e-07
NP_001138778 (OMIM: 603368,616080) cyclin-dependen ( 326) 582 53.2 9.3e-07
NP_000066 (OMIM: 123829,609048) cyclin-dependent k ( 303) 550 51.1 3.8e-06
XP_016879299 (OMIM: 603464,617694) cyclin-dependen ( 272) 528 49.6 9.5e-06
NP_443713 (OMIM: 603464,617694) cyclin-dependent k ( 272) 528 49.6 9.5e-06
NP_001092003 (OMIM: 603464,617694) cyclin-dependen ( 283) 528 49.6 9.7e-06
XP_016879298 (OMIM: 603464,617694) cyclin-dependen ( 283) 528 49.6 9.7e-06
NP_001153839 (OMIM: 603464,617694) cyclin-dependen ( 289) 528 49.6 9.8e-06
XP_016879297 (OMIM: 603464,617694) cyclin-dependen ( 289) 528 49.6 9.8e-06
NP_620603 (OMIM: 602521) mitogen-activated protein ( 816) 532 50.6 1.4e-05
NP_620602 (OMIM: 602521) mitogen-activated protein ( 816) 532 50.6 1.4e-05
NP_002740 (OMIM: 602521) mitogen-activated protein ( 816) 532 50.6 1.4e-05
XP_016879295 (OMIM: 603464,617694) cyclin-dependen ( 355) 522 49.4 1.4e-05
XP_006721621 (OMIM: 602521) mitogen-activated prot ( 822) 527 50.3 1.7e-05
XP_006721622 (OMIM: 602521) mitogen-activated prot ( 822) 527 50.3 1.7e-05
XP_006721620 (OMIM: 602521) mitogen-activated prot ( 822) 527 50.3 1.7e-05
>>NP_112557 (OMIM: 603309,617360) cyclin-dependent kinas (1452 aa)
initn: 2093 init1: 2093 opt: 2093 Z-score: 762.8 bits: 151.6 E(91609): 1e-35
Smith-Waterman score: 2093; 100.0% identity (100.0% similar) in 312 aa overlap (1-312:615-926)
10 20 30
pF1KE2 MLPEDKEADSLRGNISVKAVKKEVEKKLRC
::::::::::::::::::::::::::::::
NP_112 KPLTPSIGAKEKEQHVALVTSTLPPLPLPPMLPEDKEADSLRGNISVKAVKKEVEKKLRC
590 600 610 620 630 640
40 50 60 70 80 90
pF1KE2 LLADLPLPPELPGGDDLSKSPEEKKTATQLHSKRRPKICGPRYGETKEKDIDWGKRCVDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 LLADLPLPPELPGGDDLSKSPEEKKTATQLHSKRRPKICGPRYGETKEKDIDWGKRCVDK
650 660 670 680 690 700
100 110 120 130 140 150
pF1KE2 FDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 FDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSI
710 720 730 740 750 760
160 170 180 190 200 210
pF1KE2 INMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 INMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEG
770 780 790 800 810 820
220 230 240 250 260 270
pF1KE2 LDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 LDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPEL
830 840 850 860 870 880
280 290 300 310 320
pF1KE2 LLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELIRHEENEVSDKQI
::::::::::::::::::::::::::::::::::::::::::
NP_112 LLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIKL
890 900 910 920 930 940
NP_112 PYFNTMKPKKQYRRKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRDVEPS
950 960 970 980 990 1000
>>NP_003709 (OMIM: 603309,617360) cyclin-dependent kinas (1512 aa)
initn: 2093 init1: 2093 opt: 2093 Z-score: 762.6 bits: 151.6 E(91609): 1e-35
Smith-Waterman score: 2093; 100.0% identity (100.0% similar) in 312 aa overlap (1-312:615-926)
10 20 30
pF1KE2 MLPEDKEADSLRGNISVKAVKKEVEKKLRC
::::::::::::::::::::::::::::::
NP_003 KPLTPSIGAKEKEQHVALVTSTLPPLPLPPMLPEDKEADSLRGNISVKAVKKEVEKKLRC
590 600 610 620 630 640
40 50 60 70 80 90
pF1KE2 LLADLPLPPELPGGDDLSKSPEEKKTATQLHSKRRPKICGPRYGETKEKDIDWGKRCVDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LLADLPLPPELPGGDDLSKSPEEKKTATQLHSKRRPKICGPRYGETKEKDIDWGKRCVDK
650 660 670 680 690 700
100 110 120 130 140 150
pF1KE2 FDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 FDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSI
710 720 730 740 750 760
160 170 180 190 200 210
pF1KE2 INMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 INMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEG
770 780 790 800 810 820
220 230 240 250 260 270
pF1KE2 LDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPEL
830 840 850 860 870 880
280 290 300 310 320
pF1KE2 LLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELIRHEENEVSDKQI
::::::::::::::::::::::::::::::::::::::::::
NP_003 LLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIKL
890 900 910 920 930 940
NP_003 PYFNTMKPKKQYRRKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRDVEPS
950 960 970 980 990 1000
>>XP_005257515 (OMIM: 615514) cyclin-dependent kinase 12 (1256 aa)
initn: 1673 init1: 1577 opt: 1746 Z-score: 642.6 bits: 129.1 E(91609): 5e-29
Smith-Waterman score: 1746; 83.2% identity (90.5% similar) in 315 aa overlap (1-312:635-948)
10 20 30
pF1KE2 MLPEDKEADSLRGNISVKAVKKEVEKKLRC
.:: : . :: . .. : :::: :.. :
XP_005 VQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQRTRH
610 620 630 640 650 660
40 50 60 70 80
pF1KE2 LLADLPLPPELPGGDDLSK--SPEEKK-TATQLHSKRRPKICGPRYGETKEKDIDWGKRC
::.:::::::::::: :: ::: : : : :.::::: ::::: .. . ::::::
XP_005 LLTDLPLPPELPGGD-LSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWGKRC
670 680 690 700 710 720
90 100 110 120 130 140
pF1KE2 VDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTH
:::::::::::::::::::::.::::::.::::::::::::::::::::::::::::: :
XP_005 VDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIH
730 740 750 760 770 780
150 160 170 180 190 200
pF1KE2 QSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQL
.:..:::::::::.::::::::::::::::::::::::::::::::::.:.::::::.::
XP_005 RSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQL
790 800 810 820 830 840
210 220 230 240 250 260
pF1KE2 MEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRP
::::.::::::::::::::::::::: ::::::::::::::.::::::::::::::::::
XP_005 MEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRP
850 860 870 880 890 900
270 280 290 300 310 320
pF1KE2 PELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELIRHEENEVSDKQI
:::::::::::::::::::::::::::::::::::: ::::::::
XP_005 PELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDV
910 920 930 940 950 960
XP_005 IKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDV
970 980 990 1000 1010 1020
>>XP_016880242 (OMIM: 615514) cyclin-dependent kinase 12 (1261 aa)
initn: 1673 init1: 1577 opt: 1746 Z-score: 642.6 bits: 129.1 E(91609): 5e-29
Smith-Waterman score: 1746; 83.2% identity (90.5% similar) in 315 aa overlap (1-312:634-947)
10 20 30
pF1KE2 MLPEDKEADSLRGNISVKAVKKEVEKKLRC
.:: : . :: . .. : :::: :.. :
XP_016 VQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQRTRH
610 620 630 640 650 660
40 50 60 70 80
pF1KE2 LLADLPLPPELPGGDDLSK--SPEEKK-TATQLHSKRRPKICGPRYGETKEKDIDWGKRC
::.:::::::::::: :: ::: : : : :.::::: ::::: .. . ::::::
XP_016 LLTDLPLPPELPGGD-LSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWGKRC
670 680 690 700 710 720
90 100 110 120 130 140
pF1KE2 VDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTH
:::::::::::::::::::::.::::::.::::::::::::::::::::::::::::: :
XP_016 VDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIH
730 740 750 760 770 780
150 160 170 180 190 200
pF1KE2 QSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQL
.:..:::::::::.::::::::::::::::::::::::::::::::::.:.::::::.::
XP_016 RSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQL
790 800 810 820 830 840
210 220 230 240 250 260
pF1KE2 MEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRP
::::.::::::::::::::::::::: ::::::::::::::.::::::::::::::::::
XP_016 MEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRP
850 860 870 880 890 900
270 280 290 300 310 320
pF1KE2 PELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELIRHEENEVSDKQI
:::::::::::::::::::::::::::::::::::: ::::::::
XP_016 PELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDV
910 920 930 940 950 960
XP_016 IKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDV
970 980 990 1000 1010 1020
>>XP_016880239 (OMIM: 615514) cyclin-dependent kinase 12 (1262 aa)
initn: 1673 init1: 1577 opt: 1746 Z-score: 642.6 bits: 129.1 E(91609): 5e-29
Smith-Waterman score: 1746; 83.2% identity (90.5% similar) in 315 aa overlap (1-312:635-948)
10 20 30
pF1KE2 MLPEDKEADSLRGNISVKAVKKEVEKKLRC
.:: : . :: . .. : :::: :.. :
XP_016 VQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQRTRH
610 620 630 640 650 660
40 50 60 70 80
pF1KE2 LLADLPLPPELPGGDDLSK--SPEEKK-TATQLHSKRRPKICGPRYGETKEKDIDWGKRC
::.:::::::::::: :: ::: : : : :.::::: ::::: .. . ::::::
XP_016 LLTDLPLPPELPGGD-LSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWGKRC
670 680 690 700 710 720
90 100 110 120 130 140
pF1KE2 VDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTH
:::::::::::::::::::::.::::::.::::::::::::::::::::::::::::: :
XP_016 VDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIH
730 740 750 760 770 780
150 160 170 180 190 200
pF1KE2 QSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQL
.:..:::::::::.::::::::::::::::::::::::::::::::::.:.::::::.::
XP_016 RSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQL
790 800 810 820 830 840
210 220 230 240 250 260
pF1KE2 MEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRP
::::.::::::::::::::::::::: ::::::::::::::.::::::::::::::::::
XP_016 MEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRP
850 860 870 880 890 900
270 280 290 300 310 320
pF1KE2 PELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELIRHEENEVSDKQI
:::::::::::::::::::::::::::::::::::: ::::::::
XP_016 PELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDV
910 920 930 940 950 960
XP_016 IKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDV
970 980 990 1000 1010 1020
>>XP_011523209 (OMIM: 615514) cyclin-dependent kinase 12 (1262 aa)
initn: 1673 init1: 1577 opt: 1746 Z-score: 642.6 bits: 129.1 E(91609): 5e-29
Smith-Waterman score: 1746; 83.2% identity (90.5% similar) in 315 aa overlap (1-312:635-948)
10 20 30
pF1KE2 MLPEDKEADSLRGNISVKAVKKEVEKKLRC
.:: : . :: . .. : :::: :.. :
XP_011 VQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQRTRH
610 620 630 640 650 660
40 50 60 70 80
pF1KE2 LLADLPLPPELPGGDDLSK--SPEEKK-TATQLHSKRRPKICGPRYGETKEKDIDWGKRC
::.:::::::::::: :: ::: : : : :.::::: ::::: .. . ::::::
XP_011 LLTDLPLPPELPGGD-LSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWGKRC
670 680 690 700 710 720
90 100 110 120 130 140
pF1KE2 VDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTH
:::::::::::::::::::::.::::::.::::::::::::::::::::::::::::: :
XP_011 VDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIH
730 740 750 760 770 780
150 160 170 180 190 200
pF1KE2 QSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQL
.:..:::::::::.::::::::::::::::::::::::::::::::::.:.::::::.::
XP_011 RSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQL
790 800 810 820 830 840
210 220 230 240 250 260
pF1KE2 MEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRP
::::.::::::::::::::::::::: ::::::::::::::.::::::::::::::::::
XP_011 MEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRP
850 860 870 880 890 900
270 280 290 300 310 320
pF1KE2 PELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELIRHEENEVSDKQI
:::::::::::::::::::::::::::::::::::: ::::::::
XP_011 PELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDV
910 920 930 940 950 960
XP_011 IKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDV
970 980 990 1000 1010 1020
>>XP_016880240 (OMIM: 615514) cyclin-dependent kinase 12 (1262 aa)
initn: 1673 init1: 1577 opt: 1746 Z-score: 642.6 bits: 129.1 E(91609): 5e-29
Smith-Waterman score: 1746; 83.2% identity (90.5% similar) in 315 aa overlap (1-312:635-948)
10 20 30
pF1KE2 MLPEDKEADSLRGNISVKAVKKEVEKKLRC
.:: : . :: . .. : :::: :.. :
XP_016 VQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQRTRH
610 620 630 640 650 660
40 50 60 70 80
pF1KE2 LLADLPLPPELPGGDDLSK--SPEEKK-TATQLHSKRRPKICGPRYGETKEKDIDWGKRC
::.:::::::::::: :: ::: : : : :.::::: ::::: .. . ::::::
XP_016 LLTDLPLPPELPGGD-LSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWGKRC
670 680 690 700 710 720
90 100 110 120 130 140
pF1KE2 VDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTH
:::::::::::::::::::::.::::::.::::::::::::::::::::::::::::: :
XP_016 VDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIH
730 740 750 760 770 780
150 160 170 180 190 200
pF1KE2 QSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQL
.:..:::::::::.::::::::::::::::::::::::::::::::::.:.::::::.::
XP_016 RSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQL
790 800 810 820 830 840
210 220 230 240 250 260
pF1KE2 MEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRP
::::.::::::::::::::::::::: ::::::::::::::.::::::::::::::::::
XP_016 MEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRP
850 860 870 880 890 900
270 280 290 300 310 320
pF1KE2 PELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELIRHEENEVSDKQI
:::::::::::::::::::::::::::::::::::: ::::::::
XP_016 PELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDV
910 920 930 940 950 960
XP_016 IKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDV
970 980 990 1000 1010 1020
>>XP_016880241 (OMIM: 615514) cyclin-dependent kinase 12 (1262 aa)
initn: 1673 init1: 1577 opt: 1746 Z-score: 642.6 bits: 129.1 E(91609): 5e-29
Smith-Waterman score: 1746; 83.2% identity (90.5% similar) in 315 aa overlap (1-312:635-948)
10 20 30
pF1KE2 MLPEDKEADSLRGNISVKAVKKEVEKKLRC
.:: : . :: . .. : :::: :.. :
XP_016 VQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQRTRH
610 620 630 640 650 660
40 50 60 70 80
pF1KE2 LLADLPLPPELPGGDDLSK--SPEEKK-TATQLHSKRRPKICGPRYGETKEKDIDWGKRC
::.:::::::::::: :: ::: : : : :.::::: ::::: .. . ::::::
XP_016 LLTDLPLPPELPGGD-LSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWGKRC
670 680 690 700 710 720
90 100 110 120 130 140
pF1KE2 VDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTH
:::::::::::::::::::::.::::::.::::::::::::::::::::::::::::: :
XP_016 VDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIH
730 740 750 760 770 780
150 160 170 180 190 200
pF1KE2 QSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQL
.:..:::::::::.::::::::::::::::::::::::::::::::::.:.::::::.::
XP_016 RSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQL
790 800 810 820 830 840
210 220 230 240 250 260
pF1KE2 MEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRP
::::.::::::::::::::::::::: ::::::::::::::.::::::::::::::::::
XP_016 MEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRP
850 860 870 880 890 900
270 280 290 300 310 320
pF1KE2 PELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELIRHEENEVSDKQI
:::::::::::::::::::::::::::::::::::: ::::::::
XP_016 PELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDV
910 920 930 940 950 960
XP_016 IKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDV
970 980 990 1000 1010 1020
>>XP_011523198 (OMIM: 615514) cyclin-dependent kinase 12 (1393 aa)
initn: 1673 init1: 1577 opt: 1746 Z-score: 642.2 bits: 129.2 E(91609): 5.3e-29
Smith-Waterman score: 1746; 83.2% identity (90.5% similar) in 315 aa overlap (1-312:635-948)
10 20 30
pF1KE2 MLPEDKEADSLRGNISVKAVKKEVEKKLRC
.:: : . :: . .. : :::: :.. :
XP_011 VQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQRTRH
610 620 630 640 650 660
40 50 60 70 80
pF1KE2 LLADLPLPPELPGGDDLSK--SPEEKK-TATQLHSKRRPKICGPRYGETKEKDIDWGKRC
::.:::::::::::: :: ::: : : : :.::::: ::::: .. . ::::::
XP_011 LLTDLPLPPELPGGD-LSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWGKRC
670 680 690 700 710 720
90 100 110 120 130 140
pF1KE2 VDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTH
:::::::::::::::::::::.::::::.::::::::::::::::::::::::::::: :
XP_011 VDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIH
730 740 750 760 770 780
150 160 170 180 190 200
pF1KE2 QSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQL
.:..:::::::::.::::::::::::::::::::::::::::::::::.:.::::::.::
XP_011 RSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQL
790 800 810 820 830 840
210 220 230 240 250 260
pF1KE2 MEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRP
::::.::::::::::::::::::::: ::::::::::::::.::::::::::::::::::
XP_011 MEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRP
850 860 870 880 890 900
270 280 290 300 310 320
pF1KE2 PELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELIRHEENEVSDKQI
:::::::::::::::::::::::::::::::::::: ::::::::
XP_011 PELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDV
910 920 930 940 950 960
XP_011 IKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDV
970 980 990 1000 1010 1020
>>XP_024306569 (OMIM: 615514) cyclin-dependent kinase 12 (1393 aa)
initn: 1673 init1: 1577 opt: 1746 Z-score: 642.2 bits: 129.2 E(91609): 5.3e-29
Smith-Waterman score: 1746; 83.2% identity (90.5% similar) in 315 aa overlap (1-312:635-948)
10 20 30
pF1KE2 MLPEDKEADSLRGNISVKAVKKEVEKKLRC
.:: : . :: . .. : :::: :.. :
XP_024 VQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQRTRH
610 620 630 640 650 660
40 50 60 70 80
pF1KE2 LLADLPLPPELPGGDDLSK--SPEEKK-TATQLHSKRRPKICGPRYGETKEKDIDWGKRC
::.:::::::::::: :: ::: : : : :.::::: ::::: .. . ::::::
XP_024 LLTDLPLPPELPGGD-LSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWGKRC
670 680 690 700 710 720
90 100 110 120 130 140
pF1KE2 VDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTH
:::::::::::::::::::::.::::::.::::::::::::::::::::::::::::: :
XP_024 VDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIH
730 740 750 760 770 780
150 160 170 180 190 200
pF1KE2 QSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQL
.:..:::::::::.::::::::::::::::::::::::::::::::::.:.::::::.::
XP_024 RSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQL
790 800 810 820 830 840
210 220 230 240 250 260
pF1KE2 MEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRP
::::.::::::::::::::::::::: ::::::::::::::.::::::::::::::::::
XP_024 MEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRP
850 860 870 880 890 900
270 280 290 300 310 320
pF1KE2 PELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELIRHEENEVSDKQI
:::::::::::::::::::::::::::::::::::: ::::::::
XP_024 PELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDV
910 920 930 940 950 960
XP_024 IKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDV
970 980 990 1000 1010 1020
324 residues in 1 query sequences
64848753 residues in 91609 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Aug 17 17:45:49 2018 done: Fri Aug 17 17:45:50 2018
Total Scan time: 6.330 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]