Result of FASTA (omim) for
pFN21AE2707
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2707, 237 aa
1>>>pF1KE2707 237 - 237 aa - 237 aa
Library: /omim/omim.rfq.tfa
63717318 residues in 89588 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.1244+/-0.00031; mu= 11.2697+/- 0.019
mean_var=95.3041+/-18.710, 0's: 0 Z-trim(118.3): 11 B-trim: 33 in 1/51
Lambda= 0.131377
statistics sampled from 31807 (31817) to 31807 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.723), E-opt: 0.2 (0.355), width: 16
Scan time: 3.240
The best scores are: opt bits E(89588)
NP_919415 (OMIM: 605703) vesicle-associated membra ( 249) 1590 311.0 1.3e-84
XP_016881568 (OMIM: 605703) PREDICTED: vesicle-ass ( 236) 1455 285.4 6.1e-77
NP_004729 (OMIM: 182980,605704,608627) vesicle-ass ( 243) 1001 199.4 5e-51
NP_003565 (OMIM: 605703) vesicle-associated membra ( 294) 918 183.7 3.2e-46
XP_011524071 (OMIM: 605703) PREDICTED: vesicle-ass ( 281) 783 158.1 1.5e-38
NP_001182606 (OMIM: 182980,605704,608627) vesicle- ( 99) 376 80.6 1.1e-15
>>NP_919415 (OMIM: 605703) vesicle-associated membrane p (249 aa)
initn: 1590 init1: 1590 opt: 1590 Z-score: 1640.6 bits: 311.0 E(89588): 1.3e-84
Smith-Waterman score: 1590; 100.0% identity (100.0% similar) in 237 aa overlap (1-237:8-244)
10 20 30 40 50
pF1KE2 MAKHEQILVLDPPTDLKFKGPFTDVVTTNLKLRNPSDRKVCFKVKTTAPRRYC
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_919 MASASGAMAKHEQILVLDPPTDLKFKGPFTDVVTTNLKLRNPSDRKVCFKVKTTAPRRYC
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 VRPNSGIIDPGSTVTVSVMLQPFDYDPNEKSKHKFMVQTIFAPPNTSDMEAVWKEAKPDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_919 VRPNSGIIDPGSTVTVSVMLQPFDYDPNEKSKHKFMVQTIFAPPNTSDMEAVWKEAKPDE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 LMDSKLRCVFEMPNENDKLNDMEPSKAVPLNASKQDGPMPKPHSVSLNDTETRKLMEECK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_919 LMDSKLRCVFEMPNENDKLNDMEPSKAVPLNASKQDGPMPKPHSVSLNDTETRKLMEECK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE2 RLQGEMMKLSEENRHLRDEGLRLRKVAHSDKPGSTSTASFRDNVTSPLPSLLVVIAAIFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_919 RLQGEMMKLSEENRHLRDEGLRLRKVAHSDKPGSTSTASFRDNVTSPLPSLLVVIAAIFI
190 200 210 220 230 240
pF1KE2 GFFL
::::
NP_919 GFFLGKFIL
>>XP_016881568 (OMIM: 605703) PREDICTED: vesicle-associa (236 aa)
initn: 1455 init1: 1455 opt: 1455 Z-score: 1502.7 bits: 285.4 E(89588): 6.1e-77
Smith-Waterman score: 1455; 100.0% identity (100.0% similar) in 217 aa overlap (21-237:15-231)
10 20 30 40 50 60
pF1KE2 MAKHEQILVLDPPTDLKFKGPFTDVVTTNLKLRNPSDRKVCFKVKTTAPRRYCVRPNSGI
::::::::::::::::::::::::::::::::::::::::
XP_016 MLQSKYSKMFIVECPFTDVVTTNLKLRNPSDRKVCFKVKTTAPRRYCVRPNSGI
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 IDPGSTVTVSVMLQPFDYDPNEKSKHKFMVQTIFAPPNTSDMEAVWKEAKPDELMDSKLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDPGSTVTVSVMLQPFDYDPNEKSKHKFMVQTIFAPPNTSDMEAVWKEAKPDELMDSKLR
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE2 CVFEMPNENDKLNDMEPSKAVPLNASKQDGPMPKPHSVSLNDTETRKLMEECKRLQGEMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CVFEMPNENDKLNDMEPSKAVPLNASKQDGPMPKPHSVSLNDTETRKLMEECKRLQGEMM
120 130 140 150 160 170
190 200 210 220 230
pF1KE2 KLSEENRHLRDEGLRLRKVAHSDKPGSTSTASFRDNVTSPLPSLLVVIAAIFIGFFL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLSEENRHLRDEGLRLRKVAHSDKPGSTSTASFRDNVTSPLPSLLVVIAAIFIGFFLGKF
180 190 200 210 220 230
XP_016 IL
>>NP_004729 (OMIM: 182980,605704,608627) vesicle-associa (243 aa)
initn: 985 init1: 800 opt: 1001 Z-score: 1037.4 bits: 199.4 E(89588): 5e-51
Smith-Waterman score: 1001; 63.2% identity (87.0% similar) in 239 aa overlap (1-234:1-239)
10 20 30 40 50 60
pF1KE2 MAKHEQILVLDPPTDLKFKGPFTDVVTTNLKLRNPSDRKVCFKVKTTAPRRYCVRPNSGI
::: ::.: :.: .:::.::::::::::::: ::.::.:::::::::::::::::::::
NP_004 MAKVEQVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 IDPGSTVTVSVMLQPFDYDPNEKSKHKFMVQTIFAPPNTSDMEAVWKEAKPDELMDSKLR
:: :....:::::::::::::::::::::::..::: .:::::::::::::..:::::::
NP_004 IDAGASINVSVMLQPFDYDPNEKSKHKFMVQSMFAPTDTSDMEAVWKEAKPEDLMDSKLR
70 80 90 100 110 120
130 140 150 160 170
pF1KE2 CVFEMPNENDKLNDMEPSKAVPLNASKQDGPM-PKPHSVSLNDTETRKLMEECKRLQGEM
::::.: :::: .:.: .: . .::: . :. : : ::.:::..:.::::::::::.
NP_004 CVFELPAENDKPHDVEINKIISTTASKTETPIVSKSLSSSLDDTEVKKVMEECKRLQGEV
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE2 MKLSEENRHLRDE-GLRLRKVAHSDKPGSTSTASFRDN-VTSPLPSLLVV--IAAIFIGF
..: :::.....: :::.::...:..: :. . . ... ... : .:.:. :....::
NP_004 QRLREENKQFKEEDGLRMRKTVQSNSPISALAPTGKEEGLSTRLLALVVLFFIVGVIIGK
190 200 210 220 230 240
pF1KE2 FL
NP_004 IAL
>>NP_003565 (OMIM: 605703) vesicle-associated membrane p (294 aa)
initn: 912 init1: 912 opt: 918 Z-score: 951.2 bits: 183.7 E(89588): 3.2e-46
Smith-Waterman score: 1413; 83.3% identity (83.3% similar) in 269 aa overlap (1-224:8-276)
10 20 30 40 50
pF1KE2 MAKHEQILVLDPPTDLKFKGPFTDVVTTNLKLRNPSDRKVCFKVKTTAPRRYC
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MASASGAMAKHEQILVLDPPTDLKFKGPFTDVVTTNLKLRNPSDRKVCFKVKTTAPRRYC
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 VRPNSGIIDPGSTVTVSVMLQPFDYDPNEKSKHKFMVQTIFAPPNTSDMEAVWKEAKPDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VRPNSGIIDPGSTVTVSVMLQPFDYDPNEKSKHKFMVQTIFAPPNTSDMEAVWKEAKPDE
70 80 90 100 110 120
120 130
pF1KE2 LMDSKLRCVFEMPNENDKL-----------------------------------------
:::::::::::::::::::
NP_003 LMDSKLRCVFEMPNENDKLGITPPGNAPTVTSMSSINNTVATPASYHTKDDPRGLSVLKQ
130 140 150 160 170 180
140 150 160 170 180
pF1KE2 ----NDMEPSKAVPLNASKQDGPMPKPHSVSLNDTETRKLMEECKRLQGEMMKLSEENRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EKQKNDMEPSKAVPLNASKQDGPMPKPHSVSLNDTETRKLMEECKRLQGEMMKLSEENRH
190 200 210 220 230 240
190 200 210 220 230
pF1KE2 LRDEGLRLRKVAHSDKPGSTSTASFRDNVTSPLPSLLVVIAAIFIGFFL
::::::::::::::::::::::::::::::::::::
NP_003 LRDEGLRLRKVAHSDKPGSTSTASFRDNVTSPLPSLLVVIAAIFIGFFLGKFIL
250 260 270 280 290
>>XP_011524071 (OMIM: 605703) PREDICTED: vesicle-associa (281 aa)
initn: 777 init1: 777 opt: 783 Z-score: 813.2 bits: 158.1 E(89588): 1.5e-38
Smith-Waterman score: 1278; 81.9% identity (81.9% similar) in 249 aa overlap (21-224:15-263)
10 20 30 40 50 60
pF1KE2 MAKHEQILVLDPPTDLKFKGPFTDVVTTNLKLRNPSDRKVCFKVKTTAPRRYCVRPNSGI
::::::::::::::::::::::::::::::::::::::::
XP_011 MLQSKYSKMFIVECPFTDVVTTNLKLRNPSDRKVCFKVKTTAPRRYCVRPNSGI
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 IDPGSTVTVSVMLQPFDYDPNEKSKHKFMVQTIFAPPNTSDMEAVWKEAKPDELMDSKLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDPGSTVTVSVMLQPFDYDPNEKSKHKFMVQTIFAPPNTSDMEAVWKEAKPDELMDSKLR
60 70 80 90 100 110
130
pF1KE2 CVFEMPNENDKL---------------------------------------------NDM
:::::::::::: :::
XP_011 CVFEMPNENDKLGITPPGNAPTVTSMSSINNTVATPASYHTKDDPRGLSVLKQEKQKNDM
120 130 140 150 160 170
140 150 160 170 180 190
pF1KE2 EPSKAVPLNASKQDGPMPKPHSVSLNDTETRKLMEECKRLQGEMMKLSEENRHLRDEGLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPSKAVPLNASKQDGPMPKPHSVSLNDTETRKLMEECKRLQGEMMKLSEENRHLRDEGLR
180 190 200 210 220 230
200 210 220 230
pF1KE2 LRKVAHSDKPGSTSTASFRDNVTSPLPSLLVVIAAIFIGFFL
:::::::::::::::::::::::::::::
XP_011 LRKVAHSDKPGSTSTASFRDNVTSPLPSLLVVIAAIFIGFFLGKFIL
240 250 260 270 280
>>NP_001182606 (OMIM: 182980,605704,608627) vesicle-asso (99 aa)
initn: 392 init1: 372 opt: 376 Z-score: 402.9 bits: 80.6 E(89588): 1.1e-15
Smith-Waterman score: 376; 62.2% identity (81.1% similar) in 90 aa overlap (1-90:1-90)
10 20 30 40 50 60
pF1KE2 MAKHEQILVLDPPTDLKFKGPFTDVVTTNLKLRNPSDRKVCFKVKTTAPRRYCVRPNSGI
::: ::.: :.: .:::.::::::::::::: ::.::.:::::::::::::::::::::
NP_001 MAKVEQVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 IDPGSTVTVSVMLQPFDYDPNEKSKHKFMVQTIFAPPNTSDMEAVWKEAKPDELMDSKLR
:: :....:: : . . ... .: .
NP_001 IDAGASINVSGRRWTADEEDSAEQQPHFSISPNWEGRRP
70 80 90
237 residues in 1 query sequences
63717318 residues in 89588 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Dec 15 09:59:30 2017 done: Fri Dec 15 09:59:31 2017
Total Scan time: 3.240 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]