Result of FASTA (omim) for
pFN21AE2687
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2687, 579 aa
1>>>pF1KE2687 579 - 579 aa - 579 aa
Library: /omim/omim.rfq.tfa
61989856 residues in 87180 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5607+/-0.00036; mu= 18.7307+/- 0.022
mean_var=95.9959+/-19.190, 0's: 0 Z-trim(115.5): 18 B-trim: 49 in 2/53
Lambda= 0.130902
statistics sampled from 26248 (26264) to 26248 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.669), E-opt: 0.2 (0.301), width: 16
Scan time: 9.860
The best scores are: opt bits E(87180)
NP_001432 (OMIM: 602935,606581) fatty-acid amide h ( 579) 3898 746.8 4.4e-215
XP_005262044 (OMIM: 300654) PREDICTED: fatty-acid ( 341) 383 82.8 2e-15
XP_005262043 (OMIM: 300654) PREDICTED: fatty-acid ( 346) 383 82.8 2e-15
XP_016884783 (OMIM: 300654) PREDICTED: fatty-acid ( 349) 383 82.8 2e-15
XP_016884782 (OMIM: 300654) PREDICTED: fatty-acid ( 361) 383 82.8 2.1e-15
XP_011529069 (OMIM: 300654) PREDICTED: fatty-acid ( 449) 383 82.9 2.5e-15
XP_005262042 (OMIM: 300654) PREDICTED: fatty-acid ( 449) 383 82.9 2.5e-15
XP_016884779 (OMIM: 300654) PREDICTED: fatty-acid ( 487) 383 83.0 2.6e-15
XP_005262039 (OMIM: 300654) PREDICTED: fatty-acid ( 492) 383 83.0 2.6e-15
NP_777572 (OMIM: 300654) fatty-acid amide hydrolas ( 532) 383 83.0 2.8e-15
XP_016884781 (OMIM: 300654) PREDICTED: fatty-acid ( 417) 199 48.2 6.7e-05
XP_016884780 (OMIM: 300654) PREDICTED: fatty-acid ( 462) 199 48.2 7.2e-05
XP_011534226 (OMIM: 617209) PREDICTED: glutamyl-tR ( 437) 178 44.2 0.0011
NP_060762 (OMIM: 617209) glutamyl-tRNA(Gln) amidot ( 528) 178 44.3 0.0012
>>NP_001432 (OMIM: 602935,606581) fatty-acid amide hydro (579 aa)
initn: 3898 init1: 3898 opt: 3898 Z-score: 3982.6 bits: 746.8 E(87180): 4.4e-215
Smith-Waterman score: 3898; 99.8% identity (99.8% similar) in 579 aa overlap (1-579:1-579)
10 20 30 40 50 60
pF1KE2 MVQYELWAALPGASGVALACCFVAAAVALRWSGRRTARGAVVRARQRQRAGLENMDRAAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVQYELWAALPGASGVALACCFVAAAVALRWSGRRTARGAVVRARQRQRAGLENMDRAAQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 RFRLQNPDLDSEALLALPLPQLVQKLHSRELAPEAVLFTYVGKAWEVNKGTNCVTSYLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFRLQNPDLDSEALLALPLPQLVQKLHSRELAPEAVLFTYVGKAWEVNKGTNCVTSYLAD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 CETQLSQATRQGLLYGVPVSLKECFTYKGQDSTLGLSLNEGVPAECDSVVVHVLKLQGAV
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CETQLSQAPRQGLLYGVPVSLKECFTYKGQDSTLGLSLNEGVPAECDSVVVHVLKLQGAV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 PFVHTNVPQSMFSYDCSNPLFGQTVNPWKSSKSPGGSSGGEGALIGSGGSPLGLGTDIGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PFVHTNVPQSMFSYDCSNPLFGQTVNPWKSSKSPGGSSGGEGALIGSGGSPLGLGTDIGG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SIRFPSSFCGICGLKPTGNRLSKSGLKGCVYGQEAVRLSVGPMARDVESLALCLRALLCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SIRFPSSFCGICGLKPTGNRLSKSGLKGCVYGQEAVRLSVGPMARDVESLALCLRALLCE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 DMFRLDPTVPPLPFREEVYTSSQPLRVGYYETDNYTMPSPAMRRAVLETKQSLEAAGHTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DMFRLDPTVPPLPFREEVYTSSQPLRVGYYETDNYTMPSPAMRRAVLETKQSLEAAGHTL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 VPFLPSNIPHALETLSTGGLFSDGGHTFLQNFKGDFVDPCLGDLVSILKLPQWLKGLLAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPFLPSNIPHALETLSTGGLFSDGGHTFLQNFKGDFVDPCLGDLVSILKLPQWLKGLLAF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 LVKPLLPRLSAFLSNMKSRSAGKLWELQHEIEVYRKTVIAQWRALDLDVVLTPMLAPALD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVKPLLPRLSAFLSNMKSRSAGKLWELQHEIEVYRKTVIAQWRALDLDVVLTPMLAPALD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 LNAPGRATGAVSYTMLYNCLDFPAGVVPVTTVTAEDEAQMEHYRGYFGDIWDKMLQKGMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNAPGRATGAVSYTMLYNCLDFPAGVVPVTTVTAEDEAQMEHYRGYFGDIWDKMLQKGMK
490 500 510 520 530 540
550 560 570
pF1KE2 KSVGLPVAVQCVALPWQEELCLRFMREVERLMTPEKQSS
:::::::::::::::::::::::::::::::::::::::
NP_001 KSVGLPVAVQCVALPWQEELCLRFMREVERLMTPEKQSS
550 560 570
>>XP_005262044 (OMIM: 300654) PREDICTED: fatty-acid amid (341 aa)
initn: 375 init1: 375 opt: 383 Z-score: 398.0 bits: 82.8 E(87180): 2e-15
Smith-Waterman score: 409; 31.5% identity (60.4% similar) in 260 aa overlap (61-305:35-294)
40 50 60 70 80 90
pF1KE2 WSGRRTARGAVVRARQRQRAGLENMDRAAQRFRLQNPDLDSEALLALPLPQLVQKLHSRE
.: ..: .: :: : ::.. ...:.
XP_005 FTARIQLFLLRALGFLIGLVGRAALVLGGPKFASKTPRPVTEPLLLLSGMQLAKLIRQRK
10 20 30 40 50 60
100 110 120 130
pF1KE2 LAPEAVLFTYVGKAWEVNKGTNCVTSYLADCETQLSQATRQGL---------------LY
. :. .:... .:: : ...: . . ..:. : : .
XP_005 VKCIDVVQAYINRIKDVNPMINGIVKYRFEEAMKEAHAVDQKLAEKQEDEATLENKWPFL
70 80 90 100 110 120
140 150 160 170 180 190
pF1KE2 GVPVSLKECFTYKGQDSTLGLSLNEGVPAECDSVVVHVLKLQGAVPFVHTNVPQSMFSYD
:::...:: : .:. .. :: . . :. :..:: .:: ::.:. :: . . :.
XP_005 GVPLTVKEAFQLQGMPNSSGLMNRRDAIAKTDATVVALLKGAGAIPLGITNCSELCMWYE
130 140 150 160 170 180
200 210 220 230 240 250
pF1KE2 CSNPLFGQTVNPWKSSKSPGGSSGGEGALIGSGGSPLGLGTDIGGSIRFPSSFCGICGLK
:: ..:.. ::. .. :::::::: .... : .:.:.:::::::.:. : :: : :
XP_005 SSNKIYGRSNNPYDLQHIVGGSSGGEGCTLAAACSVIGVGSDIGGSIRMPAFFNGIFGHK
190 200 210 220 230 240
260 270 280 290 300 310
pF1KE2 PTGNRLSKSGLKGCVYGQEAVRLSVGPMARDVESLALCLRALLCEDMFRLDPTVPPLPFR
:. . . ..: . : . . : .::: : .:.:: :... . ::
XP_005 PSPGVVPNKGQFPLAVGAQELFLCTGPMCRYAEDLAPMLKVMAGPGIKRLKLDTKVHLKD
250 260 270 280 290 300
320 330 340 350 360 370
pF1KE2 EEVYTSSQPLRVGYYETDNYTMPSPAMRRAVLETKQSLEAAGHTLVPFLPSNIPHALETL
XP_005 LKFYWMEHDGGSFLMSKVDQDLIMTQKKVSSVPWVCL
310 320 330 340
>>XP_005262043 (OMIM: 300654) PREDICTED: fatty-acid amid (346 aa)
initn: 375 init1: 375 opt: 383 Z-score: 398.0 bits: 82.8 E(87180): 2e-15
Smith-Waterman score: 409; 31.5% identity (60.4% similar) in 260 aa overlap (61-305:35-294)
40 50 60 70 80 90
pF1KE2 WSGRRTARGAVVRARQRQRAGLENMDRAAQRFRLQNPDLDSEALLALPLPQLVQKLHSRE
.: ..: .: :: : ::.. ...:.
XP_005 FTARIQLFLLRALGFLIGLVGRAALVLGGPKFASKTPRPVTEPLLLLSGMQLAKLIRQRK
10 20 30 40 50 60
100 110 120 130
pF1KE2 LAPEAVLFTYVGKAWEVNKGTNCVTSYLADCETQLSQATRQGL---------------LY
. :. .:... .:: : ...: . . ..:. : : .
XP_005 VKCIDVVQAYINRIKDVNPMINGIVKYRFEEAMKEAHAVDQKLAEKQEDEATLENKWPFL
70 80 90 100 110 120
140 150 160 170 180 190
pF1KE2 GVPVSLKECFTYKGQDSTLGLSLNEGVPAECDSVVVHVLKLQGAVPFVHTNVPQSMFSYD
:::...:: : .:. .. :: . . :. :..:: .:: ::.:. :: . . :.
XP_005 GVPLTVKEAFQLQGMPNSSGLMNRRDAIAKTDATVVALLKGAGAIPLGITNCSELCMWYE
130 140 150 160 170 180
200 210 220 230 240 250
pF1KE2 CSNPLFGQTVNPWKSSKSPGGSSGGEGALIGSGGSPLGLGTDIGGSIRFPSSFCGICGLK
:: ..:.. ::. .. :::::::: .... : .:.:.:::::::.:. : :: : :
XP_005 SSNKIYGRSNNPYDLQHIVGGSSGGEGCTLAAACSVIGVGSDIGGSIRMPAFFNGIFGHK
190 200 210 220 230 240
260 270 280 290 300 310
pF1KE2 PTGNRLSKSGLKGCVYGQEAVRLSVGPMARDVESLALCLRALLCEDMFRLDPTVPPLPFR
:. . . ..: . : . . : .::: : .:.:: :... . ::
XP_005 PSPGVVPNKGQFPLAVGAQELFLCTGPMCRYAEDLAPMLKVMAGPGIKRLKLDTKVHLKD
250 260 270 280 290 300
320 330 340 350 360 370
pF1KE2 EEVYTSSQPLRVGYYETDNYTMPSPAMRRAVLETKQSLEAAGHTLVPFLPSNIPHALETL
XP_005 LKFYWMEHDGGSFLMSKVDQDLIMTQKKLITWKQWKTKKALT
310 320 330 340
>>XP_016884783 (OMIM: 300654) PREDICTED: fatty-acid amid (349 aa)
initn: 375 init1: 375 opt: 383 Z-score: 397.9 bits: 82.8 E(87180): 2e-15
Smith-Waterman score: 409; 31.5% identity (60.4% similar) in 260 aa overlap (61-305:35-294)
40 50 60 70 80 90
pF1KE2 WSGRRTARGAVVRARQRQRAGLENMDRAAQRFRLQNPDLDSEALLALPLPQLVQKLHSRE
.: ..: .: :: : ::.. ...:.
XP_016 FTARIQLFLLRALGFLIGLVGRAALVLGGPKFASKTPRPVTEPLLLLSGMQLAKLIRQRK
10 20 30 40 50 60
100 110 120 130
pF1KE2 LAPEAVLFTYVGKAWEVNKGTNCVTSYLADCETQLSQATRQGL---------------LY
. :. .:... .:: : ...: . . ..:. : : .
XP_016 VKCIDVVQAYINRIKDVNPMINGIVKYRFEEAMKEAHAVDQKLAEKQEDEATLENKWPFL
70 80 90 100 110 120
140 150 160 170 180 190
pF1KE2 GVPVSLKECFTYKGQDSTLGLSLNEGVPAECDSVVVHVLKLQGAVPFVHTNVPQSMFSYD
:::...:: : .:. .. :: . . :. :..:: .:: ::.:. :: . . :.
XP_016 GVPLTVKEAFQLQGMPNSSGLMNRRDAIAKTDATVVALLKGAGAIPLGITNCSELCMWYE
130 140 150 160 170 180
200 210 220 230 240 250
pF1KE2 CSNPLFGQTVNPWKSSKSPGGSSGGEGALIGSGGSPLGLGTDIGGSIRFPSSFCGICGLK
:: ..:.. ::. .. :::::::: .... : .:.:.:::::::.:. : :: : :
XP_016 SSNKIYGRSNNPYDLQHIVGGSSGGEGCTLAAACSVIGVGSDIGGSIRMPAFFNGIFGHK
190 200 210 220 230 240
260 270 280 290 300 310
pF1KE2 PTGNRLSKSGLKGCVYGQEAVRLSVGPMARDVESLALCLRALLCEDMFRLDPTVPPLPFR
:. . . ..: . : . . : .::: : .:.:: :... . ::
XP_016 PSPGVVPNKGQFPLAVGAQELFLCTGPMCRYAEDLAPMLKVMAGPGIKRLKLDTKVHLKD
250 260 270 280 290 300
320 330 340 350 360 370
pF1KE2 EEVYTSSQPLRVGYYETDNYTMPSPAMRRAVLETKQSLEAAGHTLVPFLPSNIPHALETL
XP_016 LKFYWMEHDGGSFLMSKVDQDLIMTQKKIFCAMILILSSTGSLRS
310 320 330 340
>>XP_016884782 (OMIM: 300654) PREDICTED: fatty-acid amid (361 aa)
initn: 375 init1: 375 opt: 383 Z-score: 397.7 bits: 82.8 E(87180): 2.1e-15
Smith-Waterman score: 409; 31.5% identity (60.4% similar) in 260 aa overlap (61-305:35-294)
40 50 60 70 80 90
pF1KE2 WSGRRTARGAVVRARQRQRAGLENMDRAAQRFRLQNPDLDSEALLALPLPQLVQKLHSRE
.: ..: .: :: : ::.. ...:.
XP_016 FTARIQLFLLRALGFLIGLVGRAALVLGGPKFASKTPRPVTEPLLLLSGMQLAKLIRQRK
10 20 30 40 50 60
100 110 120 130
pF1KE2 LAPEAVLFTYVGKAWEVNKGTNCVTSYLADCETQLSQATRQGL---------------LY
. :. .:... .:: : ...: . . ..:. : : .
XP_016 VKCIDVVQAYINRIKDVNPMINGIVKYRFEEAMKEAHAVDQKLAEKQEDEATLENKWPFL
70 80 90 100 110 120
140 150 160 170 180 190
pF1KE2 GVPVSLKECFTYKGQDSTLGLSLNEGVPAECDSVVVHVLKLQGAVPFVHTNVPQSMFSYD
:::...:: : .:. .. :: . . :. :..:: .:: ::.:. :: . . :.
XP_016 GVPLTVKEAFQLQGMPNSSGLMNRRDAIAKTDATVVALLKGAGAIPLGITNCSELCMWYE
130 140 150 160 170 180
200 210 220 230 240 250
pF1KE2 CSNPLFGQTVNPWKSSKSPGGSSGGEGALIGSGGSPLGLGTDIGGSIRFPSSFCGICGLK
:: ..:.. ::. .. :::::::: .... : .:.:.:::::::.:. : :: : :
XP_016 SSNKIYGRSNNPYDLQHIVGGSSGGEGCTLAAACSVIGVGSDIGGSIRMPAFFNGIFGHK
190 200 210 220 230 240
260 270 280 290 300 310
pF1KE2 PTGNRLSKSGLKGCVYGQEAVRLSVGPMARDVESLALCLRALLCEDMFRLDPTVPPLPFR
:. . . ..: . : . . : .::: : .:.:: :... . ::
XP_016 PSPGVVPNKGQFPLAVGAQELFLCTGPMCRYAEDLAPMLKVMAGPGIKRLKLDTKVHLKD
250 260 270 280 290 300
320 330 340 350 360 370
pF1KE2 EEVYTSSQPLRVGYYETDNYTMPSPAMRRAVLETKQSLEAAGHTLVPFLPSNIPHALETL
XP_016 LKFYWMEHDGGSFLMSKVDQDLIMTQKKIERVLVHVVKWIYCVMVKFGLLVYQSCKQ
310 320 330 340 350 360
>>XP_011529069 (OMIM: 300654) PREDICTED: fatty-acid amid (449 aa)
initn: 423 init1: 375 opt: 383 Z-score: 396.5 bits: 82.9 E(87180): 2.5e-15
Smith-Waterman score: 420; 27.6% identity (54.8% similar) in 456 aa overlap (106-544:12-441)
80 90 100 110 120 130
pF1KE2 ALPLPQLVQKLHSRELAPEAVLFTYVGKAWEVNKGTNCVTSYLADCETQLSQATRQGL--
:. : .. : . :: : : ..:: ..
XP_011 MINGIVKYRFEEAMKEAHAVDQKLA--EKQEDEATLENKWP
10 20 30
140 150 160 170 180 190
pF1KE2 LYGVPVSLKECFTYKGQDSTLGLSLNEGVPAECDSVVVHVLKLQGAVPFVHTNVPQSMFS
. :::...:: : .:. .. :: . . :. :..:: .:: ::.:. :: . .
XP_011 FLGVPLTVKEAFQLQGMPNSSGLMNRRDAIAKTDATVVALLKGAGAIPLGITNCSELCMW
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE2 YDCSNPLFGQTVNPWKSSKSPGGSSGGEGALIGSGGSPLGLGTDIGGSIRFPSSFCGICG
:. :: ..:.. ::. .. :::::::: .... : .:.:.:::::::.:. : :: :
XP_011 YESSNKIYGRSNNPYDLQHIVGGSSGGEGCTLAAACSVIGVGSDIGGSIRMPAFFNGIFG
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE2 LKPTGNRLSKSGLKGCVYGQEAVRLSVGPMARDVESLALCLRALLCEDMFRLDPTVPPLP
::. . . ..: . : . . : .::: : .:.:: :... : . :
XP_011 HKPSPGVVPNKGQFPLAVGAQELFLCTGPMCRYAEDLAPMLKVMA-------GPGIKRLK
160 170 180 190 200 210
320 330 340 350 360 370
pF1KE2 FREEVYTSSQPLRVGYYETDNYTMPSPAMRRAVLETKQSLEAAGHTLVPFLPSNIPHA-L
. .:. . :. ..: :. .. . . .. :.... . : : .: ... :. :
XP_011 LDTKVHL--KDLKFYWMEHDGGSFLMSKVDQDLIMTQKKVVV--H-LETILGASVQHVKL
220 230 240 250 260
380 390 400 410 420
pF1KE2 ETLSTG-----GLFSDGGHTFLQNFKGDFVDPCLGDL---VSIL-KLPQWLKGLLAFLVK
. .. . ...: :: . : ::: ::: :: : .: .: :: .. .
XP_011 KKMKYSFQLWIAMMSAKGHDGKEPVK--FVD-LLGDHGKHVSPLWELIKWCLGLSVYTI-
270 280 290 300 310 320
430 440 450 460 470
pF1KE2 PLLPRLSAFLSNMKSR-SAGKLWELQHEIEVYRKTVIAQWRALDLDVVLT----PMLAPA
: .. : . : : : : ... : :: .. . : : :. : .::
XP_011 ---PSIGLALLEEKLRYSNEKYQKFKAVEESLRKELVDM---LGDDGVFLYPSHPTVAPK
330 340 350 360 370
480 490 500 510 520 530
pF1KE2 LDLNAPGRATGAVSYTMLYNCLDFPAGVVPVTTVTAEDEAQMEHYRGYFGDIWDKMLQKG
..: .:: ... : .:. :. . .. : :.: . .
XP_011 --HHVPLTRPFNFAYTGVFSALGLPVTQCPLGLNAKGLPLGIQVVAGPFNDHLTLAVAQY
380 390 400 410 420 430
540 550 560 570
pF1KE2 MKKSVGLPVAVQCVALPWQEELCLRFMREVERLMTPEKQSS
..:. :
XP_011 LEKTFGGWVCPGKF
440
>>XP_005262042 (OMIM: 300654) PREDICTED: fatty-acid amid (449 aa)
initn: 423 init1: 375 opt: 383 Z-score: 396.5 bits: 82.9 E(87180): 2.5e-15
Smith-Waterman score: 420; 27.6% identity (54.8% similar) in 456 aa overlap (106-544:12-441)
80 90 100 110 120 130
pF1KE2 ALPLPQLVQKLHSRELAPEAVLFTYVGKAWEVNKGTNCVTSYLADCETQLSQATRQGL--
:. : .. : . :: : : ..:: ..
XP_005 MINGIVKYRFEEAMKEAHAVDQKLA--EKQEDEATLENKWP
10 20 30
140 150 160 170 180 190
pF1KE2 LYGVPVSLKECFTYKGQDSTLGLSLNEGVPAECDSVVVHVLKLQGAVPFVHTNVPQSMFS
. :::...:: : .:. .. :: . . :. :..:: .:: ::.:. :: . .
XP_005 FLGVPLTVKEAFQLQGMPNSSGLMNRRDAIAKTDATVVALLKGAGAIPLGITNCSELCMW
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE2 YDCSNPLFGQTVNPWKSSKSPGGSSGGEGALIGSGGSPLGLGTDIGGSIRFPSSFCGICG
:. :: ..:.. ::. .. :::::::: .... : .:.:.:::::::.:. : :: :
XP_005 YESSNKIYGRSNNPYDLQHIVGGSSGGEGCTLAAACSVIGVGSDIGGSIRMPAFFNGIFG
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE2 LKPTGNRLSKSGLKGCVYGQEAVRLSVGPMARDVESLALCLRALLCEDMFRLDPTVPPLP
::. . . ..: . : . . : .::: : .:.:: :... : . :
XP_005 HKPSPGVVPNKGQFPLAVGAQELFLCTGPMCRYAEDLAPMLKVMA-------GPGIKRLK
160 170 180 190 200 210
320 330 340 350 360 370
pF1KE2 FREEVYTSSQPLRVGYYETDNYTMPSPAMRRAVLETKQSLEAAGHTLVPFLPSNIPHA-L
. .:. . :. ..: :. .. . . .. :.... . : : .: ... :. :
XP_005 LDTKVHL--KDLKFYWMEHDGGSFLMSKVDQDLIMTQKKVVV--H-LETILGASVQHVKL
220 230 240 250 260
380 390 400 410 420
pF1KE2 ETLSTG-----GLFSDGGHTFLQNFKGDFVDPCLGDL---VSIL-KLPQWLKGLLAFLVK
. .. . ...: :: . : ::: ::: :: : .: .: :: .. .
XP_005 KKMKYSFQLWIAMMSAKGHDGKEPVK--FVD-LLGDHGKHVSPLWELIKWCLGLSVYTI-
270 280 290 300 310 320
430 440 450 460 470
pF1KE2 PLLPRLSAFLSNMKSR-SAGKLWELQHEIEVYRKTVIAQWRALDLDVVLT----PMLAPA
: .. : . : : : : ... : :: .. . : : :. : .::
XP_005 ---PSIGLALLEEKLRYSNEKYQKFKAVEESLRKELVDM---LGDDGVFLYPSHPTVAPK
330 340 350 360 370
480 490 500 510 520 530
pF1KE2 LDLNAPGRATGAVSYTMLYNCLDFPAGVVPVTTVTAEDEAQMEHYRGYFGDIWDKMLQKG
..: .:: ... : .:. :. . .. : :.: . .
XP_005 --HHVPLTRPFNFAYTGVFSALGLPVTQCPLGLNAKGLPLGIQVVAGPFNDHLTLAVAQY
380 390 400 410 420 430
540 550 560 570
pF1KE2 MKKSVGLPVAVQCVALPWQEELCLRFMREVERLMTPEKQSS
..:. :
XP_005 LEKTFGGWVCPGKF
440
>>XP_016884779 (OMIM: 300654) PREDICTED: fatty-acid amid (487 aa)
initn: 375 init1: 375 opt: 383 Z-score: 396.0 bits: 83.0 E(87180): 2.6e-15
Smith-Waterman score: 427; 27.8% identity (56.0% similar) in 425 aa overlap (61-459:35-440)
40 50 60 70 80 90
pF1KE2 WSGRRTARGAVVRARQRQRAGLENMDRAAQRFRLQNPDLDSEALLALPLPQLVQKLHSRE
.: ..: .: :: : ::.. ...:.
XP_016 FTARIQLFLLRALGFLIGLVGRAALVLGGPKFASKTPRPVTEPLLLLSGMQLAKLIRQRK
10 20 30 40 50 60
100 110 120 130
pF1KE2 LAPEAVLFTYVGKAWEVNKGTNCVTSYLADCETQLSQATRQGL---------------LY
. :. .:... .:: : ...: . . ..:. : : .
XP_016 VKCIDVVQAYINRIKDVNPMINGIVKYRFEEAMKEAHAVDQKLAEKQEDEATLENKWPFL
70 80 90 100 110 120
140 150 160 170 180 190
pF1KE2 GVPVSLKECFTYKGQDSTLGLSLNEGVPAECDSVVVHVLKLQGAVPFVHTNVPQSMFSYD
:::...:: : .:. .. :: . . :. :..:: .:: ::.:. :: . . :.
XP_016 GVPLTVKEAFQLQGMPNSSGLMNRRDAIAKTDATVVALLKGAGAIPLGITNCSELCMWYE
130 140 150 160 170 180
200 210 220 230 240 250
pF1KE2 CSNPLFGQTVNPWKSSKSPGGSSGGEGALIGSGGSPLGLGTDIGGSIRFPSSFCGICGLK
:: ..:.. ::. .. :::::::: .... : .:.:.:::::::.:. : :: : :
XP_016 SSNKIYGRSNNPYDLQHIVGGSSGGEGCTLAAACSVIGVGSDIGGSIRMPAFFNGIFGHK
190 200 210 220 230 240
260 270 280 290 300 310
pF1KE2 PTGNRLSKSGLKGCVYGQEAVRLSVGPMARDVESLALCLRALLCEDMFRLDPTVPPLPFR
:. . . ..: . : . . : .::: : .:.:: :... : . : .
XP_016 PSPGVVPNKGQFPLAVGAQELFLCTGPMCRYAEDLAPMLKVMA-------GPGIKRLKLD
250 260 270 280 290
320 330 340 350 360 370
pF1KE2 EEVYTSSQPLRVGYYETDNYTMPSPAMRRAVLETKQSLEAAGHTLVPFLPSNIPHA-LET
.:. . :. ..: :. .. . . .. :.... . : : .: ... :. :.
XP_016 TKVHL--KDLKFYWMEHDGGSFLMSKVDQDLIMTQKKVVV--H-LETILGASVQHVKLKK
300 310 320 330 340 350
380 390 400 410 420
pF1KE2 LSTG-----GLFSDGGHTFLQNFKGDFVDPCLGDL---VSIL-KLPQWLKGLLAFLVKPL
.. . ...: :: . : ::: ::: :: : .: .: :: .. .
XP_016 MKYSFQLWIAMMSAKGHDGKEPVK--FVD-LLGDHGKHVSPLWELIKWCLGLSVYTI---
360 370 380 390 400
430 440 450 460 470 480
pF1KE2 LPRLSAFLSNMKSR-SAGKLWELQHEIEVYRKTVIAQWRALDLDVVLTPMLAPALDLNAP
: .. : . : : : : ... : :: ..
XP_016 -PSIGLALLEEKLRYSNEKYQKFKAVEESLRKELVDMLGDDGVFLYPSHPTVAPKHHVPL
410 420 430 440 450 460
490 500 510 520 530 540
pF1KE2 GRATGAVSYTMLYNCLDFPAGVVPVTTVTAEDEAQMEHYRGYFGDIWDKMLQKGMKKSVG
XP_016 TRPFNFAYTGVCTQRSLGPFIS
470 480
>>XP_005262039 (OMIM: 300654) PREDICTED: fatty-acid amid (492 aa)
initn: 423 init1: 375 opt: 383 Z-score: 396.0 bits: 83.0 E(87180): 2.6e-15
Smith-Waterman score: 409; 31.5% identity (60.4% similar) in 260 aa overlap (61-305:35-294)
40 50 60 70 80 90
pF1KE2 WSGRRTARGAVVRARQRQRAGLENMDRAAQRFRLQNPDLDSEALLALPLPQLVQKLHSRE
.: ..: .: :: : ::.. ...:.
XP_005 FTARIQLFLLRALGFLIGLVGRAALVLGGPKFASKTPRPVTEPLLLLSGMQLAKLIRQRK
10 20 30 40 50 60
100 110 120 130
pF1KE2 LAPEAVLFTYVGKAWEVNKGTNCVTSYLADCETQLSQATRQGL---------------LY
. :. .:... .:: : ...: . . ..:. : : .
XP_005 VKCIDVVQAYINRIKDVNPMINGIVKYRFEEAMKEAHAVDQKLAEKQEDEATLENKWPFL
70 80 90 100 110 120
140 150 160 170 180 190
pF1KE2 GVPVSLKECFTYKGQDSTLGLSLNEGVPAECDSVVVHVLKLQGAVPFVHTNVPQSMFSYD
:::...:: : .:. .. :: . . :. :..:: .:: ::.:. :: . . :.
XP_005 GVPLTVKEAFQLQGMPNSSGLMNRRDAIAKTDATVVALLKGAGAIPLGITNCSELCMWYE
130 140 150 160 170 180
200 210 220 230 240 250
pF1KE2 CSNPLFGQTVNPWKSSKSPGGSSGGEGALIGSGGSPLGLGTDIGGSIRFPSSFCGICGLK
:: ..:.. ::. .. :::::::: .... : .:.:.:::::::.:. : :: : :
XP_005 SSNKIYGRSNNPYDLQHIVGGSSGGEGCTLAAACSVIGVGSDIGGSIRMPAFFNGIFGHK
190 200 210 220 230 240
260 270 280 290 300 310
pF1KE2 PTGNRLSKSGLKGCVYGQEAVRLSVGPMARDVESLALCLRALLCEDMFRLDPTVPPLPFR
:. . . ..: . : . . : .::: : .:.:: :... . ::
XP_005 PSPGVVPNKGQFPLAVGAQELFLCTGPMCRYAEDLAPMLKVMAGPGIKRLKLDTKVHLKD
250 260 270 280 290 300
320 330 340 350 360 370
pF1KE2 EEVYTSSQPLRVGYYETDNYTMPSPAMRRAVLETKQSLEAAGHTLVPFLPSNIPHALETL
XP_005 LKFYWMEHDGGSFLMSKVDQDLIMTQKKEPVKFVDLLGDHGKHVSPLWELIKWCLGLSVY
310 320 330 340 350 360
>>NP_777572 (OMIM: 300654) fatty-acid amide hydrolase 2 (532 aa)
initn: 423 init1: 375 opt: 383 Z-score: 395.5 bits: 83.0 E(87180): 2.8e-15
Smith-Waterman score: 446; 26.3% identity (53.7% similar) in 514 aa overlap (61-544:35-524)
40 50 60 70 80 90
pF1KE2 WSGRRTARGAVVRARQRQRAGLENMDRAAQRFRLQNPDLDSEALLALPLPQLVQKLHSRE
.: ..: .: :: : ::.. ...:.
NP_777 FTARIQLFLLRALGFLIGLVGRAALVLGGPKFASKTPRPVTEPLLLLSGMQLAKLIRQRK
10 20 30 40 50 60
100 110 120 130
pF1KE2 LAPEAVLFTYVGKAWEVNKGTNCVTSYLADCETQLSQATRQGL---------------LY
. :. .:... .:: : ...: . . ..:. : : .
NP_777 VKCIDVVQAYINRIKDVNPMINGIVKYRFEEAMKEAHAVDQKLAEKQEDEATLENKWPFL
70 80 90 100 110 120
140 150 160 170 180 190
pF1KE2 GVPVSLKECFTYKGQDSTLGLSLNEGVPAECDSVVVHVLKLQGAVPFVHTNVPQSMFSYD
:::...:: : .:. .. :: . . :. :..:: .:: ::.:. :: . . :.
NP_777 GVPLTVKEAFQLQGMPNSSGLMNRRDAIAKTDATVVALLKGAGAIPLGITNCSELCMWYE
130 140 150 160 170 180
200 210 220 230 240 250
pF1KE2 CSNPLFGQTVNPWKSSKSPGGSSGGEGALIGSGGSPLGLGTDIGGSIRFPSSFCGICGLK
:: ..:.. ::. .. :::::::: .... : .:.:.:::::::.:. : :: : :
NP_777 SSNKIYGRSNNPYDLQHIVGGSSGGEGCTLAAACSVIGVGSDIGGSIRMPAFFNGIFGHK
190 200 210 220 230 240
260 270 280 290 300 310
pF1KE2 PTGNRLSKSGLKGCVYGQEAVRLSVGPMARDVESLALCLRALLCEDMFRLDPTVPPLPFR
:. . . ..: . : . . : .::: : .:.:: :... : . : .
NP_777 PSPGVVPNKGQFPLAVGAQELFLCTGPMCRYAEDLAPMLKVMA-------GPGIKRLKLD
250 260 270 280 290
320 330 340 350 360 370
pF1KE2 EEVYTSSQPLRVGYYETDNYTMPSPAMRRAVLETKQSLEAAGHTLVPFLPSNIPHA-LET
.:. . :. ..: :. .. . . .. :.... . : : .: ... :. :.
NP_777 TKVHL--KDLKFYWMEHDGGSFLMSKVDQDLIMTQKKVVV--H-LETILGASVQHVKLKK
300 310 320 330 340 350
380 390 400 410 420
pF1KE2 LSTG-----GLFSDGGHTFLQNFKGDFVDPCLGDL---VSIL-KLPQWLKGLLAFLVKPL
.. . ...: :: . : ::: ::: :: : .: .: :: .. .
NP_777 MKYSFQLWIAMMSAKGHDGKEPVK--FVD-LLGDHGKHVSPLWELIKWCLGLSVYTI---
360 370 380 390 400
430 440 450 460 470 480
pF1KE2 LPRLSAFLSNMKSR-SAGKLWELQHEIEVYRKTVIAQWRALDLDVVLT----PMLAPALD
: .. : . : : : : ... : :: .. . : : :. : .::
NP_777 -PSIGLALLEEKLRYSNEKYQKFKAVEESLRKELVDM---LGDDGVFLYPSHPTVAPK--
410 420 430 440 450 460
490 500 510 520 530 540
pF1KE2 LNAPGRATGAVSYTMLYNCLDFPAGVVPVTTVTAEDEAQMEHYRGYFGDIWDKMLQKGMK
..: .:: ... : .:. :. . .. : :.: . . ..
NP_777 HHVPLTRPFNFAYTGVFSALGLPVTQCPLGLNAKGLPLGIQVVAGPFNDHLTLAVAQYLE
470 480 490 500 510 520
550 560 570
pF1KE2 KSVGLPVAVQCVALPWQEELCLRFMREVERLMTPEKQSS
:. :
NP_777 KTFGGWVCPGKF
530
579 residues in 1 query sequences
61989856 residues in 87180 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon May 22 10:35:03 2017 done: Mon May 22 10:35:04 2017
Total Scan time: 9.860 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]