Result of FASTA (omim) for
pFN21AE2571
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2571, 1326 aa
1>>>pF1KE2571 1326 - 1326 aa - 1326 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.5868+/-0.000524; mu= -1.8380+/- 0.033
mean_var=277.1228+/-59.300, 0's: 0 Z-trim(116.1): 56 B-trim: 2158 in 2/59
Lambda= 0.077044
statistics sampled from 26930 (26986) to 26930 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.654), E-opt: 0.2 (0.316), width: 16
Scan time: 16.320
The best scores are: opt bits E(85289)
NP_001167448 (OMIM: 609593) F-actin-uncapping prot (1365) 7634 863.5 0
NP_060110 (OMIM: 609593) F-actin-uncapping protein (1371) 7619 861.8 0
XP_005249275 (OMIM: 609593) PREDICTED: F-actin-unc (1421) 7619 861.9 0
XP_016866502 (OMIM: 609593) PREDICTED: F-actin-unc (1419) 7616 861.5 0
XP_016866505 (OMIM: 609593) PREDICTED: F-actin-unc (1375) 7601 859.8 0
XP_016866500 (OMIM: 609593) PREDICTED: F-actin-unc (1425) 7601 859.9 0
XP_016866499 (OMIM: 609593) PREDICTED: F-actin-unc (1427) 7574 856.9 0
XP_016866503 (OMIM: 609593) PREDICTED: F-actin-unc (1411) 7055 799.2 0
XP_016866506 (OMIM: 609593) PREDICTED: F-actin-unc ( 944) 5840 664.0 1.4e-189
XP_016866504 (OMIM: 609593) PREDICTED: F-actin-unc (1381) 5840 664.1 1.9e-189
XP_016866501 (OMIM: 609593) PREDICTED: F-actin-unc (1425) 5840 664.1 1.9e-189
XP_016866498 (OMIM: 609593) PREDICTED: F-actin-unc (1430) 5840 664.1 1.9e-189
XP_016866497 (OMIM: 609593) PREDICTED: F-actin-unc (1431) 5840 664.1 1.9e-189
NP_612369 (OMIM: 614716) capping protein, Arp2/3 a (1372) 2824 328.9 1.5e-88
XP_016877240 (OMIM: 614716) PREDICTED: leucine-ric (1297) 2520 295.1 2.2e-78
XP_011535602 (OMIM: 614716) PREDICTED: leucine-ric (1320) 2520 295.1 2.2e-78
NP_001303955 (OMIM: 610859) capping protein, Arp2/ (1372) 2088 247.1 6.5e-64
XP_011521176 (OMIM: 610859) PREDICTED: F-actin-unc (1377) 2038 241.5 3.1e-62
XP_016878442 (OMIM: 610859) PREDICTED: F-actin-unc (1399) 2038 241.5 3.1e-62
XP_011521177 (OMIM: 610859) PREDICTED: F-actin-unc (1410) 2038 241.5 3.1e-62
NP_001013860 (OMIM: 610859) capping protein, Arp2/ (1435) 1233 152.1 2.7e-35
>>NP_001167448 (OMIM: 609593) F-actin-uncapping protein (1365 aa)
initn: 7590 init1: 7590 opt: 7634 Z-score: 4600.0 bits: 863.5 E(85289): 0
Smith-Waterman score: 8453; 97.1% identity (97.1% similar) in 1358 aa overlap (1-1319:1-1358)
10 20 30 40 50 60
pF1KE2 MTEESSDVPRELIESIKDVIGRKIKISVKKKVKLEVKGDKVENKVLVLTSCRAFLVTARI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTEESSDVPRELIESIKDVIGRKIKISVKKKVKLEVKGDKVENKVLVLTSCRAFLVTARI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PTKLELTFSYLEIHGVVCSKSAQMIVETEKCSISMKMASPEDVSEVLAHIGTCLRKIFPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTKLELTFSYLEIHGVVCSKSAQMIVETEKCSISMKMASPEDVSEVLAHIGTCLRKIFPG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 LSPVRIMKKVSMEPSERLASLQALWDSQTVAEQGPCGGFSQMYACVCDWLGFSYREEVQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSPVRIMKKVSMEPSERLASLQALWDSQTVAEQGPCGGFSQMYACVCDWLGFSYREEVQW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 DVDTIYLTQDTRELNLQDFSHLDHRDLIPIIAALEYNQWFTKLSSKDLKLSTDVCEQILR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVDTIYLTQDTRELNLQDFSHLDHRDLIPIIAALEYNQWFTKLSSKDLKLSTDVCEQILR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VVSRSNRLEELVLENAGLRTDFAQKLASALAHNPNSGLHTINLAGNPLEDRGVSSLSIQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVSRSNRLEELVLENAGLRTDFAQKLASALAHNPNSGLHTINLAGNPLEDRGVSSLSIQF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 AKLPKGLKHLNLSKTSLSPKGVNSLSQSLSANPLTASTLVHLDLSGNVLRGDDLSHMYNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKLPKGLKHLNLSKTSLSPKGVNSLSQSLSANPLTASTLVHLDLSGNVLRGDDLSHMYNF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 LAQPNAIVHLDLSNTECSLDMVCGALLRGCLQYLAVLNLSRTVFSHRKGKEVPPSFKQFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAQPNAIVHLDLSNTECSLDMVCGALLRGCLQYLAVLNLSRTVFSHRKGKEVPPSFKQFF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 SSSLALMHINLSGTKLSPEPLKALLLGLACNHNLKGVSLDLSNCELRSGGAQVLEGCIAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSLALMHINLSGTKLSPEPLKALLLGLACNHNLKGVSLDLSNCELRSGGAQVLEGCIAE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 IHNITSLDISDNGLESDLSTLIVWLSKNRSIQHLALGKNFNNMKSKNLTPVLDNLVQMIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IHNITSLDISDNGLESDLSTLIVWLSKNRSIQHLALGKNFNNMKSKNLTPVLDNLVQMIQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 DEESPLQSLSLADSKLKTEVTIIINALGSNTSLTKVDISGNGMGDMGAKMLAKALQINTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEESPLQSLSLADSKLKTEVTIIINALGSNTSLTKVDISGNGMGDMGAKMLAKALQINTK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 LRTVIWDKNNITAQGFQDIAVAMEKNYTLRFMPIPMYDASQALKTNPEKTEDALQKIENY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRTVIWDKNNITAQGFQDIAVAMEKNYTLRFMPIPMYDASQALKTNPEKTEDALQKIENY
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 LLRNHETRKYLQEQAYRLQQGIVTSTTQQMIDRICVKVQDHLNSLRNCGGDAIQEDLKSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLRNHETRKYLQEQAYRLQQGIVTSTTQQMIDRICVKVQDHLNSLRNCGGDAIQEDLKSA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 ERLMRDAKNSKTLLPNLYHVGGASWAGASGLLSSPIQETLESMAGEVTRVVDEQLKALLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERLMRDAKNSKTLLPNLYHVGGASWAGASGLLSSPIQETLESMAGEVTRVVDEQLKALLE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 SMVDAAENLCPNVMKKAHIRQDLIHASTEKISIPRTFVKNVLLEQSGIDILNKISEVKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMVDAAENLCPNVMKKAHIRQDLIHASTEKISIPRTFVKNVLLEQSGIDILNKISEVKLT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 VASFLSDRIVDEILDALSHCHHKLADHFSRRGKTLPQQESLEIELAEEKPVKRSIITVEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VASFLSDRIVDEILDALSHCHHKLADHFSRRGKTLPQQESLEIELAEEKPVKRSIITVEE
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 LTEIERLEDLDTCMMTPKSKRKSIHSRMLRPVSRAFEMEFDLDKALEEVPIHIEDPPFPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTEIERLEDLDTCMMTPKSKRKSIHSRMLRPVSRAFEMEFDLDKALEEVPIHIEDPPFPS
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 LRQEKRSSGFISELPSEEGKKLEHFTKLRPKRNKKQQPTQAAVCAANIVSQDGEQNGLMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRQEKRSSGFISELPSEEGKKLEHFTKLRPKRNKKQQPTQAAVCAANIVSQDGEQNGLMG
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 RVDEGVDEFFTKKVTKMDSKKWSTRGSESHELNEGGDEKKKRDSRKSSGFLNLIKSRSKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVDEGVDEFFTKKVTKMDSKKWSTRGSESHELNEGGDEKKKRDSRKSSGFLNLIKSRSKS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 ERPPTILMTEEPSSPKGAVRSPPVDCPRKDTKAAEHNGNSERIEEIKTPDSFEESQGEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERPPTILMTEEPSSPKGAVRSPPVDCPRKDTKAAEHNGNSERIEEIKTPDSFEESQGEEI
1090 1100 1110 1120 1130 1140
1150 1160 1170
pF1KE2 GKVERSDSKSSPQAGRRYGVQVMGSGLLAEMKAKQE------------------------
::::::::::::::::::::::::::::::::::::
NP_001 GKVERSDSKSSPQAGRRYGVQVMGSGLLAEMKAKQEKRAACAQKKLGNDAVSQDSSSPAL
1150 1160 1170 1180 1190 1200
1180 1190 1200 1210 1220
pF1KE2 ---------------NRFGLGTPEKNTKAEPKAEAGSRSRSSSSTPTSPKPLLQSPKPSL
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGVERSDGGGAGLPENRFGLGTPEKNTKAEPKAEAGSRSRSSSSTPTSPKPLLQSPKPSL
1210 1220 1230 1240 1250 1260
1230 1240 1250 1260 1270 1280
pF1KE2 AARPVIPQKPRTASRPDDIPDSPSSPKVALLPPVLKKVPSDKERDGQSSPQPSPRTFSQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AARPVIPQKPRTASRPDDIPDSPSSPKVALLPPVLKKVPSDKERDGQSSPQPSPRTFSQE
1270 1280 1290 1300 1310 1320
1290 1300 1310 1320
pF1KE2 VSRRSWGQQAQEYQEQKQRSSSKDGHQGSKSNDSGEEAEKEFIFV
::::::::::::::::::::::::::::::::::::::
NP_001 VSRRSWGQQAQEYQEQKQRSSSKDGHQGSKSNDSGEEAEKEFIFV
1330 1340 1350 1360
>>NP_060110 (OMIM: 609593) F-actin-uncapping protein LRR (1371 aa)
initn: 7690 init1: 7590 opt: 7619 Z-score: 4590.9 bits: 861.8 E(85289): 0
Smith-Waterman score: 8403; 96.7% identity (96.7% similar) in 1358 aa overlap (1-1313:1-1358)
10 20 30 40 50 60
pF1KE2 MTEESSDVPRELIESIKDVIGRKIKISVKKKVKLEVKGDKVENKVLVLTSCRAFLVTARI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MTEESSDVPRELIESIKDVIGRKIKISVKKKVKLEVKGDKVENKVLVLTSCRAFLVTARI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PTKLELTFSYLEIHGVVCSKSAQMIVETEKCSISMKMASPEDVSEVLAHIGTCLRKIFPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 PTKLELTFSYLEIHGVVCSKSAQMIVETEKCSISMKMASPEDVSEVLAHIGTCLRKIFPG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 LSPVRIMKKVSMEPSERLASLQALWDSQTVAEQGPCGGFSQMYACVCDWLGFSYREEVQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LSPVRIMKKVSMEPSERLASLQALWDSQTVAEQGPCGGFSQMYACVCDWLGFSYREEVQW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 DVDTIYLTQDTRELNLQDFSHLDHRDLIPIIAALEYNQWFTKLSSKDLKLSTDVCEQILR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 DVDTIYLTQDTRELNLQDFSHLDHRDLIPIIAALEYNQWFTKLSSKDLKLSTDVCEQILR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VVSRSNRLEELVLENAGLRTDFAQKLASALAHNPNSGLHTINLAGNPLEDRGVSSLSIQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 VVSRSNRLEELVLENAGLRTDFAQKLASALAHNPNSGLHTINLAGNPLEDRGVSSLSIQF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 AKLPKGLKHLNLSKTSLSPKGVNSLSQSLSANPLTASTLVHLDLSGNVLRGDDLSHMYNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 AKLPKGLKHLNLSKTSLSPKGVNSLSQSLSANPLTASTLVHLDLSGNVLRGDDLSHMYNF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 LAQPNAIVHLDLSNTECSLDMVCGALLRGCLQYLAVLNLSRTVFSHRKGKEVPPSFKQFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LAQPNAIVHLDLSNTECSLDMVCGALLRGCLQYLAVLNLSRTVFSHRKGKEVPPSFKQFF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 SSSLALMHINLSGTKLSPEPLKALLLGLACNHNLKGVSLDLSNCELRSGGAQVLEGCIAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SSSLALMHINLSGTKLSPEPLKALLLGLACNHNLKGVSLDLSNCELRSGGAQVLEGCIAE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 IHNITSLDISDNGLESDLSTLIVWLSKNRSIQHLALGKNFNNMKSKNLTPVLDNLVQMIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 IHNITSLDISDNGLESDLSTLIVWLSKNRSIQHLALGKNFNNMKSKNLTPVLDNLVQMIQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 DEESPLQSLSLADSKLKTEVTIIINALGSNTSLTKVDISGNGMGDMGAKMLAKALQINTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 DEESPLQSLSLADSKLKTEVTIIINALGSNTSLTKVDISGNGMGDMGAKMLAKALQINTK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 LRTVIWDKNNITAQGFQDIAVAMEKNYTLRFMPIPMYDASQALKTNPEKTEDALQKIENY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LRTVIWDKNNITAQGFQDIAVAMEKNYTLRFMPIPMYDASQALKTNPEKTEDALQKIENY
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 LLRNHETRKYLQEQAYRLQQGIVTSTTQQMIDRICVKVQDHLNSLRNCGGDAIQEDLKSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LLRNHETRKYLQEQAYRLQQGIVTSTTQQMIDRICVKVQDHLNSLRNCGGDAIQEDLKSA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 ERLMRDAKNSKTLLPNLYHVGGASWAGASGLLSSPIQETLESMAGEVTRVVDEQLKALLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 ERLMRDAKNSKTLLPNLYHVGGASWAGASGLLSSPIQETLESMAGEVTRVVDEQLKALLE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 SMVDAAENLCPNVMKKAHIRQDLIHASTEKISIPRTFVKNVLLEQSGIDILNKISEVKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SMVDAAENLCPNVMKKAHIRQDLIHASTEKISIPRTFVKNVLLEQSGIDILNKISEVKLT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 VASFLSDRIVDEILDALSHCHHKLADHFSRRGKTLPQQESLEIELAEEKPVKRSIITVEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 VASFLSDRIVDEILDALSHCHHKLADHFSRRGKTLPQQESLEIELAEEKPVKRSIITVEE
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 LTEIERLEDLDTCMMTPKSKRKSIHSRMLRPVSRAFEMEFDLDKALEEVPIHIEDPPFPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LTEIERLEDLDTCMMTPKSKRKSIHSRMLRPVSRAFEMEFDLDKALEEVPIHIEDPPFPS
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 LRQEKRSSGFISELPSEEGKKLEHFTKLRPKRNKKQQPTQAAVCAANIVSQDGEQNGLMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LRQEKRSSGFISELPSEEGKKLEHFTKLRPKRNKKQQPTQAAVCAANIVSQDGEQNGLMG
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 RVDEGVDEFFTKKVTKMDSKKWSTRGSESHELNEGGDEKKKRDSRKSSGFLNLIKSRSKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 RVDEGVDEFFTKKVTKMDSKKWSTRGSESHELNEGGDEKKKRDSRKSSGFLNLIKSRSKS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 ERPPTILMTEEPSSPKGAVRSPPVDCPRKDTKAAEHNGNSERIEEIKTPDSFEESQGEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 ERPPTILMTEEPSSPKGAVRSPPVDCPRKDTKAAEHNGNSERIEEIKTPDSFEESQGEEI
1090 1100 1110 1120 1130 1140
1150 1160 1170
pF1KE2 GKVERSDSKSSPQAGRRYGVQVMGSGLLAEMKAKQE------------------------
::::::::::::::::::::::::::::::::::::
NP_060 GKVERSDSKSSPQAGRRYGVQVMGSGLLAEMKAKQEKRAACAQKKLGNDAVSQDSSSPAL
1150 1160 1170 1180 1190 1200
1180 1190 1200 1210
pF1KE2 ---------------------NRFGLGTPEKNTKAEPKAEAGSRSRSSSSTPTSPKPLLQ
:::::::::::::::::::::::::::::::::::::::
NP_060 SGVERSDGGGAVPKLHPGLPENRFGLGTPEKNTKAEPKAEAGSRSRSSSSTPTSPKPLLQ
1210 1220 1230 1240 1250 1260
1220 1230 1240 1250 1260 1270
pF1KE2 SPKPSLAARPVIPQKPRTASRPDDIPDSPSSPKVALLPPVLKKVPSDKERDGQSSPQPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SPKPSLAARPVIPQKPRTASRPDDIPDSPSSPKVALLPPVLKKVPSDKERDGQSSPQPSP
1270 1280 1290 1300 1310 1320
1280 1290 1300 1310 1320
pF1KE2 RTFSQEVSRRSWGQQAQEYQEQKQRSSSKDGHQGSKSNDSGEEAEKEFIFV
::::::::::::::::::::::::::::::::::::::
NP_060 RTFSQEVSRRSWGQQAQEYQEQKQRSSSKDGHQGSKSNDSGEEAEKEFIFV
1330 1340 1350 1360 1370
>>XP_005249275 (OMIM: 609593) PREDICTED: F-actin-uncappi (1421 aa)
initn: 7975 init1: 7590 opt: 7619 Z-score: 4590.7 bits: 861.9 E(85289): 0
Smith-Waterman score: 8213; 94.8% identity (96.0% similar) in 1358 aa overlap (1-1313:1-1353)
10 20 30 40 50 60
pF1KE2 MTEESSDVPRELIESIKDVIGRKIKISVKKKVKLEVKGDKVENKVLVLTSCRAFLVTARI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTEESSDVPRELIESIKDVIGRKIKISVKKKVKLEVKGDKVENKVLVLTSCRAFLVTARI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PTKLELTFSYLEIHGVVCSKSAQMIVETEKCSISMKMASPEDVSEVLAHIGTCLRKIFPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTKLELTFSYLEIHGVVCSKSAQMIVETEKCSISMKMASPEDVSEVLAHIGTCLRKIFPG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 LSPVRIMKKVSMEPSERLASLQALWDSQTVAEQGPCGGFSQMYACVCDWLGFSYREEVQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSPVRIMKKVSMEPSERLASLQALWDSQTVAEQGPCGGFSQMYACVCDWLGFSYREEVQW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 DVDTIYLTQDTRELNLQDFSHLDHRDLIPIIAALEYNQWFTKLSSKDLKLSTDVCEQILR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DVDTIYLTQDTRELNLQDFSHLDHRDLIPIIAALEYNQWFTKLSSKDLKLSTDVCEQILR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VVSRSNRLEELVLENAGLRTDFAQKLASALAHNPNSGLHTINLAGNPLEDRGVSSLSIQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVSRSNRLEELVLENAGLRTDFAQKLASALAHNPNSGLHTINLAGNPLEDRGVSSLSIQF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 AKLPKGLKHLNLSKTSLSPKGVNSLSQSLSANPLTASTLVHLDLSGNVLRGDDLSHMYNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AKLPKGLKHLNLSKTSLSPKGVNSLSQSLSANPLTASTLVHLDLSGNVLRGDDLSHMYNF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 LAQPNAIVHLDLSNTECSLDMVCGALLRGCLQYLAVLNLSRTVFSHRKGKEVPPSFKQFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LAQPNAIVHLDLSNTECSLDMVCGALLRGCLQYLAVLNLSRTVFSHRKGKEVPPSFKQFF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 SSSLALMHINLSGTKLSPEPLKALLLGLACNHNLKGVSLDLSNCELRSGGAQVLEGCIAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSSLALMHINLSGTKLSPEPLKALLLGLACNHNLKGVSLDLSNCELRSGGAQVLEGCIAE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 IHNITSLDISDNGLESDLSTLIVWLSKNRSIQHLALGKNFNNMKSKNLTPVLDNLVQMIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IHNITSLDISDNGLESDLSTLIVWLSKNRSIQHLALGKNFNNMKSKNLTPVLDNLVQMIQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 DEESPLQSLSLADSKLKTEVTIIINALGSNTSLTKVDISGNGMGDMGAKMLAKALQINTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DEESPLQSLSLADSKLKTEVTIIINALGSNTSLTKVDISGNGMGDMGAKMLAKALQINTK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 LRTVIWDKNNITAQGFQDIAVAMEKNYTLRFMPIPMYDASQALKTNPEKTEDALQKIENY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRTVIWDKNNITAQGFQDIAVAMEKNYTLRFMPIPMYDASQALKTNPEKTEDALQKIENY
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 LLRNHETRKYLQEQAYRLQQGIVTSTTQQMIDRICVKVQDHLNSLRNCGGDAIQEDLKSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLRNHETRKYLQEQAYRLQQGIVTSTTQQMIDRICVKVQDHLNSLRNCGGDAIQEDLKSA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 ERLMRDAKNSKTLLPNLYHVGGASWAGASGLLSSPIQETLESMAGEVTRVVDEQLKALLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERLMRDAKNSKTLLPNLYHVGGASWAGASGLLSSPIQETLESMAGEVTRVVDEQLKALLE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 SMVDAAENLCPNVMKKAHIRQDLIHASTEKISIPRTFVKNVLLEQSGIDILNKISEVKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SMVDAAENLCPNVMKKAHIRQDLIHASTEKISIPRTFVKNVLLEQSGIDILNKISEVKLT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 VASFLSDRIVDEILDALSHCHHKLADHFSRRGKTLPQQESLEIELAEEKPVKRSIITVEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VASFLSDRIVDEILDALSHCHHKLADHFSRRGKTLPQQESLEIELAEEKPVKRSIITVEE
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 LTEIERLEDLDTCMMTPKSKRKSIHSRMLRPVSRAFEMEFDLDKALEEVPIHIEDPPFPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTEIERLEDLDTCMMTPKSKRKSIHSRMLRPVSRAFEMEFDLDKALEEVPIHIEDPPFPS
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 LRQEKRSSGFISELPSEEGKKLEHFTKLRPKRNKKQQPTQAAVCAANIVSQDGEQNGLMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRQEKRSSGFISELPSEEGKKLEHFTKLRPKRNKKQQPTQAAVCAANIVSQDGEQNGLMG
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 RVDEGVDEFFTKKVTKMDSKKWSTRGSESHELNEGGDEKKKRDSRKSSGFLNLIKSRSKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RVDEGVDEFFTKKVTKMDSKKWSTRGSESHELNEGGDEKKKRDSRKSSGFLNLIKSRSKS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 ERPPTILMTEEPSSPKGAVRSPPVDCPRKDTKAAEHNGNSERIEEIKTPDSFEESQGEEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERPPTILMTEEPSSPKGAVRSPPVDCPRKDTKAAEHNGNSERIEEIKTPDSFEESQGEEI
1090 1100 1110 1120 1130 1140
1150 1160 1170
pF1KE2 GKVERSDSKSSPQAGRRYGVQVMGSGLLAEMKAKQE------------------------
::::::::::::::::::::::::::::::::::::
XP_005 GKVERSDSKSSPQAGRRYGVQVMGSGLLAEMKAKQEKRAACAQKKLGNDAVSQDSSSPAL
1150 1160 1170 1180 1190 1200
1180 1190 1200 1210
pF1KE2 ---------------------NRFGLGTPEKNTKAEPKAEAGSRSRSSSSTPTSPKPLLQ
:::::::::::::::::::::::::::::::::::::::
XP_005 SGVERSDGGGAVPKLHPGLPENRFGLGTPEKNTKAEPKAEAGSRSRSSSSTPTSPKPLLQ
1210 1220 1230 1240 1250 1260
1220 1230 1240 1250 1260 1270
pF1KE2 SPKPSLAARPVIPQKPRTASRPDDIPDSPSSPKVALLPPVLKKVPSDKERDGQSSPQPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPKPSLAARPVIPQKPRTASRPDDIPDSPSSPKVALLPPVLKKVPSDKERDGQSSPQPSP
1270 1280 1290 1300 1310 1320
1280 1290 1300 1310 1320
pF1KE2 RTFSQEVSRRSWGQQAQEYQEQKQRSSSKDGHQGSKSNDSGEEAEKEFIFV
::::::: .:. . :.......:.: . .:..:.
XP_005 RTFSQEVVQRG-----DYYKRHSDHDSGKPSSRGKRSSKLYSTIAEEEVNAIGHRKSQPT
1330 1340 1350 1360 1370
XP_005 NVSRRSWGQQAQEYQEQKQRSSSKDGHQGSKSNDSGEEAEKEFIFV
1380 1390 1400 1410 1420
>>XP_016866502 (OMIM: 609593) PREDICTED: F-actin-uncappi (1419 aa)
initn: 4861 init1: 4576 opt: 7616 Z-score: 4588.9 bits: 861.5 E(85289): 0
Smith-Waterman score: 8210; 94.6% identity (95.8% similar) in 1363 aa overlap (1-1320:1-1361)
10 20 30 40 50 60
pF1KE2 MTEESSDVPRELIESIKDVIGRKIKISVKKKVKLEVKGDKVENKVLVLTSCRAFLVTARI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTEESSDVPRELIESIKDVIGRKIKISVKKKVKLEVKGDKVENKVLVLTSCRAFLVTARI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PTKLELTFSYLEIHGVVCSKSAQMIVETEKCSISMKMASPEDVSEVLAHIGTCLRKIFPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTKLELTFSYLEIHGVVCSKSAQMIVETEKCSISMKMASPEDVSEVLAHIGTCLRKIFPG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 LSPVRIMKKVSMEPSERLASLQALWDSQTVAEQGPCGGFSQMYACVCDWLGFSYREEVQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSPVRIMKKVSMEPSERLASLQALWDSQTVAEQGPCGGFSQMYACVCDWLGFSYREEVQW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 DVDTIYLTQDTRELNLQDFSHLDHRDLIPIIAALEYNQWFTKLSSKDLKLSTDVCEQILR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVDTIYLTQDTRELNLQDFSHLDHRDLIPIIAALEYNQWFTKLSSKDLKLSTDVCEQILR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VVSRSNRLEELVLENAGLRTDFAQKLASALAHNPNSGLHTINLAGNPLEDRGVSSLSIQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVSRSNRLEELVLENAGLRTDFAQKLASALAHNPNSGLHTINLAGNPLEDRGVSSLSIQF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 AKLPKGLKHLNLSKTSLSPKGVNSLSQSLSANPLTASTLVHLDLSGNVLRGDDLSHMYNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKLPKGLKHLNLSKTSLSPKGVNSLSQSLSANPLTASTLVHLDLSGNVLRGDDLSHMYNF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 LAQPNAIVHLDLSNTECSLDMVCGALLRGCLQYLAVLNLSRTVFSHRKGKEVPPSFKQFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAQPNAIVHLDLSNTECSLDMVCGALLRGCLQYLAVLNLSRTVFSHRKGKEVPPSFKQFF
370 380 390 400 410 420
430 440 450 460 470
pF1KE2 SSSLALMHINLSGTKLSPEPLKALLLGLACNHNLKGVSLDLSNCEL----RSGGAQVLEG
:::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_016 SSSLALMHINLSGTKLSPEPLKALLLGLACNHNLKGVSLDLSNCELGHCLRSGGAQVLEG
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE2 CIAEIHNITSLDISDNGLESDLSTLIVWLSKNRSIQHLALGKNFNNMKSKNLTPVLDNLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CIAEIHNITSLDISDNGLESDLSTLIVWLSKNRSIQHLALGKNFNNMKSKNLTPVLDNLV
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE2 QMIQDEESPLQSLSLADSKLKTEVTIIINALGSNTSLTKVDISGNGMGDMGAKMLAKALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QMIQDEESPLQSLSLADSKLKTEVTIIINALGSNTSLTKVDISGNGMGDMGAKMLAKALQ
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE2 INTKLRTVIWDKNNITAQGFQDIAVAMEKNYTLRFMPIPMYDASQALKTNPEKTEDALQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INTKLRTVIWDKNNITAQGFQDIAVAMEKNYTLRFMPIPMYDASQALKTNPEKTEDALQK
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE2 IENYLLRNHETRKYLQEQAYRLQQGIVTSTTQQMIDRICVKVQDHLNSLRNCGGDAIQED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IENYLLRNHETRKYLQEQAYRLQQGIVTSTTQQMIDRICVKVQDHLNSLRNCGGDAIQED
670 680 690 700 710 720
720 730 740 750 760 770
pF1KE2 LKSAERLMRDAKNSKTLLPNLYHVGGASWAGASGLLSSPIQETLESMAGEVTRVVDEQLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKSAERLMRDAKNSKTLLPNLYHVGGASWAGASGLLSSPIQETLESMAGEVTRVVDEQLK
730 740 750 760 770 780
780 790 800 810 820 830
pF1KE2 ALLESMVDAAENLCPNVMKKAHIRQDLIHASTEKISIPRTFVKNVLLEQSGIDILNKISE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALLESMVDAAENLCPNVMKKAHIRQDLIHASTEKISIPRTFVKNVLLEQSGIDILNKISE
790 800 810 820 830 840
840 850 860 870 880 890
pF1KE2 VKLTVASFLSDRIVDEILDALSHCHHKLADHFSRRGKTLPQQESLEIELAEEKPVKRSII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKLTVASFLSDRIVDEILDALSHCHHKLADHFSRRGKTLPQQESLEIELAEEKPVKRSII
850 860 870 880 890 900
900 910 920 930 940 950
pF1KE2 TVEELTEIERLEDLDTCMMTPKSKRKSIHSRMLRPVSRAFEMEFDLDKALEEVPIHIEDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVEELTEIERLEDLDTCMMTPKSKRKSIHSRMLRPVSRAFEMEFDLDKALEEVPIHIEDP
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KE2 PFPSLRQEKRSSGFISELPSEEGKKLEHFTKLRPKRNKKQQPTQAAVCAANIVSQDGEQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFPSLRQEKRSSGFISELPSEEGKKLEHFTKLRPKRNKKQQPTQAAVCAANIVSQDGEQN
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KE2 GLMGRVDEGVDEFFTKKVTKMDSKKWSTRGSESHELNEGGDEKKKRDSRKSSGFLNLIKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLMGRVDEGVDEFFTKKVTKMDSKKWSTRGSESHELNEGGDEKKKRDSRKSSGFLNLIKS
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KE2 RSKSERPPTILMTEEPSSPKGAVRSPPVDCPRKDTKAAEHNGNSERIEEIKTPDSFEESQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSKSERPPTILMTEEPSSPKGAVRSPPVDCPRKDTKAAEHNGNSERIEEIKTPDSFEESQ
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170
pF1KE2 GEEIGKVERSDSKSSPQAGRRYGVQVMGSGLLAEMKAKQE--------------------
::::::::::::::::::::::::::::::::::::::::
XP_016 GEEIGKVERSDSKSSPQAGRRYGVQVMGSGLLAEMKAKQEKRAACAQKKLGNDAVSQDSS
1150 1160 1170 1180 1190 1200
1180 1190 1200 1210
pF1KE2 -------------------NRFGLGTPEKNTKAEPKAEAGSRSRSSSSTPTSPKPLLQSP
:::::::::::::::::::::::::::::::::::::::::
XP_016 SPALSGVERSDGGGAGLPENRFGLGTPEKNTKAEPKAEAGSRSRSSSSTPTSPKPLLQSP
1210 1220 1230 1240 1250 1260
1220 1230 1240 1250 1260 1270
pF1KE2 KPSLAARPVIPQKPRTASRPDDIPDSPSSPKVALLPPVLKKVPSDKERDGQSSPQPSPRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPSLAARPVIPQKPRTASRPDDIPDSPSSPKVALLPPVLKKVPSDKERDGQSSPQPSPRT
1270 1280 1290 1300 1310 1320
1280 1290 1300 1310 1320
pF1KE2 FSQEVSRRSWGQQAQEYQEQKQRSSSKDGHQGSKSNDSGEEAEKEFIFV
::::: .: :. ...... . . :. :...:: .. : :
XP_016 FSQEVVQR--GDYYKRHSDHDSGKPSSRGKRSSKLYSTIAEEEVNAIGHRKSQPTNVSRR
1330 1340 1350 1360 1370
XP_016 SWGQQAQEYQEQKQRSSSKDGHQGSKSNDSGEEAEKEFIFV
1380 1390 1400 1410
>>XP_016866505 (OMIM: 609593) PREDICTED: F-actin-uncappi (1375 aa)
initn: 7581 init1: 4576 opt: 7601 Z-score: 4580.1 bits: 859.8 E(85289): 0
Smith-Waterman score: 8385; 96.4% identity (96.4% similar) in 1362 aa overlap (1-1313:1-1362)
10 20 30 40 50 60
pF1KE2 MTEESSDVPRELIESIKDVIGRKIKISVKKKVKLEVKGDKVENKVLVLTSCRAFLVTARI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTEESSDVPRELIESIKDVIGRKIKISVKKKVKLEVKGDKVENKVLVLTSCRAFLVTARI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PTKLELTFSYLEIHGVVCSKSAQMIVETEKCSISMKMASPEDVSEVLAHIGTCLRKIFPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTKLELTFSYLEIHGVVCSKSAQMIVETEKCSISMKMASPEDVSEVLAHIGTCLRKIFPG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 LSPVRIMKKVSMEPSERLASLQALWDSQTVAEQGPCGGFSQMYACVCDWLGFSYREEVQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSPVRIMKKVSMEPSERLASLQALWDSQTVAEQGPCGGFSQMYACVCDWLGFSYREEVQW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 DVDTIYLTQDTRELNLQDFSHLDHRDLIPIIAALEYNQWFTKLSSKDLKLSTDVCEQILR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVDTIYLTQDTRELNLQDFSHLDHRDLIPIIAALEYNQWFTKLSSKDLKLSTDVCEQILR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VVSRSNRLEELVLENAGLRTDFAQKLASALAHNPNSGLHTINLAGNPLEDRGVSSLSIQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVSRSNRLEELVLENAGLRTDFAQKLASALAHNPNSGLHTINLAGNPLEDRGVSSLSIQF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 AKLPKGLKHLNLSKTSLSPKGVNSLSQSLSANPLTASTLVHLDLSGNVLRGDDLSHMYNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKLPKGLKHLNLSKTSLSPKGVNSLSQSLSANPLTASTLVHLDLSGNVLRGDDLSHMYNF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 LAQPNAIVHLDLSNTECSLDMVCGALLRGCLQYLAVLNLSRTVFSHRKGKEVPPSFKQFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAQPNAIVHLDLSNTECSLDMVCGALLRGCLQYLAVLNLSRTVFSHRKGKEVPPSFKQFF
370 380 390 400 410 420
430 440 450 460 470
pF1KE2 SSSLALMHINLSGTKLSPEPLKALLLGLACNHNLKGVSLDLSNCEL----RSGGAQVLEG
:::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_016 SSSLALMHINLSGTKLSPEPLKALLLGLACNHNLKGVSLDLSNCELGHCLRSGGAQVLEG
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE2 CIAEIHNITSLDISDNGLESDLSTLIVWLSKNRSIQHLALGKNFNNMKSKNLTPVLDNLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CIAEIHNITSLDISDNGLESDLSTLIVWLSKNRSIQHLALGKNFNNMKSKNLTPVLDNLV
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE2 QMIQDEESPLQSLSLADSKLKTEVTIIINALGSNTSLTKVDISGNGMGDMGAKMLAKALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QMIQDEESPLQSLSLADSKLKTEVTIIINALGSNTSLTKVDISGNGMGDMGAKMLAKALQ
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE2 INTKLRTVIWDKNNITAQGFQDIAVAMEKNYTLRFMPIPMYDASQALKTNPEKTEDALQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INTKLRTVIWDKNNITAQGFQDIAVAMEKNYTLRFMPIPMYDASQALKTNPEKTEDALQK
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE2 IENYLLRNHETRKYLQEQAYRLQQGIVTSTTQQMIDRICVKVQDHLNSLRNCGGDAIQED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IENYLLRNHETRKYLQEQAYRLQQGIVTSTTQQMIDRICVKVQDHLNSLRNCGGDAIQED
670 680 690 700 710 720
720 730 740 750 760 770
pF1KE2 LKSAERLMRDAKNSKTLLPNLYHVGGASWAGASGLLSSPIQETLESMAGEVTRVVDEQLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKSAERLMRDAKNSKTLLPNLYHVGGASWAGASGLLSSPIQETLESMAGEVTRVVDEQLK
730 740 750 760 770 780
780 790 800 810 820 830
pF1KE2 ALLESMVDAAENLCPNVMKKAHIRQDLIHASTEKISIPRTFVKNVLLEQSGIDILNKISE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALLESMVDAAENLCPNVMKKAHIRQDLIHASTEKISIPRTFVKNVLLEQSGIDILNKISE
790 800 810 820 830 840
840 850 860 870 880 890
pF1KE2 VKLTVASFLSDRIVDEILDALSHCHHKLADHFSRRGKTLPQQESLEIELAEEKPVKRSII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKLTVASFLSDRIVDEILDALSHCHHKLADHFSRRGKTLPQQESLEIELAEEKPVKRSII
850 860 870 880 890 900
900 910 920 930 940 950
pF1KE2 TVEELTEIERLEDLDTCMMTPKSKRKSIHSRMLRPVSRAFEMEFDLDKALEEVPIHIEDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVEELTEIERLEDLDTCMMTPKSKRKSIHSRMLRPVSRAFEMEFDLDKALEEVPIHIEDP
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KE2 PFPSLRQEKRSSGFISELPSEEGKKLEHFTKLRPKRNKKQQPTQAAVCAANIVSQDGEQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFPSLRQEKRSSGFISELPSEEGKKLEHFTKLRPKRNKKQQPTQAAVCAANIVSQDGEQN
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KE2 GLMGRVDEGVDEFFTKKVTKMDSKKWSTRGSESHELNEGGDEKKKRDSRKSSGFLNLIKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLMGRVDEGVDEFFTKKVTKMDSKKWSTRGSESHELNEGGDEKKKRDSRKSSGFLNLIKS
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KE2 RSKSERPPTILMTEEPSSPKGAVRSPPVDCPRKDTKAAEHNGNSERIEEIKTPDSFEESQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSKSERPPTILMTEEPSSPKGAVRSPPVDCPRKDTKAAEHNGNSERIEEIKTPDSFEESQ
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170
pF1KE2 GEEIGKVERSDSKSSPQAGRRYGVQVMGSGLLAEMKAKQE--------------------
::::::::::::::::::::::::::::::::::::::::
XP_016 GEEIGKVERSDSKSSPQAGRRYGVQVMGSGLLAEMKAKQEKRAACAQKKLGNDAVSQDSS
1150 1160 1170 1180 1190 1200
1180 1190 1200 1210
pF1KE2 -------------------------NRFGLGTPEKNTKAEPKAEAGSRSRSSSSTPTSPK
:::::::::::::::::::::::::::::::::::
XP_016 SPALSGVERSDGGGAVPKLHPGLPENRFGLGTPEKNTKAEPKAEAGSRSRSSSSTPTSPK
1210 1220 1230 1240 1250 1260
1220 1230 1240 1250 1260 1270
pF1KE2 PLLQSPKPSLAARPVIPQKPRTASRPDDIPDSPSSPKVALLPPVLKKVPSDKERDGQSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLLQSPKPSLAARPVIPQKPRTASRPDDIPDSPSSPKVALLPPVLKKVPSDKERDGQSSP
1270 1280 1290 1300 1310 1320
1280 1290 1300 1310 1320
pF1KE2 QPSPRTFSQEVSRRSWGQQAQEYQEQKQRSSSKDGHQGSKSNDSGEEAEKEFIFV
::::::::::::::::::::::::::::::::::::::::::
XP_016 QPSPRTFSQEVSRRSWGQQAQEYQEQKQRSSSKDGHQGSKSNDSGEEAEKEFIFV
1330 1340 1350 1360 1370
>>XP_016866500 (OMIM: 609593) PREDICTED: F-actin-uncappi (1425 aa)
initn: 7866 init1: 4576 opt: 7601 Z-score: 4579.9 bits: 859.9 E(85289): 0
Smith-Waterman score: 8195; 94.6% identity (95.7% similar) in 1362 aa overlap (1-1313:1-1357)
10 20 30 40 50 60
pF1KE2 MTEESSDVPRELIESIKDVIGRKIKISVKKKVKLEVKGDKVENKVLVLTSCRAFLVTARI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTEESSDVPRELIESIKDVIGRKIKISVKKKVKLEVKGDKVENKVLVLTSCRAFLVTARI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PTKLELTFSYLEIHGVVCSKSAQMIVETEKCSISMKMASPEDVSEVLAHIGTCLRKIFPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTKLELTFSYLEIHGVVCSKSAQMIVETEKCSISMKMASPEDVSEVLAHIGTCLRKIFPG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 LSPVRIMKKVSMEPSERLASLQALWDSQTVAEQGPCGGFSQMYACVCDWLGFSYREEVQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSPVRIMKKVSMEPSERLASLQALWDSQTVAEQGPCGGFSQMYACVCDWLGFSYREEVQW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 DVDTIYLTQDTRELNLQDFSHLDHRDLIPIIAALEYNQWFTKLSSKDLKLSTDVCEQILR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVDTIYLTQDTRELNLQDFSHLDHRDLIPIIAALEYNQWFTKLSSKDLKLSTDVCEQILR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VVSRSNRLEELVLENAGLRTDFAQKLASALAHNPNSGLHTINLAGNPLEDRGVSSLSIQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVSRSNRLEELVLENAGLRTDFAQKLASALAHNPNSGLHTINLAGNPLEDRGVSSLSIQF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 AKLPKGLKHLNLSKTSLSPKGVNSLSQSLSANPLTASTLVHLDLSGNVLRGDDLSHMYNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKLPKGLKHLNLSKTSLSPKGVNSLSQSLSANPLTASTLVHLDLSGNVLRGDDLSHMYNF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 LAQPNAIVHLDLSNTECSLDMVCGALLRGCLQYLAVLNLSRTVFSHRKGKEVPPSFKQFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAQPNAIVHLDLSNTECSLDMVCGALLRGCLQYLAVLNLSRTVFSHRKGKEVPPSFKQFF
370 380 390 400 410 420
430 440 450 460 470
pF1KE2 SSSLALMHINLSGTKLSPEPLKALLLGLACNHNLKGVSLDLSNCEL----RSGGAQVLEG
:::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_016 SSSLALMHINLSGTKLSPEPLKALLLGLACNHNLKGVSLDLSNCELGHCLRSGGAQVLEG
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE2 CIAEIHNITSLDISDNGLESDLSTLIVWLSKNRSIQHLALGKNFNNMKSKNLTPVLDNLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CIAEIHNITSLDISDNGLESDLSTLIVWLSKNRSIQHLALGKNFNNMKSKNLTPVLDNLV
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE2 QMIQDEESPLQSLSLADSKLKTEVTIIINALGSNTSLTKVDISGNGMGDMGAKMLAKALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QMIQDEESPLQSLSLADSKLKTEVTIIINALGSNTSLTKVDISGNGMGDMGAKMLAKALQ
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE2 INTKLRTVIWDKNNITAQGFQDIAVAMEKNYTLRFMPIPMYDASQALKTNPEKTEDALQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INTKLRTVIWDKNNITAQGFQDIAVAMEKNYTLRFMPIPMYDASQALKTNPEKTEDALQK
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE2 IENYLLRNHETRKYLQEQAYRLQQGIVTSTTQQMIDRICVKVQDHLNSLRNCGGDAIQED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IENYLLRNHETRKYLQEQAYRLQQGIVTSTTQQMIDRICVKVQDHLNSLRNCGGDAIQED
670 680 690 700 710 720
720 730 740 750 760 770
pF1KE2 LKSAERLMRDAKNSKTLLPNLYHVGGASWAGASGLLSSPIQETLESMAGEVTRVVDEQLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKSAERLMRDAKNSKTLLPNLYHVGGASWAGASGLLSSPIQETLESMAGEVTRVVDEQLK
730 740 750 760 770 780
780 790 800 810 820 830
pF1KE2 ALLESMVDAAENLCPNVMKKAHIRQDLIHASTEKISIPRTFVKNVLLEQSGIDILNKISE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALLESMVDAAENLCPNVMKKAHIRQDLIHASTEKISIPRTFVKNVLLEQSGIDILNKISE
790 800 810 820 830 840
840 850 860 870 880 890
pF1KE2 VKLTVASFLSDRIVDEILDALSHCHHKLADHFSRRGKTLPQQESLEIELAEEKPVKRSII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKLTVASFLSDRIVDEILDALSHCHHKLADHFSRRGKTLPQQESLEIELAEEKPVKRSII
850 860 870 880 890 900
900 910 920 930 940 950
pF1KE2 TVEELTEIERLEDLDTCMMTPKSKRKSIHSRMLRPVSRAFEMEFDLDKALEEVPIHIEDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVEELTEIERLEDLDTCMMTPKSKRKSIHSRMLRPVSRAFEMEFDLDKALEEVPIHIEDP
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KE2 PFPSLRQEKRSSGFISELPSEEGKKLEHFTKLRPKRNKKQQPTQAAVCAANIVSQDGEQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFPSLRQEKRSSGFISELPSEEGKKLEHFTKLRPKRNKKQQPTQAAVCAANIVSQDGEQN
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KE2 GLMGRVDEGVDEFFTKKVTKMDSKKWSTRGSESHELNEGGDEKKKRDSRKSSGFLNLIKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLMGRVDEGVDEFFTKKVTKMDSKKWSTRGSESHELNEGGDEKKKRDSRKSSGFLNLIKS
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KE2 RSKSERPPTILMTEEPSSPKGAVRSPPVDCPRKDTKAAEHNGNSERIEEIKTPDSFEESQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSKSERPPTILMTEEPSSPKGAVRSPPVDCPRKDTKAAEHNGNSERIEEIKTPDSFEESQ
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170
pF1KE2 GEEIGKVERSDSKSSPQAGRRYGVQVMGSGLLAEMKAKQE--------------------
::::::::::::::::::::::::::::::::::::::::
XP_016 GEEIGKVERSDSKSSPQAGRRYGVQVMGSGLLAEMKAKQEKRAACAQKKLGNDAVSQDSS
1150 1160 1170 1180 1190 1200
1180 1190 1200 1210
pF1KE2 -------------------------NRFGLGTPEKNTKAEPKAEAGSRSRSSSSTPTSPK
:::::::::::::::::::::::::::::::::::
XP_016 SPALSGVERSDGGGAVPKLHPGLPENRFGLGTPEKNTKAEPKAEAGSRSRSSSSTPTSPK
1210 1220 1230 1240 1250 1260
1220 1230 1240 1250 1260 1270
pF1KE2 PLLQSPKPSLAARPVIPQKPRTASRPDDIPDSPSSPKVALLPPVLKKVPSDKERDGQSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLLQSPKPSLAARPVIPQKPRTASRPDDIPDSPSSPKVALLPPVLKKVPSDKERDGQSSP
1270 1280 1290 1300 1310 1320
1280 1290 1300 1310 1320
pF1KE2 QPSPRTFSQEVSRRSWGQQAQEYQEQKQRSSSKDGHQGSKSNDSGEEAEKEFIFV
::::::::::: .:. . :.......:.: . .:..:.
XP_016 QPSPRTFSQEVVQRG-----DYYKRHSDHDSGKPSSRGKRSSKLYSTIAEEEVNAIGHRK
1330 1340 1350 1360 1370
XP_016 SQPTNVSRRSWGQQAQEYQEQKQRSSSKDGHQGSKSNDSGEEAEKEFIFV
1380 1390 1400 1410 1420
>>XP_016866499 (OMIM: 609593) PREDICTED: F-actin-uncappi (1427 aa)
initn: 7861 init1: 5858 opt: 7574 Z-score: 4563.7 bits: 856.9 E(85289): 0
Smith-Waterman score: 8190; 94.5% identity (95.6% similar) in 1363 aa overlap (1-1312:1-1358)
10 20 30 40 50 60
pF1KE2 MTEESSDVPRELIESIKDVIGRKIKISVKKKVKLEVKGDKVENKVLVLTSCRAFLVTARI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTEESSDVPRELIESIKDVIGRKIKISVKKKVKLEVKGDKVENKVLVLTSCRAFLVTARI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PTKLELTFSYLEIHGVVCSKSAQMIVETEKCSISMKMASPEDVSEVLAHIGTCLRKIFPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTKLELTFSYLEIHGVVCSKSAQMIVETEKCSISMKMASPEDVSEVLAHIGTCLRKIFPG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 LSPVRIMKKVSMEPSERLASLQALWDSQTVAEQGPCGGFSQMYACVCDWLGFSYREEVQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSPVRIMKKVSMEPSERLASLQALWDSQTVAEQGPCGGFSQMYACVCDWLGFSYREEVQW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 DVDTIYLTQDTRELNLQDFSHLDHRDLIPIIAALEYNQWFTKLSSKDLKLSTDVCEQILR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVDTIYLTQDTRELNLQDFSHLDHRDLIPIIAALEYNQWFTKLSSKDLKLSTDVCEQILR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VVSRSNRLEELVLENAGLRTDFAQKLASALAHNPNSGLHTINLAGNPLEDRGVSSLSIQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVSRSNRLEELVLENAGLRTDFAQKLASALAHNPNSGLHTINLAGNPLEDRGVSSLSIQF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 AKLPKGLKHLNLSKTSLSPKGVNSLSQSLSANPLTASTLVHLDLSGNVLRGDDLSHMYNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKLPKGLKHLNLSKTSLSPKGVNSLSQSLSANPLTASTLVHLDLSGNVLRGDDLSHMYNF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 LAQPNAIVHLDLSNTECSLDMVCGALLRGCLQYLAVLNLSRTVFSHRKGKEVPPSFKQFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAQPNAIVHLDLSNTECSLDMVCGALLRGCLQYLAVLNLSRTVFSHRKGKEVPPSFKQFF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 SSSLALMHINLSGTKLSPEPLKALLLGLACNHNLKGVSLDLSNCELRSGGAQVLEGCIAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSSLALMHINLSGTKLSPEPLKALLLGLACNHNLKGVSLDLSNCELRSGGAQVLEGCIAE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 IHNITSLDISDNGLESDLSTLIVWLSKNRSIQHLALGKNFNNMKSKNLTPVLDNLVQMIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IHNITSLDISDNGLESDLSTLIVWLSKNRSIQHLALGKNFNNMKSKNLTPVLDNLVQMIQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 DEESPLQSLSLADSKLKTEVTIIINALGSNTSLTKVDISGNGMGDMGAKMLAKALQINTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEESPLQSLSLADSKLKTEVTIIINALGSNTSLTKVDISGNGMGDMGAKMLAKALQINTK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 LRTVIWDKNNITAQGFQDIAVAMEKNYTLRFMPIPMYDASQALKTNPEKTEDALQKIENY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRTVIWDKNNITAQGFQDIAVAMEKNYTLRFMPIPMYDASQALKTNPEKTEDALQKIENY
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 LLRNHETRKYLQEQAYRLQQGIVTSTTQQMIDRICVKVQDHLNSLRNCGGDAIQEDLKSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLRNHETRKYLQEQAYRLQQGIVTSTTQQMIDRICVKVQDHLNSLRNCGGDAIQEDLKSA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 ERLMRDAKNSKTLLPNLYHVGGASWAGASGLLSSPIQETLESMAGEVTRVVDEQLKALLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERLMRDAKNSKTLLPNLYHVGGASWAGASGLLSSPIQETLESMAGEVTRVVDEQLKALLE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 SMVDAAENLCPNVMKKAHIRQDLIHASTEKISIPRTFVKNVLLEQSGIDILNKISEVKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SMVDAAENLCPNVMKKAHIRQDLIHASTEKISIPRTFVKNVLLEQSGIDILNKISEVKLT
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 VASFLSDRIVDEILDALSHCHHKLADHFSRRGKTLPQQESLEIELAEEKPVKRSIITVEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VASFLSDRIVDEILDALSHCHHKLADHFSRRGKTLPQQESLEIELAEEKPVKRSIITVEE
850 860 870 880 890 900
910 920 930 940 950
pF1KE2 LTEIERLEDLDTCM------MTPKSKRKSIHSRMLRPVSRAFEMEFDLDKALEEVPIHIE
:::::::::::::: ::::::::::::::::::::::::::::::::::::::::
XP_016 LTEIERLEDLDTCMTLCCTSMTPKSKRKSIHSRMLRPVSRAFEMEFDLDKALEEVPIHIE
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KE2 DPPFPSLRQEKRSSGFISELPSEEGKKLEHFTKLRPKRNKKQQPTQAAVCAANIVSQDGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPPFPSLRQEKRSSGFISELPSEEGKKLEHFTKLRPKRNKKQQPTQAAVCAANIVSQDGE
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KE2 QNGLMGRVDEGVDEFFTKKVTKMDSKKWSTRGSESHELNEGGDEKKKRDSRKSSGFLNLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNGLMGRVDEGVDEFFTKKVTKMDSKKWSTRGSESHELNEGGDEKKKRDSRKSSGFLNLI
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KE2 KSRSKSERPPTILMTEEPSSPKGAVRSPPVDCPRKDTKAAEHNGNSERIEEIKTPDSFEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSRSKSERPPTILMTEEPSSPKGAVRSPPVDCPRKDTKAAEHNGNSERIEEIKTPDSFEE
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170
pF1KE2 SQGEEIGKVERSDSKSSPQAGRRYGVQVMGSGLLAEMKAKQE------------------
::::::::::::::::::::::::::::::::::::::::::
XP_016 SQGEEIGKVERSDSKSSPQAGRRYGVQVMGSGLLAEMKAKQEKRAACAQKKLGNDAVSQD
1150 1160 1170 1180 1190 1200
1180 1190 1200
pF1KE2 ---------------------------NRFGLGTPEKNTKAEPKAEAGSRSRSSSSTPTS
:::::::::::::::::::::::::::::::::
XP_016 SSSPALSGVERSDGGGAVPKLHPGLPENRFGLGTPEKNTKAEPKAEAGSRSRSSSSTPTS
1210 1220 1230 1240 1250 1260
1210 1220 1230 1240 1250 1260
pF1KE2 PKPLLQSPKPSLAARPVIPQKPRTASRPDDIPDSPSSPKVALLPPVLKKVPSDKERDGQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKPLLQSPKPSLAARPVIPQKPRTASRPDDIPDSPSSPKVALLPPVLKKVPSDKERDGQS
1270 1280 1290 1300 1310 1320
1270 1280 1290 1300 1310 1320
pF1KE2 SPQPSPRTFSQEVSRRSWGQQAQEYQEQKQRSSSKDGHQGSKSNDSGEEAEKEFIFV
::::::::::::: .:. . :.......:.: . .:..:
XP_016 SPQPSPRTFSQEVVQRG-----DYYKRHSDHDSGKPSSRGKRSSKLYSTIAEEEVNAIGH
1330 1340 1350 1360 1370
XP_016 RKSQPTNVSRRSWGQQAQEYQEQKQRSSSKDGHQGSKSNDSGEEAEKEFIFV
1380 1390 1400 1410 1420
>>XP_016866503 (OMIM: 609593) PREDICTED: F-actin-uncappi (1411 aa)
initn: 5316 init1: 2844 opt: 7055 Z-score: 4252.0 bits: 799.2 E(85289): 0
Smith-Waterman score: 7995; 92.8% identity (93.9% similar) in 1367 aa overlap (1-1312:1-1342)
10 20 30 40 50 60
pF1KE2 MTEESSDVPRELIESIKDVIGRKIKISVKKKVKLEVKGDKVENKVLVLTSCRAFLVTARI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTEESSDVPRELIESIKDVIGRKIKISVKKKVKLEVKGDKVENKVLVLTSCRAFLVTARI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PTKLELTFSYLEIHGVVCSKSAQMIVETEKCSISMKMASPEDVSEVLAHIGTCLRKIFPG
::: :::::::::::::::::::::::::::::::::::::
XP_016 PTK--------------------MIVETEKCSISMKMASPEDVSEVLAHIGTCLRKIFPG
70 80 90 100
130 140 150 160 170 180
pF1KE2 LSPVRIMKKVSMEPSERLASLQALWDSQTVAEQGPCGGFSQMYACVCDWLGFSYREEVQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSPVRIMKKVSMEPSERLASLQALWDSQTVAEQGPCGGFSQMYACVCDWLGFSYREEVQW
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE2 DVDTIYLTQDTRELNLQDFSHLDHRDLIPIIAALEYNQWFTKLSSKDLKLSTDVCEQILR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVDTIYLTQDTRELNLQDFSHLDHRDLIPIIAALEYNQWFTKLSSKDLKLSTDVCEQILR
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE2 VVSRSNRLEELVLENAGLRTDFAQKLASALAHNPNSGLHTINLAGNPLEDRGVSSLSIQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVSRSNRLEELVLENAGLRTDFAQKLASALAHNPNSGLHTINLAGNPLEDRGVSSLSIQF
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE2 AKLPKGLKHLNLSKTSLSPKGVNSLSQSLSANPLTASTLVHLDLSGNVLRGDDLSHMYNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKLPKGLKHLNLSKTSLSPKGVNSLSQSLSANPLTASTLVHLDLSGNVLRGDDLSHMYNF
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE2 LAQPNAIVHLDLSNTECSLDMVCGALLRGCLQYLAVLNLSRTVFSHRKGKEVPPSFKQFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAQPNAIVHLDLSNTECSLDMVCGALLRGCLQYLAVLNLSRTVFSHRKGKEVPPSFKQFF
350 360 370 380 390 400
430 440 450 460 470
pF1KE2 SSSLALMHINLSGTKLSPEPLKALLLGLACNHNLKGVSLDLSNCEL----RSGGAQVLEG
:::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_016 SSSLALMHINLSGTKLSPEPLKALLLGLACNHNLKGVSLDLSNCELGHCLRSGGAQVLEG
410 420 430 440 450 460
480 490 500 510 520 530
pF1KE2 CIAEIHNITSLDISDNGLESDLSTLIVWLSKNRSIQHLALGKNFNNMKSKNLTPVLDNLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CIAEIHNITSLDISDNGLESDLSTLIVWLSKNRSIQHLALGKNFNNMKSKNLTPVLDNLV
470 480 490 500 510 520
540 550 560 570 580 590
pF1KE2 QMIQDEESPLQSLSLADSKLKTEVTIIINALGSNTSLTKVDISGNGMGDMGAKMLAKALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QMIQDEESPLQSLSLADSKLKTEVTIIINALGSNTSLTKVDISGNGMGDMGAKMLAKALQ
530 540 550 560 570 580
600 610 620 630 640 650
pF1KE2 INTKLRTVIWDKNNITAQGFQDIAVAMEKNYTLRFMPIPMYDASQALKTNPEKTEDALQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INTKLRTVIWDKNNITAQGFQDIAVAMEKNYTLRFMPIPMYDASQALKTNPEKTEDALQK
590 600 610 620 630 640
660 670 680 690 700 710
pF1KE2 IENYLLRNHETRKYLQEQAYRLQQGIVTSTTQQMIDRICVKVQDHLNSLRNCGGDAIQED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IENYLLRNHETRKYLQEQAYRLQQGIVTSTTQQMIDRICVKVQDHLNSLRNCGGDAIQED
650 660 670 680 690 700
720 730 740 750 760 770
pF1KE2 LKSAERLMRDAKNSKTLLPNLYHVGGASWAGASGLLSSPIQETLESMAGEVTRVVDEQLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKSAERLMRDAKNSKTLLPNLYHVGGASWAGASGLLSSPIQETLESMAGEVTRVVDEQLK
710 720 730 740 750 760
780 790 800 810 820 830
pF1KE2 ALLESMVDAAENLCPNVMKKAHIRQDLIHASTEKISIPRTFVKNVLLEQSGIDILNKISE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALLESMVDAAENLCPNVMKKAHIRQDLIHASTEKISIPRTFVKNVLLEQSGIDILNKISE
770 780 790 800 810 820
840 850 860 870 880 890
pF1KE2 VKLTVASFLSDRIVDEILDALSHCHHKLADHFSRRGKTLPQQESLEIELAEEKPVKRSII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKLTVASFLSDRIVDEILDALSHCHHKLADHFSRRGKTLPQQESLEIELAEEKPVKRSII
830 840 850 860 870 880
900 910 920 930 940 950
pF1KE2 TVEELTEIERLEDLDTCM------MTPKSKRKSIHSRMLRPVSRAFEMEFDLDKALEEVP
:::::::::::::::::: ::::::::::::::::::::::::::::::::::::
XP_016 TVEELTEIERLEDLDTCMTLCCTSMTPKSKRKSIHSRMLRPVSRAFEMEFDLDKALEEVP
890 900 910 920 930 940
960 970 980 990 1000 1010
pF1KE2 IHIEDPPFPSLRQEKRSSGFISELPSEEGKKLEHFTKLRPKRNKKQQPTQAAVCAANIVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IHIEDPPFPSLRQEKRSSGFISELPSEEGKKLEHFTKLRPKRNKKQQPTQAAVCAANIVS
950 960 970 980 990 1000
1020 1030 1040 1050 1060 1070
pF1KE2 QDGEQNGLMGRVDEGVDEFFTKKVTKMDSKKWSTRGSESHELNEGGDEKKKRDSRKSSGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDGEQNGLMGRVDEGVDEFFTKKVTKMDSKKWSTRGSESHELNEGGDEKKKRDSRKSSGF
1010 1020 1030 1040 1050 1060
1080 1090 1100 1110 1120 1130
pF1KE2 LNLIKSRSKSERPPTILMTEEPSSPKGAVRSPPVDCPRKDTKAAEHNGNSERIEEIKTPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNLIKSRSKSERPPTILMTEEPSSPKGAVRSPPVDCPRKDTKAAEHNGNSERIEEIKTPD
1070 1080 1090 1100 1110 1120
1140 1150 1160 1170
pF1KE2 SFEESQGEEIGKVERSDSKSSPQAGRRYGVQVMGSGLLAEMKAKQE--------------
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFEESQGEEIGKVERSDSKSSPQAGRRYGVQVMGSGLLAEMKAKQEKRAACAQKKLGNDA
1130 1140 1150 1160 1170 1180
1180 1190 1200
pF1KE2 -------------------------------NRFGLGTPEKNTKAEPKAEAGSRSRSSSS
:::::::::::::::::::::::::::::
XP_016 VSQDSSSPALSGVERSDGGGAVPKLHPGLPENRFGLGTPEKNTKAEPKAEAGSRSRSSSS
1190 1200 1210 1220 1230 1240
1210 1220 1230 1240 1250 1260
pF1KE2 TPTSPKPLLQSPKPSLAARPVIPQKPRTASRPDDIPDSPSSPKVALLPPVLKKVPSDKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPTSPKPLLQSPKPSLAARPVIPQKPRTASRPDDIPDSPSSPKVALLPPVLKKVPSDKER
1250 1260 1270 1280 1290 1300
1270 1280 1290 1300 1310 1320
pF1KE2 DGQSSPQPSPRTFSQEVSRRSWGQQAQEYQEQKQRSSSKDGHQGSKSNDSGEEAEKEFIF
::::::::::::::::: .:. . :.......:.: . .:..:
XP_016 DGQSSPQPSPRTFSQEVVQRG-----DYYKRHSDHDSGKPSSRGKRSSKLYSTIAEEEVN
1310 1320 1330 1340 1350
pF1KE2 V
XP_016 AIGHRKSQPTNVSRRSWGQQAQEYQEQKQRSSSKDGHQGSKSNDSGEEAEKEFIFV
1360 1370 1380 1390 1400 1410
>>XP_016866506 (OMIM: 609593) PREDICTED: F-actin-uncappi (944 aa)
initn: 3019 init1: 3019 opt: 5840 Z-score: 3524.7 bits: 664.0 E(85289): 1.4e-189
Smith-Waterman score: 5840; 99.6% identity (99.6% similar) in 918 aa overlap (1-914:1-918)
10 20 30 40 50 60
pF1KE2 MTEESSDVPRELIESIKDVIGRKIKISVKKKVKLEVKGDKVENKVLVLTSCRAFLVTARI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTEESSDVPRELIESIKDVIGRKIKISVKKKVKLEVKGDKVENKVLVLTSCRAFLVTARI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PTKLELTFSYLEIHGVVCSKSAQMIVETEKCSISMKMASPEDVSEVLAHIGTCLRKIFPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTKLELTFSYLEIHGVVCSKSAQMIVETEKCSISMKMASPEDVSEVLAHIGTCLRKIFPG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 LSPVRIMKKVSMEPSERLASLQALWDSQTVAEQGPCGGFSQMYACVCDWLGFSYREEVQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSPVRIMKKVSMEPSERLASLQALWDSQTVAEQGPCGGFSQMYACVCDWLGFSYREEVQW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 DVDTIYLTQDTRELNLQDFSHLDHRDLIPIIAALEYNQWFTKLSSKDLKLSTDVCEQILR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVDTIYLTQDTRELNLQDFSHLDHRDLIPIIAALEYNQWFTKLSSKDLKLSTDVCEQILR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VVSRSNRLEELVLENAGLRTDFAQKLASALAHNPNSGLHTINLAGNPLEDRGVSSLSIQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVSRSNRLEELVLENAGLRTDFAQKLASALAHNPNSGLHTINLAGNPLEDRGVSSLSIQF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 AKLPKGLKHLNLSKTSLSPKGVNSLSQSLSANPLTASTLVHLDLSGNVLRGDDLSHMYNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKLPKGLKHLNLSKTSLSPKGVNSLSQSLSANPLTASTLVHLDLSGNVLRGDDLSHMYNF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 LAQPNAIVHLDLSNTECSLDMVCGALLRGCLQYLAVLNLSRTVFSHRKGKEVPPSFKQFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAQPNAIVHLDLSNTECSLDMVCGALLRGCLQYLAVLNLSRTVFSHRKGKEVPPSFKQFF
370 380 390 400 410 420
430 440 450 460 470
pF1KE2 SSSLALMHINLSGTKLSPEPLKALLLGLACNHNLKGVSLDLSNCEL----RSGGAQVLEG
:::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_016 SSSLALMHINLSGTKLSPEPLKALLLGLACNHNLKGVSLDLSNCELGHCLRSGGAQVLEG
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE2 CIAEIHNITSLDISDNGLESDLSTLIVWLSKNRSIQHLALGKNFNNMKSKNLTPVLDNLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CIAEIHNITSLDISDNGLESDLSTLIVWLSKNRSIQHLALGKNFNNMKSKNLTPVLDNLV
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE2 QMIQDEESPLQSLSLADSKLKTEVTIIINALGSNTSLTKVDISGNGMGDMGAKMLAKALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QMIQDEESPLQSLSLADSKLKTEVTIIINALGSNTSLTKVDISGNGMGDMGAKMLAKALQ
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE2 INTKLRTVIWDKNNITAQGFQDIAVAMEKNYTLRFMPIPMYDASQALKTNPEKTEDALQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INTKLRTVIWDKNNITAQGFQDIAVAMEKNYTLRFMPIPMYDASQALKTNPEKTEDALQK
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE2 IENYLLRNHETRKYLQEQAYRLQQGIVTSTTQQMIDRICVKVQDHLNSLRNCGGDAIQED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IENYLLRNHETRKYLQEQAYRLQQGIVTSTTQQMIDRICVKVQDHLNSLRNCGGDAIQED
670 680 690 700 710 720
720 730 740 750 760 770
pF1KE2 LKSAERLMRDAKNSKTLLPNLYHVGGASWAGASGLLSSPIQETLESMAGEVTRVVDEQLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKSAERLMRDAKNSKTLLPNLYHVGGASWAGASGLLSSPIQETLESMAGEVTRVVDEQLK
730 740 750 760 770 780
780 790 800 810 820 830
pF1KE2 ALLESMVDAAENLCPNVMKKAHIRQDLIHASTEKISIPRTFVKNVLLEQSGIDILNKISE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALLESMVDAAENLCPNVMKKAHIRQDLIHASTEKISIPRTFVKNVLLEQSGIDILNKISE
790 800 810 820 830 840
840 850 860 870 880 890
pF1KE2 VKLTVASFLSDRIVDEILDALSHCHHKLADHFSRRGKTLPQQESLEIELAEEKPVKRSII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKLTVASFLSDRIVDEILDALSHCHHKLADHFSRRGKTLPQQESLEIELAEEKPVKRSII
850 860 870 880 890 900
900 910 920 930 940 950
pF1KE2 TVEELTEIERLEDLDTCMMTPKSKRKSIHSRMLRPVSRAFEMEFDLDKALEEVPIHIEDP
::::::::::::::::::
XP_016 TVEELTEIERLEDLDTCMTLCCTSILNEIGNNLETRLDFARWFS
910 920 930 940
>>XP_016866504 (OMIM: 609593) PREDICTED: F-actin-uncappi (1381 aa)
initn: 4737 init1: 3019 opt: 5840 Z-score: 3522.2 bits: 664.1 E(85289): 1.9e-189
Smith-Waterman score: 8293; 95.9% identity (95.9% similar) in 1358 aa overlap (1-1303:1-1358)
10 20 30 40 50 60
pF1KE2 MTEESSDVPRELIESIKDVIGRKIKISVKKKVKLEVKGDKVENKVLVLTSCRAFLVTARI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTEESSDVPRELIESIKDVIGRKIKISVKKKVKLEVKGDKVENKVLVLTSCRAFLVTARI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PTKLELTFSYLEIHGVVCSKSAQMIVETEKCSISMKMASPEDVSEVLAHIGTCLRKIFPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTKLELTFSYLEIHGVVCSKSAQMIVETEKCSISMKMASPEDVSEVLAHIGTCLRKIFPG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 LSPVRIMKKVSMEPSERLASLQALWDSQTVAEQGPCGGFSQMYACVCDWLGFSYREEVQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSPVRIMKKVSMEPSERLASLQALWDSQTVAEQGPCGGFSQMYACVCDWLGFSYREEVQW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 DVDTIYLTQDTRELNLQDFSHLDHRDLIPIIAALEYNQWFTKLSSKDLKLSTDVCEQILR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVDTIYLTQDTRELNLQDFSHLDHRDLIPIIAALEYNQWFTKLSSKDLKLSTDVCEQILR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VVSRSNRLEELVLENAGLRTDFAQKLASALAHNPNSGLHTINLAGNPLEDRGVSSLSIQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVSRSNRLEELVLENAGLRTDFAQKLASALAHNPNSGLHTINLAGNPLEDRGVSSLSIQF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 AKLPKGLKHLNLSKTSLSPKGVNSLSQSLSANPLTASTLVHLDLSGNVLRGDDLSHMYNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKLPKGLKHLNLSKTSLSPKGVNSLSQSLSANPLTASTLVHLDLSGNVLRGDDLSHMYNF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 LAQPNAIVHLDLSNTECSLDMVCGALLRGCLQYLAVLNLSRTVFSHRKGKEVPPSFKQFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAQPNAIVHLDLSNTECSLDMVCGALLRGCLQYLAVLNLSRTVFSHRKGKEVPPSFKQFF
370 380 390 400 410 420
430 440 450 460 470
pF1KE2 SSSLALMHINLSGTKLSPEPLKALLLGLACNHNLKGVSLDLSNCEL----RSGGAQVLEG
:::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
XP_016 SSSLALMHINLSGTKLSPEPLKALLLGLACNHNLKGVSLDLSNCELGHCLRSGGAQVLEG
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE2 CIAEIHNITSLDISDNGLESDLSTLIVWLSKNRSIQHLALGKNFNNMKSKNLTPVLDNLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CIAEIHNITSLDISDNGLESDLSTLIVWLSKNRSIQHLALGKNFNNMKSKNLTPVLDNLV
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE2 QMIQDEESPLQSLSLADSKLKTEVTIIINALGSNTSLTKVDISGNGMGDMGAKMLAKALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QMIQDEESPLQSLSLADSKLKTEVTIIINALGSNTSLTKVDISGNGMGDMGAKMLAKALQ
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE2 INTKLRTVIWDKNNITAQGFQDIAVAMEKNYTLRFMPIPMYDASQALKTNPEKTEDALQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INTKLRTVIWDKNNITAQGFQDIAVAMEKNYTLRFMPIPMYDASQALKTNPEKTEDALQK
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE2 IENYLLRNHETRKYLQEQAYRLQQGIVTSTTQQMIDRICVKVQDHLNSLRNCGGDAIQED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IENYLLRNHETRKYLQEQAYRLQQGIVTSTTQQMIDRICVKVQDHLNSLRNCGGDAIQED
670 680 690 700 710 720
720 730 740 750 760 770
pF1KE2 LKSAERLMRDAKNSKTLLPNLYHVGGASWAGASGLLSSPIQETLESMAGEVTRVVDEQLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKSAERLMRDAKNSKTLLPNLYHVGGASWAGASGLLSSPIQETLESMAGEVTRVVDEQLK
730 740 750 760 770 780
780 790 800 810 820 830
pF1KE2 ALLESMVDAAENLCPNVMKKAHIRQDLIHASTEKISIPRTFVKNVLLEQSGIDILNKISE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALLESMVDAAENLCPNVMKKAHIRQDLIHASTEKISIPRTFVKNVLLEQSGIDILNKISE
790 800 810 820 830 840
840 850 860 870 880 890
pF1KE2 VKLTVASFLSDRIVDEILDALSHCHHKLADHFSRRGKTLPQQESLEIELAEEKPVKRSII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKLTVASFLSDRIVDEILDALSHCHHKLADHFSRRGKTLPQQESLEIELAEEKPVKRSII
850 860 870 880 890 900
900 910 920 930 940 950
pF1KE2 TVEELTEIERLEDLDTCM------MTPKSKRKSIHSRMLRPVSRAFEMEFDLDKALEEVP
:::::::::::::::::: ::::::::::::::::::::::::::::::::::::
XP_016 TVEELTEIERLEDLDTCMTLCCTSMTPKSKRKSIHSRMLRPVSRAFEMEFDLDKALEEVP
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KE2 IHIEDPPFPSLRQEKRSSGFISELPSEEGKKLEHFTKLRPKRNKKQQPTQAAVCAANIVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IHIEDPPFPSLRQEKRSSGFISELPSEEGKKLEHFTKLRPKRNKKQQPTQAAVCAANIVS
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KE2 QDGEQNGLMGRVDEGVDEFFTKKVTKMDSKKWSTRGSESHELNEGGDEKKKRDSRKSSGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDGEQNGLMGRVDEGVDEFFTKKVTKMDSKKWSTRGSESHELNEGGDEKKKRDSRKSSGF
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KE2 LNLIKSRSKSERPPTILMTEEPSSPKGAVRSPPVDCPRKDTKAAEHNGNSERIEEIKTPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNLIKSRSKSERPPTILMTEEPSSPKGAVRSPPVDCPRKDTKAAEHNGNSERIEEIKTPD
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170
pF1KE2 SFEESQGEEIGKVERSDSKSSPQAGRRYGVQVMGSGLLAEMKAKQE--------------
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFEESQGEEIGKVERSDSKSSPQAGRRYGVQVMGSGLLAEMKAKQEKRAACAQKKLGNDA
1150 1160 1170 1180 1190 1200
1180 1190 1200
pF1KE2 -------------------------------NRFGLGTPEKNTKAEPKAEAGSRSRSSSS
:::::::::::::::::::::::::::::
XP_016 VSQDSSSPALSGVERSDGGGAVPKLHPGLPENRFGLGTPEKNTKAEPKAEAGSRSRSSSS
1210 1220 1230 1240 1250 1260
1210 1220 1230 1240 1250 1260
pF1KE2 TPTSPKPLLQSPKPSLAARPVIPQKPRTASRPDDIPDSPSSPKVALLPPVLKKVPSDKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPTSPKPLLQSPKPSLAARPVIPQKPRTASRPDDIPDSPSSPKVALLPPVLKKVPSDKER
1270 1280 1290 1300 1310 1320
1270 1280 1290 1300 1310 1320
pF1KE2 DGQSSPQPSPRTFSQEVSRRSWGQQAQEYQEQKQRSSSKDGHQGSKSNDSGEEAEKEFIF
::::::::::::::::::::::::::::::::::::::
XP_016 DGQSSPQPSPRTFSQEVSRRSWGQQAQEYQEQKQRSSSKDGHQGSKSNDSGEEAEKEFIF
1330 1340 1350 1360 1370 1380
pF1KE2 V
XP_016 V
1326 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 21:03:03 2016 done: Wed Nov 2 21:03:06 2016
Total Scan time: 16.320 Total Display time: 0.610
Function used was FASTA [36.3.4 Apr, 2011]