Result of FASTA (omim) for
pFN21AE2545
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2545, 202 aa
1>>>pF1KE2545 202 - 202 aa - 202 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.4837+/-0.000304; mu= -6.0499+/- 0.019
mean_var=173.7882+/-34.683, 0's: 0 Z-trim(122.4): 21 B-trim: 0 in 0/55
Lambda= 0.097289
statistics sampled from 40365 (40386) to 40365 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.796), E-opt: 0.2 (0.474), width: 16
Scan time: 7.310
The best scores are: opt bits E(85289)
NP_001698 (OMIM: 605846) B-cell CLL/lymphoma 7 pro ( 202) 1309 194.7 8.3e-50
NP_001287990 (OMIM: 605846) B-cell CLL/lymphoma 7 ( 213) 1114 167.4 1.5e-41
NP_001184173 (OMIM: 605846) B-cell CLL/lymphoma 7 ( 145) 581 92.5 3.5e-19
NP_004756 (OMIM: 605847) B-cell CLL/lymphoma 7 pro ( 217) 556 89.1 5.8e-18
NP_001273455 (OMIM: 605847) B-cell CLL/lymphoma 7 ( 242) 556 89.1 6.4e-18
XP_011544282 (OMIM: 605847) PREDICTED: B-cell CLL/ ( 293) 551 88.4 1.2e-17
NP_001019979 (OMIM: 601406) B-cell CLL/lymphoma 7 ( 210) 497 80.8 1.8e-15
NP_066273 (OMIM: 601406) B-cell CLL/lymphoma 7 pro ( 231) 495 80.5 2.3e-15
XP_016879377 (OMIM: 605847) PREDICTED: B-cell CLL/ ( 178) 469 76.8 2.3e-14
XP_016879375 (OMIM: 605847) PREDICTED: B-cell CLL/ ( 178) 469 76.8 2.3e-14
XP_016879376 (OMIM: 605847) PREDICTED: B-cell CLL/ ( 178) 469 76.8 2.3e-14
XP_016879374 (OMIM: 605847) PREDICTED: B-cell CLL/ ( 178) 469 76.8 2.3e-14
>>NP_001698 (OMIM: 605846) B-cell CLL/lymphoma 7 protein (202 aa)
initn: 1309 init1: 1309 opt: 1309 Z-score: 1015.2 bits: 194.7 E(85289): 8.3e-50
Smith-Waterman score: 1309; 100.0% identity (100.0% similar) in 202 aa overlap (1-202:1-202)
10 20 30 40 50 60
pF1KE2 MSGRSVRAETRSRAKDDIKKVMAAIEKVRKWEKKWVTVGDTSLRIFKWVPVTDSKEKEKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSGRSVRAETRSRAKDDIKKVMAAIEKVRKWEKKWVTVGDTSLRIFKWVPVTDSKEKEKS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 KSNSSAAREPNGFPSDASANSSLLLEFQDENSNQSSVSDVYQLKVDSSTNSSPSPQQSES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSNSSAAREPNGFPSDASANSSLLLEFQDENSNQSSVSDVYQLKVDSSTNSSPSPQQSES
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 LSPAHTSDFRTDDSQPPTLGQEILEEPSLPSSEVADEPPTLTKEEPVPLETQVVEEEEDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSPAHTSDFRTDDSQPPTLGQEILEEPSLPSSEVADEPPTLTKEEPVPLETQVVEEEEDS
130 140 150 160 170 180
190 200
pF1KE2 GAPPLKRFCVDQPTVPQTASES
::::::::::::::::::::::
NP_001 GAPPLKRFCVDQPTVPQTASES
190 200
>>NP_001287990 (OMIM: 605846) B-cell CLL/lymphoma 7 prot (213 aa)
initn: 1114 init1: 1114 opt: 1114 Z-score: 866.9 bits: 167.4 E(85289): 1.5e-41
Smith-Waterman score: 1114; 100.0% identity (100.0% similar) in 171 aa overlap (32-202:43-213)
10 20 30 40 50 60
pF1KE2 SGRSVRAETRSRAKDDIKKVMAAIEKVRKWEKKWVTVGDTSLRIFKWVPVTDSKEKEKSK
::::::::::::::::::::::::::::::
NP_001 HWRNLGSLQPLPLRFKQFSCLSLLSSWDYREKKWVTVGDTSLRIFKWVPVTDSKEKEKSK
20 30 40 50 60 70
70 80 90 100 110 120
pF1KE2 SNSSAAREPNGFPSDASANSSLLLEFQDENSNQSSVSDVYQLKVDSSTNSSPSPQQSESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNSSAAREPNGFPSDASANSSLLLEFQDENSNQSSVSDVYQLKVDSSTNSSPSPQQSESL
80 90 100 110 120 130
130 140 150 160 170 180
pF1KE2 SPAHTSDFRTDDSQPPTLGQEILEEPSLPSSEVADEPPTLTKEEPVPLETQVVEEEEDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPAHTSDFRTDDSQPPTLGQEILEEPSLPSSEVADEPPTLTKEEPVPLETQVVEEEEDSG
140 150 160 170 180 190
190 200
pF1KE2 APPLKRFCVDQPTVPQTASES
:::::::::::::::::::::
NP_001 APPLKRFCVDQPTVPQTASES
200 210
>>NP_001184173 (OMIM: 605846) B-cell CLL/lymphoma 7 prot (145 aa)
initn: 600 init1: 578 opt: 581 Z-score: 465.3 bits: 92.5 E(85289): 3.5e-19
Smith-Waterman score: 818; 71.8% identity (71.8% similar) in 202 aa overlap (1-202:1-145)
10 20 30 40 50 60
pF1KE2 MSGRSVRAETRSRAKDDIKKVMAAIEKVRKWEKKWVTVGDTSLRIFKWVPVTDSKEKEKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSGRSVRAETRSRAKDDIKKVMAAIEKVRKWEKKWVTVGDTSLRIFKWVPVTDSKEKEKS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 KSNSSAAREPNGFPSDASANSSLLLEFQDENSNQSSVSDVYQLKVDSSTNSSPSPQQSES
::::::::::::::::::::::::::::
NP_001 KSNSSAAREPNGFPSDASANSSLLLEFQ--------------------------------
70 80
130 140 150 160 170 180
pF1KE2 LSPAHTSDFRTDDSQPPTLGQEILEEPSLPSSEVADEPPTLTKEEPVPLETQVVEEEEDS
:::::::::::::::::::::::::::::::::::
NP_001 -------------------------EPSLPSSEVADEPPTLTKEEPVPLETQVVEEEEDS
90 100 110 120
190 200
pF1KE2 GAPPLKRFCVDQPTVPQTASES
::::::::::::::::::::::
NP_001 GAPPLKRFCVDQPTVPQTASES
130 140
>>NP_004756 (OMIM: 605847) B-cell CLL/lymphoma 7 protein (217 aa)
initn: 608 init1: 356 opt: 556 Z-score: 443.5 bits: 89.1 E(85289): 5.8e-18
Smith-Waterman score: 582; 49.1% identity (71.4% similar) in 220 aa overlap (1-193:1-215)
10 20 30 40 50 60
pF1KE2 MSGRSVRAETRSRAKDDIKKVMAAIEKVRKWEKKWVTVGDTSLRIFKWVPVTDSKEKEKS
:.::.::::::::::::::::::.:::::.:::.:::::::::::::::::.: .:.:.
NP_004 MAGRTVRAETRSRAKDDIKKVMATIEKVRRWEKRWVTVGDTSLRIFKWVPVVDPQEEERR
10 20 30 40 50 60
70 80 90 100 110
pF1KE2 KSNSSA----AREPNGFPSDASANSSL-LLEFQDENSNQSSVSDVYQLKVDSSTNSSP--
.....: .:: : .. ... : ::...::::::: :. .....:. ::
NP_004 RAGGGAERSRGRERRGRGASPRGGGPLILLDLNDENSNQSFHSE---GSLQKGTEPSPGG
70 80 90 100 110
120 130 140 150 160 170
pF1KE2 SPQQSESLSPAHTSDFRTDDSQPPTLGQEILEEPSLPSSEVADEPPTLTKEEPVP--LET
.:: :. .::: . ...::: :::: ..:. .. .:::: :::::::: ::.
NP_004 TPQPSRPVSPAGPPEGVPEEAQPPRLGQE--RDPGGITAGSTDEPPMLTKEEPVPELLEA
120 130 140 150 160 170
180 190 200
pF1KE2 QVVE-----------------EEEDS-GAPPLKRFCVDQPTVPQTASES
.. : . ::: :::::::.: . :
NP_004 EAPEAYPVFEPVPPVPEAAQGDTEDSEGAPPLKRICPNAPDP
180 190 200 210
>>NP_001273455 (OMIM: 605847) B-cell CLL/lymphoma 7 prot (242 aa)
initn: 568 init1: 356 opt: 556 Z-score: 442.7 bits: 89.1 E(85289): 6.4e-18
Smith-Waterman score: 556; 51.0% identity (74.7% similar) in 194 aa overlap (1-187:1-185)
10 20 30 40 50 60
pF1KE2 MSGRSVRAETRSRAKDDIKKVMAAIEKVRKWEKKWVTVGDTSLRIFKWVPVTDSKEKEKS
:.::.::::::::::::::::::.:::::.:::.:::::::::::::::::.: .:.:.
NP_001 MAGRTVRAETRSRAKDDIKKVMATIEKVRRWEKRWVTVGDTSLRIFKWVPVVDPQEEERR
10 20 30 40 50 60
70 80 90 100 110
pF1KE2 KSNSSA----AREPNGFPSDASANSSL-LLEFQDENSNQSSVSDVYQLKVDSSTNSSP--
.....: .:: : .. ... : ::...::::::: : . .....:. ::
NP_001 RAGGGAERSRGRERRGRGASPRGGGPLILLDLNDENSNQSFHS---EGSLQKGTEPSPGG
70 80 90 100 110
120 130 140 150 160 170
pF1KE2 SPQQSESLSPAHTSDFRTDDSQPPTLGQEILEEPSLPSSEVADEPPTLTKEEPVPLETQV
.:: :. .::: . ...::: :::: ..:. .. .:::: ::::::::
NP_001 TPQPSRPVSPAGPPEGVPEEAQPPRLGQE--RDPGGITAGSTDEPPMLTKEEPVPE----
120 130 140 150 160 170
180 190 200
pF1KE2 VEEEEDSGAPPLKRFCVDQPTVPQTASES
. : ::::. .:
NP_001 LLEAEDSGVRMTRRALHEKGLKTEPLRRLLPRRGLRTNVRPSSMAVPDTRAPGGGSKAPR
180 190 200 210 220 230
>>XP_011544282 (OMIM: 605847) PREDICTED: B-cell CLL/lymp (293 aa)
initn: 579 init1: 356 opt: 551 Z-score: 437.5 bits: 88.4 E(85289): 1.2e-17
Smith-Waterman score: 551; 51.6% identity (76.6% similar) in 188 aa overlap (1-179:1-183)
10 20 30 40 50 60
pF1KE2 MSGRSVRAETRSRAKDDIKKVMAAIEKVRKWEKKWVTVGDTSLRIFKWVPVTDSKEKEKS
:.::.::::::::::::::::::.:::::.:::.:::::::::::::::::.: .:.:.
XP_011 MAGRTVRAETRSRAKDDIKKVMATIEKVRRWEKRWVTVGDTSLRIFKWVPVVDPQEEERR
10 20 30 40 50 60
70 80 90 100 110
pF1KE2 KSNSSA----AREPNGFPSDASANSSL-LLEFQDENSNQSSVSDVYQLKVDSSTNSSP--
.....: .:: : .. ... : ::...::::::: :. .....:. ::
XP_011 RAGGGAERSRGRERRGRGASPRGGGPLILLDLNDENSNQSFHSEG---SLQKGTEPSPGG
70 80 90 100 110
120 130 140 150 160 170
pF1KE2 SPQQSESLSPAHTSDFRTDDSQPPTLGQEILEEPSLPSSEVADEPPTLTKEEPVP--LET
.:: :. .::: . ...::: :::: ..:. .. .:::: :::::::: ::.
XP_011 TPQPSRPVSPAGPPEGVPEEAQPPRLGQE--RDPGGITAGSTDEPPMLTKEEPVPELLEA
120 130 140 150 160 170
180 190 200
pF1KE2 QVVEEEEDSGAPPLKRFCVDQPTVPQTASES
...: :
XP_011 ETMEMMLDKKQIQAIFLFELKMGHKAVETLRNINNTLGPGTANEHIVQWWFKKFCKEDKS
180 190 200 210 220 230
>>NP_001019979 (OMIM: 601406) B-cell CLL/lymphoma 7 prot (210 aa)
initn: 483 init1: 375 opt: 497 Z-score: 399.0 bits: 80.8 E(85289): 1.8e-15
Smith-Waterman score: 508; 45.3% identity (69.7% similar) in 201 aa overlap (1-187:1-197)
10 20 30 40 50 60
pF1KE2 MSGRSVRAETRSRAKDDIKKVMAAIEKVRKWEKKWVTVGDTSLRIFKWVPVTDSKEKEKS
:::::::::::::::::::.:::::::::::::::::::::::::.::::::. : .:.
NP_001 MSGRSVRAETRSRAKDDIKRVMAAIEKVRKWEKKWVTVGDTSLRIYKWVPVTEPKVDDKN
10 20 30 40 50 60
70 80 90 100 110
pF1KE2 KSNSSAAREPNGFPSDASANSSL--LLEFQDENSNQSSVSDVYQLKVDSSTNSSPSPQQS
:..... : : . ::: .....:.::::::..:. .: ..:.::::.:. .
NP_001 KNKKKGKDEKCGSEVTTPENSSSPGMMDMHDDNSNQSSIADASPIKQENSSNSSPAPEPN
70 80 90 100 110 120
120 130 140 150 160
pF1KE2 ESLSPAHTSDFRTDDSQPPTLGQEILE------------EPSLPSSEVADEPPTLTKEEP
: :. .. ..:..: . : : :. ::: .:. :. .
NP_001 -SAVPSDGTEAKVDEAQADGKEHPGAEDASDEQNSQSSMEHSMNSSEKVDRQPS--GDSG
130 140 150 160 170
170 180 190 200
pF1KE2 VPLETQVVEEEEDSGAPPLKRFCVDQPTVPQTASES
. ::... .. . :.:: :.
NP_001 LAAETSAISQDLE-GVPPSKKMKLEASQQNSEEM
180 190 200 210
>>NP_066273 (OMIM: 601406) B-cell CLL/lymphoma 7 protein (231 aa)
initn: 490 init1: 375 opt: 495 Z-score: 396.8 bits: 80.5 E(85289): 2.3e-15
Smith-Waterman score: 495; 43.8% identity (70.4% similar) in 203 aa overlap (1-201:1-194)
10 20 30 40 50 60
pF1KE2 MSGRSVRAETRSRAKDDIKKVMAAIEKVRKWEKKWVTVGDTSLRIFKWVPVTDSKEKEKS
:::::::::::::::::::.:::::::::::::::::::::::::.::::::. : .:.
NP_066 MSGRSVRAETRSRAKDDIKRVMAAIEKVRKWEKKWVTVGDTSLRIYKWVPVTEPKVDDKN
10 20 30 40 50 60
70 80 90 100 110
pF1KE2 KSNSSAAREPNGFPSDASANSSL--LLEFQDENSNQSSVSDVYQLKVDSSTNSSPSPQQS
:..... : : . ::: .....:.::::::..:. .: ..:.::::.:. .
NP_066 KNKKKGKDEKCGSEVTTPENSSSPGMMDMHDDNSNQSSIADASPIKQENSSNSSPAPEPN
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 ESLSPAHTSDFRTDDSQPPTLGQEILEEPSLPSSEVADEPPTLTKEEPVPLETQVVEEEE
.. :. .. ..:..: :.: .:. . ...:: . .. : .. :...
NP_066 SAV-PSDGTEAKVDEAQAD--GKE---HPG--AEDASDEQNSQSSMEHSMNSSEKVDRQP
130 140 150 160 170
180 190 200
pF1KE2 DSGAPPLKRFCVDQPTVPQTASES
:: : ::.. :.
NP_066 -SGDSGLAAETSAISQVPRSRSQRGSQIGREPIGLSGDLEGVPPSKKMKLEASQQNSEEM
180 190 200 210 220 230
>>XP_016879377 (OMIM: 605847) PREDICTED: B-cell CLL/lymp (178 aa)
initn: 478 init1: 356 opt: 469 Z-score: 378.9 bits: 76.8 E(85289): 2.3e-14
Smith-Waterman score: 469; 53.7% identity (78.5% similar) in 149 aa overlap (1-142:1-146)
10 20 30 40 50 60
pF1KE2 MSGRSVRAETRSRAKDDIKKVMAAIEKVRKWEKKWVTVGDTSLRIFKWVPVTDSKEKEKS
:.::.::::::::::::::::::.:::::.:::.:::::::::::::::::.: .:.:.
XP_016 MAGRTVRAETRSRAKDDIKKVMATIEKVRRWEKRWVTVGDTSLRIFKWVPVVDPQEEERR
10 20 30 40 50 60
70 80 90 100 110
pF1KE2 KSNSSA----AREPNGFPSDASANSSL-LLEFQDENSNQSSVSDVYQLKVDSSTNSSP--
.....: .:: : .. ... : ::...::::::: : . .....:. ::
XP_016 RAGGGAERSRGRERRGRGASPRGGGPLILLDLNDENSNQSFHS---EGSLQKGTEPSPGG
70 80 90 100 110
120 130 140 150 160 170
pF1KE2 SPQQSESLSPAHTSDFRTDDSQPPTLGQEILEEPSLPSSEVADEPPTLTKEEPVPLETQV
.:: :. .::: . ...::: ::::
XP_016 TPQPSRPVSPAGPPEGVPEEAQPPRLGQERGRTRSRGHNCWQHRRTPNADQGGACSRTAG
120 130 140 150 160 170
>>XP_016879375 (OMIM: 605847) PREDICTED: B-cell CLL/lymp (178 aa)
initn: 478 init1: 356 opt: 469 Z-score: 378.9 bits: 76.8 E(85289): 2.3e-14
Smith-Waterman score: 469; 53.7% identity (78.5% similar) in 149 aa overlap (1-142:1-146)
10 20 30 40 50 60
pF1KE2 MSGRSVRAETRSRAKDDIKKVMAAIEKVRKWEKKWVTVGDTSLRIFKWVPVTDSKEKEKS
:.::.::::::::::::::::::.:::::.:::.:::::::::::::::::.: .:.:.
XP_016 MAGRTVRAETRSRAKDDIKKVMATIEKVRRWEKRWVTVGDTSLRIFKWVPVVDPQEEERR
10 20 30 40 50 60
70 80 90 100 110
pF1KE2 KSNSSA----AREPNGFPSDASANSSL-LLEFQDENSNQSSVSDVYQLKVDSSTNSSP--
.....: .:: : .. ... : ::...::::::: : . .....:. ::
XP_016 RAGGGAERSRGRERRGRGASPRGGGPLILLDLNDENSNQSFHS---EGSLQKGTEPSPGG
70 80 90 100 110
120 130 140 150 160 170
pF1KE2 SPQQSESLSPAHTSDFRTDDSQPPTLGQEILEEPSLPSSEVADEPPTLTKEEPVPLETQV
.:: :. .::: . ...::: ::::
XP_016 TPQPSRPVSPAGPPEGVPEEAQPPRLGQERGRTRSRGHNCWQHRRTPNADQGGACSRTAG
120 130 140 150 160 170
202 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 03:47:18 2016 done: Tue Nov 8 03:47:19 2016
Total Scan time: 7.310 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]