Result of FASTA (omim) for
pFN21AE2543
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2543, 265 aa
1>>>pF1KE2543 265 - 265 aa - 265 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.9121+/-0.00045; mu= 11.0625+/- 0.028
mean_var=65.1774+/-13.127, 0's: 0 Z-trim(109.3): 9 B-trim: 291 in 1/51
Lambda= 0.158864
statistics sampled from 17411 (17419) to 17411 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.568), E-opt: 0.2 (0.204), width: 16
Scan time: 6.160
The best scores are: opt bits E(85289)
XP_006714526 (OMIM: 609022) PREDICTED: rapamycin-i (1670) 1591 373.9 1e-102
XP_011512307 (OMIM: 609022) PREDICTED: rapamycin-i (1694) 1591 373.9 1e-102
NP_689969 (OMIM: 609022) rapamycin-insensitive com (1708) 1591 373.9 1e-102
NP_001272368 (OMIM: 609022) rapamycin-insensitive (1732) 1591 373.9 1.1e-102
XP_016864801 (OMIM: 609022) PREDICTED: rapamycin-i (1692) 1392 328.3 5.6e-89
XP_016864800 (OMIM: 609022) PREDICTED: rapamycin-i (1716) 1392 328.3 5.7e-89
XP_016864802 (OMIM: 609022) PREDICTED: rapamycin-i (1679) 1253 296.5 2.2e-79
XP_011512308 (OMIM: 609022) PREDICTED: rapamycin-i (1669) 1173 278.1 7.1e-74
>>XP_006714526 (OMIM: 609022) PREDICTED: rapamycin-insen (1670 aa)
initn: 1591 init1: 1591 opt: 1591 Z-score: 1965.0 bits: 373.9 E(85289): 1e-102
Smith-Waterman score: 1591; 100.0% identity (100.0% similar) in 251 aa overlap (1-251:1-251)
10 20 30 40 50 60
pF1KE2 MAAIGRGRSLKNLRVRGRNDSGEENVPLDLTREPSDNLREILQNVARLQGVSNMRKLGHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAAIGRGRSLKNLRVRGRNDSGEENVPLDLTREPSDNLREILQNVARLQGVSNMRKLGHL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 NNFTKLLCDIGHSEEKLGFHYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NNFTKLLCDIGHSEEKLGFHYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 LKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVTNSLIAVGNDGLQER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVTNSLIAVGNDGLQER
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 DRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKT
190 200 210 220 230 240
250 260
pF1KE2 RQYVRADVELEVGTLIFFSSFKILL
:::::::::::
XP_006 RQYVRADVELERILAPYTDFHYRHSPDTAEGQLKEDREARFLASKMGIIATFRSWAGIIN
250 260 270 280 290 300
>>XP_011512307 (OMIM: 609022) PREDICTED: rapamycin-insen (1694 aa)
initn: 1591 init1: 1591 opt: 1591 Z-score: 1964.9 bits: 373.9 E(85289): 1e-102
Smith-Waterman score: 1591; 100.0% identity (100.0% similar) in 251 aa overlap (1-251:1-251)
10 20 30 40 50 60
pF1KE2 MAAIGRGRSLKNLRVRGRNDSGEENVPLDLTREPSDNLREILQNVARLQGVSNMRKLGHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAIGRGRSLKNLRVRGRNDSGEENVPLDLTREPSDNLREILQNVARLQGVSNMRKLGHL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 NNFTKLLCDIGHSEEKLGFHYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NNFTKLLCDIGHSEEKLGFHYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 LKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVTNSLIAVGNDGLQER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVTNSLIAVGNDGLQER
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 DRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKT
190 200 210 220 230 240
250 260
pF1KE2 RQYVRADVELEVGTLIFFSSFKILL
:::::::::::
XP_011 RQYVRADVELERILAPYTDFHYRHSPDTAEGQLKEDREARFLASKMGIIATFRSWAGIIN
250 260 270 280 290 300
>>NP_689969 (OMIM: 609022) rapamycin-insensitive compani (1708 aa)
initn: 1591 init1: 1591 opt: 1591 Z-score: 1964.9 bits: 373.9 E(85289): 1e-102
Smith-Waterman score: 1591; 100.0% identity (100.0% similar) in 251 aa overlap (1-251:1-251)
10 20 30 40 50 60
pF1KE2 MAAIGRGRSLKNLRVRGRNDSGEENVPLDLTREPSDNLREILQNVARLQGVSNMRKLGHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 MAAIGRGRSLKNLRVRGRNDSGEENVPLDLTREPSDNLREILQNVARLQGVSNMRKLGHL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 NNFTKLLCDIGHSEEKLGFHYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 NNFTKLLCDIGHSEEKLGFHYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 LKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVTNSLIAVGNDGLQER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 LKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVTNSLIAVGNDGLQER
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 DRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 DRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKT
190 200 210 220 230 240
250 260
pF1KE2 RQYVRADVELEVGTLIFFSSFKILL
:::::::::::
NP_689 RQYVRADVELERILAPYTDFHYRHSPDTAEGQLKEDREARFLASKMGIIATFRSWAGIIN
250 260 270 280 290 300
>>NP_001272368 (OMIM: 609022) rapamycin-insensitive comp (1732 aa)
initn: 1591 init1: 1591 opt: 1591 Z-score: 1964.8 bits: 373.9 E(85289): 1.1e-102
Smith-Waterman score: 1591; 100.0% identity (100.0% similar) in 251 aa overlap (1-251:1-251)
10 20 30 40 50 60
pF1KE2 MAAIGRGRSLKNLRVRGRNDSGEENVPLDLTREPSDNLREILQNVARLQGVSNMRKLGHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAIGRGRSLKNLRVRGRNDSGEENVPLDLTREPSDNLREILQNVARLQGVSNMRKLGHL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 NNFTKLLCDIGHSEEKLGFHYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNFTKLLCDIGHSEEKLGFHYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 LKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVTNSLIAVGNDGLQER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVTNSLIAVGNDGLQER
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 DRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKT
190 200 210 220 230 240
250 260
pF1KE2 RQYVRADVELEVGTLIFFSSFKILL
:::::::::::
NP_001 RQYVRADVELERILAPYTDFHYRHSPDTAEGQLKEDREARFLASKMGIIATFRSWAGIIN
250 260 270 280 290 300
>>XP_016864801 (OMIM: 609022) PREDICTED: rapamycin-insen (1692 aa)
initn: 1392 init1: 1392 opt: 1392 Z-score: 1718.5 bits: 328.3 E(85289): 5.6e-89
Smith-Waterman score: 1442; 93.6% identity (93.6% similar) in 251 aa overlap (1-251:1-235)
10 20 30 40 50 60
pF1KE2 MAAIGRGRSLKNLRVRGRNDSGEENVPLDLTREPSDNLREILQNVARLQGVSNMRKLGHL
::::::::::::::: :::::::::::::::::::::::::::::
XP_016 MAAIGRGRSLKNLRV----------------REPSDNLREILQNVARLQGVSNMRKLGHL
10 20 30 40
70 80 90 100 110 120
pF1KE2 NNFTKLLCDIGHSEEKLGFHYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNFTKLLCDIGHSEEKLGFHYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKV
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE2 LKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVTNSLIAVGNDGLQER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVTNSLIAVGNDGLQER
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE2 DRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKT
170 180 190 200 210 220
250 260
pF1KE2 RQYVRADVELEVGTLIFFSSFKILL
:::::::::::
XP_016 RQYVRADVELERILAPYTDFHYRHSPDTAEGQLKEDREARFLASKMGIIATFRSWAGIIN
230 240 250 260 270 280
>>XP_016864800 (OMIM: 609022) PREDICTED: rapamycin-insen (1716 aa)
initn: 1392 init1: 1392 opt: 1392 Z-score: 1718.4 bits: 328.3 E(85289): 5.7e-89
Smith-Waterman score: 1442; 93.6% identity (93.6% similar) in 251 aa overlap (1-251:1-235)
10 20 30 40 50 60
pF1KE2 MAAIGRGRSLKNLRVRGRNDSGEENVPLDLTREPSDNLREILQNVARLQGVSNMRKLGHL
::::::::::::::: :::::::::::::::::::::::::::::
XP_016 MAAIGRGRSLKNLRV----------------REPSDNLREILQNVARLQGVSNMRKLGHL
10 20 30 40
70 80 90 100 110 120
pF1KE2 NNFTKLLCDIGHSEEKLGFHYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNFTKLLCDIGHSEEKLGFHYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKV
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE2 LKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVTNSLIAVGNDGLQER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVTNSLIAVGNDGLQER
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE2 DRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKT
170 180 190 200 210 220
250 260
pF1KE2 RQYVRADVELEVGTLIFFSSFKILL
:::::::::::
XP_016 RQYVRADVELERILAPYTDFHYRHSPDTAEGQLKEDREARFLASKMGIIATFRSWAGIIN
230 240 250 260 270 280
>>XP_016864802 (OMIM: 609022) PREDICTED: rapamycin-insen (1679 aa)
initn: 1253 init1: 1253 opt: 1253 Z-score: 1546.3 bits: 296.5 E(85289): 2.2e-79
Smith-Waterman score: 1253; 100.0% identity (100.0% similar) in 198 aa overlap (54-251:1-198)
30 40 50 60 70 80
pF1KE2 ENVPLDLTREPSDNLREILQNVARLQGVSNMRKLGHLNNFTKLLCDIGHSEEKLGFHYED
::::::::::::::::::::::::::::::
XP_016 MRKLGHLNNFTKLLCDIGHSEEKLGFHYED
10 20 30
90 100 110 120 130 140
pF1KE2 IIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKVLKLKVDYLIARCIDIQQSNEVER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKVLKLKVDYLIARCIDIQQSNEVER
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE2 TQALRLVRKMITVNASLFPSSVTNSLIAVGNDGLQERDRMVRACIAIICELALQNPEVVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQALRLVRKMITVNASLFPSSVTNSLIAVGNDGLQERDRMVRACIAIICELALQNPEVVA
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE2 LRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKTRQYVRADVELEVGTLIFFSSFKI
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKTRQYVRADVELERILAPYTDFHYR
160 170 180 190 200 210
pF1KE2 LL
XP_016 HSPDTAEGQLKEDREARFLASKMGIIATFRSWAGIINLCKPGNSGIQSLIGVLCIPNMEI
220 230 240 250 260 270
>>XP_011512308 (OMIM: 609022) PREDICTED: rapamycin-insen (1669 aa)
initn: 1173 init1: 1173 opt: 1173 Z-score: 1447.3 bits: 278.1 E(85289): 7.1e-74
Smith-Waterman score: 1173; 99.5% identity (100.0% similar) in 187 aa overlap (65-251:2-188)
40 50 60 70 80 90
pF1KE2 SDNLREILQNVARLQGVSNMRKLGHLNNFTKLLCDIGHSEEKLGFHYEDIIICLRLALLN
.:::::::::::::::::::::::::::::
XP_011 MELLCDIGHSEEKLGFHYEDIIICLRLALLN
10 20 30
100 110 120 130 140 150
pF1KE2 EAKEVRAAGLRALRYLIQDSSILQKVLKLKVDYLIARCIDIQQSNEVERTQALRLVRKMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAKEVRAAGLRALRYLIQDSSILQKVLKLKVDYLIARCIDIQQSNEVERTQALRLVRKMI
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE2 TVNASLFPSSVTNSLIAVGNDGLQERDRMVRACIAIICELALQNPEVVALRGGLNTILKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVNASLFPSSVTNSLIAVGNDGLQERDRMVRACIAIICELALQNPEVVALRGGLNTILKN
100 110 120 130 140 150
220 230 240 250 260
pF1KE2 VIDCQLSRINEALITTILHLLNHPKTRQYVRADVELEVGTLIFFSSFKILL
:::::::::::::::::::::::::::::::::::::
XP_011 VIDCQLSRINEALITTILHLLNHPKTRQYVRADVELERILAPYTDFHYRHSPDTAEGQLK
160 170 180 190 200 210
XP_011 EDREARFLASKMGIIATFRSWAGIINLCKPGNSGIQSLIGVLCIPNMEIRRGLLEVLYDI
220 230 240 250 260 270
265 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 03:46:48 2016 done: Tue Nov 8 03:46:49 2016
Total Scan time: 6.160 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]