Result of FASTA (ccds) for
pFN21AE2535
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2535, 281 aa
1>>>pF1KE2535 281 - 281 aa - 281 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9776+/-0.000785; mu= 16.9191+/- 0.047
mean_var=62.8045+/-12.514, 0's: 0 Z-trim(107.1): 15 B-trim: 0 in 0/48
Lambda= 0.161837
statistics sampled from 9386 (9394) to 9386 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.678), E-opt: 0.2 (0.289), width: 16
Scan time: 1.930
The best scores are: opt bits E(32554)
CCDS10870.1 HAS3 gene_id:3038|Hs108|chr16 ( 281) 1873 445.7 1.7e-125
CCDS10871.1 HAS3 gene_id:3038|Hs108|chr16 ( 553) 1634 390.1 1.9e-108
CCDS6335.1 HAS2 gene_id:3037|Hs108|chr8 ( 552) 1041 251.6 9e-67
CCDS74436.1 HAS1 gene_id:3036|Hs108|chr19 ( 577) 361 92.9 5.8e-19
CCDS12838.1 HAS1 gene_id:3036|Hs108|chr19 ( 578) 361 92.9 5.8e-19
>>CCDS10870.1 HAS3 gene_id:3038|Hs108|chr16 (281 aa)
initn: 1873 init1: 1873 opt: 1873 Z-score: 2366.4 bits: 445.7 E(32554): 1.7e-125
Smith-Waterman score: 1873; 100.0% identity (100.0% similar) in 281 aa overlap (1-281:1-281)
10 20 30 40 50 60
pF1KE2 MPVQLTTALRVVGTSLFALAVLGGILAAYVTGYQFIHTEKHYLSFGLYGAILGLHLLIQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MPVQLTTALRVVGTSLFALAVLGGILAAYVTGYQFIHTEKHYLSFGLYGAILGLHLLIQS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LFAFLEHRRMRRAGQALKLPSPRRGSVALCIAAYQEDPDYLRKCLRSAQRISFPDLKVVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 LFAFLEHRRMRRAGQALKLPSPRRGSVALCIAAYQEDPDYLRKCLRSAQRISFPDLKVVM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VVDGNRQEDAYMLDIFHEVLGGTEQAGFFVWRSNFHEAGEGETEASLQEGMDRVRDVVRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 VVDGNRQEDAYMLDIFHEVLGGTEQAGFFVWRSNFHEAGEGETEASLQEGMDRVRDVVRA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 STFSCIMQKWGGKREVMYTAFKALGDSVDYIQVCDSDTVLDPACTIEMLRVLEEDPQVGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 STFSCIMQKWGGKREVMYTAFKALGDSVDYIQVCDSDTVLDPACTIEMLRVLEEDPQVGG
190 200 210 220 230 240
250 260 270 280
pF1KE2 VGGDVQPPGKGMAVEDDQVQAAQVRATEAWSVHQRHVSREQ
:::::::::::::::::::::::::::::::::::::::::
CCDS10 VGGDVQPPGKGMAVEDDQVQAAQVRATEAWSVHQRHVSREQ
250 260 270 280
>>CCDS10871.1 HAS3 gene_id:3038|Hs108|chr16 (553 aa)
initn: 1634 init1: 1634 opt: 1634 Z-score: 2060.5 bits: 390.1 E(32554): 1.9e-108
Smith-Waterman score: 1634; 100.0% identity (100.0% similar) in 246 aa overlap (1-246:1-246)
10 20 30 40 50 60
pF1KE2 MPVQLTTALRVVGTSLFALAVLGGILAAYVTGYQFIHTEKHYLSFGLYGAILGLHLLIQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MPVQLTTALRVVGTSLFALAVLGGILAAYVTGYQFIHTEKHYLSFGLYGAILGLHLLIQS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LFAFLEHRRMRRAGQALKLPSPRRGSVALCIAAYQEDPDYLRKCLRSAQRISFPDLKVVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 LFAFLEHRRMRRAGQALKLPSPRRGSVALCIAAYQEDPDYLRKCLRSAQRISFPDLKVVM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VVDGNRQEDAYMLDIFHEVLGGTEQAGFFVWRSNFHEAGEGETEASLQEGMDRVRDVVRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 VVDGNRQEDAYMLDIFHEVLGGTEQAGFFVWRSNFHEAGEGETEASLQEGMDRVRDVVRA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 STFSCIMQKWGGKREVMYTAFKALGDSVDYIQVCDSDTVLDPACTIEMLRVLEEDPQVGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 STFSCIMQKWGGKREVMYTAFKALGDSVDYIQVCDSDTVLDPACTIEMLRVLEEDPQVGG
190 200 210 220 230 240
250 260 270 280
pF1KE2 VGGDVQPPGKGMAVEDDQVQAAQVRATEAWSVHQRHVSREQ
::::::
CCDS10 VGGDVQILNKYDSWISFLSSVRYWMAFNVERACQSYFGCVQCISGPLGMYRNSLLQQFLE
250 260 270 280 290 300
>>CCDS6335.1 HAS2 gene_id:3037|Hs108|chr8 (552 aa)
initn: 764 init1: 483 opt: 1041 Z-score: 1312.3 bits: 251.6 E(32554): 9e-67
Smith-Waterman score: 1041; 61.8% identity (87.0% similar) in 238 aa overlap (9-246:10-243)
10 20 30 40 50
pF1KE2 MPVQLTTALRVVGTSLFALAVLGGILAAYVTGYQFIHTEKHYLSFGLYGAILGLHLLIQ
::..::.::....: :: :::..:::::.:...:.:::::::.:. ::.::
CCDS63 MHCERFLCILRIIGTTLFGVSLLLGITAAYIVGYQFIQTDNYYFSFGLYGAFLASHLIIQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 SLFAFLEHRRMRRAGQALKLPSPRRGSVALCIAAYQEDPDYLRKCLRSAQRISFPDLKVV
:::::::::.:... :. : .:::::::::::::::::::.:..:...: .:::
CCDS63 SLFAFLEHRKMKKS---LETPIKLNKTVALCIAAYQEDPDYLRKCLQSVKRLTYPGIKVV
70 80 90 100 110
120 130 140 150 160 170
pF1KE2 MVVDGNRQEDAYMLDIFHEVLGGTEQAGFFVWRSNFHEAGEGETEASLQEGMDRVRDVVR
::.::: ..: ::.::: ::.: .... ..:..:::: : :::. : .:. ..: ..:
CCDS63 MVIDGNSEDDLYMMDIFSEVMG-RDKSATYIWKNNFHEKGPGETDESHKESSQHVTQLVL
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE2 ASTFSCIMQKWGGKREVMYTAFKALGDSVDYIQVCDSDTVLDPACTIEMLRVLEEDPQVG
.. :::::::::::::::::.::: ::::.:::::::.:::: ..::..::::::.::
CCDS63 SNKSICIMQKWGGKREVMYTAFRALGRSVDYVQVCDSDTMLDPASSVEMVKVLEEDPMVG
180 190 200 210 220 230
240 250 260 270 280
pF1KE2 GVGGDVQPPGKGMAVEDDQVQAAQVRATEAWSVHQRHVSREQ
:::::::
CCDS63 GVGGDVQILNKYDSWISFLSSVRYWMAFNIERACQSYFGCVQCISGPLGMYRNSLLHEFV
240 250 260 270 280 290
>>CCDS74436.1 HAS1 gene_id:3036|Hs108|chr19 (577 aa)
initn: 731 init1: 359 opt: 361 Z-score: 453.9 bits: 92.9 E(32554): 5.8e-19
Smith-Waterman score: 765; 50.8% identity (70.8% similar) in 250 aa overlap (10-246:20-267)
10 20 30 40 50
pF1KE2 MPVQLTTALRVVGTSLFALAVLGGILAAYVTGYQFIHTEKHYLSFGLYGA
: : : ::: .:: . ::..: . . :.::::::
CCDS74 MRQDAPKPTPAACRCSGLARRVLTIAFALLILGLMTWAYAAGVPLASDRYGLLAFGLYGA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 ILGLHLLIQSLFAFLEHRRMRRAGQALKLPSPRRGSVALCIAAYQEDPDYLRKCLRSAQR
.:. ::. :::::.:::::. :... : . :::: :.:::::: :::.:: ::.
CCDS74 FLSAHLVAQSLFAYLEHRRVAAAARG-PLDAATARSVALTISAYQEDPAYLRQCLASARA
70 80 90 100 110
120 130 140 150 160
pF1KE2 ISFPD--LKVVMVVDGNRQEDAYMLDIFHEVLGGTEQAGFFVWRSNFHEAGEGETEASLQ
. .: :.:.::::::: :: ::.:.:.::.. . : . :: .:.:. : . ...
CCDS74 LLYPRARLRVLMVVDGNRAEDLYMVDMFREVFADEDPATY-VWDGNYHQPWEPAAAGAVG
120 130 140 150 160 170
170 180 190 200 210
pF1KE2 EGMDR-----------VRDVVRASTFSCIMQKWGGKREVMYTAFKALGDSVDYIQVCDSD
: : :. .::. :. :.:::::::::::::::::::::.::::::
CCDS74 AGAYREVEAEDPGRLAVEALVRTRRCVCVAQRWGGKREVMYTAFKALGDSVDYVQVCDSD
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE2 TVLDPACTIEMLRVLEEDPQVGGVGGDVQPPGKGMAVEDDQVQAAQVRATEAWSVHQRHV
: ::: .:..:::.:::.::.:::::.
CCDS74 TRLDPMALLELVRVLDEDPRVGAVGGDVRILNPLDSWVSFLSSLRYWVAFNVERACQSYF
240 250 260 270 280 290
>>CCDS12838.1 HAS1 gene_id:3036|Hs108|chr19 (578 aa)
initn: 731 init1: 359 opt: 361 Z-score: 453.9 bits: 92.9 E(32554): 5.8e-19
Smith-Waterman score: 765; 50.8% identity (70.8% similar) in 250 aa overlap (10-246:21-268)
10 20 30 40
pF1KE2 MPVQLTTALRVVGTSLFALAVLGGILAAYVTGYQFIHTEKHYLSFGLYG
: : : ::: .:: . ::..: . . :.:::::
CCDS12 MRQQDAPKPTPAACRCSGLARRVLTIAFALLILGLMTWAYAAGVPLASDRYGLLAFGLYG
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE2 AILGLHLLIQSLFAFLEHRRMRRAGQALKLPSPRRGSVALCIAAYQEDPDYLRKCLRSAQ
:.:. ::. :::::.:::::. :... : . :::: :.:::::: :::.:: ::.
CCDS12 AFLSAHLVAQSLFAYLEHRRVAAAARG-PLDAATARSVALTISAYQEDPAYLRQCLASAR
70 80 90 100 110
110 120 130 140 150 160
pF1KE2 RISFPD--LKVVMVVDGNRQEDAYMLDIFHEVLGGTEQAGFFVWRSNFHEAGEGETEASL
. .: :.:.::::::: :: ::.:.:.::.. . : . :: .:.:. : . ...
CCDS12 ALLYPRARLRVLMVVDGNRAEDLYMVDMFREVFADEDPATY-VWDGNYHQPWEPAAAGAV
120 130 140 150 160 170
170 180 190 200 210
pF1KE2 QEGMDR-----------VRDVVRASTFSCIMQKWGGKREVMYTAFKALGDSVDYIQVCDS
: : :. .::. :. :.:::::::::::::::::::::.:::::
CCDS12 GAGAYREVEAEDPGRLAVEALVRTRRCVCVAQRWGGKREVMYTAFKALGDSVDYVQVCDS
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE2 DTVLDPACTIEMLRVLEEDPQVGGVGGDVQPPGKGMAVEDDQVQAAQVRATEAWSVHQRH
:: ::: .:..:::.:::.::.:::::.
CCDS12 DTRLDPMALLELVRVLDEDPRVGAVGGDVRILNPLDSWVSFLSSLRYWVAFNVERACQSY
240 250 260 270 280 290
281 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 03:35:10 2016 done: Tue Nov 8 03:35:10 2016
Total Scan time: 1.930 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]