Result of FASTA (ccds) for
pFN21AE2509
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2509, 754 aa
1>>>pF1KE2509 754 - 754 aa - 754 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.5589+/- 0.001; mu= 9.5495+/- 0.060
mean_var=122.5162+/-25.418, 0's: 0 Z-trim(107.1): 52 B-trim: 87 in 1/50
Lambda= 0.115872
statistics sampled from 9322 (9360) to 9322 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.651), E-opt: 0.2 (0.288), width: 16
Scan time: 3.860
The best scores are: opt bits E(32554)
CCDS32467.1 LRRC36 gene_id:55282|Hs108|chr16 ( 754) 4908 832.2 0
CCDS58474.1 LRRC36 gene_id:55282|Hs108|chr16 ( 633) 4077 693.3 3.1e-199
CCDS34126.1 CEP72 gene_id:55722|Hs108|chr5 ( 647) 468 90.0 1.3e-17
>>CCDS32467.1 LRRC36 gene_id:55282|Hs108|chr16 (754 aa)
initn: 4908 init1: 4908 opt: 4908 Z-score: 4440.0 bits: 832.2 E(32554): 0
Smith-Waterman score: 4908; 100.0% identity (100.0% similar) in 754 aa overlap (1-754:1-754)
10 20 30 40 50 60
pF1KE2 MAEQWELDEEGIRRLGALTLEQPELVESLSLQGSYAGKIHSIGDAFRNFKNLRSLDLSRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 MAEQWELDEEGIRRLGALTLEQPELVESLSLQGSYAGKIHSIGDAFRNFKNLRSLDLSRN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LITSLKGIQYLCSLQDLNLYYNNIPSLVEVSRLQPLPFLKELDLRLNPVVRKDTDYRLFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 LITSLKGIQYLCSLQDLNLYYNNIPSLVEVSRLQPLPFLKELDLRLNPVVRKDTDYRLFA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VYTLQTLEKLDDRTVREGERKAAKLHFSQLGNSENFLLEVEKSSREKTMKNCVTGESSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 VYTLQTLEKLDDRTVREGERKAAKLHFSQLGNSENFLLEVEKSSREKTMKNCVTGESSAS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 KVSANVDSRIEMDSNKGLFIPFPNREIKDSLSTSATQGNGTRDQKLDTFPLGTQTQEVAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 KVSANVDSRIEMDSNKGLFIPFPNREIKDSLSTSATQGNGTRDQKLDTFPLGTQTQEVAR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 REMPSDNHQEDEFRHYSPRQSTVRSPEKMTREGYQVSFLDNKSSGSSPEKELIPKPDTFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 REMPSDNHQEDEFRHYSPRQSTVRSPEKMTREGYQVSFLDNKSSGSSPEKELIPKPDTFH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 LTHDASLSKCLDVGDSSQIHPYQLPSDVGLENYDSCYSQTLSLHGSLGKRPQRSKNYQEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 LTHDASLSKCLDVGDSSQIHPYQLPSDVGLENYDSCYSQTLSLHGSLGKRPQRSKNYQEY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 SIKPSNDIKTTASHSCGDLLTSLSNPDSSTGRLLKLSSDLYATTHFNSDPAVLVNVEQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 SIKPSNDIKTTASHSCGDLLTSLSNPDSSTGRLLKLSSDLYATTHFNSDPAVLVNVEQQL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 STSLDDLTPAHGSVPNNAVLGNRTTPLRTLLLSPGTSEHRKIFTKRSLSPSKRGFKWKDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 STSLDDLTPAHGSVPNNAVLGNRTTPLRTLLLSPGTSEHRKIFTKRSLSPSKRGFKWKDN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 ILANLNLKHGFQDATGSEPLSSDLGSLHGLAGNHSPPISARTPHVATVLRQLLELVDKHW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 ILANLNLKHGFQDATGSEPLSSDLGSLHGLAGNHSPPISARTPHVATVLRQLLELVDKHW
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 NGSGSLLLNKKFLGPARDLLLSLVVPAPSQPRCCSHPEDTMKAFCRRELELKEAAQLVPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 NGSGSLLLNKKFLGPARDLLLSLVVPAPSQPRCCSHPEDTMKAFCRRELELKEAAQLVPN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 DMESLKQKLVRVLEENLILSEKIQQLEEGAAISIVSGQQSHTYDDLLHKNQQLTMQVACL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 DMESLKQKLVRVLEENLILSEKIQQLEEGAAISIVSGQQSHTYDDLLHKNQQLTMQVACL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 NQELAQLKKLEKTVAILHESQRSLVVTNEYLLQQLNKEPKGYSGKALLPPEKGHHLGRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS32 NQELAQLKKLEKTVAILHESQRSLVVTNEYLLQQLNKEPKGYSGKALLPPEKGHHLGRSS
670 680 690 700 710 720
730 740 750
pF1KE2 PFGKSTLSSSSPVAHETGQYLIQSVLDAAPEPGL
::::::::::::::::::::::::::::::::::
CCDS32 PFGKSTLSSSSPVAHETGQYLIQSVLDAAPEPGL
730 740 750
>>CCDS58474.1 LRRC36 gene_id:55282|Hs108|chr16 (633 aa)
initn: 4077 init1: 4077 opt: 4077 Z-score: 3690.4 bits: 693.3 E(32554): 3.1e-199
Smith-Waterman score: 4077; 100.0% identity (100.0% similar) in 624 aa overlap (131-754:10-633)
110 120 130 140 150 160
pF1KE2 ELDLRLNPVVRKDTDYRLFAVYTLQTLEKLDDRTVREGERKAAKLHFSQLGNSENFLLEV
::::::::::::::::::::::::::::::
CCDS58 MLRPRFLPPDDRTVREGERKAAKLHFSQLGNSENFLLEV
10 20 30
170 180 190 200 210 220
pF1KE2 EKSSREKTMKNCVTGESSASKVSANVDSRIEMDSNKGLFIPFPNREIKDSLSTSATQGNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 EKSSREKTMKNCVTGESSASKVSANVDSRIEMDSNKGLFIPFPNREIKDSLSTSATQGNG
40 50 60 70 80 90
230 240 250 260 270 280
pF1KE2 TRDQKLDTFPLGTQTQEVARREMPSDNHQEDEFRHYSPRQSTVRSPEKMTREGYQVSFLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 TRDQKLDTFPLGTQTQEVARREMPSDNHQEDEFRHYSPRQSTVRSPEKMTREGYQVSFLD
100 110 120 130 140 150
290 300 310 320 330 340
pF1KE2 NKSSGSSPEKELIPKPDTFHLTHDASLSKCLDVGDSSQIHPYQLPSDVGLENYDSCYSQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 NKSSGSSPEKELIPKPDTFHLTHDASLSKCLDVGDSSQIHPYQLPSDVGLENYDSCYSQT
160 170 180 190 200 210
350 360 370 380 390 400
pF1KE2 LSLHGSLGKRPQRSKNYQEYSIKPSNDIKTTASHSCGDLLTSLSNPDSSTGRLLKLSSDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 LSLHGSLGKRPQRSKNYQEYSIKPSNDIKTTASHSCGDLLTSLSNPDSSTGRLLKLSSDL
220 230 240 250 260 270
410 420 430 440 450 460
pF1KE2 YATTHFNSDPAVLVNVEQQLSTSLDDLTPAHGSVPNNAVLGNRTTPLRTLLLSPGTSEHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 YATTHFNSDPAVLVNVEQQLSTSLDDLTPAHGSVPNNAVLGNRTTPLRTLLLSPGTSEHR
280 290 300 310 320 330
470 480 490 500 510 520
pF1KE2 KIFTKRSLSPSKRGFKWKDNILANLNLKHGFQDATGSEPLSSDLGSLHGLAGNHSPPISA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 KIFTKRSLSPSKRGFKWKDNILANLNLKHGFQDATGSEPLSSDLGSLHGLAGNHSPPISA
340 350 360 370 380 390
530 540 550 560 570 580
pF1KE2 RTPHVATVLRQLLELVDKHWNGSGSLLLNKKFLGPARDLLLSLVVPAPSQPRCCSHPEDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 RTPHVATVLRQLLELVDKHWNGSGSLLLNKKFLGPARDLLLSLVVPAPSQPRCCSHPEDT
400 410 420 430 440 450
590 600 610 620 630 640
pF1KE2 MKAFCRRELELKEAAQLVPNDMESLKQKLVRVLEENLILSEKIQQLEEGAAISIVSGQQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 MKAFCRRELELKEAAQLVPNDMESLKQKLVRVLEENLILSEKIQQLEEGAAISIVSGQQS
460 470 480 490 500 510
650 660 670 680 690 700
pF1KE2 HTYDDLLHKNQQLTMQVACLNQELAQLKKLEKTVAILHESQRSLVVTNEYLLQQLNKEPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 HTYDDLLHKNQQLTMQVACLNQELAQLKKLEKTVAILHESQRSLVVTNEYLLQQLNKEPK
520 530 540 550 560 570
710 720 730 740 750
pF1KE2 GYSGKALLPPEKGHHLGRSSPFGKSTLSSSSPVAHETGQYLIQSVLDAAPEPGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 GYSGKALLPPEKGHHLGRSSPFGKSTLSSSSPVAHETGQYLIQSVLDAAPEPGL
580 590 600 610 620 630
>>CCDS34126.1 CEP72 gene_id:55722|Hs108|chr5 (647 aa)
initn: 586 init1: 422 opt: 468 Z-score: 429.7 bits: 90.0 E(32554): 1.3e-17
Smith-Waterman score: 523; 27.6% identity (51.0% similar) in 724 aa overlap (7-697:10-608)
10 20 30 40 50
pF1KE2 MAEQWELDEEGIRRLGALTLEQPELVE--SLSLQGSYAGKIHSIGDAFRNFKNLRSL
:.::..: ..: . .:.: :::. :.: :: .: .. .. .:.::
CCDS34 MARAGPRLVLSEEAVRAKSGLG-PHRDLAELQSLSIPGTYQEKITHLGHSLMSLTGLKSL
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 DLSRNLITSLKGIQYLCSLQDLNLYYNNIPSLVEVSRLQPLPFLKELDLRLNPVVRKDTD
::::: ..::.::::: .:..:::::: : ::.:: ::. : : ..:.::::::. . :
CCDS34 DLSRNSLVSLEGIQYLTALESLNLYYNCISSLAEVFRLHALTELVDVDFRLNPVVKVEPD
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 YRLFAVYTLQTLEKLDDRTVREGERKAAKLHFSQLGNSENFLLEVEKSSREKTMKNCVTG
::::.:. : :..:::: :: .::::..:::. ::. : : : ..:.
CCDS34 YRLFVVHLLPKLQQLDDRPVRASERKASRLHFA----SEDSLDS--KESVPASLKEGRPH
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE2 ESSASKVSANVDSRIEMDSNKGLFIPFPNREIKD----SLSTSATQGNGTRDQKLDTFPL
. :. . : . . . ::.. . . . : ::: .: . :.. .
CCDS34 HPRAKCTEALAKQSLVMDADDEAVLNLIAECEWDLGRPPGSTSFSQKGREADSRGSQESR
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE2 GTQTQEVARREMPSDNHQEDEFRHYSPRQSTVRSPEKMTREGYQVSFLDNKSSGSSPEKE
. .... . ....: : :. : : . ::: :. :. ::
CCDS34 HLLSPQLVQYQCGDSGKQGRETRRSSCRGCCL---EKMPWS--QLCGELPPLYGAEPEAS
240 250 260 270 280
300 310 320 330 340
pF1KE2 LIPKPDTFHLTHDASLSKCLDVGDSSQIHPYQLPSDVGLENYDSCYSQTLSLHGSL--GK
:.: :. : :. .. :: :: :.: : . :
CCDS34 RAPRPHTYFTPHPDSM-----------------------DTEDSASSQKLDLSGEMVPGP
290 300 310 320
350 360 370 380 390 400
pF1KE2 RPQRSKNYQEYSIKPSNDIKTTASHSCGDLLTSLSNPDSSTGRLLKLSSDLYATTHFNSD
: .: .. : . ..: ... .:. :. :: .:
CCDS34 LPAPGKCRKRRM--PVGRFQTFSDQE------GLGCPER---------------THGSSV
330 340 350 360
410 420 430 440 450 460
pF1KE2 PAVLVNVEQQLSTSLDDLTPAHGSVPNNAVLGNRTTPLRTLLLSPGTSEHRKIFTKRSLS
: . : : .: . .... ::: .: .:: .. .::
CCDS34 P--------KESLSRQDSSESRNG--------------RTLS-QPEASETEE---QRS--
370 380 390
470 480 490 500 510 520
pF1KE2 PSKRGFKWKDNILANLNLKHGFQDATGSEPLSSDLGSLHGLAGNHSPPISARTPHVATVL
.: :. : :.:: . .: :..:
CCDS34 -------------------RGVTDTREPSP------------GSHSALPGKKTALQAALL
400 410 420
530 540 550 560 570 580
pF1KE2 RQLLELVDKHWNGSGSLLLNKKFLGPARDLLLSLVVPAPSQPRCCSHPEDTMK-AFCRRE
. ::.:::. :.: :: :. ::. :: .: :. . .: ::. . :. .
CCDS34 ETLLDLVDRSWGGCRSLHSNEAFLAQARHILSSVEEFTAAQDSSAMVGEDVGSLALESKS
430 440 450 460 470 480
590 600 610 620
pF1KE2 LELKEAAQL----------------VPNDMESLKQKLVRVLEEN-----LILSEK--IQQ
:. . : : . .....:.:.: . :::: :.:: : ...
CCDS34 LQSRLAEQQQQHAREMSEVTAELHHTHKELDDLRQHLDKSLEENSRLKSLLLSMKKEVKS
490 500 510 520 530 540
630 640 650 660 670 680
pF1KE2 LEEGAAISI-VSGQQSHTYDDLLHKNQQLTMQVACLNQELAQLKKLEKTVAILHESQRSL
. .:.... ..: :. . ..: ... :.:.: . :... . .:.::. ::
CCDS34 ADTAATLNLQIAGLQTSV--------KRLCGEIVELKQHLEHYDKIQELTQMLQESHSSL
550 560 570 580 590
690 700 710 720 730 740
pF1KE2 VVTNEYLLQQLNKEPKGYSGKALLPPEKGHHLGRSSPFGKSTLSSSSPVAHETGQYLIQS
: :::.:::.:..
CCDS34 VSTNEHLLQELSQVRAQHRAEVEQMHWSYQELKKTMALFPHSSASHGGCQAC
600 610 620 630 640
754 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 02:46:20 2016 done: Tue Nov 8 02:46:21 2016
Total Scan time: 3.860 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]