Result of FASTA (omim) for
pFN21AE2437
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2437, 455 aa
1>>>pF1KE2437 455 - 455 aa - 455 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.3757+/-0.000415; mu= -6.8811+/- 0.026
mean_var=495.5540+/-102.221, 0's: 0 Z-trim(124.8): 442 B-trim: 2029 in 1/60
Lambda= 0.057614
statistics sampled from 46784 (47259) to 46784 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.815), E-opt: 0.2 (0.554), width: 16
Scan time: 8.700
The best scores are: opt bits E(85289)
NP_005668 (OMIM: 603033,603034) acetylcholinestera ( 455) 3379 295.0 2.8e-79
NP_536799 (OMIM: 603033,603034) acetylcholinestera ( 445) 3163 277.0 7e-74
NP_536800 (OMIM: 603033,603034) acetylcholinestera ( 421) 2627 232.4 1.7e-60
NP_065084 (OMIM: 120251) collagen alpha-1(VIII) ch ( 744) 679 70.8 1.4e-11
NP_001841 (OMIM: 120251) collagen alpha-1(VIII) ch ( 744) 679 70.8 1.4e-11
XP_011532992 (OMIM: 610043) PREDICTED: collagen al ( 548) 674 70.2 1.5e-11
XP_016883155 (OMIM: 120270,600969,603932) PREDICTE ( 486) 672 70.0 1.6e-11
XP_011526847 (OMIM: 120270,600969,603932) PREDICTE ( 552) 672 70.1 1.7e-11
XP_011526344 (OMIM: 120216) PREDICTED: collagen al (1744) 684 71.7 1.8e-11
NP_056534 (OMIM: 120216) collagen alpha-3(V) chain (1745) 684 71.7 1.8e-11
NP_001844 (OMIM: 120270,600969,603932) collagen al ( 684) 672 70.2 2e-11
XP_016869755 (OMIM: 120215,130000) PREDICTED: coll (1715) 679 71.2 2.4e-11
NP_001265003 (OMIM: 120215,130000) collagen alpha- (1838) 679 71.3 2.5e-11
NP_000084 (OMIM: 120215,130000) collagen alpha-1(V (1838) 679 71.3 2.5e-11
XP_011517442 (OMIM: 608461,615155) PREDICTED: coll (1842) 672 70.7 3.8e-11
XP_011508875 (OMIM: 120190,130000) PREDICTED: coll (1453) 669 70.3 3.8e-11
NP_000384 (OMIM: 120190,130000) collagen alpha-2(V (1499) 669 70.3 3.9e-11
XP_016855830 (OMIM: 120326) PREDICTED: collagen al (1028) 664 69.7 4.1e-11
XP_016855829 (OMIM: 120326) PREDICTED: collagen al (1077) 664 69.7 4.2e-11
XP_011539030 (OMIM: 120326) PREDICTED: collagen al (1089) 664 69.8 4.2e-11
NP_000081 (OMIM: 120180,130020,130050) collagen al (1466) 666 70.1 4.6e-11
XP_011533735 (OMIM: 120110,156500) PREDICTED: coll ( 680) 657 68.9 4.7e-11
NP_000484 (OMIM: 120110,156500) collagen alpha-1(X ( 680) 657 68.9 4.7e-11
XP_016865737 (OMIM: 120110,156500) PREDICTED: coll ( 680) 657 68.9 4.7e-11
XP_016865738 (OMIM: 120110,156500) PREDICTED: coll ( 680) 657 68.9 4.7e-11
XP_006715396 (OMIM: 120110,156500) PREDICTED: coll ( 680) 657 68.9 4.7e-11
XP_011533734 (OMIM: 120110,156500) PREDICTED: coll ( 680) 657 68.9 4.7e-11
XP_011539029 (OMIM: 120326) PREDICTED: collagen al (1302) 664 69.8 4.8e-11
XP_011519350 (OMIM: 120130,175780,180000,607595,61 (1605) 666 70.1 4.9e-11
NP_001836 (OMIM: 120130,175780,180000,607595,61177 (1669) 666 70.1 5e-11
XP_011539026 (OMIM: 120326) PREDICTED: collagen al (1563) 664 69.9 5.4e-11
XP_005270538 (OMIM: 120326) PREDICTED: collagen al (1588) 664 69.9 5.4e-11
XP_016855828 (OMIM: 120326) PREDICTED: collagen al (1592) 664 69.9 5.4e-11
XP_016855827 (OMIM: 120326) PREDICTED: collagen al (1593) 664 69.9 5.4e-11
NP_001847 (OMIM: 120326) collagen alpha-1(XVI) cha (1604) 664 69.9 5.5e-11
XP_011517447 (OMIM: 608461,615155) PREDICTED: coll (1049) 656 69.1 6.6e-11
XP_006717373 (OMIM: 608461,615155) PREDICTED: coll (1087) 656 69.1 6.7e-11
XP_016874320 (OMIM: 108300,120140,132450,150600,15 (1305) 658 69.3 6.8e-11
NP_149162 (OMIM: 108300,120140,132450,150600,15121 (1418) 658 69.4 7.1e-11
XP_016874319 (OMIM: 108300,120140,132450,150600,15 (1465) 658 69.4 7.3e-11
NP_001835 (OMIM: 108300,120140,132450,150600,15121 (1487) 658 69.4 7.4e-11
XP_016874318 (OMIM: 108300,120140,132450,150600,15 (1534) 658 69.4 7.5e-11
XP_016874317 (OMIM: 108300,120140,132450,150600,15 (1535) 658 69.4 7.5e-11
XP_016870728 (OMIM: 608461,615155) PREDICTED: coll (1214) 655 69.1 7.7e-11
XP_011539019 (OMIM: 120260,600204,603932,614284) P ( 508) 645 67.8 7.7e-11
XP_011517446 (OMIM: 608461,615155) PREDICTED: coll (1352) 656 69.2 7.8e-11
XP_011517445 (OMIM: 608461,615155) PREDICTED: coll (1353) 656 69.2 7.8e-11
NP_000485 (OMIM: 113811,122400,226650) collagen al (1497) 657 69.3 7.8e-11
XP_005257116 (OMIM: 114000,120150,130000,130060,16 (1158) 654 69.0 7.9e-11
XP_011522643 (OMIM: 114000,120150,130000,130060,16 (1398) 656 69.2 7.9e-11
>>NP_005668 (OMIM: 603033,603034) acetylcholinesterase c (455 aa)
initn: 3379 init1: 3379 opt: 3379 Z-score: 1544.3 bits: 295.0 E(85289): 2.8e-79
Smith-Waterman score: 3379; 100.0% identity (100.0% similar) in 455 aa overlap (1-455:1-455)
10 20 30 40 50 60
pF1KE2 MVVLNPMTLGIYLQLFFLSIVSQPTFINSVLPISAALPSLDQKKRGGHKACCLLTPPPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MVVLNPMTLGIYLQLFFLSIVSQPTFINSVLPISAALPSLDQKKRGGHKACCLLTPPPPP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGKTGPKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGKTGPKG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 EKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 SRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 QKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPGRCLCGPTMNVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPGRCLCGPTMNVN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 NPSYGESVYGPSSPRVPVIFVVNNQEELERLNTQNAIAFRRDQRSLYFKDSLGWLPIQLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NPSYGESVYGPSSPRVPVIFVVNNQEELERLNTQNAIAFRRDQRSLYFKDSLGWLPIQLT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 PFYPVDYTADQHGTCGDGLLQPGEECDDGNSDVGDDCIRCHRAYCGDGHRHEGVEDCDGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PFYPVDYTADQHGTCGDGLLQPGEECDDGNSDVGDDCIRCHRAYCGDGHRHEGVEDCDGS
370 380 390 400 410 420
430 440 450
pF1KE2 DFGYLTCETYLPGSYGDLQCTQYCYIDSTPCRYFT
:::::::::::::::::::::::::::::::::::
NP_005 DFGYLTCETYLPGSYGDLQCTQYCYIDSTPCRYFT
430 440 450
>>NP_536799 (OMIM: 603033,603034) acetylcholinesterase c (445 aa)
initn: 3162 init1: 3162 opt: 3163 Z-score: 1447.4 bits: 277.0 E(85289): 7e-74
Smith-Waterman score: 3163; 98.1% identity (98.8% similar) in 432 aa overlap (27-455:14-445)
10 20 30 40 50
pF1KE2 MVVLNPMTLGIYLQLFFLSIVSQPTFINSVLPISA---ALPSLDQKKRGGHKACCLLTPP
:...: :: ::::::::::::::::::::::
NP_536 MTGSSFSLAHLLIISGLLCYSAGCLALPSLDQKKRGGHKACCLLTPP
10 20 30 40
60 70 80 90 100 110
pF1KE2 PPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGKTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_536 PPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGKTG
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE2 PKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_536 PKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKG
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE2 YPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_536 YPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRG
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE2 KQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPGRCLCGPTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_536 KQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPGRCLCGPTM
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE2 NVNNPSYGESVYGPSSPRVPVIFVVNNQEELERLNTQNAIAFRRDQRSLYFKDSLGWLPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_536 NVNNPSYGESVYGPSSPRVPVIFVVNNQEELERLNTQNAIAFRRDQRSLYFKDSLGWLPI
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE2 QLTPFYPVDYTADQHGTCGDGLLQPGEECDDGNSDVGDDCIRCHRAYCGDGHRHEGVEDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_536 QLTPFYPVDYTADQHGTCGDGLLQPGEECDDGNSDVGDDCIRCHRAYCGDGHRHEGVEDC
350 360 370 380 390 400
420 430 440 450
pF1KE2 DGSDFGYLTCETYLPGSYGDLQCTQYCYIDSTPCRYFT
::::::::::::::::::::::::::::::::::::::
NP_536 DGSDFGYLTCETYLPGSYGDLQCTQYCYIDSTPCRYFT
410 420 430 440
>>NP_536800 (OMIM: 603033,603034) acetylcholinesterase c (421 aa)
initn: 3125 init1: 2626 opt: 2627 Z-score: 1206.9 bits: 232.4 E(85289): 1.7e-60
Smith-Waterman score: 3061; 92.5% identity (92.5% similar) in 455 aa overlap (1-455:1-421)
10 20 30 40 50 60
pF1KE2 MVVLNPMTLGIYLQLFFLSIVSQPTFINSVLPISAALPSLDQKKRGGHKACCLLTPPPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_536 MVVLNPMTLGIYLQLFFLSIVSQPTFINSVLPISAALPSLDQKKRGGHKACCLLTPPPPP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGKTGPKG
::::::::::::: :::::::::::::
NP_536 LFPPPFFRGGRSP----------------------------------GPPGLPGKTGPKG
70 80
130 140 150 160 170 180
pF1KE2 EKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_536 EKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPG
90 100 110 120 130 140
190 200 210 220 230 240
pF1KE2 SRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_536 SRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQG
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE2 QKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPGRCLCGPTMNVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_536 QKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERGFPGPPGRCLCGPTMNVN
210 220 230 240 250 260
310 320 330 340 350 360
pF1KE2 NPSYGESVYGPSSPRVPVIFVVNNQEELERLNTQNAIAFRRDQRSLYFKDSLGWLPIQLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_536 NPSYGESVYGPSSPRVPVIFVVNNQEELERLNTQNAIAFRRDQRSLYFKDSLGWLPIQLT
270 280 290 300 310 320
370 380 390 400 410 420
pF1KE2 PFYPVDYTADQHGTCGDGLLQPGEECDDGNSDVGDDCIRCHRAYCGDGHRHEGVEDCDGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_536 PFYPVDYTADQHGTCGDGLLQPGEECDDGNSDVGDDCIRCHRAYCGDGHRHEGVEDCDGS
330 340 350 360 370 380
430 440 450
pF1KE2 DFGYLTCETYLPGSYGDLQCTQYCYIDSTPCRYFT
:::::::::::::::::::::::::::::::::::
NP_536 DFGYLTCETYLPGSYGDLQCTQYCYIDSTPCRYFT
390 400 410 420
>>NP_065084 (OMIM: 120251) collagen alpha-1(VIII) chain (744 aa)
initn: 1423 init1: 564 opt: 679 Z-score: 328.9 bits: 70.8 E(85289): 1.4e-11
Smith-Waterman score: 719; 45.2% identity (58.4% similar) in 250 aa overlap (65-289:327-563)
40 50 60 70 80 90
pF1KE2 AALPSLDQKKRGGHKACCLLTPPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCM
: : ::.. : . . : .
NP_065 PQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPG---------PPGL
300 310 320 330 340
100 110 120 130 140 150
pF1KE2 QGSLGSPGPPGPQGPPGL---PGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGP
: .:.:: :::.: :. :: ::.:::: .: :: : :: ::.::.:::.: ::
NP_065 PG-IGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGA
350 360 370 380 390 400
160 170 180 190 200
pF1KE2 ---EGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRG------EKGSRGEKGDLGPKGEKGF
::.:: : .: .: :: .: : .:.::. : : :: : .::::: :
NP_065 IGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQ
410 420 430 440 450 460
210 220 230 240 250 260
pF1KE2 PGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGR
: ::. : : .:::::::: : .: : :: : : :: .:::: :::.:.::
NP_065 KGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGI---PGIGGPSGPIGPPGIPGPKGEPGL
470 480 490 500 510 520
270 280 290 300
pF1KE2 PGPPG-P------------PPAGQLIMGPKGERGFPGPPGRCLCGPTMNVNNPSYGESVY
::::: : ::. .::.:. :.:::::
NP_065 PGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGE
530 540 550 560 570 580
310 320 330 340 350 360
pF1KE2 GPSSPRVPVIFVVNNQEELERLNTQNAIAFRRDQRSLYFKDSLGWLPIQLTPFYPVDYTA
NP_065 YLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAPVKFNKLLYNGR
590 600 610 620 630 640
>--
initn: 487 init1: 246 opt: 535 Z-score: 264.2 bits: 58.8 E(85289): 5.6e-08
Smith-Waterman score: 653; 40.2% identity (55.1% similar) in 276 aa overlap (24-289:45-311)
10 20 30 40 50
pF1KE2 MVVLNPMTLGIYLQLFFLSIVSQPTFINSVLPISAALPSLDQKKRG---GHKA
: : . :.. .: . : : :..
NP_065 LTISLSSIRLIQAGAYYGIKPLPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGKEM
20 30 40 50 60 70
60 70 80 90 100
pF1KE2 CCLLTPPPPPLFPPPFFRGGRSPLLSPD-MKNLMLELETSQSPCMQGSLGSPGPPGPQGP
: : .: . . .: .. . . . :. .. :: : ::: :: ::
NP_065 PHLQYGKEYPHLPQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGP
80 90 100 110 120 130
110 120 130 140 150 160
pF1KE2 PGLPGKTGP--KGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLP
:::::. : ::. : : :: :.:: ::.:: :: .: :: .: :.::..: ::.:
NP_065 PGLPGHGIPGIKGKPGPQGYPGV-GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIP
140 150 160 170 180 190
170 180 190 200 210 220
pF1KE2 GSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKG--EPGIAG
: .:: : .: :: :. :. : :. ::::..: :.:: : .: : :: :: :
NP_065 GPQGPPGPHGLPGI-GKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPG
200 210 220 230 240 250
230 240 250 260 270 280
pF1KE2 HRGPTGRPGKRGKQGQKG--DSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERG
.:: : : : : : :: : :: :: :.:: :: ::: .:: : :
NP_065 VKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGP-------QGPIGVPG
260 270 280 290 300
290 300 310 320 330 340
pF1KE2 FPGPPGRCLCGPTMNVNNPSYGESVYGPSSPRVPVIFVVNNQEELERLNTQNAIAFRRDQ
::::
NP_065 VQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMG
310 320 330 340 350 360
>>NP_001841 (OMIM: 120251) collagen alpha-1(VIII) chain (744 aa)
initn: 1423 init1: 564 opt: 679 Z-score: 328.9 bits: 70.8 E(85289): 1.4e-11
Smith-Waterman score: 719; 45.2% identity (58.4% similar) in 250 aa overlap (65-289:327-563)
40 50 60 70 80 90
pF1KE2 AALPSLDQKKRGGHKACCLLTPPPPPLFPPPFFRGGRSPLLSPDMKNLMLELETSQSPCM
: : ::.. : . . : .
NP_001 PQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPG---------PPGL
300 310 320 330 340
100 110 120 130 140 150
pF1KE2 QGSLGSPGPPGPQGPPGL---PGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGP
: .:.:: :::.: :. :: ::.:::: .: :: : :: ::.::.:::.: ::
NP_001 PG-IGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGA
350 360 370 380 390 400
160 170 180 190 200
pF1KE2 ---EGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRG------EKGSRGEKGDLGPKGEKGF
::.:: : .: .: :: .: : .:.::. : : :: : .::::: :
NP_001 IGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQ
410 420 430 440 450 460
210 220 230 240 250 260
pF1KE2 PGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGR
: ::. : : .:::::::: : .: : :: : : :: .:::: :::.:.::
NP_001 KGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGI---PGIGGPSGPIGPPGIPGPKGEPGL
470 480 490 500 510 520
270 280 290 300
pF1KE2 PGPPG-P------------PPAGQLIMGPKGERGFPGPPGRCLCGPTMNVNNPSYGESVY
::::: : ::. .::.:. :.:::::
NP_001 PGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGE
530 540 550 560 570 580
310 320 330 340 350 360
pF1KE2 GPSSPRVPVIFVVNNQEELERLNTQNAIAFRRDQRSLYFKDSLGWLPIQLTPFYPVDYTA
NP_001 YLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAPVKFNKLLYNGR
590 600 610 620 630 640
>--
initn: 487 init1: 246 opt: 535 Z-score: 264.2 bits: 58.8 E(85289): 5.6e-08
Smith-Waterman score: 653; 40.2% identity (55.1% similar) in 276 aa overlap (24-289:45-311)
10 20 30 40 50
pF1KE2 MVVLNPMTLGIYLQLFFLSIVSQPTFINSVLPISAALPSLDQKKRG---GHKA
: : . :.. .: . : : :..
NP_001 LTISLSSIRLIQAGAYYGIKPLPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGKEM
20 30 40 50 60 70
60 70 80 90 100
pF1KE2 CCLLTPPPPPLFPPPFFRGGRSPLLSPD-MKNLMLELETSQSPCMQGSLGSPGPPGPQGP
: : .: . . .: .. . . . :. .. :: : ::: :: ::
NP_001 PHLQYGKEYPHLPQYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGP
80 90 100 110 120 130
110 120 130 140 150 160
pF1KE2 PGLPGKTGP--KGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLP
:::::. : ::. : : :: :.:: ::.:: :: .: :: .: :.::..: ::.:
NP_001 PGLPGHGIPGIKGKPGPQGYPGV-GKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIP
140 150 160 170 180 190
170 180 190 200 210 220
pF1KE2 GSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKG--EPGIAG
: .:: : .: :: :. :. : :. ::::..: :.:: : .: : :: :: :
NP_001 GPQGPPGPHGLPGI-GKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPG
200 210 220 230 240 250
230 240 250 260 270 280
pF1KE2 HRGPTGRPGKRGKQGQKG--DSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKGERG
.:: : : : : : :: : :: :: :.:: :: ::: .:: : :
NP_001 VKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGP-------QGPIGVPG
260 270 280 290 300
290 300 310 320 330 340
pF1KE2 FPGPPGRCLCGPTMNVNNPSYGESVYGPSSPRVPVIFVVNNQEELERLNTQNAIAFRRDQ
::::
NP_001 VQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMG
310 320 330 340 350 360
>>XP_011532992 (OMIM: 610043) PREDICTED: collagen alpha- (548 aa)
initn: 1804 init1: 521 opt: 674 Z-score: 328.2 bits: 70.2 E(85289): 1.5e-11
Smith-Waterman score: 674; 47.8% identity (58.8% similar) in 228 aa overlap (96-312:130-350)
70 80 90 100 110 120
pF1KE2 FFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGEL
: :.:::::: : : :: :::::::.
XP_011 LDGLAKIRTAREAPSECVCPPGPPGRRGKPGRRGDPGPPGPLGLDGKPGLPGPKGEKGDQ
100 110 120 130 140 150
130 140 150 160 170 180
pF1KE2 GRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEK
:. : : ::::: :: :: : : .:::: .: : : ::. : :: :: :: .::
XP_011 GQDGAAGPPGPPGPPGARGPPGDTGKDGPRGAQGPAGPKGEPGQDGEMGPKGPPGPKGEP
160 170 180 190 200 210
190 200 210 220 230 240
pF1KE2 GSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDS
: :.::: : .. :: :: :. : :::.:: :. : :: :.::.:: .: :
XP_011 GVPGKKGDDGTPSQ---PGPPGPKGEPGSMGPRGENGVDGAPGPKGEPGHRGTDGAAGPR
220 230 240 250 260 270
250 260 270 280 290
pF1KE2 GVMGPPGKPGPS---GQPGR-----PGPPGP--PPAGQLIMGPKGERGFPGPPG-RCLCG
:. : :. : . :: ::::: ::. : : ::: :.:: :: :
XP_011 GAPGLKGEQGDTVVIDYDGRILDALKGPPGPQGPPGPPGIPGAKGELGLPGAPGIDGEKG
280 290 300 310 320 330
300 310 320 330 340 350
pF1KE2 PTMNVNNPSYGESVYGPSSPRVPVIFVVNNQEELERLNTQNAIAFRRDQRSLYFKDSLGW
: . ..: :: ::.
XP_011 PKGQKGDP--GEP--GPAGLKGEAGEMGLSGLPGADGLKGEKGESASDSLQESLAQLIVE
340 350 360 370 380 390
>--
initn: 728 init1: 389 opt: 465 Z-score: 234.4 bits: 52.9 E(85289): 2.6e-06
Smith-Waterman score: 492; 44.4% identity (57.0% similar) in 207 aa overlap (99-295:351-537)
70 80 90 100 110 120
pF1KE2 GGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRP
: : : .: :::: : :::::: .
XP_011 GELGLPGAPGIDGEKGPKGQKGDPGEPGPAGLKGEAGEMGLSGLPGADGLKGEKGESASD
330 340 350 360 370 380
130 140 150 160 170 180
pF1KE2 GRKGRPGPPGV-PGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGS
. . . : :: ::: ::: :: ::: : .:: :: :..::::.
XP_011 SLQESLAQLIVEPGPPGP---PGPPGP---------MGLQGIQGP---KGLDGAKGEKGA
390 400 410 420
190 200 210 220 230 240
pF1KE2 RGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGV
::.: : : : ::. :. : ::: : ::::. : :: :. : :...:.::. ::
XP_011 SGERGPSGLPGPVGPPGLIGLPGTKGEKGRPGEPGLDGFPGPRGEKGDRSERGEKGERGV
430 440 450 460 470 480
250 260 270 280 290
pF1KE2 MGPPGKPGPSGQPGRPGPPG---PPPAGQLIMGPKGERGFPG--PPGR----CLCGPTMN
::. : .:: :.::::: : :. . : :.:: :: :.: : ::
XP_011 ---PGRKGVKGQKGEPGPPGLDQPCPVENPTCG--GRRGAPGWRGPARGNGPCPAGPDGL
490 500 510 520 530 540
300 310 320 330 340 350
pF1KE2 VNNPSYGESVYGPSSPRVPVIFVVNNQEELERLNTQNAIAFRRDQRSLYFKDSLGWLPIQ
XP_011 PVPGCWHK
>>XP_016883155 (OMIM: 120270,600969,603932) PREDICTED: c (486 aa)
initn: 1041 init1: 589 opt: 672 Z-score: 328.0 bits: 70.0 E(85289): 1.6e-11
Smith-Waterman score: 674; 41.2% identity (55.8% similar) in 301 aa overlap (56-317:140-431)
30 40 50 60 70 80
pF1KE2 FINSVLPISAALPSLDQKKRGGHKACCLLTPPPPPLFPPPFFRGGRSPLLSPDMKNLMLE
:: : .: . : .: : ... :
XP_016 GPPGLGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPG--LPGPPGPPGPPGHPGVLPE
110 120 130 140 150 160
90 100 110 120 130 140
pF1KE2 LETS-QSPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPG
:. : : :. :::::: : ::. : :: :::.::.:. :.:: ::::: :.::
XP_016 GATDLQCP----SICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPG
170 180 190 200 210 220
150 160 170 180 190
pF1KE2 PIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPG---------SRGEKGS---RGEKG
.: ::.: :: : :: ::.:::.: .: :: .:::.: :: ::
XP_016 SVGLQGPRGLRGLPGPLGP---PGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKG
230 240 250 260 270 280
200 210 220 230
pF1KE2 DLG------------PKGEKGFPG------FPGMLGQKGEMGPKGEPGIAGHRGPTGRPG
::: :.:: :.:: ::. ::::: : .: :: : : : ::
XP_016 DLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPG
290 300 310 320 330 340
240 250 260 270 280
pF1KE2 KRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP----PAGQL-IMGPKGERGFPGPPG
. :..:.::. : : :. ::::.:: :: : : ::. : : .: :: ::
XP_016 RAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPG
350 360 370 380 390 400
290 300 310 320 330 340
pF1KE2 -RCLCGPTMNVNNPSYG--ESVYGPSSPRVPVIFVVNNQEELERLNTQNAIAFRRDQRSL
: . : ....:. ... : . : :
XP_016 VRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSG
410 420 430 440 450 460
350 360 370 380 390 400
pF1KE2 YFKDSLGWLPIQLTPFYPVDYTADQHGTCGDGLLQPGEECDDGNSDVGDDCIRCHRAYCG
XP_016 LVGPKGEEVTLRGDGGNASPRLPPPC
470 480
>>XP_011526847 (OMIM: 120270,600969,603932) PREDICTED: c (552 aa)
initn: 1613 init1: 586 opt: 672 Z-score: 327.3 bits: 70.1 E(85289): 1.7e-11
Smith-Waterman score: 674; 41.2% identity (55.8% similar) in 301 aa overlap (56-317:140-431)
30 40 50 60 70 80
pF1KE2 FINSVLPISAALPSLDQKKRGGHKACCLLTPPPPPLFPPPFFRGGRSPLLSPDMKNLMLE
:: : .: . : .: : ... :
XP_011 GPPGLGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPG--LPGPPGPPGPPGHPGVLPE
110 120 130 140 150 160
90 100 110 120 130 140
pF1KE2 LETS-QSPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPG
:. : : :. :::::: : ::. : :: :::.::.:. :.:: ::::: :.::
XP_011 GATDLQCP----SICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPG
170 180 190 200 210 220
150 160 170 180 190
pF1KE2 PIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPG---------SRGEKGS---RGEKG
.: ::.: :: : :: ::.:::.: .: :: .:::.: :: ::
XP_011 SVGLQGPRGLRGLPGPLGP---PGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKG
230 240 250 260 270 280
200 210 220 230
pF1KE2 DLG------------PKGEKGFPG------FPGMLGQKGEMGPKGEPGIAGHRGPTGRPG
::: :.:: :.:: ::. ::::: : .: :: : : : ::
XP_011 DLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPG
290 300 310 320 330 340
240 250 260 270 280
pF1KE2 KRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPP----PAGQL-IMGPKGERGFPGPPG
. :..:.::. : : :. ::::.:: :: : : ::. : : .: :: ::
XP_011 RAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPG
350 360 370 380 390 400
290 300 310 320 330 340
pF1KE2 -RCLCGPTMNVNNPSYG--ESVYGPSSPRVPVIFVVNNQEELERLNTQNAIAFRRDQRSL
: . : ....:. ... : . : :
XP_011 VRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSG
410 420 430 440 450 460
350 360 370 380 390 400
pF1KE2 YFKDSLGWLPIQLTPFYPVDYTADQHGTCGDGLLQPGEECDDGNSDVGDDCIRCHRAYCG
XP_011 LVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEA
470 480 490 500 510 520
>>XP_011526344 (OMIM: 120216) PREDICTED: collagen alpha- (1744 aa)
initn: 609 init1: 609 opt: 684 Z-score: 326.8 bits: 71.7 E(85289): 1.8e-11
Smith-Waterman score: 695; 44.3% identity (60.6% similar) in 264 aa overlap (56-315:597-837)
30 40 50 60 70 80
pF1KE2 FINSVLPISAALPSLDQKKRGGHKACCLLTPPPPPLFPPPFFRGGRSPLLSPDMKNLMLE
: : :. : ::. .: : . ..
XP_011 FGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGP---RGSPGPTGRPGVTGI---
570 580 590 600 610 620
90 100 110 120 130 140
pF1KE2 LETSQSPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPG-
. .: .:..: :: ::: : : :. : : .: .: ::.:: :: ::.::.::
XP_011 ---DGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGS
630 640 650 660 670
150 160 170 180 190 200
pF1KE2 --PIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGF
:.: :: ::: :::: .: ::: :: :::: :: ::. :..: : :::::
XP_011 DGPLGHPGHEGPTGEKG---AQGPPGSAGP---PGYPGPRGVKGTSGNRGLQGEKGEKGE
680 690 700 710 720 730
210 220 230 240 250 260
pF1KE2 PGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGR
::::. ::..: ::. : : :: :. : .: .:: :..: ::::. : .:. :
XP_011 DGFPGF---KGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGV
740 750 760 770 780
270 280 290 300 310 320
pF1KE2 PGPPGPPPAGQLIMGPKGERGFPGPPGRC-LCGPTMNVNNPSYGESVYGPSSPRVPVIFV
:: :: : :. :::: ::::: : : . ....:. :. :: . :
XP_011 PGLPGYP--GR--PGPKGSIGFPGPLGPIGEKGKSGKTGQPGL-EGERGPPGSRGERGQP
790 800 810 820 830 840
330 340 350 360 370 380
pF1KE2 VNNQEELERLNTQNAIAFRRDQRSLYFKDSLGWLPIQLTPFYPVDYTADQHGTCGDGLLQ
XP_011 GATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGEL
850 860 870 880 890 900
>--
initn: 1014 init1: 553 opt: 596 Z-score: 287.3 bits: 64.3 E(85289): 2.9e-09
Smith-Waterman score: 652; 41.2% identity (55.6% similar) in 277 aa overlap (95-343:1254-1528)
70 80 90 100 110 120
pF1KE2 PFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGE
.::.: : :: :::: :: .: : ::
XP_011 KGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGE
1230 1240 1250 1260 1270 1280
130 140 150 160 170 180
pF1KE2 LGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGE
: :: : :::::. : :: : :: .:: :. : : : :..: : : :: :
XP_011 KGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGP
1290 1300 1310 1320 1330 1340
190 200 210 220 230
pF1KE2 KGSRGEKGDLGPKGEKGFPG---FPGMLGQKGEMGPKGE------PGIAGHRGPTGRPGK
:.:: : .::.: .:.:: ::.:: :.::: : ::. : :: :. :.
XP_011 MGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGH
1350 1360 1370 1380 1390 1400
240 250 260 270
pF1KE2 ---------RGKQGQKGDSGVMGPPGKPGPSGQPGRPGP------PGPPP-AGQLIMGPK
:. :.:::.:. : : :::.:.:: ::: :::: :: : : :
XP_011 IGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPL--GQK
1410 1420 1430 1440 1450 1460
280 290 300 310 320 330
pF1KE2 GERGFPGPPG-RCLCGPTMNVNNPSYGESVYGPSSPR--VPVIFVVNNQEELERLNTQNA
: .: :: : : ::. . :. ..: : ::: . : . : : . ..
XP_011 GSKGSPGSMGPRGDTGPAGPPGPPGAPAELHGLRRRRRFVPVPLPVVEGGLEEVLASLTS
1470 1480 1490 1500 1510 1520
340 350 360 370 380 390
pF1KE2 IAFRRDQRSLYFKDSLGWLPIQLTPFYPVDYTADQHGTCGDGLLQPGEECDDGNSDVGDD
.... .:
XP_011 LSLELEQLRRPPGTAERPGLVCHELHRNHPHLPDGEYWIDPNQGCARDSFRVFCNFTAGG
1530 1540 1550 1560 1570 1580
>--
initn: 539 init1: 539 opt: 596 Z-score: 287.3 bits: 64.3 E(85289): 2.9e-09
Smith-Waterman score: 680; 44.7% identity (58.7% similar) in 264 aa overlap (96-317:928-1181)
70 80 90 100 110 120
pF1KE2 FFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPG---LPGKTGPKGEK
: :: ::::: :::: ::: : .: :
XP_011 GQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAK
900 910 920 930 940 950
130 140 150 160 170
pF1KE2 GELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGD------LGMMGLPGSRGPMG--
:::: :: :. :: :. :.::: : :: :: : ::: .: : :: :::.:
XP_011 GELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPA
960 970 980 990 1000 1010
180 190 200 210 220
pF1KE2 ----------SKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIA
:.: : :.::::::.: :: :. :.:: : :: : ::.:: :
XP_011 GGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEG--
1020 1030 1040 1050 1060 1070
230 240 250 260 270
pF1KE2 GHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGP--------PPA--GQL
.: .: ::..:..:.:::.: :::.:: : :.::::: ::. ::
XP_011 -DKGDVGAPGHKGSKGDKGDAG---PPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQK
1080 1090 1100 1110 1120 1130
280 290 300 310 320
pF1KE2 ----------IMGPKGERGFPGPPGRCLCGPTMNVNNPSYG-ESVYGPSSPRVPVIFVVN
..:: : .:.:::::. : . .:. :.: ... :: .:. :
XP_011 GDDGVRGFVGVIGPPGLQGLPGPPGE--KGEVGDVG--SMGPHGAPGPRGPQGPTGSEGT
1140 1150 1160 1170 1180
330 340 350 360 370 380
pF1KE2 NQEELERLNTQNAIAFRRDQRSLYFKDSLGWLPIQLTPFYPVDYTADQHGTCGDGLLQPG
XP_011 PGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGP
1190 1200 1210 1220 1230 1240
>--
initn: 1046 init1: 387 opt: 467 Z-score: 229.3 bits: 53.6 E(85289): 4.9e-06
Smith-Waterman score: 500; 41.9% identity (55.2% similar) in 203 aa overlap (92-273:393-593)
70 80 90 100 110 120
pF1KE2 FPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGKTGPKGE
: : : :: :: ::::.:: :: :
XP_011 TQFQIFPGAGEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGP
370 380 390 400 410 420
130 140 150 160
pF1KE2 KGELGRPGRKGRPGPPG-VPGMPGPIGWPGPEGPR-----------------GEKGDLGM
: : :: : :::: : :: .. . .:: . :: :
XP_011 AGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGP
430 440 450 460 470 480
170 180 190 200 210 220
pF1KE2 MGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGI
.:: : ::.: :.:: .::.:..: .: : .: .: :: : .:. : : .: ::
XP_011 VGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGD
490 500 510 520 530 540
230 240 250 260 270 280
pF1KE2 AG---HRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKG
.: :: : :: :..::.:: : .: :: :: .:. : ::::: .::
XP_011 TGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGP--TGQAGEPGPR
550 560 570 580 590 600
290 300 310 320 330 340
pF1KE2 ERGFPGPPGRCLCGPTMNVNNPSYGESVYGPSSPRVPVIFVVNNQEELERLNTQNAIAFR
XP_011 GLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTP
610 620 630 640 650 660
>>NP_056534 (OMIM: 120216) collagen alpha-3(V) chain pre (1745 aa)
initn: 609 init1: 609 opt: 684 Z-score: 326.8 bits: 71.7 E(85289): 1.8e-11
Smith-Waterman score: 695; 44.3% identity (60.6% similar) in 264 aa overlap (56-315:598-838)
30 40 50 60 70 80
pF1KE2 FINSVLPISAALPSLDQKKRGGHKACCLLTPPPPPLFPPPFFRGGRSPLLSPDMKNLMLE
: : :. : ::. .: : . ..
NP_056 FGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGP---RGSPGPTGRPGVTGI---
570 580 590 600 610 620
90 100 110 120 130 140
pF1KE2 LETSQSPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPG-
. .: .:..: :: ::: : : :. : : .: .: ::.:: :: ::.::.::
NP_056 ---DGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGS
630 640 650 660 670
150 160 170 180 190 200
pF1KE2 --PIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGF
:.: :: ::: :::: .: ::: :: :::: :: ::. :..: : :::::
NP_056 DGPLGHPGHEGPTGEKG---AQGPPGSAGP---PGYPGPRGVKGTSGNRGLQGEKGEKGE
680 690 700 710 720 730
210 220 230 240 250 260
pF1KE2 PGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGR
::::. ::..: ::. : : :: :. : .: .:: :..: ::::. : .:. :
NP_056 DGFPGF---KGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGV
740 750 760 770 780
270 280 290 300 310 320
pF1KE2 PGPPGPPPAGQLIMGPKGERGFPGPPGRC-LCGPTMNVNNPSYGESVYGPSSPRVPVIFV
:: :: : :. :::: ::::: : : . ....:. :. :: . :
NP_056 PGLPGYP--GR--PGPKGSIGFPGPLGPIGEKGKSGKTGQPGL-EGERGPPGSRGERGQP
790 800 810 820 830 840
330 340 350 360 370 380
pF1KE2 VNNQEELERLNTQNAIAFRRDQRSLYFKDSLGWLPIQLTPFYPVDYTADQHGTCGDGLLQ
NP_056 GATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGEL
850 860 870 880 890 900
>--
initn: 1014 init1: 553 opt: 596 Z-score: 287.3 bits: 64.3 E(85289): 2.9e-09
Smith-Waterman score: 652; 41.2% identity (55.6% similar) in 277 aa overlap (95-343:1255-1529)
70 80 90 100 110 120
pF1KE2 PFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGKTGPKGEKGE
.::.: : :: :::: :: .: : ::
NP_056 KGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGE
1230 1240 1250 1260 1270 1280
130 140 150 160 170 180
pF1KE2 LGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGE
: :: : :::::. : :: : :: .:: :. : : : :..: : : :: :
NP_056 KGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGP
1290 1300 1310 1320 1330 1340
190 200 210 220 230
pF1KE2 KGSRGEKGDLGPKGEKGFPG---FPGMLGQKGEMGPKGE------PGIAGHRGPTGRPGK
:.:: : .::.: .:.:: ::.:: :.::: : ::. : :: :. :.
NP_056 MGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGH
1350 1360 1370 1380 1390 1400
240 250 260 270
pF1KE2 ---------RGKQGQKGDSGVMGPPGKPGPSGQPGRPGP------PGPPP-AGQLIMGPK
:. :.:::.:. : : :::.:.:: ::: :::: :: : : :
NP_056 IGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPL--GQK
1410 1420 1430 1440 1450 1460
280 290 300 310 320 330
pF1KE2 GERGFPGPPG-RCLCGPTMNVNNPSYGESVYGPSSPR--VPVIFVVNNQEELERLNTQNA
: .: :: : : ::. . :. ..: : ::: . : . : : . ..
NP_056 GSKGSPGSMGPRGDTGPAGPPGPPGAPAELHGLRRRRRFVPVPLPVVEGGLEEVLASLTS
1470 1480 1490 1500 1510 1520
340 350 360 370 380 390
pF1KE2 IAFRRDQRSLYFKDSLGWLPIQLTPFYPVDYTADQHGTCGDGLLQPGEECDDGNSDVGDD
.... .:
NP_056 LSLELEQLRRPPGTAERPGLVCHELHRNHPHLPDGEYWIDPNQGCARDSFRVFCNFTAGG
1530 1540 1550 1560 1570 1580
>--
initn: 539 init1: 539 opt: 596 Z-score: 287.3 bits: 64.3 E(85289): 2.9e-09
Smith-Waterman score: 680; 44.7% identity (58.7% similar) in 264 aa overlap (96-317:929-1182)
70 80 90 100 110 120
pF1KE2 FFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPG---LPGKTGPKGEK
: :: ::::: :::: ::: : .: :
NP_056 GQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAK
900 910 920 930 940 950
130 140 150 160 170
pF1KE2 GELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGD------LGMMGLPGSRGPMG--
:::: :: :. :: :. :.::: : :: :: : ::: .: : :: :::.:
NP_056 GELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPA
960 970 980 990 1000 1010
180 190 200 210 220
pF1KE2 ----------SKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIA
:.: : :.::::::.: :: :. :.:: : :: : ::.:: :
NP_056 GGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEG--
1020 1030 1040 1050 1060 1070
230 240 250 260 270
pF1KE2 GHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGP--------PPA--GQL
.: .: ::..:..:.:::.: :::.:: : :.::::: ::. ::
NP_056 -DKGDVGAPGHKGSKGDKGDAG---PPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQK
1080 1090 1100 1110 1120 1130
280 290 300 310 320
pF1KE2 ----------IMGPKGERGFPGPPGRCLCGPTMNVNNPSYG-ESVYGPSSPRVPVIFVVN
..:: : .:.:::::. : . .:. :.: ... :: .:. :
NP_056 GDDGVRGFVGVIGPPGLQGLPGPPGE--KGEVGDVG--SMGPHGAPGPRGPQGPTGSEGT
1140 1150 1160 1170 1180
330 340 350 360 370 380
pF1KE2 NQEELERLNTQNAIAFRRDQRSLYFKDSLGWLPIQLTPFYPVDYTADQHGTCGDGLLQPG
NP_056 PGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGP
1190 1200 1210 1220 1230 1240
>--
initn: 1046 init1: 387 opt: 467 Z-score: 229.3 bits: 53.6 E(85289): 4.9e-06
Smith-Waterman score: 500; 41.9% identity (55.2% similar) in 203 aa overlap (92-273:394-594)
70 80 90 100 110 120
pF1KE2 FPPPFFRGGRSPLLSPDMKNLMLELETSQSPCMQGSLGSPGPPGPQGPPGLPGKTGPKGE
: : : :: :: ::::.:: :: :
NP_056 TQFQIFPGAGEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGP
370 380 390 400 410 420
130 140 150 160
pF1KE2 KGELGRPGRKGRPGPPG-VPGMPGPIGWPGPEGPR-----------------GEKGDLGM
: : :: : :::: : :: .. . .:: . :: :
NP_056 AGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGP
430 440 450 460 470 480
170 180 190 200 210 220
pF1KE2 MGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGI
.:: : ::.: :.:: .::.:..: .: : .: .: :: : .:. : : .: ::
NP_056 VGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGD
490 500 510 520 530 540
230 240 250 260 270 280
pF1KE2 AG---HRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGRPGPPGPPPAGQLIMGPKG
.: :: : :: :..::.:: : .: :: :: .:. : ::::: .::
NP_056 TGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGP--TGQAGEPGPR
550 560 570 580 590 600
290 300 310 320 330 340
pF1KE2 ERGFPGPPGRCLCGPTMNVNNPSYGESVYGPSSPRVPVIFVVNNQEELERLNTQNAIAFR
NP_056 GLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTP
610 620 630 640 650 660
455 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 19:56:25 2016 done: Mon Nov 7 19:56:27 2016
Total Scan time: 8.700 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]