Result of FASTA (omim) for
pFN21AE2433
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2433, 1304 aa
1>>>pF1KE2433 1304 - 1304 aa - 1304 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.4142+/-0.000551; mu= -1.0647+/- 0.034
mean_var=287.8638+/-58.239, 0's: 0 Z-trim(115.6): 23 B-trim: 44 in 2/54
Lambda= 0.075593
statistics sampled from 26162 (26181) to 26162 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.646), E-opt: 0.2 (0.307), width: 16
Scan time: 15.840
The best scores are: opt bits E(85289)
NP_036565 (OMIM: 605590,614286) splicing factor 3B (1304) 8685 962.4 0
NP_001295753 (OMIM: 605590,614286) splicing factor ( 154) 929 115.9 2.3e-25
NP_001005526 (OMIM: 605590,614286) splicing factor ( 144) 921 115.0 3.9e-25
>>NP_036565 (OMIM: 605590,614286) splicing factor 3B sub (1304 aa)
initn: 8685 init1: 8685 opt: 8685 Z-score: 5134.7 bits: 962.4 E(85289): 0
Smith-Waterman score: 8685; 100.0% identity (100.0% similar) in 1304 aa overlap (1-1304:1-1304)
10 20 30 40 50 60
pF1KE2 MAKIAKTHEDIEAQIREIQGKKAALDEAQGVGLDSTGYYDQEIYGGSDSRFAGYVTSIAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MAKIAKTHEDIEAQIREIQGKKAALDEAQGVGLDSTGYYDQEIYGGSDSRFAGYVTSIAA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 TELEDDDDDYSSSTSLLGQKKPGYHAPVALLNDIPQSTEQYDPFAEHRPPKIADREDEYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 TELEDDDDDYSSSTSLLGQKKPGYHAPVALLNDIPQSTEQYDPFAEHRPPKIADREDEYK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 KHRRTMIISPERLDPFADGGKTPDPKMNARTYMDVMREQHLTKEEREIRQQLAEKAKAGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KHRRTMIISPERLDPFADGGKTPDPKMNARTYMDVMREQHLTKEEREIRQQLAEKAKAGE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 LKVVNGAAASQPPSKRKRRWDQTADQTPGATPKKLSSWDQAETPGHTPSLRWDETPGRAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LKVVNGAAASQPPSKRKRRWDQTADQTPGATPKKLSSWDQAETPGHTPSLRWDETPGRAK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GSETPGATPGSKIWDPTPSHTPAGAATPGRGDTPGHATPGHGGATSSARKNRWDETPKTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GSETPGATPGSKIWDPTPSHTPAGAATPGRGDTPGHATPGHGGATSSARKNRWDETPKTE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 RDTPGHGSGWAETPRTDRGGDSIGETPTPGASKRKSRWDETPASQMGGSTPVLTPGKTPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 RDTPGHGSGWAETPRTDRGGDSIGETPTPGASKRKSRWDETPASQMGGSTPVLTPGKTPI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 GTPAMNMATPTPGHIMSMTPEQLQAWRWEREIDERNRPLSDEELDAMFPEGYKVLPPPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GTPAMNMATPTPGHIMSMTPEQLQAWRWEREIDERNRPLSDEELDAMFPEGYKVLPPPAG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 YVPIRTPARKLTATPTPLGGMTGFHMQTEDRTMKSVNDQPSGNLPFLKPDDIQYFDKLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 YVPIRTPARKLTATPTPLGGMTGFHMQTEDRTMKSVNDQPSGNLPFLKPDDIQYFDKLLV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 DVDESTLSPEEQKERKIMKLLLKIKNGTPPMRKAALRQITDKAREFGAGPLFNQILPLLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 DVDESTLSPEEQKERKIMKLLLKIKNGTPPMRKAALRQITDKAREFGAGPLFNQILPLLM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 SPTLEDQERHLLVKVIDRILYKLDDLVRPYVHKILVVIEPLLIDEDYYARVEGREIISNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SPTLEDQERHLLVKVIDRILYKLDDLVRPYVHKILVVIEPLLIDEDYYARVEGREIISNL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 AKAAGLATMISTMRPDIDNMDEYVRNTTARAFAVVASALGIPSLLPFLKAVCKSKKSWQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 AKAAGLATMISTMRPDIDNMDEYVRNTTARAFAVVASALGIPSLLPFLKAVCKSKKSWQA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 RHTGIKIVQQIAILMGCAILPHLRSLVEIIEHGLVDEQQKVRTISALAIAALAEAATPYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 RHTGIKIVQQIAILMGCAILPHLRSLVEIIEHGLVDEQQKVRTISALAIAALAEAATPYG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 IESFDSVLKPLWKGIRQHRGKGLAAFLKAIGYLIPLMDAEYANYYTREVMLILIREFQSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 IESFDSVLKPLWKGIRQHRGKGLAAFLKAIGYLIPLMDAEYANYYTREVMLILIREFQSP
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 DEEMKKIVLKVVKQCCGTDGVEANYIKTEILPPFFKHFWQHRMALDRRNYRQLVDTTVEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 DEEMKKIVLKVVKQCCGTDGVEANYIKTEILPPFFKHFWQHRMALDRRNYRQLVDTTVEL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 ANKVGAAEIISRIVDDLKDEAEQYRKMVMETIEKIMGNLGAADIDHKLEEQLIDGILYAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 ANKVGAAEIISRIVDDLKDEAEQYRKMVMETIEKIMGNLGAADIDHKLEEQLIDGILYAF
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 QEQTTEDSVMLNGFGTVVNALGKRVKPYLPQICGTVLWRLNNKSAKVRQQAADLISRTAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 QEQTTEDSVMLNGFGTVVNALGKRVKPYLPQICGTVLWRLNNKSAKVRQQAADLISRTAV
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 VMKTCQEEKLMGHLGVVLYEYLGEEYPEVLGSILGALKAIVNVIGMHKMTPPIKDLLPRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 VMKTCQEEKLMGHLGVVLYEYLGEEYPEVLGSILGALKAIVNVIGMHKMTPPIKDLLPRL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 TPILKNRHEKVQENCIDLVGRIADRGAEYVSAREWMRICFELLELLKAHKKAIRRATVNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 TPILKNRHEKVQENCIDLVGRIADRGAEYVSAREWMRICFELLELLKAHKKAIRRATVNT
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 FGYIAKAIGPHDVLATLLNNLKVQERQNRVCTTVAIAIVAETCSPFTVLPALMNEYRVPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 FGYIAKAIGPHDVLATLLNNLKVQERQNRVCTTVAIAIVAETCSPFTVLPALMNEYRVPE
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 LNVQNGVLKSLSFLFEYIGEMGKDYIYAVTPLLEDALMDRDLVHRQTASAVVQHMSLGVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LNVQNGVLKSLSFLFEYIGEMGKDYIYAVTPLLEDALMDRDLVHRQTASAVVQHMSLGVY
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 GFGCEDSLNHLLNYVWPNVFETSPHVIQAVMGALEGLRVAIGPCRMLQYCLQGLFHPARK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GFGCEDSLNHLLNYVWPNVFETSPHVIQAVMGALEGLRVAIGPCRMLQYCLQGLFHPARK
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300
pF1KE2 VRDVYWKIYNSIYIGSQDALIAHYPRIYNDDKNTYIRYELDYIL
::::::::::::::::::::::::::::::::::::::::::::
NP_036 VRDVYWKIYNSIYIGSQDALIAHYPRIYNDDKNTYIRYELDYIL
1270 1280 1290 1300
>>NP_001295753 (OMIM: 605590,614286) splicing factor 3B (154 aa)
initn: 987 init1: 929 opt: 929 Z-score: 576.5 bits: 115.9 E(85289): 2.3e-25
Smith-Waterman score: 929; 97.9% identity (99.3% similar) in 143 aa overlap (1-143:1-143)
10 20 30 40 50 60
pF1KE2 MAKIAKTHEDIEAQIREIQGKKAALDEAQGVGLDSTGYYDQEIYGGSDSRFAGYVTSIAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAKIAKTHEDIEAQIREIQGKKAALDEAQGVGLDSTGYYDQEIYGGSDSRFAGYVTSIAA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 TELEDDDDDYSSSTSLLGQKKPGYHAPVALLNDIPQSTEQYDPFAEHRPPKIADREDEYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TELEDDDDDYSSSTSLLGQKKPGYHAPVALLNDIPQSTEQYDPFAEHRPPKIADREDEYK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 KHRRTMIISPERLDPFADGGKTPDPKMNARTYMDVMREQHLTKEEREIRQQLAEKAKAGE
:::::::::::::::::::.. :
NP_001 KHRRTMIISPERLDPFADGNSFPLFYKYSEIYLY
130 140 150
>>NP_001005526 (OMIM: 605590,614286) splicing factor 3B (144 aa)
initn: 921 init1: 921 opt: 921 Z-score: 572.2 bits: 115.0 E(85289): 3.9e-25
Smith-Waterman score: 921; 100.0% identity (100.0% similar) in 139 aa overlap (1-139:1-139)
10 20 30 40 50 60
pF1KE2 MAKIAKTHEDIEAQIREIQGKKAALDEAQGVGLDSTGYYDQEIYGGSDSRFAGYVTSIAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAKIAKTHEDIEAQIREIQGKKAALDEAQGVGLDSTGYYDQEIYGGSDSRFAGYVTSIAA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 TELEDDDDDYSSSTSLLGQKKPGYHAPVALLNDIPQSTEQYDPFAEHRPPKIADREDEYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TELEDDDDDYSSSTSLLGQKKPGYHAPVALLNDIPQSTEQYDPFAEHRPPKIADREDEYK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 KHRRTMIISPERLDPFADGGKTPDPKMNARTYMDVMREQHLTKEEREIRQQLAEKAKAGE
:::::::::::::::::::
NP_001 KHRRTMIISPERLDPFADGFYSAA
130 140
1304 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 20:14:04 2016 done: Mon Nov 7 20:14:07 2016
Total Scan time: 15.840 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]