Result of FASTA (omim) for
pFN21AE2404
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2404, 361 aa
1>>>pF1KE2404 361 - 361 aa - 361 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7842+/-0.000315; mu= 19.4827+/- 0.020
mean_var=62.8835+/-12.634, 0's: 0 Z-trim(115.8): 30 B-trim: 0 in 0/54
Lambda= 0.161736
statistics sampled from 26430 (26448) to 26430 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.691), E-opt: 0.2 (0.31), width: 16
Scan time: 8.710
The best scores are: opt bits E(85289)
NP_542388 (OMIM: 607810) radical S-adenosyl methio ( 361) 2462 582.9 3.9e-166
XP_011508716 (OMIM: 607810) PREDICTED: radical S-a ( 361) 2462 582.9 3.9e-166
XP_011508717 (OMIM: 607810) PREDICTED: radical S-a ( 293) 1675 399.2 6.2e-111
NP_005934 (OMIM: 252150,603707) molybdenum cofacto ( 385) 136 40.1 0.0097
NP_001068566 (OMIM: 252150,603707) molybdenum cofa ( 385) 136 40.1 0.0097
>>NP_542388 (OMIM: 607810) radical S-adenosyl methionine (361 aa)
initn: 2462 init1: 2462 opt: 2462 Z-score: 3103.7 bits: 582.9 E(85289): 3.9e-166
Smith-Waterman score: 2462; 99.7% identity (99.7% similar) in 361 aa overlap (1-361:1-361)
10 20 30 40 50 60
pF1KE2 MWVLTPAAFAGKLLSVFRQPLSSLWRSLVPLFCWLRATFWLRATKRRKQQLVLRGPDETK
::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::
NP_542 MWVLTPAAFAGKLLSVFRQPLSSLWRSLVPLFCWLRATFWLLATKRRKQQLVLRGPDETK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 EEEEDPPLPTTPTSVNYHFTRQCNYKCGFCFHTAKTSFVLPLEEAKRGLLLLKEAGMEKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 EEEEDPPLPTTPTSVNYHFTRQCNYKCGFCFHTAKTSFVLPLEEAKRGLLLLKEAGMEKI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 NFSGGEPFLQDRGEYLGKLVRFCKVELRLPSVSIVSNGSLIRERWFQNYGEYLDILAISC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 NFSGGEPFLQDRGEYLGKLVRFCKVELRLPSVSIVSNGSLIRERWFQNYGEYLDILAISC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 DSFDEEVNVLIGRGQGKKNHVENLQKLRRWCRDYRVAFKINSVINRFNVEEDMTEQIKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 DSFDEEVNVLIGRGQGKKNHVENLQKLRRWCRDYRVAFKINSVINRFNVEEDMTEQIKAL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 NPVRWKVFQCLLIEGENCGEDALREAERFVIGDEEFERFLERHKEVSCLVPESNQKMKDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 NPVRWKVFQCLLIEGENCGEDALREAERFVIGDEEFERFLERHKEVSCLVPESNQKMKDS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 YLILDEYMRFLNCRKGRKDPSKSILDVGVEEAIKFSGFDEKMFLKRGGKYIWSKADLKLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 YLILDEYMRFLNCRKGRKDPSKSILDVGVEEAIKFSGFDEKMFLKRGGKYIWSKADLKLD
310 320 330 340 350 360
pF1KE2 W
:
NP_542 W
>>XP_011508716 (OMIM: 607810) PREDICTED: radical S-adeno (361 aa)
initn: 2462 init1: 2462 opt: 2462 Z-score: 3103.7 bits: 582.9 E(85289): 3.9e-166
Smith-Waterman score: 2462; 99.7% identity (99.7% similar) in 361 aa overlap (1-361:1-361)
10 20 30 40 50 60
pF1KE2 MWVLTPAAFAGKLLSVFRQPLSSLWRSLVPLFCWLRATFWLRATKRRKQQLVLRGPDETK
::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::
XP_011 MWVLTPAAFAGKLLSVFRQPLSSLWRSLVPLFCWLRATFWLLATKRRKQQLVLRGPDETK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 EEEEDPPLPTTPTSVNYHFTRQCNYKCGFCFHTAKTSFVLPLEEAKRGLLLLKEAGMEKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEEEDPPLPTTPTSVNYHFTRQCNYKCGFCFHTAKTSFVLPLEEAKRGLLLLKEAGMEKI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 NFSGGEPFLQDRGEYLGKLVRFCKVELRLPSVSIVSNGSLIRERWFQNYGEYLDILAISC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NFSGGEPFLQDRGEYLGKLVRFCKVELRLPSVSIVSNGSLIRERWFQNYGEYLDILAISC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 DSFDEEVNVLIGRGQGKKNHVENLQKLRRWCRDYRVAFKINSVINRFNVEEDMTEQIKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSFDEEVNVLIGRGQGKKNHVENLQKLRRWCRDYRVAFKINSVINRFNVEEDMTEQIKAL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 NPVRWKVFQCLLIEGENCGEDALREAERFVIGDEEFERFLERHKEVSCLVPESNQKMKDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPVRWKVFQCLLIEGENCGEDALREAERFVIGDEEFERFLERHKEVSCLVPESNQKMKDS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 YLILDEYMRFLNCRKGRKDPSKSILDVGVEEAIKFSGFDEKMFLKRGGKYIWSKADLKLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLILDEYMRFLNCRKGRKDPSKSILDVGVEEAIKFSGFDEKMFLKRGGKYIWSKADLKLD
310 320 330 340 350 360
pF1KE2 W
:
XP_011 W
>>XP_011508717 (OMIM: 607810) PREDICTED: radical S-adeno (293 aa)
initn: 1675 init1: 1675 opt: 1675 Z-score: 2112.5 bits: 399.2 E(85289): 6.2e-111
Smith-Waterman score: 1675; 98.8% identity (99.2% similar) in 249 aa overlap (113-361:45-293)
90 100 110 120 130 140
pF1KE2 CNYKCGFCFHTAKTSFVLPLEEAKRGLLLLKEAGMEKINFSGGEPFLQDRGEYLGKLVRF
. :::::::::::::::::::::::::::
XP_011 PRGPRCAAPRACAVPRRRLPGLTPNEAPRRRPQGMEKINFSGGEPFLQDRGEYLGKLVRF
20 30 40 50 60 70
150 160 170 180 190 200
pF1KE2 CKVELRLPSVSIVSNGSLIRERWFQNYGEYLDILAISCDSFDEEVNVLIGRGQGKKNHVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CKVELRLPSVSIVSNGSLIRERWFQNYGEYLDILAISCDSFDEEVNVLIGRGQGKKNHVE
80 90 100 110 120 130
210 220 230 240 250 260
pF1KE2 NLQKLRRWCRDYRVAFKINSVINRFNVEEDMTEQIKALNPVRWKVFQCLLIEGENCGEDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLQKLRRWCRDYRVAFKINSVINRFNVEEDMTEQIKALNPVRWKVFQCLLIEGENCGEDA
140 150 160 170 180 190
270 280 290 300 310 320
pF1KE2 LREAERFVIGDEEFERFLERHKEVSCLVPESNQKMKDSYLILDEYMRFLNCRKGRKDPSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LREAERFVIGDEEFERFLERHKEVSCLVPESNQKMKDSYLILDEYMRFLNCRKGRKDPSK
200 210 220 230 240 250
330 340 350 360
pF1KE2 SILDVGVEEAIKFSGFDEKMFLKRGGKYIWSKADLKLDW
:::::::::::::::::::::::::::::::::::::::
XP_011 SILDVGVEEAIKFSGFDEKMFLKRGGKYIWSKADLKLDW
260 270 280 290
>>NP_005934 (OMIM: 252150,603707) molybdenum cofactor bi (385 aa)
initn: 64 init1: 64 opt: 136 Z-score: 170.1 bits: 40.1 E(85289): 0.0097
Smith-Waterman score: 136; 25.9% identity (59.4% similar) in 170 aa overlap (79-240:76-235)
50 60 70 80 90 100
pF1KE2 QQLVLRGPDETKEEEEDPPLPTTPTSVNYHFTRQCNYKCGFCFH------TAKTSFVLPL
.:..:: .: .:. : :....
NP_005 RRQFLREHAAPFSAFLTDSFGRQHSYLRISLTEKCNLRCQYCMPEEGVPLTPKANLLTTE
50 60 70 80 90 100
110 120 130 140 150 160
pF1KE2 EEAKRGLLLLKEAGMEKINFSGGEPFLQDRGEYLGKLVRFCKVELRLPSVSIVSNG-SLI
: . :..:: :..:: ..::::.. : . . .... ..: : ......:: .:
NP_005 EILTLARLFVKE-GIDKIRLTGGEPLI--RPDVVDIVAQLQRLE-GLRTIGVTTNGINLA
110 120 130 140 150 160
170 180 190 200 210 220
pF1KE2 RER-WFQNYGEYLDILAISCDSFDEEVNVLIGRGQGKKNHVENLQKLRRWCRDYRVAFKI
: .:. : :. . :: :.. .: : .: .. .:...: . . :.
NP_005 RLLPQLQKAG--LSAINISLDTLVPAKFEFIVRRKGFHKVMEGIHKAIELGYN---PVKV
170 180 190 200 210
230 240 250 260 270 280
pF1KE2 NSVINRFNVEEDMTEQIKALNPVRWKVFQCLLIEGENCGEDALREAERFVIGDEEFERFL
: :. : ...:: .. ::
NP_005 NCVVMR-GLNEDELLDFAALTEGLPLDVRFIEYMPFDGNKWNFKKMVSYKEMLDTVRQQW
220 230 240 250 260 270
>>NP_001068566 (OMIM: 252150,603707) molybdenum cofactor (385 aa)
initn: 64 init1: 64 opt: 136 Z-score: 170.1 bits: 40.1 E(85289): 0.0097
Smith-Waterman score: 136; 25.9% identity (59.4% similar) in 170 aa overlap (79-240:76-235)
50 60 70 80 90 100
pF1KE2 QQLVLRGPDETKEEEEDPPLPTTPTSVNYHFTRQCNYKCGFCFH------TAKTSFVLPL
.:..:: .: .:. : :....
NP_001 RRQFLREHAAPFSAFLTDSFGRQHSYLRISLTEKCNLRCQYCMPEEGVPLTPKANLLTTE
50 60 70 80 90 100
110 120 130 140 150 160
pF1KE2 EEAKRGLLLLKEAGMEKINFSGGEPFLQDRGEYLGKLVRFCKVELRLPSVSIVSNG-SLI
: . :..:: :..:: ..::::.. : . . .... ..: : ......:: .:
NP_001 EILTLARLFVKE-GIDKIRLTGGEPLI--RPDVVDIVAQLQRLE-GLRTIGVTTNGINLA
110 120 130 140 150 160
170 180 190 200 210 220
pF1KE2 RER-WFQNYGEYLDILAISCDSFDEEVNVLIGRGQGKKNHVENLQKLRRWCRDYRVAFKI
: .:. : :. . :: :.. .: : .: .. .:...: . . :.
NP_001 RLLPQLQKAG--LSAINISLDTLVPAKFEFIVRRKGFHKVMEGIHKAIELGYN---PVKV
170 180 190 200 210
230 240 250 260 270 280
pF1KE2 NSVINRFNVEEDMTEQIKALNPVRWKVFQCLLIEGENCGEDALREAERFVIGDEEFERFL
: :. : ...:: .. ::
NP_001 NCVVMR-GLNEDELLDFAALTEGLPLDVRFIEYMPFDGNKWNFKKMVSYKEMLDTVRQQW
220 230 240 250 260 270
361 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 09:18:09 2016 done: Sun Nov 6 09:18:10 2016
Total Scan time: 8.710 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]