Result of FASTA (omim) for
pFN21AE2366
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2366, 466 aa
1>>>pF1KE2366 466 - 466 aa - 466 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.4473+/-0.000414; mu= 12.2023+/- 0.026
mean_var=114.8944+/-24.299, 0's: 0 Z-trim(113.9): 165 B-trim: 353 in 1/55
Lambda= 0.119653
statistics sampled from 23216 (23420) to 23216 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.637), E-opt: 0.2 (0.275), width: 16
Scan time: 7.470
The best scores are: opt bits E(85289)
NP_001294936 (OMIM: 605984) polycomb protein EED i ( 466) 3253 573.0 5.9e-163
XP_011543632 (OMIM: 605984) PREDICTED: polycomb pr ( 428) 2957 521.9 1.3e-147
XP_011543633 (OMIM: 605984) PREDICTED: polycomb pr ( 415) 2792 493.4 4.9e-139
XP_016874001 (OMIM: 605984) PREDICTED: polycomb pr ( 403) 2224 395.3 1.6e-109
NP_003788 (OMIM: 605984) polycomb protein EED isof ( 441) 2224 395.4 1.7e-109
XP_016874002 (OMIM: 605984) PREDICTED: polycomb pr ( 323) 1655 297.1 4.9e-80
NP_001317263 (OMIM: 605984) polycomb protein EED i ( 361) 1655 297.1 5.3e-80
NP_004362 (OMIM: 601924,616414) coatomer subunit a (1224) 188 44.3 0.0023
NP_001091868 (OMIM: 601924,616414) coatomer subuni (1233) 188 44.3 0.0023
NP_001186706 (OMIM: 614784,615973) POC1 centriolar ( 436) 181 42.7 0.0024
NP_758440 (OMIM: 614784,615973) POC1 centriolar pr ( 478) 181 42.7 0.0026
XP_016861593 (OMIM: 614783,614813) PREDICTED: POC1 ( 321) 172 41.0 0.0056
NP_001155052 (OMIM: 614783,614813) POC1 centriolar ( 359) 172 41.1 0.0061
NP_001155053 (OMIM: 614783,614813) POC1 centriolar ( 369) 172 41.1 0.0062
NP_056241 (OMIM: 614783,614813) POC1 centriolar pr ( 407) 172 41.1 0.0067
>>NP_001294936 (OMIM: 605984) polycomb protein EED isofo (466 aa)
initn: 3253 init1: 3253 opt: 3253 Z-score: 3046.6 bits: 573.0 E(85289): 5.9e-163
Smith-Waterman score: 3253; 100.0% identity (100.0% similar) in 466 aa overlap (1-466:1-466)
10 20 30 40 50 60
pF1KE2 MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 NAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 QCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 TRDIHRNYVDCVRWLGDLILSKSGRAILHSHQQCMRDPVSPNLRQHLSCENAIVCWKPGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TRDIHRNYVDCVRWLGDLILSKSGRAILHSHQQCMRDPVSPNLRQHLSCENAIVCWKPGK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 MEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVED
370 380 390 400 410 420
430 440 450 460
pF1KE2 PHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRLR
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRLR
430 440 450 460
>>XP_011543632 (OMIM: 605984) PREDICTED: polycomb protei (428 aa)
initn: 2957 init1: 2957 opt: 2957 Z-score: 2770.9 bits: 521.9 E(85289): 1.3e-147
Smith-Waterman score: 2957; 100.0% identity (100.0% similar) in 424 aa overlap (1-424:1-424)
10 20 30 40 50 60
pF1KE2 MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 NAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 QCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 TRDIHRNYVDCVRWLGDLILSKSGRAILHSHQQCMRDPVSPNLRQHLSCENAIVCWKPGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRDIHRNYVDCVRWLGDLILSKSGRAILHSHQQCMRDPVSPNLRQHLSCENAIVCWKPGK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 MEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVED
370 380 390 400 410 420
430 440 450 460
pF1KE2 PHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRLR
::::
XP_011 PHKANRDH
>>XP_011543633 (OMIM: 605984) PREDICTED: polycomb protei (415 aa)
initn: 2792 init1: 2792 opt: 2792 Z-score: 2617.2 bits: 493.4 E(85289): 4.9e-139
Smith-Waterman score: 2792; 100.0% identity (100.0% similar) in 400 aa overlap (1-400:1-400)
10 20 30 40 50 60
pF1KE2 MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 NAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 QCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 TRDIHRNYVDCVRWLGDLILSKSGRAILHSHQQCMRDPVSPNLRQHLSCENAIVCWKPGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRDIHRNYVDCVRWLGDLILSKSGRAILHSHQQCMRDPVSPNLRQHLSCENAIVCWKPGK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 MEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVED
::::::::::::::::::::::::::::::::::::::::
XP_011 MEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKEYKTQRNSQEHRGWN
370 380 390 400 410
430 440 450 460
pF1KE2 PHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRLR
>>XP_016874001 (OMIM: 605984) PREDICTED: polycomb protei (403 aa)
initn: 2223 init1: 2223 opt: 2224 Z-score: 2087.5 bits: 395.3 E(85289): 1.6e-109
Smith-Waterman score: 2717; 94.1% identity (94.1% similar) in 424 aa overlap (1-424:1-399)
10 20 30 40 50 60
pF1KE2 MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 NAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 QCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 TRDIHRNYVDCVRWLGDLILSKSGRAILHSHQQCMRDPVSPNLRQHLSCENAIVCWKPGK
::::::::::::::::::::::: ::::::::::::
XP_016 TRDIHRNYVDCVRWLGDLILSKS-------------------------CENAIVCWKPGK
310 320 330
370 380 390 400 410 420
pF1KE2 MEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVED
340 350 360 370 380 390
430 440 450 460
pF1KE2 PHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRLR
::::
XP_016 PHKANRDH
400
>>NP_003788 (OMIM: 605984) polycomb protein EED isoform (441 aa)
initn: 2223 init1: 2223 opt: 2224 Z-score: 2086.9 bits: 395.4 E(85289): 1.7e-109
Smith-Waterman score: 3013; 94.6% identity (94.6% similar) in 466 aa overlap (1-466:1-441)
10 20 30 40 50 60
pF1KE2 MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 NAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 QCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 TRDIHRNYVDCVRWLGDLILSKSGRAILHSHQQCMRDPVSPNLRQHLSCENAIVCWKPGK
::::::::::::::::::::::: ::::::::::::
NP_003 TRDIHRNYVDCVRWLGDLILSKS-------------------------CENAIVCWKPGK
310 320 330
370 380 390 400 410 420
pF1KE2 MEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVED
340 350 360 370 380 390
430 440 450 460
pF1KE2 PHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRLR
::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRLR
400 410 420 430 440
>>XP_016874002 (OMIM: 605984) PREDICTED: polycomb protei (323 aa)
initn: 2200 init1: 1655 opt: 1655 Z-score: 1557.9 bits: 297.1 E(85289): 4.9e-80
Smith-Waterman score: 1994; 75.2% identity (75.2% similar) in 424 aa overlap (1-424:1-319)
10 20 30 40 50 60
pF1KE2 MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 NAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 QCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFS
::
XP_016 SA----------------------------------------------------------
310 320 330 340 350 360
pF1KE2 TRDIHRNYVDCVRWLGDLILSKSGRAILHSHQQCMRDPVSPNLRQHLSCENAIVCWKPGK
:::::::::::::
XP_016 -----------------------------------------------SCENAIVCWKPGK
250
370 380 390 400 410 420
pF1KE2 MEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVED
260 270 280 290 300 310
430 440 450 460
pF1KE2 PHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRLR
::::
XP_016 PHKANRDH
320
>>NP_001317263 (OMIM: 605984) polycomb protein EED isofo (361 aa)
initn: 2496 init1: 1655 opt: 1655 Z-score: 1557.3 bits: 297.1 E(85289): 5.3e-80
Smith-Waterman score: 2290; 77.5% identity (77.5% similar) in 466 aa overlap (1-466:1-361)
10 20 30 40 50 60
pF1KE2 MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 NAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 QCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFS
::
NP_001 SA----------------------------------------------------------
310 320 330 340 350 360
pF1KE2 TRDIHRNYVDCVRWLGDLILSKSGRAILHSHQQCMRDPVSPNLRQHLSCENAIVCWKPGK
:::::::::::::
NP_001 -----------------------------------------------SCENAIVCWKPGK
250
370 380 390 400 410 420
pF1KE2 MEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEDDIDKIKPSESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVED
260 270 280 290 300 310
430 440 450 460
pF1KE2 PHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRLR
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHKAKCTTLTHHKCGAAIRQTSFSRDSSILIAVCDDASIWRWDRLR
320 330 340 350 360
>>NP_004362 (OMIM: 601924,616414) coatomer subunit alpha (1224 aa)
initn: 124 init1: 75 opt: 188 Z-score: 181.3 bits: 44.3 E(85289): 0.0023
Smith-Waterman score: 188; 28.0% identity (60.2% similar) in 118 aa overlap (155-272:58-171)
130 140 150 160 170 180
pF1KE2 ECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIK
: . ..::.. .:. :.. : .:.
NP_004 LHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLF
30 40 50 60 70 80
190 200 210 220 230 240
pF1KE2 HYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADY
.:: . : :: . : .::.: :...:.:: :. : : .. :: :. :..
NP_004 TLLGHLDYIRTTFFHHEYP-WILSASDDQTIRVWNWQSRTCVCVL---TGHNHYVMCAQF
90 100 110 120 130 140
250 260 270 280 290 300
pF1KE2 DLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDI
. ..: ..:.....: :.. : :
NP_004 HPTEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLEG
150 160 170 180 190 200
>>NP_001091868 (OMIM: 601924,616414) coatomer subunit al (1233 aa)
initn: 124 init1: 75 opt: 188 Z-score: 181.3 bits: 44.3 E(85289): 0.0023
Smith-Waterman score: 188; 28.0% identity (60.2% similar) in 118 aa overlap (155-272:58-171)
130 140 150 160 170 180
pF1KE2 ECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIK
: . ..::.. .:. :.. : .:.
NP_001 LHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLF
30 40 50 60 70 80
190 200 210 220 230 240
pF1KE2 HYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADY
.:: . : :: . : .::.: :...:.:: :. : : .. :: :. :..
NP_001 TLLGHLDYIRTTFFHHEYP-WILSASDDQTIRVWNWQSRTCVCVL---TGHNHYVMCAQF
90 100 110 120 130 140
250 260 270 280 290 300
pF1KE2 DLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDI
. ..: ..:.....: :.. : :
NP_001 HPTEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLEG
150 160 170 180 190 200
>>NP_001186706 (OMIM: 614784,615973) POC1 centriolar pro (436 aa)
initn: 166 init1: 82 opt: 181 Z-score: 181.0 bits: 42.7 E(85289): 0.0024
Smith-Waterman score: 181; 28.6% identity (61.6% similar) in 112 aa overlap (155-266:151-258)
130 140 150 160 170 180
pF1KE2 ECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIK
: : : .: ::: ... . . . ..
NP_001 SEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 HYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADY
:: :....: ..::: . : :...:.: .:.. .. :. ..:: :.....
NP_001 HYQVHSGGVNCISFHP-SGNYLITASSDGTLKILDLLEGRLIYT---LQGHTGPVFTVSF
190 200 210 220 230
250 260 270 280 290 300
pF1KE2 DLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFSTRDI
. :: . : : : .. ::: :
NP_001 SKGGELFASGGADTQVLLWRTNFDELHCKGLTKRNLKRLHFDSPPHLLDIYPRTPHPHEE
240 250 260 270 280 290
466 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 19:59:36 2016 done: Sun Nov 6 19:59:37 2016
Total Scan time: 7.470 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]