Result of FASTA (omim) for
pFN21AE2352
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2352, 311 aa
1>>>pF1KE2352 311 - 311 aa - 311 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9376+/-0.000321; mu= 18.4550+/- 0.020
mean_var=76.4998+/-15.878, 0's: 0 Z-trim(115.8): 129 B-trim: 0 in 0/51
Lambda= 0.146637
statistics sampled from 26448 (26589) to 26448 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.694), E-opt: 0.2 (0.312), width: 16
Scan time: 5.980
The best scores are: opt bits E(85289)
NP_001307581 (OMIM: 188370) T-cell surface glycopr ( 316) 2145 463.0 3.6e-130
NP_001754 (OMIM: 188370) T-cell surface glycoprote ( 327) 2145 463.0 3.7e-130
NP_001755 (OMIM: 188360) T-cell surface glycoprote ( 333) 1314 287.2 3.1e-77
NP_001756 (OMIM: 188340) T-cell surface glycoprote ( 333) 1267 277.2 3.1e-74
NP_001036048 (OMIM: 188411) T-cell surface glycopr ( 376) 1213 265.9 9.2e-71
NP_112155 (OMIM: 188411) T-cell surface glycoprote ( 388) 1213 265.9 9.4e-71
XP_005245636 (OMIM: 188340) PREDICTED: T-cell surf ( 346) 1152 252.9 6.7e-67
XP_011508427 (OMIM: 188410) PREDICTED: antigen-pre ( 335) 1143 251.0 2.4e-66
NP_001757 (OMIM: 188410) antigen-presenting glycop ( 335) 1143 251.0 2.4e-66
XP_011508436 (OMIM: 188411) PREDICTED: T-cell surf ( 290) 1012 223.2 4.8e-58
NP_001036049 (OMIM: 188411) T-cell surface glycopr ( 290) 1012 223.2 4.8e-58
NP_001172043 (OMIM: 188411) T-cell surface glycopr ( 289) 932 206.3 6e-53
XP_011508429 (OMIM: 188410) PREDICTED: antigen-pre ( 231) 929 205.6 7.9e-53
XP_006711684 (OMIM: 188410) PREDICTED: antigen-pre ( 231) 929 205.6 7.9e-53
XP_005245640 (OMIM: 188410) PREDICTED: antigen-pre ( 231) 929 205.6 7.9e-53
XP_011508421 (OMIM: 188360) PREDICTED: T-cell surf ( 278) 907 201.0 2.3e-51
NP_001036050 (OMIM: 188411) T-cell surface glycopr ( 321) 888 197.0 4.1e-50
XP_011508435 (OMIM: 188411) PREDICTED: T-cell surf ( 333) 888 197.1 4.2e-50
NP_001172044 (OMIM: 188411) T-cell surface glycopr ( 286) 629 142.2 1.2e-33
NP_001172036 (OMIM: 188411) T-cell surface glycopr ( 298) 629 142.2 1.2e-33
XP_016858275 (OMIM: 188360) PREDICTED: T-cell surf ( 220) 616 139.4 6.5e-33
NP_001036051 (OMIM: 188411) T-cell surface glycopr ( 187) 612 138.4 1e-32
NP_001172041 (OMIM: 188411) T-cell surface glycopr ( 199) 612 138.5 1.1e-32
XP_016858274 (OMIM: 188360) PREDICTED: T-cell surf ( 239) 609 137.9 1.9e-32
XP_016858273 (OMIM: 188360) PREDICTED: T-cell surf ( 269) 608 137.7 2.4e-32
NP_001306074 (OMIM: 188410) antigen-presenting gly ( 242) 511 117.2 3.4e-26
NP_001036052 (OMIM: 188411) T-cell surface glycopr ( 101) 411 95.7 4.2e-20
NP_001522 (OMIM: 600764) major histocompatibility ( 341) 393 92.4 1.4e-18
XP_011507765 (OMIM: 600764) PREDICTED: major histo ( 254) 357 84.6 2.3e-16
NP_002107 (OMIM: 142800,608579) HLA class I histoc ( 365) 347 82.6 1.3e-15
NP_001176 (OMIM: 194460) zinc-alpha-2-glycoprotein ( 298) 336 80.2 5.5e-15
NP_002118 (OMIM: 142871,600807) HLA class I histoc ( 338) 330 79.0 1.5e-14
XP_016866305 (OMIM: 142871,600807) PREDICTED: HLA ( 343) 330 79.0 1.5e-14
NP_001229687 (OMIM: 142800,608579) HLA class I his ( 365) 325 78.0 3.2e-14
NP_001129491 (OMIM: 601437) IgG receptor FcRn larg ( 365) 319 76.7 7.8e-14
NP_004098 (OMIM: 601437) IgG receptor FcRn large s ( 365) 319 76.7 7.8e-14
NP_005507 (OMIM: 143010) HLA class I histocompatib ( 358) 316 76.1 1.2e-13
XP_016866298 (OMIM: 143010) PREDICTED: HLA class I ( 359) 316 76.1 1.2e-13
XP_016866296 (OMIM: 143010) PREDICTED: HLA class I ( 399) 316 76.1 1.3e-13
XP_016866297 (OMIM: 143010) PREDICTED: HLA class I ( 399) 316 76.1 1.3e-13
NP_002108 (OMIM: 142840,177900,609423) HLA class I ( 366) 310 74.8 2.9e-13
NP_001229971 (OMIM: 142840,177900,609423) HLA clas ( 366) 308 74.4 3.9e-13
NP_001172037 (OMIM: 188411) T-cell surface glycopr ( 231) 304 73.4 5e-13
NP_620578 (OMIM: 104300,176100,176200,235200,61263 ( 325) 304 73.5 6.4e-13
NP_001287678 (OMIM: 104300,176100,176200,235200,61 ( 337) 304 73.5 6.6e-13
XP_011512845 (OMIM: 104300,176100,176200,235200,61 ( 348) 304 73.5 6.8e-13
NP_000401 (OMIM: 104300,176100,176200,235200,61263 ( 348) 304 73.5 6.8e-13
XP_011512866 (OMIM: 143110) PREDICTED: HLA class I ( 343) 299 72.5 1.4e-12
NP_061823 (OMIM: 143110) HLA class I histocompatib ( 346) 299 72.5 1.4e-12
XP_016866302 (OMIM: 143110) PREDICTED: HLA class I ( 388) 299 72.5 1.5e-12
>>NP_001307581 (OMIM: 188370) T-cell surface glycoprotei (316 aa)
initn: 2145 init1: 2145 opt: 2145 Z-score: 2457.9 bits: 463.0 E(85289): 3.6e-130
Smith-Waterman score: 2145; 99.3% identity (99.3% similar) in 307 aa overlap (5-311:10-316)
10 20 30 40 50
pF1KE2 MWNWLKEPLSFHVIWIASFYNHSWKQNLVSGWLSDLQTHTWDSNSSTIVFLWPWS
::::::::: ::::::::::::::::::::::::::::::::::::: :::
NP_001 MFAFGGATGLKEPLSFHVTWIASFYNHSWKQNLVSGWLSDLQTHTWDSNSSTIVFLCPWS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 RGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPFEIQVTGGCELHSGKVSGSFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPFEIQVTGGCELHSGKVSGSFL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 QLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHENDITHNLLSDTCPRFILGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHENDITHNLLSDTCPRFILGLL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE2 DAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPKPVWVMWMRGEQEQQGTQRGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPKPVWVMWMRGEQEQQGTQRGD
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE2 ILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIVLYWEHHSSVGFIILAVIVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIVLYWEHHSSVGFIILAVIVPL
250 260 270 280 290 300
300 310
pF1KE2 LLLIGLALWFRKRCFC
::::::::::::::::
NP_001 LLLIGLALWFRKRCFC
310
>>NP_001754 (OMIM: 188370) T-cell surface glycoprotein C (327 aa)
initn: 2145 init1: 2145 opt: 2145 Z-score: 2457.7 bits: 463.0 E(85289): 3.7e-130
Smith-Waterman score: 2145; 99.3% identity (99.3% similar) in 307 aa overlap (5-311:21-327)
10 20 30 40
pF1KE2 MWNWLKEPLSFHVIWIASFYNHSWKQNLVSGWLSDLQTHTWDSN
::::::::: ::::::::::::::::::::::::::::::
NP_001 MLFLLLPLLAVLPGDGNADGLKEPLSFHVTWIASFYNHSWKQNLVSGWLSDLQTHTWDSN
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE2 SSTIVFLWPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPFEIQVTGGCE
::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSTIVFLCPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPFEIQVTGGCE
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE2 LHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHENDITHNLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHENDITHNLLS
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE2 DTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPKPVWVMWMRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPKPVWVMWMRG
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE2 EQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIVLYWEHHSSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIVLYWEHHSSV
250 260 270 280 290 300
290 300 310
pF1KE2 GFIILAVIVPLLLLIGLALWFRKRCFC
:::::::::::::::::::::::::::
NP_001 GFIILAVIVPLLLLIGLALWFRKRCFC
310 320
>>NP_001755 (OMIM: 188360) T-cell surface glycoprotein C (333 aa)
initn: 1338 init1: 1270 opt: 1314 Z-score: 1507.5 bits: 287.2 E(85289): 3.1e-77
Smith-Waterman score: 1314; 62.6% identity (80.8% similar) in 302 aa overlap (8-308:25-326)
10 20 30 40
pF1KE2 MWNWLKEPLSFHVIWIASFYNHSWKQNLVSGWLSDLQTHTWDS
: ::::: .:: : .: :. ::::.::: : :::
NP_001 MLLLPFQLLAVLFPGGNSEHAFQGPTSFHVIQTSSFTNSTWAQTQGSGWLDDLQIHGWDS
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE2 NSSTIVFLWPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPFEIQVTGGC
.:.: .:: :::.::::..: ::: .::. . . .. .: ..:..:::::: .::
NP_001 DSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYPFEIQGIAGC
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE2 ELHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHENDITHNLL
::::: . :::. : : ::.: .: : .: : .:. :..:: .. : : . .. ::
NP_001 ELHSGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALIIQYQGIMETVRILL
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE2 SDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPKPVWVMWMR
.::::..::.:.:::: :::::::::::: :::::::.:::::::::::::::::::::
NP_001 YETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQLVCHVSGFYPKPVWVMWMR
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE2 GEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIVLYWEHHSS
::::::::: :::::.:. ::::::::.:: :::: :::::::::::::::.:::.. .:
NP_001 GEQEQQGTQLGDILPNANWTWYLRATLDVADGEAAGLSCRVKHSSLEGQDIILYWRNPTS
250 260 270 280 290 300
290 300 310
pF1KE2 VGFIILAVIVP-LLLLIGLALWFRKRCFC
.: :.::.::: ::::. ::::. .:
NP_001 IGSIVLAIIVPSLLLLLCLALWYMRRRSYQNIP
310 320 330
>>NP_001756 (OMIM: 188340) T-cell surface glycoprotein C (333 aa)
initn: 1277 init1: 748 opt: 1267 Z-score: 1453.8 bits: 277.2 E(85289): 3.1e-74
Smith-Waterman score: 1267; 59.2% identity (82.0% similar) in 306 aa overlap (6-309:23-327)
10 20 30 40
pF1KE2 MWNWLKEPLSFHVIWIASFYNHSWKQNLVSGWLSDLQTHTWDS
.: .::::: : :: :.:: .. ::::..:::: :::
NP_001 MLFLQFLLLALLLPGGDNADASQEHVSFHVIQIFSFVNQSWARGQGSGWLDELQTHGWDS
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE2 NSSTIVFLWPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPFEIQVTGGC
.:.::.:: ::.::::::: ..:: :::. . . :. .: . .::::.:: .::
NP_001 ESGTIIFLHNWSKGNFSNEELSDLELLFRFYLFGLTREIQDHASQDYSKYPFEVQVKAGC
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE2 ELHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHEN--DITHN
:::::: .:.:.:..: :..::::..:.: : :..:. :..::. :.:. . ..:
NP_001 ELHSGKSPEGFFQVAFNGLDLLSFQNTTWVPSPGCGSLAQSVCHLLNH-QYEGVTETVYN
130 140 150 160 170
170 180 190 200 210 220
pF1KE2 LLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPKPVWVMW
:. .:::::.:::::::: ...:::.:::::: :: : :.: ::::.:::::::::: :
NP_001 LIRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCHASGFYPKPVWVTW
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE2 MRGEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIVLYWEHH
::.:::: ::..:::::.:::::::.. ::::. : : :::::.:::: ::::.::: ::
NP_001 MRNEQEQLGTKHGDILPNADGTWYLQVILEVASEEPAGLSCRVRHSSLGGQDIILYWGHH
240 250 260 270 280 290
290 300 310
pF1KE2 SSVGFIILAVIVPLLLLIGLALWFRKRCFC
:...: :.:::::..:: :.:::.:.:
NP_001 FSMNWIALVVIVPLVILIVLVLWFKKHCSYQDIL
300 310 320 330
>>NP_001036048 (OMIM: 188411) T-cell surface glycoprotei (376 aa)
initn: 1210 init1: 854 opt: 1213 Z-score: 1391.4 bits: 265.9 E(85289): 9.2e-71
Smith-Waterman score: 1213; 58.6% identity (82.7% similar) in 295 aa overlap (6-299:32-323)
10 20 30
pF1KE2 MWNWLKEPLSFHVIWIASFYNHSWKQNLVSGWLSD
.: :::... .:: :::: .. ::::.:
NP_001 LLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLGD
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE2 LQTHTWDSNSSTIVFLWPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPF
:::: ::. .:: :: :::.::::..: :.:..::.. .. .. : ..:.::::
NP_001 LQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYPF
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE2 EIQVTGGCELHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHE
:::. .::.... .. ::..:::::::.:::. :: : : :: :...:::::.
NP_001 EIQILAGCRMNAPQI---FLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDI
130 140 150 160 170
160 170 180 190 200 210
pF1KE2 NDITHNLLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPK
..: ..::. :::::. ::..::...:.:.:::::::: :::::::.:::::::::::::
NP_001 KEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPK
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE2 PVWVMWMRGEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIV
:::::::::::::.::::::.::.:: ::::::::.::::::: :::::::::: :.:..
NP_001 PVWVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLI
240 250 260 270 280 290
280 290 300 310
pF1KE2 LYWEHHSSVGFII-LAVIVPLLLLIGLALWFRKRCFC
..: .: ..: :.::: :..:.
NP_001 IHWGGYSIFLILICLTVIVTLVILVVVDSRLKKQSPVFLMGANTQDTKNSRHQFCLAQVS
300 310 320 330 340 350
>>NP_112155 (OMIM: 188411) T-cell surface glycoprotein C (388 aa)
initn: 1210 init1: 854 opt: 1213 Z-score: 1391.2 bits: 265.9 E(85289): 9.4e-71
Smith-Waterman score: 1213; 58.6% identity (82.7% similar) in 295 aa overlap (6-299:32-323)
10 20 30
pF1KE2 MWNWLKEPLSFHVIWIASFYNHSWKQNLVSGWLSD
.: :::... .:: :::: .. ::::.:
NP_112 LLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLGD
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE2 LQTHTWDSNSSTIVFLWPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPF
:::: ::. .:: :: :::.::::..: :.:..::.. .. .. : ..:.::::
NP_112 LQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYPF
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE2 EIQVTGGCELHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHE
:::. .::.... .. ::..:::::::.:::. :: : : :: :...:::::.
NP_112 EIQILAGCRMNAPQI---FLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDI
130 140 150 160 170
160 170 180 190 200 210
pF1KE2 NDITHNLLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPK
..: ..::. :::::. ::..::...:.:.:::::::: :::::::.:::::::::::::
NP_112 KEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPK
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE2 PVWVMWMRGEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIV
:::::::::::::.::::::.::.:: ::::::::.::::::: :::::::::: :.:..
NP_112 PVWVMWMRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLI
240 250 260 270 280 290
280 290 300 310
pF1KE2 LYWEHHSSVGFII-LAVIVPLLLLIGLALWFRKRCFC
..: .: ..: :.::: :..:.
NP_112 IHWGGYSIFLILICLTVIVTLVILVVVDSRLKKQSSNKNILSPHTPSPVFLMGANTQDTK
300 310 320 330 340 350
>>XP_005245636 (OMIM: 188340) PREDICTED: T-cell surface (346 aa)
initn: 1162 init1: 633 opt: 1152 Z-score: 1322.1 bits: 252.9 E(85289): 6.7e-67
Smith-Waterman score: 1152; 59.2% identity (81.2% similar) in 277 aa overlap (6-280:23-298)
10 20 30 40
pF1KE2 MWNWLKEPLSFHVIWIASFYNHSWKQNLVSGWLSDLQTHTWDS
.: .::::: : :: :.:: .. ::::..:::: :::
XP_005 MLFLQFLLLALLLPGGDNADASQEHVSFHVIQIFSFVNQSWARGQGSGWLDELQTHGWDS
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE2 NSSTIVFLWPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPFEIQVTGGC
.:.::.:: ::.::::::: ..:: :::. . . :. .: . .::::.:: .::
XP_005 ESGTIIFLHNWSKGNFSNEELSDLELLFRFYLFGLTREIQDHASQDYSKYPFEVQVKAGC
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE2 ELHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHEN--DITHN
:::::: .:.:.:..: :..::::..:.: : :..:. :..::. :.:. . ..:
XP_005 ELHSGKSPEGFFQVAFNGLDLLSFQNTTWVPSPGCGSLAQSVCHLLNH-QYEGVTETVYN
130 140 150 160 170
170 180 190 200 210 220
pF1KE2 LLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPKPVWVMW
:. .:::::.:::::::: ...:::.:::::: :: : :.: ::::.:::::::::: :
XP_005 LIRSTCPRFLLGLLDAGKMYVHRQVRPEAWLSSRPSLGSGQLLLVCHASGFYPKPVWVTW
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE2 MRGEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIVLYWEHH
::.:::: ::..:::::.:::::::.. ::::. : : :::::.:::: ::::.::: :
XP_005 MRNEQEQLGTKHGDILPNADGTWYLQVILEVASEEPAGLSCRVRHSSLGGQDIILYWAHI
240 250 260 270 280 290
290 300 310
pF1KE2 SSVGFIILAVIVPLLLLIGLALWFRKRCFC
XP_005 RTSCETLPPDSPIVLRTQQPRSLVQYSDAIPSTLHLNCFSFCIINIC
300 310 320 330 340
>>XP_011508427 (OMIM: 188410) PREDICTED: antigen-present (335 aa)
initn: 1097 init1: 1097 opt: 1143 Z-score: 1312.0 bits: 251.0 E(85289): 2.4e-66
Smith-Waterman score: 1143; 52.1% identity (80.5% similar) in 313 aa overlap (2-308:16-328)
10 20 30 40
pF1KE2 MWNWLKEP---LSFHVIWIASFYNHSWKQNLVSGWLSDLQTHTWDS
:. . : . .. . :.:: : :: .. .::..::::.:..
XP_011 MGCLLFLLLWALLQAWGSAEVPQRLFPLRCLQISSFANSSWTRTDGLAWLGELQTHSWSN
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE2 NSSTIVFLWPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPFEIQVTGGC
.:.:. : :::.:.::...:. :. .::. . ....:. :.. ::.:.::..::
XP_011 DSDTVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRDVKEFAKMLRLSYPLELQVSAGC
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE2 ELHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHENDITHNLL
:.: :..:..:...:.::.:..:::..:: : : .. .::::.. . .. ::
XP_011 EVHPGNASNNFFHVAFQGKDILSFQGTSWEPTQEAPLWVNLAIQVLNQDKWTRETVQWLL
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE2 SDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPKPVWVMWMR
. :::.:. :::..::..:..::::.::::.:::::::.: ::::::::::::::: :::
XP_011 NGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVSGFYPKPVWVKWMR
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE2 GEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIVLYWE-HHS
::::::::: :::::.:: ::::::::.:.::::: ::::::::::::::::::: ..
XP_011 GEQEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSSLEGQDIVLYWGGSYT
250 260 270 280 290 300
290 300 310
pF1KE2 SVGFIILAVIVPLL--LLIGLALWFRKRCFC
:.:.: :::.. :: :..:.. :...
XP_011 SMGLIALAVLACLLFLLIVGFTSRFKRQTSYQGVL
310 320 330
>>NP_001757 (OMIM: 188410) antigen-presenting glycoprote (335 aa)
initn: 1097 init1: 1097 opt: 1143 Z-score: 1312.0 bits: 251.0 E(85289): 2.4e-66
Smith-Waterman score: 1143; 52.1% identity (80.5% similar) in 313 aa overlap (2-308:16-328)
10 20 30 40
pF1KE2 MWNWLKEP---LSFHVIWIASFYNHSWKQNLVSGWLSDLQTHTWDS
:. . : . .. . :.:: : :: .. .::..::::.:..
NP_001 MGCLLFLLLWALLQAWGSAEVPQRLFPLRCLQISSFANSSWTRTDGLAWLGELQTHSWSN
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE2 NSSTIVFLWPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPFEIQVTGGC
.:.:. : :::.:.::...:. :. .::. . ....:. :.. ::.:.::..::
NP_001 DSDTVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRDVKEFAKMLRLSYPLELQVSAGC
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE2 ELHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHENDITHNLL
:.: :..:..:...:.::.:..:::..:: : : .. .::::.. . .. ::
NP_001 EVHPGNASNNFFHVAFQGKDILSFQGTSWEPTQEAPLWVNLAIQVLNQDKWTRETVQWLL
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE2 SDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPKPVWVMWMR
. :::.:. :::..::..:..::::.::::.:::::::.: ::::::::::::::: :::
NP_001 NGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVSGFYPKPVWVKWMR
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE2 GEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIVLYWE-HHS
::::::::: :::::.:: ::::::::.:.::::: ::::::::::::::::::: ..
NP_001 GEQEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSSLEGQDIVLYWGGSYT
250 260 270 280 290 300
290 300 310
pF1KE2 SVGFIILAVIVPLL--LLIGLALWFRKRCFC
:.:.: :::.. :: :..:.. :...
NP_001 SMGLIALAVLACLLFLLIVGFTSRFKRQTSYQGVL
310 320 330
>>XP_011508436 (OMIM: 188411) PREDICTED: T-cell surface (290 aa)
initn: 1034 init1: 678 opt: 1012 Z-score: 1163.0 bits: 223.2 E(85289): 4.8e-58
Smith-Waterman score: 1012; 57.7% identity (82.6% similar) in 241 aa overlap (6-246:32-269)
10 20 30
pF1KE2 MWNWLKEPLSFHVIWIASFYNHSWKQNLVSGWLSD
.: :::... .:: :::: .. ::::.:
XP_011 LLLFLLFEGLCCPGENTAAPQALQSYHLAAEEQLSFRMLQTSSFANHSWAHSEGSGWLGD
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE2 LQTHTWDSNSSTIVFLWPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPF
:::: ::. .:: :: :::.::::..: :.:..::.. .. .. : ..:.::::
XP_011 LQTHGWDTVLGTIRFLKPWSHGNFSKQELKNLQSLFQLYFHSFIQIVQASAGQFQLEYPF
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE2 EIQVTGGCELHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHE
:::. .::.... .. ::..:::::::.:::. :: : : :: :...:::::.
XP_011 EIQILAGCRMNAPQI---FLNMAYQGSDFLSFQGISWEPSPGAGIRAQNICKVLNRYLDI
130 140 150 160 170
160 170 180 190 200 210
pF1KE2 NDITHNLLSDTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPK
..: ..::. :::::. ::..::...:.:.:::::::: :::::::.:::::::::::::
XP_011 KEILQSLLGHTCPRFLAGLMEAGESELKRKVKPEAWLSCGPSPGPGRLQLVCHVSGFYPK
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE2 PVWVMWMRGEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIV
:::::::::::::.::::::.::.:: ::..
XP_011 PVWVMWMRGEQEQRGTQRGDVLPNADETWWIFHLSHPDLFDCDSYPGHIGCS
240 250 260 270 280 290
280 290 300 310
pF1KE2 LYWEHHSSVGFIILAVIVPLLLLIGLALWFRKRCFC
311 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 22:26:23 2016 done: Sun Nov 6 22:26:24 2016
Total Scan time: 5.980 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]