Result of FASTA (omim) for
pFN21AE2323
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2323, 1708 aa
1>>>pF1KE2323 1708 - 1708 aa - 1708 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.5175+/-0.000479; mu= 17.5064+/- 0.030
mean_var=90.6127+/-18.426, 0's: 0 Z-trim(108.3): 73 B-trim: 11 in 1/56
Lambda= 0.134735
statistics sampled from 16333 (16394) to 16333 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.53), E-opt: 0.2 (0.192), width: 16
Scan time: 19.730
The best scores are: opt bits E(85289)
NP_689969 (OMIM: 609022) rapamycin-insensitive com (1708) 11198 2188.5 0
XP_016864801 (OMIM: 609022) PREDICTED: rapamycin-i (1692) 10999 2149.9 0
XP_006714526 (OMIM: 609022) PREDICTED: rapamycin-i (1670) 9580 1874.0 0
XP_016864804 (OMIM: 609022) PREDICTED: rapamycin-i (1423) 9378 1834.7 0
XP_011512307 (OMIM: 609022) PREDICTED: rapamycin-i (1694) 9004 1762.1 0
NP_001272368 (OMIM: 609022) rapamycin-insensitive (1732) 9004 1762.1 0
XP_016864800 (OMIM: 609022) PREDICTED: rapamycin-i (1716) 8805 1723.4 0
XP_016864802 (OMIM: 609022) PREDICTED: rapamycin-i (1679) 8666 1696.4 0
XP_011512308 (OMIM: 609022) PREDICTED: rapamycin-i (1669) 8586 1680.8 0
NP_001272369 (OMIM: 609022) rapamycin-insensitive (1385) 7760 1520.2 0
XP_016864803 (OMIM: 609022) PREDICTED: rapamycin-i (1447) 7184 1408.3 0
NP_001309300 (OMIM: 616991) mucin-21 isoform 3 pre ( 626) 172 45.1 0.0024
NP_001309299 (OMIM: 616991) mucin-21 isoform 2 pre ( 596) 164 43.5 0.0067
>>NP_689969 (OMIM: 609022) rapamycin-insensitive compani (1708 aa)
initn: 11198 init1: 11198 opt: 11198 Z-score: 11757.3 bits: 2188.5 E(85289): 0
Smith-Waterman score: 11198; 100.0% identity (100.0% similar) in 1708 aa overlap (1-1708:1-1708)
10 20 30 40 50 60
pF1KE2 MAAIGRGRSLKNLRVRGRNDSGEENVPLDLTREPSDNLREILQNVARLQGVSNMRKLGHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 MAAIGRGRSLKNLRVRGRNDSGEENVPLDLTREPSDNLREILQNVARLQGVSNMRKLGHL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 NNFTKLLCDIGHSEEKLGFHYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 NNFTKLLCDIGHSEEKLGFHYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 LKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVTNSLIAVGNDGLQER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 LKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVTNSLIAVGNDGLQER
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 DRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 DRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 RQYVRADVELERILAPYTDFHYRHSPDTAEGQLKEDREARFLASKMGIIATFRSWAGIIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 RQYVRADVELERILAPYTDFHYRHSPDTAEGQLKEDREARFLASKMGIIATFRSWAGIIN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 LCKPGNSGIQSLIGVLCIPNMEIRRGLLEVLYDIFRLPLPVVTEEFIEALLSVDPGRFQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 LCKPGNSGIQSLIGVLCIPNMEIRRGLLEVLYDIFRLPLPVVTEEFIEALLSVDPGRFQD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 SWRLSDGFVAAEAKTILPHRARSRPDLMDNYLALILSAFIRNGLLEGLVEVITNSDDHIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 SWRLSDGFVAAEAKTILPHRARSRPDLMDNYLALILSAFIRNGLLEGLVEVITNSDDHIS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 VRATILLGELLHMANTILPHSHSHHLHCLPTLMNMAASFDIPKEKRLRASAALNCLKRFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 VRATILLGELLHMANTILPHSHSHHLHCLPTLMNMAASFDIPKEKRLRASAALNCLKRFH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 EMKKRGPKPYSLHLDHIIQKAIATHQKRDQYLRVQKDIFILKDTEEALLINLRDSQVLQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 EMKKRGPKPYSLHLDHIIQKAIATHQKRDQYLRVQKDIFILKDTEEALLINLRDSQVLQH
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 KENLEWNWNLIGTILKWPNVNLRNYKDEQLHRFVRRLLYFYKPSSKLYANLDLDFAKAKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 KENLEWNWNLIGTILKWPNVNLRNYKDEQLHRFVRRLLYFYKPSSKLYANLDLDFAKAKQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 LTVVGCQFTEFLLESEEDGQGYLEDLVKDIVQWLNASSGMKPERSLQNNGLLTTLSQHYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 LTVVGCQFTEFLLESEEDGQGYLEDLVKDIVQWLNASSGMKPERSLQNNGLLTTLSQHYF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 LFIGTLSCHPHGVKMLEKCSVFQCLLNLCSLKNQDHLLKLTVSSLDYSRDGLARVILSKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 LFIGTLSCHPHGVKMLEKCSVFQCLLNLCSLKNQDHLLKLTVSSLDYSRDGLARVILSKI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 LTAATDACRLYATKHLRVLLRANVEFFNNWGIELLVTQLHDKNKTISSEALDILDEACED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 LTAATDACRLYATKHLRVLLRANVEFFNNWGIELLVTQLHDKNKTISSEALDILDEACED
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 KANLHALIQMKPALSHLGDKGLLLLLRFLSIPKGFSYLNERGYVAKQLEKWHREYNSKYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 KANLHALIQMKPALSHLGDKGLLLLLRFLSIPKGFSYLNERGYVAKQLEKWHREYNSKYV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 DLIEEQLNEALTTYRKPVDGDNYVRRSNQRLQRPHVYLPIHLYGQLVHHKTGCHLLEVQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 DLIEEQLNEALTTYRKPVDGDNYVRRSNQRLQRPHVYLPIHLYGQLVHHKTGCHLLEVQN
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 IITELCRNVRTPDLDKWEEIKKLKASLWALGNIGSSNWGLNLLQEENVIPDILKLAKQCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 IITELCRNVRTPDLDKWEEIKKLKASLWALGNIGSSNWGLNLLQEENVIPDILKLAKQCE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 VLSIRGTCVYVLGLIAKTKQGCDILKCHNWDAVRHSRKHLWPVVPDDVEQLCNELSSIPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 VLSIRGTCVYVLGLIAKTKQGCDILKCHNWDAVRHSRKHLWPVVPDDVEQLCNELSSIPS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 TLSLNSESTSSRHNSESESVPSSMFILEDDRFGSSSTSTFFLDINEDTEPTFYDRSGPIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 TLSLNSESTSSRHNSESESVPSSMFILEDDRFGSSSTSTFFLDINEDTEPTFYDRSGPIK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 DKNSFPFFASSKLVKNRILNSLTLPNKKHRSSSDPKGGKLSSESKTSNRRIRTLTEPSVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 DKNSFPFFASSKLVKNRILNSLTLPNKKHRSSSDPKGGKLSSESKTSNRRIRTLTEPSVD
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 FNHSDDFTPISTVQKTLQLETSFMGNKHIEDTGSTPSIGENDLKFTKNFGTENHRENTSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 FNHSDDFTPISTVQKTLQLETSFMGNKHIEDTGSTPSIGENDLKFTKNFGTENHRENTSR
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 ERLVVESSTSSHMKIRSQSFNTDTTTSGISSMSSSPSRETVGVDATTMDTDCGSMSTVVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 ERLVVESSTSSHMKIRSQSFNTDTTTSGISSMSSSPSRETVGVDATTMDTDCGSMSTVVS
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 TKTIKTSHYLTPQSNHLSLSKSNSVSLVPPGSSHTLPRRAQSLKAPSIATIKSLADCNFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 TKTIKTSHYLTPQSNHLSLSKSNSVSLVPPGSSHTLPRRAQSLKAPSIATIKSLADCNFS
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 YTSSRDAFGYATLKRLQQQRMHPSLSHSEALASPAKDVLFTDTITMKANSFESRLTPSRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 YTSSRDAFGYATLKRLQQQRMHPSLSHSEALASPAKDVLFTDTITMKANSFESRLTPSRF
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 MKALSYASLDKEDLLSPINQNTLQRSSSVRSMVSSATYGGSDDYIGLALPVDINDIFQVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 MKALSYASLDKEDLLSPINQNTLQRSSSVRSMVSSATYGGSDDYIGLALPVDINDIFQVK
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE2 DIPYFQTKNIPPHDDRGARAFAHDAGGLPSGTGGLVKNSFHLLRQQMSLTEIMNSIHSDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 DIPYFQTKNIPPHDDRGARAFAHDAGGLPSGTGGLVKNSFHLLRQQMSLTEIMNSIHSDA
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE2 SLFLESTEDTGLQEHTDDNCLYCVCIEILGFQPSNQLSAICSHSDFQDIPYSDWCEQTIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 SLFLESTEDTGLQEHTDDNCLYCVCIEILGFQPSNQLSAICSHSDFQDIPYSDWCEQTIH
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE2 NPLEVVPSKFSGISGCSDGVSQEGSASSTKSTELLLGVKTIPDDTPMCRILLRKEVLRLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 NPLEVVPSKFSGISGCSDGVSQEGSASSTKSTELLLGVKTIPDDTPMCRILLRKEVLRLV
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE2 INLSSSVSTKCHETGLLTIKEKYPQTFDDICLYSEVSHLLSHCTFRLPCRRFIQELFQDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 INLSSSVSTKCHETGLLTIKEKYPQTFDDICLYSEVSHLLSHCTFRLPCRRFIQELFQDV
1630 1640 1650 1660 1670 1680
1690 1700
pF1KE2 QFLQMHEEAEAVLATPPKQPIVDTSAES
::::::::::::::::::::::::::::
NP_689 QFLQMHEEAEAVLATPPKQPIVDTSAES
1690 1700
>>XP_016864801 (OMIM: 609022) PREDICTED: rapamycin-insen (1692 aa)
initn: 10999 init1: 10999 opt: 10999 Z-score: 11548.3 bits: 2149.9 E(85289): 0
Smith-Waterman score: 11049; 99.1% identity (99.1% similar) in 1708 aa overlap (1-1708:1-1692)
10 20 30 40 50 60
pF1KE2 MAAIGRGRSLKNLRVRGRNDSGEENVPLDLTREPSDNLREILQNVARLQGVSNMRKLGHL
:::::::::::::::: ::::::::::::::::::::::::::::
XP_016 MAAIGRGRSLKNLRVR----------------EPSDNLREILQNVARLQGVSNMRKLGHL
10 20 30 40
70 80 90 100 110 120
pF1KE2 NNFTKLLCDIGHSEEKLGFHYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNFTKLLCDIGHSEEKLGFHYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKV
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE2 LKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVTNSLIAVGNDGLQER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVTNSLIAVGNDGLQER
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE2 DRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKT
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE2 RQYVRADVELERILAPYTDFHYRHSPDTAEGQLKEDREARFLASKMGIIATFRSWAGIIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQYVRADVELERILAPYTDFHYRHSPDTAEGQLKEDREARFLASKMGIIATFRSWAGIIN
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE2 LCKPGNSGIQSLIGVLCIPNMEIRRGLLEVLYDIFRLPLPVVTEEFIEALLSVDPGRFQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LCKPGNSGIQSLIGVLCIPNMEIRRGLLEVLYDIFRLPLPVVTEEFIEALLSVDPGRFQD
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE2 SWRLSDGFVAAEAKTILPHRARSRPDLMDNYLALILSAFIRNGLLEGLVEVITNSDDHIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SWRLSDGFVAAEAKTILPHRARSRPDLMDNYLALILSAFIRNGLLEGLVEVITNSDDHIS
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE2 VRATILLGELLHMANTILPHSHSHHLHCLPTLMNMAASFDIPKEKRLRASAALNCLKRFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRATILLGELLHMANTILPHSHSHHLHCLPTLMNMAASFDIPKEKRLRASAALNCLKRFH
410 420 430 440 450 460
490 500 510 520 530 540
pF1KE2 EMKKRGPKPYSLHLDHIIQKAIATHQKRDQYLRVQKDIFILKDTEEALLINLRDSQVLQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EMKKRGPKPYSLHLDHIIQKAIATHQKRDQYLRVQKDIFILKDTEEALLINLRDSQVLQH
470 480 490 500 510 520
550 560 570 580 590 600
pF1KE2 KENLEWNWNLIGTILKWPNVNLRNYKDEQLHRFVRRLLYFYKPSSKLYANLDLDFAKAKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KENLEWNWNLIGTILKWPNVNLRNYKDEQLHRFVRRLLYFYKPSSKLYANLDLDFAKAKQ
530 540 550 560 570 580
610 620 630 640 650 660
pF1KE2 LTVVGCQFTEFLLESEEDGQGYLEDLVKDIVQWLNASSGMKPERSLQNNGLLTTLSQHYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTVVGCQFTEFLLESEEDGQGYLEDLVKDIVQWLNASSGMKPERSLQNNGLLTTLSQHYF
590 600 610 620 630 640
670 680 690 700 710 720
pF1KE2 LFIGTLSCHPHGVKMLEKCSVFQCLLNLCSLKNQDHLLKLTVSSLDYSRDGLARVILSKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFIGTLSCHPHGVKMLEKCSVFQCLLNLCSLKNQDHLLKLTVSSLDYSRDGLARVILSKI
650 660 670 680 690 700
730 740 750 760 770 780
pF1KE2 LTAATDACRLYATKHLRVLLRANVEFFNNWGIELLVTQLHDKNKTISSEALDILDEACED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTAATDACRLYATKHLRVLLRANVEFFNNWGIELLVTQLHDKNKTISSEALDILDEACED
710 720 730 740 750 760
790 800 810 820 830 840
pF1KE2 KANLHALIQMKPALSHLGDKGLLLLLRFLSIPKGFSYLNERGYVAKQLEKWHREYNSKYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KANLHALIQMKPALSHLGDKGLLLLLRFLSIPKGFSYLNERGYVAKQLEKWHREYNSKYV
770 780 790 800 810 820
850 860 870 880 890 900
pF1KE2 DLIEEQLNEALTTYRKPVDGDNYVRRSNQRLQRPHVYLPIHLYGQLVHHKTGCHLLEVQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLIEEQLNEALTTYRKPVDGDNYVRRSNQRLQRPHVYLPIHLYGQLVHHKTGCHLLEVQN
830 840 850 860 870 880
910 920 930 940 950 960
pF1KE2 IITELCRNVRTPDLDKWEEIKKLKASLWALGNIGSSNWGLNLLQEENVIPDILKLAKQCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IITELCRNVRTPDLDKWEEIKKLKASLWALGNIGSSNWGLNLLQEENVIPDILKLAKQCE
890 900 910 920 930 940
970 980 990 1000 1010 1020
pF1KE2 VLSIRGTCVYVLGLIAKTKQGCDILKCHNWDAVRHSRKHLWPVVPDDVEQLCNELSSIPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLSIRGTCVYVLGLIAKTKQGCDILKCHNWDAVRHSRKHLWPVVPDDVEQLCNELSSIPS
950 960 970 980 990 1000
1030 1040 1050 1060 1070 1080
pF1KE2 TLSLNSESTSSRHNSESESVPSSMFILEDDRFGSSSTSTFFLDINEDTEPTFYDRSGPIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLSLNSESTSSRHNSESESVPSSMFILEDDRFGSSSTSTFFLDINEDTEPTFYDRSGPIK
1010 1020 1030 1040 1050 1060
1090 1100 1110 1120 1130 1140
pF1KE2 DKNSFPFFASSKLVKNRILNSLTLPNKKHRSSSDPKGGKLSSESKTSNRRIRTLTEPSVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKNSFPFFASSKLVKNRILNSLTLPNKKHRSSSDPKGGKLSSESKTSNRRIRTLTEPSVD
1070 1080 1090 1100 1110 1120
1150 1160 1170 1180 1190 1200
pF1KE2 FNHSDDFTPISTVQKTLQLETSFMGNKHIEDTGSTPSIGENDLKFTKNFGTENHRENTSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FNHSDDFTPISTVQKTLQLETSFMGNKHIEDTGSTPSIGENDLKFTKNFGTENHRENTSR
1130 1140 1150 1160 1170 1180
1210 1220 1230 1240 1250 1260
pF1KE2 ERLVVESSTSSHMKIRSQSFNTDTTTSGISSMSSSPSRETVGVDATTMDTDCGSMSTVVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERLVVESSTSSHMKIRSQSFNTDTTTSGISSMSSSPSRETVGVDATTMDTDCGSMSTVVS
1190 1200 1210 1220 1230 1240
1270 1280 1290 1300 1310 1320
pF1KE2 TKTIKTSHYLTPQSNHLSLSKSNSVSLVPPGSSHTLPRRAQSLKAPSIATIKSLADCNFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TKTIKTSHYLTPQSNHLSLSKSNSVSLVPPGSSHTLPRRAQSLKAPSIATIKSLADCNFS
1250 1260 1270 1280 1290 1300
1330 1340 1350 1360 1370 1380
pF1KE2 YTSSRDAFGYATLKRLQQQRMHPSLSHSEALASPAKDVLFTDTITMKANSFESRLTPSRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YTSSRDAFGYATLKRLQQQRMHPSLSHSEALASPAKDVLFTDTITMKANSFESRLTPSRF
1310 1320 1330 1340 1350 1360
1390 1400 1410 1420 1430 1440
pF1KE2 MKALSYASLDKEDLLSPINQNTLQRSSSVRSMVSSATYGGSDDYIGLALPVDINDIFQVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKALSYASLDKEDLLSPINQNTLQRSSSVRSMVSSATYGGSDDYIGLALPVDINDIFQVK
1370 1380 1390 1400 1410 1420
1450 1460 1470 1480 1490 1500
pF1KE2 DIPYFQTKNIPPHDDRGARAFAHDAGGLPSGTGGLVKNSFHLLRQQMSLTEIMNSIHSDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DIPYFQTKNIPPHDDRGARAFAHDAGGLPSGTGGLVKNSFHLLRQQMSLTEIMNSIHSDA
1430 1440 1450 1460 1470 1480
1510 1520 1530 1540 1550 1560
pF1KE2 SLFLESTEDTGLQEHTDDNCLYCVCIEILGFQPSNQLSAICSHSDFQDIPYSDWCEQTIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLFLESTEDTGLQEHTDDNCLYCVCIEILGFQPSNQLSAICSHSDFQDIPYSDWCEQTIH
1490 1500 1510 1520 1530 1540
1570 1580 1590 1600 1610 1620
pF1KE2 NPLEVVPSKFSGISGCSDGVSQEGSASSTKSTELLLGVKTIPDDTPMCRILLRKEVLRLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPLEVVPSKFSGISGCSDGVSQEGSASSTKSTELLLGVKTIPDDTPMCRILLRKEVLRLV
1550 1560 1570 1580 1590 1600
1630 1640 1650 1660 1670 1680
pF1KE2 INLSSSVSTKCHETGLLTIKEKYPQTFDDICLYSEVSHLLSHCTFRLPCRRFIQELFQDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INLSSSVSTKCHETGLLTIKEKYPQTFDDICLYSEVSHLLSHCTFRLPCRRFIQELFQDV
1610 1620 1630 1640 1650 1660
1690 1700
pF1KE2 QFLQMHEEAEAVLATPPKQPIVDTSAES
::::::::::::::::::::::::::::
XP_016 QFLQMHEEAEAVLATPPKQPIVDTSAES
1670 1680 1690
>>XP_006714526 (OMIM: 609022) PREDICTED: rapamycin-insen (1670 aa)
initn: 9580 init1: 9580 opt: 9580 Z-score: 10057.7 bits: 1874.0 E(85289): 0
Smith-Waterman score: 10870; 97.8% identity (97.8% similar) in 1708 aa overlap (1-1708:1-1670)
10 20 30 40 50 60
pF1KE2 MAAIGRGRSLKNLRVRGRNDSGEENVPLDLTREPSDNLREILQNVARLQGVSNMRKLGHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAAIGRGRSLKNLRVRGRNDSGEENVPLDLTREPSDNLREILQNVARLQGVSNMRKLGHL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 NNFTKLLCDIGHSEEKLGFHYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NNFTKLLCDIGHSEEKLGFHYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 LKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVTNSLIAVGNDGLQER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVTNSLIAVGNDGLQER
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 DRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 RQYVRADVELERILAPYTDFHYRHSPDTAEGQLKEDREARFLASKMGIIATFRSWAGIIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RQYVRADVELERILAPYTDFHYRHSPDTAEGQLKEDREARFLASKMGIIATFRSWAGIIN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 LCKPGNSGIQSLIGVLCIPNMEIRRGLLEVLYDIFRLPLPVVTEEFIEALLSVDPGRFQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LCKPGNSGIQSLIGVLCIPNMEIRRGLLEVLYDIFRLPLPVVTEEFIEALLSVDPGRFQD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 SWRLSDGFVAAEAKTILPHRARSRPDLMDNYLALILSAFIRNGLLEGLVEVITNSDDHIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SWRLSDGFVAAEAKTILPHRARSRPDLMDNYLALILSAFIRNGLLEGLVEVITNSDDHIS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 VRATILLGELLHMANTILPHSHSHHLHCLPTLMNMAASFDIPKEKRLRASAALNCLKRFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VRATILLGELLHMANTILPHSHSHHLHCLPTLMNMAASFDIPKEKRLRASAALNCLKRFH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 EMKKRGPKPYSLHLDHIIQKAIATHQKRDQYLRVQKDIFILKDTEEALLINLRDSQVLQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EMKKRGPKPYSLHLDHIIQKAIATHQKRDQYLRVQKDIFILKDTEEALLINLRDSQVLQH
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 KENLEWNWNLIGTILKWPNVNLRNYKDEQLHRFVRRLLYFYKPSSKLYANLDLDFAKAKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KENLEWNWNLIGTILKWPNVNLRNYKDEQLHRFVRRLLYFYKPSSKLYANLDLDFAKAKQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 LTVVGCQFTEFLLESEEDGQGYLEDLVKDIVQWLNASSGMKPERSLQNNGLLTTLSQHYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LTVVGCQFTEFLLESEEDGQGYLEDLVKDIVQWLNASSGMKPERSLQNNGLLTTLSQHYF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 LFIGTLSCHPHGVKMLEKCSVFQCLLNLCSLKNQDHLLKLTVSSLDYSRDGLARVILSKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LFIGTLSCHPHGVKMLEKCSVFQCLLNLCSLKNQDHLLKLTVSSLDYSRDGLARVILSKI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 LTAATDACRLYATKHLRVLLRANVEFFNNWGIELLVTQLHDKNKTISSEALDILDEACED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LTAATDACRLYATKHLRVLLRANVEFFNNWGIELLVTQLHDKNKTISSEALDILDEACED
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 KANLHALIQMKPALSHLGDKGLLLLLRFLSIPKGFSYLNERGYVAKQLEKWHREYNSKYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KANLHALIQMKPALSHLGDKGLLLLLRFLSIPKGFSYLNERGYVAKQLEKWHREYNSKYV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 DLIEEQLNEALTTYRKPVDGDNYVRRSNQRLQRPHVYLPIHLYGQLVHHKTGCHLLEVQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DLIEEQLNEALTTYRKPVDGDNYVRRSNQRLQRPHVYLPIHLYGQLVHHKTGCHLLEVQN
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 IITELCRNVRTPDLDKWEEIKKLKASLWALGNIGSSNWGLNLLQEENVIPDILKLAKQCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IITELCRNVRTPDLDKWEEIKKLKASLWALGNIGSSNWGLNLLQEENVIPDILKLAKQCE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 VLSIRGTCVYVLGLIAKTKQGCDILKCHNWDAVRHSRKHLWPVVPDDVEQLCNELSSIPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VLSIRGTCVYVLGLIAKTKQGCDILKCHNWDAVRHSRKHLWPVVPDDVEQLCNELSSIPS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 TLSLNSESTSSRHNSESESVPSSMFILEDDRFGSSSTSTFFLDINEDTEPTFYDRSGPIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TLSLNSESTSSRHNSESESVPSSMFILEDDRFGSSSTSTFFLDINEDTEPTFYDRSGPIK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 DKNSFPFFASSKLVKNRILNSLTLPNKKHRSSSDPKGGKLSSESKTSNRRIRTLTEPSVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DKNSFPFFASSKLVKNRILNSLTLPNKKHRSSSDPKGGKLSSESKTSNRRIRTLTEPSVD
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 FNHSDDFTPISTVQKTLQLETSFMGNKHIEDTGSTPSIGENDLKFTKNFGTENHRENTSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FNHSDDFTPISTVQKTLQLETSFMGNKHIEDTGSTPSIGENDLKFTKNFGTENHRENTSR
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 ERLVVESSTSSHMKIRSQSFNTDTTTSGISSMSSSPSRETVGVDATTMDTDCGSMSTVVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ERLVVESSTSSHMKIRSQSFNTDTTTSGISSMSSSPSRETVGVDATTMDTDCGSMSTVVS
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 TKTIKTSHYLTPQSNHLSLSKSNSVSLVPPGSSHTLPRRAQSLKAPSIATIKSLADCNFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TKTIKTSHYLTPQSNHLSLSKSNSVSLVPPGSSHTLPRRAQSLKAPSIATIKSLADCNFS
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 YTSSRDAFGYATLKRLQQQRMHPSLSHSEALASPAKDVLFTDTITMKANSFESRLTPSRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YTSSRDAFGYATLKRLQQQRMHPSLSHSEALASPAKDVLFTDTITMKANSFESRLTPSRF
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 MKALSYASLDKEDLLSPINQNTLQRSSSVRSMVSSATYGGSDDYIGLALPVDINDIFQVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MKALSYASLDKEDLLSPINQNTLQRSSSVRSMVSSATYGGSDDYIGLALPVDINDIFQVK
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE2 DIPYFQTKNIPPHDDRGARAFAHDAGGLPSGTGGLVKNSFHLLRQQMSLTEIMNSIHSDA
::::::::::::::::::::::::::
XP_006 DIPYFQTKNIPPHDDRGARAFAHDAG----------------------------------
1450 1460
1510 1520 1530 1540 1550 1560
pF1KE2 SLFLESTEDTGLQEHTDDNCLYCVCIEILGFQPSNQLSAICSHSDFQDIPYSDWCEQTIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ----ESTEDTGLQEHTDDNCLYCVCIEILGFQPSNQLSAICSHSDFQDIPYSDWCEQTIH
1470 1480 1490 1500 1510 1520
1570 1580 1590 1600 1610 1620
pF1KE2 NPLEVVPSKFSGISGCSDGVSQEGSASSTKSTELLLGVKTIPDDTPMCRILLRKEVLRLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NPLEVVPSKFSGISGCSDGVSQEGSASSTKSTELLLGVKTIPDDTPMCRILLRKEVLRLV
1530 1540 1550 1560 1570 1580
1630 1640 1650 1660 1670 1680
pF1KE2 INLSSSVSTKCHETGLLTIKEKYPQTFDDICLYSEVSHLLSHCTFRLPCRRFIQELFQDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 INLSSSVSTKCHETGLLTIKEKYPQTFDDICLYSEVSHLLSHCTFRLPCRRFIQELFQDV
1590 1600 1610 1620 1630 1640
1690 1700
pF1KE2 QFLQMHEEAEAVLATPPKQPIVDTSAES
::::::::::::::::::::::::::::
XP_006 QFLQMHEEAEAVLATPPKQPIVDTSAES
1650 1660 1670
>>XP_016864804 (OMIM: 609022) PREDICTED: rapamycin-insen (1423 aa)
initn: 9378 init1: 9378 opt: 9378 Z-score: 9846.6 bits: 1834.7 E(85289): 0
Smith-Waterman score: 9378; 100.0% identity (100.0% similar) in 1423 aa overlap (286-1708:1-1423)
260 270 280 290 300 310
pF1KE2 PYTDFHYRHSPDTAEGQLKEDREARFLASKMGIIATFRSWAGIINLCKPGNSGIQSLIGV
::::::::::::::::::::::::::::::
XP_016 MGIIATFRSWAGIINLCKPGNSGIQSLIGV
10 20 30
320 330 340 350 360 370
pF1KE2 LCIPNMEIRRGLLEVLYDIFRLPLPVVTEEFIEALLSVDPGRFQDSWRLSDGFVAAEAKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LCIPNMEIRRGLLEVLYDIFRLPLPVVTEEFIEALLSVDPGRFQDSWRLSDGFVAAEAKT
40 50 60 70 80 90
380 390 400 410 420 430
pF1KE2 ILPHRARSRPDLMDNYLALILSAFIRNGLLEGLVEVITNSDDHISVRATILLGELLHMAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILPHRARSRPDLMDNYLALILSAFIRNGLLEGLVEVITNSDDHISVRATILLGELLHMAN
100 110 120 130 140 150
440 450 460 470 480 490
pF1KE2 TILPHSHSHHLHCLPTLMNMAASFDIPKEKRLRASAALNCLKRFHEMKKRGPKPYSLHLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TILPHSHSHHLHCLPTLMNMAASFDIPKEKRLRASAALNCLKRFHEMKKRGPKPYSLHLD
160 170 180 190 200 210
500 510 520 530 540 550
pF1KE2 HIIQKAIATHQKRDQYLRVQKDIFILKDTEEALLINLRDSQVLQHKENLEWNWNLIGTIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HIIQKAIATHQKRDQYLRVQKDIFILKDTEEALLINLRDSQVLQHKENLEWNWNLIGTIL
220 230 240 250 260 270
560 570 580 590 600 610
pF1KE2 KWPNVNLRNYKDEQLHRFVRRLLYFYKPSSKLYANLDLDFAKAKQLTVVGCQFTEFLLES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KWPNVNLRNYKDEQLHRFVRRLLYFYKPSSKLYANLDLDFAKAKQLTVVGCQFTEFLLES
280 290 300 310 320 330
620 630 640 650 660 670
pF1KE2 EEDGQGYLEDLVKDIVQWLNASSGMKPERSLQNNGLLTTLSQHYFLFIGTLSCHPHGVKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEDGQGYLEDLVKDIVQWLNASSGMKPERSLQNNGLLTTLSQHYFLFIGTLSCHPHGVKM
340 350 360 370 380 390
680 690 700 710 720 730
pF1KE2 LEKCSVFQCLLNLCSLKNQDHLLKLTVSSLDYSRDGLARVILSKILTAATDACRLYATKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEKCSVFQCLLNLCSLKNQDHLLKLTVSSLDYSRDGLARVILSKILTAATDACRLYATKH
400 410 420 430 440 450
740 750 760 770 780 790
pF1KE2 LRVLLRANVEFFNNWGIELLVTQLHDKNKTISSEALDILDEACEDKANLHALIQMKPALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRVLLRANVEFFNNWGIELLVTQLHDKNKTISSEALDILDEACEDKANLHALIQMKPALS
460 470 480 490 500 510
800 810 820 830 840 850
pF1KE2 HLGDKGLLLLLRFLSIPKGFSYLNERGYVAKQLEKWHREYNSKYVDLIEEQLNEALTTYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLGDKGLLLLLRFLSIPKGFSYLNERGYVAKQLEKWHREYNSKYVDLIEEQLNEALTTYR
520 530 540 550 560 570
860 870 880 890 900 910
pF1KE2 KPVDGDNYVRRSNQRLQRPHVYLPIHLYGQLVHHKTGCHLLEVQNIITELCRNVRTPDLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPVDGDNYVRRSNQRLQRPHVYLPIHLYGQLVHHKTGCHLLEVQNIITELCRNVRTPDLD
580 590 600 610 620 630
920 930 940 950 960 970
pF1KE2 KWEEIKKLKASLWALGNIGSSNWGLNLLQEENVIPDILKLAKQCEVLSIRGTCVYVLGLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KWEEIKKLKASLWALGNIGSSNWGLNLLQEENVIPDILKLAKQCEVLSIRGTCVYVLGLI
640 650 660 670 680 690
980 990 1000 1010 1020 1030
pF1KE2 AKTKQGCDILKCHNWDAVRHSRKHLWPVVPDDVEQLCNELSSIPSTLSLNSESTSSRHNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKTKQGCDILKCHNWDAVRHSRKHLWPVVPDDVEQLCNELSSIPSTLSLNSESTSSRHNS
700 710 720 730 740 750
1040 1050 1060 1070 1080 1090
pF1KE2 ESESVPSSMFILEDDRFGSSSTSTFFLDINEDTEPTFYDRSGPIKDKNSFPFFASSKLVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESESVPSSMFILEDDRFGSSSTSTFFLDINEDTEPTFYDRSGPIKDKNSFPFFASSKLVK
760 770 780 790 800 810
1100 1110 1120 1130 1140 1150
pF1KE2 NRILNSLTLPNKKHRSSSDPKGGKLSSESKTSNRRIRTLTEPSVDFNHSDDFTPISTVQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NRILNSLTLPNKKHRSSSDPKGGKLSSESKTSNRRIRTLTEPSVDFNHSDDFTPISTVQK
820 830 840 850 860 870
1160 1170 1180 1190 1200 1210
pF1KE2 TLQLETSFMGNKHIEDTGSTPSIGENDLKFTKNFGTENHRENTSRERLVVESSTSSHMKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLQLETSFMGNKHIEDTGSTPSIGENDLKFTKNFGTENHRENTSRERLVVESSTSSHMKI
880 890 900 910 920 930
1220 1230 1240 1250 1260 1270
pF1KE2 RSQSFNTDTTTSGISSMSSSPSRETVGVDATTMDTDCGSMSTVVSTKTIKTSHYLTPQSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSQSFNTDTTTSGISSMSSSPSRETVGVDATTMDTDCGSMSTVVSTKTIKTSHYLTPQSN
940 950 960 970 980 990
1280 1290 1300 1310 1320 1330
pF1KE2 HLSLSKSNSVSLVPPGSSHTLPRRAQSLKAPSIATIKSLADCNFSYTSSRDAFGYATLKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLSLSKSNSVSLVPPGSSHTLPRRAQSLKAPSIATIKSLADCNFSYTSSRDAFGYATLKR
1000 1010 1020 1030 1040 1050
1340 1350 1360 1370 1380 1390
pF1KE2 LQQQRMHPSLSHSEALASPAKDVLFTDTITMKANSFESRLTPSRFMKALSYASLDKEDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQQQRMHPSLSHSEALASPAKDVLFTDTITMKANSFESRLTPSRFMKALSYASLDKEDLL
1060 1070 1080 1090 1100 1110
1400 1410 1420 1430 1440 1450
pF1KE2 SPINQNTLQRSSSVRSMVSSATYGGSDDYIGLALPVDINDIFQVKDIPYFQTKNIPPHDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPINQNTLQRSSSVRSMVSSATYGGSDDYIGLALPVDINDIFQVKDIPYFQTKNIPPHDD
1120 1130 1140 1150 1160 1170
1460 1470 1480 1490 1500 1510
pF1KE2 RGARAFAHDAGGLPSGTGGLVKNSFHLLRQQMSLTEIMNSIHSDASLFLESTEDTGLQEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGARAFAHDAGGLPSGTGGLVKNSFHLLRQQMSLTEIMNSIHSDASLFLESTEDTGLQEH
1180 1190 1200 1210 1220 1230
1520 1530 1540 1550 1560 1570
pF1KE2 TDDNCLYCVCIEILGFQPSNQLSAICSHSDFQDIPYSDWCEQTIHNPLEVVPSKFSGISG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDDNCLYCVCIEILGFQPSNQLSAICSHSDFQDIPYSDWCEQTIHNPLEVVPSKFSGISG
1240 1250 1260 1270 1280 1290
1580 1590 1600 1610 1620 1630
pF1KE2 CSDGVSQEGSASSTKSTELLLGVKTIPDDTPMCRILLRKEVLRLVINLSSSVSTKCHETG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CSDGVSQEGSASSTKSTELLLGVKTIPDDTPMCRILLRKEVLRLVINLSSSVSTKCHETG
1300 1310 1320 1330 1340 1350
1640 1650 1660 1670 1680 1690
pF1KE2 LLTIKEKYPQTFDDICLYSEVSHLLSHCTFRLPCRRFIQELFQDVQFLQMHEEAEAVLAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLTIKEKYPQTFDDICLYSEVSHLLSHCTFRLPCRRFIQELFQDVQFLQMHEEAEAVLAT
1360 1370 1380 1390 1400 1410
1700
pF1KE2 PPKQPIVDTSAES
:::::::::::::
XP_016 PPKQPIVDTSAES
1420
>>XP_011512307 (OMIM: 609022) PREDICTED: rapamycin-insen (1694 aa)
initn: 10370 init1: 9004 opt: 9004 Z-score: 9452.5 bits: 1762.1 E(85289): 0
Smith-Waterman score: 10812; 96.4% identity (96.4% similar) in 1732 aa overlap (1-1708:1-1694)
10 20 30 40 50 60
pF1KE2 MAAIGRGRSLKNLRVRGRNDSGEENVPLDLTREPSDNLREILQNVARLQGVSNMRKLGHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAAIGRGRSLKNLRVRGRNDSGEENVPLDLTREPSDNLREILQNVARLQGVSNMRKLGHL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 NNFTKLLCDIGHSEEKLGFHYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NNFTKLLCDIGHSEEKLGFHYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 LKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVTNSLIAVGNDGLQER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVTNSLIAVGNDGLQER
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 DRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 RQYVRADVELERILAPYTDFHYRHSPDTAEGQLKEDREARFLASKMGIIATFRSWAGIIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQYVRADVELERILAPYTDFHYRHSPDTAEGQLKEDREARFLASKMGIIATFRSWAGIIN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 LCKPGNSGIQSLIGVLCIPNMEIRRGLLEVLYDIFRLPLPVVTEEFIEALLSVDPGRFQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LCKPGNSGIQSLIGVLCIPNMEIRRGLLEVLYDIFRLPLPVVTEEFIEALLSVDPGRFQD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 SWRLSDGFVAAEAKTILPHRARSRPDLMDNYLALILSAFIRNGLLEGLVEVITNSDDHIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SWRLSDGFVAAEAKTILPHRARSRPDLMDNYLALILSAFIRNGLLEGLVEVITNSDDHIS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 VRATILLGELLHMANTILPHSHSHHLHCLPTLMNMAASFDIPKEKRLRASAALNCLKRFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRATILLGELLHMANTILPHSHSHHLHCLPTLMNMAASFDIPKEKRLRASAALNCLKRFH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 EMKKRGPKPYSLHLDHIIQKAIATHQKRDQYLRVQKDIFILKDTEEALLINLRDSQVLQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EMKKRGPKPYSLHLDHIIQKAIATHQKRDQYLRVQKDIFILKDTEEALLINLRDSQVLQH
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 KENLEWNWNLIGTILKWPNVNLRNYKDEQLHRFVRRLLYFYKPSSKLYANLDLDFAKAKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KENLEWNWNLIGTILKWPNVNLRNYKDEQLHRFVRRLLYFYKPSSKLYANLDLDFAKAKQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 LTVVGCQFTEFLLESEEDGQGYLEDLVKDIVQWLNASSGMKPERSLQNNGLLTTLSQHYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTVVGCQFTEFLLESEEDGQGYLEDLVKDIVQWLNASSGMKPERSLQNNGLLTTLSQHYF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 LFIGTLSCHPHGVKMLEKCSVFQCLLNLCSLKNQDHLLKLTVSSLDYSRDGLARVILSKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFIGTLSCHPHGVKMLEKCSVFQCLLNLCSLKNQDHLLKLTVSSLDYSRDGLARVILSKI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 LTAATDACRLYATKHLRVLLRANVEFFNNWGIELLVTQLHDKNKTISSEALDILDEACED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTAATDACRLYATKHLRVLLRANVEFFNNWGIELLVTQLHDKNKTISSEALDILDEACED
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 KANLHALIQMKPALSHLGDKGLLLLLRFLSIPKGFSYLNERGYVAKQLEKWHREYNSKYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KANLHALIQMKPALSHLGDKGLLLLLRFLSIPKGFSYLNERGYVAKQLEKWHREYNSKYV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 DLIEEQLNEALTTYRKPVDGDNYVRRSNQRLQRPHVYLPIHLYGQLVHHKTGCHLLEVQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLIEEQLNEALTTYRKPVDGDNYVRRSNQRLQRPHVYLPIHLYGQLVHHKTGCHLLEVQN
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 IITELCRNVRTPDLDKWEEIKKLKASLWALGNIGSSNWGLNLLQEENVIPDILKLAKQCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IITELCRNVRTPDLDKWEEIKKLKASLWALGNIGSSNWGLNLLQEENVIPDILKLAKQCE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 VLSIRGTCVYVLGLIAKTKQGCDILKCHNWDAVRHSRKHLWPVVPDDVEQLCNELSSIPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLSIRGTCVYVLGLIAKTKQGCDILKCHNWDAVRHSRKHLWPVVPDDVEQLCNELSSIPS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 TLSLNSESTSSRHNSESESVPSSMFILEDDRFGSSSTSTFFLDINEDTEPTFYDRSGPIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLSLNSESTSSRHNSESESVPSSMFILEDDRFGSSSTSTFFLDINEDTEPTFYDRSGPIK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 DKNSFPFFASSKLVKNRILNSLTLPNKKHRSSSDPKGGKLSSESKTSNRRIRTLTEPSVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKNSFPFFASSKLVKNRILNSLTLPNKKHRSSSDPKGGKLSSESKTSNRRIRTLTEPSVD
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 FNHSDDFTPISTVQKTLQLETSFMGNKHIEDTGSTPSIGENDLKFTKNFGTENHRENTSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FNHSDDFTPISTVQKTLQLETSFMGNKHIEDTGSTPSIGENDLKFTKNFGTENHRENTSR
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 ERLVVESSTSSHMKIRSQSFNTDTTTSGISSMSSSPSRETVGVDATTMDTDCGSMSTVVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERLVVESSTSSHMKIRSQSFNTDTTTSGISSMSSSPSRETVGVDATTMDTDCGSMSTVVS
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 TKTIKTSHYLTPQSNHLSLSKSNSVSLVPPGSSHTLPRRAQSLKAPSIATIKSLADCNFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKTIKTSHYLTPQSNHLSLSKSNSVSLVPPGSSHTLPRRAQSLKAPSIATIKSLADCNFS
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370
pF1KE2 YTSSRDAFGYATLKRLQQQRMHPSLSHSEALASPAKDVLFTDTITMKANSFESRLTPSR-
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YTSSRDAFGYATLKRLQQQRMHPSLSHSEALASPAKDVLFTDTITMKANSFESRLTPSRI
1330 1340 1350 1360 1370 1380
1380 1390 1400 1410
pF1KE2 -----------------------FMKALSYASLDKEDLLSPINQNTLQRSSSVRSMVSSA
:::::::::::::::::::::::::::::::::::::
XP_011 DFKKKHVGGIRSLRPTITNNLFRFMKALSYASLDKEDLLSPINQNTLQRSSSVRSMVSSA
1390 1400 1410 1420 1430 1440
1420 1430 1440 1450 1460 1470
pF1KE2 TYGGSDDYIGLALPVDINDIFQVKDIPYFQTKNIPPHDDRGARAFAHDAGGLPSGTGGLV
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TYGGSDDYIGLALPVDINDIFQVKDIPYFQTKNIPPHDDRGARAFAHDAG----------
1450 1460 1470 1480 1490
1480 1490 1500 1510 1520 1530
pF1KE2 KNSFHLLRQQMSLTEIMNSIHSDASLFLESTEDTGLQEHTDDNCLYCVCIEILGFQPSNQ
::::::::::::::::::::::::::::::::
XP_011 ----------------------------ESTEDTGLQEHTDDNCLYCVCIEILGFQPSNQ
1500 1510 1520
1540 1550 1560 1570 1580 1590
pF1KE2 LSAICSHSDFQDIPYSDWCEQTIHNPLEVVPSKFSGISGCSDGVSQEGSASSTKSTELLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSAICSHSDFQDIPYSDWCEQTIHNPLEVVPSKFSGISGCSDGVSQEGSASSTKSTELLL
1530 1540 1550 1560 1570 1580
1600 1610 1620 1630 1640 1650
pF1KE2 GVKTIPDDTPMCRILLRKEVLRLVINLSSSVSTKCHETGLLTIKEKYPQTFDDICLYSEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVKTIPDDTPMCRILLRKEVLRLVINLSSSVSTKCHETGLLTIKEKYPQTFDDICLYSEV
1590 1600 1610 1620 1630 1640
1660 1670 1680 1690 1700
pF1KE2 SHLLSHCTFRLPCRRFIQELFQDVQFLQMHEEAEAVLATPPKQPIVDTSAES
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SHLLSHCTFRLPCRRFIQELFQDVQFLQMHEEAEAVLATPPKQPIVDTSAES
1650 1660 1670 1680 1690
>>NP_001272368 (OMIM: 609022) rapamycin-insensitive comp (1732 aa)
initn: 9004 init1: 9004 opt: 9004 Z-score: 9452.3 bits: 1762.1 E(85289): 0
Smith-Waterman score: 11140; 98.6% identity (98.6% similar) in 1732 aa overlap (1-1708:1-1732)
10 20 30 40 50 60
pF1KE2 MAAIGRGRSLKNLRVRGRNDSGEENVPLDLTREPSDNLREILQNVARLQGVSNMRKLGHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAIGRGRSLKNLRVRGRNDSGEENVPLDLTREPSDNLREILQNVARLQGVSNMRKLGHL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 NNFTKLLCDIGHSEEKLGFHYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNFTKLLCDIGHSEEKLGFHYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 LKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVTNSLIAVGNDGLQER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVTNSLIAVGNDGLQER
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 DRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 RQYVRADVELERILAPYTDFHYRHSPDTAEGQLKEDREARFLASKMGIIATFRSWAGIIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQYVRADVELERILAPYTDFHYRHSPDTAEGQLKEDREARFLASKMGIIATFRSWAGIIN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 LCKPGNSGIQSLIGVLCIPNMEIRRGLLEVLYDIFRLPLPVVTEEFIEALLSVDPGRFQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LCKPGNSGIQSLIGVLCIPNMEIRRGLLEVLYDIFRLPLPVVTEEFIEALLSVDPGRFQD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 SWRLSDGFVAAEAKTILPHRARSRPDLMDNYLALILSAFIRNGLLEGLVEVITNSDDHIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SWRLSDGFVAAEAKTILPHRARSRPDLMDNYLALILSAFIRNGLLEGLVEVITNSDDHIS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 VRATILLGELLHMANTILPHSHSHHLHCLPTLMNMAASFDIPKEKRLRASAALNCLKRFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRATILLGELLHMANTILPHSHSHHLHCLPTLMNMAASFDIPKEKRLRASAALNCLKRFH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 EMKKRGPKPYSLHLDHIIQKAIATHQKRDQYLRVQKDIFILKDTEEALLINLRDSQVLQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EMKKRGPKPYSLHLDHIIQKAIATHQKRDQYLRVQKDIFILKDTEEALLINLRDSQVLQH
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 KENLEWNWNLIGTILKWPNVNLRNYKDEQLHRFVRRLLYFYKPSSKLYANLDLDFAKAKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KENLEWNWNLIGTILKWPNVNLRNYKDEQLHRFVRRLLYFYKPSSKLYANLDLDFAKAKQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 LTVVGCQFTEFLLESEEDGQGYLEDLVKDIVQWLNASSGMKPERSLQNNGLLTTLSQHYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTVVGCQFTEFLLESEEDGQGYLEDLVKDIVQWLNASSGMKPERSLQNNGLLTTLSQHYF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 LFIGTLSCHPHGVKMLEKCSVFQCLLNLCSLKNQDHLLKLTVSSLDYSRDGLARVILSKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFIGTLSCHPHGVKMLEKCSVFQCLLNLCSLKNQDHLLKLTVSSLDYSRDGLARVILSKI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 LTAATDACRLYATKHLRVLLRANVEFFNNWGIELLVTQLHDKNKTISSEALDILDEACED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTAATDACRLYATKHLRVLLRANVEFFNNWGIELLVTQLHDKNKTISSEALDILDEACED
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 KANLHALIQMKPALSHLGDKGLLLLLRFLSIPKGFSYLNERGYVAKQLEKWHREYNSKYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KANLHALIQMKPALSHLGDKGLLLLLRFLSIPKGFSYLNERGYVAKQLEKWHREYNSKYV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 DLIEEQLNEALTTYRKPVDGDNYVRRSNQRLQRPHVYLPIHLYGQLVHHKTGCHLLEVQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLIEEQLNEALTTYRKPVDGDNYVRRSNQRLQRPHVYLPIHLYGQLVHHKTGCHLLEVQN
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 IITELCRNVRTPDLDKWEEIKKLKASLWALGNIGSSNWGLNLLQEENVIPDILKLAKQCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IITELCRNVRTPDLDKWEEIKKLKASLWALGNIGSSNWGLNLLQEENVIPDILKLAKQCE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 VLSIRGTCVYVLGLIAKTKQGCDILKCHNWDAVRHSRKHLWPVVPDDVEQLCNELSSIPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLSIRGTCVYVLGLIAKTKQGCDILKCHNWDAVRHSRKHLWPVVPDDVEQLCNELSSIPS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 TLSLNSESTSSRHNSESESVPSSMFILEDDRFGSSSTSTFFLDINEDTEPTFYDRSGPIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLSLNSESTSSRHNSESESVPSSMFILEDDRFGSSSTSTFFLDINEDTEPTFYDRSGPIK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 DKNSFPFFASSKLVKNRILNSLTLPNKKHRSSSDPKGGKLSSESKTSNRRIRTLTEPSVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKNSFPFFASSKLVKNRILNSLTLPNKKHRSSSDPKGGKLSSESKTSNRRIRTLTEPSVD
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 FNHSDDFTPISTVQKTLQLETSFMGNKHIEDTGSTPSIGENDLKFTKNFGTENHRENTSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNHSDDFTPISTVQKTLQLETSFMGNKHIEDTGSTPSIGENDLKFTKNFGTENHRENTSR
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 ERLVVESSTSSHMKIRSQSFNTDTTTSGISSMSSSPSRETVGVDATTMDTDCGSMSTVVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERLVVESSTSSHMKIRSQSFNTDTTTSGISSMSSSPSRETVGVDATTMDTDCGSMSTVVS
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 TKTIKTSHYLTPQSNHLSLSKSNSVSLVPPGSSHTLPRRAQSLKAPSIATIKSLADCNFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TKTIKTSHYLTPQSNHLSLSKSNSVSLVPPGSSHTLPRRAQSLKAPSIATIKSLADCNFS
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370
pF1KE2 YTSSRDAFGYATLKRLQQQRMHPSLSHSEALASPAKDVLFTDTITMKANSFESRLTPSR-
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YTSSRDAFGYATLKRLQQQRMHPSLSHSEALASPAKDVLFTDTITMKANSFESRLTPSRI
1330 1340 1350 1360 1370 1380
1380 1390 1400 1410
pF1KE2 -----------------------FMKALSYASLDKEDLLSPINQNTLQRSSSVRSMVSSA
:::::::::::::::::::::::::::::::::::::
NP_001 DFKKKHVGGIRSLRPTITNNLFRFMKALSYASLDKEDLLSPINQNTLQRSSSVRSMVSSA
1390 1400 1410 1420 1430 1440
1420 1430 1440 1450 1460 1470
pF1KE2 TYGGSDDYIGLALPVDINDIFQVKDIPYFQTKNIPPHDDRGARAFAHDAGGLPSGTGGLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TYGGSDDYIGLALPVDINDIFQVKDIPYFQTKNIPPHDDRGARAFAHDAGGLPSGTGGLV
1450 1460 1470 1480 1490 1500
1480 1490 1500 1510 1520 1530
pF1KE2 KNSFHLLRQQMSLTEIMNSIHSDASLFLESTEDTGLQEHTDDNCLYCVCIEILGFQPSNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KNSFHLLRQQMSLTEIMNSIHSDASLFLESTEDTGLQEHTDDNCLYCVCIEILGFQPSNQ
1510 1520 1530 1540 1550 1560
1540 1550 1560 1570 1580 1590
pF1KE2 LSAICSHSDFQDIPYSDWCEQTIHNPLEVVPSKFSGISGCSDGVSQEGSASSTKSTELLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSAICSHSDFQDIPYSDWCEQTIHNPLEVVPSKFSGISGCSDGVSQEGSASSTKSTELLL
1570 1580 1590 1600 1610 1620
1600 1610 1620 1630 1640 1650
pF1KE2 GVKTIPDDTPMCRILLRKEVLRLVINLSSSVSTKCHETGLLTIKEKYPQTFDDICLYSEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVKTIPDDTPMCRILLRKEVLRLVINLSSSVSTKCHETGLLTIKEKYPQTFDDICLYSEV
1630 1640 1650 1660 1670 1680
1660 1670 1680 1690 1700
pF1KE2 SHLLSHCTFRLPCRRFIQELFQDVQFLQMHEEAEAVLATPPKQPIVDTSAES
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SHLLSHCTFRLPCRRFIQELFQDVQFLQMHEEAEAVLATPPKQPIVDTSAES
1690 1700 1710 1720 1730
>>XP_016864800 (OMIM: 609022) PREDICTED: rapamycin-insen (1716 aa)
initn: 8805 init1: 8805 opt: 8805 Z-score: 9243.3 bits: 1723.4 E(85289): 0
Smith-Waterman score: 10991; 97.7% identity (97.7% similar) in 1732 aa overlap (1-1708:1-1716)
10 20 30 40 50 60
pF1KE2 MAAIGRGRSLKNLRVRGRNDSGEENVPLDLTREPSDNLREILQNVARLQGVSNMRKLGHL
:::::::::::::::: ::::::::::::::::::::::::::::
XP_016 MAAIGRGRSLKNLRVR----------------EPSDNLREILQNVARLQGVSNMRKLGHL
10 20 30 40
70 80 90 100 110 120
pF1KE2 NNFTKLLCDIGHSEEKLGFHYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNFTKLLCDIGHSEEKLGFHYEDIIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKV
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE2 LKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVTNSLIAVGNDGLQER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSVTNSLIAVGNDGLQER
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE2 DRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKT
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE2 RQYVRADVELERILAPYTDFHYRHSPDTAEGQLKEDREARFLASKMGIIATFRSWAGIIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQYVRADVELERILAPYTDFHYRHSPDTAEGQLKEDREARFLASKMGIIATFRSWAGIIN
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE2 LCKPGNSGIQSLIGVLCIPNMEIRRGLLEVLYDIFRLPLPVVTEEFIEALLSVDPGRFQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LCKPGNSGIQSLIGVLCIPNMEIRRGLLEVLYDIFRLPLPVVTEEFIEALLSVDPGRFQD
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE2 SWRLSDGFVAAEAKTILPHRARSRPDLMDNYLALILSAFIRNGLLEGLVEVITNSDDHIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SWRLSDGFVAAEAKTILPHRARSRPDLMDNYLALILSAFIRNGLLEGLVEVITNSDDHIS
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE2 VRATILLGELLHMANTILPHSHSHHLHCLPTLMNMAASFDIPKEKRLRASAALNCLKRFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRATILLGELLHMANTILPHSHSHHLHCLPTLMNMAASFDIPKEKRLRASAALNCLKRFH
410 420 430 440 450 460
490 500 510 520 530 540
pF1KE2 EMKKRGPKPYSLHLDHIIQKAIATHQKRDQYLRVQKDIFILKDTEEALLINLRDSQVLQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EMKKRGPKPYSLHLDHIIQKAIATHQKRDQYLRVQKDIFILKDTEEALLINLRDSQVLQH
470 480 490 500 510 520
550 560 570 580 590 600
pF1KE2 KENLEWNWNLIGTILKWPNVNLRNYKDEQLHRFVRRLLYFYKPSSKLYANLDLDFAKAKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KENLEWNWNLIGTILKWPNVNLRNYKDEQLHRFVRRLLYFYKPSSKLYANLDLDFAKAKQ
530 540 550 560 570 580
610 620 630 640 650 660
pF1KE2 LTVVGCQFTEFLLESEEDGQGYLEDLVKDIVQWLNASSGMKPERSLQNNGLLTTLSQHYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTVVGCQFTEFLLESEEDGQGYLEDLVKDIVQWLNASSGMKPERSLQNNGLLTTLSQHYF
590 600 610 620 630 640
670 680 690 700 710 720
pF1KE2 LFIGTLSCHPHGVKMLEKCSVFQCLLNLCSLKNQDHLLKLTVSSLDYSRDGLARVILSKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFIGTLSCHPHGVKMLEKCSVFQCLLNLCSLKNQDHLLKLTVSSLDYSRDGLARVILSKI
650 660 670 680 690 700
730 740 750 760 770 780
pF1KE2 LTAATDACRLYATKHLRVLLRANVEFFNNWGIELLVTQLHDKNKTISSEALDILDEACED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTAATDACRLYATKHLRVLLRANVEFFNNWGIELLVTQLHDKNKTISSEALDILDEACED
710 720 730 740 750 760
790 800 810 820 830 840
pF1KE2 KANLHALIQMKPALSHLGDKGLLLLLRFLSIPKGFSYLNERGYVAKQLEKWHREYNSKYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KANLHALIQMKPALSHLGDKGLLLLLRFLSIPKGFSYLNERGYVAKQLEKWHREYNSKYV
770 780 790 800 810 820
850 860 870 880 890 900
pF1KE2 DLIEEQLNEALTTYRKPVDGDNYVRRSNQRLQRPHVYLPIHLYGQLVHHKTGCHLLEVQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLIEEQLNEALTTYRKPVDGDNYVRRSNQRLQRPHVYLPIHLYGQLVHHKTGCHLLEVQN
830 840 850 860 870 880
910 920 930 940 950 960
pF1KE2 IITELCRNVRTPDLDKWEEIKKLKASLWALGNIGSSNWGLNLLQEENVIPDILKLAKQCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IITELCRNVRTPDLDKWEEIKKLKASLWALGNIGSSNWGLNLLQEENVIPDILKLAKQCE
890 900 910 920 930 940
970 980 990 1000 1010 1020
pF1KE2 VLSIRGTCVYVLGLIAKTKQGCDILKCHNWDAVRHSRKHLWPVVPDDVEQLCNELSSIPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLSIRGTCVYVLGLIAKTKQGCDILKCHNWDAVRHSRKHLWPVVPDDVEQLCNELSSIPS
950 960 970 980 990 1000
1030 1040 1050 1060 1070 1080
pF1KE2 TLSLNSESTSSRHNSESESVPSSMFILEDDRFGSSSTSTFFLDINEDTEPTFYDRSGPIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLSLNSESTSSRHNSESESVPSSMFILEDDRFGSSSTSTFFLDINEDTEPTFYDRSGPIK
1010 1020 1030 1040 1050 1060
1090 1100 1110 1120 1130 1140
pF1KE2 DKNSFPFFASSKLVKNRILNSLTLPNKKHRSSSDPKGGKLSSESKTSNRRIRTLTEPSVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKNSFPFFASSKLVKNRILNSLTLPNKKHRSSSDPKGGKLSSESKTSNRRIRTLTEPSVD
1070 1080 1090 1100 1110 1120
1150 1160 1170 1180 1190 1200
pF1KE2 FNHSDDFTPISTVQKTLQLETSFMGNKHIEDTGSTPSIGENDLKFTKNFGTENHRENTSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FNHSDDFTPISTVQKTLQLETSFMGNKHIEDTGSTPSIGENDLKFTKNFGTENHRENTSR
1130 1140 1150 1160 1170 1180
1210 1220 1230 1240 1250 1260
pF1KE2 ERLVVESSTSSHMKIRSQSFNTDTTTSGISSMSSSPSRETVGVDATTMDTDCGSMSTVVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERLVVESSTSSHMKIRSQSFNTDTTTSGISSMSSSPSRETVGVDATTMDTDCGSMSTVVS
1190 1200 1210 1220 1230 1240
1270 1280 1290 1300 1310 1320
pF1KE2 TKTIKTSHYLTPQSNHLSLSKSNSVSLVPPGSSHTLPRRAQSLKAPSIATIKSLADCNFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TKTIKTSHYLTPQSNHLSLSKSNSVSLVPPGSSHTLPRRAQSLKAPSIATIKSLADCNFS
1250 1260 1270 1280 1290 1300
1330 1340 1350 1360 1370
pF1KE2 YTSSRDAFGYATLKRLQQQRMHPSLSHSEALASPAKDVLFTDTITMKANSFESRLTPSR-
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YTSSRDAFGYATLKRLQQQRMHPSLSHSEALASPAKDVLFTDTITMKANSFESRLTPSRI
1310 1320 1330 1340 1350 1360
1380 1390 1400 1410
pF1KE2 -----------------------FMKALSYASLDKEDLLSPINQNTLQRSSSVRSMVSSA
:::::::::::::::::::::::::::::::::::::
XP_016 DFKKKHVGGIRSLRPTITNNLFRFMKALSYASLDKEDLLSPINQNTLQRSSSVRSMVSSA
1370 1380 1390 1400 1410 1420
1420 1430 1440 1450 1460 1470
pF1KE2 TYGGSDDYIGLALPVDINDIFQVKDIPYFQTKNIPPHDDRGARAFAHDAGGLPSGTGGLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TYGGSDDYIGLALPVDINDIFQVKDIPYFQTKNIPPHDDRGARAFAHDAGGLPSGTGGLV
1430 1440 1450 1460 1470 1480
1480 1490 1500 1510 1520 1530
pF1KE2 KNSFHLLRQQMSLTEIMNSIHSDASLFLESTEDTGLQEHTDDNCLYCVCIEILGFQPSNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNSFHLLRQQMSLTEIMNSIHSDASLFLESTEDTGLQEHTDDNCLYCVCIEILGFQPSNQ
1490 1500 1510 1520 1530 1540
1540 1550 1560 1570 1580 1590
pF1KE2 LSAICSHSDFQDIPYSDWCEQTIHNPLEVVPSKFSGISGCSDGVSQEGSASSTKSTELLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSAICSHSDFQDIPYSDWCEQTIHNPLEVVPSKFSGISGCSDGVSQEGSASSTKSTELLL
1550 1560 1570 1580 1590 1600
1600 1610 1620 1630 1640 1650
pF1KE2 GVKTIPDDTPMCRILLRKEVLRLVINLSSSVSTKCHETGLLTIKEKYPQTFDDICLYSEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVKTIPDDTPMCRILLRKEVLRLVINLSSSVSTKCHETGLLTIKEKYPQTFDDICLYSEV
1610 1620 1630 1640 1650 1660
1660 1670 1680 1690 1700
pF1KE2 SHLLSHCTFRLPCRRFIQELFQDVQFLQMHEEAEAVLATPPKQPIVDTSAES
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHLLSHCTFRLPCRRFIQELFQDVQFLQMHEEAEAVLATPPKQPIVDTSAES
1670 1680 1690 1700 1710
>>XP_016864802 (OMIM: 609022) PREDICTED: rapamycin-insen (1679 aa)
initn: 8666 init1: 8666 opt: 8666 Z-score: 9097.5 bits: 1696.4 E(85289): 0
Smith-Waterman score: 10802; 98.6% identity (98.6% similar) in 1679 aa overlap (54-1708:1-1679)
30 40 50 60 70 80
pF1KE2 ENVPLDLTREPSDNLREILQNVARLQGVSNMRKLGHLNNFTKLLCDIGHSEEKLGFHYED
::::::::::::::::::::::::::::::
XP_016 MRKLGHLNNFTKLLCDIGHSEEKLGFHYED
10 20 30
90 100 110 120 130 140
pF1KE2 IIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKVLKLKVDYLIARCIDIQQSNEVER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIICLRLALLNEAKEVRAAGLRALRYLIQDSSILQKVLKLKVDYLIARCIDIQQSNEVER
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE2 TQALRLVRKMITVNASLFPSSVTNSLIAVGNDGLQERDRMVRACIAIICELALQNPEVVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQALRLVRKMITVNASLFPSSVTNSLIAVGNDGLQERDRMVRACIAIICELALQNPEVVA
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE2 LRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKTRQYVRADVELERILAPYTDFHYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRGGLNTILKNVIDCQLSRINEALITTILHLLNHPKTRQYVRADVELERILAPYTDFHYR
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE2 HSPDTAEGQLKEDREARFLASKMGIIATFRSWAGIINLCKPGNSGIQSLIGVLCIPNMEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSPDTAEGQLKEDREARFLASKMGIIATFRSWAGIINLCKPGNSGIQSLIGVLCIPNMEI
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE2 RRGLLEVLYDIFRLPLPVVTEEFIEALLSVDPGRFQDSWRLSDGFVAAEAKTILPHRARS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRGLLEVLYDIFRLPLPVVTEEFIEALLSVDPGRFQDSWRLSDGFVAAEAKTILPHRARS
280 290 300 310 320 330
390 400 410 420 430 440
pF1KE2 RPDLMDNYLALILSAFIRNGLLEGLVEVITNSDDHISVRATILLGELLHMANTILPHSHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPDLMDNYLALILSAFIRNGLLEGLVEVITNSDDHISVRATILLGELLHMANTILPHSHS
340 350 360 370 380 390
450 460 470 480 490 500
pF1KE2 HHLHCLPTLMNMAASFDIPKEKRLRASAALNCLKRFHEMKKRGPKPYSLHLDHIIQKAIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HHLHCLPTLMNMAASFDIPKEKRLRASAALNCLKRFHEMKKRGPKPYSLHLDHIIQKAIA
400 410 420 430 440 450
510 520 530 540 550 560
pF1KE2 THQKRDQYLRVQKDIFILKDTEEALLINLRDSQVLQHKENLEWNWNLIGTILKWPNVNLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 THQKRDQYLRVQKDIFILKDTEEALLINLRDSQVLQHKENLEWNWNLIGTILKWPNVNLR
460 470 480 490 500 510
570 580 590 600 610 620
pF1KE2 NYKDEQLHRFVRRLLYFYKPSSKLYANLDLDFAKAKQLTVVGCQFTEFLLESEEDGQGYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NYKDEQLHRFVRRLLYFYKPSSKLYANLDLDFAKAKQLTVVGCQFTEFLLESEEDGQGYL
520 530 540 550 560 570
630 640 650 660 670 680
pF1KE2 EDLVKDIVQWLNASSGMKPERSLQNNGLLTTLSQHYFLFIGTLSCHPHGVKMLEKCSVFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDLVKDIVQWLNASSGMKPERSLQNNGLLTTLSQHYFLFIGTLSCHPHGVKMLEKCSVFQ
580 590 600 610 620 630
690 700 710 720 730 740
pF1KE2 CLLNLCSLKNQDHLLKLTVSSLDYSRDGLARVILSKILTAATDACRLYATKHLRVLLRAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLLNLCSLKNQDHLLKLTVSSLDYSRDGLARVILSKILTAATDACRLYATKHLRVLLRAN
640 650 660 670 680 690
750 760 770 780 790 800
pF1KE2 VEFFNNWGIELLVTQLHDKNKTISSEALDILDEACEDKANLHALIQMKPALSHLGDKGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEFFNNWGIELLVTQLHDKNKTISSEALDILDEACEDKANLHALIQMKPALSHLGDKGLL
700 710 720 730 740 750
810 820 830 840 850 860
pF1KE2 LLLRFLSIPKGFSYLNERGYVAKQLEKWHREYNSKYVDLIEEQLNEALTTYRKPVDGDNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLLRFLSIPKGFSYLNERGYVAKQLEKWHREYNSKYVDLIEEQLNEALTTYRKPVDGDNY
760 770 780 790 800 810
870 880 890 900 910 920
pF1KE2 VRRSNQRLQRPHVYLPIHLYGQLVHHKTGCHLLEVQNIITELCRNVRTPDLDKWEEIKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRRSNQRLQRPHVYLPIHLYGQLVHHKTGCHLLEVQNIITELCRNVRTPDLDKWEEIKKL
820 830 840 850 860 870
930 940 950 960 970 980
pF1KE2 KASLWALGNIGSSNWGLNLLQEENVIPDILKLAKQCEVLSIRGTCVYVLGLIAKTKQGCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KASLWALGNIGSSNWGLNLLQEENVIPDILKLAKQCEVLSIRGTCVYVLGLIAKTKQGCD
880 890 900 910 920 930
990 1000 1010 1020 1030 1040
pF1KE2 ILKCHNWDAVRHSRKHLWPVVPDDVEQLCNELSSIPSTLSLNSESTSSRHNSESESVPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILKCHNWDAVRHSRKHLWPVVPDDVEQLCNELSSIPSTLSLNSESTSSRHNSESESVPSS
940 950 960 970 980 990
1050 1060 1070 1080 1090 1100
pF1KE2 MFILEDDRFGSSSTSTFFLDINEDTEPTFYDRSGPIKDKNSFPFFASSKLVKNRILNSLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MFILEDDRFGSSSTSTFFLDINEDTEPTFYDRSGPIKDKNSFPFFASSKLVKNRILNSLT
1000 1010 1020 1030 1040 1050
1110 1120 1130 1140 1150 1160
pF1KE2 LPNKKHRSSSDPKGGKLSSESKTSNRRIRTLTEPSVDFNHSDDFTPISTVQKTLQLETSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPNKKHRSSSDPKGGKLSSESKTSNRRIRTLTEPSVDFNHSDDFTPISTVQKTLQLETSF
1060 1070 1080 1090 1100 1110
1170 1180 1190 1200 1210 1220
pF1KE2 MGNKHIEDTGSTPSIGENDLKFTKNFGTENHRENTSRERLVVESSTSSHMKIRSQSFNTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGNKHIEDTGSTPSIGENDLKFTKNFGTENHRENTSRERLVVESSTSSHMKIRSQSFNTD
1120 1130 1140 1150 1160 1170
1230 1240 1250 1260 1270 1280
pF1KE2 TTTSGISSMSSSPSRETVGVDATTMDTDCGSMSTVVSTKTIKTSHYLTPQSNHLSLSKSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTTSGISSMSSSPSRETVGVDATTMDTDCGSMSTVVSTKTIKTSHYLTPQSNHLSLSKSN
1180 1190 1200 1210 1220 1230
1290 1300 1310 1320 1330 1340
pF1KE2 SVSLVPPGSSHTLPRRAQSLKAPSIATIKSLADCNFSYTSSRDAFGYATLKRLQQQRMHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVSLVPPGSSHTLPRRAQSLKAPSIATIKSLADCNFSYTSSRDAFGYATLKRLQQQRMHP
1240 1250 1260 1270 1280 1290
1350 1360 1370
pF1KE2 SLSHSEALASPAKDVLFTDTITMKANSFESRLTPSR------------------------
::::::::::::::::::::::::::::::::::::
XP_016 SLSHSEALASPAKDVLFTDTITMKANSFESRLTPSRIDFKKKHVGGIRSLRPTITNNLFR
1300 1310 1320 1330 1340 1350
1380 1390 1400 1410 1420 1430
pF1KE2 FMKALSYASLDKEDLLSPINQNTLQRSSSVRSMVSSATYGGSDDYIGLALPVDINDIFQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FMKALSYASLDKEDLLSPINQNTLQRSSSVRSMVSSATYGGSDDYIGLALPVDINDIFQV
1360 1370 1380 1390 1400 1410
1440 1450 1460 1470 1480 1490
pF1KE2 KDIPYFQTKNIPPHDDRGARAFAHDAGGLPSGTGGLVKNSFHLLRQQMSLTEIMNSIHSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDIPYFQTKNIPPHDDRGARAFAHDAGGLPSGTGGLVKNSFHLLRQQMSLTEIMNSIHSD
1420 1430 1440 1450 1460 1470
1500 1510 1520 1530 1540 1550
pF1KE2 ASLFLESTEDTGLQEHTDDNCLYCVCIEILGFQPSNQLSAICSHSDFQDIPYSDWCEQTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASLFLESTEDTGLQEHTDDNCLYCVCIEILGFQPSNQLSAICSHSDFQDIPYSDWCEQTI
1480 1490 1500 1510 1520 1530
1560 1570 1580 1590 1600 1610
pF1KE2 HNPLEVVPSKFSGISGCSDGVSQEGSASSTKSTELLLGVKTIPDDTPMCRILLRKEVLRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HNPLEVVPSKFSGISGCSDGVSQEGSASSTKSTELLLGVKTIPDDTPMCRILLRKEVLRL
1540 1550 1560 1570 1580 1590
1620 1630 1640 1650 1660 1670
pF1KE2 VINLSSSVSTKCHETGLLTIKEKYPQTFDDICLYSEVSHLLSHCTFRLPCRRFIQELFQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VINLSSSVSTKCHETGLLTIKEKYPQTFDDICLYSEVSHLLSHCTFRLPCRRFIQELFQD
1600 1610 1620 1630 1640 1650
1680 1690 1700
pF1KE2 VQFLQMHEEAEAVLATPPKQPIVDTSAES
:::::::::::::::::::::::::::::
XP_016 VQFLQMHEEAEAVLATPPKQPIVDTSAES
1660 1670
>>XP_011512308 (OMIM: 609022) PREDICTED: rapamycin-insen (1669 aa)
initn: 8586 init1: 8586 opt: 8586 Z-score: 9013.5 bits: 1680.8 E(85289): 0
Smith-Waterman score: 10722; 98.5% identity (98.6% similar) in 1668 aa overlap (65-1708:2-1669)
40 50 60 70 80 90
pF1KE2 SDNLREILQNVARLQGVSNMRKLGHLNNFTKLLCDIGHSEEKLGFHYEDIIICLRLALLN
.:::::::::::::::::::::::::::::
XP_011 MELLCDIGHSEEKLGFHYEDIIICLRLALLN
10 20 30
100 110 120 130 140 150
pF1KE2 EAKEVRAAGLRALRYLIQDSSILQKVLKLKVDYLIARCIDIQQSNEVERTQALRLVRKMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAKEVRAAGLRALRYLIQDSSILQKVLKLKVDYLIARCIDIQQSNEVERTQALRLVRKMI
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE2 TVNASLFPSSVTNSLIAVGNDGLQERDRMVRACIAIICELALQNPEVVALRGGLNTILKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVNASLFPSSVTNSLIAVGNDGLQERDRMVRACIAIICELALQNPEVVALRGGLNTILKN
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE2 VIDCQLSRINEALITTILHLLNHPKTRQYVRADVELERILAPYTDFHYRHSPDTAEGQLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIDCQLSRINEALITTILHLLNHPKTRQYVRADVELERILAPYTDFHYRHSPDTAEGQLK
160 170 180 190 200 210
280 290 300 310 320 330
pF1KE2 EDREARFLASKMGIIATFRSWAGIINLCKPGNSGIQSLIGVLCIPNMEIRRGLLEVLYDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDREARFLASKMGIIATFRSWAGIINLCKPGNSGIQSLIGVLCIPNMEIRRGLLEVLYDI
220 230 240 250 260 270
340 350 360 370 380 390
pF1KE2 FRLPLPVVTEEFIEALLSVDPGRFQDSWRLSDGFVAAEAKTILPHRARSRPDLMDNYLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FRLPLPVVTEEFIEALLSVDPGRFQDSWRLSDGFVAAEAKTILPHRARSRPDLMDNYLAL
280 290 300 310 320 330
400 410 420 430 440 450
pF1KE2 ILSAFIRNGLLEGLVEVITNSDDHISVRATILLGELLHMANTILPHSHSHHLHCLPTLMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILSAFIRNGLLEGLVEVITNSDDHISVRATILLGELLHMANTILPHSHSHHLHCLPTLMN
340 350 360 370 380 390
460 470 480 490 500 510
pF1KE2 MAASFDIPKEKRLRASAALNCLKRFHEMKKRGPKPYSLHLDHIIQKAIATHQKRDQYLRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAASFDIPKEKRLRASAALNCLKRFHEMKKRGPKPYSLHLDHIIQKAIATHQKRDQYLRV
400 410 420 430 440 450
520 530 540 550 560 570
pF1KE2 QKDIFILKDTEEALLINLRDSQVLQHKENLEWNWNLIGTILKWPNVNLRNYKDEQLHRFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKDIFILKDTEEALLINLRDSQVLQHKENLEWNWNLIGTILKWPNVNLRNYKDEQLHRFV
460 470 480 490 500 510
580 590 600 610 620 630
pF1KE2 RRLLYFYKPSSKLYANLDLDFAKAKQLTVVGCQFTEFLLESEEDGQGYLEDLVKDIVQWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRLLYFYKPSSKLYANLDLDFAKAKQLTVVGCQFTEFLLESEEDGQGYLEDLVKDIVQWL
520 530 540 550 560 570
640 650 660 670 680 690
pF1KE2 NASSGMKPERSLQNNGLLTTLSQHYFLFIGTLSCHPHGVKMLEKCSVFQCLLNLCSLKNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NASSGMKPERSLQNNGLLTTLSQHYFLFIGTLSCHPHGVKMLEKCSVFQCLLNLCSLKNQ
580 590 600 610 620 630
700 710 720 730 740 750
pF1KE2 DHLLKLTVSSLDYSRDGLARVILSKILTAATDACRLYATKHLRVLLRANVEFFNNWGIEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DHLLKLTVSSLDYSRDGLARVILSKILTAATDACRLYATKHLRVLLRANVEFFNNWGIEL
640 650 660 670 680 690
760 770 780 790 800 810
pF1KE2 LVTQLHDKNKTISSEALDILDEACEDKANLHALIQMKPALSHLGDKGLLLLLRFLSIPKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVTQLHDKNKTISSEALDILDEACEDKANLHALIQMKPALSHLGDKGLLLLLRFLSIPKG
700 710 720 730 740 750
820 830 840 850 860 870
pF1KE2 FSYLNERGYVAKQLEKWHREYNSKYVDLIEEQLNEALTTYRKPVDGDNYVRRSNQRLQRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSYLNERGYVAKQLEKWHREYNSKYVDLIEEQLNEALTTYRKPVDGDNYVRRSNQRLQRP
760 770 780 790 800 810
880 890 900 910 920 930
pF1KE2 HVYLPIHLYGQLVHHKTGCHLLEVQNIITELCRNVRTPDLDKWEEIKKLKASLWALGNIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HVYLPIHLYGQLVHHKTGCHLLEVQNIITELCRNVRTPDLDKWEEIKKLKASLWALGNIG
820 830 840 850 860 870
940 950 960 970 980 990
pF1KE2 SSNWGLNLLQEENVIPDILKLAKQCEVLSIRGTCVYVLGLIAKTKQGCDILKCHNWDAVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSNWGLNLLQEENVIPDILKLAKQCEVLSIRGTCVYVLGLIAKTKQGCDILKCHNWDAVR
880 890 900 910 920 930
1000 1010 1020 1030 1040 1050
pF1KE2 HSRKHLWPVVPDDVEQLCNELSSIPSTLSLNSESTSSRHNSESESVPSSMFILEDDRFGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSRKHLWPVVPDDVEQLCNELSSIPSTLSLNSESTSSRHNSESESVPSSMFILEDDRFGS
940 950 960 970 980 990
1060 1070 1080 1090 1100 1110
pF1KE2 SSTSTFFLDINEDTEPTFYDRSGPIKDKNSFPFFASSKLVKNRILNSLTLPNKKHRSSSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSTSTFFLDINEDTEPTFYDRSGPIKDKNSFPFFASSKLVKNRILNSLTLPNKKHRSSSD
1000 1010 1020 1030 1040 1050
1120 1130 1140 1150 1160 1170
pF1KE2 PKGGKLSSESKTSNRRIRTLTEPSVDFNHSDDFTPISTVQKTLQLETSFMGNKHIEDTGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PKGGKLSSESKTSNRRIRTLTEPSVDFNHSDDFTPISTVQKTLQLETSFMGNKHIEDTGS
1060 1070 1080 1090 1100 1110
1180 1190 1200 1210 1220 1230
pF1KE2 TPSIGENDLKFTKNFGTENHRENTSRERLVVESSTSSHMKIRSQSFNTDTTTSGISSMSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPSIGENDLKFTKNFGTENHRENTSRERLVVESSTSSHMKIRSQSFNTDTTTSGISSMSS
1120 1130 1140 1150 1160 1170
1240 1250 1260 1270 1280 1290
pF1KE2 SPSRETVGVDATTMDTDCGSMSTVVSTKTIKTSHYLTPQSNHLSLSKSNSVSLVPPGSSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPSRETVGVDATTMDTDCGSMSTVVSTKTIKTSHYLTPQSNHLSLSKSNSVSLVPPGSSH
1180 1190 1200 1210 1220 1230
1300 1310 1320 1330 1340 1350
pF1KE2 TLPRRAQSLKAPSIATIKSLADCNFSYTSSRDAFGYATLKRLQQQRMHPSLSHSEALASP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLPRRAQSLKAPSIATIKSLADCNFSYTSSRDAFGYATLKRLQQQRMHPSLSHSEALASP
1240 1250 1260 1270 1280 1290
1360 1370 1380 1390
pF1KE2 AKDVLFTDTITMKANSFESRLTPSR------------------------FMKALSYASLD
::::::::::::::::::::::::: :::::::::::
XP_011 AKDVLFTDTITMKANSFESRLTPSRIDFKKKHVGGIRSLRPTITNNLFRFMKALSYASLD
1300 1310 1320 1330 1340 1350
1400 1410 1420 1430 1440 1450
pF1KE2 KEDLLSPINQNTLQRSSSVRSMVSSATYGGSDDYIGLALPVDINDIFQVKDIPYFQTKNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEDLLSPINQNTLQRSSSVRSMVSSATYGGSDDYIGLALPVDINDIFQVKDIPYFQTKNI
1360 1370 1380 1390 1400 1410
1460 1470 1480 1490 1500 1510
pF1KE2 PPHDDRGARAFAHDAGGLPSGTGGLVKNSFHLLRQQMSLTEIMNSIHSDASLFLESTEDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPHDDRGARAFAHDAGGLPSGTGGLVKNSFHLLRQQMSLTEIMNSIHSDASLFLESTEDT
1420 1430 1440 1450 1460 1470
1520 1530 1540 1550 1560 1570
pF1KE2 GLQEHTDDNCLYCVCIEILGFQPSNQLSAICSHSDFQDIPYSDWCEQTIHNPLEVVPSKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLQEHTDDNCLYCVCIEILGFQPSNQLSAICSHSDFQDIPYSDWCEQTIHNPLEVVPSKF
1480 1490 1500 1510 1520 1530
1580 1590 1600 1610 1620 1630
pF1KE2 SGISGCSDGVSQEGSASSTKSTELLLGVKTIPDDTPMCRILLRKEVLRLVINLSSSVSTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGISGCSDGVSQEGSASSTKSTELLLGVKTIPDDTPMCRILLRKEVLRLVINLSSSVSTK
1540 1550 1560 1570 1580 1590
1640 1650 1660 1670 1680 1690
pF1KE2 CHETGLLTIKEKYPQTFDDICLYSEVSHLLSHCTFRLPCRRFIQELFQDVQFLQMHEEAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CHETGLLTIKEKYPQTFDDICLYSEVSHLLSHCTFRLPCRRFIQELFQDVQFLQMHEEAE
1600 1610 1620 1630 1640 1650
1700
pF1KE2 AVLATPPKQPIVDTSAES
::::::::::::::::::
XP_011 AVLATPPKQPIVDTSAES
1660
>>NP_001272369 (OMIM: 609022) rapamycin-insensitive comp (1385 aa)
initn: 7760 init1: 7760 opt: 7760 Z-score: 8147.0 bits: 1520.2 E(85289): 0
Smith-Waterman score: 9050; 97.3% identity (97.3% similar) in 1423 aa overlap (286-1708:1-1385)
260 270 280 290 300 310
pF1KE2 PYTDFHYRHSPDTAEGQLKEDREARFLASKMGIIATFRSWAGIINLCKPGNSGIQSLIGV
::::::::::::::::::::::::::::::
NP_001 MGIIATFRSWAGIINLCKPGNSGIQSLIGV
10 20 30
320 330 340 350 360 370
pF1KE2 LCIPNMEIRRGLLEVLYDIFRLPLPVVTEEFIEALLSVDPGRFQDSWRLSDGFVAAEAKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LCIPNMEIRRGLLEVLYDIFRLPLPVVTEEFIEALLSVDPGRFQDSWRLSDGFVAAEAKT
40 50 60 70 80 90
380 390 400 410 420 430
pF1KE2 ILPHRARSRPDLMDNYLALILSAFIRNGLLEGLVEVITNSDDHISVRATILLGELLHMAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILPHRARSRPDLMDNYLALILSAFIRNGLLEGLVEVITNSDDHISVRATILLGELLHMAN
100 110 120 130 140 150
440 450 460 470 480 490
pF1KE2 TILPHSHSHHLHCLPTLMNMAASFDIPKEKRLRASAALNCLKRFHEMKKRGPKPYSLHLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TILPHSHSHHLHCLPTLMNMAASFDIPKEKRLRASAALNCLKRFHEMKKRGPKPYSLHLD
160 170 180 190 200 210
500 510 520 530 540 550
pF1KE2 HIIQKAIATHQKRDQYLRVQKDIFILKDTEEALLINLRDSQVLQHKENLEWNWNLIGTIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HIIQKAIATHQKRDQYLRVQKDIFILKDTEEALLINLRDSQVLQHKENLEWNWNLIGTIL
220 230 240 250 260 270
560 570 580 590 600 610
pF1KE2 KWPNVNLRNYKDEQLHRFVRRLLYFYKPSSKLYANLDLDFAKAKQLTVVGCQFTEFLLES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KWPNVNLRNYKDEQLHRFVRRLLYFYKPSSKLYANLDLDFAKAKQLTVVGCQFTEFLLES
280 290 300 310 320 330
620 630 640 650 660 670
pF1KE2 EEDGQGYLEDLVKDIVQWLNASSGMKPERSLQNNGLLTTLSQHYFLFIGTLSCHPHGVKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEDGQGYLEDLVKDIVQWLNASSGMKPERSLQNNGLLTTLSQHYFLFIGTLSCHPHGVKM
340 350 360 370 380 390
680 690 700 710 720 730
pF1KE2 LEKCSVFQCLLNLCSLKNQDHLLKLTVSSLDYSRDGLARVILSKILTAATDACRLYATKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEKCSVFQCLLNLCSLKNQDHLLKLTVSSLDYSRDGLARVILSKILTAATDACRLYATKH
400 410 420 430 440 450
740 750 760 770 780 790
pF1KE2 LRVLLRANVEFFNNWGIELLVTQLHDKNKTISSEALDILDEACEDKANLHALIQMKPALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRVLLRANVEFFNNWGIELLVTQLHDKNKTISSEALDILDEACEDKANLHALIQMKPALS
460 470 480 490 500 510
800 810 820 830 840 850
pF1KE2 HLGDKGLLLLLRFLSIPKGFSYLNERGYVAKQLEKWHREYNSKYVDLIEEQLNEALTTYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLGDKGLLLLLRFLSIPKGFSYLNERGYVAKQLEKWHREYNSKYVDLIEEQLNEALTTYR
520 530 540 550 560 570
860 870 880 890 900 910
pF1KE2 KPVDGDNYVRRSNQRLQRPHVYLPIHLYGQLVHHKTGCHLLEVQNIITELCRNVRTPDLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPVDGDNYVRRSNQRLQRPHVYLPIHLYGQLVHHKTGCHLLEVQNIITELCRNVRTPDLD
580 590 600 610 620 630
920 930 940 950 960 970
pF1KE2 KWEEIKKLKASLWALGNIGSSNWGLNLLQEENVIPDILKLAKQCEVLSIRGTCVYVLGLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KWEEIKKLKASLWALGNIGSSNWGLNLLQEENVIPDILKLAKQCEVLSIRGTCVYVLGLI
640 650 660 670 680 690
980 990 1000 1010 1020 1030
pF1KE2 AKTKQGCDILKCHNWDAVRHSRKHLWPVVPDDVEQLCNELSSIPSTLSLNSESTSSRHNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKTKQGCDILKCHNWDAVRHSRKHLWPVVPDDVEQLCNELSSIPSTLSLNSESTSSRHNS
700 710 720 730 740 750
1040 1050 1060 1070 1080 1090
pF1KE2 ESESVPSSMFILEDDRFGSSSTSTFFLDINEDTEPTFYDRSGPIKDKNSFPFFASSKLVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESESVPSSMFILEDDRFGSSSTSTFFLDINEDTEPTFYDRSGPIKDKNSFPFFASSKLVK
760 770 780 790 800 810
1100 1110 1120 1130 1140 1150
pF1KE2 NRILNSLTLPNKKHRSSSDPKGGKLSSESKTSNRRIRTLTEPSVDFNHSDDFTPISTVQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NRILNSLTLPNKKHRSSSDPKGGKLSSESKTSNRRIRTLTEPSVDFNHSDDFTPISTVQK
820 830 840 850 860 870
1160 1170 1180 1190 1200 1210
pF1KE2 TLQLETSFMGNKHIEDTGSTPSIGENDLKFTKNFGTENHRENTSRERLVVESSTSSHMKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLQLETSFMGNKHIEDTGSTPSIGENDLKFTKNFGTENHRENTSRERLVVESSTSSHMKI
880 890 900 910 920 930
1220 1230 1240 1250 1260 1270
pF1KE2 RSQSFNTDTTTSGISSMSSSPSRETVGVDATTMDTDCGSMSTVVSTKTIKTSHYLTPQSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSQSFNTDTTTSGISSMSSSPSRETVGVDATTMDTDCGSMSTVVSTKTIKTSHYLTPQSN
940 950 960 970 980 990
1280 1290 1300 1310 1320 1330
pF1KE2 HLSLSKSNSVSLVPPGSSHTLPRRAQSLKAPSIATIKSLADCNFSYTSSRDAFGYATLKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLSLSKSNSVSLVPPGSSHTLPRRAQSLKAPSIATIKSLADCNFSYTSSRDAFGYATLKR
1000 1010 1020 1030 1040 1050
1340 1350 1360 1370 1380 1390
pF1KE2 LQQQRMHPSLSHSEALASPAKDVLFTDTITMKANSFESRLTPSRFMKALSYASLDKEDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQQQRMHPSLSHSEALASPAKDVLFTDTITMKANSFESRLTPSRFMKALSYASLDKEDLL
1060 1070 1080 1090 1100 1110
1400 1410 1420 1430 1440 1450
pF1KE2 SPINQNTLQRSSSVRSMVSSATYGGSDDYIGLALPVDINDIFQVKDIPYFQTKNIPPHDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPINQNTLQRSSSVRSMVSSATYGGSDDYIGLALPVDINDIFQVKDIPYFQTKNIPPHDD
1120 1130 1140 1150 1160 1170
1460 1470 1480 1490 1500 1510
pF1KE2 RGARAFAHDAGGLPSGTGGLVKNSFHLLRQQMSLTEIMNSIHSDASLFLESTEDTGLQEH
::::::::::: :::::::::::
NP_001 RGARAFAHDAG--------------------------------------ESTEDTGLQEH
1180 1190
1520 1530 1540 1550 1560 1570
pF1KE2 TDDNCLYCVCIEILGFQPSNQLSAICSHSDFQDIPYSDWCEQTIHNPLEVVPSKFSGISG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDDNCLYCVCIEILGFQPSNQLSAICSHSDFQDIPYSDWCEQTIHNPLEVVPSKFSGISG
1200 1210 1220 1230 1240 1250
1580 1590 1600 1610 1620 1630
pF1KE2 CSDGVSQEGSASSTKSTELLLGVKTIPDDTPMCRILLRKEVLRLVINLSSSVSTKCHETG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CSDGVSQEGSASSTKSTELLLGVKTIPDDTPMCRILLRKEVLRLVINLSSSVSTKCHETG
1260 1270 1280 1290 1300 1310
1640 1650 1660 1670 1680 1690
pF1KE2 LLTIKEKYPQTFDDICLYSEVSHLLSHCTFRLPCRRFIQELFQDVQFLQMHEEAEAVLAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLTIKEKYPQTFDDICLYSEVSHLLSHCTFRLPCRRFIQELFQDVQFLQMHEEAEAVLAT
1320 1330 1340 1350 1360 1370
1700
pF1KE2 PPKQPIVDTSAES
:::::::::::::
NP_001 PPKQPIVDTSAES
1380
1708 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 09:35:59 2016 done: Sun Nov 6 09:36:02 2016
Total Scan time: 19.730 Total Display time: 1.090
Function used was FASTA [36.3.4 Apr, 2011]