Result of FASTA (omim) for
pFN21AE2315
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2315, 1101 aa
1>>>pF1KE2315 1101 - 1101 aa - 1101 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.1199+/-0.000517; mu= 17.6213+/- 0.032
mean_var=82.0446+/-16.932, 0's: 0 Z-trim(108.8): 105 B-trim: 0 in 0/49
Lambda= 0.141595
statistics sampled from 16779 (16884) to 16779 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.541), E-opt: 0.2 (0.198), width: 16
Scan time: 9.560
The best scores are: opt bits E(85289)
NP_598375 (OMIM: 606769) helicase POLQ-like isofor (1101) 7140 1469.6 0
XP_005262768 (OMIM: 606769) PREDICTED: helicase PO (1064) 6470 1332.7 0
XP_005262770 (OMIM: 606769) PREDICTED: helicase PO ( 995) 6413 1321.0 0
XP_006714139 (OMIM: 606769) PREDICTED: helicase PO ( 950) 6020 1240.8 0
XP_016863170 (OMIM: 606769) PREDICTED: helicase PO ( 683) 4460 922.0 0
XP_016863169 (OMIM: 606769) PREDICTED: helicase PO ( 928) 4106 849.8 0
XP_016863168 (OMIM: 606769) PREDICTED: helicase PO ( 997) 4106 849.8 0
NP_001284684 (OMIM: 606769) helicase POLQ-like iso (1034) 4106 849.8 0
XP_011529882 (OMIM: 606769) PREDICTED: helicase PO ( 606) 3932 814.1 0
XP_016863171 (OMIM: 606769) PREDICTED: helicase PO ( 604) 3749 776.7 0
NP_001284685 (OMIM: 606769) helicase POLQ-like iso ( 604) 3749 776.7 0
XP_016863172 (OMIM: 606769) PREDICTED: helicase PO ( 604) 3749 776.7 0
NP_001284686 (OMIM: 606769) helicase POLQ-like iso ( 557) 3602 746.7 8.7e-215
NP_001284688 (OMIM: 606769) helicase POLQ-like iso ( 353) 2230 466.3 1.4e-130
NP_001284687 (OMIM: 606769) helicase POLQ-like iso ( 316) 1561 329.7 1.7e-89
XP_011510654 (OMIM: 604419) PREDICTED: DNA polymer (2183) 700 154.1 8.1e-36
XP_011510650 (OMIM: 604419) PREDICTED: DNA polymer (2420) 700 154.2 8.8e-36
XP_011510645 (OMIM: 604419) PREDICTED: DNA polymer (2545) 700 154.2 9.2e-36
NP_955452 (OMIM: 604419) DNA polymerase theta [Hom (2590) 700 154.2 9.4e-36
XP_011510649 (OMIM: 604419) PREDICTED: DNA polymer (2591) 700 154.2 9.4e-36
XP_016861054 (OMIM: 604419) PREDICTED: DNA polymer (2201) 563 126.2 2.2e-27
XP_016855985 (OMIM: 615684,615724) PREDICTED: prob ( 816) 374 87.4 3.8e-16
XP_016855984 (OMIM: 615684,615724) PREDICTED: prob ( 816) 374 87.4 3.8e-16
XP_016855983 (OMIM: 615684,615724) PREDICTED: prob ( 876) 374 87.4 4.1e-16
XP_011539159 (OMIM: 615684,615724) PREDICTED: prob (1294) 374 87.5 5.7e-16
XP_016855980 (OMIM: 615684,615724) PREDICTED: prob (1391) 374 87.5 6.1e-16
XP_011539157 (OMIM: 615684,615724) PREDICTED: prob (1393) 374 87.5 6.1e-16
XP_016855979 (OMIM: 615684,615724) PREDICTED: prob (1408) 374 87.5 6.2e-16
NP_001017975 (OMIM: 615684,615724) probable ATP-de (1435) 374 87.5 6.3e-16
XP_011539152 (OMIM: 615684,615724) PREDICTED: prob (1435) 374 87.5 6.3e-16
XP_011539154 (OMIM: 615684,615724) PREDICTED: prob (1435) 374 87.5 6.3e-16
XP_011539151 (OMIM: 615684,615724) PREDICTED: prob (1435) 374 87.5 6.3e-16
XP_011539153 (OMIM: 615684,615724) PREDICTED: prob (1435) 374 87.5 6.3e-16
XP_016855981 (OMIM: 615684,615724) PREDICTED: prob (1114) 317 75.8 1.6e-12
XP_011539161 (OMIM: 615684,615724) PREDICTED: prob (1044) 302 72.7 1.3e-11
NP_054733 (OMIM: 601664,610359) U5 small nuclear r (2136) 252 62.6 2.8e-08
XP_016859092 (OMIM: 601664,610359) PREDICTED: U5 s (2136) 252 62.6 2.8e-08
XP_016865695 (OMIM: 614217) PREDICTED: activating (1729) 246 61.4 5.5e-08
XP_011533697 (OMIM: 614217) PREDICTED: activating (2104) 246 61.4 6.5e-08
XP_011533698 (OMIM: 614217) PREDICTED: activating (2104) 246 61.4 6.5e-08
XP_016865694 (OMIM: 614217) PREDICTED: activating (2104) 246 61.4 6.5e-08
NP_006819 (OMIM: 614217) activating signal cointeg (2202) 246 61.4 6.8e-08
XP_011533696 (OMIM: 614217) PREDICTED: activating (2207) 246 61.4 6.8e-08
XP_016855982 (OMIM: 615684,615724) PREDICTED: prob ( 878) 227 57.4 4.5e-07
XP_011530405 (OMIM: 613974) PREDICTED: probable AT (1682) 225 57.1 1e-06
NP_060101 (OMIM: 613974) probable ATP-dependent RN (1712) 225 57.1 1.1e-06
XP_011513117 (OMIM: 600478,614602) PREDICTED: heli (1033) 195 50.8 4.8e-05
NP_008860 (OMIM: 600478,614602) helicase SKI2W [Ho (1246) 195 50.9 5.6e-05
XP_016864320 (OMIM: 616725) PREDICTED: probable AT (1093) 191 50.0 8.9e-05
XP_011530711 (OMIM: 616725) PREDICTED: probable AT (1093) 191 50.0 8.9e-05
>>NP_598375 (OMIM: 606769) helicase POLQ-like isoform 1 (1101 aa)
initn: 7140 init1: 7140 opt: 7140 Z-score: 7878.5 bits: 1469.6 E(85289): 0
Smith-Waterman score: 7140; 100.0% identity (100.0% similar) in 1101 aa overlap (1-1101:1-1101)
10 20 30 40 50 60
pF1KE2 MDECGSRIRRRVSLPKRNRPSLGCIFGAPTAAELEPGDEGKEEEEMVAENRRRKTAGVLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 MDECGSRIRRRVSLPKRNRPSLGCIFGAPTAAELEPGDEGKEEEEMVAENRRRKTAGVLP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 VEVQPLLLSDSPECLVLGGGDTNPDLLRHMPTDRGVGDQPNDSEVDMFGDYDSFTENSFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 VEVQPLLLSDSPECLVLGGGDTNPDLLRHMPTDRGVGDQPNDSEVDMFGDYDSFTENSFI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 AQVDDLEQKYMQLPEHKKHATDFATENLCSESIKNKLSITTIGNLTELQTDKHTENQSGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 AQVDDLEQKYMQLPEHKKHATDFATENLCSESIKNKLSITTIGNLTELQTDKHTENQSGY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 EGVTIEPGADLLYDVPSSQAIYFENLQNSSNDLGDHSMKERDWKSSSHNTVNEELPHNCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 EGVTIEPGADLLYDVPSSQAIYFENLQNSSNDLGDHSMKERDWKSSSHNTVNEELPHNCI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 EQPQQNDESSSKVRTSSDMNRRKSIKDHLKNAMTGNAKAQTPIFSRSKQLKDTLLSEEIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 EQPQQNDESSSKVRTSSDMNRRKSIKDHLKNAMTGNAKAQTPIFSRSKQLKDTLLSEEIN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 VAKKTVESSSNDLGPFYSLPSKVRDLYAQFKGIEKLYEWQHTCLTLNSVQERKNLIYSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 VAKKTVESSSNDLGPFYSLPSKVRDLYAQFKGIEKLYEWQHTCLTLNSVQERKNLIYSLP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 TSGGKTLVAEILMLQELLCCRKDVLMILPYVAIVQEKISGLSSFGIELGFFVEEYAGSKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 TSGGKTLVAEILMLQELLCCRKDVLMILPYVAIVQEKISGLSSFGIELGFFVEEYAGSKG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 RFPPTKRREKKSLYIATIEKGHSLVNSLIETGRIDSLGLVVVDELHMIGEGSRGATLEMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 RFPPTKRREKKSLYIATIEKGHSLVNSLIETGRIDSLGLVVVDELHMIGEGSRGATLEMT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 LAKILYTSKTTQIIGMSATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVDSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 LAKILYTSKTTQIIGMSATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVDSK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 AENGMTFSRLLNYKYSDTLKKMDPDHLVALVTEVIPNYSCLVFCPSKKNCENVAEMICKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 AENGMTFSRLLNYKYSDTLKKMDPDHLVALVTEVIPNYSCLVFCPSKKNCENVAEMICKF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 LSKEYLKHKEKEKCEVIKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 LSKEYLKHKEKEKCEVIKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 TGVLCLFTCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDTIGESI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 TGVLCLFTCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDTIGESI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 LILQEKDKQQVLELITKPLENCYSHLVQEFTKGIQTLFLSLIGLKIATNLDDIYHFMNGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 LILQEKDKQQVLELITKPLENCYSHLVQEFTKGIQTLFLSLIGLKIATNLDDIYHFMNGT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 FFGVQQKVLLKEKSLWEITVESLRYLTEKGLLQKDTIYKSEEEVQYNFHITKLGRASFKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 FFGVQQKVLLKEKSLWEITVESLRYLTEKGLLQKDTIYKSEEEVQYNFHITKLGRASFKG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 TIDLAYCDILYRDLKKGLEGLVLESLLHLIYLTTPYDLVSQCNPDWMIYFRQFSQLSPAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 TIDLAYCDILYRDLKKGLEGLVLESLLHLIYLTTPYDLVSQCNPDWMIYFRQFSQLSPAE
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 QNVAAILGVSESFIGKKASGQAIGKKVDKNVVNRLYLSFVLYTLLKETNIWTVSEKFNMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 QNVAAILGVSESFIGKKASGQAIGKKVDKNVVNRLYLSFVLYTLLKETNIWTVSEKFNMP
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 RGYIQNLLTGTASFSSCVLHFCEELEEFWVYRALLVELTKKLTYCVKAELIPLMEVTGVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 RGYIQNLLTGTASFSSCVLHFCEELEEFWVYRALLVELTKKLTYCVKAELIPLMEVTGVL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 EGRAKQLYSAGYKSLMHLANANPEVLVRTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_598 EGRAKQLYSAGYKSLMHLANANPEVLVRTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEV
1030 1040 1050 1060 1070 1080
1090 1100
pF1KE2 EELLRLPSDFPGAVASSTDKA
:::::::::::::::::::::
NP_598 EELLRLPSDFPGAVASSTDKA
1090 1100
>>XP_005262768 (OMIM: 606769) PREDICTED: helicase POLQ-l (1064 aa)
initn: 6464 init1: 6464 opt: 6470 Z-score: 7139.1 bits: 1332.7 E(85289): 0
Smith-Waterman score: 6786; 96.5% identity (96.5% similar) in 1101 aa overlap (1-1101:1-1064)
10 20 30 40 50 60
pF1KE2 MDECGSRIRRRVSLPKRNRPSLGCIFGAPTAAELEPGDEGKEEEEMVAENRRRKTAGVLP
:::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::
XP_005 MDECGSRIRRRVSLPKRNRPSLGCIFGAPTAAELVPGDEGKEEEEMVAENRRRKTAGVLP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 VEVQPLLLSDSPECLVLGGGDTNPDLLRHMPTDRGVGDQPNDSEVDMFGDYDSFTENSFI
:: :::::::::::::::::::::
XP_005 VE-------------------------------------PNDSEVDMFGDYDSFTENSFI
70 80
130 140 150 160 170 180
pF1KE2 AQVDDLEQKYMQLPEHKKHATDFATENLCSESIKNKLSITTIGNLTELQTDKHTENQSGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AQVDDLEQKYMQLPEHKKHATDFATENLCSESIKNKLSITTIGNLTELQTDKHTENQSGY
90 100 110 120 130 140
190 200 210 220 230 240
pF1KE2 EGVTIEPGADLLYDVPSSQAIYFENLQNSSNDLGDHSMKERDWKSSSHNTVNEELPHNCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EGVTIEPGADLLYDVPSSQAIYFENLQNSSNDLGDHSMKERDWKSSSHNTVNEELPHNCI
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE2 EQPQQNDESSSKVRTSSDMNRRKSIKDHLKNAMTGNAKAQTPIFSRSKQLKDTLLSEEIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EQPQQNDESSSKVRTSSDMNRRKSIKDHLKNAMTGNAKAQTPIFSRSKQLKDTLLSEEIN
210 220 230 240 250 260
310 320 330 340 350 360
pF1KE2 VAKKTVESSSNDLGPFYSLPSKVRDLYAQFKGIEKLYEWQHTCLTLNSVQERKNLIYSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VAKKTVESSSNDLGPFYSLPSKVRDLYAQFKGIEKLYEWQHTCLTLNSVQERKNLIYSLP
270 280 290 300 310 320
370 380 390 400 410 420
pF1KE2 TSGGKTLVAEILMLQELLCCRKDVLMILPYVAIVQEKISGLSSFGIELGFFVEEYAGSKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TSGGKTLVAEILMLQELLCCRKDVLMILPYVAIVQEKISGLSSFGIELGFFVEEYAGSKG
330 340 350 360 370 380
430 440 450 460 470 480
pF1KE2 RFPPTKRREKKSLYIATIEKGHSLVNSLIETGRIDSLGLVVVDELHMIGEGSRGATLEMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RFPPTKRREKKSLYIATIEKGHSLVNSLIETGRIDSLGLVVVDELHMIGEGSRGATLEMT
390 400 410 420 430 440
490 500 510 520 530 540
pF1KE2 LAKILYTSKTTQIIGMSATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVDSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LAKILYTSKTTQIIGMSATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVDSK
450 460 470 480 490 500
550 560 570 580 590 600
pF1KE2 AENGMTFSRLLNYKYSDTLKKMDPDHLVALVTEVIPNYSCLVFCPSKKNCENVAEMICKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AENGMTFSRLLNYKYSDTLKKMDPDHLVALVTEVIPNYSCLVFCPSKKNCENVAEMICKF
510 520 530 540 550 560
610 620 630 640 650 660
pF1KE2 LSKEYLKHKEKEKCEVIKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSKEYLKHKEKEKCEVIKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYS
570 580 590 600 610 620
670 680 690 700 710 720
pF1KE2 TGVLCLFTCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDTIGESI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TGVLCLFTCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDTIGESI
630 640 650 660 670 680
730 740 750 760 770 780
pF1KE2 LILQEKDKQQVLELITKPLENCYSHLVQEFTKGIQTLFLSLIGLKIATNLDDIYHFMNGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LILQEKDKQQVLELITKPLENCYSHLVQEFTKGIQTLFLSLIGLKIATNLDDIYHFMNGT
690 700 710 720 730 740
790 800 810 820 830 840
pF1KE2 FFGVQQKVLLKEKSLWEITVESLRYLTEKGLLQKDTIYKSEEEVQYNFHITKLGRASFKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FFGVQQKVLLKEKSLWEITVESLRYLTEKGLLQKDTIYKSEEEVQYNFHITKLGRASFKG
750 760 770 780 790 800
850 860 870 880 890 900
pF1KE2 TIDLAYCDILYRDLKKGLEGLVLESLLHLIYLTTPYDLVSQCNPDWMIYFRQFSQLSPAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TIDLAYCDILYRDLKKGLEGLVLESLLHLIYLTTPYDLVSQCNPDWMIYFRQFSQLSPAE
810 820 830 840 850 860
910 920 930 940 950 960
pF1KE2 QNVAAILGVSESFIGKKASGQAIGKKVDKNVVNRLYLSFVLYTLLKETNIWTVSEKFNMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QNVAAILGVSESFIGKKASGQAIGKKVDKNVVNRLYLSFVLYTLLKETNIWTVSEKFNMP
870 880 890 900 910 920
970 980 990 1000 1010 1020
pF1KE2 RGYIQNLLTGTASFSSCVLHFCEELEEFWVYRALLVELTKKLTYCVKAELIPLMEVTGVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RGYIQNLLTGTASFSSCVLHFCEELEEFWVYRALLVELTKKLTYCVKAELIPLMEVTGVL
930 940 950 960 970 980
1030 1040 1050 1060 1070 1080
pF1KE2 EGRAKQLYSAGYKSLMHLANANPEVLVRTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EGRAKQLYSAGYKSLMHLANANPEVLVRTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEV
990 1000 1010 1020 1030 1040
1090 1100
pF1KE2 EELLRLPSDFPGAVASSTDKA
:::::::::::::::::::::
XP_005 EELLRLPSDFPGAVASSTDKA
1050 1060
>>XP_005262770 (OMIM: 606769) PREDICTED: helicase POLQ-l (995 aa)
initn: 6413 init1: 6413 opt: 6413 Z-score: 7076.6 bits: 1321.0 E(85289): 0
Smith-Waterman score: 6413; 100.0% identity (100.0% similar) in 995 aa overlap (107-1101:1-995)
80 90 100 110 120 130
pF1KE2 LGGGDTNPDLLRHMPTDRGVGDQPNDSEVDMFGDYDSFTENSFIAQVDDLEQKYMQLPEH
::::::::::::::::::::::::::::::
XP_005 MFGDYDSFTENSFIAQVDDLEQKYMQLPEH
10 20 30
140 150 160 170 180 190
pF1KE2 KKHATDFATENLCSESIKNKLSITTIGNLTELQTDKHTENQSGYEGVTIEPGADLLYDVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKHATDFATENLCSESIKNKLSITTIGNLTELQTDKHTENQSGYEGVTIEPGADLLYDVP
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE2 SSQAIYFENLQNSSNDLGDHSMKERDWKSSSHNTVNEELPHNCIEQPQQNDESSSKVRTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSQAIYFENLQNSSNDLGDHSMKERDWKSSSHNTVNEELPHNCIEQPQQNDESSSKVRTS
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE2 SDMNRRKSIKDHLKNAMTGNAKAQTPIFSRSKQLKDTLLSEEINVAKKTVESSSNDLGPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDMNRRKSIKDHLKNAMTGNAKAQTPIFSRSKQLKDTLLSEEINVAKKTVESSSNDLGPF
160 170 180 190 200 210
320 330 340 350 360 370
pF1KE2 YSLPSKVRDLYAQFKGIEKLYEWQHTCLTLNSVQERKNLIYSLPTSGGKTLVAEILMLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YSLPSKVRDLYAQFKGIEKLYEWQHTCLTLNSVQERKNLIYSLPTSGGKTLVAEILMLQE
220 230 240 250 260 270
380 390 400 410 420 430
pF1KE2 LLCCRKDVLMILPYVAIVQEKISGLSSFGIELGFFVEEYAGSKGRFPPTKRREKKSLYIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLCCRKDVLMILPYVAIVQEKISGLSSFGIELGFFVEEYAGSKGRFPPTKRREKKSLYIA
280 290 300 310 320 330
440 450 460 470 480 490
pF1KE2 TIEKGHSLVNSLIETGRIDSLGLVVVDELHMIGEGSRGATLEMTLAKILYTSKTTQIIGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TIEKGHSLVNSLIETGRIDSLGLVVVDELHMIGEGSRGATLEMTLAKILYTSKTTQIIGM
340 350 360 370 380 390
500 510 520 530 540 550
pF1KE2 SATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVDSKAENGMTFSRLLNYKYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVDSKAENGMTFSRLLNYKYS
400 410 420 430 440 450
560 570 580 590 600 610
pF1KE2 DTLKKMDPDHLVALVTEVIPNYSCLVFCPSKKNCENVAEMICKFLSKEYLKHKEKEKCEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DTLKKMDPDHLVALVTEVIPNYSCLVFCPSKKNCENVAEMICKFLSKEYLKHKEKEKCEV
460 470 480 490 500 510
620 630 640 650 660 670
pF1KE2 IKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYSTGVLCLFTCTSTLAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYSTGVLCLFTCTSTLAAG
520 530 540 550 560 570
680 690 700 710 720 730
pF1KE2 VNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDTIGESILILQEKDKQQVLELIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDTIGESILILQEKDKQQVLELIT
580 590 600 610 620 630
740 750 760 770 780 790
pF1KE2 KPLENCYSHLVQEFTKGIQTLFLSLIGLKIATNLDDIYHFMNGTFFGVQQKVLLKEKSLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KPLENCYSHLVQEFTKGIQTLFLSLIGLKIATNLDDIYHFMNGTFFGVQQKVLLKEKSLW
640 650 660 670 680 690
800 810 820 830 840 850
pF1KE2 EITVESLRYLTEKGLLQKDTIYKSEEEVQYNFHITKLGRASFKGTIDLAYCDILYRDLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EITVESLRYLTEKGLLQKDTIYKSEEEVQYNFHITKLGRASFKGTIDLAYCDILYRDLKK
700 710 720 730 740 750
860 870 880 890 900 910
pF1KE2 GLEGLVLESLLHLIYLTTPYDLVSQCNPDWMIYFRQFSQLSPAEQNVAAILGVSESFIGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLEGLVLESLLHLIYLTTPYDLVSQCNPDWMIYFRQFSQLSPAEQNVAAILGVSESFIGK
760 770 780 790 800 810
920 930 940 950 960 970
pF1KE2 KASGQAIGKKVDKNVVNRLYLSFVLYTLLKETNIWTVSEKFNMPRGYIQNLLTGTASFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KASGQAIGKKVDKNVVNRLYLSFVLYTLLKETNIWTVSEKFNMPRGYIQNLLTGTASFSS
820 830 840 850 860 870
980 990 1000 1010 1020 1030
pF1KE2 CVLHFCEELEEFWVYRALLVELTKKLTYCVKAELIPLMEVTGVLEGRAKQLYSAGYKSLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CVLHFCEELEEFWVYRALLVELTKKLTYCVKAELIPLMEVTGVLEGRAKQLYSAGYKSLM
880 890 900 910 920 930
1040 1050 1060 1070 1080 1090
pF1KE2 HLANANPEVLVRTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEVEELLRLPSDFPGAVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HLANANPEVLVRTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEVEELLRLPSDFPGAVAS
940 950 960 970 980 990
1100
pF1KE2 STDKA
:::::
XP_005 STDKA
>>XP_006714139 (OMIM: 606769) PREDICTED: helicase POLQ-l (950 aa)
initn: 6020 init1: 6020 opt: 6020 Z-score: 6643.0 bits: 1240.8 E(85289): 0
Smith-Waterman score: 6020; 99.7% identity (99.9% similar) in 927 aa overlap (1-927:1-927)
10 20 30 40 50 60
pF1KE2 MDECGSRIRRRVSLPKRNRPSLGCIFGAPTAAELEPGDEGKEEEEMVAENRRRKTAGVLP
:::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::
XP_006 MDECGSRIRRRVSLPKRNRPSLGCIFGAPTAAELVPGDEGKEEEEMVAENRRRKTAGVLP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 VEVQPLLLSDSPECLVLGGGDTNPDLLRHMPTDRGVGDQPNDSEVDMFGDYDSFTENSFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VEVQPLLLSDSPECLVLGGGDTNPDLLRHMPTDRGVGDQPNDSEVDMFGDYDSFTENSFI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 AQVDDLEQKYMQLPEHKKHATDFATENLCSESIKNKLSITTIGNLTELQTDKHTENQSGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AQVDDLEQKYMQLPEHKKHATDFATENLCSESIKNKLSITTIGNLTELQTDKHTENQSGY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 EGVTIEPGADLLYDVPSSQAIYFENLQNSSNDLGDHSMKERDWKSSSHNTVNEELPHNCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EGVTIEPGADLLYDVPSSQAIYFENLQNSSNDLGDHSMKERDWKSSSHNTVNEELPHNCI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 EQPQQNDESSSKVRTSSDMNRRKSIKDHLKNAMTGNAKAQTPIFSRSKQLKDTLLSEEIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EQPQQNDESSSKVRTSSDMNRRKSIKDHLKNAMTGNAKAQTPIFSRSKQLKDTLLSEEIN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 VAKKTVESSSNDLGPFYSLPSKVRDLYAQFKGIEKLYEWQHTCLTLNSVQERKNLIYSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VAKKTVESSSNDLGPFYSLPSKVRDLYAQFKGIEKLYEWQHTCLTLNSVQERKNLIYSLP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 TSGGKTLVAEILMLQELLCCRKDVLMILPYVAIVQEKISGLSSFGIELGFFVEEYAGSKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TSGGKTLVAEILMLQELLCCRKDVLMILPYVAIVQEKISGLSSFGIELGFFVEEYAGSKG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 RFPPTKRREKKSLYIATIEKGHSLVNSLIETGRIDSLGLVVVDELHMIGEGSRGATLEMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RFPPTKRREKKSLYIATIEKGHSLVNSLIETGRIDSLGLVVVDELHMIGEGSRGATLEMT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 LAKILYTSKTTQIIGMSATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVDSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LAKILYTSKTTQIIGMSATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVDSK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 AENGMTFSRLLNYKYSDTLKKMDPDHLVALVTEVIPNYSCLVFCPSKKNCENVAEMICKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AENGMTFSRLLNYKYSDTLKKMDPDHLVALVTEVIPNYSCLVFCPSKKNCENVAEMICKF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 LSKEYLKHKEKEKCEVIKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LSKEYLKHKEKEKCEVIKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 TGVLCLFTCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDTIGESI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TGVLCLFTCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDTIGESI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 LILQEKDKQQVLELITKPLENCYSHLVQEFTKGIQTLFLSLIGLKIATNLDDIYHFMNGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LILQEKDKQQVLELITKPLENCYSHLVQEFTKGIQTLFLSLIGLKIATNLDDIYHFMNGT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 FFGVQQKVLLKEKSLWEITVESLRYLTEKGLLQKDTIYKSEEEVQYNFHITKLGRASFKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FFGVQQKVLLKEKSLWEITVESLRYLTEKGLLQKDTIYKSEEEVQYNFHITKLGRASFKG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 TIDLAYCDILYRDLKKGLEGLVLESLLHLIYLTTPYDLVSQCNPDWMIYFRQFSQLSPAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TIDLAYCDILYRDLKKGLEGLVLESLLHLIYLTTPYDLVSQCNPDWMIYFRQFSQLSPAE
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 QNVAAILGVSESFIGKKASGQAIGKKVDKNVVNRLYLSFVLYTLLKETNIWTVSEKFNMP
:::::::::::::::::::::::::..
XP_006 QNVAAILGVSESFIGKKASGQAIGKEIHSKKKPTLTQFIVSTEDALKLGN
910 920 930 940 950
>>XP_016863170 (OMIM: 606769) PREDICTED: helicase POLQ-l (683 aa)
initn: 4460 init1: 4460 opt: 4460 Z-score: 4923.0 bits: 922.0 E(85289): 0
Smith-Waterman score: 4460; 99.9% identity (99.9% similar) in 683 aa overlap (1-683:1-683)
10 20 30 40 50 60
pF1KE2 MDECGSRIRRRVSLPKRNRPSLGCIFGAPTAAELEPGDEGKEEEEMVAENRRRKTAGVLP
:::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::
XP_016 MDECGSRIRRRVSLPKRNRPSLGCIFGAPTAAELVPGDEGKEEEEMVAENRRRKTAGVLP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 VEVQPLLLSDSPECLVLGGGDTNPDLLRHMPTDRGVGDQPNDSEVDMFGDYDSFTENSFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEVQPLLLSDSPECLVLGGGDTNPDLLRHMPTDRGVGDQPNDSEVDMFGDYDSFTENSFI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 AQVDDLEQKYMQLPEHKKHATDFATENLCSESIKNKLSITTIGNLTELQTDKHTENQSGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQVDDLEQKYMQLPEHKKHATDFATENLCSESIKNKLSITTIGNLTELQTDKHTENQSGY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 EGVTIEPGADLLYDVPSSQAIYFENLQNSSNDLGDHSMKERDWKSSSHNTVNEELPHNCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGVTIEPGADLLYDVPSSQAIYFENLQNSSNDLGDHSMKERDWKSSSHNTVNEELPHNCI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 EQPQQNDESSSKVRTSSDMNRRKSIKDHLKNAMTGNAKAQTPIFSRSKQLKDTLLSEEIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQPQQNDESSSKVRTSSDMNRRKSIKDHLKNAMTGNAKAQTPIFSRSKQLKDTLLSEEIN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 VAKKTVESSSNDLGPFYSLPSKVRDLYAQFKGIEKLYEWQHTCLTLNSVQERKNLIYSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAKKTVESSSNDLGPFYSLPSKVRDLYAQFKGIEKLYEWQHTCLTLNSVQERKNLIYSLP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 TSGGKTLVAEILMLQELLCCRKDVLMILPYVAIVQEKISGLSSFGIELGFFVEEYAGSKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSGGKTLVAEILMLQELLCCRKDVLMILPYVAIVQEKISGLSSFGIELGFFVEEYAGSKG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 RFPPTKRREKKSLYIATIEKGHSLVNSLIETGRIDSLGLVVVDELHMIGEGSRGATLEMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFPPTKRREKKSLYIATIEKGHSLVNSLIETGRIDSLGLVVVDELHMIGEGSRGATLEMT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 LAKILYTSKTTQIIGMSATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVDSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAKILYTSKTTQIIGMSATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVDSK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 AENGMTFSRLLNYKYSDTLKKMDPDHLVALVTEVIPNYSCLVFCPSKKNCENVAEMICKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AENGMTFSRLLNYKYSDTLKKMDPDHLVALVTEVIPNYSCLVFCPSKKNCENVAEMICKF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 LSKEYLKHKEKEKCEVIKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSKEYLKHKEKEKCEVIKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 TGVLCLFTCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDTIGESI
:::::::::::::::::::::::
XP_016 TGVLCLFTCTSTLAAGVNLPARR
670 680
>>XP_016863169 (OMIM: 606769) PREDICTED: helicase POLQ-l (928 aa)
initn: 4106 init1: 4106 opt: 4106 Z-score: 4530.1 bits: 849.8 E(85289): 0
Smith-Waterman score: 5849; 93.3% identity (93.3% similar) in 995 aa overlap (107-1101:1-928)
80 90 100 110 120 130
pF1KE2 LGGGDTNPDLLRHMPTDRGVGDQPNDSEVDMFGDYDSFTENSFIAQVDDLEQKYMQLPEH
::::::::::::::::::::::::::::::
XP_016 MFGDYDSFTENSFIAQVDDLEQKYMQLPEH
10 20 30
140 150 160 170 180 190
pF1KE2 KKHATDFATENLCSESIKNKLSITTIGNLTELQTDKHTENQSGYEGVTIEPGADLLYDVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKHATDFATENLCSESIKNKLSITTIGNLTELQTDKHTENQSGYEGVTIEPGADLLYDVP
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE2 SSQAIYFENLQNSSNDLGDHSMKERDWKSSSHNTVNEELPHNCIEQPQQNDESSSKVRTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSQAIYFENLQNSSNDLGDHSMKERDWKSSSHNTVNEELPHNCIEQPQQNDESSSKVRTS
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE2 SDMNRRKSIKDHLKNAMTGNAKAQTPIFSRSKQLKDTLLSEEINVAKKTVESSSNDLGPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDMNRRKSIKDHLKNAMTGNAKAQTPIFSRSKQLKDTLLSEEINVAKKTVESSSNDLGPF
160 170 180 190 200 210
320 330 340 350 360 370
pF1KE2 YSLPSKVRDLYAQFKGIEKLYEWQHTCLTLNSVQERKNLIYSLPTSGGKTLVAEILMLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YSLPSKVRDLYAQFKGIEKLYEWQHTCLTLNSVQERKNLIYSLPTSGGKTLVAEILMLQE
220 230 240 250 260 270
380 390 400 410 420 430
pF1KE2 LLCCRKDVLMILPYVAIVQEKISGLSSFGIELGFFVEEYAGSKGRFPPTKRREKKSLYIA
:::::::::::::::::::::
XP_016 LLCCRKDVLMILPYVAIVQEK---------------------------------------
280 290
440 450 460 470 480 490
pF1KE2 TIEKGHSLVNSLIETGRIDSLGLVVVDELHMIGEGSRGATLEMTLAKILYTSKTTQIIGM
::::::::::::::::::::::::::::::::
XP_016 ----------------------------LHMIGEGSRGATLEMTLAKILYTSKTTQIIGM
300 310 320
500 510 520 530 540 550
pF1KE2 SATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVDSKAENGMTFSRLLNYKYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVDSKAENGMTFSRLLNYKYS
330 340 350 360 370 380
560 570 580 590 600 610
pF1KE2 DTLKKMDPDHLVALVTEVIPNYSCLVFCPSKKNCENVAEMICKFLSKEYLKHKEKEKCEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTLKKMDPDHLVALVTEVIPNYSCLVFCPSKKNCENVAEMICKFLSKEYLKHKEKEKCEV
390 400 410 420 430 440
620 630 640 650 660 670
pF1KE2 IKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYSTGVLCLFTCTSTLAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYSTGVLCLFTCTSTLAAG
450 460 470 480 490 500
680 690 700 710 720 730
pF1KE2 VNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDTIGESILILQEKDKQQVLELIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDTIGESILILQEKDKQQVLELIT
510 520 530 540 550 560
740 750 760 770 780 790
pF1KE2 KPLENCYSHLVQEFTKGIQTLFLSLIGLKIATNLDDIYHFMNGTFFGVQQKVLLKEKSLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPLENCYSHLVQEFTKGIQTLFLSLIGLKIATNLDDIYHFMNGTFFGVQQKVLLKEKSLW
570 580 590 600 610 620
800 810 820 830 840 850
pF1KE2 EITVESLRYLTEKGLLQKDTIYKSEEEVQYNFHITKLGRASFKGTIDLAYCDILYRDLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EITVESLRYLTEKGLLQKDTIYKSEEEVQYNFHITKLGRASFKGTIDLAYCDILYRDLKK
630 640 650 660 670 680
860 870 880 890 900 910
pF1KE2 GLEGLVLESLLHLIYLTTPYDLVSQCNPDWMIYFRQFSQLSPAEQNVAAILGVSESFIGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLEGLVLESLLHLIYLTTPYDLVSQCNPDWMIYFRQFSQLSPAEQNVAAILGVSESFIGK
690 700 710 720 730 740
920 930 940 950 960 970
pF1KE2 KASGQAIGKKVDKNVVNRLYLSFVLYTLLKETNIWTVSEKFNMPRGYIQNLLTGTASFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KASGQAIGKKVDKNVVNRLYLSFVLYTLLKETNIWTVSEKFNMPRGYIQNLLTGTASFSS
750 760 770 780 790 800
980 990 1000 1010 1020 1030
pF1KE2 CVLHFCEELEEFWVYRALLVELTKKLTYCVKAELIPLMEVTGVLEGRAKQLYSAGYKSLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CVLHFCEELEEFWVYRALLVELTKKLTYCVKAELIPLMEVTGVLEGRAKQLYSAGYKSLM
810 820 830 840 850 860
1040 1050 1060 1070 1080 1090
pF1KE2 HLANANPEVLVRTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEVEELLRLPSDFPGAVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLANANPEVLVRTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEVEELLRLPSDFPGAVAS
870 880 890 900 910 920
1100
pF1KE2 STDKA
:::::
XP_016 STDKA
>>XP_016863168 (OMIM: 606769) PREDICTED: helicase POLQ-l (997 aa)
initn: 4500 init1: 4106 opt: 4106 Z-score: 4529.6 bits: 849.8 E(85289): 0
Smith-Waterman score: 6222; 90.5% identity (90.5% similar) in 1101 aa overlap (1-1101:1-997)
10 20 30 40 50 60
pF1KE2 MDECGSRIRRRVSLPKRNRPSLGCIFGAPTAAELEPGDEGKEEEEMVAENRRRKTAGVLP
:::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::
XP_016 MDECGSRIRRRVSLPKRNRPSLGCIFGAPTAAELVPGDEGKEEEEMVAENRRRKTAGVLP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 VEVQPLLLSDSPECLVLGGGDTNPDLLRHMPTDRGVGDQPNDSEVDMFGDYDSFTENSFI
:: :::::::::::::::::::::
XP_016 VE-------------------------------------PNDSEVDMFGDYDSFTENSFI
70 80
130 140 150 160 170 180
pF1KE2 AQVDDLEQKYMQLPEHKKHATDFATENLCSESIKNKLSITTIGNLTELQTDKHTENQSGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQVDDLEQKYMQLPEHKKHATDFATENLCSESIKNKLSITTIGNLTELQTDKHTENQSGY
90 100 110 120 130 140
190 200 210 220 230 240
pF1KE2 EGVTIEPGADLLYDVPSSQAIYFENLQNSSNDLGDHSMKERDWKSSSHNTVNEELPHNCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGVTIEPGADLLYDVPSSQAIYFENLQNSSNDLGDHSMKERDWKSSSHNTVNEELPHNCI
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE2 EQPQQNDESSSKVRTSSDMNRRKSIKDHLKNAMTGNAKAQTPIFSRSKQLKDTLLSEEIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQPQQNDESSSKVRTSSDMNRRKSIKDHLKNAMTGNAKAQTPIFSRSKQLKDTLLSEEIN
210 220 230 240 250 260
310 320 330 340 350 360
pF1KE2 VAKKTVESSSNDLGPFYSLPSKVRDLYAQFKGIEKLYEWQHTCLTLNSVQERKNLIYSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAKKTVESSSNDLGPFYSLPSKVRDLYAQFKGIEKLYEWQHTCLTLNSVQERKNLIYSLP
270 280 290 300 310 320
370 380 390 400 410 420
pF1KE2 TSGGKTLVAEILMLQELLCCRKDVLMILPYVAIVQEKISGLSSFGIELGFFVEEYAGSKG
:::::::::::::::::::::::::::::::::::::
XP_016 TSGGKTLVAEILMLQELLCCRKDVLMILPYVAIVQEK-----------------------
330 340 350 360
430 440 450 460 470 480
pF1KE2 RFPPTKRREKKSLYIATIEKGHSLVNSLIETGRIDSLGLVVVDELHMIGEGSRGATLEMT
::::::::::::::::
XP_016 --------------------------------------------LHMIGEGSRGATLEMT
370
490 500 510 520 530 540
pF1KE2 LAKILYTSKTTQIIGMSATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVDSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAKILYTSKTTQIIGMSATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVDSK
380 390 400 410 420 430
550 560 570 580 590 600
pF1KE2 AENGMTFSRLLNYKYSDTLKKMDPDHLVALVTEVIPNYSCLVFCPSKKNCENVAEMICKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AENGMTFSRLLNYKYSDTLKKMDPDHLVALVTEVIPNYSCLVFCPSKKNCENVAEMICKF
440 450 460 470 480 490
610 620 630 640 650 660
pF1KE2 LSKEYLKHKEKEKCEVIKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSKEYLKHKEKEKCEVIKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYS
500 510 520 530 540 550
670 680 690 700 710 720
pF1KE2 TGVLCLFTCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDTIGESI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGVLCLFTCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDTIGESI
560 570 580 590 600 610
730 740 750 760 770 780
pF1KE2 LILQEKDKQQVLELITKPLENCYSHLVQEFTKGIQTLFLSLIGLKIATNLDDIYHFMNGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LILQEKDKQQVLELITKPLENCYSHLVQEFTKGIQTLFLSLIGLKIATNLDDIYHFMNGT
620 630 640 650 660 670
790 800 810 820 830 840
pF1KE2 FFGVQQKVLLKEKSLWEITVESLRYLTEKGLLQKDTIYKSEEEVQYNFHITKLGRASFKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FFGVQQKVLLKEKSLWEITVESLRYLTEKGLLQKDTIYKSEEEVQYNFHITKLGRASFKG
680 690 700 710 720 730
850 860 870 880 890 900
pF1KE2 TIDLAYCDILYRDLKKGLEGLVLESLLHLIYLTTPYDLVSQCNPDWMIYFRQFSQLSPAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIDLAYCDILYRDLKKGLEGLVLESLLHLIYLTTPYDLVSQCNPDWMIYFRQFSQLSPAE
740 750 760 770 780 790
910 920 930 940 950 960
pF1KE2 QNVAAILGVSESFIGKKASGQAIGKKVDKNVVNRLYLSFVLYTLLKETNIWTVSEKFNMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNVAAILGVSESFIGKKASGQAIGKKVDKNVVNRLYLSFVLYTLLKETNIWTVSEKFNMP
800 810 820 830 840 850
970 980 990 1000 1010 1020
pF1KE2 RGYIQNLLTGTASFSSCVLHFCEELEEFWVYRALLVELTKKLTYCVKAELIPLMEVTGVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGYIQNLLTGTASFSSCVLHFCEELEEFWVYRALLVELTKKLTYCVKAELIPLMEVTGVL
860 870 880 890 900 910
1030 1040 1050 1060 1070 1080
pF1KE2 EGRAKQLYSAGYKSLMHLANANPEVLVRTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGRAKQLYSAGYKSLMHLANANPEVLVRTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEV
920 930 940 950 960 970
1090 1100
pF1KE2 EELLRLPSDFPGAVASSTDKA
:::::::::::::::::::::
XP_016 EELLRLPSDFPGAVASSTDKA
980 990
>>NP_001284684 (OMIM: 606769) helicase POLQ-like isoform (1034 aa)
initn: 4106 init1: 4106 opt: 4106 Z-score: 4529.4 bits: 849.8 E(85289): 0
Smith-Waterman score: 6576; 93.9% identity (93.9% similar) in 1101 aa overlap (1-1101:1-1034)
10 20 30 40 50 60
pF1KE2 MDECGSRIRRRVSLPKRNRPSLGCIFGAPTAAELEPGDEGKEEEEMVAENRRRKTAGVLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDECGSRIRRRVSLPKRNRPSLGCIFGAPTAAELEPGDEGKEEEEMVAENRRRKTAGVLP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 VEVQPLLLSDSPECLVLGGGDTNPDLLRHMPTDRGVGDQPNDSEVDMFGDYDSFTENSFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEVQPLLLSDSPECLVLGGGDTNPDLLRHMPTDRGVGDQPNDSEVDMFGDYDSFTENSFI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 AQVDDLEQKYMQLPEHKKHATDFATENLCSESIKNKLSITTIGNLTELQTDKHTENQSGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQVDDLEQKYMQLPEHKKHATDFATENLCSESIKNKLSITTIGNLTELQTDKHTENQSGY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 EGVTIEPGADLLYDVPSSQAIYFENLQNSSNDLGDHSMKERDWKSSSHNTVNEELPHNCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGVTIEPGADLLYDVPSSQAIYFENLQNSSNDLGDHSMKERDWKSSSHNTVNEELPHNCI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 EQPQQNDESSSKVRTSSDMNRRKSIKDHLKNAMTGNAKAQTPIFSRSKQLKDTLLSEEIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQPQQNDESSSKVRTSSDMNRRKSIKDHLKNAMTGNAKAQTPIFSRSKQLKDTLLSEEIN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 VAKKTVESSSNDLGPFYSLPSKVRDLYAQFKGIEKLYEWQHTCLTLNSVQERKNLIYSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAKKTVESSSNDLGPFYSLPSKVRDLYAQFKGIEKLYEWQHTCLTLNSVQERKNLIYSLP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 TSGGKTLVAEILMLQELLCCRKDVLMILPYVAIVQEKISGLSSFGIELGFFVEEYAGSKG
:::::::::::::::::::::::::::::::::::::
NP_001 TSGGKTLVAEILMLQELLCCRKDVLMILPYVAIVQEK-----------------------
370 380 390
430 440 450 460 470 480
pF1KE2 RFPPTKRREKKSLYIATIEKGHSLVNSLIETGRIDSLGLVVVDELHMIGEGSRGATLEMT
::::::::::::::::
NP_001 --------------------------------------------LHMIGEGSRGATLEMT
400 410
490 500 510 520 530 540
pF1KE2 LAKILYTSKTTQIIGMSATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVDSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAKILYTSKTTQIIGMSATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVDSK
420 430 440 450 460 470
550 560 570 580 590 600
pF1KE2 AENGMTFSRLLNYKYSDTLKKMDPDHLVALVTEVIPNYSCLVFCPSKKNCENVAEMICKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AENGMTFSRLLNYKYSDTLKKMDPDHLVALVTEVIPNYSCLVFCPSKKNCENVAEMICKF
480 490 500 510 520 530
610 620 630 640 650 660
pF1KE2 LSKEYLKHKEKEKCEVIKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSKEYLKHKEKEKCEVIKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYS
540 550 560 570 580 590
670 680 690 700 710 720
pF1KE2 TGVLCLFTCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDTIGESI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGVLCLFTCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDTIGESI
600 610 620 630 640 650
730 740 750 760 770 780
pF1KE2 LILQEKDKQQVLELITKPLENCYSHLVQEFTKGIQTLFLSLIGLKIATNLDDIYHFMNGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LILQEKDKQQVLELITKPLENCYSHLVQEFTKGIQTLFLSLIGLKIATNLDDIYHFMNGT
660 670 680 690 700 710
790 800 810 820 830 840
pF1KE2 FFGVQQKVLLKEKSLWEITVESLRYLTEKGLLQKDTIYKSEEEVQYNFHITKLGRASFKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFGVQQKVLLKEKSLWEITVESLRYLTEKGLLQKDTIYKSEEEVQYNFHITKLGRASFKG
720 730 740 750 760 770
850 860 870 880 890 900
pF1KE2 TIDLAYCDILYRDLKKGLEGLVLESLLHLIYLTTPYDLVSQCNPDWMIYFRQFSQLSPAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIDLAYCDILYRDLKKGLEGLVLESLLHLIYLTTPYDLVSQCNPDWMIYFRQFSQLSPAE
780 790 800 810 820 830
910 920 930 940 950 960
pF1KE2 QNVAAILGVSESFIGKKASGQAIGKKVDKNVVNRLYLSFVLYTLLKETNIWTVSEKFNMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QNVAAILGVSESFIGKKASGQAIGKKVDKNVVNRLYLSFVLYTLLKETNIWTVSEKFNMP
840 850 860 870 880 890
970 980 990 1000 1010 1020
pF1KE2 RGYIQNLLTGTASFSSCVLHFCEELEEFWVYRALLVELTKKLTYCVKAELIPLMEVTGVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGYIQNLLTGTASFSSCVLHFCEELEEFWVYRALLVELTKKLTYCVKAELIPLMEVTGVL
900 910 920 930 940 950
1030 1040 1050 1060 1070 1080
pF1KE2 EGRAKQLYSAGYKSLMHLANANPEVLVRTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGRAKQLYSAGYKSLMHLANANPEVLVRTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEV
960 970 980 990 1000 1010
1090 1100
pF1KE2 EELLRLPSDFPGAVASSTDKA
:::::::::::::::::::::
NP_001 EELLRLPSDFPGAVASSTDKA
1020 1030
>>XP_011529882 (OMIM: 606769) PREDICTED: helicase POLQ-l (606 aa)
initn: 3961 init1: 3932 opt: 3932 Z-score: 4340.9 bits: 814.1 E(85289): 0
Smith-Waterman score: 3932; 99.5% identity (99.7% similar) in 605 aa overlap (1-605:1-605)
10 20 30 40 50 60
pF1KE2 MDECGSRIRRRVSLPKRNRPSLGCIFGAPTAAELEPGDEGKEEEEMVAENRRRKTAGVLP
:::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::
XP_011 MDECGSRIRRRVSLPKRNRPSLGCIFGAPTAAELVPGDEGKEEEEMVAENRRRKTAGVLP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 VEVQPLLLSDSPECLVLGGGDTNPDLLRHMPTDRGVGDQPNDSEVDMFGDYDSFTENSFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEVQPLLLSDSPECLVLGGGDTNPDLLRHMPTDRGVGDQPNDSEVDMFGDYDSFTENSFI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 AQVDDLEQKYMQLPEHKKHATDFATENLCSESIKNKLSITTIGNLTELQTDKHTENQSGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQVDDLEQKYMQLPEHKKHATDFATENLCSESIKNKLSITTIGNLTELQTDKHTENQSGY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 EGVTIEPGADLLYDVPSSQAIYFENLQNSSNDLGDHSMKERDWKSSSHNTVNEELPHNCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGVTIEPGADLLYDVPSSQAIYFENLQNSSNDLGDHSMKERDWKSSSHNTVNEELPHNCI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 EQPQQNDESSSKVRTSSDMNRRKSIKDHLKNAMTGNAKAQTPIFSRSKQLKDTLLSEEIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQPQQNDESSSKVRTSSDMNRRKSIKDHLKNAMTGNAKAQTPIFSRSKQLKDTLLSEEIN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 VAKKTVESSSNDLGPFYSLPSKVRDLYAQFKGIEKLYEWQHTCLTLNSVQERKNLIYSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAKKTVESSSNDLGPFYSLPSKVRDLYAQFKGIEKLYEWQHTCLTLNSVQERKNLIYSLP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 TSGGKTLVAEILMLQELLCCRKDVLMILPYVAIVQEKISGLSSFGIELGFFVEEYAGSKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSGGKTLVAEILMLQELLCCRKDVLMILPYVAIVQEKISGLSSFGIELGFFVEEYAGSKG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 RFPPTKRREKKSLYIATIEKGHSLVNSLIETGRIDSLGLVVVDELHMIGEGSRGATLEMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFPPTKRREKKSLYIATIEKGHSLVNSLIETGRIDSLGLVVVDELHMIGEGSRGATLEMT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 LAKILYTSKTTQIIGMSATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVDSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAKILYTSKTTQIIGMSATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVDSK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 AENGMTFSRLLNYKYSDTLKKMDPDHLVALVTEVIPNYSCLVFCPSKKNCENVAEMICKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AENGMTFSRLLNYKYSDTLKKMDPDHLVALVTEVIPNYSCLVFCPSKKNCENVAEMICKF
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 LSKEYLKHKEKEKCEVIKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYS
::: .
XP_011 LSKSFS
>>XP_016863171 (OMIM: 606769) PREDICTED: helicase POLQ-l (604 aa)
initn: 3743 init1: 3743 opt: 3749 Z-score: 4138.9 bits: 776.7 E(85289): 0
Smith-Waterman score: 3749; 99.5% identity (99.7% similar) in 585 aa overlap (518-1101:20-604)
490 500 510 520 530 540
pF1KE2 SKTTQIIGMSATLNNVEDLQKFLQAEYYTSQFRP-VELKEYLKINDTIYEVDSKAENGMT
:. : :::::::::::::::::::::::::
XP_016 MLKTYKSFFKQNIIPVNLDQYVPKVELKEYLKINDTIYEVDSKAENGMT
10 20 30 40
550 560 570 580 590 600
pF1KE2 FSRLLNYKYSDTLKKMDPDHLVALVTEVIPNYSCLVFCPSKKNCENVAEMICKFLSKEYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSRLLNYKYSDTLKKMDPDHLVALVTEVIPNYSCLVFCPSKKNCENVAEMICKFLSKEYL
50 60 70 80 90 100
610 620 630 640 650 660
pF1KE2 KHKEKEKCEVIKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYSTGVLCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KHKEKEKCEVIKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYSTGVLCL
110 120 130 140 150 160
670 680 690 700 710 720
pF1KE2 FTCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDTIGESILILQEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDTIGESILILQEK
170 180 190 200 210 220
730 740 750 760 770 780
pF1KE2 DKQQVLELITKPLENCYSHLVQEFTKGIQTLFLSLIGLKIATNLDDIYHFMNGTFFGVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKQQVLELITKPLENCYSHLVQEFTKGIQTLFLSLIGLKIATNLDDIYHFMNGTFFGVQQ
230 240 250 260 270 280
790 800 810 820 830 840
pF1KE2 KVLLKEKSLWEITVESLRYLTEKGLLQKDTIYKSEEEVQYNFHITKLGRASFKGTIDLAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVLLKEKSLWEITVESLRYLTEKGLLQKDTIYKSEEEVQYNFHITKLGRASFKGTIDLAY
290 300 310 320 330 340
850 860 870 880 890 900
pF1KE2 CDILYRDLKKGLEGLVLESLLHLIYLTTPYDLVSQCNPDWMIYFRQFSQLSPAEQNVAAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CDILYRDLKKGLEGLVLESLLHLIYLTTPYDLVSQCNPDWMIYFRQFSQLSPAEQNVAAI
350 360 370 380 390 400
910 920 930 940 950 960
pF1KE2 LGVSESFIGKKASGQAIGKKVDKNVVNRLYLSFVLYTLLKETNIWTVSEKFNMPRGYIQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGVSESFIGKKASGQAIGKKVDKNVVNRLYLSFVLYTLLKETNIWTVSEKFNMPRGYIQN
410 420 430 440 450 460
970 980 990 1000 1010 1020
pF1KE2 LLTGTASFSSCVLHFCEELEEFWVYRALLVELTKKLTYCVKAELIPLMEVTGVLEGRAKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLTGTASFSSCVLHFCEELEEFWVYRALLVELTKKLTYCVKAELIPLMEVTGVLEGRAKQ
470 480 490 500 510 520
1030 1040 1050 1060 1070 1080
pF1KE2 LYSAGYKSLMHLANANPEVLVRTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEVEELLRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYSAGYKSLMHLANANPEVLVRTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEVEELLRL
530 540 550 560 570 580
1090 1100
pF1KE2 PSDFPGAVASSTDKA
:::::::::::::::
XP_016 PSDFPGAVASSTDKA
590 600
1101 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 17:24:26 2016 done: Sun Nov 6 17:24:27 2016
Total Scan time: 9.560 Total Display time: 0.260
Function used was FASTA [36.3.4 Apr, 2011]