Result of FASTA (omim) for
pFN21AE2313
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2313, 625 aa
1>>>pF1KE2313 625 - 625 aa - 625 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.3375+/-0.000418; mu= 14.3556+/- 0.026
mean_var=84.2081+/-16.719, 0's: 0 Z-trim(112.3): 44 B-trim: 0 in 0/54
Lambda= 0.139765
statistics sampled from 21154 (21182) to 21154 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.613), E-opt: 0.2 (0.248), width: 16
Scan time: 11.310
The best scores are: opt bits E(85289)
XP_005252270 (OMIM: 610404) PREDICTED: recQ-mediat ( 625) 4079 832.8 0
XP_011517336 (OMIM: 610404) PREDICTED: recQ-mediat ( 625) 4079 832.8 0
XP_005252268 (OMIM: 610404) PREDICTED: recQ-mediat ( 625) 4079 832.8 0
XP_016870629 (OMIM: 610404) PREDICTED: recQ-mediat ( 625) 4079 832.8 0
NP_079221 (OMIM: 610404) recQ-mediated genome inst ( 625) 4079 832.8 0
XP_016876266 (OMIM: 614392) PREDICTED: tudor domai ( 744) 198 50.2 3e-05
NP_001139542 (OMIM: 614392) tudor domain-containin ( 744) 198 50.2 3e-05
XP_005266613 (OMIM: 614392) PREDICTED: tudor domai ( 809) 198 50.3 3.2e-05
XP_011533551 (OMIM: 614392) PREDICTED: tudor domai ( 341) 184 47.3 0.00011
NP_001139543 (OMIM: 614392) tudor domain-containin ( 651) 184 47.4 0.00019
NP_110421 (OMIM: 614392) tudor domain-containing p ( 651) 184 47.4 0.00019
XP_011533549 (OMIM: 614392) PREDICTED: tudor domai ( 715) 184 47.4 0.0002
XP_005266617 (OMIM: 614392) PREDICTED: tudor domai ( 716) 184 47.4 0.0002
>>XP_005252270 (OMIM: 610404) PREDICTED: recQ-mediated g (625 aa)
initn: 4079 init1: 4079 opt: 4079 Z-score: 4445.8 bits: 832.8 E(85289): 0
Smith-Waterman score: 4079; 99.8% identity (100.0% similar) in 625 aa overlap (1-625:1-625)
10 20 30 40 50 60
pF1KE2 MNVTSIALRAETWLLAAWHVKVPPMWLEACINWIQEENNNVNLSQAQMNKQVFEQWLLTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MNVTSIALRAETWLLAAWHVKVPPMWLEACINWIQEENNNVNLSQAQMNKQVFEQWLLTD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LRDLEHPLLPDGILEIPKGELNGFYALQINSLVDVSQPAYSQIQKLRGKNTTNDLVTAEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRDLEHPLLPDGILEIPKGELNGFYALQINSLVDVSQPAYSQIQKLRGKNTTNDLVTAEA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 QVTPKPWEAKPSRMLMLQLTDGIVQIQGMEYQPIPILHSDLPPGTKILIYGNISFRLGVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QVTPKPWEAKPSRMLMLQLTDGIVQIQGMEYQPIPILHSDLPPGTKILIYGNISFRLGVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 LLKPENVKVLGGEVDALLEEYAQEKVLARLIGEPDLVVSVIPNNSNENIPRVTDVLDPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLKPENVKVLGGEVDALLEEYAQEKVLARLIGEPDLVVSVIPNNSNENIPRVTDVLDPAL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GPSDEELLASLDENDELTANNDTSSERCFTTGSSSNTIPTRQSSFEPEFVISPRPKEEPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPSDEELLASLDENDELTANNDTSSERCFTTGSSSNTIPTRQSSFEPEFVISPRPKEEPS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 NLSIHVMDGELDDFSLEEALLLEETVQKEQMETKELQPLTFNRNADRSIERFSHNPNTTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NLSIHVMDGELDDFSLEEALLLEETVQKEQMETKELQPLTFNRNADRSIERFSHNPNTTN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 NFSLTCKNGNNNWSEKNVSEQMTNEDKSFGCPSVRDQNRSIFSVHCNVPLAHDFTNKEKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NFSLTCKNGNNNWSEKNVSEQMTNEDKSFGCPSVRDQNRSIFSVHCNVPLAHDFTNKEKN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 LETDNKIKQTSSSDSHSLNNKILNREVVNYVQKRSSQISNENDCNLQSCSLRSSENSINL
::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::
XP_005 LETDNKIKQTSSSDSHSLNNKILNREVVNYVQKRNSQISNENDCNLQSCSLRSSENSINL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 SIAMDLYSPPFVYLSVLMASKPKEVTTVKVKAFIVTLTGNLSSSGGIWSITAKVSDGTAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SIAMDLYSPPFVYLSVLMASKPKEVTTVKVKAFIVTLTGNLSSSGGIWSITAKVSDGTAY
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 LDVDFVDEILTSLIGFSVPEMKQSKKDPLQYQKFLEGLQKCQRDLIDLCCLMTISFNPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDVDFVDEILTSLIGFSVPEMKQSKKDPLQYQKFLEGLQKCQRDLIDLCCLMTISFNPSL
550 560 570 580 590 600
610 620
pF1KE2 SKAMVLALQDVNMEHLENLKKRLNK
:::::::::::::::::::::::::
XP_005 SKAMVLALQDVNMEHLENLKKRLNK
610 620
>>XP_011517336 (OMIM: 610404) PREDICTED: recQ-mediated g (625 aa)
initn: 4079 init1: 4079 opt: 4079 Z-score: 4445.8 bits: 832.8 E(85289): 0
Smith-Waterman score: 4079; 99.8% identity (100.0% similar) in 625 aa overlap (1-625:1-625)
10 20 30 40 50 60
pF1KE2 MNVTSIALRAETWLLAAWHVKVPPMWLEACINWIQEENNNVNLSQAQMNKQVFEQWLLTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNVTSIALRAETWLLAAWHVKVPPMWLEACINWIQEENNNVNLSQAQMNKQVFEQWLLTD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LRDLEHPLLPDGILEIPKGELNGFYALQINSLVDVSQPAYSQIQKLRGKNTTNDLVTAEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRDLEHPLLPDGILEIPKGELNGFYALQINSLVDVSQPAYSQIQKLRGKNTTNDLVTAEA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 QVTPKPWEAKPSRMLMLQLTDGIVQIQGMEYQPIPILHSDLPPGTKILIYGNISFRLGVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVTPKPWEAKPSRMLMLQLTDGIVQIQGMEYQPIPILHSDLPPGTKILIYGNISFRLGVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 LLKPENVKVLGGEVDALLEEYAQEKVLARLIGEPDLVVSVIPNNSNENIPRVTDVLDPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLKPENVKVLGGEVDALLEEYAQEKVLARLIGEPDLVVSVIPNNSNENIPRVTDVLDPAL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GPSDEELLASLDENDELTANNDTSSERCFTTGSSSNTIPTRQSSFEPEFVISPRPKEEPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPSDEELLASLDENDELTANNDTSSERCFTTGSSSNTIPTRQSSFEPEFVISPRPKEEPS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 NLSIHVMDGELDDFSLEEALLLEETVQKEQMETKELQPLTFNRNADRSIERFSHNPNTTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLSIHVMDGELDDFSLEEALLLEETVQKEQMETKELQPLTFNRNADRSIERFSHNPNTTN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 NFSLTCKNGNNNWSEKNVSEQMTNEDKSFGCPSVRDQNRSIFSVHCNVPLAHDFTNKEKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NFSLTCKNGNNNWSEKNVSEQMTNEDKSFGCPSVRDQNRSIFSVHCNVPLAHDFTNKEKN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 LETDNKIKQTSSSDSHSLNNKILNREVVNYVQKRSSQISNENDCNLQSCSLRSSENSINL
::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::
XP_011 LETDNKIKQTSSSDSHSLNNKILNREVVNYVQKRNSQISNENDCNLQSCSLRSSENSINL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 SIAMDLYSPPFVYLSVLMASKPKEVTTVKVKAFIVTLTGNLSSSGGIWSITAKVSDGTAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIAMDLYSPPFVYLSVLMASKPKEVTTVKVKAFIVTLTGNLSSSGGIWSITAKVSDGTAY
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 LDVDFVDEILTSLIGFSVPEMKQSKKDPLQYQKFLEGLQKCQRDLIDLCCLMTISFNPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDVDFVDEILTSLIGFSVPEMKQSKKDPLQYQKFLEGLQKCQRDLIDLCCLMTISFNPSL
550 560 570 580 590 600
610 620
pF1KE2 SKAMVLALQDVNMEHLENLKKRLNK
:::::::::::::::::::::::::
XP_011 SKAMVLALQDVNMEHLENLKKRLNK
610 620
>>XP_005252268 (OMIM: 610404) PREDICTED: recQ-mediated g (625 aa)
initn: 4079 init1: 4079 opt: 4079 Z-score: 4445.8 bits: 832.8 E(85289): 0
Smith-Waterman score: 4079; 99.8% identity (100.0% similar) in 625 aa overlap (1-625:1-625)
10 20 30 40 50 60
pF1KE2 MNVTSIALRAETWLLAAWHVKVPPMWLEACINWIQEENNNVNLSQAQMNKQVFEQWLLTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MNVTSIALRAETWLLAAWHVKVPPMWLEACINWIQEENNNVNLSQAQMNKQVFEQWLLTD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LRDLEHPLLPDGILEIPKGELNGFYALQINSLVDVSQPAYSQIQKLRGKNTTNDLVTAEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRDLEHPLLPDGILEIPKGELNGFYALQINSLVDVSQPAYSQIQKLRGKNTTNDLVTAEA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 QVTPKPWEAKPSRMLMLQLTDGIVQIQGMEYQPIPILHSDLPPGTKILIYGNISFRLGVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QVTPKPWEAKPSRMLMLQLTDGIVQIQGMEYQPIPILHSDLPPGTKILIYGNISFRLGVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 LLKPENVKVLGGEVDALLEEYAQEKVLARLIGEPDLVVSVIPNNSNENIPRVTDVLDPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLKPENVKVLGGEVDALLEEYAQEKVLARLIGEPDLVVSVIPNNSNENIPRVTDVLDPAL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GPSDEELLASLDENDELTANNDTSSERCFTTGSSSNTIPTRQSSFEPEFVISPRPKEEPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPSDEELLASLDENDELTANNDTSSERCFTTGSSSNTIPTRQSSFEPEFVISPRPKEEPS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 NLSIHVMDGELDDFSLEEALLLEETVQKEQMETKELQPLTFNRNADRSIERFSHNPNTTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NLSIHVMDGELDDFSLEEALLLEETVQKEQMETKELQPLTFNRNADRSIERFSHNPNTTN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 NFSLTCKNGNNNWSEKNVSEQMTNEDKSFGCPSVRDQNRSIFSVHCNVPLAHDFTNKEKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NFSLTCKNGNNNWSEKNVSEQMTNEDKSFGCPSVRDQNRSIFSVHCNVPLAHDFTNKEKN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 LETDNKIKQTSSSDSHSLNNKILNREVVNYVQKRSSQISNENDCNLQSCSLRSSENSINL
::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::
XP_005 LETDNKIKQTSSSDSHSLNNKILNREVVNYVQKRNSQISNENDCNLQSCSLRSSENSINL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 SIAMDLYSPPFVYLSVLMASKPKEVTTVKVKAFIVTLTGNLSSSGGIWSITAKVSDGTAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SIAMDLYSPPFVYLSVLMASKPKEVTTVKVKAFIVTLTGNLSSSGGIWSITAKVSDGTAY
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 LDVDFVDEILTSLIGFSVPEMKQSKKDPLQYQKFLEGLQKCQRDLIDLCCLMTISFNPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDVDFVDEILTSLIGFSVPEMKQSKKDPLQYQKFLEGLQKCQRDLIDLCCLMTISFNPSL
550 560 570 580 590 600
610 620
pF1KE2 SKAMVLALQDVNMEHLENLKKRLNK
:::::::::::::::::::::::::
XP_005 SKAMVLALQDVNMEHLENLKKRLNK
610 620
>>XP_016870629 (OMIM: 610404) PREDICTED: recQ-mediated g (625 aa)
initn: 4079 init1: 4079 opt: 4079 Z-score: 4445.8 bits: 832.8 E(85289): 0
Smith-Waterman score: 4079; 99.8% identity (100.0% similar) in 625 aa overlap (1-625:1-625)
10 20 30 40 50 60
pF1KE2 MNVTSIALRAETWLLAAWHVKVPPMWLEACINWIQEENNNVNLSQAQMNKQVFEQWLLTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNVTSIALRAETWLLAAWHVKVPPMWLEACINWIQEENNNVNLSQAQMNKQVFEQWLLTD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LRDLEHPLLPDGILEIPKGELNGFYALQINSLVDVSQPAYSQIQKLRGKNTTNDLVTAEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRDLEHPLLPDGILEIPKGELNGFYALQINSLVDVSQPAYSQIQKLRGKNTTNDLVTAEA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 QVTPKPWEAKPSRMLMLQLTDGIVQIQGMEYQPIPILHSDLPPGTKILIYGNISFRLGVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVTPKPWEAKPSRMLMLQLTDGIVQIQGMEYQPIPILHSDLPPGTKILIYGNISFRLGVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 LLKPENVKVLGGEVDALLEEYAQEKVLARLIGEPDLVVSVIPNNSNENIPRVTDVLDPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLKPENVKVLGGEVDALLEEYAQEKVLARLIGEPDLVVSVIPNNSNENIPRVTDVLDPAL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GPSDEELLASLDENDELTANNDTSSERCFTTGSSSNTIPTRQSSFEPEFVISPRPKEEPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPSDEELLASLDENDELTANNDTSSERCFTTGSSSNTIPTRQSSFEPEFVISPRPKEEPS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 NLSIHVMDGELDDFSLEEALLLEETVQKEQMETKELQPLTFNRNADRSIERFSHNPNTTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLSIHVMDGELDDFSLEEALLLEETVQKEQMETKELQPLTFNRNADRSIERFSHNPNTTN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 NFSLTCKNGNNNWSEKNVSEQMTNEDKSFGCPSVRDQNRSIFSVHCNVPLAHDFTNKEKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFSLTCKNGNNNWSEKNVSEQMTNEDKSFGCPSVRDQNRSIFSVHCNVPLAHDFTNKEKN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 LETDNKIKQTSSSDSHSLNNKILNREVVNYVQKRSSQISNENDCNLQSCSLRSSENSINL
::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::
XP_016 LETDNKIKQTSSSDSHSLNNKILNREVVNYVQKRNSQISNENDCNLQSCSLRSSENSINL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 SIAMDLYSPPFVYLSVLMASKPKEVTTVKVKAFIVTLTGNLSSSGGIWSITAKVSDGTAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIAMDLYSPPFVYLSVLMASKPKEVTTVKVKAFIVTLTGNLSSSGGIWSITAKVSDGTAY
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 LDVDFVDEILTSLIGFSVPEMKQSKKDPLQYQKFLEGLQKCQRDLIDLCCLMTISFNPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDVDFVDEILTSLIGFSVPEMKQSKKDPLQYQKFLEGLQKCQRDLIDLCCLMTISFNPSL
550 560 570 580 590 600
610 620
pF1KE2 SKAMVLALQDVNMEHLENLKKRLNK
:::::::::::::::::::::::::
XP_016 SKAMVLALQDVNMEHLENLKKRLNK
610 620
>>NP_079221 (OMIM: 610404) recQ-mediated genome instabil (625 aa)
initn: 4079 init1: 4079 opt: 4079 Z-score: 4445.8 bits: 832.8 E(85289): 0
Smith-Waterman score: 4079; 99.8% identity (100.0% similar) in 625 aa overlap (1-625:1-625)
10 20 30 40 50 60
pF1KE2 MNVTSIALRAETWLLAAWHVKVPPMWLEACINWIQEENNNVNLSQAQMNKQVFEQWLLTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 MNVTSIALRAETWLLAAWHVKVPPMWLEACINWIQEENNNVNLSQAQMNKQVFEQWLLTD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LRDLEHPLLPDGILEIPKGELNGFYALQINSLVDVSQPAYSQIQKLRGKNTTNDLVTAEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 LRDLEHPLLPDGILEIPKGELNGFYALQINSLVDVSQPAYSQIQKLRGKNTTNDLVTAEA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 QVTPKPWEAKPSRMLMLQLTDGIVQIQGMEYQPIPILHSDLPPGTKILIYGNISFRLGVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 QVTPKPWEAKPSRMLMLQLTDGIVQIQGMEYQPIPILHSDLPPGTKILIYGNISFRLGVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 LLKPENVKVLGGEVDALLEEYAQEKVLARLIGEPDLVVSVIPNNSNENIPRVTDVLDPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 LLKPENVKVLGGEVDALLEEYAQEKVLARLIGEPDLVVSVIPNNSNENIPRVTDVLDPAL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GPSDEELLASLDENDELTANNDTSSERCFTTGSSSNTIPTRQSSFEPEFVISPRPKEEPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 GPSDEELLASLDENDELTANNDTSSERCFTTGSSSNTIPTRQSSFEPEFVISPRPKEEPS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 NLSIHVMDGELDDFSLEEALLLEETVQKEQMETKELQPLTFNRNADRSIERFSHNPNTTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 NLSIHVMDGELDDFSLEEALLLEETVQKEQMETKELQPLTFNRNADRSIERFSHNPNTTN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 NFSLTCKNGNNNWSEKNVSEQMTNEDKSFGCPSVRDQNRSIFSVHCNVPLAHDFTNKEKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 NFSLTCKNGNNNWSEKNVSEQMTNEDKSFGCPSVRDQNRSIFSVHCNVPLAHDFTNKEKN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 LETDNKIKQTSSSDSHSLNNKILNREVVNYVQKRSSQISNENDCNLQSCSLRSSENSINL
::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::
NP_079 LETDNKIKQTSSSDSHSLNNKILNREVVNYVQKRNSQISNENDCNLQSCSLRSSENSINL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 SIAMDLYSPPFVYLSVLMASKPKEVTTVKVKAFIVTLTGNLSSSGGIWSITAKVSDGTAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 SIAMDLYSPPFVYLSVLMASKPKEVTTVKVKAFIVTLTGNLSSSGGIWSITAKVSDGTAY
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 LDVDFVDEILTSLIGFSVPEMKQSKKDPLQYQKFLEGLQKCQRDLIDLCCLMTISFNPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 LDVDFVDEILTSLIGFSVPEMKQSKKDPLQYQKFLEGLQKCQRDLIDLCCLMTISFNPSL
550 560 570 580 590 600
610 620
pF1KE2 SKAMVLALQDVNMEHLENLKKRLNK
:::::::::::::::::::::::::
NP_079 SKAMVLALQDVNMEHLENLKKRLNK
610 620
>>XP_016876266 (OMIM: 614392) PREDICTED: tudor domain-co (744 aa)
initn: 243 init1: 191 opt: 198 Z-score: 215.3 bits: 50.2 E(85289): 3e-05
Smith-Waterman score: 220; 28.9% identity (58.2% similar) in 194 aa overlap (16-209:12-169)
10 20 30 40 50 60
pF1KE2 MNVTSIALRAETWLLAAWHVKVPPMWLEACINWIQEENNNVNLSQAQMNKQVFEQWLLTD
:.:... .::: . . .. ::: ... : ::
XP_016 MAQVAGAALSQAGWYLS--DEGIEACTS--SPDKVNVN--------DIILIALNTD
10 20 30 40
70 80 90 100 110 120
pF1KE2 LRDLEHPLLPDGILEIPKGELNGFYALQINSLVDVSQPAYSQIQKLRGKNTTNDLVTAEA
:: . . .::. .: .:... . . : ::::.:. . .: . :.
XP_016 LRTIGKKFLPS---DINSGKVEKLEG-----------PCVLQIQKIRNVAAPKD--NEES
50 60 70 80
130 140 150 160 170 180
pF1KE2 QVTPKPWEAKPSRMLMLQLTDGIVQIQGMEYQPIPILHSDLPPGTKILIYGNISFRLGVL
:..: ::: ::.::: .. ..:.. . . . :::::. . : .... : :
XP_016 QAAP--------RMLRLQMTDGHISCTAVEFSYMSKISLNTPPGTKVKLSGIVDIKNGFL
90 100 110 120 130 140
190 200 210 220 230 240
pF1KE2 LLKPENVKVLGGEVDALLEEYAQEKVLARLIGEPDLVVSVIPNNSNENIPRVTDVLDPAL
::. :. ::::::. :.:.. .. :..
XP_016 LLNDSNTTVLGGEVEHLIEKWELQRSLSKHNRSNIGTEGGPPPFVPFGQKCVSHVQVDSR
150 160 170 180 190 200
>>NP_001139542 (OMIM: 614392) tudor domain-containing pr (744 aa)
initn: 243 init1: 191 opt: 198 Z-score: 215.3 bits: 50.2 E(85289): 3e-05
Smith-Waterman score: 220; 28.9% identity (58.2% similar) in 194 aa overlap (16-209:12-169)
10 20 30 40 50 60
pF1KE2 MNVTSIALRAETWLLAAWHVKVPPMWLEACINWIQEENNNVNLSQAQMNKQVFEQWLLTD
:.:... .::: . . .. ::: ... : ::
NP_001 MAQVAGAALSQAGWYLS--DEGIEACTS--SPDKVNVN--------DIILIALNTD
10 20 30 40
70 80 90 100 110 120
pF1KE2 LRDLEHPLLPDGILEIPKGELNGFYALQINSLVDVSQPAYSQIQKLRGKNTTNDLVTAEA
:: . . .::. .: .:... . . : ::::.:. . .: . :.
NP_001 LRTIGKKFLPS---DINSGKVEKLEG-----------PCVLQIQKIRNVAAPKD--NEES
50 60 70 80
130 140 150 160 170 180
pF1KE2 QVTPKPWEAKPSRMLMLQLTDGIVQIQGMEYQPIPILHSDLPPGTKILIYGNISFRLGVL
:..: ::: ::.::: .. ..:.. . . . :::::. . : .... : :
NP_001 QAAP--------RMLRLQMTDGHISCTAVEFSYMSKISLNTPPGTKVKLSGIVDIKNGFL
90 100 110 120 130 140
190 200 210 220 230 240
pF1KE2 LLKPENVKVLGGEVDALLEEYAQEKVLARLIGEPDLVVSVIPNNSNENIPRVTDVLDPAL
::. :. ::::::. :.:.. .. :..
NP_001 LLNDSNTTVLGGEVEHLIEKWELQRSLSKHNRSNIGTEGGPPPFVPFGQKCVSHVQVDSR
150 160 170 180 190 200
>>XP_005266613 (OMIM: 614392) PREDICTED: tudor domain-co (809 aa)
initn: 270 init1: 191 opt: 198 Z-score: 214.7 bits: 50.3 E(85289): 3.2e-05
Smith-Waterman score: 220; 28.9% identity (58.2% similar) in 194 aa overlap (16-209:12-169)
10 20 30 40 50 60
pF1KE2 MNVTSIALRAETWLLAAWHVKVPPMWLEACINWIQEENNNVNLSQAQMNKQVFEQWLLTD
:.:... .::: . . .. ::: ... : ::
XP_005 MAQVAGAALSQAGWYLS--DEGIEACTS--SPDKVNVN--------DIILIALNTD
10 20 30 40
70 80 90 100 110 120
pF1KE2 LRDLEHPLLPDGILEIPKGELNGFYALQINSLVDVSQPAYSQIQKLRGKNTTNDLVTAEA
:: . . .::. .: .:... . . : ::::.:. . .: . :.
XP_005 LRTIGKKFLPS---DINSGKVEKLEG-----------PCVLQIQKIRNVAAPKD--NEES
50 60 70 80
130 140 150 160 170 180
pF1KE2 QVTPKPWEAKPSRMLMLQLTDGIVQIQGMEYQPIPILHSDLPPGTKILIYGNISFRLGVL
:..: ::: ::.::: .. ..:.. . . . :::::. . : .... : :
XP_005 QAAP--------RMLRLQMTDGHISCTAVEFSYMSKISLNTPPGTKVKLSGIVDIKNGFL
90 100 110 120 130 140
190 200 210 220 230 240
pF1KE2 LLKPENVKVLGGEVDALLEEYAQEKVLARLIGEPDLVVSVIPNNSNENIPRVTDVLDPAL
::. :. ::::::. :.:.. .. :..
XP_005 LLNDSNTTVLGGEVEHLIEKWELQRSLSKHNRSNIGTEGGPPPFVPFGQKCVSHVQVDSR
150 160 170 180 190 200
>>XP_011533551 (OMIM: 614392) PREDICTED: tudor domain-co (341 aa)
initn: 184 init1: 184 opt: 184 Z-score: 205.5 bits: 47.3 E(85289): 0.00011
Smith-Waterman score: 184; 36.8% identity (71.1% similar) in 76 aa overlap (134-209:1-76)
110 120 130 140 150 160
pF1KE2 QKLRGKNTTNDLVTAEAQVTPKPWEAKPSRMLMLQLTDGIVQIQGMEYQPIPILHSDLPP
:: ::.::: .. ..:.. . . . ::
XP_011 MLRLQMTDGHISCTAVEFSYMSKISLNTPP
10 20 30
170 180 190 200 210 220
pF1KE2 GTKILIYGNISFRLGVLLLKPENVKVLGGEVDALLEEYAQEKVLARLIGEPDLVVSVIPN
:::. . : .... : :::. :. ::::::. :.:.. .. :..
XP_011 GTKVKLSGIVDIKNGFLLLNDSNTTVLGGEVEHLIEKWELQRSLSKHNRSNIGTEGGPPP
40 50 60 70 80 90
230 240 250 260 270 280
pF1KE2 NSNENIPRVTDVLDPALGPSDEELLASLDENDELTANNDTSSERCFTTGSSSNTIPTRQS
XP_011 FVPFGQKCVSHVQVDSRELDRRKTLQVTMPVKPTNDNDEFEKQRTAAIAEVAKSKETKTF
100 110 120 130 140 150
>>NP_001139543 (OMIM: 614392) tudor domain-containing pr (651 aa)
initn: 184 init1: 184 opt: 184 Z-score: 201.0 bits: 47.4 E(85289): 0.00019
Smith-Waterman score: 184; 36.8% identity (71.1% similar) in 76 aa overlap (134-209:1-76)
110 120 130 140 150 160
pF1KE2 QKLRGKNTTNDLVTAEAQVTPKPWEAKPSRMLMLQLTDGIVQIQGMEYQPIPILHSDLPP
:: ::.::: .. ..:.. . . . ::
NP_001 MLRLQMTDGHISCTAVEFSYMSKISLNTPP
10 20 30
170 180 190 200 210 220
pF1KE2 GTKILIYGNISFRLGVLLLKPENVKVLGGEVDALLEEYAQEKVLARLIGEPDLVVSVIPN
:::. . : .... : :::. :. ::::::. :.:.. .. :..
NP_001 GTKVKLSGIVDIKNGFLLLNDSNTTVLGGEVEHLIEKWELQRSLSKHNRSNIGTEGGPPP
40 50 60 70 80 90
230 240 250 260 270 280
pF1KE2 NSNENIPRVTDVLDPALGPSDEELLASLDENDELTANNDTSSERCFTTGSSSNTIPTRQS
NP_001 FVPFGQKCVSHVQVDSRELDRRKTLQVTMPVKPTNDNDEFEKQRTAAIAEVAKSKETKTF
100 110 120 130 140 150
625 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 15:45:41 2016 done: Sun Nov 6 15:45:42 2016
Total Scan time: 11.310 Total Display time: 0.100
Function used was FASTA [36.3.4 Apr, 2011]