Result of FASTA (omim) for
pFN21AE2290
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2290, 358 aa
1>>>pF1KE2290 358 - 358 aa - 358 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.5312+/-0.000353; mu= 21.0588+/- 0.022
mean_var=83.3664+/-19.076, 0's: 0 Z-trim(115.1): 194 B-trim: 1530 in 1/54
Lambda= 0.140468
statistics sampled from 25120 (25385) to 25120 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.671), E-opt: 0.2 (0.298), width: 16
Scan time: 8.530
The best scores are: opt bits E(85289)
NP_000947 (OMIM: 176804,208550) prostaglandin E2 r ( 358) 2367 489.6 4.6e-138
NP_000951 (OMIM: 600022) prostacyclin receptor [Ho ( 386) 787 169.4 1.2e-41
NP_000944 (OMIM: 604687,607277) prostaglandin D2 r ( 359) 773 166.5 8.1e-41
XP_005267948 (OMIM: 604687,607277) PREDICTED: pros ( 359) 773 166.5 8.1e-41
NP_001268398 (OMIM: 604687,607277) prostaglandin D ( 296) 759 163.6 5.1e-40
XP_005259150 (OMIM: 600022) PREDICTED: prostacycli ( 342) 663 144.2 4e-34
XP_005259152 (OMIM: 600022) PREDICTED: prostacycli ( 257) 661 143.7 4.5e-34
XP_016865148 (OMIM: 601586) PREDICTED: prostagland ( 313) 403 91.5 2.8e-18
XP_016865147 (OMIM: 601586) PREDICTED: prostagland ( 325) 403 91.5 2.8e-18
XP_016865146 (OMIM: 601586) PREDICTED: prostagland ( 326) 403 91.5 2.8e-18
XP_016865145 (OMIM: 601586) PREDICTED: prostagland ( 350) 403 91.5 3e-18
NP_000949 (OMIM: 601586) prostaglandin E2 receptor ( 488) 403 91.7 3.7e-18
NP_001119516 (OMIM: 176806) prostaglandin E2 recep ( 390) 380 86.9 8.1e-17
NP_942012 (OMIM: 176806) prostaglandin E2 receptor ( 390) 380 86.9 8.1e-17
NP_942007 (OMIM: 176806) prostaglandin E2 receptor ( 390) 380 86.9 8.1e-17
XP_011540112 (OMIM: 176806) PREDICTED: prostagland ( 410) 380 87.0 8.3e-17
NP_942011 (OMIM: 176806) prostaglandin E2 receptor ( 418) 379 86.8 9.7e-17
NP_942008 (OMIM: 176806) prostaglandin E2 receptor ( 388) 373 85.5 2.1e-16
XP_011526516 (OMIM: 188070,614009) PREDICTED: thro ( 343) 371 85.0 2.6e-16
NP_001051 (OMIM: 188070,614009) thromboxane A2 rec ( 343) 371 85.0 2.6e-16
NP_963998 (OMIM: 188070,614009) thromboxane A2 rec ( 407) 366 84.1 5.9e-16
NP_942009 (OMIM: 176806) prostaglandin E2 receptor ( 374) 365 83.9 6.4e-16
NP_942010 (OMIM: 176806) prostaglandin E2 receptor ( 365) 364 83.7 7.3e-16
NP_000946 (OMIM: 176802) prostaglandin E2 receptor ( 402) 329 76.6 1.1e-13
XP_006724891 (OMIM: 300538,300539,304800) PREDICTE ( 371) 291 68.9 2.1e-11
NP_000045 (OMIM: 300538,300539,304800) vasopressin ( 371) 291 68.9 2.1e-11
XP_016857362 (OMIM: 600563) PREDICTED: prostagland ( 291) 260 62.5 1.4e-09
NP_001034674 (OMIM: 600563) prostaglandin F2-alpha ( 297) 260 62.5 1.4e-09
NP_000950 (OMIM: 600563) prostaglandin F2-alpha re ( 359) 260 62.6 1.6e-09
XP_005245114 (OMIM: 612250) PREDICTED: G-protein c ( 529) 212 53.0 1.7e-06
XP_016856350 (OMIM: 612250) PREDICTED: G-protein c ( 529) 212 53.0 1.7e-06
XP_016856351 (OMIM: 612250) PREDICTED: G-protein c ( 529) 212 53.0 1.7e-06
XP_011507678 (OMIM: 612250) PREDICTED: G-protein c ( 529) 212 53.0 1.7e-06
XP_011507677 (OMIM: 612250) PREDICTED: G-protein c ( 529) 212 53.0 1.7e-06
NP_722561 (OMIM: 612250) G-protein coupled recepto ( 529) 212 53.0 1.7e-06
XP_016856349 (OMIM: 612250) PREDICTED: G-protein c ( 529) 212 53.0 1.7e-06
XP_011507679 (OMIM: 612250) PREDICTED: G-protein c ( 529) 212 53.0 1.7e-06
XP_005245113 (OMIM: 612250) PREDICTED: G-protein c ( 529) 212 53.0 1.7e-06
NP_001254539 (OMIM: 612250) G-protein coupled rece ( 529) 212 53.0 1.7e-06
XP_011507680 (OMIM: 612250) PREDICTED: G-protein c ( 529) 212 53.0 1.7e-06
NP_001254540 (OMIM: 612250) G-protein coupled rece ( 546) 212 53.1 1.8e-06
XP_016856348 (OMIM: 612250) PREDICTED: G-protein c ( 549) 212 53.1 1.8e-06
XP_005245112 (OMIM: 612250) PREDICTED: G-protein c ( 549) 212 53.1 1.8e-06
NP_001254538 (OMIM: 612250) G-protein coupled rece ( 549) 212 53.1 1.8e-06
XP_006711314 (OMIM: 612250) PREDICTED: G-protein c ( 552) 212 53.1 1.8e-06
XP_011507673 (OMIM: 612250) PREDICTED: G-protein c ( 552) 212 53.1 1.8e-06
XP_011507674 (OMIM: 612250) PREDICTED: G-protein c ( 552) 212 53.1 1.8e-06
XP_011507675 (OMIM: 612250) PREDICTED: G-protein c ( 552) 212 53.1 1.8e-06
XP_011507672 (OMIM: 612250) PREDICTED: G-protein c ( 552) 212 53.1 1.8e-06
XP_016856347 (OMIM: 612250) PREDICTED: G-protein c ( 552) 212 53.1 1.8e-06
>>NP_000947 (OMIM: 176804,208550) prostaglandin E2 recep (358 aa)
initn: 2367 init1: 2367 opt: 2367 Z-score: 2599.6 bits: 489.6 E(85289): 4.6e-138
Smith-Waterman score: 2367; 100.0% identity (100.0% similar) in 358 aa overlap (1-358:1-358)
10 20 30 40 50 60
pF1KE2 MGNASNDSQSEDCETRQWLPPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MGNASNDSQSEDCETRQWLPPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 RSSLSLFHVLVTELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RSSLSLFHVLVTELVFTDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 LATMLMLFAMALERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LATMLMLFAMALERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 YCPGTWCFIRHGRTAYLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YCPGTWCFIRHGRTAYLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIFAYMNETSSRKEKWDLQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIFAYMNETSSRKEKWDLQA
250 260 270 280 290 300
310 320 330 340 350
pF1KE2 LRFLSINSIIDPWVFAILRPPVLRLMRSVLCCRISLRTQDATQTSCSTQSDASKQADL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LRFLSINSIIDPWVFAILRPPVLRLMRSVLCCRISLRTQDATQTSCSTQSDASKQADL
310 320 330 340 350
>>NP_000951 (OMIM: 600022) prostacyclin receptor [Homo s (386 aa)
initn: 783 init1: 346 opt: 787 Z-score: 868.8 bits: 169.4 E(85289): 1.2e-41
Smith-Waterman score: 848; 46.1% identity (69.6% similar) in 332 aa overlap (10-332:2-309)
10 20 30 40 50 60
pF1KE2 MGNASNDSQSEDCETRQWLPPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGR
...:.. .. . .:: :..:: :::.:: .::..: :: :
NP_000 MADSCRNLTYVRGSVGPATSTLMFVAGVVGNGLALGIL----------SARR
10 20 30 40
70 80 90 100 110
pF1KE2 RSSLSLFHVLVTELVFTDLLGTCLISPVVLASYARNQTLVALAPESRA-CTYFAFAMTFF
. : : :::: :. :::::: ..::.:...::::..:..:: . : : ::::::::
NP_000 PARPSAFAVLVTGLAATDLLGTSFLSPAVFVAYARNSSLLGLARGGPALCDAFAFAMTFF
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE2 SLATMLMLFAMALERYLSIGHPYFY-QRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQY
.::.::.:::::.:: :...:::.: : : . :: ::.::: .:::.:::: ::.
NP_000 GLASMLILFAMAVERCLALSHPYLYAQLDGPRCARLA-LPAIYAFCVLFCALPLLGLGQH
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE2 VQYCPGTWCFIRH-----GRTAYLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSR
:::::.:::.: : .:. :: :. ::..... :: :: :.: ::.:...: .
NP_000 QQYCPGSWCFLRMRWAQPGGAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQ
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE2 CGPSLGSGRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTI--FAYMNETSS
: :: : :: .:.:::::::.::...::::::.:: :. .:
NP_000 -------GSLGPRPRT-GE-----DEVDHLILLALMTVVMAVCSLPLTIRCFTQAVAPDS
230 240 250 260
300 310 320 330 340 350
pF1KE2 RKEKWDLQALRFLSINSIIDPWVFAILRPPVLRLMRSVLCCRISLRTQDATQTSCSTQSD
.: :: :.:: ..: :.::::: ..: :.. .. .::
NP_000 SSEMGDLLAFRFYAFNPILDPWVFILFRKAVFQRLKLWVCCLCLGPAHGDSQTPLSQLAS
270 280 290 300 310 320
pF1KE2 ASKQADL
NP_000 GRRDPRAPSAPVGKEGSCVPLSAWGEGQVEPLPPTQQSSGSAVGTSSKAEASVACSLC
330 340 350 360 370 380
>>NP_000944 (OMIM: 604687,607277) prostaglandin D2 recep (359 aa)
initn: 916 init1: 345 opt: 773 Z-score: 853.8 bits: 166.5 E(85289): 8.1e-41
Smith-Waterman score: 895; 44.4% identity (68.5% similar) in 356 aa overlap (13-350:8-357)
10 20 30 40 50 60
pF1KE2 MGNASNDSQSEDCETRQWLPPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGR
:.. . :.: ....:.::.:.::::.::.:::: : ::
NP_000 MKSPFYRCQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLG--WCSRRP
10 20 30 40 50
70 80 90 100 110
pF1KE2 RSSL-SLFHVLVTELVFTDLLGTCLISPVVLASYARNQTLVALAP--ESRACTYFAFAMT
: :.:..:: :. ::::: ::.::::::.::.:..: .::: .. : ::: :.
NP_000 LRPLPSVFYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 FFSLATMLMLFAMALERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQ
::.:.. :.:.::::: .::.:::.::.:... : : ::. : :: ::.::.. .:.
NP_000 FFGLSSTLQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE2 YVQYCPGTWCFIR--H--GRTAYLQ---LYATLLLLLIVSVLACNFSVILNLIRMHRRSR
.:::::::::::. : : . : ::..:. ::..... ::.... :: :::: .
NP_000 FVQYCPGTWCFIQMVHEEGSLSVLGYSVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQ
180 190 200 210 220 230
240 250 260 270 280
pF1KE2 RSRCGP-SLGSGRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIFAYMNET
: : : . : : : . :: :::.:::.::. :..:::: ::..
NP_000 RH---PRSCTRDCAEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIYRAYYGAF
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE2 SSRKEK-------WDLQALRFLSINSIIDPWVFAILRPPVLRLMRSVLCCRISLRTQDAT
.. ::: ::.::::::. ::.:::.: :.: ::.:.. . : :: ..
NP_000 KDVKEKNRTSEEAEDLRALRFLSVISIVDPWIFIIFRSPVFRIFFHKIFIR-PLRYRSRC
300 310 320 330 340
350
pF1KE2 QTSCSTQSDASKQADL
..: . .:
NP_000 SNSTNMESSL
350
>>XP_005267948 (OMIM: 604687,607277) PREDICTED: prostagl (359 aa)
initn: 916 init1: 345 opt: 773 Z-score: 853.8 bits: 166.5 E(85289): 8.1e-41
Smith-Waterman score: 895; 44.4% identity (68.5% similar) in 356 aa overlap (13-350:8-357)
10 20 30 40 50 60
pF1KE2 MGNASNDSQSEDCETRQWLPPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGR
:.. . :.: ....:.::.:.::::.::.:::: : ::
XP_005 MKSPFYRCQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLG--WCSRRP
10 20 30 40 50
70 80 90 100 110
pF1KE2 RSSL-SLFHVLVTELVFTDLLGTCLISPVVLASYARNQTLVALAP--ESRACTYFAFAMT
: :.:..:: :. ::::: ::.::::::.::.:..: .::: .. : ::: :.
XP_005 LRPLPSVFYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 FFSLATMLMLFAMALERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQ
::.:.. :.:.::::: .::.:::.::.:... : : ::. : :: ::.::.. .:.
XP_005 FFGLSSTLQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE2 YVQYCPGTWCFIR--H--GRTAYLQ---LYATLLLLLIVSVLACNFSVILNLIRMHRRSR
.:::::::::::. : : . : ::..:. ::..... ::.... :: :::: .
XP_005 FVQYCPGTWCFIQMVHEEGSLSVLGYSVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQ
180 190 200 210 220 230
240 250 260 270 280
pF1KE2 RSRCGP-SLGSGRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIFAYMNET
: : : . : : : . :: :::.:::.::. :..:::: ::..
XP_005 RH---PRSCTRDCAEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIYRAYYGAF
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE2 SSRKEK-------WDLQALRFLSINSIIDPWVFAILRPPVLRLMRSVLCCRISLRTQDAT
.. ::: ::.::::::. ::.:::.: :.: ::.:.. . : :: ..
XP_005 KDVKEKNRTSEEAEDLRALRFLSVISIVDPWIFIIFRSPVFRIFFHKIFIR-PLRYRSRC
300 310 320 330 340
350
pF1KE2 QTSCSTQSDASKQADL
..: . .:
XP_005 SNSTNMESSL
350
>>NP_001268398 (OMIM: 604687,607277) prostaglandin D2 re (296 aa)
initn: 771 init1: 345 opt: 759 Z-score: 839.4 bits: 163.6 E(85289): 5.1e-40
Smith-Waterman score: 759; 46.1% identity (69.9% similar) in 282 aa overlap (13-283:8-284)
10 20 30 40 50 60
pF1KE2 MGNASNDSQSEDCETRQWLPPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGR
:.. . :.: ....:.::.:.::::.::.:::: : ::
NP_001 MKSPFYRCQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLG--WCSRRP
10 20 30 40 50
70 80 90 100 110
pF1KE2 RSSL-SLFHVLVTELVFTDLLGTCLISPVVLASYARNQTLVALAP--ESRACTYFAFAMT
: :.:..:: :. ::::: ::.::::::.::.:..: .::: .. : ::: :.
NP_001 LRPLPSVFYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 FFSLATMLMLFAMALERYLSIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQ
::.:.. :.:.::::: .::.:::.::.:... : : ::. : :: ::.::.. .:.
NP_001 FFGLSSTLQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE2 YVQYCPGTWCFIR--H--GRTAYLQ---LYATLLLLLIVSVLACNFSVILNLIRMHRRSR
.:::::::::::. : : . : ::..:. ::..... ::.... :: :::: .
NP_001 FVQYCPGTWCFIQMVHEEGSLSVLGYSVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQ
180 190 200 210 220 230
240 250 260 270 280
pF1KE2 RSRCGP-SLGSGRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIFAYMNET
: : : . : : : . :: :::.:::.::. :..:::: :
NP_001 RH---PRSCTRDCAEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIAFVPGVPA
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE2 SSRKEKWDLQALRFLSINSIIDPWVFAILRPPVLRLMRSVLCCRISLRTQDATQTSCSTQ
NP_001 KTPGSR
>>XP_005259150 (OMIM: 600022) PREDICTED: prostacyclin re (342 aa)
initn: 665 init1: 346 opt: 663 Z-score: 733.6 bits: 144.2 E(85289): 4e-34
Smith-Waterman score: 724; 47.5% identity (70.7% similar) in 280 aa overlap (10-282:2-257)
10 20 30 40 50 60
pF1KE2 MGNASNDSQSEDCETRQWLPPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGR
...:.. .. . .:: :..:: :::.:: .::..: :: :
XP_005 MADSCRNLTYVRGSVGPATSTLMFVAGVVGNGLALGIL----------SARR
10 20 30 40
70 80 90 100 110
pF1KE2 RSSLSLFHVLVTELVFTDLLGTCLISPVVLASYARNQTLVALAPESRA-CTYFAFAMTFF
. : : :::: :. :::::: ..::.:...::::..:..:: . : : ::::::::
XP_005 PARPSAFAVLVTGLAATDLLGTSFLSPAVFVAYARNSSLLGLARGGPALCDAFAFAMTFF
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE2 SLATMLMLFAMALERYLSIGHPYFY-QRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQY
.::.::.:::::.:: :...:::.: : : . :: ::.::: .:::.:::: ::.
XP_005 GLASMLILFAMAVERCLALSHPYLYAQLDGPRCARLA-LPAIYAFCVLFCALPLLGLGQH
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE2 VQYCPGTWCFIRH-----GRTAYLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSR
:::::.:::.: : .:. :: :. ::..... :: :: :.: ::.:...: .
XP_005 QQYCPGSWCFLRMRWAQPGGAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQ
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE2 CGPSLGSGRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIFAYMNETSSRK
: :: : :: .:.:::::::.::...::::::.:.
XP_005 -------GSLGPRPRT-GE-----DEVDHLILLALMTVVMAVCSLPLTMRGSVFRPVTQS
230 240 250 260
300 310 320 330 340 350
pF1KE2 EKWDLQALRFLSINSIIDPWVFAILRPPVLRLMRSVLCCRISLRTQDATQTSCSTQSDAS
XP_005 QVLVLGPSIVEPDLPPTWLPSASEQAPPLPLHLGFLRGPRPAPPQWEWHRPWYPLSVCDT
270 280 290 300 310 320
>>XP_005259152 (OMIM: 600022) PREDICTED: prostacyclin re (257 aa)
initn: 655 init1: 346 opt: 661 Z-score: 732.8 bits: 143.7 E(85289): 4.5e-34
Smith-Waterman score: 722; 47.7% identity (70.6% similar) in 279 aa overlap (10-281:2-256)
10 20 30 40 50 60
pF1KE2 MGNASNDSQSEDCETRQWLPPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGR
...:.. .. . .:: :..:: :::.:: .::..: :: :
XP_005 MADSCRNLTYVRGSVGPATSTLMFVAGVVGNGLALGIL----------SARR
10 20 30 40
70 80 90 100 110
pF1KE2 RSSLSLFHVLVTELVFTDLLGTCLISPVVLASYARNQTLVALAPESRA-CTYFAFAMTFF
. : : :::: :. :::::: ..::.:...::::..:..:: . : : ::::::::
XP_005 PARPSAFAVLVTGLAATDLLGTSFLSPAVFVAYARNSSLLGLARGGPALCDAFAFAMTFF
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE2 SLATMLMLFAMALERYLSIGHPYFY-QRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQY
.::.::.:::::.:: :...:::.: : : . :: ::.::: .:::.:::: ::.
XP_005 GLASMLILFAMAVERCLALSHPYLYAQLDGPRCARLA-LPAIYAFCVLFCALPLLGLGQH
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE2 VQYCPGTWCFIRH-----GRTAYLQLYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSR
:::::.:::.: : .:. :: :. ::..... :: :: :.: ::.:...: .
XP_005 QQYCPGSWCFLRMRWAQPGGAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQ
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE2 CGPSLGSGRGGPGARRRGERVSMAEETDHLILLAIMTITFAVCSLPFTIFAYMNETSSRK
: :: : :: .:.:::::::.::...::::::.:
XP_005 -------GSLGPRPRT-GE-----DEVDHLILLALMTVVMAVCSLPLTQ
230 240 250
300 310 320 330 340 350
pF1KE2 EKWDLQALRFLSINSIIDPWVFAILRPPVLRLMRSVLCCRISLRTQDATQTSCSTQSDAS
>>XP_016865148 (OMIM: 601586) PREDICTED: prostaglandin E (313 aa)
initn: 472 init1: 237 opt: 403 Z-score: 449.2 bits: 91.5 E(85289): 2.8e-18
Smith-Waterman score: 482; 35.1% identity (62.3% similar) in 302 aa overlap (24-295:19-303)
10 20 30 40 50
pF1KE2 MGNASNDSQSEDCETRQWLPPGESPA-ISSVMFSAGVLGNLIALALLARRWRGDVGCSAG
::. : .::: ::.:::.:...: :..
XP_016 MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVL---------CKSR
10 20 30 40
60 70 80 90 100 110
pF1KE2 RRSSLSLFHVLVTELVFTDLLGTCLISPVVLASYARNQTLVALAPESRA-CTYFAFAMTF
.... . :..:: :. :::::: :.:::..:.: ..: : .. : : .: . :
XP_016 KEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKGQW-----PGGQPLCEYSTFILLF
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE2 FSLATMLMLFAMALERYLSIGHPYFYQRRVS-RSGGLAVLPVIYAVSLLFCSLPLLDYGQ
:::. . .. ::..::::.:.: :::.. :. : .::... : :: ..:::.:: . :.
XP_016 FSLSGLSIICAMSVERYLAINHAYFYSHYVDKRLAGLTLFAV-YASNVLFCALPNMGLGS
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE2 -YVQYCPGTWCFIR-----HGRTAYLQLYATLLLLLIVSVLACNFSVILNLIRMHRR-SR
.:: : ::::: ...:: .:: . .::.... :: : :.::::. :
XP_016 SRLQY-PDTWCFIDWTTNVTAHAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMR
170 180 190 200 210
240 250 260 270
pF1KE2 RSRCGP---------SLGSGRGGPGA-----------RRRGERVSMAEETDHLILLAIMT
:. : :..: :: :.: :::. : . : . .::: .
XP_016 RTSLGTEQHHAAAAASVAS-RGHPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATS
220 230 240 250 260 270
280 290 300 310 320 330
pF1KE2 ITFAVCSLPFTIFAYMNETSSRKEKWDLQALRFLSINSIIDPWVFAILRPPVLRLMRSVL
.. .::.:.. . ... . . .:
XP_016 LVVLICSIPLVAINPISHHGREGQKRTPVTFPKNV
280 290 300 310
>>XP_016865147 (OMIM: 601586) PREDICTED: prostaglandin E (325 aa)
initn: 472 init1: 237 opt: 403 Z-score: 449.1 bits: 91.5 E(85289): 2.8e-18
Smith-Waterman score: 481; 36.6% identity (62.4% similar) in 287 aa overlap (24-280:19-288)
10 20 30 40 50
pF1KE2 MGNASNDSQSEDCETRQWLPPGESPA-ISSVMFSAGVLGNLIALALLARRWRGDVGCSAG
::. : .::: ::.:::.:...: :..
XP_016 MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVL---------CKSR
10 20 30 40
60 70 80 90 100 110
pF1KE2 RRSSLSLFHVLVTELVFTDLLGTCLISPVVLASYARNQTLVALAPESRA-CTYFAFAMTF
.... . :..:: :. :::::: :.:::..:.: ..: : .. : : .: . :
XP_016 KEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKGQW-----PGGQPLCEYSTFILLF
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE2 FSLATMLMLFAMALERYLSIGHPYFYQRRVS-RSGGLAVLPVIYAVSLLFCSLPLLDYGQ
:::. . .. ::..::::.:.: :::.. :. : .::... : :: ..:::.:: . :.
XP_016 FSLSGLSIICAMSVERYLAINHAYFYSHYVDKRLAGLTLFAV-YASNVLFCALPNMGLGS
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE2 -YVQYCPGTWCFIR-----HGRTAYLQLYATLLLLLIVSVLACNFSVILNLIRMHRR-SR
.:: : ::::: ...:: .:: . .::.... :: : :.::::. :
XP_016 SRLQY-PDTWCFIDWTTNVTAHAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMR
170 180 190 200 210
240 250 260 270
pF1KE2 RSRCGP---------SLGSGRGGPGA-----------RRRGERVSMAEETDHLILLAIMT
:. : :..: :: :.: :::. : . : . .::: .
XP_016 RTSLGTEQHHAAAAASVAS-RGHPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATS
220 230 240 250 260 270
280 290 300 310 320 330
pF1KE2 ITFAVCSLPFTIFAYMNETSSRKEKWDLQALRFLSINSIIDPWVFAILRPPVLRLMRSVL
.. .::.:.
XP_016 LVVLICSIPLVANWKWSHKTTDGMSDECEAHLYIQEKCHKFGFPSCK
280 290 300 310 320
>>XP_016865146 (OMIM: 601586) PREDICTED: prostaglandin E (326 aa)
initn: 472 init1: 237 opt: 403 Z-score: 449.0 bits: 91.5 E(85289): 2.8e-18
Smith-Waterman score: 481; 36.6% identity (62.4% similar) in 287 aa overlap (24-280:19-288)
10 20 30 40 50
pF1KE2 MGNASNDSQSEDCETRQWLPPGESPA-ISSVMFSAGVLGNLIALALLARRWRGDVGCSAG
::. : .::: ::.:::.:...: :..
XP_016 MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVL---------CKSR
10 20 30 40
60 70 80 90 100 110
pF1KE2 RRSSLSLFHVLVTELVFTDLLGTCLISPVVLASYARNQTLVALAPESRA-CTYFAFAMTF
.... . :..:: :. :::::: :.:::..:.: ..: : .. : : .: . :
XP_016 KEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKGQW-----PGGQPLCEYSTFILLF
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE2 FSLATMLMLFAMALERYLSIGHPYFYQRRVS-RSGGLAVLPVIYAVSLLFCSLPLLDYGQ
:::. . .. ::..::::.:.: :::.. :. : .::... : :: ..:::.:: . :.
XP_016 FSLSGLSIICAMSVERYLAINHAYFYSHYVDKRLAGLTLFAV-YASNVLFCALPNMGLGS
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE2 -YVQYCPGTWCFIR-----HGRTAYLQLYATLLLLLIVSVLACNFSVILNLIRMHRR-SR
.:: : ::::: ...:: .:: . .::.... :: : :.::::. :
XP_016 SRLQY-PDTWCFIDWTTNVTAHAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMR
170 180 190 200 210
240 250 260 270
pF1KE2 RSRCGP---------SLGSGRGGPGA-----------RRRGERVSMAEETDHLILLAIMT
:. : :..: :: :.: :::. : . : . .::: .
XP_016 RTSLGTEQHHAAAAASVAS-RGHPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATS
220 230 240 250 260 270
280 290 300 310 320 330
pF1KE2 ITFAVCSLPFTIFAYMNETSSRKEKWDLQALRFLSINSIIDPWVFAILRPPVLRLMRSVL
.. .::.:.
XP_016 LVVLICSIPLVFPKLQMKNLYHSATYRVAIGASIRQPVISAKFGARSQ
280 290 300 310 320
358 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 14:26:14 2016 done: Sun Nov 6 14:26:15 2016
Total Scan time: 8.530 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]