Result of FASTA (ccds) for
pFN21AE2289
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2289, 508 aa
1>>>pF1KE2289 508 - 508 aa - 508 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.7330+/-0.000793; mu= 11.7723+/- 0.048
mean_var=97.1968+/-19.206, 0's: 0 Z-trim(110.5): 35 B-trim: 0 in 0/51
Lambda= 0.130091
statistics sampled from 11654 (11688) to 11654 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.725), E-opt: 0.2 (0.359), width: 16
Scan time: 3.070
The best scores are: opt bits E(32554)
CCDS8895.1 MMP19 gene_id:4327|Hs108|chr12 ( 508) 3547 675.9 2.8e-194
CCDS61146.1 MMP19 gene_id:4327|Hs108|chr12 ( 305) 1190 233.5 2.7e-61
CCDS13816.1 MMP11 gene_id:4320|Hs108|chr22 ( 488) 854 170.5 3.9e-42
CCDS8321.1 MMP10 gene_id:4319|Hs108|chr11 ( 476) 848 169.3 8.3e-42
CCDS8323.1 MMP3 gene_id:4314|Hs108|chr11 ( 477) 805 161.3 2.2e-39
CCDS8318.1 MMP20 gene_id:9313|Hs108|chr11 ( 483) 723 145.9 9.7e-35
CCDS74036.1 MMP28 gene_id:79148|Hs108|chr17 ( 520) 658 133.7 4.8e-31
CCDS8324.1 MMP13 gene_id:4322|Hs108|chr11 ( 471) 654 132.9 7.5e-31
CCDS9577.1 MMP14 gene_id:4323|Hs108|chr14 ( 582) 633 129.0 1.4e-29
CCDS76996.1 MMP28 gene_id:79148|Hs108|chr17 ( 393) 614 125.4 1.2e-28
CCDS8319.1 MMP27 gene_id:64066|Hs108|chr11 ( 513) 609 124.5 2.8e-28
CCDS73375.1 MMP12 gene_id:4321|Hs108|chr11 ( 470) 607 124.1 3.4e-28
CCDS8322.1 MMP1 gene_id:4312|Hs108|chr11 ( 469) 589 120.7 3.5e-27
CCDS8317.1 MMP7 gene_id:4316|Hs108|chr11 ( 267) 507 105.2 9.2e-23
CCDS46593.1 MMP24 gene_id:10893|Hs108|chr20 ( 645) 497 103.5 7.3e-22
CCDS7752.1 MMP26 gene_id:56547|Hs108|chr11 ( 261) 475 99.2 5.8e-21
CCDS6246.1 MMP16 gene_id:4325|Hs108|chr8 ( 607) 479 100.1 7.2e-21
CCDS8320.1 MMP8 gene_id:4317|Hs108|chr11 ( 467) 470 98.4 1.8e-20
CCDS7647.1 MMP21 gene_id:118856|Hs108|chr10 ( 569) 421 89.2 1.3e-17
CCDS31927.1 MMP17 gene_id:4326|Hs108|chr12 ( 603) 381 81.7 2.5e-15
CCDS30559.1 MMP23B gene_id:8510|Hs108|chr1 ( 390) 371 79.8 6.2e-15
CCDS13390.1 MMP9 gene_id:4318|Hs108|chr20 ( 707) 353 76.5 1.1e-13
CCDS10752.1 MMP2 gene_id:4313|Hs108|chr16 ( 660) 346 75.2 2.5e-13
CCDS45487.1 MMP2 gene_id:4313|Hs108|chr16 ( 610) 343 74.6 3.5e-13
CCDS10492.1 MMP25 gene_id:64386|Hs108|chr16 ( 562) 337 73.5 7.1e-13
CCDS76869.1 MMP2 gene_id:4313|Hs108|chr16 ( 584) 328 71.8 2.4e-12
CCDS10792.1 MMP15 gene_id:4324|Hs108|chr16 ( 669) 301 66.7 8.9e-11
>>CCDS8895.1 MMP19 gene_id:4327|Hs108|chr12 (508 aa)
initn: 3547 init1: 3547 opt: 3547 Z-score: 3601.3 bits: 675.9 E(32554): 2.8e-194
Smith-Waterman score: 3547; 100.0% identity (100.0% similar) in 508 aa overlap (1-508:1-508)
10 20 30 40 50 60
pF1KE2 MNCQQLWLGFLLPMTVSGRVLGLAEVAPVDYLSQYGYLQKPLEGSNNFKPEDITEALRAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 MNCQQLWLGFLLPMTVSGRVLGLAEVAPVDYLSQYGYLQKPLEGSNNFKPEDITEALRAF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLLLGRWRKKHLTFRILNLPSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 QEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLLLGRWRKKHLTFRILNLPSTL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 PPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPGRVLAHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 PPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPGRVLAHA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 DIPELGSVHFDEDEFWTEGTYRGVNLRIIAAHEVGHALGLGHSRYSQALMAPVYEGYRPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 DIPELGSVHFDEDEFWTEGTYRGVNLRIIAAHEVGHALGLGHSRYSQALMAPVYEGYRPH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 FKLHPDDVAGIQALYGKKSPVIRDEEEEETELPTVPPVPTEPSPMPDPCSSELDAMMLGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 FKLHPDDVAGIQALYGKKSPVIRDEEEEETELPTVPPVPTEPSPMPDPCSSELDAMMLGP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 RGKTYAFKGDYVWTVSDSGPGPLFRVSALWEGLPGNLDAAVYSPRTQWIHFFKGDKVWRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 RGKTYAFKGDYVWTVSDSGPGPLFRVSALWEGLPGNLDAAVYSPRTQWIHFFKGDKVWRY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 INFKMSPGFPKKLNRVEPNLDAALYWPLNQKVFLFKGSGYWQWDELARTDFSSYPKPIKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 INFKMSPGFPKKLNRVEPNLDAALYWPLNQKVFLFKGSGYWQWDELARTDFSSYPKPIKG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 LFTGVPNQPSAAMSWQDGRVYFFKGKVYWRLNQQLRVEKGYPRNISHNWMHCRPRTIDTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS88 LFTGVPNQPSAAMSWQDGRVYFFKGKVYWRLNQQLRVEKGYPRNISHNWMHCRPRTIDTT
430 440 450 460 470 480
490 500
pF1KE2 PSGGNTTPSGTGITLDTTLSATETTFEY
::::::::::::::::::::::::::::
CCDS88 PSGGNTTPSGTGITLDTTLSATETTFEY
490 500
>>CCDS61146.1 MMP19 gene_id:4327|Hs108|chr12 (305 aa)
initn: 1190 init1: 1190 opt: 1190 Z-score: 1214.0 bits: 233.5 E(32554): 2.7e-61
Smith-Waterman score: 1313; 67.0% identity (68.7% similar) in 342 aa overlap (1-333:1-258)
10 20 30 40 50 60
pF1KE2 MNCQQLWLGFLLPMTVSGRVLGLAEVAPVDYLSQYGYLQKPLEGSNNFKPEDITEALRAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 MNCQQLWLGFLLPMTVSGRVLGLAEVAPVDYLSQYGYLQKPLEGSNNFKPEDITEALRAF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLLLGRWRKKHLTFRILNLPSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 QEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLLLGRWRKKHLTFRILNLPSTL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 PPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPGRVLAHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 PPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPG------
130 140 150 160 170
190 200 210 220 230 240
pF1KE2 DIPELGSVHFDEDEFWTEGTYRGVNLRIIAAHEVGHALGLGHSRYSQALMAPVYEGYRPH
CCDS61 ------------------------------------------------------------
250 260 270 280 290 300
pF1KE2 FKLHPDDVAGIQALYGKKSPVIRDEEEEETELPTVPPVPTEPSPMPDPCSSELDAMMLGP
:::::::::::::::::::::::::::::::::::::::::::
CCDS61 ----------------KKSPVIRDEEEEETELPTVPPVPTEPSPMPDPCSSELDAMMLGE
180 190 200 210
310 320 330 340 350
pF1KE2 R------GKTYAFKGD-YVWTV-SDSG-PGPLFRVSALWEGLPGNLDAAVYSPRTQWIHF
:. .. .: .:: :: : .: : :: :
CCDS61 APPLQAVGRRWGQPADPEAWTNGSDMGLQHEQWR--APWEDLCFQGGLCVDCIRFRTGPL
220 230 240 250 260 270
360 370 380 390 400 410
pF1KE2 FKGDKVWRYINFKMSPGFPKKLNRVEPNLDAALYWPLNQKVFLFKGSGYWQWDELARTDF
CCDS61 VPSVCPLGGAPRKPGCCCLLASNTMDSLL
280 290 300
>>CCDS13816.1 MMP11 gene_id:4320|Hs108|chr22 (488 aa)
initn: 657 init1: 180 opt: 854 Z-score: 870.0 bits: 170.5 E(32554): 3.9e-42
Smith-Waterman score: 854; 36.0% identity (63.3% similar) in 411 aa overlap (80-472:75-480)
50 60 70 80 90 100
pF1KE2 PEDITEALRAFQEASELPVSGQLDDATRARMRQPRCGLEDPFN----QKTLKYLLL--GR
.: ::::. :: . .. : ..: ::
CCDS13 RRGPQPWHAALPSSPAPAPATQEAPRPASSLRPPRCGVPDPSDGLSARNRQKRFVLSGGR
50 60 70 80 90 100
110 120 130 140 150 160
pF1KE2 WRKKHLTFRILNLPSTLPPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHGRQS
:.: ::.::: .: : . .: .. .:.. ::.:.:::: ::. : ::: ..: .:
CCDS13 WEKTDLTYRILRFPWQLVQEQVRQTMAEALKVWSDVTPLTFTEVHEGRADIMIDF-ARYW
110 120 130 140 150 160
170 180 190 200 210 220
pF1KE2 SYCSNTFDGPGRVLAHADIPEL---GSVHFDEDEFWTEGTYRGVNLRIIAAHEVGHALGL
. ::::: .:::: .:. :.:::: :: :: : .:..: .:::: ::.:::
CCDS13 HGDDLPFDGPGGILAHAFFPKTHREGDVHFDYDETWTIGDDQGTDLLQVAAHEFGHVLGL
170 180 190 200 210 220
230 240 250 260 270
pF1KE2 GHSRYSQALMAPVYEGYRPHFKLHPDDVAGIQALYGKKSPVIRDEEEE---ETELPTVPP
:. ..:::. : .: ..: ::: :.: :::. :.. .. .. . :
CCDS13 QHTTAAKALMSAFYT-FRYPLSLSPDDCRGVQHLYGQPWPTVTSRTPALGPQAGIDTNEI
230 240 250 260 270 280
280 290 300 310 320 330
pF1KE2 VPTEPSPMPDPCSSELDAMMLGPRGKTYAFKGDYVWTVSDSG--PGPLFRVSALWEGLPG
.: ::. :: : . .::. ::. . ::. .:: . . :: .: :.:::.
CCDS13 APLEPDAPPDACEASFDAVST-IRGELFFFKAGFVWRLRGGQLQPGYPALASRHWQGLPS
290 300 310 320 330 340
340 350 360 370 380 390
pF1KE2 NLDAAVYSPRTQWIHFFKGDKVWRYINFK--MSPGFPKKLNRVEPNLDAALYW-PLNQKV
.::: . . . : ::.: . : : . : ..:. .:. :. . ::: : : ..:.
CCDS13 PVDAAFEDAQGH-IWFFQGAQYWVYDGEKPVLGPAPLTELGLVRFPVHAALVWGPEKNKI
350 360 370 380 390 400
400 410 420 430 440 450
pF1KE2 FLFKGSGYWQWDELARTDFSSYPKPIKGLFTGVPNQPSAAMSWQDGRVYFFKGKVYWRLN
..:.: ::.. .: : :. . :::.. .::.. :: .::..:..::...
CCDS13 YFFRGRDYWRFHPSTRRVDSPVPRRATD-WRGVPSEIDAAFQDADGYAYFLRGRLYWKFD
410 420 430 440 450
460 470 480 490 500
pF1KE2 Q-QLRVEKGYPRNISHNWMHCRPRTIDTTPSGGNTTPSGTGITLDTTLSATETTFEY
.... .:.:: .. ... :
CCDS13 PVKVKALEGFPRLVGPDFFGCAEPANTFL
460 470 480
>>CCDS8321.1 MMP10 gene_id:4319|Hs108|chr11 (476 aa)
initn: 645 init1: 178 opt: 848 Z-score: 864.1 bits: 169.3 E(32554): 8.3e-42
Smith-Waterman score: 848; 35.2% identity (62.0% similar) in 460 aa overlap (31-472:37-476)
10 20 30 40 50
pF1KE2 MNCQQLWLGFLLPMTVSGRVLGLAEVAPVDYLSQYGYLQKPLEGSNNFKPED---ITEAL
:: .: :.: .. .:. .: :.. .
CCDS83 LVLLCLPVCSAYPLSGAAKEEDSNKDLAQQYLEKYYNLEKDVK---QFRRKDSNLIVKKI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 RAFQEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLLLGRWRKKHLTFRILNLP
...:. : :.:.:: : ::.::::. : . ... . .::: :::.::.:
CCDS83 QGMQKFLGLEVTGKLDTDTLEVMRKPRCGVPDVGHFSSFPGM--PKWRKTHLTYRIVNYT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 STLPPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPGRVL
:: .. .:...:.. : .:.::::... : ::: .:: .. . .:::::. :
CCDS83 PDLPRDAVDSAIEKALKVWEEVTPLTFSRLYEGEADIMISFAVKEHGDFY-SFDGPGHSL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE2 AHADIPE---LGSVHFDEDEFWTEGTYRGVNLRIIAAHEVGHALGLGHSRYSQALMAPVY
::: : :..:::.:: ::: . :.:: ..::::.::.::: :: ..::: :.:
CCDS83 AHAYPPGPGLYGDIHFDDDEKWTEDA-SGTNLFLVAAHELGHSLGLFHSANTEALMYPLY
190 200 210 220 230
240 250 260 270 280 290
pF1KE2 EGYRP--HFKLHPDDVAGIQALYGKKSPVIRDEEEEETELPTVPP--VPTEPSPMPDPCS
... .:.: ::: :::.::: : :: : :: ::. : :: :.
CCDS83 NSFTELAQFRLSQDDVNGIQSLYGP--PPASTEE------PLVPTKSVPS-GSEMPAKCD
240 250 260 270 280 290
300 310 320 330 340
pF1KE2 SEL--DAMMLGPRGKTYAFKGDYVWTVSDSGPGPLFR-VSALWEGLPGNLDAAVYSPRTQ
: ::. ::. :: : : : .: : :. .::.: .::. :::: .
CCDS83 PALSFDAISTL-RGEYLFFKDRYFWRRSHWNPEPEFHLISAFWPSLPSYLDAAYEVNSRD
300 310 320 330 340
350 360 370 380 390 400
pF1KE2 WIHFFKGDKVWRYINFKMSPGFPKKLNRV--EPNL---DAALYWPLNQKVFLFKGSGYWQ
. .:::.. : . ... :.:. .. . :.. :::. ..:...: .. ::.
CCDS83 TVFIFKGNEFWAIRGNEVQAGYPRGIHTLGFPPTIRKIDAAVSDKEKKKTYFFAADKYWR
350 360 370 380 390 400
410 420 430 440 450 460
pF1KE2 WDELARTDFSSYPKPIKGLFTGVPNQPSAAMSWQDGRVYFFKGKVYWRLNQQLRVEKGYP
.:: ... ...:. : : :: . .:... : :::.:. .... . :.
CCDS83 FDENSQSMEQGFPRLIADDFPGVEPKVDAVLQ-AFGFFYFFSGSSQFEFDPNARMVTHIL
410 420 430 440 450 460
470 480 490 500
pF1KE2 RNISHNWMHCRPRTIDTTPSGGNTTPSGTGITLDTTLSATETTFEY
. :..:.::
CCDS83 K--SNSWLHC
470
>>CCDS8323.1 MMP3 gene_id:4314|Hs108|chr11 (477 aa)
initn: 720 init1: 181 opt: 805 Z-score: 820.5 bits: 161.3 E(32554): 2.2e-39
Smith-Waterman score: 805; 34.5% identity (59.2% similar) in 458 aa overlap (31-472:37-477)
10 20 30 40 50
pF1KE2 MNCQQLWLGFLLPMTVSGRVLGLAEVAPVDYLSQYGYLQKPLEGSNNFKPED-ITEALRA
:: .: :.: .. : ... .:
CCDS83 LLLLCVAVCSAYPLDGAARGEDTSMNLVQKYLENYYDLKKDVKQFVRRKDSGPVVKKIRE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 FQEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLLLGRWRKKHLTFRILNLPST
.:. : :.:.::. : ::.::::. : . .:. . .::: :::.::.:
CCDS83 MQKFLGLEVTGKLDSDTLEVMRKPRCGVPDVGHFRTFPGI--PKWRKTHLTYRIVNYTPD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 LPPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPGRVLAH
:: .. .:...:.. : .:.::::... : ::: .:: :. . ::::: ::::
CCDS83 LPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFY-PFDGPGNVLAH
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE2 ADIPELG---SVHFDEDEFWTEGTYRGVNLRIIAAHEVGHALGLGHSRYSQALMAPVYEG
: : : ..:::.:: ::. : :.:: ..::::.::.::: :: ..::: :.:..
CCDS83 AYAPGPGINGDAHFDDDEQWTKDT-TGTNLFLVAAHEIGHSLGLFHSANTEALMYPLYHS
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE2 YRP--HFKLHPDDVAGIQALYGKKSPVIRDEEEEETELPTVP--PVPTEPSPMPDPCSSE
.:.: ::. :::.::: : . : : :: ::: ::. : :.
CCDS83 LTDLTRFRLSQDDINGIQSLYGPP-P-------DSPETPLVPTEPVPPEPGT-PANCDPA
250 260 270 280 290
300 310 320 330 340
pF1KE2 L--DAMMLGPRGKTYAFKGDYVWTVSDSGPGP-LFRVSALWEGLPGNLDAAVYSPRTQWI
: ::. ::. :: . : : : : .:..: .::...::: . .
CCDS83 LSFDAVSTL-RGEILIFKDRHFWRKSLRKLEPELHLISSFWPSLPSGVDAAYEVTSKDLV
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE2 HFFKGDKVWRYINFKMSPGFPKKLNRV--EPN---LDAALYWPLNQKVFLFKGSGYWQWD
.:::.. : . .. :.:. .. . :. .:::. ..:...: . ::..:
CCDS83 FIFKGNQFWAIRGNEVRAGYPRGIHTLGFPPTVRKIDAAISDKEKNKTYFFVEDKYWRFD
360 370 380 390 400 410
410 420 430 440 450 460
pF1KE2 ELARTDFSSYPKPIKGLFTGVPNQPSAAMSWQDGRVYFFKGKVYWRLNQQLRVEKGYPRN
: . ..:: : : :. .. .:.. . : ::: :. ... . . :
CCDS83 EKRNSMEPGFPKQIAEDFPGIDSKIDAVFE-EFGFFYFFTGSSQLEFDPNAK--KVTHTL
420 430 440 450 460
470 480 490 500
pF1KE2 ISHNWMHCRPRTIDTTPSGGNTTPSGTGITLDTTLSATETTFEY
:..:..:
CCDS83 KSNSWLNC
470
>>CCDS8318.1 MMP20 gene_id:9313|Hs108|chr11 (483 aa)
initn: 486 init1: 143 opt: 723 Z-score: 737.2 bits: 145.9 E(32554): 9.7e-35
Smith-Waterman score: 723; 34.7% identity (58.2% similar) in 450 aa overlap (44-472:64-483)
20 30 40 50 60 70
pF1KE2 MTVSGRVLGLAEVAPVDYLSQYGYLQKPLEGSNNFKPEDITEALRAFQEASELPVSGQLD
:::. . . .. .: : :.:.::
CCDS83 WRNNYRLAQAYLDKYYTNKEGHQIGEMVARGSNS-----MIRKIKELQAFFGLQVTGKLD
40 50 60 70 80
80 90 100 110 120 130
pF1KE2 DATRARMRQPRCGLEDPFNQKTLKYLLLG--RWRKKHLTFRILNLPSTLPPHTARAALRQ
..: ...::::. : : . :. : .:.:. ::.:: . .. . :...
CCDS83 QTTMNVIKKPRCGVPDVANYR----LFPGEPKWKKNTLTYRISKYTPSMSSVEVDKAVEM
90 100 110 120 130 140
140 150 160 170 180
pF1KE2 AFQDWSNVAPLTFQEVQAGAADIRLSF-HGRQSSYCSNTFDGPGRVLAHADIPELG---S
:.: ::...::.: ....: ::: .:: .: ... : :::: .:::: : : .
CCDS83 ALQAWSSAVPLSFVRINSGEADIMISFENGDHGD--SYPFDGPRGTLAHAFAPGEGLGGD
150 160 170 180 190 200
190 200 210 220 230 240
pF1KE2 VHFDEDEFWTEGTYRGVNLRIIAAHEVGHALGLGHSRYSQALMAPVYEGYRPH-FKLHPD
.:::. : :: :: : :: .:::: ::::::.:: .::: :.:. :. :.: :
CCDS83 THFDNAEKWTMGT-NGFNLFTVAAHEFGHALGLAHSTDPSALMYPTYKYKNPYGFHLPKD
210 220 230 240 250 260
250 260 270 280 290 300
pF1KE2 DVAGIQALYGKKSPVIRDEEEEETELPTVPPVPTEPSPMPDPC--SSELDAM-MLGPRGK
:: ::::::: .. . ::.: .: . .:: : :: .::. ::: .
CCDS83 DVKGIQALYGPRKVFLGK--------PTLPHAPHHKPSIPDLCDSSSSFDAVTMLGK--E
270 280 290 300 310
310 320 330 340 350 360
pF1KE2 TYAFKGDYVWTVS---DSGPGPLFRVSALWEGLPGNLDAAVYSPRTQWIHFFKGDKVWRY
:: : . .: : ... . : .:.::: . .:::: . :
CCDS83 LLLFKDRIFWRRQVHLRTGIRPS-TITSSFPQLMSNVDAAYEVAERGTAYFFKGPHYWIT
320 330 340 350 360 370
370 380 390 400 410
pF1KE2 INFKMS-P-------GFPKKLNRVEPNLDAALYWPLNQKVFLFKGSGYWQWDELARTDFS
.:.:. : :::...... :::.: ::...: :. :...:: : .
CCDS83 RGFQMQGPPRTIYDFGFPRHVQQI----DAAVYLREPQKTLFFVGDEYYSYDERKRKMEK
380 390 400 410 420
420 430 440 450 460 470
pF1KE2 SYPKPIKGLFTGVPNQPSAAMSWQDGRVYFFKGKVYWRLNQQLRVEKGYPRNISHNWMHC
.::: . :.:: .: .::. .: .:::.: .. . . : : .:. :
CCDS83 DYPKNTEEEFSGVNGQIDAAVEL-NGYIYFFSGPKTYKYDTE--KEDVVSVVKSSSWIGC
430 440 450 460 470 480
480 490 500
pF1KE2 RPRTIDTTPSGGNTTPSGTGITLDTTLSATETTFEY
>>CCDS74036.1 MMP28 gene_id:79148|Hs108|chr17 (520 aa)
initn: 812 init1: 310 opt: 658 Z-score: 670.8 bits: 133.7 E(32554): 4.8e-31
Smith-Waterman score: 921; 36.6% identity (59.9% similar) in 481 aa overlap (31-472:39-510)
10 20 30 40 50 60
pF1KE2 MNCQQLWLGFLLPMTVSGRVLGLAEVAPVDYLSQYGYLQKPLEGSNNFKPEDITEALRAF
.: .::::.. . . . ...:.:::
CCDS74 LRALQLLLWGHLDAQPAERGGQELRKEAEAFLEKYGYLNEQVPKAPT--STRFSDAIRAF
10 20 30 40 50 60
70 80 90 100
pF1KE2 QEASELPVSGQLDDATRARMRQPRCGLEDP-------------FNQKTLK------YLLL
: .:.::::: :: :: .: .::::. : : .. : .
CCDS74 QWVSQLPVSGVLDRATLRQMTRPRCGVTDTNSYAAWAERISDLFARHRTKMRRKKRFAKQ
70 80 90 100 110 120
110 120 130 140 150
pF1KE2 G-RWRKKHLTFRILNLPSTLPPHTARAALRQAFQDWSNVAPLTFQEVQA-GAADIRLSF-
: .: :.::..:..: : :: ..:.:.: ::: ::::. : : :. : : :::::.:
CCDS74 GNKWYKQHLSYRLVNWPEHLPEPAVRGAVRAAFQLWSNVSALEFWEAPATGPADIRLTFF
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE2 HGRQSSYCSNTFDGPGRVLAHADIPELGSVHFDEDEFWTEGTYRGVNLRIIAAHEVGHAL
.: ... .:.::::: .:::: .:. : .:::.:: :. . :: :: .. :::.::.:
CCDS74 QGDHNDGLGNAFDGPGGALAHAFLPRRGEAHFDQDERWSLSRRRGRNLFVVLAHEIGHTL
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE2 GLGHSRYSQALMAPVYEGYRPHFKLHPDDVAGIQALYGKK---SPVIRDEEEEETELPT-
:: :: .::::: :. : ::: ..:.:::: : ... . :.. :
CCDS74 GLTHSPAPRALMAPYYKRLGRDALLSWDDVLAVQSLYGKPLGGSVAVQLPGKLFTDFETW
250 260 270 280 290 300
280 290 300 310 320
pF1KE2 --VPPVPTEPSPM-PDPCSSELDAMMLGPRGKTYAFKGDYVWTVSDSG----PGPLFRVS
: .: . : : : .::. . . . : :::.. : :. .: : :: .
CCDS74 DSYSPQGRRPETQGPKYCHSSFDAITVDRQQQLYIFKGSHFWEVAADGNVSEPRPL---Q
310 320 330 340 350 360
330 340 350 360 370 380
pF1KE2 ALWEGLPGNLDAAVYSPRTQWIHFFKGDKVWRYINFKMSPGFPK--KLNRVEPNLDAALY
: ::: :..::. : ..:::: . ::. . : :.:. . . . . ::::.
CCDS74 ERWVGLPPNIEAAAVSLNDGDFYFFKGGRCWRFRGPKPVWGLPQLCRAGGLPRHPDAALF
370 380 390 400 410 420
390 400 410 420 430 440
pF1KE2 WPLNQKVFLFKGSGYWQWDELARTDFSS---YPKPIKGLFTGVPNQPSAAMSWQDGRVYF
.: ....::::. :. ::: .. ::. .. . :.:.. :.:. :: . :
CCDS74 FPPLRRLILFKGARYYV---LARGGLQVEPYYPRSLQD-WGGIPEEVSGALPRPDGSIIF
430 440 450 460 470
450 460 470 480 490 500
pF1KE2 FKGKVYWRLNQ-QLRVEKGYPRNISHNWMHCRPRTIDTTPSGGNTTPSGTGITLDTTLSA
:. ::::.: .:.. . :: :
CCDS74 FRDDRYWRLDQAKLQATTSGRWATELPWMGCWHANSGSALF
480 490 500 510 520
pF1KE2 TETTFEY
>>CCDS8324.1 MMP13 gene_id:4322|Hs108|chr11 (471 aa)
initn: 552 init1: 158 opt: 654 Z-score: 667.4 bits: 132.9 E(32554): 7.5e-31
Smith-Waterman score: 793; 35.1% identity (60.9% similar) in 425 aa overlap (53-464:64-466)
30 40 50 60 70 80
pF1KE2 LAEVAPVDYLSQYGYLQKPLEGSNNFKPEDITEALRAFQEASELPVSGQLDDATRARMRQ
.:: :: .: : :.:.::: : :..
CCDS83 EDLQFAERYLRSYYHPTNLAGILKENAASSMTERLREMQSFFGLEVTGKLDDNTLDVMKK
40 50 60 70 80 90
90 100 110 120 130 140
pF1KE2 PRCGLEDPFNQKTLKYLLLGRWRKKHLTFRILNLPSTLPPHTARAALRQAFQDWSNVAPL
::::. : . ... : .: : .::.::.: . .. :...::. ::.:.::
CCDS83 PRCGVPDVGEYNVFPRTL--KWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPL
100 110 120 130 140 150
150 160 170 180 190
pF1KE2 TFQEVQAGAADIRLSFHGRQSSYCSNTFDGPGRVLAHADIP---ELGSVHFDEDEFWTEG
.: ... : ::: .:: : . ::::. .:::: : :..:::.:: :: .
CCDS83 NFTRLHDGIADIMISF-GIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSS
160 170 180 190 200 210
200 210 220 230 240 250
pF1KE2 TYRGVNLRIIAAHEVGHALGLGHSRYSQALMAPVYEGY-RPHFKLHPDDVAGIQALYGKK
. .: :: ..:::: ::.::: ::. ::: :.: . :: : ::: :::.:::
CCDS83 S-KGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPG
220 230 240 250 260
260 270 280 290 300 310
pF1KE2 SPVIRDEEEEETELPTVPPVPTEPSPMPDPC--SSELDAMMLGPRGKTYAFKGDYVWTVS
::. : : .:. :: : : :::. . ::.:. :: . : .
CCDS83 -----DED----------PNPKHPKT-PDKCDPSLSLDAIT-SLRGETMIFKDRFFWRLH
270 280 290 300 310
320 330 340 350 360 370
pF1KE2 DSG-PGPLFRVSALWEGLPGNLDAAVYSPRTQWIHFFKGDKVWRYINFKMSPGFPKKLNR
. . :: ....: ::. .::: : . : .:.: : : .. . :.:::...
CCDS83 PQQVDAELFLTKSFWPELPNRIDAAYEHPSHDLIFIFRGRKFWALNGYDILEGYPKKISE
320 330 340 350 360 370
380 390 400 410 420 430
pF1KE2 VE-PN----LDAALYWPLNQKVFLFKGSGYWQWDELARTDFSSYPKPIKGLFTGVPNQPS
. :. ..::... . :..::.:. :..:. . ..::. :. : :. .. .
CCDS83 LGLPKEVKKISAAVHFEDTGKTLLFSGNQVWRYDDTNHIMDKDYPRLIEEDFPGIGDKVD
380 390 400 410 420 430
440 450 460 470 480
pF1KE2 AAMSWQDGRVYFFKGKVYWRLN-QQLRVEKGYPRNISHNWMHCRPRTIDTTPSGGNTTPS
:.. ..: .:::.: . .. . . :. . .: :
CCDS83 AVYE-KNGYIYFFNGPIQFEYSIWSNRIVRVMPANSILWC
440 450 460 470
490 500
pF1KE2 GTGITLDTTLSATETTFEY
>>CCDS9577.1 MMP14 gene_id:4323|Hs108|chr14 (582 aa)
initn: 636 init1: 165 opt: 633 Z-score: 644.6 bits: 129.0 E(32554): 1.4e-29
Smith-Waterman score: 935; 35.1% identity (61.0% similar) in 521 aa overlap (10-484:11-512)
10 20 30 40 50
pF1KE2 MNCQQLWLGFLLPMTVSGRVL---GLAE---VAPVDYLSQYGYLQK-PLEGSNNFKPED
.:::. . : .: : :. .: .:.::::: :. .. .:..
CCDS95 MSPAPRPPRCLLLPLLTLGTALASLGSAQSSSFSPEAWLQQYGYLPPGDLRTHTQRSPQS
10 20 30 40 50 60
60 70 80 90 100
pF1KE2 ITEALRAFQEASELPVSGQLDDATRARMRQPRCGLEDPF------NQKTLKYLLLG-RWR
.. :. :.:. : :.:. : : ::.::::. : : : . .: . : .:.
CCDS95 LSAAIAAMQKFYGLQVTGKADADTMKAMRRPRCGVPDKFGAEIKANVRRKRYAIQGLKWQ
70 80 90 100 110 120
110 120 130 140 150
pF1KE2 KKHLTFRILNLPSTLPPHTARAALRQAFQDWSNVAPLTFQEV-----QAG---AADIRL-
....:: : : . ... :.:.::. : ...:: :.:: . : ::: .
CCDS95 HNEITFCIQNYTPKVGEYATYEAIRKAFRVWESATPLRFREVPYAYIREGHEKQADIMIF
130 140 150 160 170 180
160 170 180 190 200
pF1KE2 ---SFHGRQSSYCSNTFDGPGRVLAHADIPEL---GSVHFDEDEFWT--EGTYRGVNLRI
.::: :. ::: : :::: .: :..::: : :: . : .. .
CCDS95 FAEGFHGD-----STPFDGEGGFLAHAYFPGPNIGGDTHFDSAEPWTVRNEDLNGNDIFL
190 200 210 220 230
210 220 230 240 250 260
pF1KE2 IAAHEVGHALGLGHSRYSQALMAPVYEGY-RPHFKLHPDDVAGIQALYGKKS--PVIRDE
.:.::.:::::: :: .:.::: :. . .: : :: ::: ::: .: :.
CCDS95 VAVHELGHALGLEHSSDPSAIMAPFYQWMDTENFVLPDDDRRGIQQLYGGESGFPTKMPP
240 250 260 270 280 290
270 280 290 300 310 320
pF1KE2 EEEETELPTVPPVPTEPSPMPDPCSSELDAMMLGPRGKTYAFKGDYVWTVS-----DSGP
. . : :.:: : .:. :. :....:.. . ::. ..:: . : : :. :
CCDS95 QPRTTSRPSVPDKPKNPTYGPNICDGNFDTVAML-RGEMFVFKERWFWRVRNNQVMDGYP
300 310 320 330 340 350
330 340 350 360 370
pF1KE2 GPLFRVSALWEGLPGNLDAAVYSPRTQWIHFFKGDKVWRYINFKMSPGFPK---KLNRVE
: .. .:.:::.....: ... :::::: : . . .. ::.:: .:.:
CCDS95 MP---IGQFWRGLPASINTAYERKDGKFV-FFKGDKHWVFDEASLEPGYPKHIKELGRGL
360 370 380 390 400 410
380 390 400 410 420 430
pF1KE2 PN--LDAALYWPLNQKVFLFKGSGYWQWDELARTDFSSYPKPIKGLFTGVPNQPSAA-MS
:. .::::.: : :...:.:. :....: :. : ::: :: .. :.:..: .. :.
CCDS95 PTDKIDAALFWMPNGKTYFFRGNKYYRFNEELRAVDSEYPKNIK-VWEGIPESPRGSFMG
420 430 440 450 460
440 450 460 470 480 490
pF1KE2 WQDGRVYFFKGKVYWRLN-QQLRVEKGYPRNISHNWMHCRPRTIDTTPSGGNTTPSGTGI
.. .::.::. ::..: :.:.:: :::.. ..:: : ::::
CCDS95 SDEVFTYFYKGNKYWKFNNQKLKVEPGYPKSALRDWMGC--------PSGGRPDEGTEEE
470 480 490 500 510 520
500
pF1KE2 TLDTTLSATETTFEY
CCDS95 TEVIIIEVDEEGGGAVSAAAVVLPVLLLLLVLAVGLAVFFFRRHGTPRRLLYCQRSLLDK
530 540 550 560 570 580
>>CCDS76996.1 MMP28 gene_id:79148|Hs108|chr17 (393 aa)
initn: 649 init1: 310 opt: 614 Z-score: 628.0 bits: 125.4 E(32554): 1.2e-28
Smith-Waterman score: 726; 38.6% identity (60.6% similar) in 360 aa overlap (31-357:39-393)
10 20 30 40 50 60
pF1KE2 MNCQQLWLGFLLPMTVSGRVLGLAEVAPVDYLSQYGYLQKPLEGSNNFKPEDITEALRAF
.: .::::.. . . . ...:.:::
CCDS76 LRALQLLLWGHLDAQPAERGGQELRKEAEAFLEKYGYLNEQVPKAPT--STRFSDAIRAF
10 20 30 40 50 60
70 80 90 100
pF1KE2 QEASELPVSGQLDDATRARMRQPRCGLEDP-------------FNQKTLK------YLLL
: .:.::::: :: :: .: .::::. : : .. : .
CCDS76 QWVSQLPVSGVLDRATLRQMTRPRCGVTDTNSYAAWAERISDLFARHRTKMRRKKRFAKQ
70 80 90 100 110 120
110 120 130 140 150
pF1KE2 G-RWRKKHLTFRILNLPSTLPPHTARAALRQAFQDWSNVAPLTFQEVQA-GAADIRLSF-
: .: :.::..:..: : :: ..:.:.: ::: ::::. : : :. : : :::::.:
CCDS76 GNKWYKQHLSYRLVNWPEHLPEPAVRGAVRAAFQLWSNVSALEFWEAPATGPADIRLTFF
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE2 HGRQSSYCSNTFDGPGRVLAHADIPELGSVHFDEDEFWTEGTYRGVNLRIIAAHEVGHAL
.: ... .:.::::: .:::: .:. : .:::.:: :. . :: :: .. :::.::.:
CCDS76 QGDHNDGLGNAFDGPGGALAHAFLPRRGEAHFDQDERWSLSRRRGRNLFVVLAHEIGHTL
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE2 GLGHSRYSQALMAPVYEGYRPHFKLHPDDVAGIQALYGKK---SPVIRDEEEEETELPT-
:: :: .::::: :. : ::: ..:.:::: : ... . :.. :
CCDS76 GLTHSPAPRALMAPYYKRLGRDALLSWDDVLAVQSLYGKPLGGSVAVQLPGKLFTDFETW
250 260 270 280 290 300
280 290 300 310 320
pF1KE2 --VPPVPTEPSPM-PDPCSSELDAMMLGPRGKTYAFKGDYVWTVSDSG----PGPLFRVS
: .: . : : : .::. . . . : :::.. : :. .: : :: .
CCDS76 DSYSPQGRRPETQGPKYCHSSFDAITVDRQQQLYIFKGSHFWEVAADGNVSEPRPL---Q
310 320 330 340 350 360
330 340 350 360 370 380
pF1KE2 ALWEGLPGNLDAAVYSPRTQWIHFFKGDKVWRYINFKMSPGFPKKLNRVEPNLDAALYWP
: ::: :..::. : ..::: ..:
CCDS76 ERWVGLPPNIEAAAVSLNDGDFYFFKVQSV
370 380 390
508 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 05:18:48 2016 done: Tue Nov 8 05:18:49 2016
Total Scan time: 3.070 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]