Result of FASTA (omim) for
pFN21AE2264
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2264, 334 aa
1>>>pF1KE2264 334 - 334 aa - 334 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2320+/-0.000379; mu= 16.2729+/- 0.023
mean_var=68.8821+/-13.753, 0's: 0 Z-trim(112.5): 21 B-trim: 38 in 1/51
Lambda= 0.154533
statistics sampled from 21386 (21396) to 21386 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.632), E-opt: 0.2 (0.251), width: 16
Scan time: 6.900
The best scores are: opt bits E(85289)
NP_057393 (OMIM: 610286) leucine carboxyl methyltr ( 334) 2257 512.4 5.5e-145
XP_011544166 (OMIM: 610286) PREDICTED: leucine car ( 357) 2003 455.8 6.4e-128
XP_005255411 (OMIM: 610286) PREDICTED: leucine car ( 234) 1561 357.1 2.1e-98
NP_001027563 (OMIM: 610286) leucine carboxyl methy ( 279) 959 222.9 6.1e-58
XP_011544164 (OMIM: 610286) PREDICTED: leucine car ( 302) 959 223.0 6.5e-58
NP_055608 (OMIM: 611246) tRNA wybutosine-synthesiz ( 686) 618 147.2 9.8e-35
>>NP_057393 (OMIM: 610286) leucine carboxyl methyltransf (334 aa)
initn: 2257 init1: 2257 opt: 2257 Z-score: 2724.0 bits: 512.4 E(85289): 5.5e-145
Smith-Waterman score: 2257; 100.0% identity (100.0% similar) in 334 aa overlap (1-334:1-334)
10 20 30 40 50 60
pF1KE2 MATRQRESSITSCCSTSSCDADDEGVRGTCEDASLCKRFAVSIGYWHDPYIQHFVRLSKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MATRQRESSITSCCSTSSCDADDEGVRGTCEDASLCKRFAVSIGYWHDPYIQHFVRLSKE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 RKAPEINRGYFARVHGVSQLIKAFLRKTECHCQIVNLGAGMDTTFWRLKDEDLLPSKYFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 RKAPEINRGYFARVHGVSQLIKAFLRKTECHCQIVNLGAGMDTTFWRLKDEDLLPSKYFE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VDFPMIVTRKLHSIKCKPPLSSPILELHSEDTLQMDGHILDSKRYAVIGADLRDLSELEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 VDFPMIVTRKLHSIKCKPPLSSPILELHSEDTLQMDGHILDSKRYAVIGADLRDLSELEE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 KLKKCNMNTQLPTLLIAECVLVYMTPEQSANLLKWAANSFERAMFINYEQVNMGDRFGQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 KLKKCNMNTQLPTLLIAECVLVYMTPEQSANLLKWAANSFERAMFINYEQVNMGDRFGQI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 MIENLRRRQCDLAGVETCKSLESQKERLLSNGWETASAVDMMELYNRLPRAEVSRIESLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MIENLRRRQCDLAGVETCKSLESQKERLLSNGWETASAVDMMELYNRLPRAEVSRIESLE
250 260 270 280 290 300
310 320 330
pF1KE2 FLDEMELLEQLMRHYCLCWATKGGNELGLKEITY
::::::::::::::::::::::::::::::::::
NP_057 FLDEMELLEQLMRHYCLCWATKGGNELGLKEITY
310 320 330
>>XP_011544166 (OMIM: 610286) PREDICTED: leucine carboxy (357 aa)
initn: 2023 init1: 2003 opt: 2003 Z-score: 2417.5 bits: 455.8 E(85289): 6.4e-128
Smith-Waterman score: 2003; 99.7% identity (100.0% similar) in 298 aa overlap (37-334:60-357)
10 20 30 40 50 60
pF1KE2 ESSITSCCSTSSCDADDEGVRGTCEDASLCKRFAVSIGYWHDPYIQHFVRLSKERKAPEI
.:::::::::::::::::::::::::::::
XP_011 ILATLIGWTVRSFFLGRMETCCSHLGLRSGRRFAVSIGYWHDPYIQHFVRLSKERKAPEI
30 40 50 60 70 80
70 80 90 100 110 120
pF1KE2 NRGYFARVHGVSQLIKAFLRKTECHCQIVNLGAGMDTTFWRLKDEDLLPSKYFEVDFPMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRGYFARVHGVSQLIKAFLRKTECHCQIVNLGAGMDTTFWRLKDEDLLPSKYFEVDFPMI
90 100 110 120 130 140
130 140 150 160 170 180
pF1KE2 VTRKLHSIKCKPPLSSPILELHSEDTLQMDGHILDSKRYAVIGADLRDLSELEEKLKKCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTRKLHSIKCKPPLSSPILELHSEDTLQMDGHILDSKRYAVIGADLRDLSELEEKLKKCN
150 160 170 180 190 200
190 200 210 220 230 240
pF1KE2 MNTQLPTLLIAECVLVYMTPEQSANLLKWAANSFERAMFINYEQVNMGDRFGQIMIENLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNTQLPTLLIAECVLVYMTPEQSANLLKWAANSFERAMFINYEQVNMGDRFGQIMIENLR
210 220 230 240 250 260
250 260 270 280 290 300
pF1KE2 RRQCDLAGVETCKSLESQKERLLSNGWETASAVDMMELYNRLPRAEVSRIESLEFLDEME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRQCDLAGVETCKSLESQKERLLSNGWETASAVDMMELYNRLPRAEVSRIESLEFLDEME
270 280 290 300 310 320
310 320 330
pF1KE2 LLEQLMRHYCLCWATKGGNELGLKEITY
::::::::::::::::::::::::::::
XP_011 LLEQLMRHYCLCWATKGGNELGLKEITY
330 340 350
>>XP_005255411 (OMIM: 610286) PREDICTED: leucine carboxy (234 aa)
initn: 1561 init1: 1561 opt: 1561 Z-score: 1887.6 bits: 357.1 E(85289): 2.1e-98
Smith-Waterman score: 1561; 100.0% identity (100.0% similar) in 234 aa overlap (101-334:1-234)
80 90 100 110 120 130
pF1KE2 FARVHGVSQLIKAFLRKTECHCQIVNLGAGMDTTFWRLKDEDLLPSKYFEVDFPMIVTRK
::::::::::::::::::::::::::::::
XP_005 MDTTFWRLKDEDLLPSKYFEVDFPMIVTRK
10 20 30
140 150 160 170 180 190
pF1KE2 LHSIKCKPPLSSPILELHSEDTLQMDGHILDSKRYAVIGADLRDLSELEEKLKKCNMNTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LHSIKCKPPLSSPILELHSEDTLQMDGHILDSKRYAVIGADLRDLSELEEKLKKCNMNTQ
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE2 LPTLLIAECVLVYMTPEQSANLLKWAANSFERAMFINYEQVNMGDRFGQIMIENLRRRQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPTLLIAECVLVYMTPEQSANLLKWAANSFERAMFINYEQVNMGDRFGQIMIENLRRRQC
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE2 DLAGVETCKSLESQKERLLSNGWETASAVDMMELYNRLPRAEVSRIESLEFLDEMELLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLAGVETCKSLESQKERLLSNGWETASAVDMMELYNRLPRAEVSRIESLEFLDEMELLEQ
160 170 180 190 200 210
320 330
pF1KE2 LMRHYCLCWATKGGNELGLKEITY
::::::::::::::::::::::::
XP_005 LMRHYCLCWATKGGNELGLKEITY
220 230
>>NP_001027563 (OMIM: 610286) leucine carboxyl methyltra (279 aa)
initn: 959 init1: 959 opt: 959 Z-score: 1161.2 bits: 222.9 E(85289): 6.1e-58
Smith-Waterman score: 1771; 83.5% identity (83.5% similar) in 334 aa overlap (1-334:1-279)
10 20 30 40 50 60
pF1KE2 MATRQRESSITSCCSTSSCDADDEGVRGTCEDASLCKRFAVSIGYWHDPYIQHFVRLSKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MATRQRESSITSCCSTSSCDADDEGVRGTCEDASLCKRFAVSIGYWHDPYIQHFVRLSKE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 RKAPEINRGYFARVHGVSQLIKAFLRKTECHCQIVNLGAGMDTTFWRLKDEDLLPSKYFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKAPEINRGYFARVHGVSQLIKAFLRKTECHCQIVNLGAGMDTTFWRLKDEDLLPSKYFE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VDFPMIVTRKLHSIKCKPPLSSPILELHSEDTLQMDGHILDSKRYAVIGADLRDLSELEE
:::::::::::::::
NP_001 VDFPMIVTRKLHSIK---------------------------------------------
130
190 200 210 220 230 240
pF1KE2 KLKKCNMNTQLPTLLIAECVLVYMTPEQSANLLKWAANSFERAMFINYEQVNMGDRFGQI
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ----------LPTLLIAECVLVYMTPEQSANLLKWAANSFERAMFINYEQVNMGDRFGQI
140 150 160 170 180
250 260 270 280 290 300
pF1KE2 MIENLRRRQCDLAGVETCKSLESQKERLLSNGWETASAVDMMELYNRLPRAEVSRIESLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIENLRRRQCDLAGVETCKSLESQKERLLSNGWETASAVDMMELYNRLPRAEVSRIESLE
190 200 210 220 230 240
310 320 330
pF1KE2 FLDEMELLEQLMRHYCLCWATKGGNELGLKEITY
::::::::::::::::::::::::::::::::::
NP_001 FLDEMELLEQLMRHYCLCWATKGGNELGLKEITY
250 260 270
>>XP_011544164 (OMIM: 610286) PREDICTED: leucine carboxy (302 aa)
initn: 979 init1: 959 opt: 959 Z-score: 1160.7 bits: 223.0 E(85289): 6.5e-58
Smith-Waterman score: 1517; 81.2% identity (81.5% similar) in 298 aa overlap (37-334:60-302)
10 20 30 40 50 60
pF1KE2 ESSITSCCSTSSCDADDEGVRGTCEDASLCKRFAVSIGYWHDPYIQHFVRLSKERKAPEI
.:::::::::::::::::::::::::::::
XP_011 ILATLIGWTVRSFFLGRMETCCSHLGLRSGRRFAVSIGYWHDPYIQHFVRLSKERKAPEI
30 40 50 60 70 80
70 80 90 100 110 120
pF1KE2 NRGYFARVHGVSQLIKAFLRKTECHCQIVNLGAGMDTTFWRLKDEDLLPSKYFEVDFPMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRGYFARVHGVSQLIKAFLRKTECHCQIVNLGAGMDTTFWRLKDEDLLPSKYFEVDFPMI
90 100 110 120 130 140
130 140 150 160 170 180
pF1KE2 VTRKLHSIKCKPPLSSPILELHSEDTLQMDGHILDSKRYAVIGADLRDLSELEEKLKKCN
:::::::::
XP_011 VTRKLHSIK---------------------------------------------------
150
190 200 210 220 230 240
pF1KE2 MNTQLPTLLIAECVLVYMTPEQSANLLKWAANSFERAMFINYEQVNMGDRFGQIMIENLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ----LPTLLIAECVLVYMTPEQSANLLKWAANSFERAMFINYEQVNMGDRFGQIMIENLR
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE2 RRQCDLAGVETCKSLESQKERLLSNGWETASAVDMMELYNRLPRAEVSRIESLEFLDEME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRQCDLAGVETCKSLESQKERLLSNGWETASAVDMMELYNRLPRAEVSRIESLEFLDEME
220 230 240 250 260 270
310 320 330
pF1KE2 LLEQLMRHYCLCWATKGGNELGLKEITY
::::::::::::::::::::::::::::
XP_011 LLEQLMRHYCLCWATKGGNELGLKEITY
280 290 300
>>NP_055608 (OMIM: 611246) tRNA wybutosine-synthesizing (686 aa)
initn: 529 init1: 339 opt: 618 Z-score: 744.6 bits: 147.2 E(85289): 9.8e-35
Smith-Waterman score: 618; 36.4% identity (65.9% similar) in 305 aa overlap (26-323:13-314)
10 20 30 40 50 60
pF1KE2 MATRQRESSITSCCSTSSCDADDEGVRGTCEDASLCKRFAVSIGYWHDPYIQHFVRLSKE
:..: ....: :: .. :: .::. .: .
NP_055 MGPRSRERRAGAVQNTNDSSALSKRSLAARGYVQDPFAALLVP-GAA
10 20 30 40
70 80 90 100 110
pF1KE2 RKAPEINRGYFARVHGVSQLIKAFLRK-----TECHCQIVNLGAGMDTTFWRLKDEDLLP
:.:: :.:::..:...: . ..:::.. . . ::..::::.:. ..::: :
NP_055 RRAPLIHRGYYVRARAVRHCVRAFLEQIGAPQAALRAQILSLGAGFDSLYFRLKTAGRLA
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE2 -SKYFEVDFPMIVTRKLHSIKCKPPLSSPILELHSEDTLQMDGHILDSKRYAVIGADLRD
. .::::: .. :: . : : : . : : .. ..: : ..: :::.
NP_055 RAAVWEVDFPDVARRKAERIGETPELCA--LTGPFERGEPASALCFESADYCILGLDLRQ
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE2 LSELEEKLKKCNMNTQLPTLLIAECVLVYMTPEQSANLLKWAANSFERAMFINYEQVNMG
:...:: : .... ::::.:: ::.:. ::..: :. :::. : :.:. :::.
NP_055 LQRVEEALGAAGLDAASPTLLLAEAVLTYLEPESAAALIAWAAQRFPNALFVVYEQMRPQ
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE2 DRFGQIMIENLRRRQCDLAGVETCKSLESQKERLLSNGWETASAVDMMELYN-RLPRAEV
: :::.:....:. . : :.: ..:.:..:.:. :: . .:::: :.:. :: :
NP_055 DAFGQFMLQHFRQLNSPLHGLERFPDVEAQRRRFLQAGWTACGAVDMNEFYHCFLPAEER
230 240 250 260 270 280
300 310 320 330
pF1KE2 SRIESLEFLDEMELLEQLMRHYCLCWATKGGNELGLKEITY
:.:..: .::.: . :: . :..:
NP_055 RRVENIEPFDEFEEWHLKCAHYFILAASRGDTLSHTLVFPSSEAFPRVNPASPSGVFPAS
290 300 310 320 330 340
334 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 05:06:01 2016 done: Sun Nov 6 05:06:03 2016
Total Scan time: 6.900 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]