Result of FASTA (omim) for
pFN21AE2255
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2255, 374 aa
1>>>pF1KE2255 374 - 374 aa - 374 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7435+/-0.000379; mu= 19.8277+/- 0.024
mean_var=118.4318+/-30.291, 0's: 0 Z-trim(113.6): 534 B-trim: 1258 in 1/56
Lambda= 0.117853
statistics sampled from 22280 (22988) to 22280 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.632), E-opt: 0.2 (0.27), width: 16
Scan time: 7.430
The best scores are: opt bits E(85289)
NP_871001 (OMIM: 609043) relaxin-3 receptor 2 [Hom ( 374) 2516 439.5 6.1e-123
NP_000676 (OMIM: 106165,145500,267430) type-1 angi ( 359) 510 98.4 2.8e-20
NP_033611 (OMIM: 106165,145500,267430) type-1 angi ( 359) 510 98.4 2.8e-20
NP_114438 (OMIM: 106165,145500,267430) type-1 angi ( 388) 510 98.4 2.9e-20
NP_004826 (OMIM: 106165,145500,267430) type-1 angi ( 394) 510 98.4 3e-20
NP_114038 (OMIM: 106165,145500,267430) type-1 angi ( 394) 510 98.4 3e-20
XP_011535835 (OMIM: 300034) PREDICTED: type-2 angi ( 363) 494 95.6 1.9e-19
NP_000677 (OMIM: 300034) type-2 angiotensin II rec ( 363) 494 95.6 1.9e-19
NP_001043 (OMIM: 182454) somatostatin receptor typ ( 388) 490 95.0 3.1e-19
NP_000902 (OMIM: 165195) delta-type opioid recepto ( 372) 482 93.6 7.8e-19
XP_005246154 (OMIM: 610376) PREDICTED: atypical ch ( 362) 473 92.1 2.2e-18
XP_005246155 (OMIM: 610376) PREDICTED: atypical ch ( 362) 473 92.1 2.2e-18
NP_064707 (OMIM: 610376) atypical chemokine recept ( 362) 473 92.1 2.2e-18
XP_016860005 (OMIM: 610376) PREDICTED: atypical ch ( 362) 473 92.1 2.2e-18
NP_005276 (OMIM: 600730) neuropeptides B/W recepto ( 328) 467 91.0 4.3e-18
NP_001186948 (OMIM: 602548) nociceptin receptor is ( 370) 455 89.0 1.9e-17
NP_872588 (OMIM: 602548) nociceptin receptor isofo ( 370) 455 89.0 1.9e-17
NP_000904 (OMIM: 602548) nociceptin receptor isofo ( 370) 455 89.0 1.9e-17
XP_016883343 (OMIM: 602548) PREDICTED: nociceptin ( 370) 455 89.0 1.9e-17
XP_016883341 (OMIM: 602548) PREDICTED: nociceptin ( 388) 455 89.1 1.9e-17
XP_016883342 (OMIM: 602548) PREDICTED: nociceptin ( 388) 455 89.1 1.9e-17
XP_011527130 (OMIM: 602548) PREDICTED: nociceptin ( 388) 455 89.1 1.9e-17
NP_001305782 (OMIM: 602548) nociceptin receptor is ( 399) 455 89.1 2e-17
NP_001044 (OMIM: 182455) somatostatin receptor typ ( 364) 453 88.7 2.4e-17
NP_001166031 (OMIM: 182455) somatostatin receptor ( 364) 453 88.7 2.4e-17
NP_001138757 (OMIM: 600018) mu-type opioid recepto ( 389) 451 88.4 3.1e-17
NP_001008504 (OMIM: 600018) mu-type opioid recepto ( 392) 451 88.4 3.1e-17
NP_001138755 (OMIM: 600018) mu-type opioid recepto ( 397) 451 88.4 3.1e-17
NP_000905 (OMIM: 600018) mu-type opioid receptor i ( 400) 451 88.4 3.1e-17
NP_001138756 (OMIM: 600018) mu-type opioid recepto ( 403) 451 88.4 3.2e-17
NP_001138754 (OMIM: 600018) mu-type opioid recepto ( 406) 451 88.4 3.2e-17
NP_001272452 (OMIM: 600018) mu-type opioid recepto ( 414) 451 88.4 3.2e-17
NP_001008503 (OMIM: 600018) mu-type opioid recepto ( 418) 451 88.4 3.2e-17
NP_001138758 (OMIM: 600018) mu-type opioid recepto ( 420) 451 88.4 3.2e-17
NP_001008505 (OMIM: 600018) mu-type opioid recepto ( 446) 451 88.5 3.3e-17
NP_001138751 (OMIM: 600018) mu-type opioid recepto ( 493) 451 88.5 3.5e-17
NP_001272453 (OMIM: 600018) mu-type opioid recepto ( 493) 451 88.5 3.5e-17
NP_003458 (OMIM: 162643,193670) C-X-C chemokine re ( 352) 447 87.6 4.7e-17
NP_001008540 (OMIM: 162643,193670) C-X-C chemokine ( 356) 447 87.6 4.7e-17
NP_005289 (OMIM: 602174) probable G-protein couple ( 361) 447 87.6 4.7e-17
XP_016884412 (OMIM: 182453) PREDICTED: somatostati ( 418) 445 87.4 6.5e-17
XP_011528651 (OMIM: 182453) PREDICTED: somatostati ( 418) 445 87.4 6.5e-17
NP_001042 (OMIM: 182453) somatostatin receptor typ ( 418) 445 87.4 6.5e-17
XP_005261778 (OMIM: 182453) PREDICTED: somatostati ( 418) 445 87.4 6.5e-17
XP_006724374 (OMIM: 182453) PREDICTED: somatostati ( 418) 445 87.4 6.5e-17
NP_001265616 (OMIM: 182453) somatostatin receptor ( 418) 445 87.4 6.5e-17
XP_016884413 (OMIM: 182453) PREDICTED: somatostati ( 418) 445 87.4 6.5e-17
NP_001305783 (OMIM: 602548) nociceptin receptor is ( 365) 441 86.6 9.7e-17
XP_016883344 (OMIM: 602548) PREDICTED: nociceptin ( 365) 441 86.6 9.7e-17
NP_006632 (OMIM: 604738) C-C chemokine receptor ty ( 357) 433 85.3 2.5e-16
>>NP_871001 (OMIM: 609043) relaxin-3 receptor 2 [Homo sa (374 aa)
initn: 2516 init1: 2516 opt: 2516 Z-score: 2328.1 bits: 439.5 E(85289): 6.1e-123
Smith-Waterman score: 2516; 99.7% identity (99.7% similar) in 374 aa overlap (1-374:1-374)
10 20 30 40 50 60
pF1KE2 MPTLNTSASPPTFFWANASGGSVLSADDAPMPVKFLALRLMVALAYGLVGAIGLLGNLAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_871 MPTLNTSASPPTFFWANASGGSVLSADDAPMPVKFLALRLMVALAYGLVGAIGLLGNLAV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LWVLSNCARRAPGPPSDTFVFNLALADLGLALTLPFWAAESALDFHWPFGGALCKMVLTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_871 LWVLSNCARRAPGPPSDTFVFNLALADLGLALTLPFWAAESALDFHWPFGGALCKMVLTA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 TVLNVYASIFLITALSVARYWVVAMAAGPGTHLSLFWARIATLAVWAAAALVTVPTAVFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_871 TVLNVYASIFLITALSVARYWVVAMAAGPGTHLSLFWARIATLAVWAAAALVTVPTAVFG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 VEGEVCGVRLCLLRFPSRYWLGAYQLQRVVLAFMVPLGVITTSYLLLLAFLQRRQRRRQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_871 VEGEVCGVRLCLLRFPSRYWLGAYQLQRVVLAFMVPLGVITTSYLLLLAFLQRRQRRRQD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SRVVARSVRILVASFFLCWFPNHVVTLWGVLVKFDLVPWNSTFYTIQTYVFPVTTCLAHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_871 SRVVARSVRILVASFFLCWFPNHVVTLWGVLVKFDLVPWNSTFYTIQTYVFPVTTCLAHS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 NSCLNPVLYCLLRREPRQALAGTFRDLRSRLWPQGGGWVQQVALKQVGRRWVASNPRESR
:::::::::::::::::::::::::::: :::::::::::::::::::::::::::::::
NP_871 NSCLNPVLYCLLRREPRQALAGTFRDLRLRLWPQGGGWVQQVALKQVGRRWVASNPRESR
310 320 330 340 350 360
370
pF1KE2 PSTLLTNLDRGTPG
::::::::::::::
NP_871 PSTLLTNLDRGTPG
370
>>NP_000676 (OMIM: 106165,145500,267430) type-1 angioten (359 aa)
initn: 271 init1: 236 opt: 510 Z-score: 485.0 bits: 98.4 E(85289): 2.8e-20
Smith-Waterman score: 510; 28.4% identity (63.5% similar) in 299 aa overlap (27-315:16-308)
10 20 30 40 50 60
pF1KE2 MPTLNTSASPPTFFWANASGGSVLSADDAPMPVKFLALRLMVALAYGLVGAIGLLGNLAV
:: : . . .:. :... ..:..:: :
NP_000 MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLV
10 20 30 40
70 80 90 100 110 120
pF1KE2 LWVLSNCARRAPGPPSDTFVFNLALADLGLALTLPFWAAESALDFHWPFGGALCKMVLTA
. :. . ...:..::::::: . ::::.::. .:....::::. :::.. ..
NP_000 VIVIYFYMKLK--TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASAS
50 60 70 80 90 100
130 140 150 160 170
pF1KE2 TVLNVYASIFLITALSVARYWVVAMAAGPGTHLSLFWARIATLAVWAAAALVTVPTA---
. .:.:::.::.: ::. :: ... . ... :... . .: :.:...:.
NP_000 VSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHR
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE2 -VFGVEGEVCGVRLCLLRFPSR---YWLGAYQLQRVVLAFMVPLGVITTSYLLLLAFLQR
:: .:. .. .: ... :. .: : . .:.:. :. .: ::: :. :..
NP_000 NVFFIEN--TNITVCAFHYESQNSTLPIG-LGLTKNILGFLFPFLIILTSYTLIWKALKK
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE2 R---QRRRQDSRVVARSVRILVASFFLCWFPNHVVTLWGVLVKFDLVPWNSTFYTIQTYV
:. . . . . . .: ::. :.:... :. ::... .. . . : .
NP_000 AYEIQKNKPRNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIR-DCRIADIVDTA
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE2 FPVTTCLAHSNSCLNPVLYCLLRREPRQALAGTFRDLRSRLWPQGGGWVQQVALKQVGRR
.:.: :.:. :.::::..: .: ..
NP_000 MPITICIAYFNNCLNPLFYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSD
290 300 310 320 330 340
>>NP_033611 (OMIM: 106165,145500,267430) type-1 angioten (359 aa)
initn: 271 init1: 236 opt: 510 Z-score: 485.0 bits: 98.4 E(85289): 2.8e-20
Smith-Waterman score: 510; 28.4% identity (63.5% similar) in 299 aa overlap (27-315:16-308)
10 20 30 40 50 60
pF1KE2 MPTLNTSASPPTFFWANASGGSVLSADDAPMPVKFLALRLMVALAYGLVGAIGLLGNLAV
:: : . . .:. :... ..:..:: :
NP_033 MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLV
10 20 30 40
70 80 90 100 110 120
pF1KE2 LWVLSNCARRAPGPPSDTFVFNLALADLGLALTLPFWAAESALDFHWPFGGALCKMVLTA
. :. . ...:..::::::: . ::::.::. .:....::::. :::.. ..
NP_033 VIVIYFYMKLK--TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASAS
50 60 70 80 90 100
130 140 150 160 170
pF1KE2 TVLNVYASIFLITALSVARYWVVAMAAGPGTHLSLFWARIATLAVWAAAALVTVPTA---
. .:.:::.::.: ::. :: ... . ... :... . .: :.:...:.
NP_033 VSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHR
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE2 -VFGVEGEVCGVRLCLLRFPSR---YWLGAYQLQRVVLAFMVPLGVITTSYLLLLAFLQR
:: .:. .. .: ... :. .: : . .:.:. :. .: ::: :. :..
NP_033 NVFFIEN--TNITVCAFHYESQNSTLPIG-LGLTKNILGFLFPFLIILTSYTLIWKALKK
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE2 R---QRRRQDSRVVARSVRILVASFFLCWFPNHVVTLWGVLVKFDLVPWNSTFYTIQTYV
:. . . . . . .: ::. :.:... :. ::... .. . . : .
NP_033 AYEIQKNKPRNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIR-DCRIADIVDTA
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE2 FPVTTCLAHSNSCLNPVLYCLLRREPRQALAGTFRDLRSRLWPQGGGWVQQVALKQVGRR
.:.: :.:. :.::::..: .: ..
NP_033 MPITICIAYFNNCLNPLFYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSD
290 300 310 320 330 340
>>NP_114438 (OMIM: 106165,145500,267430) type-1 angioten (388 aa)
initn: 271 init1: 236 opt: 510 Z-score: 484.7 bits: 98.4 E(85289): 2.9e-20
Smith-Waterman score: 510; 28.4% identity (63.5% similar) in 299 aa overlap (27-315:45-337)
10 20 30 40 50
pF1KE2 MPTLNTSASPPTFFWANASGGSVLSADDAPMPVKFLALRLMVALAYGLVGAIGLLG
:: : . . .:. :... ..:..:
NP_114 VFDIVFATNSTQVIKMILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFG
20 30 40 50 60 70
60 70 80 90 100 110
pF1KE2 NLAVLWVLSNCARRAPGPPSDTFVFNLALADLGLALTLPFWAAESALDFHWPFGGALCKM
: :. :. . ...:..::::::: . ::::.::. .:....::::. :::.
NP_114 NSLVVIVIYFYMKLK--TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKI
80 90 100 110 120 130
120 130 140 150 160 170
pF1KE2 VLTATVLNVYASIFLITALSVARYWVVAMAAGPGTHLSLFWARIATLAVWAAAALVTVPT
. ... .:.:::.::.: ::. :: ... . ... :... . .: :.:...:.
NP_114 ASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPA
140 150 160 170 180 190
180 190 200 210 220
pF1KE2 A----VFGVEGEVCGVRLCLLRFPSR---YWLGAYQLQRVVLAFMVPLGVITTSYLLLLA
:: .:. .. .: ... :. .: : . .:.:. :. .: ::: :.
NP_114 IIHRNVFFIEN--TNITVCAFHYESQNSTLPIG-LGLTKNILGFLFPFLIILTSYTLIWK
200 210 220 230 240
230 240 250 260 270 280
pF1KE2 FLQRR---QRRRQDSRVVARSVRILVASFFLCWFPNHVVTLWGVLVKFDLVPWNSTFYTI
:.. :. . . . . . .: ::. :.:... :. ::... .. . . :
NP_114 ALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIR-DCRIADI
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE2 QTYVFPVTTCLAHSNSCLNPVLYCLLRREPRQALAGTFRDLRSRLWPQGGGWVQQVALKQ
..:.: :.:. :.::::..: .: ..
NP_114 VDTAMPITICIAYFNNCLNPLFYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSY
310 320 330 340 350 360
>>NP_004826 (OMIM: 106165,145500,267430) type-1 angioten (394 aa)
initn: 271 init1: 236 opt: 510 Z-score: 484.6 bits: 98.4 E(85289): 3e-20
Smith-Waterman score: 510; 28.4% identity (63.5% similar) in 299 aa overlap (27-315:51-343)
10 20 30 40 50
pF1KE2 MPTLNTSASPPTFFWANASGGSVLSADDAPMPVKFLALRLMVALAYGLVGAIGLLG
:: : . . .:. :... ..:..:
NP_004 VFDIVFATNSTQVIKMILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFG
30 40 50 60 70 80
60 70 80 90 100 110
pF1KE2 NLAVLWVLSNCARRAPGPPSDTFVFNLALADLGLALTLPFWAAESALDFHWPFGGALCKM
: :. :. . ...:..::::::: . ::::.::. .:....::::. :::.
NP_004 NSLVVIVIYFYMKLK--TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKI
90 100 110 120 130
120 130 140 150 160 170
pF1KE2 VLTATVLNVYASIFLITALSVARYWVVAMAAGPGTHLSLFWARIATLAVWAAAALVTVPT
. ... .:.:::.::.: ::. :: ... . ... :... . .: :.:...:.
NP_004 ASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPA
140 150 160 170 180 190
180 190 200 210 220
pF1KE2 A----VFGVEGEVCGVRLCLLRFPSR---YWLGAYQLQRVVLAFMVPLGVITTSYLLLLA
:: .:. .. .: ... :. .: : . .:.:. :. .: ::: :.
NP_004 IIHRNVFFIEN--TNITVCAFHYESQNSTLPIG-LGLTKNILGFLFPFLIILTSYTLIWK
200 210 220 230 240 250
230 240 250 260 270 280
pF1KE2 FLQRR---QRRRQDSRVVARSVRILVASFFLCWFPNHVVTLWGVLVKFDLVPWNSTFYTI
:.. :. . . . . . .: ::. :.:... :. ::... .. . . :
NP_004 ALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIR-DCRIADI
260 270 280 290 300 310
290 300 310 320 330 340
pF1KE2 QTYVFPVTTCLAHSNSCLNPVLYCLLRREPRQALAGTFRDLRSRLWPQGGGWVQQVALKQ
..:.: :.:. :.::::..: .: ..
NP_004 VDTAMPITICIAYFNNCLNPLFYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSY
320 330 340 350 360 370
>>NP_114038 (OMIM: 106165,145500,267430) type-1 angioten (394 aa)
initn: 271 init1: 236 opt: 510 Z-score: 484.6 bits: 98.4 E(85289): 3e-20
Smith-Waterman score: 510; 28.4% identity (63.5% similar) in 299 aa overlap (27-315:51-343)
10 20 30 40 50
pF1KE2 MPTLNTSASPPTFFWANASGGSVLSADDAPMPVKFLALRLMVALAYGLVGAIGLLG
:: : . . .:. :... ..:..:
NP_114 VFDIVFATNSTQVIKMILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFG
30 40 50 60 70 80
60 70 80 90 100 110
pF1KE2 NLAVLWVLSNCARRAPGPPSDTFVFNLALADLGLALTLPFWAAESALDFHWPFGGALCKM
: :. :. . ...:..::::::: . ::::.::. .:....::::. :::.
NP_114 NSLVVIVIYFYMKLK--TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKI
90 100 110 120 130
120 130 140 150 160 170
pF1KE2 VLTATVLNVYASIFLITALSVARYWVVAMAAGPGTHLSLFWARIATLAVWAAAALVTVPT
. ... .:.:::.::.: ::. :: ... . ... :... . .: :.:...:.
NP_114 ASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPA
140 150 160 170 180 190
180 190 200 210 220
pF1KE2 A----VFGVEGEVCGVRLCLLRFPSR---YWLGAYQLQRVVLAFMVPLGVITTSYLLLLA
:: .:. .. .: ... :. .: : . .:.:. :. .: ::: :.
NP_114 IIHRNVFFIEN--TNITVCAFHYESQNSTLPIG-LGLTKNILGFLFPFLIILTSYTLIWK
200 210 220 230 240 250
230 240 250 260 270 280
pF1KE2 FLQRR---QRRRQDSRVVARSVRILVASFFLCWFPNHVVTLWGVLVKFDLVPWNSTFYTI
:.. :. . . . . . .: ::. :.:... :. ::... .. . . :
NP_114 ALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIR-DCRIADI
260 270 280 290 300 310
290 300 310 320 330 340
pF1KE2 QTYVFPVTTCLAHSNSCLNPVLYCLLRREPRQALAGTFRDLRSRLWPQGGGWVQQVALKQ
..:.: :.:. :.::::..: .: ..
NP_114 VDTAMPITICIAYFNNCLNPLFYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSY
320 330 340 350 360 370
>>XP_011535835 (OMIM: 300034) PREDICTED: type-2 angioten (363 aa)
initn: 396 init1: 198 opt: 494 Z-score: 470.2 bits: 95.6 E(85289): 1.9e-19
Smith-Waterman score: 494; 31.4% identity (59.0% similar) in 334 aa overlap (13-335:20-342)
10 20 30 40 50
pF1KE2 MPTLNTSASPPTFFWANASGG--SVLSADDAPMPVKFLALRLMVALAYGLVGA
: .: ::. :.:. .. : .. :. .. : .. .
XP_011 MKGNSTLATTSKNITSGLHFGLVNISGNNESTLNCSQKPSDKHLDAIPIL----YYIIFV
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 IGLLGNLAVLWVLSNCARRAPGPPSDTFVFNLALADLGLALTLPFWAAESALDFHWPFGG
::.: :..:. .. : ...: :. ..::::.::: : :::.::. . . : ::
XP_011 IGFLVNIVVVTLF--CCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGP
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 ALCKMVLTATVLNVYASIFLITALSVARYWVVAMAAGPGTHLSLFWARIATLAVWAAAAL
..::. . .::..::::.:: .:: :: : . . . :. : :: : :
XP_011 VMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPL-VWCMACL
120 130 140 150 160 170
180 190 200 210 220
pF1KE2 VTVPTAVF-GVEG-EVCGVRLCLLRFPS-RY--WLGAYQLQRVVLAFMVPLGVITTSYLL
..:: : :. : :: :.. :: .: : .. :.. .:.:..:: :.: :.
XP_011 SSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFG
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE2 LLAFLQRRQ---RRRQDSRVVARSVRILVASFFLCWFPNHVVTLWGVLVKFDLVPWNST-
. : . . . : : . . .: .:..::.: ::.:. .:. . .. ::
XP_011 IRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVI--NSCE
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE2 FYTIQTYVFPVTTCLAHSNSCLNPVLYCLLRREPRQALAGTFRDLRSRLWPQGGGWVQQV
.. ..: . :. .:::.:: :::.. . .: : ..:: : ::
XP_011 VIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFR--VPITWLQGKRESMSC
300 310 320 330 340
350 360 370
pF1KE2 ALKQVGRRWVASNPRESRPSTLLTNLDRGTPG
XP_011 RKSSSLREMETFVS
350 360
>>NP_000677 (OMIM: 300034) type-2 angiotensin II recepto (363 aa)
initn: 396 init1: 198 opt: 494 Z-score: 470.2 bits: 95.6 E(85289): 1.9e-19
Smith-Waterman score: 494; 31.4% identity (59.0% similar) in 334 aa overlap (13-335:20-342)
10 20 30 40 50
pF1KE2 MPTLNTSASPPTFFWANASGG--SVLSADDAPMPVKFLALRLMVALAYGLVGA
: .: ::. :.:. .. : .. :. .. : .. .
NP_000 MKGNSTLATTSKNITSGLHFGLVNISGNNESTLNCSQKPSDKHLDAIPIL----YYIIFV
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 IGLLGNLAVLWVLSNCARRAPGPPSDTFVFNLALADLGLALTLPFWAAESALDFHWPFGG
::.: :..:. .. : ...: :. ..::::.::: : :::.::. . . : ::
NP_000 IGFLVNIVVVTLF--CCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGP
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 ALCKMVLTATVLNVYASIFLITALSVARYWVVAMAAGPGTHLSLFWARIATLAVWAAAAL
..::. . .::..::::.:: .:: :: : . . . :. : :: : :
NP_000 VMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPL-VWCMACL
120 130 140 150 160 170
180 190 200 210 220
pF1KE2 VTVPTAVF-GVEG-EVCGVRLCLLRFPS-RY--WLGAYQLQRVVLAFMVPLGVITTSYLL
..:: : :. : :: :.. :: .: : .. :.. .:.:..:: :.: :.
NP_000 SSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFG
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE2 LLAFLQRRQ---RRRQDSRVVARSVRILVASFFLCWFPNHVVTLWGVLVKFDLVPWNST-
. : . . . : : . . .: .:..::.: ::.:. .:. . .. ::
NP_000 IRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVI--NSCE
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE2 FYTIQTYVFPVTTCLAHSNSCLNPVLYCLLRREPRQALAGTFRDLRSRLWPQGGGWVQQV
.. ..: . :. .:::.:: :::.. . .: : ..:: : ::
NP_000 VIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFR--VPITWLQGKRESMSC
300 310 320 330 340
350 360 370
pF1KE2 ALKQVGRRWVASNPRESRPSTLLTNLDRGTPG
NP_000 RKSSSLREMETFVS
350 360
>>NP_001043 (OMIM: 182454) somatostatin receptor type 4 (388 aa)
initn: 418 init1: 216 opt: 490 Z-score: 466.3 bits: 95.0 E(85289): 3.1e-19
Smith-Waterman score: 490; 32.2% identity (61.1% similar) in 332 aa overlap (16-337:23-338)
10 20 30 40 50
pF1KE2 MPTLNTSASPPTFFWANASGGSVLSADDAPMPVKFLALRLMVALA--YGLVGA
::::.. . . . . : : :::. :.::
NP_001 MSAPSTLPPGGEEGLGTAWPSAANASSAPAEAEEAVAGPGDARAAG-MVAIQCIYALVCL
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 IGLLGNLAVLWVLSNCARRAPGPPSDTFVFNLALADLGLALTLPFWAAESALDFHWPFGG
.::.:: :..:. :. . .. ...:::.:: . :..:: :. .:: :::::.
NP_001 VGLVGNALVIFVILRYAKMKTA--TNIYLLNLAVADELFMLSVPFVASSAALR-HWPFGS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 ALCKMVLTATVLNVYASIFLITALSVARYWVVAMAAGPGTHLSLFWARIATLAVWAAAAL
.::. ::.. ::...:.: .:.::: :: .:. .:. :.. .:.:: :. :
NP_001 VLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLL
120 130 140 150 160 170
180 190 200 210 220
pF1KE2 VTVPTAVFGVEGEVCGVRL--CLLRFPSRYWLGAYQLQRVVLAFMVPLGVITTSYLLLL-
::.: :.:. . : . : :..: : ... . .:.:..:. .: :::..
NP_001 VTLPIAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAIGLCYLLIVG
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE2 -----AFLQRRQRRRQDSRVVARSVRILVASFFLCWFPNHVVTLWGVLVKFDLVPWNSTF
:. :.::.. . ..: : ..:. : :::.: .:: : ...:
NP_001 KMRAVALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLLNLFVT----------
240 250 260 270 280
290 300 310 320 330 340
pF1KE2 YTIQTYVFPVTTCLAHSNSCLNPVLYCLLRREPRQALAGTFRDLRSRLWPQGGGWVQQVA
.... : :. :...::: ::.:: .: . :. . .. :: : .::
NP_001 -SLDATVNHVSLILSYANSCANPILYGFLSDNFRRFFQRVLC-LRCCLLEGAGGAEEEPL
290 300 310 320 330 340
350 360 370
pF1KE2 LKQVGRRWVASNPRESRPSTLLTNLDRGTPG
NP_001 DYYATALKSKGGAGCMCPPLPCQQEALQPEPGRKRIPLTRTTTF
350 360 370 380
>>NP_000902 (OMIM: 165195) delta-type opioid receptor [H (372 aa)
initn: 385 init1: 219 opt: 482 Z-score: 459.1 bits: 93.6 E(85289): 7.8e-19
Smith-Waterman score: 483; 31.7% identity (57.7% similar) in 331 aa overlap (2-312:5-321)
10 20 30 40
pF1KE2 MPTLNTSASPPTFFWANAS---------GGSVLSADDAPMPVKFLALRLMVALAYGL
:. .. .:: : :::: .:. :. . .. ::: . .. :.
NP_000 MEPAPSAGAELQPPLF--ANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSA
10 20 30 40 50
50 60 70 80 90 100
pF1KE2 VGAIGLLGNLAVLWVLSNCARRAPGPPSDTFVFNLALADLGLALTLPFWAAESALDFHWP
: :.:::::. :.. . .. . .. ..::::::: . :::: .:. .. ::
NP_000 VCAVGLLGNVLVMFGIVRYTKMKTA--TNIYIFNLALADALATSTLPFQSAKYLMET-WP
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE2 FGGALCKMVLTATVLNVYASIFLITALSVARYWVVAMAAGPGTHLSLFWARIATLAVWAA
:: ::: ::. :...::: .: .:: :: .: . . :.. .. .:.
NP_000 FGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVL
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE2 AALVTVPTAVFGVEGEVCGVRLCLLRFPSR--YWLGAYQLQRVVLAFMVPLGVITTSYLL
:. : :: :..: :. .:.:.::: :: . .. ..::.::. .::. : :
NP_000 ASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGL
180 190 200 210 220 230
230 240 250 260 270
pF1KE2 LLA------FLQRRQRRRQDSRVVARSVRILVASFFLCWFPNHV-VTLWGVLVKFDLVPW
.: .:. ... .. : ..: : ..:..: .:: : :. : .: .:: .:
NP_000 MLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVW-TLVDID----
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE2 NSTFYTIQTYVFPVTTCLA--HSNSCLNPVLYCLLRREPRQALAGTFRDLRSRLWPQGGG
: . :.: ..:: :::::: .:
NP_000 ----RRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFS
300 310 320 330 340
340 350 360 370
pF1KE2 WVQQVALKQVGRRWVASNPRESRPSTLLTNLDRGTPG
NP_000 RAREATARERVTACTPSDGPGGGAAA
350 360 370
374 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 07:56:27 2016 done: Sun Nov 6 07:56:28 2016
Total Scan time: 7.430 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]