Result of FASTA (omim) for
pFN21AE2201
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2201, 711 aa
1>>>pF1KE2201 711 - 711 aa - 711 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.6498+/-0.00048; mu= -10.1514+/- 0.030
mean_var=643.3793+/-132.915, 0's: 0 Z-trim(125.0): 110 B-trim: 868 in 1/56
Lambda= 0.050564
statistics sampled from 47769 (47913) to 47769 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.799), E-opt: 0.2 (0.562), width: 16
Scan time: 9.340
The best scores are: opt bits E(85289)
NP_003676 (OMIM: 603445) far upstream element-bind ( 711) 5155 391.3 6.7e-108
XP_005259725 (OMIM: 603445) PREDICTED: far upstrea ( 747) 5148 390.9 9.9e-108
XP_011526697 (OMIM: 603445) PREDICTED: far upstrea ( 703) 4743 361.3 7.5e-99
XP_016882897 (OMIM: 603445) PREDICTED: far upstrea ( 678) 4204 321.9 5e-87
XP_016882898 (OMIM: 603445) PREDICTED: far upstrea ( 642) 4182 320.3 1.5e-86
XP_016882899 (OMIM: 603445) PREDICTED: far upstrea ( 603) 4097 314.1 1e-84
XP_011540695 (OMIM: 603444) PREDICTED: far upstrea ( 667) 2333 185.4 6e-46
NP_003893 (OMIM: 603444) far upstream element-bind ( 644) 2330 185.2 6.9e-46
XP_016858230 (OMIM: 603444) PREDICTED: far upstrea ( 666) 2326 184.9 8.6e-46
XP_016858233 (OMIM: 603444) PREDICTED: far upstrea ( 643) 2323 184.7 9.8e-46
XP_016858232 (OMIM: 603444) PREDICTED: far upstrea ( 653) 2317 184.3 1.3e-45
XP_011540694 (OMIM: 603444) PREDICTED: far upstrea ( 687) 2126 170.4 2.2e-41
XP_016858231 (OMIM: 603444) PREDICTED: far upstrea ( 664) 2123 170.1 2.5e-41
XP_016858228 (OMIM: 603444) PREDICTED: far upstrea ( 688) 2114 169.5 4e-41
XP_011540693 (OMIM: 603444) PREDICTED: far upstrea ( 688) 2114 169.5 4e-41
NP_001290362 (OMIM: 603444) far upstream element-b ( 665) 2111 169.3 4.5e-41
XP_016858229 (OMIM: 603444) PREDICTED: far upstrea ( 675) 2105 168.8 6.2e-41
NP_003925 (OMIM: 603536) far upstream element-bind ( 572) 1591 131.2 1.1e-29
XP_011517475 (OMIM: 603536) PREDICTED: far upstrea ( 499) 1565 129.3 3.7e-29
XP_011517474 (OMIM: 603536) PREDICTED: far upstrea ( 514) 1547 128.0 9.3e-29
XP_005272289 (OMIM: 603536) PREDICTED: far upstrea ( 548) 1547 128.0 9.7e-29
XP_006717376 (OMIM: 603536) PREDICTED: far upstrea ( 485) 1515 125.6 4.5e-28
XP_011517476 (OMIM: 603536) PREDICTED: far upstrea ( 485) 1515 125.6 4.5e-28
XP_016870758 (OMIM: 603536) PREDICTED: far upstrea ( 461) 1471 122.4 4.1e-27
XP_016870760 (OMIM: 603536) PREDICTED: far upstrea ( 377) 1053 91.8 5.4e-18
XP_016870761 (OMIM: 603536) PREDICTED: far upstrea ( 377) 1053 91.8 5.4e-18
XP_016870759 (OMIM: 603536) PREDICTED: far upstrea ( 377) 1053 91.8 5.4e-18
XP_016870762 (OMIM: 603536) PREDICTED: far upstrea ( 353) 1010 88.6 4.5e-17
XP_016855821 (OMIM: 120260,600204,603932,614284) P ( 693) 385 43.4 0.0037
NP_000079 (OMIM: 114000,120150,130000,130060,16620 (1464) 391 44.2 0.0044
XP_005257115 (OMIM: 114000,120150,130000,130060,16 (1374) 388 43.9 0.0049
NP_001844 (OMIM: 120270,600969,603932) collagen al ( 684) 371 42.3 0.0075
>>NP_003676 (OMIM: 603445) far upstream element-binding (711 aa)
initn: 5155 init1: 5155 opt: 5155 Z-score: 2058.1 bits: 391.3 E(85289): 6.7e-108
Smith-Waterman score: 5155; 100.0% identity (100.0% similar) in 711 aa overlap (1-711:1-711)
10 20 30 40 50 60
pF1KE2 MSDYSTGGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MSDYSTGGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PPGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PPGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPES
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 KKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 SPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 PAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 DILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 DDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNW
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 GPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 PQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPH
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 QYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 PPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVAT
610 620 630 640 650 660
670 680 690 700 710
pF1KE2 GGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQQQAQ
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQQQAQ
670 680 690 700 710
>>XP_005259725 (OMIM: 603445) PREDICTED: far upstream el (747 aa)
initn: 5148 init1: 5148 opt: 5148 Z-score: 2055.1 bits: 390.9 E(85289): 9.9e-108
Smith-Waterman score: 5148; 100.0% identity (100.0% similar) in 710 aa overlap (1-710:1-710)
10 20 30 40 50 60
pF1KE2 MSDYSTGGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSDYSTGGPPPGPPPPAGGGGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PPGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPGGGGPGIRKDAFADAVQRARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPES
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 KKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 SPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 PAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 DILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 DDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNW
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 GPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 PQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPH
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 QYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 PPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVAT
610 620 630 640 650 660
670 680 690 700 710
pF1KE2 GGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQQQAQ
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQQQASGNCHPPPPP
670 680 690 700 710 720
XP_005 FSFQPPATVHPALVGSAGNPFPCGVCP
730 740
>>XP_011526697 (OMIM: 603445) PREDICTED: far upstream el (703 aa)
initn: 4743 init1: 4743 opt: 4743 Z-score: 1895.7 bits: 361.3 E(85289): 7.5e-99
Smith-Waterman score: 4743; 100.0% identity (100.0% similar) in 660 aa overlap (51-710:7-666)
30 40 50 60 70 80
pF1KE2 GGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPGGGGPGIRKDAFADAVQR
::::::::::::::::::::::::::::::
XP_011 MSDYSTGGGSAGGPSQPPGGGGPGIRKDAFADAVQR
10 20 30
90 100 110 120 130 140
pF1KE2 ARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQGDSISSQLGPIHPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQGDSISSQLGPIHPP
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE2 PRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPES
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE2 VQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQ
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE2 ERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSR
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE2 IGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCE
280 290 300 310 320 330
390 400 410 420 430 440
pF1KE2 HAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVI
340 350 360 370 380 390
450 460 470 480 490 500
pF1KE2 GRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLC
400 410 420 430 440 450
510 520 530 540 550 560
pF1KE2 PVGPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVGPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPH
460 470 480 490 500 510
570 580 590 600 610 620
pF1KE2 DPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQPPPTGQSDYTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQPPPTGQSDYTK
520 530 540 550 560 570
630 640 650 660 670 680
pF1KE2 AWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWAE
580 590 600 610 620 630
690 700 710
pF1KE2 YYRQQAAYYGQTPGPGGPQPPPTQQGQQQAQ
::::::::::::::::::::::::::::::
XP_011 YYRQQAAYYGQTPGPGGPQPPPTQQGQQQASGNCHPPPPPFSFQPPATVHPALVGSAGNP
640 650 660 670 680 690
>>XP_016882897 (OMIM: 603445) PREDICTED: far upstream el (678 aa)
initn: 4467 init1: 4010 opt: 4204 Z-score: 1683.4 bits: 321.9 E(85289): 5e-87
Smith-Waterman score: 4495; 96.2% identity (96.2% similar) in 660 aa overlap (51-710:7-641)
30 40 50 60 70 80
pF1KE2 GGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPGGGGPGIRKDAFADAVQR
::::::::::::::::::::::::::::::
XP_016 MSDYSTGGGSAGGPSQPPGGGGPGIRKDAFADAVQR
10 20 30
90 100 110 120 130 140
pF1KE2 ARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQGDSISSQLGPIHPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQGDSISSQLGPIHPP
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE2 PRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPES
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE2 VQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQ
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE2 ERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSR
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE2 IGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCE
280 290 300 310 320 330
390 400 410 420 430 440
pF1KE2 HAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVI
340 350 360 370 380 390
450 460 470 480 490 500
pF1KE2 GRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLC
400 410 420 430 440 450
510 520 530 540 550 560
pF1KE2 PVGPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVGPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPH
460 470 480 490 500 510
570 580 590 600 610 620
pF1KE2 DPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQPPPTGQSDYTK
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQG---------------
520 530 540 550 560
630 640 650 660 670 680
pF1KE2 AWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWAE
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ----------QQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWAE
570 580 590 600 610
690 700 710
pF1KE2 YYRQQAAYYGQTPGPGGPQPPPTQQGQQQAQ
::::::::::::::::::::::::::::::
XP_016 YYRQQAAYYGQTPGPGGPQPPPTQQGQQQASGNCHPPPPPFSFQPPATVHPALVGSAGNP
620 630 640 650 660 670
>>XP_016882898 (OMIM: 603445) PREDICTED: far upstream el (642 aa)
initn: 3995 init1: 3995 opt: 4182 Z-score: 1675.0 bits: 320.3 E(85289): 1.5e-86
Smith-Waterman score: 4502; 96.2% identity (96.2% similar) in 661 aa overlap (51-711:7-642)
30 40 50 60 70 80
pF1KE2 GGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPGGGGPGIRKDAFADAVQR
::::::::::::::::::::::::::::::
XP_016 MSDYSTGGGSAGGPSQPPGGGGPGIRKDAFADAVQR
10 20 30
90 100 110 120 130 140
pF1KE2 ARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQGDSISSQLGPIHPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQGDSISSQLGPIHPP
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE2 PRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPES
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE2 VQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQ
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE2 ERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGDRNEYGSR
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE2 IGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPPDRCE
280 290 300 310 320 330
390 400 410 420 430 440
pF1KE2 HAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFSIPTHKCGLVI
340 350 360 370 380 390
450 460 470 480 490 500
pF1KE2 GRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIEGPLC
400 410 420 430 440 450
510 520 530 540 550 560
pF1KE2 PVGPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVGPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPPPHQYPPQGWGNTYPQWQPPAPH
460 470 480 490 500 510
570 580 590 600 610 620
pF1KE2 DPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQGEPPQPPPTGQSDYTK
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGPAPAPAAPPAQG---------------
520 530 540 550 560
630 640 650 660 670 680
pF1KE2 AWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWAE
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ----------QQPQQPGAPPQQDYTKAWEEYYKKQAQVATGGGPGAPPGSQPDYSAAWAE
570 580 590 600 610
690 700 710
pF1KE2 YYRQQAAYYGQTPGPGGPQPPPTQQGQQQAQ
:::::::::::::::::::::::::::::::
XP_016 YYRQQAAYYGQTPGPGGPQPPPTQQGQQQAQ
620 630 640
>>XP_016882899 (OMIM: 603445) PREDICTED: far upstream el (603 aa)
initn: 4097 init1: 4097 opt: 4097 Z-score: 1641.8 bits: 314.1 E(85289): 1e-84
Smith-Waterman score: 4097; 100.0% identity (100.0% similar) in 566 aa overlap (145-710:1-566)
120 130 140 150 160 170
pF1KE2 GDQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDS
::::::::::::::::::::::::::::::
XP_016 MTEEYRVPDGMVGLIIGRGGEQINKIQQDS
10 20 30
180 190 200 210 220 230
pF1KE2 GCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GCKVQISPDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGT
40 50 60 70 80 90
240 250 260 270 280 290
pF1KE2 VQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQ
100 110 120 130 140 150
300 310 320 330 340 350
pF1KE2 ACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACEMVMDILRERDQGGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQNDAGV
160 170 180 190 200 210
360 370 380 390 400 410
pF1KE2 RIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIQFKQDDGTGPEKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRG
220 230 240 250 260 270
420 430 440 450 460 470
pF1KE2 RGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGQGNWGPPGGEMTFSIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKL
280 290 300 310 320 330
480 490 500 510 520 530
pF1KE2 FIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FIIRGSPQQIDHAKQLIEEKIEGPLCPVGPGPGGPGPAGPMGPFNPGPFNQGPPGAPPHA
340 350 360 370 380 390
540 550 560 570 580 590
pF1KE2 GGPPPHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGPPPHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPNAAWAAYYSHYYQQPPGPVPGP
400 410 420 430 440 450
600 610 620 630 640 650
pF1KE2 APAPAAPPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APAPAAPPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKK
460 470 480 490 500 510
660 670 680 690 700 710
pF1KE2 QAQVATGGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQQQAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAQVATGGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQQQASGNC
520 530 540 550 560 570
XP_016 HPPPPPFSFQPPATVHPALVGSAGNPFPCGVCP
580 590 600
>>XP_011540695 (OMIM: 603444) PREDICTED: far upstream el (667 aa)
initn: 1320 init1: 673 opt: 2333 Z-score: 945.8 bits: 185.4 E(85289): 6e-46
Smith-Waterman score: 2816; 62.9% identity (78.3% similar) in 682 aa overlap (50-705:10-642)
20 30 40 50 60 70
pF1KE2 GGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPGGGGPGIRKDAFADAVQ
:..::::: . :::: : .::: ::.:
XP_011 MADYSTVPPPSSGSAGGGG---GGGGGGGVNDAFKDALQ
10 20 30
80 90 100 110 120 130
pF1KE2 RARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQGDSISSQLGPIHP
:::::::::::::.:..:.. :.:.::::: :::::::..::.: :.::...:: :.:
XP_011 RARQIAAKIGGDAGTSLNSN--DYGYGGQKRPLEDGDQPDAKKVAPQNDSFGTQLPPMHQ
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE2 PP-RTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAP
:. :::::.:::::::.:::::::::..:::.::::.::.:::::::::: :::.:
XP_011 QQSRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTP
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE2 ESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQ
::::.:: .::.:: .:: .: :: . : ...::::::::.:::::::::::::::
XP_011 ESVQSAKRLLDQIVEKGRPAPG--FHHG--DGPGNAVQEIMIPASKAGLVIGKGGETIKQ
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE2 LQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGD-RNEY
:::::::::..:::: :::..:::::: ::::::::: :::.... :::::: . ::::
XP_011 LQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELI--RDQGGFREVRNEY
220 230 240 250 260
320 330 340 350 360 370
pF1KE2 GSRIGG--GIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGP
:::::: :::::.:: .::.::::.:::::::::::::::::: :::: ::.::.: ::
XP_011 GSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGP
270 280 290 300 310 320
380 390 400 410 420 430
pF1KE2 PDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNW--GPPGG--EMTFSI
::::.:::.::.:::.:...: :: :: ::::::::::::: ::::: :..: .
XP_011 PDRCQHAAEIITDLLRSVQAGNPGGPG-----PGGRGRGRGQGNWNMGPPGGLQEFNFIV
330 340 350 360 370 380
440 450 460 470 480 490
pF1KE2 PTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLI
:: : ::.::.:::..:.:.::.:: .:..:. :::.:::.::: :::.:::::.:.:::
XP_011 PTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLI
390 400 410 420 430 440
500 510 520 530
pF1KE2 EEKIEGPLCPVGPG--------------PGGPGPAGPMGPFNPGPFNQGPPGAPPHAGGP
:::: ::. :.:: :: :::. ::::.::.:.: :::: ::.
XP_011 EEKIGGPVNPLGPPVPHGPHGVPGPHGPPGPPGPGTPMGPYNPAPYNPGPPGPAPHG---
450 460 470 480 490 500
540 550 560 570 580 590
pF1KE2 PPHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPN-AAWAAYYSHYYQQ---PPGPVPG
:: : ::::::.::.:: :: ::.::.. ::: :::::::.::::: :: .:.
XP_011 PPAPYAPQGWGNAYPHWQQQAPPDPAKAGT---DPNSAAWAAYYAHYYQQQAQPPPAAPA
510 520 530 540 550
600 610 620 630 640 650
pF1KE2 PAPAPAAPPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYK
::. . .::. .: :.:: ::::::::::::.:: :
XP_011 GAPTTTQTNGQGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAP-----------------
560 570 580 590 600
660 670 680 690 700 710
pF1KE2 KQAQVATGGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQQQAQ
:::::.:::::::::::::::::::.:: : :: ::. :
XP_011 ----------TGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQCLPRPSTL
610 620 630 640 650
XP_011 GSAAKSTSAEDAASTKS
660
>>NP_003893 (OMIM: 603444) far upstream element-binding (644 aa)
initn: 1098 init1: 673 opt: 2330 Z-score: 944.8 bits: 185.2 E(85289): 6.9e-46
Smith-Waterman score: 2831; 63.3% identity (78.7% similar) in 684 aa overlap (50-707:10-644)
20 30 40 50 60 70
pF1KE2 GGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPGGGGPGIRKDAFADAVQ
:..::::: . :::: : .::: ::.:
NP_003 MADYSTVPPPSSGSAGGGG---GGGGGGGVNDAFKDALQ
10 20 30
80 90 100 110 120 130
pF1KE2 RARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQGDSISSQLGPIHP
:::::::::::::.:..:.. :.:.::::: :::::::..::.: :.::...:: :.:
NP_003 RARQIAAKIGGDAGTSLNSN--DYGYGGQKRPLEDGDQPDAKKVAPQNDSFGTQLPPMHQ
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE2 PP-RTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAP
:. :::::.:::::::.:::::::::..:::.::::.::.:::::::::: :::.:
NP_003 QQSRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTP
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE2 ESVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQ
::::.:: .::.:: .:: .: :: . : ...::::::::.:::::::::::::::
NP_003 ESVQSAKRLLDQIVEKGRPAPG--FHHG--DGPGNAVQEIMIPASKAGLVIGKGGETIKQ
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE2 LQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGD-RNEY
:::::::::..:::: :::..:::::: ::::::::: :::.... :::::: . ::::
NP_003 LQERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELI--RDQGGFREVRNEY
220 230 240 250 260
320 330 340 350 360 370
pF1KE2 GSRIGG--GIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGP
:::::: :::::.:: .::.::::.:::::::::::::::::: :::: ::.::.: ::
NP_003 GSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGP
270 280 290 300 310 320
380 390 400 410 420 430
pF1KE2 PDRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNW--GPPGG--EMTFSI
::::.:::.::.:::.:...: :: ::: ::::::::::::: ::::: :..: .
NP_003 PDRCQHAAEIITDLLRSVQAGNPG---GPG--PGGRGRGRGQGNWNMGPPGGLQEFNFIV
330 340 350 360 370 380
440 450 460 470 480 490
pF1KE2 PTHKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLI
:: : ::.::.:::..:.:.::.:: .:..:. :::.:::.::: :::.:::::.:.:::
NP_003 PTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLI
390 400 410 420 430 440
500 510 520 530
pF1KE2 EEKIEGPLCPVGP----GPGG----------PGPAGPMGPFNPGPFNQGPPGAPPHAGGP
:::: ::. :.:: :: : :::. ::::.::.:.: :::: ::.
NP_003 EEKIGGPVNPLGPPVPHGPHGVPGPHGPPGPPGPGTPMGPYNPAPYNPGPPGPAPHG---
450 460 470 480 490 500
540 550 560 570 580 590
pF1KE2 PPHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPN-AAWAAYYSHYYQQ---PPGPVPG
:: : ::::::.::.:: :: ::.::.. ::: :::::::.::::: :: .:.
NP_003 PPAPYAPQGWGNAYPHWQQQAPPDPAKAGT---DPNSAAWAAYYAHYYQQQAQPPPAAPA
510 520 530 540 550
600 610 620 630 640 650
pF1KE2 PAPAPAAPPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYK
::. . .::. .: :.:: ::::::::::::.:: :
NP_003 GAPTTTQTNGQGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAP-----------------
560 570 580 590 600
660 670 680 690 700 710
pF1KE2 KQAQVATGGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQQQAQ
:::::.:::::::::::::::::::.:: : :: ::. :::
NP_003 ----------TGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQGQ
610 620 630 640
>>XP_016858230 (OMIM: 603444) PREDICTED: far upstream el (666 aa)
initn: 1579 init1: 673 opt: 2326 Z-score: 943.1 bits: 184.9 E(85289): 8.6e-46
Smith-Waterman score: 2828; 63.0% identity (78.4% similar) in 681 aa overlap (50-705:10-641)
20 30 40 50 60 70
pF1KE2 GGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPGGGGPGIRKDAFADAVQ
:..::::: . :::: : .::: ::.:
XP_016 MADYSTVPPPSSGSAGGGG---GGGGGGGVNDAFKDALQ
10 20 30
80 90 100 110 120 130
pF1KE2 RARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQGDSISSQLGPIHP
:::::::::::::.:..:.. :.:.::::: :::::::..::.: :.::...:: :.:
XP_016 RARQIAAKIGGDAGTSLNSN--DYGYGGQKRPLEDGDQPDAKKVAPQNDSFGTQLPPMHQ
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE2 PPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPE
:. :::::.:::::::.:::::::::..:::.::::.::.:::::::::: :::.::
XP_016 QQRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPE
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE2 SVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQL
:::.:: .::.:: .:: .: :: . : ...::::::::.::::::::::::::::
XP_016 SVQSAKRLLDQIVEKGRPAPG--FHHG--DGPGNAVQEIMIPASKAGLVIGKGGETIKQL
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE2 QERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGD-RNEYG
::::::::..:::: :::..:::::: ::::::::: :::.... :::::: . :::::
XP_016 QERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELI--RDQGGFREVRNEYG
220 230 240 250 260
320 330 340 350 360 370
pF1KE2 SRIGG--GIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPP
::::: :::::.:: .::.::::.:::::::::::::::::: :::: ::.::.: :::
XP_016 SRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPP
270 280 290 300 310 320
380 390 400 410 420 430
pF1KE2 DRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNW--GPPGG--EMTFSIP
:::.:::.::.:::.:...: :: :: ::::::::::::: ::::: :..: .:
XP_016 DRCQHAAEIITDLLRSVQAGNPGGPG-----PGGRGRGRGQGNWNMGPPGGLQEFNFIVP
330 340 350 360 370 380
440 450 460 470 480 490
pF1KE2 THKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIE
: : ::.::.:::..:.:.::.:: .:..:. :::.:::.::: :::.:::::.:.::::
XP_016 TGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIE
390 400 410 420 430 440
500 510 520 530
pF1KE2 EKIEGPLCPVGPG--------------PGGPGPAGPMGPFNPGPFNQGPPGAPPHAGGPP
::: ::. :.:: :: :::. ::::.::.:.: :::: ::. :
XP_016 EKIGGPVNPLGPPVPHGPHGVPGPHGPPGPPGPGTPMGPYNPAPYNPGPPGPAPHG---P
450 460 470 480 490 500
540 550 560 570 580 590
pF1KE2 PHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPN-AAWAAYYSHYYQQ---PPGPVPGP
: : ::::::.::.:: :: ::.::.. ::: :::::::.::::: :: .:.
XP_016 PAPYAPQGWGNAYPHWQQQAPPDPAKAGT---DPNSAAWAAYYAHYYQQQAQPPPAAPAG
510 520 530 540 550
600 610 620 630 640 650
pF1KE2 APAPAAPPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKK
::. . .::. .: :.:: ::::::::::::.:: :
XP_016 APTTTQTNGQGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAP------------------
560 570 580 590
660 670 680 690 700 710
pF1KE2 QAQVATGGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQQQAQ
:::::.:::::::::::::::::::.:: : :: ::. :
XP_016 ---------TGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQCLPRPSTLG
600 610 620 630 640 650
XP_016 SAAKSTSAEDAASTKS
660
>>XP_016858233 (OMIM: 603444) PREDICTED: far upstream el (643 aa)
initn: 1357 init1: 673 opt: 2323 Z-score: 942.1 bits: 184.7 E(85289): 9.8e-46
Smith-Waterman score: 2843; 63.4% identity (78.8% similar) in 683 aa overlap (50-707:10-643)
20 30 40 50 60 70
pF1KE2 GGGAGGAGGGPPPGPPGAGDRGGGGPGGGGPGGGSAGGPSQPPGGGGPGIRKDAFADAVQ
:..::::: . :::: : .::: ::.:
XP_016 MADYSTVPPPSSGSAGGGG---GGGGGGGVNDAFKDALQ
10 20 30
80 90 100 110 120 130
pF1KE2 RARQIAAKIGGDAATTVNNSTPDFGFGGQKRQLEDGDQPESKKLASQGDSISSQLGPIHP
:::::::::::::.:..:.. :.:.::::: :::::::..::.: :.::...:: :.:
XP_016 RARQIAAKIGGDAGTSLNSN--DYGYGGQKRPLEDGDQPDAKKVAPQNDSFGTQLPPMHQ
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE2 PPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLPERSVSLTGAPE
:. :::::.:::::::.:::::::::..:::.::::.::.:::::::::: :::.::
XP_016 QQRSVMTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPE
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE2 SVQKAKMMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQL
:::.:: .::.:: .:: .: :: . : ...::::::::.::::::::::::::::
XP_016 SVQSAKRLLDQIVEKGRPAPG--FHHG--DGPGNAVQEIMIPASKAGLVIGKGGETIKQL
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE2 QERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRERDQGGFGD-RNEYG
::::::::..:::: :::..:::::: ::::::::: :::.... :::::: . :::::
XP_016 QERAGVKMVMIQDGPQNTGADKPLRITGDPYKVQQAKEMVLELI--RDQGGFREVRNEYG
220 230 240 250 260
320 330 340 350 360 370
pF1KE2 SRIGG--GIDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGPEKIAHIMGPP
::::: :::::.:: .::.::::.:::::::::::::::::: :::: ::.::.: :::
XP_016 SRIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPP
270 280 290 300 310 320
380 390 400 410 420 430
pF1KE2 DRCEHAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNW--GPPGG--EMTFSIP
:::.:::.::.:::.:...: :: ::: ::::::::::::: ::::: :..: .:
XP_016 DRCQHAAEIITDLLRSVQAGNPG---GPG--PGGRGRGRGQGNWNMGPPGGLQEFNFIVP
330 340 350 360 370 380
440 450 460 470 480 490
pF1KE2 THKCGLVIGRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIE
: : ::.::.:::..:.:.::.:: .:..:. :::.:::.::: :::.:::::.:.::::
XP_016 TGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIE
390 400 410 420 430 440
500 510 520 530
pF1KE2 EKIEGPLCPVGP----GPGG----------PGPAGPMGPFNPGPFNQGPPGAPPHAGGPP
::: ::. :.:: :: : :::. ::::.::.:.: :::: ::. :
XP_016 EKIGGPVNPLGPPVPHGPHGVPGPHGPPGPPGPGTPMGPYNPAPYNPGPPGPAPHG---P
450 460 470 480 490 500
540 550 560 570 580 590
pF1KE2 PHQYPPQGWGNTYPQWQPPAPHDPSKAAAAAADPN-AAWAAYYSHYYQQ---PPGPVPGP
: : ::::::.::.:: :: ::.::.. ::: :::::::.::::: :: .:.
XP_016 PAPYAPQGWGNAYPHWQQQAPPDPAKAGT---DPNSAAWAAYYAHYYQQQAQPPPAAPAG
510 520 530 540 550
600 610 620 630 640 650
pF1KE2 APAPAAPPAQGEPPQPPPTGQSDYTKAWEEYYKKIGQQPQQPGAPPQQDYTKAWEEYYKK
::. . .::. .: :.:: ::::::::::::.:: :
XP_016 APTTTQTNGQGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAP------------------
560 570 580 590
660 670 680 690 700 710
pF1KE2 QAQVATGGGPGAPPGSQPDYSAAWAEYYRQQAAYYGQTPGPGGPQPPPTQQGQQQAQ
:::::.:::::::::::::::::::.:: : :: ::. :::
XP_016 ---------TGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQGQ
600 610 620 630 640
711 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 19:46:15 2016 done: Mon Nov 7 19:46:16 2016
Total Scan time: 9.340 Total Display time: 0.110
Function used was FASTA [36.3.4 Apr, 2011]