Result of FASTA (omim) for
pFN21AE2195
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2195, 418 aa
1>>>pF1KE2195 418 - 418 aa - 418 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.3432+/-0.000382; mu= 23.0347+/- 0.024
mean_var=84.2796+/-20.841, 0's: 0 Z-trim(112.2): 182 B-trim: 2460 in 2/55
Lambda= 0.139705
statistics sampled from 20763 (21060) to 20763 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.604), E-opt: 0.2 (0.247), width: 16
Scan time: 7.750
The best scores are: opt bits E(85289)
NP_942011 (OMIM: 176806) prostaglandin E2 receptor ( 418) 2777 570.0 3.7e-162
NP_942009 (OMIM: 176806) prostaglandin E2 receptor ( 374) 2466 507.3 2.6e-143
NP_001119516 (OMIM: 176806) prostaglandin E2 recep ( 390) 2416 497.3 2.9e-140
NP_942007 (OMIM: 176806) prostaglandin E2 receptor ( 390) 2416 497.3 2.9e-140
NP_942012 (OMIM: 176806) prostaglandin E2 receptor ( 390) 2416 497.3 2.9e-140
XP_011540112 (OMIM: 176806) PREDICTED: prostagland ( 410) 2416 497.3 2.9e-140
NP_942008 (OMIM: 176806) prostaglandin E2 receptor ( 388) 2408 495.6 8.7e-140
NP_942010 (OMIM: 176806) prostaglandin E2 receptor ( 365) 2407 495.4 9.7e-140
XP_016857362 (OMIM: 600563) PREDICTED: prostagland ( 291) 457 102.2 1.7e-21
NP_001034674 (OMIM: 600563) prostaglandin F2-alpha ( 297) 457 102.3 1.8e-21
NP_000950 (OMIM: 600563) prostaglandin F2-alpha re ( 359) 457 102.4 2e-21
NP_000946 (OMIM: 176802) prostaglandin E2 receptor ( 402) 406 92.1 2.6e-18
XP_011526516 (OMIM: 188070,614009) PREDICTED: thro ( 343) 401 91.0 4.8e-18
NP_001051 (OMIM: 188070,614009) thromboxane A2 rec ( 343) 401 91.0 4.8e-18
NP_963998 (OMIM: 188070,614009) thromboxane A2 rec ( 407) 401 91.1 5.3e-18
NP_000944 (OMIM: 604687,607277) prostaglandin D2 r ( 359) 382 87.2 7e-17
XP_005267948 (OMIM: 604687,607277) PREDICTED: pros ( 359) 382 87.2 7e-17
NP_000947 (OMIM: 176804,208550) prostaglandin E2 r ( 358) 379 86.6 1.1e-16
NP_000951 (OMIM: 600022) prostacyclin receptor [Ho ( 386) 372 85.3 2.9e-16
XP_005259152 (OMIM: 600022) PREDICTED: prostacycli ( 257) 368 84.2 4e-16
XP_005259150 (OMIM: 600022) PREDICTED: prostacycli ( 342) 369 84.6 4.2e-16
XP_016865148 (OMIM: 601586) PREDICTED: prostagland ( 313) 355 81.7 2.8e-15
XP_016865147 (OMIM: 601586) PREDICTED: prostagland ( 325) 355 81.7 2.9e-15
XP_016865146 (OMIM: 601586) PREDICTED: prostagland ( 326) 355 81.7 2.9e-15
XP_016865145 (OMIM: 601586) PREDICTED: prostagland ( 350) 355 81.8 3e-15
NP_000949 (OMIM: 601586) prostaglandin E2 receptor ( 488) 355 82.0 3.7e-15
NP_001268398 (OMIM: 604687,607277) prostaglandin D ( 296) 310 72.6 1.4e-12
NP_150598 (OMIM: 606665) melanopsin isoform 1 [Hom ( 478) 230 56.8 1.4e-07
XP_016872445 (OMIM: 606665) PREDICTED: melanopsin ( 528) 230 56.8 1.5e-07
NP_001025186 (OMIM: 606665) melanopsin isoform 2 [ ( 489) 213 53.4 1.5e-06
XP_016872444 (OMIM: 606665) PREDICTED: melanopsin ( 539) 213 53.4 1.6e-06
NP_000907 (OMIM: 167055) oxytocin receptor [Homo s ( 389) 206 51.8 3.5e-06
XP_011532064 (OMIM: 167055) PREDICTED: oxytocin re ( 389) 206 51.8 3.5e-06
XP_016872446 (OMIM: 606665) PREDICTED: melanopsin ( 405) 199 50.4 9.5e-06
NP_001948 (OMIM: 131243,157300,616367) endothelin- ( 427) 180 46.6 0.00014
NP_000397 (OMIM: 138850,146110) gonadotropin-relea ( 328) 165 43.5 0.00097
XP_011535421 (OMIM: 275200,603372,603373,609152) P ( 671) 168 44.5 0.00098
NP_000360 (OMIM: 275200,603372,603373,609152) thyr ( 764) 168 44.5 0.0011
XP_005268094 (OMIM: 275200,603372,603373,609152) P ( 764) 168 44.5 0.0011
NP_937822 (OMIM: 606925) pyroglutamylated RFamide ( 431) 164 43.4 0.0013
NP_001184113 (OMIM: 610118) probable G-protein cou ( 333) 162 42.9 0.0015
NP_001041 (OMIM: 182452) somatostatin receptor typ ( 369) 160 42.5 0.0021
NP_114142 (OMIM: 606916) probable G-protein couple ( 451) 160 42.6 0.0024
XP_016857927 (OMIM: 606916) PREDICTED: probable G- ( 451) 160 42.6 0.0024
NP_055137 (OMIM: 606695) opsin-3 [Homo sapiens] ( 402) 159 42.4 0.0025
NP_000667 (OMIM: 600446) adenosine receptor A2b [H ( 332) 158 42.1 0.0026
NP_001269117 (OMIM: 300201) cysteinyl leukotriene ( 337) 157 41.9 0.003
NP_001269115 (OMIM: 300201) cysteinyl leukotriene ( 337) 157 41.9 0.003
NP_001269116 (OMIM: 300201) cysteinyl leukotriene ( 337) 157 41.9 0.003
NP_006630 (OMIM: 300201) cysteinyl leukotriene rec ( 337) 157 41.9 0.003
>>NP_942011 (OMIM: 176806) prostaglandin E2 receptor EP3 (418 aa)
initn: 2777 init1: 2777 opt: 2777 Z-score: 3032.2 bits: 570.0 E(85289): 3.7e-162
Smith-Waterman score: 2777; 100.0% identity (100.0% similar) in 418 aa overlap (1-418:1-418)
10 20 30 40 50 60
pF1KE2 MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQM
310 320 330 340 350 360
370 380 390 400 410
pF1KE2 RKRRLREQLICSLQNSQIQRATAHCGQVQTYRVLNREEMEVLVSSINVYTRISTVKTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 RKRRLREQLICSLQNSQIQRATAHCGQVQTYRVLNREEMEVLVSSINVYTRISTVKTE
370 380 390 400 410
>>NP_942009 (OMIM: 176806) prostaglandin E2 receptor EP3 (374 aa)
initn: 2466 init1: 2466 opt: 2466 Z-score: 2693.9 bits: 507.3 E(85289): 2.6e-143
Smith-Waterman score: 2466; 100.0% identity (100.0% similar) in 368 aa overlap (1-368:1-368)
10 20 30 40 50 60
pF1KE2 MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQM
310 320 330 340 350 360
370 380 390 400 410
pF1KE2 RKRRLREQLICSLQNSQIQRATAHCGQVQTYRVLNREEMEVLVSSINVYTRISTVKTE
::::::::
NP_942 RKRRLREQEEFWGN
370
>>NP_001119516 (OMIM: 176806) prostaglandin E2 receptor (390 aa)
initn: 2438 init1: 2416 opt: 2416 Z-score: 2639.3 bits: 497.3 E(85289): 2.9e-140
Smith-Waterman score: 2416; 99.7% identity (100.0% similar) in 361 aa overlap (1-361:1-361)
10 20 30 40 50 60
pF1KE2 MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQM
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
NP_001 MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQI
310 320 330 340 350 360
370 380 390 400 410
pF1KE2 RKRRLREQLICSLQNSQIQRATAHCGQVQTYRVLNREEMEVLVSSINVYTRISTVKTE
:
NP_001 RYHTNNYASSSTSLPCQCSSTLMWSDHLER
370 380 390
>>NP_942007 (OMIM: 176806) prostaglandin E2 receptor EP3 (390 aa)
initn: 2438 init1: 2416 opt: 2416 Z-score: 2639.3 bits: 497.3 E(85289): 2.9e-140
Smith-Waterman score: 2416; 99.7% identity (100.0% similar) in 361 aa overlap (1-361:1-361)
10 20 30 40 50 60
pF1KE2 MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQM
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
NP_942 MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQI
310 320 330 340 350 360
370 380 390 400 410
pF1KE2 RKRRLREQLICSLQNSQIQRATAHCGQVQTYRVLNREEMEVLVSSINVYTRISTVKTE
:
NP_942 RYHTNNYASSSTSLPCQCSSTLMWSDHLER
370 380 390
>>NP_942012 (OMIM: 176806) prostaglandin E2 receptor EP3 (390 aa)
initn: 2438 init1: 2416 opt: 2416 Z-score: 2639.3 bits: 497.3 E(85289): 2.9e-140
Smith-Waterman score: 2416; 99.7% identity (100.0% similar) in 361 aa overlap (1-361:1-361)
10 20 30 40 50 60
pF1KE2 MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQM
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
NP_942 MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQI
310 320 330 340 350 360
370 380 390 400 410
pF1KE2 RKRRLREQLICSLQNSQIQRATAHCGQVQTYRVLNREEMEVLVSSINVYTRISTVKTE
:
NP_942 RYHTNNYASSSTSLPCQCSSTLMWSDHLER
370 380 390
>>XP_011540112 (OMIM: 176806) PREDICTED: prostaglandin E (410 aa)
initn: 2438 init1: 2416 opt: 2416 Z-score: 2639.0 bits: 497.3 E(85289): 2.9e-140
Smith-Waterman score: 2416; 99.7% identity (100.0% similar) in 361 aa overlap (1-361:1-361)
10 20 30 40 50 60
pF1KE2 MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQM
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
XP_011 MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQI
310 320 330 340 350 360
370 380 390 400 410
pF1KE2 RKRRLREQLICSLQNSQIQRATAHCGQVQTYRVLNREEMEVLVSSINVYTRISTVKTE
:
XP_011 RYHTNNYASSSTSLPCQCSSTLMWSDHLERRNFGEIKTCLSARITSLEAP
370 380 390 400 410
>>NP_942008 (OMIM: 176806) prostaglandin E2 receptor EP3 (388 aa)
initn: 2430 init1: 2408 opt: 2408 Z-score: 2630.6 bits: 495.6 E(85289): 8.7e-140
Smith-Waterman score: 2408; 99.7% identity (100.0% similar) in 360 aa overlap (1-360:1-360)
10 20 30 40 50 60
pF1KE2 MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQM
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
NP_942 MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQV
310 320 330 340 350 360
370 380 390 400 410
pF1KE2 RKRRLREQLICSLQNSQIQRATAHCGQVQTYRVLNREEMEVLVSSINVYTRISTVKTE
NP_942 ANAVSSCSNDGQKGQPISLSNEIIQTEA
370 380
>>NP_942010 (OMIM: 176806) prostaglandin E2 receptor EP3 (365 aa)
initn: 2407 init1: 2407 opt: 2407 Z-score: 2629.8 bits: 495.4 E(85289): 9.7e-140
Smith-Waterman score: 2407; 100.0% identity (100.0% similar) in 359 aa overlap (1-359:1-359)
10 20 30 40 50 60
pF1KE2 MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQM
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQE
310 320 330 340 350 360
370 380 390 400 410
pF1KE2 RKRRLREQLICSLQNSQIQRATAHCGQVQTYRVLNREEMEVLVSSINVYTRISTVKTE
NP_942 EFWGN
>>XP_016857362 (OMIM: 600563) PREDICTED: prostaglandin F (291 aa)
initn: 530 init1: 386 opt: 457 Z-score: 506.8 bits: 102.2 E(85289): 1.7e-21
Smith-Waterman score: 541; 34.9% identity (66.9% similar) in 272 aa overlap (50-321:28-284)
20 30 40 50 60 70
pF1KE2 SYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLLTGFVGNALAMLLVSRSYRR
.:: : . .. .:...:.::. .. ..:.:
XP_016 MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQR
10 20 30 40 50
80 90 100 110 120 130
pF1KE2 RESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRWEHIDPSGRLCTFFGLTMTV
..: : :::: . :..::. :.:.. ... :: : ..: ..: :. ::..::. :.
XP_016 FRQKSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVF
60 70 80 90 100 110
140 150 160 170 180 190
pF1KE2 FGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLGVWLAVLAFALLPVLGVGQY
:: :...:.::.:: ... : ...... .. .. .: :: : .. .::::.:: .:
XP_016 SGLCPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDY
120 130 140 150 160 170
200 210 220 230 240 250
pF1KE2 TVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLLALTVTFSCNLATIKALVSR
.: :::: .: . ..: . :. :.::::::: :.. :: : .:. :
XP_016 KIQASRTWCFYNT-------EDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLL-R
180 190 200 210 220
260 270 280 290 300 310
pF1KE2 CRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEHCKTHT
. : ::. : : .:::..:::: .::::.: . ..:.: :. :..
XP_016 VKFK---SQQHRQGRSHHLEMVIQLLAIMCVSCICWSPFLGY--RIILNGK--EKYKVYE
230 240 250 260 270 280
320 330 340 350 360 370
pF1KE2 EKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQMRKRRLREQLICSLQNSQIQ
:.
XP_016 EQSDFLHRK
290
>>NP_001034674 (OMIM: 600563) prostaglandin F2-alpha rec (297 aa)
initn: 530 init1: 386 opt: 457 Z-score: 506.7 bits: 102.3 E(85289): 1.8e-21
Smith-Waterman score: 541; 34.9% identity (66.9% similar) in 272 aa overlap (50-321:28-284)
20 30 40 50 60 70
pF1KE2 SYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLLTGFVGNALAMLLVSRSYRR
.:: : . .. .:...:.::. .. ..:.:
NP_001 MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQR
10 20 30 40 50
80 90 100 110 120 130
pF1KE2 RESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRWEHIDPSGRLCTFFGLTMTV
..: : :::: . :..::. :.:.. ... :: : ..: ..: :. ::..::. :.
NP_001 FRQKSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVF
60 70 80 90 100 110
140 150 160 170 180 190
pF1KE2 FGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLGVWLAVLAFALLPVLGVGQY
:: :...:.::.:: ... : ...... .. .. .: :: : .. .::::.:: .:
NP_001 SGLCPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDY
120 130 140 150 160 170
200 210 220 230 240 250
pF1KE2 TVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLLALTVTFSCNLATIKALVSR
.: :::: .: . ..: . :. :.::::::: :.. :: : .:. :
NP_001 KIQASRTWCFYNT-------EDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLL-R
180 190 200 210 220
260 270 280 290 300 310
pF1KE2 CRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEHCKTHT
. : ::. : : .:::..:::: .::::.: . ..:.: :. :..
NP_001 VKFK---SQQHRQGRSHHLEMVIQLLAIMCVSCICWSPFLGY--RIILNGK--EKYKVYE
230 240 250 260 270 280
320 330 340 350 360 370
pF1KE2 EKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQMRKRRLREQLICSLQNSQIQ
:.
NP_001 EQSDFLHRLQWPTLE
290
418 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 02:41:33 2016 done: Tue Nov 8 02:41:34 2016
Total Scan time: 7.750 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]