Result of FASTA (ccds) for
pFN21AE2111
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2111, 826 aa
1>>>pF1KE2111 826 - 826 aa - 826 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.1679+/-0.000809; mu= 14.7653+/- 0.049
mean_var=155.9614+/-31.059, 0's: 0 Z-trim(113.8): 48 B-trim: 105 in 1/50
Lambda= 0.102699
statistics sampled from 14390 (14437) to 14390 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.759), E-opt: 0.2 (0.443), width: 16
Scan time: 4.970
The best scores are: opt bits E(32554)
CCDS10406.1 AXIN1 gene_id:8312|Hs108|chr16 ( 826) 5656 850.1 0
CCDS10405.1 AXIN1 gene_id:8312|Hs108|chr16 ( 862) 5011 754.5 1.7e-217
CCDS11662.1 AXIN2 gene_id:8313|Hs108|chr17 ( 843) 417 73.9 1.3e-12
>>CCDS10406.1 AXIN1 gene_id:8312|Hs108|chr16 (826 aa)
initn: 5656 init1: 5656 opt: 5656 Z-score: 4534.9 bits: 850.1 E(32554): 0
Smith-Waterman score: 5656; 99.9% identity (100.0% similar) in 826 aa overlap (1-826:1-826)
10 20 30 40 50 60
pF1KE2 MNIQEQGFPLDLGASFTEDAPRPPVPGEEGELVSTDPRPASYSFCSGKGVGIKGETSTAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MNIQEQGFPLDLGASFTEDAPRPPVPGEEGELVSTDPRPASYSFCSGKGVGIKGETSTAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PRRSDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 PRRSDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 CTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 CTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 MFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGISGYLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGISGYLPT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 LNEDEEWKCDQDMDEDDGRDAAPPGRLPQKLLLETAAPRVSSSRRYSEGREFRYGSWREP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 LNEDEEWKCDQDMDEDDGRDAAPPGRLPQKLLLETAAPRVSSSRRYSEGREFRYGSWREP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 VNPYYVNAGYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRIRKQHRREMQESV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 VNPYYVNAGYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRIRKQHRREMQESV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 QVNGRVPLPHIPRTYRVPKEVRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 QVNGRVPLPHIPRTYRVPKEVRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 EGEDSDPSSGPPGPCHKLPPAPAWHHFPPRCVDMGCAGLRDAHEENPESILDEHVQRVLR
::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 EGEDGDPSSGPPGPCHKLPPAPAWHHFPPRCVDMGCAGLRDAHEENPESILDEHVQRVLR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 TPGRQSPGPGHRSPDSGHVAKMPVALGGAASGHGKHVPKSGAKLDAAGLHHHRHVHHHVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 TPGRQSPGPGHRSPDSGHVAKMPVALGGAASGHGKHVPKSGAKLDAAGLHHHRHVHHHVH
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 HSTARPKEQVEAEATRRAQSSFAWGLEPHSHGARSRGYSESVGAAPNASDGLAHSGKVGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 HSTARPKEQVEAEATRRAQSSFAWGLEPHSHGARSRGYSESVGAAPNASDGLAHSGKVGV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 ACKRNAKKAESGKSASTEVPGASEDAEKNQKIMQWIIEGEKEISRHRRTGHGSSGTRKPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 ACKRNAKKAESGKSASTEVPGASEDAEKNQKIMQWIIEGEKEISRHRRTGHGSSGTRKPQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 PHENSRPLSLEHPWAGPQLRTSVQPSHLFIQDPTMPPHPAPNPLTQLEEARRRLEEEEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 PHENSRPLSLEHPWAGPQLRTSVQPSHLFIQDPTMPPHPAPNPLTQLEEARRRLEEEEKR
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 ASRAPSKQRTRSQRKVGGGSAQPCDSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 ASRAPSKQRTRSQRKVGGGSAQPCDSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTK
730 740 750 760 770 780
790 800 810 820
pF1KE2 KGSYRYYFKKVSDEFDCGVVFEEVREDEAVLPVFEEKIIGKVEKVD
::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 KGSYRYYFKKVSDEFDCGVVFEEVREDEAVLPVFEEKIIGKVEKVD
790 800 810 820
>>CCDS10405.1 AXIN1 gene_id:8312|Hs108|chr16 (862 aa)
initn: 5010 init1: 5010 opt: 5011 Z-score: 4018.2 bits: 754.5 E(32554): 1.7e-217
Smith-Waterman score: 5549; 95.7% identity (95.8% similar) in 858 aa overlap (1-822:1-858)
10 20 30 40 50 60
pF1KE2 MNIQEQGFPLDLGASFTEDAPRPPVPGEEGELVSTDPRPASYSFCSGKGVGIKGETSTAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MNIQEQGFPLDLGASFTEDAPRPPVPGEEGELVSTDPRPASYSFCSGKGVGIKGETSTAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PRRSDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 PRRSDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 CTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 CTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 MFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGISGYLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGISGYLPT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 LNEDEEWKCDQDMDEDDGRDAAPPGRLPQKLLLETAAPRVSSSRRYSEGREFRYGSWREP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 LNEDEEWKCDQDMDEDDGRDAAPPGRLPQKLLLETAAPRVSSSRRYSEGREFRYGSWREP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 VNPYYVNAGYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRIRKQHRREMQESV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 VNPYYVNAGYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRIRKQHRREMQESV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 QVNGRVPLPHIPRTYRVPKEVRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 QVNGRVPLPHIPRTYRVPKEVRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 EGEDSDPSSGPPGPCHKLPPAPAWHHFPPRCVDMGCAGLRDAHEENPESILDEHVQRVLR
::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 EGEDGDPSSGPPGPCHKLPPAPAWHHFPPRCVDMGCAGLRDAHEENPESILDEHVQRVLR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 TPGRQSPGPGHRSPDSGHVAKMPVALGGAASGHGKHVPKSGAKLDAAGLHHHRHVHHHVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 TPGRQSPGPGHRSPDSGHVAKMPVALGGAASGHGKHVPKSGAKLDAAGLHHHRHVHHHVH
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 HSTARPKEQVEAEATRRAQSSFAWGLEPHSHGARSRGYSESVGAAPNASDGLAHSGKVGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 HSTARPKEQVEAEATRRAQSSFAWGLEPHSHGARSRGYSESVGAAPNASDGLAHSGKVGV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 ACKRNAKKAESGKSASTEVPGASEDAEKNQKIMQWIIEGEKEISRHRRTGHGSSGTRKPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 ACKRNAKKAESGKSASTEVPGASEDAEKNQKIMQWIIEGEKEISRHRRTGHGSSGTRKPQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 PHENSRPLSLEHPWAGPQLRTSVQPSHLFIQDPTMPPHPAPNPLTQLEEARRRLEEEEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 PHENSRPLSLEHPWAGPQLRTSVQPSHLFIQDPTMPPHPAPNPLTQLEEARRRLEEEEKR
670 680 690 700 710 720
730 740
pF1KE2 ASRAPSKQR------------------------------------TRSQRKVGGGSAQPC
::::::::: :::::::::::::::
CCDS10 ASRAPSKQRYVQEVMRRGRACVRPACAPVLHVVPAVSDMELSETETRSQRKVGGGSAQPC
730 740 750 760 770 780
750 760 770 780 790 800
pF1KE2 DSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDCGVVFEEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 DSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDCGVVFEEV
790 800 810 820 830 840
810 820
pF1KE2 REDEAVLPVFEEKIIGKVEKVD
::::::::::::::::::
CCDS10 REDEAVLPVFEEKIIGKVEKVD
850 860
>>CCDS11662.1 AXIN2 gene_id:8313|Hs108|chr17 (843 aa)
initn: 1655 init1: 381 opt: 417 Z-score: 339.8 bits: 73.9 E(32554): 1.3e-12
Smith-Waterman score: 2065; 43.7% identity (66.6% similar) in 885 aa overlap (11-826:12-843)
10 20 30 40 50
pF1KE2 MNIQEQGFPLDLGASFTEDAPRPPVPGEEGELVSTDP-RPASYSFCSGKGVGIKGETST
: ..:: :::::::::::::: : : .:. ::: : .
CCDS11 MSSAMLVTCLPDPSSSFREDAPRPPVPGEEGE---TPPCQPGV-----GKGQVTKPMPVS
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 ATPRRSDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFW
.. ::.. :: :::: ::: : .:..:::::: :::: ::::::..: :.: ::::
CCDS11 SNTRRNEDGLG-EPEGRASPDSPLTRWTKSLHSLLGDQDGAYLFRTFLEREKCVDTLDFW
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 FACTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLID
:::.:::... :. : :..:.:::..:: .::.:::.: :::::..:. : :: ::
CCDS11 FACNGFRQMNLKDT---KTLRVAKAIYKRYI-ENNSIVSKQLKPATKTYIRDGIKKQQID
120 130 140 150 160
180 190 200 210 220 230
pF1KE2 PAMFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGISGYL
::::::::::..::::.: :: :::::::.:.:.:. :. .: :. : . :::
CCDS11 SIMFDQAQTEIQSVMEENAYQMFLTSDIYLEYVRSGGENTAYMSN--GGLGSLKVVCGYL
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE2 PTLNEDEEWKCDQDMDEDDGRDAAPPGRL-PQKLLLETAAPRVSSSRRYSEGREFRYGSW
:::::.::: : : .: : . : . . :...: : .: . : :.
CCDS11 PTLNEEEEWTC-----------ADFKCKLSPTVVGLSSKTLRATASVRSTETVDSGYRSF
230 240 250 260 270
300 310 320 330 340 350
pF1KE2 R--EPVNPYYVNAGYALAPATSANDSEQQSLSSDA---DTLSLTDSSVDGIPPYRI--RK
. .:::::....::..:::::::::: .:::: :..:.::::::::::::. .:
CCDS11 KRSDPVNPYHIGSGYVFAPATSANDSE---ISSDALTDDSMSMTDSSVDGIPPYRVGSKK
280 290 300 310 320 330
360 370 380 390 400
pF1KE2 QHRREMQESVQVNGRVPLPHIPRTYRVPKEVR-VEPQKFAEELIHRLEAVQRTREAEEKL
: .:::..::..::.: :::.:::.:.:::. ::: :: ::: ::: .. :....:
CCDS11 QLQREMHRSVKANGQVSLPHFPRTHRLPKEMTPVEPATFAAELISRLEKLKLELESRHSL
340 350 360 370 380 390
410 420 430 440 450 460
pF1KE2 EERLKRVRMEEEGEDSDPSSGPPGPCHKLPPAPAWHHFPPRCVDMGCAGLRDAHEENPES
::::...: .:: : :. . .. ::. : : . : ..::.:..
CCDS11 EERLQQIREDEEREGSELT------LNSREGAPTQH--PLSLLPSG------SYEEDPQT
400 410 420 430
470 480 490 500 510
pF1KE2 ILDEHVQRVLRTPGRQSPG-----PGHRSPDSGHVAK------MPVA--LGGAASGHGKH
:::.:..:::.::: :::: : :::: : . .: . : ::.. :
CCDS11 ILDDHLSRVLKTPGCQSPGVGRYSPRSRSPDHHHHHHSQYHSLLPPGGKLPPAAASPGA-
440 450 460 470 480 490
520 530 540 550 560 570
pF1KE2 VPKSGAKLDAAGLHHHRHVHHHV--HHSTARPKEQVEAEATRRAQSSFAWGLEPHSHGAR
: :.: . . .::::: ::.. . ::..:::::.:.. : : . . ..
CCDS11 CPLLGGK-GFVTKQTTKHVHHHYIHHHAVPKTKEEIEAEATQRVHCFCPGGSEYYCY-SK
500 510 520 530 540 550
580 590 600 610 620
pF1KE2 SRGYSESVGAAPNASDGLAHSGKVGVAC-KRNAKKAESGKSASTE---VPGAS-------
...:.. . :. . : :. : . :::.: .: : . .. .::..
CCDS11 CKSHSKAPETMPSEQFG----GSRGSTLPKRNGKGTEPGLALPAREGGAPGGAGALQLPR
560 570 580 590 600 610
630 640 650 660 670
pF1KE2 EDAEKNQKIMQWIIEGEKEISRHRRTGHGSSGTRKPQPHENSR--P---LSLEHPWAGPQ
:.....: . ::..:.:.. :. . :....:.: : :..: : : .: :.: .
CCDS11 EEGDRSQDVWQWMLESERQ-SKPK--PHSAQSTKKAYPLESARSSPGERASRHHLWGGNS
620 630 640 650 660
680 690 700 710 720 730
pF1KE2 LRTSVQP-SHLFIQDPTMPPHPAPNPLTQLEEARRRLEEEEKRASR---APSKQRTRSQ-
. . : .::: :::.::: :: :.::::: ::: : : .. . :.:: :..
CCDS11 GHPRTTPRAHLFTQDPAMPPLTPPNTLAQLEEACRRLAEVSKPPKQRCCVASQQRDRNHS
670 680 690 700 710 720
740 750 760 770
pF1KE2 -----------------------RKVGGGSAQPCDSIVVAYYFCGEPIPYRTLVRGRAVT
.:..: : . .::.:.:::: :::: .......:
CCDS11 ATVQTGATPFSNPSLAPEDHKEPKKLAGVHALQASELVVTYFFCGEEIPYRRMLKAQSLT
730 740 750 760 770 780
780 790 800 810 820
pF1KE2 LGQFKELLTKKGSYRYYFKKVSDEFDCGVVFEEVREDEAVLPVFEEKIIGKVEKVD
::.::: :.:::.:::::::.:::: ::.::::. :::.:::..: .:.::::..:
CCDS11 LGHFKEQLSKKGNYRYYFKKASDEFACGAVFEEIWEDETVLPMYEGRILGKVERID
790 800 810 820 830 840
826 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 05:46:50 2016 done: Sun Nov 6 05:46:51 2016
Total Scan time: 4.970 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]