Result of FASTA (omim) for
pFN21AE2100
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2100, 189 aa
1>>>pF1KE2100 189 - 189 aa - 189 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2371+/-0.000369; mu= 13.1644+/- 0.023
mean_var=62.1155+/-12.487, 0's: 0 Z-trim(112.6): 18 B-trim: 36 in 1/52
Lambda= 0.162732
statistics sampled from 21511 (21528) to 21511 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.64), E-opt: 0.2 (0.252), width: 16
Scan time: 4.700
The best scores are: opt bits E(85289)
NP_066546 (OMIM: 147564) interferon alpha-4 precur ( 189) 1230 297.2 1.1e-80
NP_067091 (OMIM: 147583) interferon alpha-17 precu ( 189) 1182 285.9 2.6e-77
NP_002162 (OMIM: 147577) interferon alpha-10 precu ( 189) 1172 283.6 1.3e-76
NP_066401 (OMIM: 147567) interferon alpha-7 precur ( 189) 1149 278.2 5.6e-75
NP_002166 (OMIM: 147584) interferon alpha-21 precu ( 189) 1130 273.7 1.2e-73
NP_002164 (OMIM: 147580) interferon alpha-16 precu ( 189) 1101 266.9 1.4e-71
NP_002160 (OMIM: 147565) interferon alpha-5 precur ( 189) 1063 258.0 6.7e-69
NP_002163 (OMIM: 147579) interferon alpha-14 precu ( 189) 1054 255.9 2.9e-68
NP_000596 (OMIM: 147562) interferon alpha-2 precur ( 188) 1002 243.6 1.4e-64
NP_066282 (OMIM: 147566) interferon alpha-6 precur ( 189) 1002 243.7 1.4e-64
NP_008831 (OMIM: 147578) interferon alpha-1/13 pre ( 190) 995 242.0 4.3e-64
NP_076918 (OMIM: 147660) interferon alpha-1/13 pre ( 189) 990 240.8 9.7e-64
NP_002161 (OMIM: 147568) interferon alpha-8 precur ( 189) 988 240.4 1.3e-63
NP_002168 (OMIM: 147553) interferon omega-1 precur ( 195) 704 173.7 1.6e-43
NP_795372 (OMIM: 615223) interferon epsilon precur ( 208) 355 91.8 7.9e-19
NP_002167 (OMIM: 147640) interferon beta precursor ( 187) 335 87.1 1.9e-17
NP_064509 (OMIM: 615326) interferon kappa precurso ( 207) 168 47.9 1.3e-05
>>NP_066546 (OMIM: 147564) interferon alpha-4 precursor (189 aa)
initn: 1230 init1: 1230 opt: 1230 Z-score: 1569.8 bits: 297.2 E(85289): 1.1e-80
Smith-Waterman score: 1230; 99.5% identity (100.0% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE2 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRHDFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 FPEEEFDGHQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
:::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::
NP_066 FPEEEFDGHQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KE2 LQKRLRRKD
:::::::::
NP_066 LQKRLRRKD
>>NP_067091 (OMIM: 147583) interferon alpha-17 precursor (189 aa)
initn: 1182 init1: 1182 opt: 1182 Z-score: 1508.9 bits: 285.9 E(85289): 2.6e-77
Smith-Waterman score: 1182; 96.3% identity (98.9% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE2 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRHDFG
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
NP_067 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 FPEEEFDGHQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
.:.:::::.::::::::::::::::::::::::::::::::::::::::::::::::.::
NP_067 LPQEEFDGNQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNNLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 ACVIQEVGMEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KE2 LQKRLRRKD
::: :::::
NP_067 LQKILRRKD
>>NP_002162 (OMIM: 147577) interferon alpha-10 precursor (189 aa)
initn: 1172 init1: 1172 opt: 1172 Z-score: 1496.3 bits: 283.6 E(85289): 1.3e-76
Smith-Waterman score: 1172; 95.2% identity (98.4% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE2 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRHDFG
:::::::::::::::::::::::::::::::::::::::::.:::::: ::::::::::
NP_002 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLGQMGRISPFSCLKDRHDFR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 FPEEEFDGHQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
.:.:::::.::::.::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
:::::::::::::::::::::::::::::::::: :.:::::::::::::::::::::::
NP_002 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLIERKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KE2 LQKRLRRKD
:::::::::
NP_002 LQKRLRRKD
>>NP_066401 (OMIM: 147567) interferon alpha-7 precursor (189 aa)
initn: 1149 init1: 1149 opt: 1149 Z-score: 1467.1 bits: 278.2 E(85289): 5.6e-75
Smith-Waterman score: 1149; 94.2% identity (96.3% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE2 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRHDFG
:: ::::::.:::::::::::::::::::::: ::::::::::::::: ::::::::.:
NP_066 MARSFSLLMVVLVLSYKSICSLGCDLPQTHSLRNRRALILLAQMGRISPFSCLKDRHEFR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 FPEEEFDGHQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 FPEEEFDGHQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
:::::::::::::::::: ::::::::::::::: :::::::::::::::::::.:::::
NP_066 ACVIQEVGVEETPLMNEDFILAVRKYFQRITLYLMEKKYSPCAWEVVRAEIMRSFSFSTN
130 140 150 160 170 180
pF1KE2 LQKRLRRKD
:.: :::::
NP_066 LKKGLRRKD
>>NP_002166 (OMIM: 147584) interferon alpha-21 precursor (189 aa)
initn: 1165 init1: 1130 opt: 1130 Z-score: 1443.0 bits: 273.7 E(85289): 1.2e-73
Smith-Waterman score: 1130; 91.5% identity (97.4% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE2 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRHDFG
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
NP_002 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 FPEEEFDGHQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
::.:::::.::::.:::::::::::::::::::.::::.::::::::::::: :::::::
NP_002 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWEQSLLEKFSTELNQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
:::::::::::::::: ::::::.::::::::::::::::::::::::::::::.:.:
NP_002 ACVIQEVGVEETPLMNVDSILAVKKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSKI
130 140 150 160 170 180
pF1KE2 LQKRLRRKD
.:.:::::.
NP_002 FQERLRRKE
>>NP_002164 (OMIM: 147580) interferon alpha-16 precursor (189 aa)
initn: 1101 init1: 1101 opt: 1101 Z-score: 1406.2 bits: 266.9 E(85289): 1.4e-71
Smith-Waterman score: 1101; 88.4% identity (95.2% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE2 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRHDFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
NP_002 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRYDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 FPEEEFDGHQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
::.: :::.::::.::::..:::::::::::::.::::::...::.:: ::.:::::::
NP_002 FPQEVFDGNQFQKAQAISAFHEMIQQTFNLFSTKDSSAAWDETLLDKFYIELFQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
::: ::::::: ::::::::::::::::::::: ::::::::::::::::::.:::::
NP_002 ACVTQEVGVEEIALMNEDSILAVRKYFQRITLYLMGKKYSPCAWEVVRAEIMRSFSFSTN
130 140 150 160 170 180
pF1KE2 LQKRLRRKD
::: :::::
NP_002 LQKGLRRKD
>>NP_002160 (OMIM: 147565) interferon alpha-5 precursor (189 aa)
initn: 1078 init1: 1063 opt: 1063 Z-score: 1358.0 bits: 258.0 E(85289): 6.7e-69
Smith-Waterman score: 1063; 83.1% identity (96.8% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE2 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRHDFG
::: : ::::..::. ::::::::::::::::.:::.:...::::::: :::::::::::
NP_002 MALPFVLLMALVVLNCKSICSLGCDLPQTHSLSNRRTLMIMAQMGRISPFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 FPEEEFDGHQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
::.:::::.::::.:::::::::::::::::::.::::.:...::.:: :::::::::::
NP_002 FPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSATWDETLLDKFYTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
::..::::::.::::: ::::.::::::::::::::::::::::::::::::::.:.:.:
NP_002 ACMMQEVGVEDTPLMNVDSILTVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSAN
130 140 150 160 170 180
pF1KE2 LQKRLRRKD
::.:::::.
NP_002 LQERLRRKE
>>NP_002163 (OMIM: 147579) interferon alpha-14 precursor (189 aa)
initn: 1054 init1: 1054 opt: 1054 Z-score: 1346.5 bits: 255.9 E(85289): 2.9e-68
Smith-Waterman score: 1054; 83.6% identity (94.7% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE2 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRHDFG
::: :.:.::..::: :: :::::.: :::::.:::.:.:.::: ::: ::::::::::
NP_002 MALPFALMMALVVLSCKSSCSLGCNLSQTHSLNNRRTLMLMAQMRRISPFSCLKDRHDFE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 FPEEEFDGHQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
::.:::::.::::.:::::::::.:::::::::..:::::...::::: ::.::.::::
NP_002 FPQEEFDGNQFQKAQAISVLHEMMQQTFNLFSTKNSSAAWDETLLEKFYIELFQQMNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
:::::::::::::::::::::::.:::::::::: :::::::::::::::::::::::::
NP_002 ACVIQEVGVEETPLMNEDSILAVKKYFQRITLYLMEKKYSPCAWEVVRAEIMRSLSFSTN
130 140 150 160 170 180
pF1KE2 LQKRLRRKD
:::::::::
NP_002 LQKRLRRKD
>>NP_000596 (OMIM: 147562) interferon alpha-2 precursor (188 aa)
initn: 1006 init1: 644 opt: 1002 Z-score: 1280.6 bits: 243.6 E(85289): 1.4e-64
Smith-Waterman score: 1002; 81.0% identity (93.1% similar) in 189 aa overlap (1-189:1-188)
10 20 30 40 50 60
pF1KE2 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRHDFG
:::.:.::.:.:::: :: ::.:::::::::::.::.:.::::: ::: :::::::::::
NP_000 MALTFALLVALLVLSCKSSCSVGCDLPQTHSLGSRRTLMLLAQMRRISLFSCLKDRHDFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 FPEEEFDGHQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
::.::: :.::::...: :::::::: ::::::.::::::...::.:: :::::::::::
NP_000 FPQEEF-GNQFQKAETIPVLHEMIQQIFNLFSTKDSSAAWDETLLDKFYTELYQQLNDLE
70 80 90 100 110
130 140 150 160 170 180
pF1KE2 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
::::: ::: :::::.:::::::::::::::::: :::::::::::::::::::.:.:::
NP_000 ACVIQGVGVTETPLMKEDSILAVRKYFQRITLYLKEKKYSPCAWEVVRAEIMRSFSLSTN
120 130 140 150 160 170
pF1KE2 LQKRLRRKD
::. :: :.
NP_000 LQESLRSKE
180
>>NP_066282 (OMIM: 147566) interferon alpha-6 precursor (189 aa)
initn: 1017 init1: 1002 opt: 1002 Z-score: 1280.6 bits: 243.7 E(85289): 1.4e-64
Smith-Waterman score: 1002; 81.0% identity (92.6% similar) in 189 aa overlap (1-189:1-189)
10 20 30 40 50 60
pF1KE2 MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRHDFG
::: :.::::..::: :: ::: ::::::::::.::...::::: ::: ::::::::::
NP_066 MALPFALLMALVVLSCKSSCSLDCDLPQTHSLGHRRTMMLLAQMRRISLFSCLKDRHDFR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 FPEEEFDGHQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLE
::.:::::.::::..:::::::.::::::::::.:::.::.. ::.:. :::::::::::
NP_066 FPQEEFDGNQFQKAEAISVLHEVIQQTFNLFSTKDSSVAWDERLLDKLYTELYQQLNDLE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 ACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTN
:::.::: : :::::::::::::::::::::::::::::::::::::::::::.: : :
NP_066 ACVMQEVWVGGTPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSSSRN
130 140 150 160 170 180
pF1KE2 LQKRLRRKD
::.:::::.
NP_066 LQERLRRKE
189 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 15:49:47 2016 done: Sun Nov 6 15:49:48 2016
Total Scan time: 4.700 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]