Result of FASTA (omim) for
pFN21AE2083
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2083, 757 aa
1>>>pF1KE2083 757 - 757 aa - 757 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.8457+/-0.000388; mu= 13.7040+/- 0.024
mean_var=121.8492+/-24.317, 0's: 0 Z-trim(115.4): 40 B-trim: 0 in 0/51
Lambda= 0.116188
statistics sampled from 25812 (25852) to 25812 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.665), E-opt: 0.2 (0.303), width: 16
Scan time: 12.380
The best scores are: opt bits E(85289)
XP_016884487 (OMIM: 614216) PREDICTED: activating ( 757) 5065 860.8 0
XP_016884488 (OMIM: 614216) PREDICTED: activating ( 757) 5065 860.8 0
XP_016884489 (OMIM: 614216) PREDICTED: activating ( 757) 5065 860.8 0
XP_005261832 (OMIM: 614216) PREDICTED: activating ( 757) 5065 860.8 0
NP_115580 (OMIM: 614216) activating signal cointeg ( 757) 5065 860.8 0
XP_016884481 (OMIM: 614216) PREDICTED: activating ( 811) 5065 860.8 0
XP_011528748 (OMIM: 614216) PREDICTED: activating ( 762) 5045 857.4 0
XP_016884485 (OMIM: 614216) PREDICTED: activating ( 762) 5045 857.4 0
XP_011528744 (OMIM: 614216) PREDICTED: activating ( 762) 5045 857.4 0
XP_011528746 (OMIM: 614216) PREDICTED: activating ( 762) 5045 857.4 0
XP_011528745 (OMIM: 614216) PREDICTED: activating ( 762) 5045 857.4 0
XP_011528747 (OMIM: 614216) PREDICTED: activating ( 762) 5045 857.4 0
XP_016884480 (OMIM: 614216) PREDICTED: activating ( 816) 5045 857.5 0
XP_016884492 (OMIM: 614216) PREDICTED: activating ( 704) 4499 765.9 0
XP_016884491 (OMIM: 614216) PREDICTED: activating ( 704) 4499 765.9 0
XP_016884490 (OMIM: 614216) PREDICTED: activating ( 704) 4499 765.9 0
XP_016884486 (OMIM: 614216) PREDICTED: activating ( 758) 4499 765.9 0
XP_011528751 (OMIM: 614216) PREDICTED: activating ( 709) 4479 762.5 0
XP_011528750 (OMIM: 614216) PREDICTED: activating ( 709) 4479 762.5 0
XP_016884484 (OMIM: 614216) PREDICTED: activating ( 763) 4479 762.6 0
XP_016884495 (OMIM: 614216) PREDICTED: activating ( 643) 4273 728.0 3e-209
XP_016884496 (OMIM: 614216) PREDICTED: activating ( 643) 4273 728.0 3e-209
XP_016884494 (OMIM: 614216) PREDICTED: activating ( 643) 4273 728.0 3e-209
XP_016884498 (OMIM: 614216) PREDICTED: activating ( 643) 4273 728.0 3e-209
XP_016884497 (OMIM: 614216) PREDICTED: activating ( 643) 4273 728.0 3e-209
XP_011528756 (OMIM: 614216) PREDICTED: activating ( 648) 4253 724.6 3e-208
XP_011528752 (OMIM: 614216) PREDICTED: activating ( 648) 4253 724.6 3e-208
XP_011528753 (OMIM: 614216) PREDICTED: activating ( 648) 4253 724.6 3e-208
XP_011528755 (OMIM: 614216) PREDICTED: activating ( 648) 4253 724.6 3e-208
XP_011528754 (OMIM: 614216) PREDICTED: activating ( 648) 4253 724.6 3e-208
XP_011528757 (OMIM: 614216) PREDICTED: activating ( 648) 4253 724.6 3e-208
NP_001229835 (OMIM: 614216) activating signal coin ( 681) 3972 677.6 4.8e-194
XP_016884493 (OMIM: 614216) PREDICTED: activating ( 679) 3006 515.6 2.6e-145
XP_016884483 (OMIM: 614216) PREDICTED: activating ( 786) 3006 515.7 3e-145
XP_016884482 (OMIM: 614216) PREDICTED: activating ( 791) 2986 512.3 3.1e-144
>>XP_016884487 (OMIM: 614216) PREDICTED: activating sign (757 aa)
initn: 5065 init1: 5065 opt: 5065 Z-score: 4594.3 bits: 860.8 E(85289): 0
Smith-Waterman score: 5065; 100.0% identity (100.0% similar) in 757 aa overlap (1-757:1-757)
10 20 30 40 50 60
pF1KE2 MPALPLDQLQITHKDPKTGKLRTSPALHPEQKADRYFVLYKPPPKDNIPALVEEYLERAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPALPLDQLQITHKDPKTGKLRTSPALHPEQKADRYFVLYKPPPKDNIPALVEEYLERAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 FVANDLDWLLALPHDKFWCQVIFDETLQKCLDSYLRYVPRKFDEGVASAPEVVDMQKRLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FVANDLDWLLALPHDKFWCQVIFDETLQKCLDSYLRYVPRKFDEGVASAPEVVDMQKRLH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 RSVFLTFLRMSTHKESKDHFISPSAFGEILYNNFLFDIPKILDLCVLFGKGNSPLLQKMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSVFLTFLRMSTHKESKDHFISPSAFGEILYNNFLFDIPKILDLCVLFGKGNSPLLQKMI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 GNIFTQQPSYYSDLDETLPTILQVFSNILQHCGLQGDGANTTPQKLEERGRLTPSDMPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNIFTQQPSYYSDLDETLPTILQVFSNILQHCGLQGDGANTTPQKLEERGRLTPSDMPLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 ELKDIVLYLCDTCTTLWAFLDIFPLACQTFQKHDFCYRLASFYEAAIPEMESAIKKRRLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELKDIVLYLCDTCTTLWAFLDIFPLACQTFQKHDFCYRLASFYEAAIPEMESAIKKRRLE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 DSKLLGDLWQRLSHSRKKLMEIFHIILNQICLLPILESSCDNIQGFIEEFLQIFSSLLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSKLLGDLWQRLSHSRKKLMEIFHIILNQICLLPILESSCDNIQGFIEEFLQIFSSLLQE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 KRFLRDYDALFPVAEDISLLQQASSVLDETRTAYILQAVESAWEGVDRRKATDAKDPSVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRFLRDYDALFPVAEDISLLQQASSVLDETRTAYILQAVESAWEGVDRRKATDAKDPSVI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 EEPNGEPNGVTVTAEAVSQASSHPENSEEEECMGAAAAVGPAMCGVELDSLISQVKDLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEPNGEPNGVTVTAEAVSQASSHPENSEEEECMGAAAAVGPAMCGVELDSLISQVKDLLP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 DLGEGFILACLEYYHYDPEQVINNILEERLAPTLSQLDRNLDREMKPDPTPLLTSRHNVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLGEGFILACLEYYHYDPEQVINNILEERLAPTLSQLDRNLDREMKPDPTPLLTSRHNVF
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 QNDEFDVFSRDSVDLSRVHKGKSTRKEENTRSLLNDKRAVAAQRQRYEQYSVVVEEVPLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNDEFDVFSRDSVDLSRVHKGKSTRKEENTRSLLNDKRAVAAQRQRYEQYSVVVEEVPLQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 PGESLPYHSVYYEDEYDDTYDGNQVGANDADSDDELISRRPFTIPQVLRTKVPREGQEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGESLPYHSVYYEDEYDDTYDGNQVGANDADSDDELISRRPFTIPQVLRTKVPREGQEED
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 DDDEEDDADEEAPKPDHFVQDPAVLREKAEARRMAFLAKKGYRHDSSTAVAGSPRGHGQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDDEEDDADEEAPKPDHFVQDPAVLREKAEARRMAFLAKKGYRHDSSTAVAGSPRGHGQS
670 680 690 700 710 720
730 740 750
pF1KE2 RETTQERRKKEANKATRANHNRRTMADRKRSKGMIPS
:::::::::::::::::::::::::::::::::::::
XP_016 RETTQERRKKEANKATRANHNRRTMADRKRSKGMIPS
730 740 750
>>XP_016884488 (OMIM: 614216) PREDICTED: activating sign (757 aa)
initn: 5065 init1: 5065 opt: 5065 Z-score: 4594.3 bits: 860.8 E(85289): 0
Smith-Waterman score: 5065; 100.0% identity (100.0% similar) in 757 aa overlap (1-757:1-757)
10 20 30 40 50 60
pF1KE2 MPALPLDQLQITHKDPKTGKLRTSPALHPEQKADRYFVLYKPPPKDNIPALVEEYLERAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPALPLDQLQITHKDPKTGKLRTSPALHPEQKADRYFVLYKPPPKDNIPALVEEYLERAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 FVANDLDWLLALPHDKFWCQVIFDETLQKCLDSYLRYVPRKFDEGVASAPEVVDMQKRLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FVANDLDWLLALPHDKFWCQVIFDETLQKCLDSYLRYVPRKFDEGVASAPEVVDMQKRLH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 RSVFLTFLRMSTHKESKDHFISPSAFGEILYNNFLFDIPKILDLCVLFGKGNSPLLQKMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSVFLTFLRMSTHKESKDHFISPSAFGEILYNNFLFDIPKILDLCVLFGKGNSPLLQKMI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 GNIFTQQPSYYSDLDETLPTILQVFSNILQHCGLQGDGANTTPQKLEERGRLTPSDMPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNIFTQQPSYYSDLDETLPTILQVFSNILQHCGLQGDGANTTPQKLEERGRLTPSDMPLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 ELKDIVLYLCDTCTTLWAFLDIFPLACQTFQKHDFCYRLASFYEAAIPEMESAIKKRRLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELKDIVLYLCDTCTTLWAFLDIFPLACQTFQKHDFCYRLASFYEAAIPEMESAIKKRRLE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 DSKLLGDLWQRLSHSRKKLMEIFHIILNQICLLPILESSCDNIQGFIEEFLQIFSSLLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSKLLGDLWQRLSHSRKKLMEIFHIILNQICLLPILESSCDNIQGFIEEFLQIFSSLLQE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 KRFLRDYDALFPVAEDISLLQQASSVLDETRTAYILQAVESAWEGVDRRKATDAKDPSVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRFLRDYDALFPVAEDISLLQQASSVLDETRTAYILQAVESAWEGVDRRKATDAKDPSVI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 EEPNGEPNGVTVTAEAVSQASSHPENSEEEECMGAAAAVGPAMCGVELDSLISQVKDLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEPNGEPNGVTVTAEAVSQASSHPENSEEEECMGAAAAVGPAMCGVELDSLISQVKDLLP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 DLGEGFILACLEYYHYDPEQVINNILEERLAPTLSQLDRNLDREMKPDPTPLLTSRHNVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLGEGFILACLEYYHYDPEQVINNILEERLAPTLSQLDRNLDREMKPDPTPLLTSRHNVF
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 QNDEFDVFSRDSVDLSRVHKGKSTRKEENTRSLLNDKRAVAAQRQRYEQYSVVVEEVPLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNDEFDVFSRDSVDLSRVHKGKSTRKEENTRSLLNDKRAVAAQRQRYEQYSVVVEEVPLQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 PGESLPYHSVYYEDEYDDTYDGNQVGANDADSDDELISRRPFTIPQVLRTKVPREGQEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGESLPYHSVYYEDEYDDTYDGNQVGANDADSDDELISRRPFTIPQVLRTKVPREGQEED
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 DDDEEDDADEEAPKPDHFVQDPAVLREKAEARRMAFLAKKGYRHDSSTAVAGSPRGHGQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDDEEDDADEEAPKPDHFVQDPAVLREKAEARRMAFLAKKGYRHDSSTAVAGSPRGHGQS
670 680 690 700 710 720
730 740 750
pF1KE2 RETTQERRKKEANKATRANHNRRTMADRKRSKGMIPS
:::::::::::::::::::::::::::::::::::::
XP_016 RETTQERRKKEANKATRANHNRRTMADRKRSKGMIPS
730 740 750
>>XP_016884489 (OMIM: 614216) PREDICTED: activating sign (757 aa)
initn: 5065 init1: 5065 opt: 5065 Z-score: 4594.3 bits: 860.8 E(85289): 0
Smith-Waterman score: 5065; 100.0% identity (100.0% similar) in 757 aa overlap (1-757:1-757)
10 20 30 40 50 60
pF1KE2 MPALPLDQLQITHKDPKTGKLRTSPALHPEQKADRYFVLYKPPPKDNIPALVEEYLERAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPALPLDQLQITHKDPKTGKLRTSPALHPEQKADRYFVLYKPPPKDNIPALVEEYLERAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 FVANDLDWLLALPHDKFWCQVIFDETLQKCLDSYLRYVPRKFDEGVASAPEVVDMQKRLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FVANDLDWLLALPHDKFWCQVIFDETLQKCLDSYLRYVPRKFDEGVASAPEVVDMQKRLH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 RSVFLTFLRMSTHKESKDHFISPSAFGEILYNNFLFDIPKILDLCVLFGKGNSPLLQKMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSVFLTFLRMSTHKESKDHFISPSAFGEILYNNFLFDIPKILDLCVLFGKGNSPLLQKMI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 GNIFTQQPSYYSDLDETLPTILQVFSNILQHCGLQGDGANTTPQKLEERGRLTPSDMPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNIFTQQPSYYSDLDETLPTILQVFSNILQHCGLQGDGANTTPQKLEERGRLTPSDMPLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 ELKDIVLYLCDTCTTLWAFLDIFPLACQTFQKHDFCYRLASFYEAAIPEMESAIKKRRLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELKDIVLYLCDTCTTLWAFLDIFPLACQTFQKHDFCYRLASFYEAAIPEMESAIKKRRLE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 DSKLLGDLWQRLSHSRKKLMEIFHIILNQICLLPILESSCDNIQGFIEEFLQIFSSLLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSKLLGDLWQRLSHSRKKLMEIFHIILNQICLLPILESSCDNIQGFIEEFLQIFSSLLQE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 KRFLRDYDALFPVAEDISLLQQASSVLDETRTAYILQAVESAWEGVDRRKATDAKDPSVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRFLRDYDALFPVAEDISLLQQASSVLDETRTAYILQAVESAWEGVDRRKATDAKDPSVI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 EEPNGEPNGVTVTAEAVSQASSHPENSEEEECMGAAAAVGPAMCGVELDSLISQVKDLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEPNGEPNGVTVTAEAVSQASSHPENSEEEECMGAAAAVGPAMCGVELDSLISQVKDLLP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 DLGEGFILACLEYYHYDPEQVINNILEERLAPTLSQLDRNLDREMKPDPTPLLTSRHNVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLGEGFILACLEYYHYDPEQVINNILEERLAPTLSQLDRNLDREMKPDPTPLLTSRHNVF
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 QNDEFDVFSRDSVDLSRVHKGKSTRKEENTRSLLNDKRAVAAQRQRYEQYSVVVEEVPLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNDEFDVFSRDSVDLSRVHKGKSTRKEENTRSLLNDKRAVAAQRQRYEQYSVVVEEVPLQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 PGESLPYHSVYYEDEYDDTYDGNQVGANDADSDDELISRRPFTIPQVLRTKVPREGQEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGESLPYHSVYYEDEYDDTYDGNQVGANDADSDDELISRRPFTIPQVLRTKVPREGQEED
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 DDDEEDDADEEAPKPDHFVQDPAVLREKAEARRMAFLAKKGYRHDSSTAVAGSPRGHGQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDDEEDDADEEAPKPDHFVQDPAVLREKAEARRMAFLAKKGYRHDSSTAVAGSPRGHGQS
670 680 690 700 710 720
730 740 750
pF1KE2 RETTQERRKKEANKATRANHNRRTMADRKRSKGMIPS
:::::::::::::::::::::::::::::::::::::
XP_016 RETTQERRKKEANKATRANHNRRTMADRKRSKGMIPS
730 740 750
>>XP_005261832 (OMIM: 614216) PREDICTED: activating sign (757 aa)
initn: 5065 init1: 5065 opt: 5065 Z-score: 4594.3 bits: 860.8 E(85289): 0
Smith-Waterman score: 5065; 100.0% identity (100.0% similar) in 757 aa overlap (1-757:1-757)
10 20 30 40 50 60
pF1KE2 MPALPLDQLQITHKDPKTGKLRTSPALHPEQKADRYFVLYKPPPKDNIPALVEEYLERAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MPALPLDQLQITHKDPKTGKLRTSPALHPEQKADRYFVLYKPPPKDNIPALVEEYLERAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 FVANDLDWLLALPHDKFWCQVIFDETLQKCLDSYLRYVPRKFDEGVASAPEVVDMQKRLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FVANDLDWLLALPHDKFWCQVIFDETLQKCLDSYLRYVPRKFDEGVASAPEVVDMQKRLH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 RSVFLTFLRMSTHKESKDHFISPSAFGEILYNNFLFDIPKILDLCVLFGKGNSPLLQKMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSVFLTFLRMSTHKESKDHFISPSAFGEILYNNFLFDIPKILDLCVLFGKGNSPLLQKMI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 GNIFTQQPSYYSDLDETLPTILQVFSNILQHCGLQGDGANTTPQKLEERGRLTPSDMPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GNIFTQQPSYYSDLDETLPTILQVFSNILQHCGLQGDGANTTPQKLEERGRLTPSDMPLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 ELKDIVLYLCDTCTTLWAFLDIFPLACQTFQKHDFCYRLASFYEAAIPEMESAIKKRRLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELKDIVLYLCDTCTTLWAFLDIFPLACQTFQKHDFCYRLASFYEAAIPEMESAIKKRRLE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 DSKLLGDLWQRLSHSRKKLMEIFHIILNQICLLPILESSCDNIQGFIEEFLQIFSSLLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSKLLGDLWQRLSHSRKKLMEIFHIILNQICLLPILESSCDNIQGFIEEFLQIFSSLLQE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 KRFLRDYDALFPVAEDISLLQQASSVLDETRTAYILQAVESAWEGVDRRKATDAKDPSVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KRFLRDYDALFPVAEDISLLQQASSVLDETRTAYILQAVESAWEGVDRRKATDAKDPSVI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 EEPNGEPNGVTVTAEAVSQASSHPENSEEEECMGAAAAVGPAMCGVELDSLISQVKDLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEPNGEPNGVTVTAEAVSQASSHPENSEEEECMGAAAAVGPAMCGVELDSLISQVKDLLP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 DLGEGFILACLEYYHYDPEQVINNILEERLAPTLSQLDRNLDREMKPDPTPLLTSRHNVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLGEGFILACLEYYHYDPEQVINNILEERLAPTLSQLDRNLDREMKPDPTPLLTSRHNVF
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 QNDEFDVFSRDSVDLSRVHKGKSTRKEENTRSLLNDKRAVAAQRQRYEQYSVVVEEVPLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QNDEFDVFSRDSVDLSRVHKGKSTRKEENTRSLLNDKRAVAAQRQRYEQYSVVVEEVPLQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 PGESLPYHSVYYEDEYDDTYDGNQVGANDADSDDELISRRPFTIPQVLRTKVPREGQEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGESLPYHSVYYEDEYDDTYDGNQVGANDADSDDELISRRPFTIPQVLRTKVPREGQEED
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 DDDEEDDADEEAPKPDHFVQDPAVLREKAEARRMAFLAKKGYRHDSSTAVAGSPRGHGQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DDDEEDDADEEAPKPDHFVQDPAVLREKAEARRMAFLAKKGYRHDSSTAVAGSPRGHGQS
670 680 690 700 710 720
730 740 750
pF1KE2 RETTQERRKKEANKATRANHNRRTMADRKRSKGMIPS
:::::::::::::::::::::::::::::::::::::
XP_005 RETTQERRKKEANKATRANHNRRTMADRKRSKGMIPS
730 740 750
>>NP_115580 (OMIM: 614216) activating signal cointegrato (757 aa)
initn: 5065 init1: 5065 opt: 5065 Z-score: 4594.3 bits: 860.8 E(85289): 0
Smith-Waterman score: 5065; 100.0% identity (100.0% similar) in 757 aa overlap (1-757:1-757)
10 20 30 40 50 60
pF1KE2 MPALPLDQLQITHKDPKTGKLRTSPALHPEQKADRYFVLYKPPPKDNIPALVEEYLERAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 MPALPLDQLQITHKDPKTGKLRTSPALHPEQKADRYFVLYKPPPKDNIPALVEEYLERAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 FVANDLDWLLALPHDKFWCQVIFDETLQKCLDSYLRYVPRKFDEGVASAPEVVDMQKRLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 FVANDLDWLLALPHDKFWCQVIFDETLQKCLDSYLRYVPRKFDEGVASAPEVVDMQKRLH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 RSVFLTFLRMSTHKESKDHFISPSAFGEILYNNFLFDIPKILDLCVLFGKGNSPLLQKMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 RSVFLTFLRMSTHKESKDHFISPSAFGEILYNNFLFDIPKILDLCVLFGKGNSPLLQKMI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 GNIFTQQPSYYSDLDETLPTILQVFSNILQHCGLQGDGANTTPQKLEERGRLTPSDMPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 GNIFTQQPSYYSDLDETLPTILQVFSNILQHCGLQGDGANTTPQKLEERGRLTPSDMPLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 ELKDIVLYLCDTCTTLWAFLDIFPLACQTFQKHDFCYRLASFYEAAIPEMESAIKKRRLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 ELKDIVLYLCDTCTTLWAFLDIFPLACQTFQKHDFCYRLASFYEAAIPEMESAIKKRRLE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 DSKLLGDLWQRLSHSRKKLMEIFHIILNQICLLPILESSCDNIQGFIEEFLQIFSSLLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 DSKLLGDLWQRLSHSRKKLMEIFHIILNQICLLPILESSCDNIQGFIEEFLQIFSSLLQE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 KRFLRDYDALFPVAEDISLLQQASSVLDETRTAYILQAVESAWEGVDRRKATDAKDPSVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 KRFLRDYDALFPVAEDISLLQQASSVLDETRTAYILQAVESAWEGVDRRKATDAKDPSVI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 EEPNGEPNGVTVTAEAVSQASSHPENSEEEECMGAAAAVGPAMCGVELDSLISQVKDLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 EEPNGEPNGVTVTAEAVSQASSHPENSEEEECMGAAAAVGPAMCGVELDSLISQVKDLLP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 DLGEGFILACLEYYHYDPEQVINNILEERLAPTLSQLDRNLDREMKPDPTPLLTSRHNVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 DLGEGFILACLEYYHYDPEQVINNILEERLAPTLSQLDRNLDREMKPDPTPLLTSRHNVF
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 QNDEFDVFSRDSVDLSRVHKGKSTRKEENTRSLLNDKRAVAAQRQRYEQYSVVVEEVPLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 QNDEFDVFSRDSVDLSRVHKGKSTRKEENTRSLLNDKRAVAAQRQRYEQYSVVVEEVPLQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 PGESLPYHSVYYEDEYDDTYDGNQVGANDADSDDELISRRPFTIPQVLRTKVPREGQEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 PGESLPYHSVYYEDEYDDTYDGNQVGANDADSDDELISRRPFTIPQVLRTKVPREGQEED
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 DDDEEDDADEEAPKPDHFVQDPAVLREKAEARRMAFLAKKGYRHDSSTAVAGSPRGHGQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 DDDEEDDADEEAPKPDHFVQDPAVLREKAEARRMAFLAKKGYRHDSSTAVAGSPRGHGQS
670 680 690 700 710 720
730 740 750
pF1KE2 RETTQERRKKEANKATRANHNRRTMADRKRSKGMIPS
:::::::::::::::::::::::::::::::::::::
NP_115 RETTQERRKKEANKATRANHNRRTMADRKRSKGMIPS
730 740 750
>>XP_016884481 (OMIM: 614216) PREDICTED: activating sign (811 aa)
initn: 5065 init1: 5065 opt: 5065 Z-score: 4593.8 bits: 860.8 E(85289): 0
Smith-Waterman score: 5065; 100.0% identity (100.0% similar) in 757 aa overlap (1-757:55-811)
10 20 30
pF1KE2 MPALPLDQLQITHKDPKTGKLRTSPALHPE
::::::::::::::::::::::::::::::
XP_016 SAPEQALPPGVCVSALFFPSIFLSGGSRSTMPALPLDQLQITHKDPKTGKLRTSPALHPE
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE2 QKADRYFVLYKPPPKDNIPALVEEYLERATFVANDLDWLLALPHDKFWCQVIFDETLQKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKADRYFVLYKPPPKDNIPALVEEYLERATFVANDLDWLLALPHDKFWCQVIFDETLQKC
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE2 LDSYLRYVPRKFDEGVASAPEVVDMQKRLHRSVFLTFLRMSTHKESKDHFISPSAFGEIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDSYLRYVPRKFDEGVASAPEVVDMQKRLHRSVFLTFLRMSTHKESKDHFISPSAFGEIL
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE2 YNNFLFDIPKILDLCVLFGKGNSPLLQKMIGNIFTQQPSYYSDLDETLPTILQVFSNILQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YNNFLFDIPKILDLCVLFGKGNSPLLQKMIGNIFTQQPSYYSDLDETLPTILQVFSNILQ
210 220 230 240 250 260
220 230 240 250 260 270
pF1KE2 HCGLQGDGANTTPQKLEERGRLTPSDMPLLELKDIVLYLCDTCTTLWAFLDIFPLACQTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HCGLQGDGANTTPQKLEERGRLTPSDMPLLELKDIVLYLCDTCTTLWAFLDIFPLACQTF
270 280 290 300 310 320
280 290 300 310 320 330
pF1KE2 QKHDFCYRLASFYEAAIPEMESAIKKRRLEDSKLLGDLWQRLSHSRKKLMEIFHIILNQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKHDFCYRLASFYEAAIPEMESAIKKRRLEDSKLLGDLWQRLSHSRKKLMEIFHIILNQI
330 340 350 360 370 380
340 350 360 370 380 390
pF1KE2 CLLPILESSCDNIQGFIEEFLQIFSSLLQEKRFLRDYDALFPVAEDISLLQQASSVLDET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLLPILESSCDNIQGFIEEFLQIFSSLLQEKRFLRDYDALFPVAEDISLLQQASSVLDET
390 400 410 420 430 440
400 410 420 430 440 450
pF1KE2 RTAYILQAVESAWEGVDRRKATDAKDPSVIEEPNGEPNGVTVTAEAVSQASSHPENSEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTAYILQAVESAWEGVDRRKATDAKDPSVIEEPNGEPNGVTVTAEAVSQASSHPENSEEE
450 460 470 480 490 500
460 470 480 490 500 510
pF1KE2 ECMGAAAAVGPAMCGVELDSLISQVKDLLPDLGEGFILACLEYYHYDPEQVINNILEERL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ECMGAAAAVGPAMCGVELDSLISQVKDLLPDLGEGFILACLEYYHYDPEQVINNILEERL
510 520 530 540 550 560
520 530 540 550 560 570
pF1KE2 APTLSQLDRNLDREMKPDPTPLLTSRHNVFQNDEFDVFSRDSVDLSRVHKGKSTRKEENT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APTLSQLDRNLDREMKPDPTPLLTSRHNVFQNDEFDVFSRDSVDLSRVHKGKSTRKEENT
570 580 590 600 610 620
580 590 600 610 620 630
pF1KE2 RSLLNDKRAVAAQRQRYEQYSVVVEEVPLQPGESLPYHSVYYEDEYDDTYDGNQVGANDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSLLNDKRAVAAQRQRYEQYSVVVEEVPLQPGESLPYHSVYYEDEYDDTYDGNQVGANDA
630 640 650 660 670 680
640 650 660 670 680 690
pF1KE2 DSDDELISRRPFTIPQVLRTKVPREGQEEDDDDEEDDADEEAPKPDHFVQDPAVLREKAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSDDELISRRPFTIPQVLRTKVPREGQEEDDDDEEDDADEEAPKPDHFVQDPAVLREKAE
690 700 710 720 730 740
700 710 720 730 740 750
pF1KE2 ARRMAFLAKKGYRHDSSTAVAGSPRGHGQSRETTQERRKKEANKATRANHNRRTMADRKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARRMAFLAKKGYRHDSSTAVAGSPRGHGQSRETTQERRKKEANKATRANHNRRTMADRKR
750 760 770 780 790 800
pF1KE2 SKGMIPS
:::::::
XP_016 SKGMIPS
810
>>XP_011528748 (OMIM: 614216) PREDICTED: activating sign (762 aa)
initn: 4517 init1: 4517 opt: 5045 Z-score: 4576.1 bits: 857.4 E(85289): 0
Smith-Waterman score: 5045; 99.3% identity (99.3% similar) in 762 aa overlap (1-757:1-762)
10 20 30 40 50 60
pF1KE2 MPALPLDQLQITHKDPKTGKLRTSPALHPEQKADRYFVLYKPPPKDNIPALVEEYLERAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPALPLDQLQITHKDPKTGKLRTSPALHPEQKADRYFVLYKPPPKDNIPALVEEYLERAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 FVANDLDWLLALPHDKFWCQVIFDETLQKCLDSYLRYVPRKFDEGVASAPEVVDMQKRLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FVANDLDWLLALPHDKFWCQVIFDETLQKCLDSYLRYVPRKFDEGVASAPEVVDMQKRLH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 RSVFLTFLRMSTHKESKDHFISPSAFGEILYNNFLFDIPKILDLCVLFGKGNSPLLQKMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSVFLTFLRMSTHKESKDHFISPSAFGEILYNNFLFDIPKILDLCVLFGKGNSPLLQKMI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 GNIFTQQPSYYSDLDETLPTILQVFSNILQHCGLQGDGANTTPQKLEERGRLTPSDMPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNIFTQQPSYYSDLDETLPTILQVFSNILQHCGLQGDGANTTPQKLEERGRLTPSDMPLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 ELKDIVLYLCDTCTTLWAFLDIFPLACQTFQKHDFCYRLASFYEAAIPEMESAIKKRRLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELKDIVLYLCDTCTTLWAFLDIFPLACQTFQKHDFCYRLASFYEAAIPEMESAIKKRRLE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 DSKLLGDLWQRLSHSRKKLMEIFHIILNQICLLPILESSCDNIQGFIEEFLQIFSSLLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSKLLGDLWQRLSHSRKKLMEIFHIILNQICLLPILESSCDNIQGFIEEFLQIFSSLLQE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 KRFLRDYDALFPVAEDISLLQQASSVLDETRTAYILQAVESAWEGVDRRKATDAKDPSVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRFLRDYDALFPVAEDISLLQQASSVLDETRTAYILQAVESAWEGVDRRKATDAKDPSVI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 EEPNGEPNGVTVTAEAVSQASSHPENSEEEECMGAAAAVGPAMCGVELDSLISQVKDLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEPNGEPNGVTVTAEAVSQASSHPENSEEEECMGAAAAVGPAMCGVELDSLISQVKDLLP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 DLGEGFILACLEYYHYDPEQVINNILEERLAPTLSQLDRNLDREMKPDPTPLLTSRHNVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLGEGFILACLEYYHYDPEQVINNILEERLAPTLSQLDRNLDREMKPDPTPLLTSRHNVF
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 QNDEFDVFSRDSVDLSRVHKGKSTRKEENTRSLLNDKRAVAAQRQRYEQYSVVVEEVPLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNDEFDVFSRDSVDLSRVHKGKSTRKEENTRSLLNDKRAVAAQRQRYEQYSVVVEEVPLQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 PGESLPYHSVYYEDEYDDTYDGNQVGANDADSDDELISRRPFTIPQVLRTKVPREGQEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGESLPYHSVYYEDEYDDTYDGNQVGANDADSDDELISRRPFTIPQVLRTKVPREGQEED
610 620 630 640 650 660
670 680 690 700 710
pF1KE2 DDDEEDDADEEAPK-----PDHFVQDPAVLREKAEARRMAFLAKKGYRHDSSTAVAGSPR
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_011 DDDEEDDADEEAPKVPPWQPDHFVQDPAVLREKAEARRMAFLAKKGYRHDSSTAVAGSPR
670 680 690 700 710 720
720 730 740 750
pF1KE2 GHGQSRETTQERRKKEANKATRANHNRRTMADRKRSKGMIPS
::::::::::::::::::::::::::::::::::::::::::
XP_011 GHGQSRETTQERRKKEANKATRANHNRRTMADRKRSKGMIPS
730 740 750 760
>>XP_016884485 (OMIM: 614216) PREDICTED: activating sign (762 aa)
initn: 4517 init1: 4517 opt: 5045 Z-score: 4576.1 bits: 857.4 E(85289): 0
Smith-Waterman score: 5045; 99.3% identity (99.3% similar) in 762 aa overlap (1-757:1-762)
10 20 30 40 50 60
pF1KE2 MPALPLDQLQITHKDPKTGKLRTSPALHPEQKADRYFVLYKPPPKDNIPALVEEYLERAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPALPLDQLQITHKDPKTGKLRTSPALHPEQKADRYFVLYKPPPKDNIPALVEEYLERAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 FVANDLDWLLALPHDKFWCQVIFDETLQKCLDSYLRYVPRKFDEGVASAPEVVDMQKRLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FVANDLDWLLALPHDKFWCQVIFDETLQKCLDSYLRYVPRKFDEGVASAPEVVDMQKRLH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 RSVFLTFLRMSTHKESKDHFISPSAFGEILYNNFLFDIPKILDLCVLFGKGNSPLLQKMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSVFLTFLRMSTHKESKDHFISPSAFGEILYNNFLFDIPKILDLCVLFGKGNSPLLQKMI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 GNIFTQQPSYYSDLDETLPTILQVFSNILQHCGLQGDGANTTPQKLEERGRLTPSDMPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNIFTQQPSYYSDLDETLPTILQVFSNILQHCGLQGDGANTTPQKLEERGRLTPSDMPLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 ELKDIVLYLCDTCTTLWAFLDIFPLACQTFQKHDFCYRLASFYEAAIPEMESAIKKRRLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELKDIVLYLCDTCTTLWAFLDIFPLACQTFQKHDFCYRLASFYEAAIPEMESAIKKRRLE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 DSKLLGDLWQRLSHSRKKLMEIFHIILNQICLLPILESSCDNIQGFIEEFLQIFSSLLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSKLLGDLWQRLSHSRKKLMEIFHIILNQICLLPILESSCDNIQGFIEEFLQIFSSLLQE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 KRFLRDYDALFPVAEDISLLQQASSVLDETRTAYILQAVESAWEGVDRRKATDAKDPSVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRFLRDYDALFPVAEDISLLQQASSVLDETRTAYILQAVESAWEGVDRRKATDAKDPSVI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 EEPNGEPNGVTVTAEAVSQASSHPENSEEEECMGAAAAVGPAMCGVELDSLISQVKDLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEPNGEPNGVTVTAEAVSQASSHPENSEEEECMGAAAAVGPAMCGVELDSLISQVKDLLP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 DLGEGFILACLEYYHYDPEQVINNILEERLAPTLSQLDRNLDREMKPDPTPLLTSRHNVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLGEGFILACLEYYHYDPEQVINNILEERLAPTLSQLDRNLDREMKPDPTPLLTSRHNVF
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 QNDEFDVFSRDSVDLSRVHKGKSTRKEENTRSLLNDKRAVAAQRQRYEQYSVVVEEVPLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNDEFDVFSRDSVDLSRVHKGKSTRKEENTRSLLNDKRAVAAQRQRYEQYSVVVEEVPLQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 PGESLPYHSVYYEDEYDDTYDGNQVGANDADSDDELISRRPFTIPQVLRTKVPREGQEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGESLPYHSVYYEDEYDDTYDGNQVGANDADSDDELISRRPFTIPQVLRTKVPREGQEED
610 620 630 640 650 660
670 680 690 700 710
pF1KE2 DDDEEDDADEEAPK-----PDHFVQDPAVLREKAEARRMAFLAKKGYRHDSSTAVAGSPR
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_016 DDDEEDDADEEAPKVPPWQPDHFVQDPAVLREKAEARRMAFLAKKGYRHDSSTAVAGSPR
670 680 690 700 710 720
720 730 740 750
pF1KE2 GHGQSRETTQERRKKEANKATRANHNRRTMADRKRSKGMIPS
::::::::::::::::::::::::::::::::::::::::::
XP_016 GHGQSRETTQERRKKEANKATRANHNRRTMADRKRSKGMIPS
730 740 750 760
>>XP_011528744 (OMIM: 614216) PREDICTED: activating sign (762 aa)
initn: 4517 init1: 4517 opt: 5045 Z-score: 4576.1 bits: 857.4 E(85289): 0
Smith-Waterman score: 5045; 99.3% identity (99.3% similar) in 762 aa overlap (1-757:1-762)
10 20 30 40 50 60
pF1KE2 MPALPLDQLQITHKDPKTGKLRTSPALHPEQKADRYFVLYKPPPKDNIPALVEEYLERAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPALPLDQLQITHKDPKTGKLRTSPALHPEQKADRYFVLYKPPPKDNIPALVEEYLERAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 FVANDLDWLLALPHDKFWCQVIFDETLQKCLDSYLRYVPRKFDEGVASAPEVVDMQKRLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FVANDLDWLLALPHDKFWCQVIFDETLQKCLDSYLRYVPRKFDEGVASAPEVVDMQKRLH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 RSVFLTFLRMSTHKESKDHFISPSAFGEILYNNFLFDIPKILDLCVLFGKGNSPLLQKMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSVFLTFLRMSTHKESKDHFISPSAFGEILYNNFLFDIPKILDLCVLFGKGNSPLLQKMI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 GNIFTQQPSYYSDLDETLPTILQVFSNILQHCGLQGDGANTTPQKLEERGRLTPSDMPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNIFTQQPSYYSDLDETLPTILQVFSNILQHCGLQGDGANTTPQKLEERGRLTPSDMPLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 ELKDIVLYLCDTCTTLWAFLDIFPLACQTFQKHDFCYRLASFYEAAIPEMESAIKKRRLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELKDIVLYLCDTCTTLWAFLDIFPLACQTFQKHDFCYRLASFYEAAIPEMESAIKKRRLE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 DSKLLGDLWQRLSHSRKKLMEIFHIILNQICLLPILESSCDNIQGFIEEFLQIFSSLLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSKLLGDLWQRLSHSRKKLMEIFHIILNQICLLPILESSCDNIQGFIEEFLQIFSSLLQE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 KRFLRDYDALFPVAEDISLLQQASSVLDETRTAYILQAVESAWEGVDRRKATDAKDPSVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRFLRDYDALFPVAEDISLLQQASSVLDETRTAYILQAVESAWEGVDRRKATDAKDPSVI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 EEPNGEPNGVTVTAEAVSQASSHPENSEEEECMGAAAAVGPAMCGVELDSLISQVKDLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEPNGEPNGVTVTAEAVSQASSHPENSEEEECMGAAAAVGPAMCGVELDSLISQVKDLLP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 DLGEGFILACLEYYHYDPEQVINNILEERLAPTLSQLDRNLDREMKPDPTPLLTSRHNVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLGEGFILACLEYYHYDPEQVINNILEERLAPTLSQLDRNLDREMKPDPTPLLTSRHNVF
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 QNDEFDVFSRDSVDLSRVHKGKSTRKEENTRSLLNDKRAVAAQRQRYEQYSVVVEEVPLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNDEFDVFSRDSVDLSRVHKGKSTRKEENTRSLLNDKRAVAAQRQRYEQYSVVVEEVPLQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 PGESLPYHSVYYEDEYDDTYDGNQVGANDADSDDELISRRPFTIPQVLRTKVPREGQEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGESLPYHSVYYEDEYDDTYDGNQVGANDADSDDELISRRPFTIPQVLRTKVPREGQEED
610 620 630 640 650 660
670 680 690 700 710
pF1KE2 DDDEEDDADEEAPK-----PDHFVQDPAVLREKAEARRMAFLAKKGYRHDSSTAVAGSPR
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_011 DDDEEDDADEEAPKVPPWQPDHFVQDPAVLREKAEARRMAFLAKKGYRHDSSTAVAGSPR
670 680 690 700 710 720
720 730 740 750
pF1KE2 GHGQSRETTQERRKKEANKATRANHNRRTMADRKRSKGMIPS
::::::::::::::::::::::::::::::::::::::::::
XP_011 GHGQSRETTQERRKKEANKATRANHNRRTMADRKRSKGMIPS
730 740 750 760
>>XP_011528746 (OMIM: 614216) PREDICTED: activating sign (762 aa)
initn: 4517 init1: 4517 opt: 5045 Z-score: 4576.1 bits: 857.4 E(85289): 0
Smith-Waterman score: 5045; 99.3% identity (99.3% similar) in 762 aa overlap (1-757:1-762)
10 20 30 40 50 60
pF1KE2 MPALPLDQLQITHKDPKTGKLRTSPALHPEQKADRYFVLYKPPPKDNIPALVEEYLERAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPALPLDQLQITHKDPKTGKLRTSPALHPEQKADRYFVLYKPPPKDNIPALVEEYLERAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 FVANDLDWLLALPHDKFWCQVIFDETLQKCLDSYLRYVPRKFDEGVASAPEVVDMQKRLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FVANDLDWLLALPHDKFWCQVIFDETLQKCLDSYLRYVPRKFDEGVASAPEVVDMQKRLH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 RSVFLTFLRMSTHKESKDHFISPSAFGEILYNNFLFDIPKILDLCVLFGKGNSPLLQKMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSVFLTFLRMSTHKESKDHFISPSAFGEILYNNFLFDIPKILDLCVLFGKGNSPLLQKMI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 GNIFTQQPSYYSDLDETLPTILQVFSNILQHCGLQGDGANTTPQKLEERGRLTPSDMPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNIFTQQPSYYSDLDETLPTILQVFSNILQHCGLQGDGANTTPQKLEERGRLTPSDMPLL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 ELKDIVLYLCDTCTTLWAFLDIFPLACQTFQKHDFCYRLASFYEAAIPEMESAIKKRRLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELKDIVLYLCDTCTTLWAFLDIFPLACQTFQKHDFCYRLASFYEAAIPEMESAIKKRRLE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 DSKLLGDLWQRLSHSRKKLMEIFHIILNQICLLPILESSCDNIQGFIEEFLQIFSSLLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSKLLGDLWQRLSHSRKKLMEIFHIILNQICLLPILESSCDNIQGFIEEFLQIFSSLLQE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 KRFLRDYDALFPVAEDISLLQQASSVLDETRTAYILQAVESAWEGVDRRKATDAKDPSVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRFLRDYDALFPVAEDISLLQQASSVLDETRTAYILQAVESAWEGVDRRKATDAKDPSVI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 EEPNGEPNGVTVTAEAVSQASSHPENSEEEECMGAAAAVGPAMCGVELDSLISQVKDLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEPNGEPNGVTVTAEAVSQASSHPENSEEEECMGAAAAVGPAMCGVELDSLISQVKDLLP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 DLGEGFILACLEYYHYDPEQVINNILEERLAPTLSQLDRNLDREMKPDPTPLLTSRHNVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLGEGFILACLEYYHYDPEQVINNILEERLAPTLSQLDRNLDREMKPDPTPLLTSRHNVF
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 QNDEFDVFSRDSVDLSRVHKGKSTRKEENTRSLLNDKRAVAAQRQRYEQYSVVVEEVPLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNDEFDVFSRDSVDLSRVHKGKSTRKEENTRSLLNDKRAVAAQRQRYEQYSVVVEEVPLQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 PGESLPYHSVYYEDEYDDTYDGNQVGANDADSDDELISRRPFTIPQVLRTKVPREGQEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGESLPYHSVYYEDEYDDTYDGNQVGANDADSDDELISRRPFTIPQVLRTKVPREGQEED
610 620 630 640 650 660
670 680 690 700 710
pF1KE2 DDDEEDDADEEAPK-----PDHFVQDPAVLREKAEARRMAFLAKKGYRHDSSTAVAGSPR
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_011 DDDEEDDADEEAPKVPPWQPDHFVQDPAVLREKAEARRMAFLAKKGYRHDSSTAVAGSPR
670 680 690 700 710 720
720 730 740 750
pF1KE2 GHGQSRETTQERRKKEANKATRANHNRRTMADRKRSKGMIPS
::::::::::::::::::::::::::::::::::::::::::
XP_011 GHGQSRETTQERRKKEANKATRANHNRRTMADRKRSKGMIPS
730 740 750 760
757 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 12:55:43 2016 done: Sun Nov 6 12:55:44 2016
Total Scan time: 12.380 Total Display time: 0.240
Function used was FASTA [36.3.4 Apr, 2011]