Result of FASTA (ccds) for
pFN21AE2074
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2074, 737 aa
1>>>pF1KE2074 737 - 737 aa - 737 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.3515+/-0.000908; mu= 11.0153+/- 0.055
mean_var=120.6350+/-24.186, 0's: 0 Z-trim(109.3): 7 B-trim: 0 in 0/51
Lambda= 0.116772
statistics sampled from 10790 (10793) to 10790 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.68), E-opt: 0.2 (0.332), width: 16
Scan time: 3.860
The best scores are: opt bits E(32554)
CCDS12747.1 GYS1 gene_id:2997|Hs108|chr19 ( 737) 5013 856.0 0
CCDS54292.1 GYS1 gene_id:2997|Hs108|chr19 ( 673) 3879 664.9 1.1e-190
CCDS8690.1 GYS2 gene_id:2998|Hs108|chr12 ( 703) 3543 608.3 1.3e-173
>>CCDS12747.1 GYS1 gene_id:2997|Hs108|chr19 (737 aa)
initn: 5013 init1: 5013 opt: 5013 Z-score: 4568.5 bits: 856.0 E(32554): 0
Smith-Waterman score: 5013; 100.0% identity (100.0% similar) in 737 aa overlap (1-737:1-737)
10 20 30 40 50 60
pF1KE2 MPLNRTLSMSSLPGLEDWEDEFDLENAVLFEVAWEVANKVGGIYTVLQTKAKVTGDEWGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 MPLNRTLSMSSLPGLEDWEDEFDLENAVLFEVAWEVANKVGGIYTVLQTKAKVTGDEWGD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 NYFLVGPYTEQGVRTQVELLEAPTPALKRTLDSMNSKGCKVYFGRWLIEGGPLVVLLDVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 NYFLVGPYTEQGVRTQVELLEAPTPALKRTLDSMNSKGCKVYFGRWLIEGGPLVVLLDVG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 ASAWALERWKGELWDTCNIGVPWYDREANDAVLFGFLTTWFLGEFLAQSEEKPHVVAHFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 ASAWALERWKGELWDTCNIGVPWYDREANDAVLFGFLTTWFLGEFLAQSEEKPHVVAHFH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 EWLAGVGLCLCRARRLPVATIFTTHATLLGRYLCAGAVDFYNNLENFNVDKEAGERQIYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 EWLAGVGLCLCRARRLPVATIFTTHATLLGRYLCAGAVDFYNNLENFNVDKEAGERQIYH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 RYCMERAAAHCAHVFTTVSQITAIEAQHLLKRKPDIVTPNGLNVKKFSAMHEFQNLHAQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 RYCMERAAAHCAHVFTTVSQITAIEAQHLLKRKPDIVTPNGLNVKKFSAMHEFQNLHAQS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 KARIQEFVRGHFYGHLDFNLDKTLYFFIAGRYEFSNKGADVFLEALARLNYLLRVNGSEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 KARIQEFVRGHFYGHLDFNLDKTLYFFIAGRYEFSNKGADVFLEALARLNYLLRVNGSEQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 TVVAFFIMPARTNNFNVETLKGQAVRKQLWDTANTVKEKFGRKLYESLLVGSLPDMNKML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 TVVAFFIMPARTNNFNVETLKGQAVRKQLWDTANTVKEKFGRKLYESLLVGSLPDMNKML
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 DKEDFTMMKRAIFATQRQSFPPVCTHNMLDDSSDPILTTIRRIGLFNSSADRVKVIFHPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 DKEDFTMMKRAIFATQRQSFPPVCTHNMLDDSSDPILTTIRRIGLFNSSADRVKVIFHPE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 FLSSTSPLLPVDYEEFVRGCHLGVFPSYYEPWGYTPAECTVMGIPSISTNLSGFGCFMEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 FLSSTSPLLPVDYEEFVRGCHLGVFPSYYEPWGYTPAECTVMGIPSISTNLSGFGCFMEE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 HIADPSAYGIYILDRRFRSLDDSCSQLTSFLYSFCQQSRRQRIIQRNRTERLSDLLDWKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 HIADPSAYGIYILDRRFRSLDDSCSQLTSFLYSFCQQSRRQRIIQRNRTERLSDLLDWKY
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 LGRYYMSARHMALSKAFPEHFTYEPNEADAAQGYRYPRPASVPPSPSLSRHSSPHQSEDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 LGRYYMSARHMALSKAFPEHFTYEPNEADAAQGYRYPRPASVPPSPSLSRHSSPHQSEDE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 EDPRNGPLEEDGERYDEDEEAAKDRRNIRAPEWPRRASCTSSTSGSKRNSVDTATSSSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 EDPRNGPLEEDGERYDEDEEAAKDRRNIRAPEWPRRASCTSSTSGSKRNSVDTATSSSLS
670 680 690 700 710 720
730
pF1KE2 TPSEPLSPTSSLGEERN
:::::::::::::::::
CCDS12 TPSEPLSPTSSLGEERN
730
>>CCDS54292.1 GYS1 gene_id:2997|Hs108|chr19 (673 aa)
initn: 3879 init1: 3879 opt: 3879 Z-score: 3536.7 bits: 664.9 E(32554): 1.1e-190
Smith-Waterman score: 4407; 91.3% identity (91.3% similar) in 737 aa overlap (1-737:1-673)
10 20 30 40 50 60
pF1KE2 MPLNRTLSMSSLPGLEDWEDEFDLENAVLFEVAWEVANKVGGIYTVLQTKAKVTGDEWGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MPLNRTLSMSSLPGLEDWEDEFDLENAVLFEVAWEVANKVGGIYTVLQTKAKVTGDEWGD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 NYFLVGPYTEQGVRTQVELLEAPTPALKRTLDSMNSKGCKVYFGRWLIEGGPLVVLLDVG
::::::::::::::::::::::::::::::::::::::::
CCDS54 NYFLVGPYTEQGVRTQVELLEAPTPALKRTLDSMNSKGCK--------------------
70 80 90 100
130 140 150 160 170 180
pF1KE2 ASAWALERWKGELWDTCNIGVPWYDREANDAVLFGFLTTWFLGEFLAQSEEKPHVVAHFH
::::::::::::::::
CCDS54 --------------------------------------------FLAQSEEKPHVVAHFH
110
190 200 210 220 230 240
pF1KE2 EWLAGVGLCLCRARRLPVATIFTTHATLLGRYLCAGAVDFYNNLENFNVDKEAGERQIYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EWLAGVGLCLCRARRLPVATIFTTHATLLGRYLCAGAVDFYNNLENFNVDKEAGERQIYH
120 130 140 150 160 170
250 260 270 280 290 300
pF1KE2 RYCMERAAAHCAHVFTTVSQITAIEAQHLLKRKPDIVTPNGLNVKKFSAMHEFQNLHAQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 RYCMERAAAHCAHVFTTVSQITAIEAQHLLKRKPDIVTPNGLNVKKFSAMHEFQNLHAQS
180 190 200 210 220 230
310 320 330 340 350 360
pF1KE2 KARIQEFVRGHFYGHLDFNLDKTLYFFIAGRYEFSNKGADVFLEALARLNYLLRVNGSEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 KARIQEFVRGHFYGHLDFNLDKTLYFFIAGRYEFSNKGADVFLEALARLNYLLRVNGSEQ
240 250 260 270 280 290
370 380 390 400 410 420
pF1KE2 TVVAFFIMPARTNNFNVETLKGQAVRKQLWDTANTVKEKFGRKLYESLLVGSLPDMNKML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TVVAFFIMPARTNNFNVETLKGQAVRKQLWDTANTVKEKFGRKLYESLLVGSLPDMNKML
300 310 320 330 340 350
430 440 450 460 470 480
pF1KE2 DKEDFTMMKRAIFATQRQSFPPVCTHNMLDDSSDPILTTIRRIGLFNSSADRVKVIFHPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 DKEDFTMMKRAIFATQRQSFPPVCTHNMLDDSSDPILTTIRRIGLFNSSADRVKVIFHPE
360 370 380 390 400 410
490 500 510 520 530 540
pF1KE2 FLSSTSPLLPVDYEEFVRGCHLGVFPSYYEPWGYTPAECTVMGIPSISTNLSGFGCFMEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 FLSSTSPLLPVDYEEFVRGCHLGVFPSYYEPWGYTPAECTVMGIPSISTNLSGFGCFMEE
420 430 440 450 460 470
550 560 570 580 590 600
pF1KE2 HIADPSAYGIYILDRRFRSLDDSCSQLTSFLYSFCQQSRRQRIIQRNRTERLSDLLDWKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 HIADPSAYGIYILDRRFRSLDDSCSQLTSFLYSFCQQSRRQRIIQRNRTERLSDLLDWKY
480 490 500 510 520 530
610 620 630 640 650 660
pF1KE2 LGRYYMSARHMALSKAFPEHFTYEPNEADAAQGYRYPRPASVPPSPSLSRHSSPHQSEDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LGRYYMSARHMALSKAFPEHFTYEPNEADAAQGYRYPRPASVPPSPSLSRHSSPHQSEDE
540 550 560 570 580 590
670 680 690 700 710 720
pF1KE2 EDPRNGPLEEDGERYDEDEEAAKDRRNIRAPEWPRRASCTSSTSGSKRNSVDTATSSSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EDPRNGPLEEDGERYDEDEEAAKDRRNIRAPEWPRRASCTSSTSGSKRNSVDTATSSSLS
600 610 620 630 640 650
730
pF1KE2 TPSEPLSPTSSLGEERN
:::::::::::::::::
CCDS54 TPSEPLSPTSSLGEERN
660 670
>>CCDS8690.1 GYS2 gene_id:2998|Hs108|chr12 (703 aa)
initn: 3534 init1: 2723 opt: 3543 Z-score: 3230.5 bits: 608.3 E(32554): 1.3e-173
Smith-Waterman score: 3543; 72.4% identity (91.7% similar) in 688 aa overlap (5-691:5-684)
10 20 30 40 50
pF1KE2 MPLNRTLSMSSLPGLEDWE-DEFDLENAVLFEVAWEVANKVGGIYTVLQTKAKVTGDEWG
:.::..:: :: .:: .:. .:. .::::::::.:::::::::.:::::.:.::::
CCDS86 MLRGRSLSVTSLGGLPQWEVEELPVEELLLFEVAWEVTNKVGGIYTVIQTKAKTTADEWG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 DNYFLVGPYTEQGVRTQVELLEAPTPALKRTLDSMNSKGCKVYFGRWLIEGGPLVVLLDV
.::::.::: :....:::: : . :..:..:.::..::.:.::::::::.: :::.:.
CCDS86 ENYFLIGPYFEHNMKTQVEQCEPVNDAVRRAVDAMNKHGCQVHFGRWLIEGSPYVVLFDI
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 GASAWALERWKGELWDTCNIGVPWYDREANDAVLFGFLTTWFLGEFLAQSEEKPHVVAHF
: ::: :.::::.::..:..:.:..:::::: ..:: ::.::: : ... : .:::.:
CCDS86 GYSAWNLDRWKGDLWEACSVGIPYHDREANDMLIFGSLTAWFLKEVTDHADGK-YVVAQF
130 140 150 160 170
180 190 200 210 220 230
pF1KE2 HEWLAGVGLCLCRARRLPVATIFTTHATLLGRYLCAGAVDFYNNLENFNVDKEAGERQIY
::: ::.:: : :::.::.:::::::::::::::::. .::::.:..::.::::::::::
CCDS86 HEWQAGIGLILSRARKLPIATIFTTHATLLGRYLCAANIDFYNHLDKFNIDKEAGERQIY
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE2 HRYCMERAAAHCAHVFTTVSQITAIEAQHLLKRKPDIVTPNGLNVKKFSAMHEFQNLHAQ
::::::::..::::::::::.::::::.:.::::::.:::::::::::::.::::::::.
CCDS86 HRYCMERASVHCAHVFTTVSEITAIEAEHMLKRKPDVVTPNGLNVKKFSAVHEFQNLHAM
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE2 SKARIQEFVRGHFYGHLDFNLDKTLYFFIAGRYEFSNKGADVFLEALARLNYLLRVNGSE
:::::.::::::::::::.:.:::..::::::::::::::.:::.:.:::.:::.. :.
CCDS86 YKARIQDFVRGHFYGHLDFDLEKTLFLFIAGRYEFSNKGADIFLESLSRLNFLLRMHKSD
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE2 QTVVAFFIMPARTNNFNVETLKGQAVRKQLWDTANTVKEKFGRKLYESLLVGSLPDMNKM
::..::::::.::::::::::::::::::::.:..::::::.:::..:: : .::.: .
CCDS86 ITVMVFFIMPAKTNNFNVETLKGQAVRKQLWDVAHSVKEKFGKKLYDALLRGEIPDLNDI
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE2 LDKEDFTMMKRAIFATQRQSFPPVCTHNMLDDSSDPILTTIRRIGLFNSSADRVKVIFHP
::..:.:.::::::.:::::.::: ::::.:::.::::.:::::::::. .::::::.::
CCDS86 LDRDDLTIMKRAIFSTQRQSLPPVTTHNMIDDSTDPILSTIRRIGLFNNRTDRVKVILHP
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE2 EFLSSTSPLLPVDYEEFVRGCHLGVFPSYYEPWGYTPAECTVMGIPSISTNLSGFGCFME
:::::::::::.:::::::::::::::::::::::::::::::::::..::::::::::.
CCDS86 EFLSSTSPLLPMDYEEFVRGCHLGVFPSYYEPWGYTPAECTVMGIPSVTTNLSGFGCFMQ
480 490 500 510 520 530
540 550 560 570 580 590
pF1KE2 EHIADPSAYGIYILDRRFRSLDDSCSQLTSFLYSFCQQSRRQRIIQRNRTERLSDLLDWK
::.:::.::::::.:::::: ::::.:::.:::.::.::::::::::::::::::::::.
CCDS86 EHVADPTAYGIYIVDRRFRSPDDSCNQLTKFLYGFCKQSRRQRIIQRNRTERLSDLLDWR
540 550 560 570 580 590
600 610 620 630 640 650
pF1KE2 YLGRYYMSARHMALSKAFPEHFTYEPNEADAAQGYRYPRPASVPPSPSLSRHSSPHQSED
::::::. :::..::.:::..: : . ...:..::::.::::::: :. ::: :: :
CCDS86 YLGRYYQHARHLTLSRAFPDKFHVELTSPPTTEGFKYPRPSSVPPSPSGSQASSP-QSSD
600 610 620 630 640 650
660 670 680 690 700 710
pF1KE2 EEDPRNGPLEEDGERYDEDEEAAKDRRNIRAPEWPRRASCTSSTSGSKRNSVDTATSSSL
:: : . :::::.::: .:: ::..:
CCDS86 VED------EVEDERYDEEEEAERDRLNIKSPFSLSHVPHGKKKLHGEYKN
660 670 680 690 700
720 730
pF1KE2 STPSEPLSPTSSLGEERN
737 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 13:17:14 2016 done: Sun Nov 6 13:17:15 2016
Total Scan time: 3.860 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]