Result of FASTA (omim) for
pFN21AE2071
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2071, 730 aa
1>>>pF1KE2071 730 - 730 aa - 730 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.4286+/-0.000391; mu= -3.9843+/- 0.024
mean_var=280.2164+/-57.971, 0's: 0 Z-trim(120.4): 35 B-trim: 0 in 0/57
Lambda= 0.076617
statistics sampled from 35663 (35706) to 35663 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.737), E-opt: 0.2 (0.419), width: 16
Scan time: 12.250
The best scores are: opt bits E(85289)
NP_057532 (OMIM: 610617) denticleless protein homo ( 730) 4971 563.4 1.1e-159
NP_001273159 (OMIM: 610617) denticleless protein h ( 688) 4561 518.1 4.7e-146
XP_011507916 (OMIM: 610617) PREDICTED: denticleles ( 668) 4521 513.7 9.8e-145
NP_001273158 (OMIM: 610617) denticleless protein h ( 459) 3110 357.6 6.5e-98
>>NP_057532 (OMIM: 610617) denticleless protein homolog (730 aa)
initn: 4971 init1: 4971 opt: 4971 Z-score: 2987.7 bits: 563.4 E(85289): 1.1e-159
Smith-Waterman score: 4971; 100.0% identity (100.0% similar) in 730 aa overlap (1-730:1-730)
10 20 30 40 50 60
pF1KE2 MLFNSVLRQPQLGVLRNGWSSQYPLQSLLTGYQCSGNDEHTSYGETGVPVPPFGCTFSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MLFNSVLRQPQLGVLRNGWSSQYPLQSLLTGYQCSGNDEHTSYGETGVPVPPFGCTFSSA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PNMEHVLAVANEEGFVRLYNTESQSFRKKCFKEWMAHWNAVFDLAWVPGELKLVTAAGDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 PNMEHVLAVANEEGFVRLYNTESQSFRKKCFKEWMAHWNAVFDLAWVPGELKLVTAAGDQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 TAKFWDVKAGELIGTCKGHQCSLKSVAFSKFEKAVFCTGGRDGNIMVWDTRCNKKDGFYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 TAKFWDVKAGELIGTCKGHQCSLKSVAFSKFEKAVFCTGGRDGNIMVWDTRCNKKDGFYR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 QVNQISGAHNTSDKQTPSKPKKKQNSKGLAPSVDFQQSVTVVLFQDENTLVSAGAVDGII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 QVNQISGAHNTSDKQTPSKPKKKQNSKGLAPSVDFQQSVTVVLFQDENTLVSAGAVDGII
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 KVWDLRKNYTAYRQEPIASKSFLYPGSSTRKLGYSSLILDSTGSTLFANCTDDNIYMFNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 KVWDLRKNYTAYRQEPIASKSFLYPGSSTRKLGYSSLILDSTGSTLFANCTDDNIYMFNM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 TGLKTSPVAIFNGHQNSTFYVKSSLSPDDQFLVSGSSDEAAYIWKVSTPWQPPTVLLGHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 TGLKTSPVAIFNGHQNSTFYVKSSLSPDDQFLVSGSSDEAAYIWKVSTPWQPPTVLLGHS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 QEVTSVCWCPSDFTKIATCSDDNTLKIWRLNRGLEEKPGGDKLSTVGWASQKKKESRPGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 QEVTSVCWCPSDFTKIATCSDDNTLKIWRLNRGLEEKPGGDKLSTVGWASQKKKESRPGL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 VTVTSSQSTPAKAPRVKCNPSNSSPSSAACAPSCAGDLPLPSNTPTFSIKTSPAKARSPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 VTVTSSQSTPAKAPRVKCNPSNSSPSSAACAPSCAGDLPLPSNTPTFSIKTSPAKARSPI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 NRRGSVSSVSPKPPSSFKMSIRNWVTRTPSSSPPITPPASETKIMSPRKALIPVSQKSSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 NRRGSVSSVSPKPPSSFKMSIRNWVTRTPSSSPPITPPASETKIMSPRKALIPVSQKSSQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 AEACSESRNRVKRRLDSSCLESVKQKCVKSCNCVTELDGQVENLHLDLCCLAGNQEDLSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 AEACSESRNRVKRRLDSSCLESVKQKCVKSCNCVTELDGQVENLHLDLCCLAGNQEDLSK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 DSLGPTKSSKIEGAGTSISEPPSPISPYASESCGTLPLPLRPCGEGSEMVGKENSSPENK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 DSLGPTKSSKIEGAGTSISEPPSPISPYASESCGTLPLPLRPCGEGSEMVGKENSSPENK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 NWLLAMAAKRKAENPSPRSPSSQTPNSRRQSGKTLPSPVTITPSSMRKICTYFHRKSQED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 NWLLAMAAKRKAENPSPRSPSSQTPNSRRQSGKTLPSPVTITPSSMRKICTYFHRKSQED
670 680 690 700 710 720
730
pF1KE2 FCGPEHSTEL
::::::::::
NP_057 FCGPEHSTEL
730
>>NP_001273159 (OMIM: 610617) denticleless protein homol (688 aa)
initn: 4555 init1: 4555 opt: 4561 Z-score: 2743.1 bits: 518.1 E(85289): 4.7e-146
Smith-Waterman score: 4570; 94.2% identity (94.2% similar) in 730 aa overlap (1-730:1-688)
10 20 30 40 50 60
pF1KE2 MLFNSVLRQPQLGVLRNGWSSQYPLQSLLTGYQCSGNDEHTSYGETGVPVPPFGCTFSSA
::::::::::::::::: :
NP_001 MLFNSVLRQPQLGVLRN------------------------------------------A
10
70 80 90 100 110 120
pF1KE2 PNMEHVLAVANEEGFVRLYNTESQSFRKKCFKEWMAHWNAVFDLAWVPGELKLVTAAGDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNMEHVLAVANEEGFVRLYNTESQSFRKKCFKEWMAHWNAVFDLAWVPGELKLVTAAGDQ
20 30 40 50 60 70
130 140 150 160 170 180
pF1KE2 TAKFWDVKAGELIGTCKGHQCSLKSVAFSKFEKAVFCTGGRDGNIMVWDTRCNKKDGFYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAKFWDVKAGELIGTCKGHQCSLKSVAFSKFEKAVFCTGGRDGNIMVWDTRCNKKDGFYR
80 90 100 110 120 130
190 200 210 220 230 240
pF1KE2 QVNQISGAHNTSDKQTPSKPKKKQNSKGLAPSVDFQQSVTVVLFQDENTLVSAGAVDGII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVNQISGAHNTSDKQTPSKPKKKQNSKGLAPSVDFQQSVTVVLFQDENTLVSAGAVDGII
140 150 160 170 180 190
250 260 270 280 290 300
pF1KE2 KVWDLRKNYTAYRQEPIASKSFLYPGSSTRKLGYSSLILDSTGSTLFANCTDDNIYMFNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVWDLRKNYTAYRQEPIASKSFLYPGSSTRKLGYSSLILDSTGSTLFANCTDDNIYMFNM
200 210 220 230 240 250
310 320 330 340 350 360
pF1KE2 TGLKTSPVAIFNGHQNSTFYVKSSLSPDDQFLVSGSSDEAAYIWKVSTPWQPPTVLLGHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGLKTSPVAIFNGHQNSTFYVKSSLSPDDQFLVSGSSDEAAYIWKVSTPWQPPTVLLGHS
260 270 280 290 300 310
370 380 390 400 410 420
pF1KE2 QEVTSVCWCPSDFTKIATCSDDNTLKIWRLNRGLEEKPGGDKLSTVGWASQKKKESRPGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEVTSVCWCPSDFTKIATCSDDNTLKIWRLNRGLEEKPGGDKLSTVGWASQKKKESRPGL
320 330 340 350 360 370
430 440 450 460 470 480
pF1KE2 VTVTSSQSTPAKAPRVKCNPSNSSPSSAACAPSCAGDLPLPSNTPTFSIKTSPAKARSPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTVTSSQSTPAKAPRVKCNPSNSSPSSAACAPSCAGDLPLPSNTPTFSIKTSPAKARSPI
380 390 400 410 420 430
490 500 510 520 530 540
pF1KE2 NRRGSVSSVSPKPPSSFKMSIRNWVTRTPSSSPPITPPASETKIMSPRKALIPVSQKSSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NRRGSVSSVSPKPPSSFKMSIRNWVTRTPSSSPPITPPASETKIMSPRKALIPVSQKSSQ
440 450 460 470 480 490
550 560 570 580 590 600
pF1KE2 AEACSESRNRVKRRLDSSCLESVKQKCVKSCNCVTELDGQVENLHLDLCCLAGNQEDLSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEACSESRNRVKRRLDSSCLESVKQKCVKSCNCVTELDGQVENLHLDLCCLAGNQEDLSK
500 510 520 530 540 550
610 620 630 640 650 660
pF1KE2 DSLGPTKSSKIEGAGTSISEPPSPISPYASESCGTLPLPLRPCGEGSEMVGKENSSPENK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSLGPTKSSKIEGAGTSISEPPSPISPYASESCGTLPLPLRPCGEGSEMVGKENSSPENK
560 570 580 590 600 610
670 680 690 700 710 720
pF1KE2 NWLLAMAAKRKAENPSPRSPSSQTPNSRRQSGKTLPSPVTITPSSMRKICTYFHRKSQED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NWLLAMAAKRKAENPSPRSPSSQTPNSRRQSGKTLPSPVTITPSSMRKICTYFHRKSQED
620 630 640 650 660 670
730
pF1KE2 FCGPEHSTEL
::::::::::
NP_001 FCGPEHSTEL
680
>>XP_011507916 (OMIM: 610617) PREDICTED: denticleless pr (668 aa)
initn: 4521 init1: 4521 opt: 4521 Z-score: 2719.4 bits: 513.7 E(85289): 9.8e-145
Smith-Waterman score: 4521; 99.7% identity (99.9% similar) in 668 aa overlap (63-730:1-668)
40 50 60 70 80 90
pF1KE2 QCSGNDEHTSYGETGVPVPPFGCTFSSAPNMEHVLAVANEEGFVRLYNTESQSFRKKCFK
::::::::::::::::::::::::::::::
XP_011 MEHVLAVANEEGFVRLYNTESQSFRKKCFK
10 20 30
100 110 120 130 140 150
pF1KE2 EWMAHWNAVFDLAWVPGELKLVTAAGDQTAKFWDVKAGELIGTCKGHQCSLKSVAFSKFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EWMAHWNAVFDLAWVPGELKLVTAAGDQTAKFWDVKAGELIGTCKGHQCSLKSVAFSKFE
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE2 KAVFCTGGRDGNIMVWDTRCNKKDGFYRQVNQISGAHNTSDKQTPSKPKKKQNSKGLAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAVFCTGGRDGNIMVWDTRCNKKDGFYRQVNQISGAHNTSDKQTPSKPKKKQNSKGLAPS
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE2 VDFQQSVTVVLFQDENTLVSAGAVDGIIKVWDLRKNYTAYRQEPIASKSFLYPGSSTRKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDFQQSVTVVLFQDENTLVSAGAVDGIIKVWDLRKNYTAYRQEPIASKSFLYPGSSTRKL
160 170 180 190 200 210
280 290 300 310 320 330
pF1KE2 GYSSLILDSTGSTLFANCTDDNIYMFNMTGLKTSPVAIFNGHQNSTFYVKSSLSPDDQFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GYSSLILDSTGSTLFANCTDDNIYMFNMTGLKTSPVAIFNGHQNSTFYVKSSLSPDDQFL
220 230 240 250 260 270
340 350 360 370 380 390
pF1KE2 VSGSSDEAAYIWKVSTPWQPPTVLLGHSQEVTSVCWCPSDFTKIATCSDDNTLKIWRLNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSGSSDEAAYIWKVSTPWQPPTVLLGHSQEVTSVCWCPSDFTKIATCSDDNTLKIWRLNR
280 290 300 310 320 330
400 410 420 430 440 450
pF1KE2 GLEEKPGGDKLSTVGWASQKKKESRPGLVTVTSSQSTPAKAPRVKCNPSNSSPSSAACAP
:::::::::::::::::::::::::::::::::::::::::::.::::::::::::::::
XP_011 GLEEKPGGDKLSTVGWASQKKKESRPGLVTVTSSQSTPAKAPRAKCNPSNSSPSSAACAP
340 350 360 370 380 390
460 470 480 490 500 510
pF1KE2 SCAGDLPLPSNTPTFSIKTSPAKARSPINRRGSVSSVSPKPPSSFKMSIRNWVTRTPSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SCAGDLPLPSNTPTFSIKTSPAKARSPINRRGSVSSVSPKPPSSFKMSIRNWVTRTPSSS
400 410 420 430 440 450
520 530 540 550 560 570
pF1KE2 PPITPPASETKIMSPRKALIPVSQKSSQAEACSESRNRVKRRLDSSCLESVKQKCVKSCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPITPPASETKIMSPRKALIPVSQKSSQAEACSESRNRVKRRLDSSCLESVKQKCVKSCN
460 470 480 490 500 510
580 590 600 610 620 630
pF1KE2 CVTELDGQVENLHLDLCCLAGNQEDLSKDSLGPTKSSKIEGAGTSISEPPSPISPYASES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CVTELDGQVENLHLDLCCLAGNQEDLSKDSLGPTKSSKIEGAGTSISEPPSPISPYASES
520 530 540 550 560 570
640 650 660 670 680 690
pF1KE2 CGTLPLPLRPCGEGSEMVGKENSSPENKNWLLAMAAKRKAENPSPRSPSSQTPNSRRQSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CGTLPLPLRPCGEGSEMVGKENSSPENKNWLLAMAAKRKAENPSPRSPSSQTPNSRRQSG
580 590 600 610 620 630
700 710 720 730
pF1KE2 KTLPSPVTITPSSMRKICTYFHRKSQEDFCGPEHSTEL
: ::::::::::::::::::::::::::::::::::::
XP_011 KKLPSPVTITPSSMRKICTYFHRKSQEDFCGPEHSTEL
640 650 660
>>NP_001273158 (OMIM: 610617) denticleless protein homol (459 aa)
initn: 3110 init1: 3110 opt: 3110 Z-score: 1878.8 bits: 357.6 E(85289): 6.5e-98
Smith-Waterman score: 3110; 99.8% identity (100.0% similar) in 459 aa overlap (272-730:1-459)
250 260 270 280 290 300
pF1KE2 VWDLRKNYTAYRQEPIASKSFLYPGSSTRKLGYSSLILDSTGSTLFANCTDDNIYMFNMT
.:::::::::::::::::::::::::::::
NP_001 MGYSSLILDSTGSTLFANCTDDNIYMFNMT
10 20 30
310 320 330 340 350 360
pF1KE2 GLKTSPVAIFNGHQNSTFYVKSSLSPDDQFLVSGSSDEAAYIWKVSTPWQPPTVLLGHSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLKTSPVAIFNGHQNSTFYVKSSLSPDDQFLVSGSSDEAAYIWKVSTPWQPPTVLLGHSQ
40 50 60 70 80 90
370 380 390 400 410 420
pF1KE2 EVTSVCWCPSDFTKIATCSDDNTLKIWRLNRGLEEKPGGDKLSTVGWASQKKKESRPGLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVTSVCWCPSDFTKIATCSDDNTLKIWRLNRGLEEKPGGDKLSTVGWASQKKKESRPGLV
100 110 120 130 140 150
430 440 450 460 470 480
pF1KE2 TVTSSQSTPAKAPRVKCNPSNSSPSSAACAPSCAGDLPLPSNTPTFSIKTSPAKARSPIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVTSSQSTPAKAPRVKCNPSNSSPSSAACAPSCAGDLPLPSNTPTFSIKTSPAKARSPIN
160 170 180 190 200 210
490 500 510 520 530 540
pF1KE2 RRGSVSSVSPKPPSSFKMSIRNWVTRTPSSSPPITPPASETKIMSPRKALIPVSQKSSQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRGSVSSVSPKPPSSFKMSIRNWVTRTPSSSPPITPPASETKIMSPRKALIPVSQKSSQA
220 230 240 250 260 270
550 560 570 580 590 600
pF1KE2 EACSESRNRVKRRLDSSCLESVKQKCVKSCNCVTELDGQVENLHLDLCCLAGNQEDLSKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EACSESRNRVKRRLDSSCLESVKQKCVKSCNCVTELDGQVENLHLDLCCLAGNQEDLSKD
280 290 300 310 320 330
610 620 630 640 650 660
pF1KE2 SLGPTKSSKIEGAGTSISEPPSPISPYASESCGTLPLPLRPCGEGSEMVGKENSSPENKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLGPTKSSKIEGAGTSISEPPSPISPYASESCGTLPLPLRPCGEGSEMVGKENSSPENKN
340 350 360 370 380 390
670 680 690 700 710 720
pF1KE2 WLLAMAAKRKAENPSPRSPSSQTPNSRRQSGKTLPSPVTITPSSMRKICTYFHRKSQEDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WLLAMAAKRKAENPSPRSPSSQTPNSRRQSGKTLPSPVTITPSSMRKICTYFHRKSQEDF
400 410 420 430 440 450
730
pF1KE2 CGPEHSTEL
:::::::::
NP_001 CGPEHSTEL
730 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 20:31:36 2016 done: Sun Nov 6 20:31:37 2016
Total Scan time: 12.250 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]