Result of FASTA (omim) for
pFN21AE2050
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2050, 671 aa
1>>>pF1KE2050 671 - 671 aa - 671 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.6870+/-0.000363; mu= 4.3958+/- 0.023
mean_var=167.2606+/-33.517, 0's: 0 Z-trim(118.5): 4 B-trim: 0 in 0/58
Lambda= 0.099169
statistics sampled from 31492 (31495) to 31492 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.707), E-opt: 0.2 (0.369), width: 16
Scan time: 12.530
The best scores are: opt bits E(85289)
NP_008878 (OMIM: 602122,614675) signal recognition ( 671) 4351 634.8 3e-181
XP_005265822 (OMIM: 602122,614675) PREDICTED: sign ( 663) 3511 514.7 4.5e-145
NP_001254651 (OMIM: 602122,614675) signal recognit ( 610) 2578 381.2 6.4e-105
>>NP_008878 (OMIM: 602122,614675) signal recognition par (671 aa)
initn: 4351 init1: 4351 opt: 4351 Z-score: 3374.9 bits: 634.8 E(85289): 3e-181
Smith-Waterman score: 4351; 100.0% identity (100.0% similar) in 671 aa overlap (1-671:1-671)
10 20 30 40 50 60
pF1KE2 MASGGSGGVSVPALWSEVNRYGQNGDFTRALKTVNKILQINKDDVTALHCKVVCLIQNGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 MASGGSGGVSVPALWSEVNRYGQNGDFTRALKTVNKILQINKDDVTALHCKVVCLIQNGS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 FKEALNVINTHTKVLANNSLSFEKAYCEYRLNRIENALKTIESANQQTDKLKELYGQVLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 FKEALNVINTHTKVLANNSLSFEKAYCEYRLNRIENALKTIESANQQTDKLKELYGQVLY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 RLERYDECLAVYRDLVRNSQDDYDEERKTNLSAVVAAQSNWEKVVPENLGLQEGTHELCY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 RLERYDECLAVYRDLVRNSQDDYDEERKTNLSAVVAAQSNWEKVVPENLGLQEGTHELCY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 NTACALIGQGQLNQAMKILQKAEDLCRRSLSEDTDGTEEDPQAELAIIHGQMAYILQLQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 NTACALIGQGQLNQAMKILQKAEDLCRRSLSEDTDGTEEDPQAELAIIHGQMAYILQLQG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 RTEEALQLYNQIIKLKPTDVGLLAVIANNIITINKDQNVFDSKKKVKLTNAEGVEFKLSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 RTEEALQLYNQIIKLKPTDVGLLAVIANNIITINKDQNVFDSKKKVKLTNAEGVEFKLSK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 KQLQAIEFNKALLAMYTNQAEQCRKISASLQSQSPEHLLPVLIQAAQLCREKQHTKAIEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 KQLQAIEFNKALLAMYTNQAEQCRKISASLQSQSPEHLLPVLIQAAQLCREKQHTKAIEL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 LQEFSDQHPENAAEIKLTMAQLKISQGNISKACLILRSIEELKHKPGMVSALVTMYSHEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 LQEFSDQHPENAAEIKLTMAQLKISQGNISKACLILRSIEELKHKPGMVSALVTMYSHEE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 DIDSAIEVFTQAIQWYQNHQPKSPAHLSLIREAANFKLKYGRKKEAISDLQQLWKQNPKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 DIDSAIEVFTQAIQWYQNHQPKSPAHLSLIREAANFKLKYGRKKEAISDLQQLWKQNPKD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 IHTLAQLISAYSLVDPEKAKALSKHLPSSDSMSLKVDVEALENSAGATYIRKKGGKVTGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 IHTLAQLISAYSLVDPEKAKALSKHLPSSDSMSLKVDVEALENSAGATYIRKKGGKVTGD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 SQPKEQGQGDLKKKKKKKKGKLPKNYDPKVTPDPERWLPMRERSYYRGRKKGKKKDQIGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 SQPKEQGQGDLKKKKKKKKGKLPKNYDPKVTPDPERWLPMRERSYYRGRKKGKKKDQIGK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 GTQGATAGASSELDASKTVSSPPTSPRPGSAATVSASTSNIIPPRHQKPAGAPATKKKQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 GTQGATAGASSELDASKTVSSPPTSPRPGSAATVSASTSNIIPPRHQKPAGAPATKKKQQ
610 620 630 640 650 660
670
pF1KE2 QKKKKGGKGGW
:::::::::::
NP_008 QKKKKGGKGGW
670
>>XP_005265822 (OMIM: 602122,614675) PREDICTED: signal r (663 aa)
initn: 3511 init1: 3511 opt: 3511 Z-score: 2725.5 bits: 514.7 E(85289): 4.5e-145
Smith-Waterman score: 3511; 100.0% identity (100.0% similar) in 547 aa overlap (1-547:116-662)
10 20 30
pF1KE2 MASGGSGGVSVPALWSEVNRYGQNGDFTRA
::::::::::::::::::::::::::::::
XP_005 AIIDFLLLLAASEILFRGRGLPAPPLVSSKMASGGSGGVSVPALWSEVNRYGQNGDFTRA
90 100 110 120 130 140
40 50 60 70 80 90
pF1KE2 LKTVNKILQINKDDVTALHCKVVCLIQNGSFKEALNVINTHTKVLANNSLSFEKAYCEYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKTVNKILQINKDDVTALHCKVVCLIQNGSFKEALNVINTHTKVLANNSLSFEKAYCEYR
150 160 170 180 190 200
100 110 120 130 140 150
pF1KE2 LNRIENALKTIESANQQTDKLKELYGQVLYRLERYDECLAVYRDLVRNSQDDYDEERKTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LNRIENALKTIESANQQTDKLKELYGQVLYRLERYDECLAVYRDLVRNSQDDYDEERKTN
210 220 230 240 250 260
160 170 180 190 200 210
pF1KE2 LSAVVAAQSNWEKVVPENLGLQEGTHELCYNTACALIGQGQLNQAMKILQKAEDLCRRSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSAVVAAQSNWEKVVPENLGLQEGTHELCYNTACALIGQGQLNQAMKILQKAEDLCRRSL
270 280 290 300 310 320
220 230 240 250 260 270
pF1KE2 SEDTDGTEEDPQAELAIIHGQMAYILQLQGRTEEALQLYNQIIKLKPTDVGLLAVIANNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SEDTDGTEEDPQAELAIIHGQMAYILQLQGRTEEALQLYNQIIKLKPTDVGLLAVIANNI
330 340 350 360 370 380
280 290 300 310 320 330
pF1KE2 ITINKDQNVFDSKKKVKLTNAEGVEFKLSKKQLQAIEFNKALLAMYTNQAEQCRKISASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ITINKDQNVFDSKKKVKLTNAEGVEFKLSKKQLQAIEFNKALLAMYTNQAEQCRKISASL
390 400 410 420 430 440
340 350 360 370 380 390
pF1KE2 QSQSPEHLLPVLIQAAQLCREKQHTKAIELLQEFSDQHPENAAEIKLTMAQLKISQGNIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSQSPEHLLPVLIQAAQLCREKQHTKAIELLQEFSDQHPENAAEIKLTMAQLKISQGNIS
450 460 470 480 490 500
400 410 420 430 440 450
pF1KE2 KACLILRSIEELKHKPGMVSALVTMYSHEEDIDSAIEVFTQAIQWYQNHQPKSPAHLSLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KACLILRSIEELKHKPGMVSALVTMYSHEEDIDSAIEVFTQAIQWYQNHQPKSPAHLSLI
510 520 530 540 550 560
460 470 480 490 500 510
pF1KE2 REAANFKLKYGRKKEAISDLQQLWKQNPKDIHTLAQLISAYSLVDPEKAKALSKHLPSSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 REAANFKLKYGRKKEAISDLQQLWKQNPKDIHTLAQLISAYSLVDPEKAKALSKHLPSSD
570 580 590 600 610 620
520 530 540 550 560 570
pF1KE2 SMSLKVDVEALENSAGATYIRKKGGKVTGDSQPKEQGQGDLKKKKKKKKGKLPKNYDPKV
:::::::::::::::::::::::::::::::::::::
XP_005 SMSLKVDVEALENSAGATYIRKKGGKVTGDSQPKEQGA
630 640 650 660
580 590 600 610 620 630
pF1KE2 TPDPERWLPMRERSYYRGRKKGKKKDQIGKGTQGATAGASSELDASKTVSSPPTSPRPGS
>>NP_001254651 (OMIM: 602122,614675) signal recognition (610 aa)
initn: 2578 init1: 2578 opt: 2578 Z-score: 2004.7 bits: 381.2 E(85289): 6.4e-105
Smith-Waterman score: 3840; 90.9% identity (90.9% similar) in 671 aa overlap (1-671:1-610)
10 20 30 40 50 60
pF1KE2 MASGGSGGVSVPALWSEVNRYGQNGDFTRALKTVNKILQINKDDVTALHCKVVCLIQNGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MASGGSGGVSVPALWSEVNRYGQNGDFTRALKTVNKILQINKDDVTALHCKVVCLIQNGS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 FKEALNVINTHTKVLANNSLSFEKAYCEYRLNRIENALKTIESANQQTDKLKELYGQVLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FKEALNVINTHTKVLANNSLSFEKAYCEYRLNRIENALKTIESANQQTDKLKELYGQVLY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 RLERYDECLAVYRDLVRNSQDDYDEERKTNLSAVVAAQSNWEKVVPENLGLQEGTHELCY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLERYDECLAVYRDLVRNSQDDYDEERKTNLSAVVAAQSNWEKVVPENLGLQEGTHELCY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 NTACALIGQGQLNQAMKILQKAEDLCRRSLSEDTDGTEEDPQAELAIIHGQMAYILQLQG
:::::::::::::::::::::::::::::::::::
NP_001 NTACALIGQGQLNQAMKILQKAEDLCRRSLSEDTD-------------------------
190 200 210
250 260 270 280 290 300
pF1KE2 RTEEALQLYNQIIKLKPTDVGLLAVIANNIITINKDQNVFDSKKKVKLTNAEGVEFKLSK
::::::::::::::::::::::::
NP_001 ------------------------------------QNVFDSKKKVKLTNAEGVEFKLSK
220 230
310 320 330 340 350 360
pF1KE2 KQLQAIEFNKALLAMYTNQAEQCRKISASLQSQSPEHLLPVLIQAAQLCREKQHTKAIEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQLQAIEFNKALLAMYTNQAEQCRKISASLQSQSPEHLLPVLIQAAQLCREKQHTKAIEL
240 250 260 270 280 290
370 380 390 400 410 420
pF1KE2 LQEFSDQHPENAAEIKLTMAQLKISQGNISKACLILRSIEELKHKPGMVSALVTMYSHEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQEFSDQHPENAAEIKLTMAQLKISQGNISKACLILRSIEELKHKPGMVSALVTMYSHEE
300 310 320 330 340 350
430 440 450 460 470 480
pF1KE2 DIDSAIEVFTQAIQWYQNHQPKSPAHLSLIREAANFKLKYGRKKEAISDLQQLWKQNPKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DIDSAIEVFTQAIQWYQNHQPKSPAHLSLIREAANFKLKYGRKKEAISDLQQLWKQNPKD
360 370 380 390 400 410
490 500 510 520 530 540
pF1KE2 IHTLAQLISAYSLVDPEKAKALSKHLPSSDSMSLKVDVEALENSAGATYIRKKGGKVTGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IHTLAQLISAYSLVDPEKAKALSKHLPSSDSMSLKVDVEALENSAGATYIRKKGGKVTGD
420 430 440 450 460 470
550 560 570 580 590 600
pF1KE2 SQPKEQGQGDLKKKKKKKKGKLPKNYDPKVTPDPERWLPMRERSYYRGRKKGKKKDQIGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQPKEQGQGDLKKKKKKKKGKLPKNYDPKVTPDPERWLPMRERSYYRGRKKGKKKDQIGK
480 490 500 510 520 530
610 620 630 640 650 660
pF1KE2 GTQGATAGASSELDASKTVSSPPTSPRPGSAATVSASTSNIIPPRHQKPAGAPATKKKQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTQGATAGASSELDASKTVSSPPTSPRPGSAATVSASTSNIIPPRHQKPAGAPATKKKQQ
540 550 560 570 580 590
670
pF1KE2 QKKKKGGKGGW
:::::::::::
NP_001 QKKKKGGKGGW
600 610
671 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 17:30:05 2016 done: Sun Nov 6 17:30:07 2016
Total Scan time: 12.530 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]