Result of FASTA (omim) for
pFN21AE2048
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2048, 669 aa
1>>>pF1KE2048 669 - 669 aa - 669 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.0537+/-0.000587; mu= -3.7692+/- 0.037
mean_var=528.9409+/-113.349, 0's: 0 Z-trim(118.4): 114 B-trim: 0 in 0/55
Lambda= 0.055766
statistics sampled from 31243 (31357) to 31243 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.674), E-opt: 0.2 (0.368), width: 16
Scan time: 12.970
The best scores are: opt bits E(85289)
NP_006319 (OMIM: 612409) RNA-binding protein 14 is ( 669) 4342 364.9 5.5e-100
NP_001185765 (OMIM: 612409) RNA-binding protein 14 ( 156) 979 93.5 6.3e-19
NP_001185766 (OMIM: 612409) RNA-binding protein 14 ( 119) 743 74.4 2.7e-13
NP_002887 (OMIM: 602571) RNA-binding protein 4 iso ( 364) 471 53.1 2.1e-06
NP_001185773 (OMIM: 602571) RNA-binding protein 4 ( 173) 401 47.1 6.6e-05
NP_001185772 (OMIM: 602571) RNA-binding protein 4 ( 143) 395 46.5 8.3e-05
>>NP_006319 (OMIM: 612409) RNA-binding protein 14 isofor (669 aa)
initn: 4342 init1: 4342 opt: 4342 Z-score: 1916.1 bits: 364.9 E(85289): 5.5e-100
Smith-Waterman score: 4342; 100.0% identity (100.0% similar) in 669 aa overlap (1-669:1-669)
10 20 30 40 50 60
pF1KE2 MKIFVGNVDGADTTPEELAALFAPYGTVMSCAVMKQFAFVHMRENAGALRAIEALHGHEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MKIFVGNVDGADTTPEELAALFAPYGTVMSCAVMKQFAFVHMRENAGALRAIEALHGHEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 RPGRALVVEMSRPRPLNTWKIFVGNVSAACTSQELRSLFERRGRVIECDVVKDYAFVHME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RPGRALVVEMSRPRPLNTWKIFVGNVSAACTSQELRSLFERRGRVIECDVVKDYAFVHME
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 KEADAKAAIAQLNGKEVKGKRINVELSTKGQKKGPGLAVQSGDKTKKPGAGDTAFPGTGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KEADAKAAIAQLNGKEVKGKRINVELSTKGQKKGPGLAVQSGDKTKKPGAGDTAFPGTGG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 FSATFDYQQAFGNSTGGFDGQARQPTPPFFGRDRSPLRRSPPRASYVAPLTAQPATYRAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 FSATFDYQQAFGNSTGGFDGQARQPTPPFFGRDRSPLRRSPPRASYVAPLTAQPATYRAQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 PSVSLGAAYRAQPSASLGVGYRTQPMTAQAASYRAQPSVSLGAPYRGQLASPSSQSAAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PSVSLGAAYRAQPSASLGVGYRTQPMTAQAASYRAQPSVSLGAPYRGQLASPSSQSAAAS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 SLGPYGGAQPSASALSSYGGQAAAASSLNSYGAQGSSLASYGNQPSSYGAQAASSYGVRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SLGPYGGAQPSASALSSYGGQAAAASSLNSYGAQGSSLASYGNQPSSYGAQAASSYGVRA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 AASSYNTQGAASSLGSYGAQAASYGAQSAASSLAYGAQAASYNAQPSASYNAQSAPYAAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AASSYNTQGAASSLGSYGAQAASYGAQSAASSLAYGAQAASYNAQPSASYNAQSAPYAAQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 QAASYSSQPAAYVAQPATAAAYASQPAAYAAQATTPMAGSYGAQPVVQTQLNSYGAQASM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QAASYSSQPAAYVAQPATAAAYASQPAAYAAQATTPMAGSYGAQPVVQTQLNSYGAQASM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 GLSGSYGAQSAAAATGSYGAAAAYGAQPSATLAAPYRTQSSASLAASYAAQQHPQAAASY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GLSGSYGAQSAAAATGSYGAAAAYGAQPSATLAAPYRTQSSASLAASYAAQQHPQAAASY
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 RGQPGNAYDGAGQPSAAYLSMSQGAVANANSTPPPYERTRLSPPRASYDDPYKKAVAMSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RGQPGNAYDGAGQPSAAYLSMSQGAVANANSTPPPYERTRLSPPRASYDDPYKKAVAMSK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 RYGSDRRLAELSDYRRLSESQLSFRRSPTKSSLDYRRLPDAHSDYARYSGSYNDYLRAAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RYGSDRRLAELSDYRRLSESQLSFRRSPTKSSLDYRRLPDAHSDYARYSGSYNDYLRAAQ
610 620 630 640 650 660
pF1KE2 MHSGYQRRM
:::::::::
NP_006 MHSGYQRRM
>>NP_001185765 (OMIM: 612409) RNA-binding protein 14 iso (156 aa)
initn: 979 init1: 979 opt: 979 Z-score: 460.8 bits: 93.5 E(85289): 6.3e-19
Smith-Waterman score: 979; 100.0% identity (100.0% similar) in 150 aa overlap (1-150:1-150)
10 20 30 40 50 60
pF1KE2 MKIFVGNVDGADTTPEELAALFAPYGTVMSCAVMKQFAFVHMRENAGALRAIEALHGHEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKIFVGNVDGADTTPEELAALFAPYGTVMSCAVMKQFAFVHMRENAGALRAIEALHGHEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 RPGRALVVEMSRPRPLNTWKIFVGNVSAACTSQELRSLFERRGRVIECDVVKDYAFVHME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPGRALVVEMSRPRPLNTWKIFVGNVSAACTSQELRSLFERRGRVIECDVVKDYAFVHME
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 KEADAKAAIAQLNGKEVKGKRINVELSTKGQKKGPGLAVQSGDKTKKPGAGDTAFPGTGG
::::::::::::::::::::::::::::::
NP_001 KEADAKAAIAQLNGKEVKGKRINVELSTKGMVPTGV
130 140 150
>>NP_001185766 (OMIM: 612409) RNA-binding protein 14 iso (119 aa)
initn: 743 init1: 743 opt: 743 Z-score: 359.5 bits: 74.4 E(85289): 2.7e-13
Smith-Waterman score: 743; 100.0% identity (100.0% similar) in 112 aa overlap (1-112:1-112)
10 20 30 40 50 60
pF1KE2 MKIFVGNVDGADTTPEELAALFAPYGTVMSCAVMKQFAFVHMRENAGALRAIEALHGHEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKIFVGNVDGADTTPEELAALFAPYGTVMSCAVMKQFAFVHMRENAGALRAIEALHGHEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 RPGRALVVEMSRPRPLNTWKIFVGNVSAACTSQELRSLFERRGRVIECDVVKDYAFVHME
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPGRALVVEMSRPRPLNTWKIFVGNVSAACTSQELRSLFERRGRVIECDVVKGMVPTGV
70 80 90 100 110
130 140 150 160 170 180
pF1KE2 KEADAKAAIAQLNGKEVKGKRINVELSTKGQKKGPGLAVQSGDKTKKPGAGDTAFPGTGG
>>NP_002887 (OMIM: 602571) RNA-binding protein 4 isoform (364 aa)
initn: 505 init1: 322 opt: 471 Z-score: 235.9 bits: 53.1 E(85289): 2.1e-06
Smith-Waterman score: 487; 34.3% identity (59.8% similar) in 321 aa overlap (1-319:2-305)
10 20 30 40 50
pF1KE2 MKIFVGNVDGADTTPEELAALFAPYGTVMSCAVMKQFAFVHMRENAGALRAIEALHGHE
.:.:.::. ..: .:. .:: :: :. : ..:...:::......: ::. :: ..
NP_002 MVKLFIGNLP-REATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYK
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 LRPGRALVVEMSRPRPLNTWKIFVGNVSAACTSQELRSLFERRGRVIECDVVKDYAFVHM
:. : . :: :. . .. :. :::.: .::..:::. ::. : :::::.:::::::::
NP_002 LH-GVNINVEASKNKSKTSTKLHVGNISPTCTNKELRAKFEEYGPVIECDIVKDYAFVHM
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 EKEADAKAAIAQLNGKEVKGKRINVELSTKGQKKGPGLAVQSG-DKTKKPGAGDTAFP-G
:. :: :: :.. : .:::..:.:::. . .::.. ::: . : : . :
NP_002 ERAEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQSGCYRCGKEGHWSKECPID
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE2 TGGFSATFDYQQAFGNSTGGFDGQARQPTPPFFGRDRSPLRRSPPRASYVAPLTAQPATY
.: : : . .... :. .: : .: . : . .: : : :
NP_002 RSGRVA--DLTEQYNEQYGA----VRTPYTMSYG---DSLYYN---NAYGA-LDAYYKRC
180 190 200 210 220
240 250 260 270 280 290
pF1KE2 RAQPSVSLGAAYRAQPSASLGVGYRTQPMTAQAASYRAQPSVSLGAPYRGQLASPSSQSA
:: : :: :. :.. ..: :.:: :: .: :.: .:
NP_002 RAARSYEAVAAAAASVYNYAEQTLSQLPQVQNTAMASHLTSTSLD-PYDRHLL-PTSGAA
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE2 AASSLGPYGGAQPSASALSSYGGQAAAASSLNSYGAQGSSLASYGNQPSSYGAQAASSYG
:... . ..: .:.. : ::
NP_002 ATAAAAAAAAAAVTAASTSYYGRDRSPLRRATAPVPTVGEGYGYGHESELSQASAAARNS
290 300 310 320 330 340
>>NP_001185773 (OMIM: 602571) RNA-binding protein 4 isof (173 aa)
initn: 359 init1: 256 opt: 401 Z-score: 209.0 bits: 47.1 E(85289): 6.6e-05
Smith-Waterman score: 401; 44.3% identity (74.3% similar) in 140 aa overlap (1-140:2-139)
10 20 30 40 50
pF1KE2 MKIFVGNVDGADTTPEELAALFAPYGTVMSCAVMKQFAFVHMRENAGALRAIEALHGHE
.:.:.::. ..: .:. .:: :: :. : ..:...:::......: ::. :: ..
NP_001 MVKLFIGNLP-REATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYK
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 LRPGRALVVEMSRPRPLNTWKIFVGNVSAACTSQELRSLFERRGRVIECDVVKDYAFVHM
:. : . :: :. . .. :. :::.: .::..:::. ::. : :::::.:::::::::
NP_001 LH-GVNINVEASKNKSKTSTKLHVGNISPTCTNKELRAKFEEYGPVIECDIVKDYAFVHM
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 EKEADAKAAIAQLNGKEVKGKRINVELSTKGQKKGPGLAVQSGDKTKKPGAGDTAFPGTG
:. :: :: :.. : .::
NP_001 ERAEDAVEAIRGLDNTEFQGKITPVTEGYCCCNKGHTYIFKNCNLILESRKSRRC
120 130 140 150 160 170
>>NP_001185772 (OMIM: 602571) RNA-binding protein 4 isof (143 aa)
initn: 353 init1: 250 opt: 395 Z-score: 207.3 bits: 46.5 E(85289): 8.3e-05
Smith-Waterman score: 395; 43.9% identity (74.1% similar) in 139 aa overlap (1-139:2-138)
10 20 30 40 50
pF1KE2 MKIFVGNVDGADTTPEELAALFAPYGTVMSCAVMKQFAFVHMRENAGALRAIEALHGHE
.:.:.::. ..: .:. .:: :: :. : ..:...:::......: ::. :: ..
NP_001 MVKLFIGNLP-REATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYK
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 LRPGRALVVEMSRPRPLNTWKIFVGNVSAACTSQELRSLFERRGRVIECDVVKDYAFVHM
:. : . :: :. . .. :. :::.: .::..:::. ::. : :::::.:::::::::
NP_001 LH-GVNINVEASKNKSKTSTKLHVGNISPTCTNKELRAKFEEYGPVIECDIVKDYAFVHM
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 EKEADAKAAIAQLNGKEVKGKRINVELSTKGQKKGPGLAVQSGDKTKKPGAGDTAFPGTG
:. :: :: :.. : .:
NP_001 ERAEDAVEAIRGLDNTEFQGGMCVG
120 130 140
669 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 20:32:17 2016 done: Sun Nov 6 20:32:19 2016
Total Scan time: 12.970 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]