Result of FASTA (omim) for
pFN21AE2040
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2040, 651 aa
1>>>pF1KE2040 651 - 651 aa - 651 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.6099+/-0.000372; mu= 9.3566+/- 0.023
mean_var=133.6106+/-27.837, 0's: 0 Z-trim(117.9): 69 B-trim: 735 in 1/53
Lambda= 0.110957
statistics sampled from 30201 (30270) to 30201 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.702), E-opt: 0.2 (0.355), width: 16
Scan time: 10.620
The best scores are: opt bits E(85289)
NP_057250 (OMIM: 603566) E3 SUMO-protein ligase PI ( 651) 4330 704.8 2.5e-202
NP_001307616 (OMIM: 603566) E3 SUMO-protein ligase ( 653) 4291 698.5 1.9e-200
XP_016878177 (OMIM: 603566) PREDICTED: E3 SUMO-pro ( 653) 4291 698.5 1.9e-200
XP_011520429 (OMIM: 603566) PREDICTED: E3 SUMO-pro ( 645) 4287 697.9 3e-200
XP_016878178 (OMIM: 603566) PREDICTED: E3 SUMO-pro ( 644) 4283 697.2 4.6e-200
XP_011520428 (OMIM: 603566) PREDICTED: E3 SUMO-pro ( 660) 4283 697.2 4.7e-200
XP_016878180 (OMIM: 603566) PREDICTED: E3 SUMO-pro ( 642) 4276 696.1 1e-199
XP_016878179 (OMIM: 603566) PREDICTED: E3 SUMO-pro ( 642) 4276 696.1 1e-199
NP_006090 (OMIM: 605987) E3 SUMO-protein ligase PI ( 628) 2303 380.3 1.2e-104
XP_011524561 (OMIM: 603567) PREDICTED: E3 SUMO-pro ( 613) 1853 308.2 5.5e-83
NP_001310976 (OMIM: 603567) E3 SUMO-protein ligase ( 613) 1853 308.2 5.5e-83
XP_016881557 (OMIM: 603567) PREDICTED: E3 SUMO-pro ( 613) 1853 308.2 5.5e-83
XP_011524560 (OMIM: 603567) PREDICTED: E3 SUMO-pro ( 620) 1853 308.2 5.6e-83
XP_005258436 (OMIM: 603567) PREDICTED: E3 SUMO-pro ( 622) 1853 308.2 5.6e-83
XP_005258434 (OMIM: 603567) PREDICTED: E3 SUMO-pro ( 626) 1853 308.2 5.6e-83
XP_006722634 (OMIM: 603567) PREDICTED: E3 SUMO-pro ( 661) 1853 308.3 5.9e-83
XP_016881559 (OMIM: 603567) PREDICTED: E3 SUMO-pro ( 612) 1842 306.5 1.9e-82
NP_001310977 (OMIM: 603567) E3 SUMO-protein ligase ( 612) 1842 306.5 1.9e-82
NP_001310978 (OMIM: 603567) E3 SUMO-protein ligase ( 612) 1842 306.5 1.9e-82
XP_016881558 (OMIM: 603567) PREDICTED: E3 SUMO-pro ( 612) 1842 306.5 1.9e-82
NP_004662 (OMIM: 603567) E3 SUMO-protein ligase PI ( 621) 1842 306.5 1.9e-82
XP_006722635 (OMIM: 603567) PREDICTED: E3 SUMO-pro ( 660) 1842 306.5 2e-82
NP_001310975 (OMIM: 603567) E3 SUMO-protein ligase ( 571) 1836 305.5 3.4e-82
NP_001310983 (OMIM: 603567) E3 SUMO-protein ligase ( 563) 1802 300.1 1.5e-80
NP_001310980 (OMIM: 603567) E3 SUMO-protein ligase ( 563) 1802 300.1 1.5e-80
NP_001310982 (OMIM: 603567) E3 SUMO-protein ligase ( 563) 1802 300.1 1.5e-80
XP_016881561 (OMIM: 603567) PREDICTED: E3 SUMO-pro ( 563) 1802 300.1 1.5e-80
XP_016881560 (OMIM: 603567) PREDICTED: E3 SUMO-pro ( 563) 1802 300.1 1.5e-80
NP_001310981 (OMIM: 603567) E3 SUMO-protein ligase ( 563) 1802 300.1 1.5e-80
NP_775298 (OMIM: 603567) E3 SUMO-protein ligase PI ( 572) 1802 300.1 1.5e-80
XP_006722636 (OMIM: 603567) PREDICTED: E3 SUMO-pro ( 611) 1802 300.1 1.6e-80
NP_001310988 (OMIM: 603567) E3 SUMO-protein ligase ( 498) 1717 286.4 1.7e-76
NP_001310986 (OMIM: 603567) E3 SUMO-protein ligase ( 498) 1717 286.4 1.7e-76
NP_001310984 (OMIM: 603567) E3 SUMO-protein ligase ( 498) 1717 286.4 1.7e-76
NP_001310987 (OMIM: 603567) E3 SUMO-protein ligase ( 507) 1717 286.4 1.7e-76
NP_001310989 (OMIM: 603567) E3 SUMO-protein ligase ( 405) 1413 237.7 6.2e-62
NP_056981 (OMIM: 605989) E3 SUMO-protein ligase PI ( 510) 1217 206.4 2.1e-52
XP_011526362 (OMIM: 605989) PREDICTED: E3 SUMO-pro ( 529) 1217 206.4 2.2e-52
XP_016882357 (OMIM: 605989) PREDICTED: E3 SUMO-pro ( 319) 1012 173.5 1.1e-42
XP_005249927 (OMIM: 611196) PREDICTED: zinc finger ( 903) 323 63.4 4.1e-09
NP_001287888 (OMIM: 611196) zinc finger MIZ domain ( 862) 307 60.8 2.3e-08
XP_005249929 (OMIM: 611196) PREDICTED: zinc finger ( 894) 307 60.8 2.4e-08
NP_777589 (OMIM: 611196) zinc finger MIZ domain-co ( 894) 307 60.8 2.4e-08
XP_011513868 (OMIM: 611196) PREDICTED: zinc finger ( 655) 300 59.7 4e-08
XP_005249928 (OMIM: 611196) PREDICTED: zinc finger ( 897) 300 59.7 5.2e-08
XP_005249924 (OMIM: 611196) PREDICTED: zinc finger ( 929) 300 59.7 5.4e-08
XP_005249925 (OMIM: 611196) PREDICTED: zinc finger ( 929) 300 59.7 5.4e-08
XP_005249923 (OMIM: 611196) PREDICTED: zinc finger ( 929) 300 59.7 5.4e-08
XP_016868163 (OMIM: 611196) PREDICTED: zinc finger ( 929) 300 59.7 5.4e-08
XP_005249930 (OMIM: 611196) PREDICTED: zinc finger ( 888) 284 57.2 3.1e-07
>>NP_057250 (OMIM: 603566) E3 SUMO-protein ligase PIAS1 (651 aa)
initn: 4330 init1: 4330 opt: 4330 Z-score: 3753.3 bits: 704.8 E(85289): 2.5e-202
Smith-Waterman score: 4330; 100.0% identity (100.0% similar) in 651 aa overlap (1-651:1-651)
10 20 30 40 50 60
pF1KE2 MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 YRRRFPQKIMTPADLSIPNVHSSPMPATLSPSTIPQLTYDGHPASSPLLPVSLLGPKHEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 YRRRFPQKIMTPADLSIPNVHSSPMPATLSPSTIPQLTYDGHPASSPLLPVSLLGPKHEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 ELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFRETCFAFALTPQQVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 ELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFRETCFAFALTPQQVQQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 ISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPTKNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 ISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPTKNG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRNYSMAVYLVKQLSSTVLLQRLRAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 VEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRNYSMAVYLVKQLSSTVLLQRLRAK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 GIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 GIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDAT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 LYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYCTDCDEIQFKEDGTWAPMRSKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 LYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYCTDCDEIQFKEDGTWAPMRSKK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 EVQEVSASYNGVDGCLSSTLEHQVASHHQSSNKNKKVEVIDLTIDSSSDEEEEEPSAKRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 EVQEVSASYNGVDGCLSSTLEHQVASHHQSSNKNKKVEVIDLTIDSSSDEEEEEPSAKRT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 CPSLSPTSPLNNKGILSLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPFHMTPMPYDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 CPSLSPTSPLNNKGILSLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPFHMTPMPYDL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 QGLDFFPFLSGDNQHYNTSLLAAAAAAVSDDQDLLHSSRFFPYTSSQMFLDQLSAGGSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 QGLDFFPFLSGDNQHYNTSLLAAAAAAVSDDQDLLHSSRFFPYTSSQMFLDQLSAGGSTS
550 560 570 580 590 600
610 620 630 640 650
pF1KE2 LPTTNGSSSGSNSSLVSSNSLRESHSHTVTNRSSTDTASIFGIIPDIISLD
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 LPTTNGSSSGSNSSLVSSNSLRESHSHTVTNRSSTDTASIFGIIPDIISLD
610 620 630 640 650
>>NP_001307616 (OMIM: 603566) E3 SUMO-protein ligase PIA (653 aa)
initn: 4290 init1: 4290 opt: 4291 Z-score: 3719.6 bits: 698.5 E(85289): 1.9e-200
Smith-Waterman score: 4291; 99.2% identity (99.5% similar) in 651 aa overlap (1-651:4-653)
10 20 30 40 50
pF1KE2 MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKI
. :: .::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFTLQDSY-VKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKI
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 KELYRRRFPQKIMTPADLSIPNVHSSPMPATLSPSTIPQLTYDGHPASSPLLPVSLLGPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KELYRRRFPQKIMTPADLSIPNVHSSPMPATLSPSTIPQLTYDGHPASSPLLPVSLLGPK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 HELELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFRETCFAFALTPQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HELELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFRETCFAFALTPQQ
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE2 VQQISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQQISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPT
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE2 KNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRNYSMAVYLVKQLSSTVLLQRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRNYSMAVYLVKQLSSTVLLQRL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE2 RAKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCF
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE2 DATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYCTDCDEIQFKEDGTWAPMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYCTDCDEIQFKEDGTWAPMR
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE2 SKKEVQEVSASYNGVDGCLSSTLEHQVASHHQSSNKNKKVEVIDLTIDSSSDEEEEEPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKKEVQEVSASYNGVDGCLSSTLEHQVASHHQSSNKNKKVEVIDLTIDSSSDEEEEEPSA
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE2 KRTCPSLSPTSPLNNKGILSLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPFHMTPMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRTCPSLSPTSPLNNKGILSLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPFHMTPMP
480 490 500 510 520 530
540 550 560 570 580 590
pF1KE2 YDLQGLDFFPFLSGDNQHYNTSLLAAAAAAVSDDQDLLHSSRFFPYTSSQMFLDQLSAGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YDLQGLDFFPFLSGDNQHYNTSLLAAAAAAVSDDQDLLHSSRFFPYTSSQMFLDQLSAGG
540 550 560 570 580 590
600 610 620 630 640 650
pF1KE2 STSLPTTNGSSSGSNSSLVSSNSLRESHSHTVTNRSSTDTASIFGIIPDIISLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STSLPTTNGSSSGSNSSLVSSNSLRESHSHTVTNRSSTDTASIFGIIPDIISLD
600 610 620 630 640 650
>>XP_016878177 (OMIM: 603566) PREDICTED: E3 SUMO-protein (653 aa)
initn: 4290 init1: 4290 opt: 4291 Z-score: 3719.6 bits: 698.5 E(85289): 1.9e-200
Smith-Waterman score: 4291; 99.2% identity (99.5% similar) in 651 aa overlap (1-651:4-653)
10 20 30 40 50
pF1KE2 MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKI
. :: .::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MFTLQDSY-VKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKI
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 KELYRRRFPQKIMTPADLSIPNVHSSPMPATLSPSTIPQLTYDGHPASSPLLPVSLLGPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KELYRRRFPQKIMTPADLSIPNVHSSPMPATLSPSTIPQLTYDGHPASSPLLPVSLLGPK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 HELELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFRETCFAFALTPQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HELELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFRETCFAFALTPQQ
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE2 VQQISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQQISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPT
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE2 KNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRNYSMAVYLVKQLSSTVLLQRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRNYSMAVYLVKQLSSTVLLQRL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE2 RAKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCF
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE2 DATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYCTDCDEIQFKEDGTWAPMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYCTDCDEIQFKEDGTWAPMR
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE2 SKKEVQEVSASYNGVDGCLSSTLEHQVASHHQSSNKNKKVEVIDLTIDSSSDEEEEEPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKKEVQEVSASYNGVDGCLSSTLEHQVASHHQSSNKNKKVEVIDLTIDSSSDEEEEEPSA
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE2 KRTCPSLSPTSPLNNKGILSLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPFHMTPMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRTCPSLSPTSPLNNKGILSLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPFHMTPMP
480 490 500 510 520 530
540 550 560 570 580 590
pF1KE2 YDLQGLDFFPFLSGDNQHYNTSLLAAAAAAVSDDQDLLHSSRFFPYTSSQMFLDQLSAGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YDLQGLDFFPFLSGDNQHYNTSLLAAAAAAVSDDQDLLHSSRFFPYTSSQMFLDQLSAGG
540 550 560 570 580 590
600 610 620 630 640 650
pF1KE2 STSLPTTNGSSSGSNSSLVSSNSLRESHSHTVTNRSSTDTASIFGIIPDIISLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STSLPTTNGSSSGSNSSLVSSNSLRESHSHTVTNRSSTDTASIFGIIPDIISLD
600 610 620 630 640 650
>>XP_011520429 (OMIM: 603566) PREDICTED: E3 SUMO-protein (645 aa)
initn: 4287 init1: 4287 opt: 4287 Z-score: 3716.2 bits: 697.9 E(85289): 3e-200
Smith-Waterman score: 4287; 99.7% identity (100.0% similar) in 645 aa overlap (7-651:1-645)
10 20 30 40 50 60
pF1KE2 MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKEL
..::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKEL
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 YRRRFPQKIMTPADLSIPNVHSSPMPATLSPSTIPQLTYDGHPASSPLLPVSLLGPKHEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YRRRFPQKIMTPADLSIPNVHSSPMPATLSPSTIPQLTYDGHPASSPLLPVSLLGPKHEL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE2 ELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFRETCFAFALTPQQVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFRETCFAFALTPQQVQQ
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE2 ISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPTKNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPTKNG
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE2 VEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRNYSMAVYLVKQLSSTVLLQRLRAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRNYSMAVYLVKQLSSTVLLQRLRAK
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE2 GIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDAT
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE2 LYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYCTDCDEIQFKEDGTWAPMRSKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYCTDCDEIQFKEDGTWAPMRSKK
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE2 EVQEVSASYNGVDGCLSSTLEHQVASHHQSSNKNKKVEVIDLTIDSSSDEEEEEPSAKRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVQEVSASYNGVDGCLSSTLEHQVASHHQSSNKNKKVEVIDLTIDSSSDEEEEEPSAKRT
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE2 CPSLSPTSPLNNKGILSLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPFHMTPMPYDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CPSLSPTSPLNNKGILSLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPFHMTPMPYDL
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE2 QGLDFFPFLSGDNQHYNTSLLAAAAAAVSDDQDLLHSSRFFPYTSSQMFLDQLSAGGSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGLDFFPFLSGDNQHYNTSLLAAAAAAVSDDQDLLHSSRFFPYTSSQMFLDQLSAGGSTS
540 550 560 570 580 590
610 620 630 640 650
pF1KE2 LPTTNGSSSGSNSSLVSSNSLRESHSHTVTNRSSTDTASIFGIIPDIISLD
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPTTNGSSSGSNSSLVSSNSLRESHSHTVTNRSSTDTASIFGIIPDIISLD
600 610 620 630 640
>>XP_016878178 (OMIM: 603566) PREDICTED: E3 SUMO-protein (644 aa)
initn: 4283 init1: 4283 opt: 4283 Z-score: 3712.7 bits: 697.2 E(85289): 4.6e-200
Smith-Waterman score: 4283; 100.0% identity (100.0% similar) in 643 aa overlap (9-651:2-644)
10 20 30 40 50 60
pF1KE2 MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKEL
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 YRRRFPQKIMTPADLSIPNVHSSPMPATLSPSTIPQLTYDGHPASSPLLPVSLLGPKHEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YRRRFPQKIMTPADLSIPNVHSSPMPATLSPSTIPQLTYDGHPASSPLLPVSLLGPKHEL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE2 ELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFRETCFAFALTPQQVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFRETCFAFALTPQQVQQ
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE2 ISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPTKNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPTKNG
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE2 VEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRNYSMAVYLVKQLSSTVLLQRLRAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRNYSMAVYLVKQLSSTVLLQRLRAK
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE2 GIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDAT
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE2 LYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYCTDCDEIQFKEDGTWAPMRSKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYCTDCDEIQFKEDGTWAPMRSKK
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE2 EVQEVSASYNGVDGCLSSTLEHQVASHHQSSNKNKKVEVIDLTIDSSSDEEEEEPSAKRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVQEVSASYNGVDGCLSSTLEHQVASHHQSSNKNKKVEVIDLTIDSSSDEEEEEPSAKRT
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE2 CPSLSPTSPLNNKGILSLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPFHMTPMPYDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CPSLSPTSPLNNKGILSLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPFHMTPMPYDL
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE2 QGLDFFPFLSGDNQHYNTSLLAAAAAAVSDDQDLLHSSRFFPYTSSQMFLDQLSAGGSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGLDFFPFLSGDNQHYNTSLLAAAAAAVSDDQDLLHSSRFFPYTSSQMFLDQLSAGGSTS
540 550 560 570 580 590
610 620 630 640 650
pF1KE2 LPTTNGSSSGSNSSLVSSNSLRESHSHTVTNRSSTDTASIFGIIPDIISLD
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPTTNGSSSGSNSSLVSSNSLRESHSHTVTNRSSTDTASIFGIIPDIISLD
600 610 620 630 640
>>XP_011520428 (OMIM: 603566) PREDICTED: E3 SUMO-protein (660 aa)
initn: 4283 init1: 4283 opt: 4283 Z-score: 3712.6 bits: 697.2 E(85289): 4.7e-200
Smith-Waterman score: 4283; 100.0% identity (100.0% similar) in 643 aa overlap (9-651:18-660)
10 20 30 40 50
pF1KE2 MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSP
:::::::::::::::::::::::::::::::::::::::::::
XP_011 MKLNGKRNHNYKSYYECQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 AVQMKIKELYRRRFPQKIMTPADLSIPNVHSSPMPATLSPSTIPQLTYDGHPASSPLLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVQMKIKELYRRRFPQKIMTPADLSIPNVHSSPMPATLSPSTIPQLTYDGHPASSPLLPV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 SLLGPKHELELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFRETCFAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLLGPKHELELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFRETCFAF
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE2 ALTPQQVQQISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALTPQQVQQISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLP
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE2 GYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRNYSMAVYLVKQLSST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRNYSMAVYLVKQLSST
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE2 VLLQRLRAKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLLQRLRAKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTC
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE2 SHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYCTDCDEIQFKEDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYCTDCDEIQFKEDG
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE2 TWAPMRSKKEVQEVSASYNGVDGCLSSTLEHQVASHHQSSNKNKKVEVIDLTIDSSSDEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TWAPMRSKKEVQEVSASYNGVDGCLSSTLEHQVASHHQSSNKNKKVEVIDLTIDSSSDEE
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE2 EEEPSAKRTCPSLSPTSPLNNKGILSLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEEPSAKRTCPSLSPTSPLNNKGILSLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPF
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE2 HMTPMPYDLQGLDFFPFLSGDNQHYNTSLLAAAAAAVSDDQDLLHSSRFFPYTSSQMFLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HMTPMPYDLQGLDFFPFLSGDNQHYNTSLLAAAAAAVSDDQDLLHSSRFFPYTSSQMFLD
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE2 QLSAGGSTSLPTTNGSSSGSNSSLVSSNSLRESHSHTVTNRSSTDTASIFGIIPDIISLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLSAGGSTSLPTTNGSSSGSNSSLVSSNSLRESHSHTVTNRSSTDTASIFGIIPDIISLD
610 620 630 640 650 660
>>XP_016878180 (OMIM: 603566) PREDICTED: E3 SUMO-protein (642 aa)
initn: 4276 init1: 4276 opt: 4276 Z-score: 3706.7 bits: 696.1 E(85289): 1e-199
Smith-Waterman score: 4276; 100.0% identity (100.0% similar) in 642 aa overlap (10-651:1-642)
10 20 30 40 50 60
pF1KE2 MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKEL
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKEL
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 YRRRFPQKIMTPADLSIPNVHSSPMPATLSPSTIPQLTYDGHPASSPLLPVSLLGPKHEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YRRRFPQKIMTPADLSIPNVHSSPMPATLSPSTIPQLTYDGHPASSPLLPVSLLGPKHEL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE2 ELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFRETCFAFALTPQQVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFRETCFAFALTPQQVQQ
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE2 ISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPTKNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPTKNG
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE2 VEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRNYSMAVYLVKQLSSTVLLQRLRAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRNYSMAVYLVKQLSSTVLLQRLRAK
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE2 GIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDAT
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE2 LYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYCTDCDEIQFKEDGTWAPMRSKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYCTDCDEIQFKEDGTWAPMRSKK
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE2 EVQEVSASYNGVDGCLSSTLEHQVASHHQSSNKNKKVEVIDLTIDSSSDEEEEEPSAKRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVQEVSASYNGVDGCLSSTLEHQVASHHQSSNKNKKVEVIDLTIDSSSDEEEEEPSAKRT
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE2 CPSLSPTSPLNNKGILSLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPFHMTPMPYDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CPSLSPTSPLNNKGILSLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPFHMTPMPYDL
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE2 QGLDFFPFLSGDNQHYNTSLLAAAAAAVSDDQDLLHSSRFFPYTSSQMFLDQLSAGGSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGLDFFPFLSGDNQHYNTSLLAAAAAAVSDDQDLLHSSRFFPYTSSQMFLDQLSAGGSTS
540 550 560 570 580 590
610 620 630 640 650
pF1KE2 LPTTNGSSSGSNSSLVSSNSLRESHSHTVTNRSSTDTASIFGIIPDIISLD
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPTTNGSSSGSNSSLVSSNSLRESHSHTVTNRSSTDTASIFGIIPDIISLD
600 610 620 630 640
>>XP_016878179 (OMIM: 603566) PREDICTED: E3 SUMO-protein (642 aa)
initn: 4276 init1: 4276 opt: 4276 Z-score: 3706.7 bits: 696.1 E(85289): 1e-199
Smith-Waterman score: 4276; 100.0% identity (100.0% similar) in 642 aa overlap (10-651:1-642)
10 20 30 40 50 60
pF1KE2 MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKEL
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKEL
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 YRRRFPQKIMTPADLSIPNVHSSPMPATLSPSTIPQLTYDGHPASSPLLPVSLLGPKHEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YRRRFPQKIMTPADLSIPNVHSSPMPATLSPSTIPQLTYDGHPASSPLLPVSLLGPKHEL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE2 ELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFRETCFAFALTPQQVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFRETCFAFALTPQQVQQ
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE2 ISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPTKNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPTKNG
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE2 VEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRNYSMAVYLVKQLSSTVLLQRLRAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRNYSMAVYLVKQLSSTVLLQRLRAK
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE2 GIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDAT
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE2 LYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYCTDCDEIQFKEDGTWAPMRSKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYCTDCDEIQFKEDGTWAPMRSKK
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE2 EVQEVSASYNGVDGCLSSTLEHQVASHHQSSNKNKKVEVIDLTIDSSSDEEEEEPSAKRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVQEVSASYNGVDGCLSSTLEHQVASHHQSSNKNKKVEVIDLTIDSSSDEEEEEPSAKRT
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE2 CPSLSPTSPLNNKGILSLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPFHMTPMPYDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CPSLSPTSPLNNKGILSLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPFHMTPMPYDL
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE2 QGLDFFPFLSGDNQHYNTSLLAAAAAAVSDDQDLLHSSRFFPYTSSQMFLDQLSAGGSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGLDFFPFLSGDNQHYNTSLLAAAAAAVSDDQDLLHSSRFFPYTSSQMFLDQLSAGGSTS
540 550 560 570 580 590
610 620 630 640 650
pF1KE2 LPTTNGSSSGSNSSLVSSNSLRESHSHTVTNRSSTDTASIFGIIPDIISLD
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPTTNGSSSGSNSSLVSSNSLRESHSHTVTNRSSTDTASIFGIIPDIISLD
600 610 620 630 640
>>NP_006090 (OMIM: 605987) E3 SUMO-protein ligase PIAS3 (628 aa)
initn: 1958 init1: 1388 opt: 2303 Z-score: 2000.0 bits: 380.3 E(85289): 1.2e-104
Smith-Waterman score: 2375; 57.9% identity (78.4% similar) in 663 aa overlap (1-651:1-628)
10 20 30 40 50 60
pF1KE2 MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKEL
::. .:::.::::.::::::::::.::::: :::::::.:::::::..:.:.::::::::
NP_006 MAELGELKHMVMSFRVSELQVLLGFAGRNKSGRKHELLAKALHLLKSSCAPSVQMKIKEL
10 20 30 40 50 60
70 80 90 100 110
pF1KE2 YRRRFPQKIMTPADLSIPNVH--SSPM--PATLSPSTIPQLTYDGHPASSPLLPVSLLGP
::::::.: . :.:::. .. .::. :. :.: :: : . : : .::::
NP_006 YRRRFPRKTLGPSDLSLLSLPPGTSPVGSPGPLAP--IP-------P--TLLAPGTLLGP
70 80 90 100
120 130 140 150 160 170
pF1KE2 KHELEL-PHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFRETCFAFALTP
:.:... : : .:::::. .. ::::.. :::.::.::: .::::.:. :.:::::
NP_006 KREVDMHPPLP---QPVHPDVTMKPLPFYEVYGELIRPTTLASTSSQRFEEAHFTFALTP
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE2 QQVQQISSSMDI-SGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYL
:::::: .: .. :.:::.:.:::::::: ::::::::.::::: :::: : : :::::
NP_006 QQVQQILTSREVLPGAKCDYTIQVQLRFCLCETSCPQEDYFPPNLFVKVNGKLCPLPGYL
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE2 PPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRNYSMAVYLVKQLSSTVLL
::::::.:::::::::::: :.:::.::::::::.:..:.:::::..::::.::.. .::
NP_006 PPTKNGAEPKRPSRPINITPLARLSATVPNTIVVNWSSEFGRNYSLSVYLVRQLTAGTLL
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE2 QRLRAKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHL
:.:::::::::::::::::::::::::::.:::::::::.:::::::::.:::::::.::
NP_006 QKLRAKGIRNPDHSRALIKEKLTADPDSEVATTSLRVSLMCPLGKMRLTVPCRALTCAHL
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE2 QCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYCTDCDEIQFKEDGTWA
: :::.::.:::::::::.::::::::::: :::::::::::. :.::::::: :::.:
NP_006 QSFDAALYLQMNEKKPTWTCPVCDKKAPYESLIIDGLFMEILSSCSDCDEIQFMEDGSWC
350 360 370 380 390 400
420 430 440 450 460 470
pF1KE2 PMRSKKEVQEVSASYN-GVDGCLSSTLEHQVASHHQSSNKNKKVEVIDLTIDSSSDEEEE
::. :::..:: . :.:: :... .. . :...::::::::::.::::::.
NP_006 PMKPKKEASEVCPPPGYGLDG-----LQYSPVQGGDPSENKKKVEVIDLTIESSSDEEDL
410 420 430 440 450 460
480 490 500 510 520 530
pF1KE2 EPSAKRTCPSLSPTSPL--NNKGILSLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPF
:. :. : : . : ..::.:. :: : : :.:.. .. ..... ...: :
NP_006 PPT-KKHCSVTSAAIPALPGSKGVLTSGHQPSSVLRSPAMGTLGGDFLSSLPLHEYPPAF
470 480 490 500 510 520
540 550 560 570 580 590
pF1KE2 HMTPMPYDLQGLDFFPFLSGDNQHYNTSLLAAAAAAVSDDQDLLHSSRFFPYTSS-QMFL
:. :.::::.: ::. ..:::. :.... :.:: : ..:: : .. . ::
NP_006 ---PLGADIQGLDLFSFLQTESQHYGPSVITSL-----DEQDAL--GHFFQYRGTPSHFL
530 540 550 560 570
600 610 620 630 640
pF1KE2 DQLSAG-GSTSLPTTNGSSSGSNSSLVS-SNSLRESHSHTVTNRSSTDTASIFGIIPDII
:. ::. .: . : ::.:. ...:::.:. . . :. : :::
NP_006 GPLAPTLGSSHCSATPAPPPGRVSSIVAPGGALREGHGGPLPS-----GPSLTGCRSDII
580 590 600 610 620
650
pF1KE2 SLD
:::
NP_006 SLD
>>XP_011524561 (OMIM: 603567) PREDICTED: E3 SUMO-protein (613 aa)
initn: 2120 init1: 1304 opt: 1853 Z-score: 1610.8 bits: 308.2 E(85289): 5.5e-83
Smith-Waterman score: 2175; 55.5% identity (73.3% similar) in 656 aa overlap (10-651:1-613)
10 20 30 40 50 60
pF1KE2 MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKEL
:: :.::::::::::.::::: ::::.:: .::::::.:::::::.::.::
XP_011 MVSSFRVSELQVLLGFAGRNKSGRKHDLLMRALHLLKSGCSPAVQIKIREL
10 20 30 40 50
70 80 90 100 110
pF1KE2 YRRRFPQKIMTPADLSIPNVH-------SSPMPATLSPS---TIPQLTYDGHPASSPLLP
::::.:. . .::: . :::. :. . ..:. . : :::.
XP_011 YRRRYPRTLEGLSDLSTIKSSVFSLDGGSSPVEPDLAVAGIHSLPSTSVTPHSPSSPVGS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 VSLLGPKHELELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFRETCFA
: : : .:. . . . :::::..:..:::::.:: :::::::.... :::.: :
XP_011 VLLQDTKPTFEMQQPSPPIPPVHPDVQLKNLPFYDVLDVLIKPTSLVQSSIQRFQEKFFI
120 130 140 150 160 170
180 190 200 210 220
pF1KE2 FALTPQQVQQISSSMD-ISGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCS
::::::::..: : : . : . :.:::::::.::.::::::::..: .::.::: :
XP_011 FALTPQQVREICISRDFLPGGRRDYTVQVQLRLCLAETSCPQEDNYPNSLCIKVNGKLFP
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE2 LPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRNYSMAVYLVKQLS
:::: :: :::.: :::.::.:::::::::..::: : .::..:::.::::.::::.::.
XP_011 LPGYAPPPKNGIEQKRPGRPLNITSLVRLSSAVPNQISISWASEIGKNYSMSVYLVRQLT
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE2 STVLLQRLRAKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRAL
:..:::::. ::::::::::::::::::::::::::::::::::.::::::::::::::.
XP_011 SAMLLQRLKMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLGKMRLTIPCRAV
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE2 TCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYCTDCDEIQFKE
::.:::::::.::.:::::::::.:::::::: :: ::.::::::::. :.: :::.:.:
XP_011 TCTHLQCFDAALYLQMNEKKPTWICPVCDKKAAYESLILDGLFMEILNDCSDVDEIKFQE
360 370 380 390 400 410
410 420 430 440 450 460
pF1KE2 DGTWAPMRSKKEVQEVSASYNGVDGCLSSTLEHQVASHHQSSNKNKKVEVIDLTIDSSSD
::.: ::: :::...:: : . ::.: . . : ..:::.::::::.::::
XP_011 DGSWCPMRPKKEAMKVS-SQPCTKIESSSVLSKPCSVTVASEASKKKVDVIDLTIESSSD
420 430 440 450 460 470
470 480 490 500 510 520
pF1KE2 EEEEEPSAKRTCPSLSPTSPLNNKGILSLPHQASPVSRTPSLPAVDTSYINTSLIQDYRH
:::. : ::: : .: :. .::.: .: : : :.::. .:: . : :: ::
XP_011 EEEDPP-AKRKCIFMSETQSSPTKGVLM--YQPSSV-RVPSVTSVDPAAIPPSLT-DYSV
480 490 500 510 520
530 540 550 560 570 580
pF1KE2 PFHMTP---MPYDLQGLDFFPFLSGDNQHYNTSLLAAAAAAVSDDQDLLHSSRFFPYTSS
::: :: : :: ::::. .. : :.: :
XP_011 PFHHTPISSMSSDLPGLDFLSLIPVDPQQYCP-----------------------P----
530 540 550
590 600 610 620 630 640
pF1KE2 QMFLDQLSAGGSTSLPTTNGSSSGSNSSLVSSNSLRESHSHTVTNRSSTDTASIFGIIPD
::::.:.. ..: ... .:: .:. :::.: : :.. ..:. .:. :::
XP_011 -MFLDSLTSPLTASSTSVTTTSSHESSTHVSSSSSR-SETGVITSSGSN--------IPD
560 570 580 590 600
650
pF1KE2 IISLD
:::::
XP_011 IISLD
610
651 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 10:40:43 2016 done: Sun Nov 6 10:40:45 2016
Total Scan time: 10.620 Total Display time: 0.160
Function used was FASTA [36.3.4 Apr, 2011]