Result of FASTA (omim) for
pFN21AE2037
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2037, 634 aa
1>>>pF1KE2037 634 - 634 aa - 634 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.4795+/-0.000335; mu= 11.7779+/- 0.021
mean_var=178.2690+/-35.810, 0's: 0 Z-trim(120.9): 22 B-trim: 157 in 1/58
Lambda= 0.096059
statistics sampled from 36663 (36686) to 36663 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.752), E-opt: 0.2 (0.43), width: 16
Scan time: 12.750
The best scores are: opt bits E(85289)
NP_002085 (OMIM: 139259) eukaryotic peptide chain ( 637) 4271 604.2 4.4e-172
NP_001123478 (OMIM: 139259) eukaryotic peptide cha ( 636) 4254 601.9 2.2e-171
NP_060564 (OMIM: 300418) eukaryotic peptide chain ( 628) 3674 521.5 3.5e-147
NP_001123479 (OMIM: 139259) eukaryotic peptide cha ( 499) 3362 478.2 3.1e-134
NP_001138630 (OMIM: 612450) HBS1-like protein isof ( 642) 1162 173.4 2.2e-42
NP_006611 (OMIM: 612450) HBS1-like protein isoform ( 684) 1162 173.4 2.3e-42
XP_011533816 (OMIM: 130590) PREDICTED: elongation ( 462) 707 110.2 1.7e-23
NP_001393 (OMIM: 130590) elongation factor 1-alpha ( 462) 707 110.2 1.7e-23
NP_001949 (OMIM: 602959,616393,616409) elongation ( 463) 704 109.8 2.2e-23
NP_003312 (OMIM: 602389,610678) elongation factor ( 455) 272 49.9 2.3e-05
XP_016879108 (OMIM: 602389,610678) PREDICTED: elon ( 455) 272 49.9 2.3e-05
XP_011544230 (OMIM: 602389,610678) PREDICTED: elon ( 427) 235 44.8 0.00078
>>NP_002085 (OMIM: 139259) eukaryotic peptide chain rele (637 aa)
initn: 4257 init1: 4257 opt: 4271 Z-score: 3210.4 bits: 604.2 E(85289): 4.4e-172
Smith-Waterman score: 4271; 99.4% identity (99.4% similar) in 637 aa overlap (1-634:1-637)
10 20 30 40 50
pF1KE2 MDPGSGGGGGGGG---SSSGSSSSDSAPDCWDQADMEAPGPGPCGGGGSLAAAAEAQREN
::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::
NP_002 MDPGSGGGGGGGGGGGSSSGSSSSDSAPDCWDQADMEAPGPGPCGGGGSLAAAAEAQREN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 LSAAFSRQLNVNAKPFVPNVHAAEFVPSFLRCPAAPPPPAGGAANNHGAGSGAGGRAAPV
::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
NP_002 LSAAFSRQLNVNAKPFVPNVHAAEFVPSFLRGPAAPPPPAGGAANNHGAGSGAGGRAAPV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 ESSQEEQSLCEGSNSAVSMELSEPIVENGETEMSPEESWEHKEEISEAEPGGGSLGDGRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ESSQEEQSLCEGSNSAVSMELSEPIVENGETEMSPEESWEHKEEISEAEPGGGSLGDGRP
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE2 PEESAHEMMEEEEEIPKPKSVVAPPGAPKKEHVNVVFIGHVDAGKSTIGGQIMYLTGMVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PEESAHEMMEEEEEIPKPKSVVAPPGAPKKEHVNVVFIGHVDAGKSTIGGQIMYLTGMVD
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE2 KRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGH
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE2 KSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKM
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE2 DDPTVNWSNERYEECKEKLVPFLKKVGFNPKKDIHFMPCSGLTGANLKEQSDFCPWYIGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DDPTVNWSNERYEECKEKLVPFLKKVGFNPKKDIHFMPCSGLTGANLKEQSDFCPWYIGL
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE2 PFIPYLDNLPNFNRSVDGPIRLPIVDKYKDMGTVVLGKLESGSICKGQQLVMMPNKHNVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PFIPYLDNLPNFNRSVDGPIRLPIVDKYKDMGTVVLGKLESGSICKGQQLVMMPNKHNVE
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE2 VLGILSDDVETDTVAPGENLKIRLKGIEEEEILPGFILCDPNNLCHSGRTFDAQIVIIEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VLGILSDDVETDTVAPGENLKIRLKGIEEEEILPGFILCDPNNLCHSGRTFDAQIVIIEH
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE2 KSIICPGYNAVLHIHTCIEEVEITALICLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KSIICPGYNAVLHIHTCIEEVEITALICLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGT
550 560 570 580 590 600
600 610 620 630
pF1KE2 ICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD
:::::::::::::::::::::::::::::::::::::
NP_002 ICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD
610 620 630
>>NP_001123478 (OMIM: 139259) eukaryotic peptide chain r (636 aa)
initn: 3389 init1: 3389 opt: 4254 Z-score: 3197.7 bits: 601.9 E(85289): 2.2e-171
Smith-Waterman score: 4254; 99.2% identity (99.2% similar) in 637 aa overlap (1-634:1-636)
10 20 30 40 50
pF1KE2 MDPGSGGGGGGGG---SSSGSSSSDSAPDCWDQADMEAPGPGPCGGGGSLAAAAEAQREN
::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDPGSGGGGGGGGGGGSSSGSSSSDSAPDCWDQADMEAPGPGPCGGGGSLAAAAEAQREN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 LSAAFSRQLNVNAKPFVPNVHAAEFVPSFLRCPAAPPPPAGGAANNHGAGSGAGGRAAPV
::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
NP_001 LSAAFSRQLNVNAKPFVPNVHAAEFVPSFLRGPAAPPPPAGGAANNHGAGSGAGGRAAPV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 ESSQEEQSLCEGSNSAVSMELSEPIVENGETEMSPEESWEHKEEISEAEPGGGSLGDGRP
::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
NP_001 ESSQEEQSLCEGSNSAVSMELSEPI-ENGETEMSPEESWEHKEEISEAEPGGGSLGDGRP
130 140 150 160 170
180 190 200 210 220 230
pF1KE2 PEESAHEMMEEEEEIPKPKSVVAPPGAPKKEHVNVVFIGHVDAGKSTIGGQIMYLTGMVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEESAHEMMEEEEEIPKPKSVVAPPGAPKKEHVNVVFIGHVDAGKSTIGGQIMYLTGMVD
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE2 KRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGH
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE2 KSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKM
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE2 DDPTVNWSNERYEECKEKLVPFLKKVGFNPKKDIHFMPCSGLTGANLKEQSDFCPWYIGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDPTVNWSNERYEECKEKLVPFLKKVGFNPKKDIHFMPCSGLTGANLKEQSDFCPWYIGL
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE2 PFIPYLDNLPNFNRSVDGPIRLPIVDKYKDMGTVVLGKLESGSICKGQQLVMMPNKHNVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PFIPYLDNLPNFNRSVDGPIRLPIVDKYKDMGTVVLGKLESGSICKGQQLVMMPNKHNVE
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE2 VLGILSDDVETDTVAPGENLKIRLKGIEEEEILPGFILCDPNNLCHSGRTFDAQIVIIEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLGILSDDVETDTVAPGENLKIRLKGIEEEEILPGFILCDPNNLCHSGRTFDAQIVIIEH
480 490 500 510 520 530
540 550 560 570 580 590
pF1KE2 KSIICPGYNAVLHIHTCIEEVEITALICLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSIICPGYNAVLHIHTCIEEVEITALICLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGT
540 550 560 570 580 590
600 610 620 630
pF1KE2 ICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD
:::::::::::::::::::::::::::::::::::::
NP_001 ICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD
600 610 620 630
>>NP_060564 (OMIM: 300418) eukaryotic peptide chain rele (628 aa)
initn: 3523 init1: 3198 opt: 3674 Z-score: 2763.4 bits: 521.5 E(85289): 3.5e-147
Smith-Waterman score: 3674; 88.5% identity (94.4% similar) in 627 aa overlap (16-634:3-628)
10 20 30 40 50 60
pF1KE2 MDPGSGGGGGGGGSSSGSSSSDSAPDCWDQADMEAPGPGPCGGGGSLAAAAEAQRENLSA
:::::::::::::::.:::.:: .: : : : .:.:::::: ::.
NP_060 MDSGSSSSDSAPDCWDQVDMESPGSAPSGDGVS-SAVAEAQREPLSS
10 20 30 40
70 80 90 100 110
pF1KE2 AFSRQLNVNAKPFVPNVHAAEFVPSFLRCPAAPPP-PAGGAANNH---GAGSGAG---GR
::::.::::::::::::::::::::::: :. :: :::...:.. ::: : ::
NP_060 AFSRKLNVNAKPFVPNVHAAEFVPSFLRGPTQPPTLPAGSGSNDETCTGAGYPQGKRMGR
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE2 AAPVESSQEEQSLC-EGSNSAVSMELSEPIVENGETEMSPEESWEHKEEISEAEPGGGSL
.:::: :.:: . :::::::.::::::.:::::.::. ::::::..:.:::::::::
NP_060 GAPVEPSREEPLVSLEGSNSAVTMELSEPVVENGEVEMALEESWEHSKEVSEAEPGGGSS
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE2 GDGRPPEESAHEMMEEEEEIPKPKSVVAPPGAPKKEHVNVVFIGHVDAGKSTIGGQIMYL
::. :::::..:::::.::: : :::..: ::::::::::::::::::::::::::::.:
NP_060 GDSGPPEESGQEMMEEKEEIRKSKSVIVPSGAPKKEHVNVVFIGHVDAGKSTIGGQIMFL
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE2 TGMVDKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTIL
:::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::
NP_060 TGMVDKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETERKHFTIL
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE2 DAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 DAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIV
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE2 LINKMDDPTVNWSNERYEECKEKLVPFLKKVGFNPKKDIHFMPCSGLTGANLKEQSDFCP
::::::::::::: :::::::::::::::::::.:::::::::::::::::.::::::::
NP_060 LINKMDDPTVNWSIERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQSDFCP
350 360 370 380 390 400
420 430 440 450 460 470
pF1KE2 WYIGLPFIPYLDNLPNFNRSVDGPIRLPIVDKYKDMGTVVLGKLESGSICKGQQLVMMPN
:: :::::::::::::::::.:::::::::::::::::::::::::::: ::::::::::
NP_060 WYTGLPFIPYLDNLPNFNRSIDGPIRLPIVDKYKDMGTVVLGKLESGSIFKGQQLVMMPN
410 420 430 440 450 460
480 490 500 510 520 530
pF1KE2 KHNVEVLGILSDDVETDTVAPGENLKIRLKGIEEEEILPGFILCDPNNLCHSGRTFDAQI
:::::::::::::.::: ::::::::::::::::::::::::::::.::::::::::.::
NP_060 KHNVEVLGILSDDTETDFVAPGENLKIRLKGIEEEEILPGFILCDPSNLCHSGRTFDVQI
470 480 490 500 510 520
540 550 560 570 580 590
pF1KE2 VIIEHKSIICPGYNAVLHIHTCIEEVEITALICLVDKKSGEKSKTRPRFVKQDQVCIARL
:::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::
NP_060 VIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQDQVCIARL
530 540 550 560 570 580
600 610 620 630
pF1KE2 RTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD
::::::::::::::::::::::::::::::::::::::::::
NP_060 RTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD
590 600 610 620
>>NP_001123479 (OMIM: 139259) eukaryotic peptide chain r (499 aa)
initn: 3362 init1: 3362 opt: 3362 Z-score: 2531.0 bits: 478.2 E(85289): 3.1e-134
Smith-Waterman score: 3362; 100.0% identity (100.0% similar) in 499 aa overlap (136-634:1-499)
110 120 130 140 150 160
pF1KE2 AGSGAGGRAAPVESSQEEQSLCEGSNSAVSMELSEPIVENGETEMSPEESWEHKEEISEA
::::::::::::::::::::::::::::::
NP_001 MELSEPIVENGETEMSPEESWEHKEEISEA
10 20 30
170 180 190 200 210 220
pF1KE2 EPGGGSLGDGRPPEESAHEMMEEEEEIPKPKSVVAPPGAPKKEHVNVVFIGHVDAGKSTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPGGGSLGDGRPPEESAHEMMEEEEEIPKPKSVVAPPGAPKKEHVNVVFIGHVDAGKSTI
40 50 60 70 80 90
230 240 250 260 270 280
pF1KE2 GGQIMYLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGQIMYLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETE
100 110 120 130 140 150
290 300 310 320 330 340
pF1KE2 KKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTA
160 170 180 190 200 210
350 360 370 380 390 400
pF1KE2 GVKHLIVLINKMDDPTVNWSNERYEECKEKLVPFLKKVGFNPKKDIHFMPCSGLTGANLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVKHLIVLINKMDDPTVNWSNERYEECKEKLVPFLKKVGFNPKKDIHFMPCSGLTGANLK
220 230 240 250 260 270
410 420 430 440 450 460
pF1KE2 EQSDFCPWYIGLPFIPYLDNLPNFNRSVDGPIRLPIVDKYKDMGTVVLGKLESGSICKGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQSDFCPWYIGLPFIPYLDNLPNFNRSVDGPIRLPIVDKYKDMGTVVLGKLESGSICKGQ
280 290 300 310 320 330
470 480 490 500 510 520
pF1KE2 QLVMMPNKHNVEVLGILSDDVETDTVAPGENLKIRLKGIEEEEILPGFILCDPNNLCHSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLVMMPNKHNVEVLGILSDDVETDTVAPGENLKIRLKGIEEEEILPGFILCDPNNLCHSG
340 350 360 370 380 390
530 540 550 560 570 580
pF1KE2 RTFDAQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALICLVDKKSGEKSKTRPRFVKQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTFDAQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALICLVDKKSGEKSKTRPRFVKQD
400 410 420 430 440 450
590 600 610 620 630
pF1KE2 QVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD
460 470 480 490
>>NP_001138630 (OMIM: 612450) HBS1-like protein isoform (642 aa)
initn: 926 init1: 637 opt: 1162 Z-score: 881.8 bits: 173.4 E(85289): 2.2e-42
Smith-Waterman score: 1170; 37.3% identity (66.5% similar) in 549 aa overlap (107-629:97-640)
80 90 100 110 120 130
pF1KE2 VHAAEFVPSFLRCPAAPPPPAGGAANNHGAGSGAGGRAAPVESSQEEQSLCEG------S
:. : :. . ..:. :. . :
NP_001 KFDVQKALSGVLEQDRVQSLKDKNEATVSTGKIAKGKPVDSQTSRSESEIVPKVAKMTVS
70 80 90 100 110 120
140 150 160 170 180
pF1KE2 NSAVSMELSEPIV---ENGETEMSPEESWEHKEEISEAEPGGGSLGDGRPPEESAHEMME
.. .: . : : :::.. .:... .. :. .. . .. ::. . :
NP_001 GKKQTMGFEVPGVSSEENGHSFHTPQKGPPIEDAIASSDVLETASKSANPPHTI--QASE
130 140 150 160 170 180
190 200 210 220 230
pF1KE2 EEEEIPKP--------KSVVAPPGAPK----KEHVNVVFIGHVDAGKSTIGGQIMYLTGM
:. : : ... . : :. .:.: ::::::::::. :...:: :
NP_001 EQSSTPAPVKKSGKLRQQIDVKAELEKRQGGKQLLNLVVIGHVDAGKSTLMGHMLYLLGN
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE2 VDKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAP
..:::..:::.:.:. .. .. .:.:: . :::..: :..:: . ::: : .:..:::
NP_001 INKRTMHKYEQESKKAGKASFAYAWVLDETGEERERGVTMDVGMTKFETTTKVITLMDAP
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE2 GHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLIN
:::.:.:::: ::.:::.::::..: .::::.::: :::::::..:... :: .: : .:
NP_001 GHKDFIPNMITGAAQADVAVLVVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLAVAVN
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE2 KMDDPTVNWSNERYEECKEKLVPFLKKVGFNPKKDIHFMPCSGLTGANL---KEQSDFCP
:::. :::..::..: :: :::..::. ..:. :.: :::.: :: ...:..
NP_001 KMDQ--VNWQQERFQEITGKLGHFLKQAGFK-ESDVGFIPTSGLSGENLITRSQSSELTK
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE2 WYIGLPFIPYLDNLPNFNRSVDGPIRLPIVDKYKDMGT--VVLGKLESGSICKGQQLVMM
:: :: .. .:.. .::.: :.:: . : .::.:. . ::.:.: : :..:. :
NP_001 WYKGLCLLEQIDSFKPPQRSIDKPFRLCVSDVFKDQGSGFCITGKIEAGYIQTGDRLLAM
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE2 PNKHNVEVLGILSDDVETDTVAPGENLKIRLKGIEEEEILPGFILCDPNNLCHSGRTFDA
: ... : :: : .: .: :..... : :.. .: : :.: :. .. : :
NP_001 PPNETCTVKGITLHDEPVDWAAAGDHVSLTLVGMDIIKINVGCIFCGPKVPIKACTRFRA
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE2 QIVIIEHKSIICPGYNAVLHIHTCIEEVEITALICLVDKKSGEKSKTRPRFVKQDQVCIA
.:.:.. . : :. ..:: .: : . : :: ...:..:: .: .:.:. . : ..
NP_001 RILIFNIEIPITKGFPVLLHYQTVSEPAVIKRLISVLNKSTGEVTKKKPKFLTKGQNALV
550 560 570 580 590 600
600 610 620 630
pF1KE2 RLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD
.:.: : :: .::: ..::: :: :.::: : : ..
NP_001 ELQTQRPIALELYKDFKELGRFMLRYGGSTIAAGVVTEIKE
610 620 630 640
>>NP_006611 (OMIM: 612450) HBS1-like protein isoform 1 [ (684 aa)
initn: 926 init1: 637 opt: 1162 Z-score: 881.5 bits: 173.4 E(85289): 2.3e-42
Smith-Waterman score: 1170; 37.3% identity (66.5% similar) in 549 aa overlap (107-629:139-682)
80 90 100 110 120 130
pF1KE2 VHAAEFVPSFLRCPAAPPPPAGGAANNHGAGSGAGGRAAPVESSQEEQSLCEG------S
:. : :. . ..:. :. . :
NP_006 KFDVQKALSGVLEQDRVQSLKDKNEATVSTGKIAKGKPVDSQTSRSESEIVPKVAKMTVS
110 120 130 140 150 160
140 150 160 170 180
pF1KE2 NSAVSMELSEPIV---ENGETEMSPEESWEHKEEISEAEPGGGSLGDGRPPEESAHEMME
.. .: . : : :::.. .:... .. :. .. . .. ::. . :
NP_006 GKKQTMGFEVPGVSSEENGHSFHTPQKGPPIEDAIASSDVLETASKSANPPHTI--QASE
170 180 190 200 210 220
190 200 210 220 230
pF1KE2 EEEEIPKP--------KSVVAPPGAPK----KEHVNVVFIGHVDAGKSTIGGQIMYLTGM
:. : : ... . : :. .:.: ::::::::::. :...:: :
NP_006 EQSSTPAPVKKSGKLRQQIDVKAELEKRQGGKQLLNLVVIGHVDAGKSTLMGHMLYLLGN
230 240 250 260 270 280
240 250 260 270 280 290
pF1KE2 VDKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAP
..:::..:::.:.:. .. .. .:.:: . :::..: :..:: . ::: : .:..:::
NP_006 INKRTMHKYEQESKKAGKASFAYAWVLDETGEERERGVTMDVGMTKFETTTKVITLMDAP
290 300 310 320 330 340
300 310 320 330 340 350
pF1KE2 GHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLIN
:::.:.:::: ::.:::.::::..: .::::.::: :::::::..:... :: .: : .:
NP_006 GHKDFIPNMITGAAQADVAVLVVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLAVAVN
350 360 370 380 390 400
360 370 380 390 400 410
pF1KE2 KMDDPTVNWSNERYEECKEKLVPFLKKVGFNPKKDIHFMPCSGLTGANL---KEQSDFCP
:::. :::..::..: :: :::..::. ..:. :.: :::.: :: ...:..
NP_006 KMDQ--VNWQQERFQEITGKLGHFLKQAGFK-ESDVGFIPTSGLSGENLITRSQSSELTK
410 420 430 440 450 460
420 430 440 450 460 470
pF1KE2 WYIGLPFIPYLDNLPNFNRSVDGPIRLPIVDKYKDMGT--VVLGKLESGSICKGQQLVMM
:: :: .. .:.. .::.: :.:: . : .::.:. . ::.:.: : :..:. :
NP_006 WYKGLCLLEQIDSFKPPQRSIDKPFRLCVSDVFKDQGSGFCITGKIEAGYIQTGDRLLAM
470 480 490 500 510 520
480 490 500 510 520 530
pF1KE2 PNKHNVEVLGILSDDVETDTVAPGENLKIRLKGIEEEEILPGFILCDPNNLCHSGRTFDA
: ... : :: : .: .: :..... : :.. .: : :.: :. .. : :
NP_006 PPNETCTVKGITLHDEPVDWAAAGDHVSLTLVGMDIIKINVGCIFCGPKVPIKACTRFRA
530 540 550 560 570 580
540 550 560 570 580 590
pF1KE2 QIVIIEHKSIICPGYNAVLHIHTCIEEVEITALICLVDKKSGEKSKTRPRFVKQDQVCIA
.:.:.. . : :. ..:: .: : . : :: ...:..:: .: .:.:. . : ..
NP_006 RILIFNIEIPITKGFPVLLHYQTVSEPAVIKRLISVLNKSTGEVTKKKPKFLTKGQNALV
590 600 610 620 630 640
600 610 620 630
pF1KE2 RLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD
.:.: : :: .::: ..::: :: :.::: : : ..
NP_006 ELQTQRPIALELYKDFKELGRFMLRYGGSTIAAGVVTEIKE
650 660 670 680
>>XP_011533816 (OMIM: 130590) PREDICTED: elongation fact (462 aa)
initn: 909 init1: 642 opt: 707 Z-score: 542.9 bits: 110.2 E(85289): 1.7e-23
Smith-Waterman score: 1046; 38.4% identity (66.7% similar) in 445 aa overlap (206-633:4-444)
180 190 200 210 220 230
pF1KE2 RPPEESAHEMMEEEEEIPKPKSVVAPPGAPKKEHVNVVFIGHVDAGKSTIGGQIMYLTGM
.: :.:.: :::::.:::: :...: :
XP_011 MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGG
10 20 30
240 250 260 270 280 290
pF1KE2 VDKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAP
.::::.::.:.:: : .. .. .:.:: . ::..: :.... ::: : . ::.:::
XP_011 IDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETSKYYVTIIDAP
40 50 60 70 80 90
300 310 320 330 340 350
pF1KE2 GHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLIN
::..:. ::: :.:::: :::...: ::::.:. :.:::::::.:: : :::.::: .:
XP_011 GHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVN
100 110 120 130 140 150
360 370 380 390 400 410
pF1KE2 KMDDPTVNWSNERYEECKEKLVPFLKKVGFNPKKDIHFMPCSGLTGANLKEQSDFCPWYI
:::. .:..:::: ... ..::.:.:: . :.: :: .: :. : : ::.
XP_011 KMDSTEPPYSQKRYEEIVKEVSTYIKKIGYNPDT-VAFVPISGWNGDNMLEPSANMPWFK
160 170 180 190 200 210
420 430 440 450 460
pF1KE2 G------------LPFIPYLDNLPNFNRSVDGPIRLPIVDKYK--DMGTVVLGKLESGSI
: .. :: . .: .: :.:::. : :: .::: .:..:.: .
XP_011 GWKVTRKDGNASGTTLLEALDCILPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVL
220 230 240 250 260 270
470 480 490 500 510 520
pF1KE2 CKGQQLVMMPNKHNVEVLGILSDDVETDTVAPGENLKIRLKGIEEEEILPGFILCDPNN-
:. ... : . ..:: .. . . ::.:. . .:.. ... : . : .:
XP_011 KPGMVVTFAPVNVTTEVKSVEMHHEALSEALPGDNVGFNVKNVSVKDVRRGNVAGDSKND
280 290 300 310 320 330
530 540 550 560 570
pF1KE2 --LCHSGRTFDAQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALICLVDKKSGEKSKTR
. .: : ::..:..: . : :: :: :: ... : .:..::.: .
XP_011 PPMEAAG--FTAQVIILNHPGQISAGYAPVLDCHTAHIACKFAELKEKIDRRSGKKLEDG
340 350 360 370 380 390
580 590 600 610 620 630
pF1KE2 PRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD
:.:.:. .. :. . . .:.:.:.:.: .:::..:: .:.:.: :.: : .:
XP_011 PKFLKSGDAAIVDMVPGKPMCVESFSDYPPLGRFAVRDMRQTVAVG-VIKAVDKKAAGAG
400 410 420 430 440
XP_011 KVTKSAQKAQKAK
450 460
>>NP_001393 (OMIM: 130590) elongation factor 1-alpha 1 [ (462 aa)
initn: 909 init1: 642 opt: 707 Z-score: 542.9 bits: 110.2 E(85289): 1.7e-23
Smith-Waterman score: 1046; 38.4% identity (66.7% similar) in 445 aa overlap (206-633:4-444)
180 190 200 210 220 230
pF1KE2 RPPEESAHEMMEEEEEIPKPKSVVAPPGAPKKEHVNVVFIGHVDAGKSTIGGQIMYLTGM
.: :.:.: :::::.:::: :...: :
NP_001 MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGG
10 20 30
240 250 260 270 280 290
pF1KE2 VDKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAP
.::::.::.:.:: : .. .. .:.:: . ::..: :.... ::: : . ::.:::
NP_001 IDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETSKYYVTIIDAP
40 50 60 70 80 90
300 310 320 330 340 350
pF1KE2 GHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLIN
::..:. ::: :.:::: :::...: ::::.:. :.:::::::.:: : :::.::: .:
NP_001 GHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVN
100 110 120 130 140 150
360 370 380 390 400 410
pF1KE2 KMDDPTVNWSNERYEECKEKLVPFLKKVGFNPKKDIHFMPCSGLTGANLKEQSDFCPWYI
:::. .:..:::: ... ..::.:.:: . :.: :: .: :. : : ::.
NP_001 KMDSTEPPYSQKRYEEIVKEVSTYIKKIGYNPDT-VAFVPISGWNGDNMLEPSANMPWFK
160 170 180 190 200 210
420 430 440 450 460
pF1KE2 G------------LPFIPYLDNLPNFNRSVDGPIRLPIVDKYK--DMGTVVLGKLESGSI
: .. :: . .: .: :.:::. : :: .::: .:..:.: .
NP_001 GWKVTRKDGNASGTTLLEALDCILPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVL
220 230 240 250 260 270
470 480 490 500 510 520
pF1KE2 CKGQQLVMMPNKHNVEVLGILSDDVETDTVAPGENLKIRLKGIEEEEILPGFILCDPNN-
:. ... : . ..:: .. . . ::.:. . .:.. ... : . : .:
NP_001 KPGMVVTFAPVNVTTEVKSVEMHHEALSEALPGDNVGFNVKNVSVKDVRRGNVAGDSKND
280 290 300 310 320 330
530 540 550 560 570
pF1KE2 --LCHSGRTFDAQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALICLVDKKSGEKSKTR
. .: : ::..:..: . : :: :: :: ... : .:..::.: .
NP_001 PPMEAAG--FTAQVIILNHPGQISAGYAPVLDCHTAHIACKFAELKEKIDRRSGKKLEDG
340 350 360 370 380 390
580 590 600 610 620 630
pF1KE2 PRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD
:.:.:. .. :. . . .:.:.:.:.: .:::..:: .:.:.: :.: : .:
NP_001 PKFLKSGDAAIVDMVPGKPMCVESFSDYPPLGRFAVRDMRQTVAVG-VIKAVDKKAAGAG
400 410 420 430 440
NP_001 KVTKSAQKAQKAK
450 460
>>NP_001949 (OMIM: 602959,616393,616409) elongation fact (463 aa)
initn: 886 init1: 640 opt: 704 Z-score: 540.6 bits: 109.8 E(85289): 2.2e-23
Smith-Waterman score: 1020; 37.2% identity (67.5% similar) in 443 aa overlap (206-633:4-444)
180 190 200 210 220 230
pF1KE2 RPPEESAHEMMEEEEEIPKPKSVVAPPGAPKKEHVNVVFIGHVDAGKSTIGGQIMYLTGM
.: :.:.: :::::.:::: :...: :
NP_001 MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGG
10 20 30
240 250 260 270 280 290
pF1KE2 VDKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAP
.::::.::.:.:: : .. .. .:.:: . ::..: :.... ::: : ..::.:::
NP_001 IDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETTKYYITIIDAP
40 50 60 70 80 90
300 310 320 330 340 350
pF1KE2 GHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLIN
::..:. ::: :.:::: :::...: ::::.:. :.:::::::.:: : :::.::: .:
NP_001 GHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVN
100 110 120 130 140 150
360 370 380 390 400 410
pF1KE2 KMDDPTVNWSNERYEECKEKLVPFLKKVGFNPKKDIHFMPCSGLTGANLKEQSDFCPWYI
:::. .:..::.: ... ..::.:.:: . :.: :: : :. : : ::.
NP_001 KMDSTEPAYSEKRYDEIVKEVSAYIKKIGYNPAT-VPFVPISGWHGDNMLEPSPNMPWFK
160 170 180 190 200 210
420 430 440 450 460
pF1KE2 G------------LPFIPYLDNLPNFNRSVDGPIRLPIVDKYK--DMGTVVLGKLESGSI
: . .. ::.. .: .: :.:::. : :: .::: .:..:.: .
NP_001 GWKVERKEGNASGVSLLEALDTILPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGIL
220 230 240 250 260 270
470 480 490 500 510 520
pF1KE2 CKGQQLVMMPNKHNVEVLGILSDDVETDTVAPGENLKIRLKGIEEEEILPGFILCDP-NN
:. ... : . ..:: .. . . ::.:. . .:.. ..: : . : ..
NP_001 RPGMVVTFAPVNITTEVKSVEMHHEALSEALPGDNVGFNVKNVSVKDIRRGNVCGDSKSD
280 290 300 310 320 330
530 540 550 560 570 580
pF1KE2 LCHSGRTFDAQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALICLVDKKSGEKSKTRPR
. . : .:..:..: . : ::. :. :: ... : .:..::.: . :.
NP_001 PPQEAAQFTSQVIILNHPGQISAGYSPVIDCHTAHIACKFAELKEKIDRRSGKKLEDNPK
340 350 360 370 380 390
590 600 610 620 630
pF1KE2 FVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD
.:. .. :... . .:.:.:...: .:::..:: .:.:.: :.: : .:
NP_001 SLKSGDAAIVEMVPGKPMCVESFSQYPPLGRFAVRDMRQTVAVG-VIKNVEKKSGGAGKV
400 410 420 430 440 450
NP_001 TKSAQKAQKAGK
460
>>NP_003312 (OMIM: 602389,610678) elongation factor Tu, (455 aa)
initn: 407 init1: 148 opt: 272 Z-score: 217.2 bits: 49.9 E(85289): 2.3e-05
Smith-Waterman score: 401; 27.8% identity (54.7% similar) in 338 aa overlap (207-535:58-362)
180 190 200 210 220 230
pF1KE2 PPEESAHEMMEEEEEIPKPKSVVAPPGAPKKEHVNVVFIGHVDAGKSTIGGQIMYLTGMV
: :::: ::::: ::.:. . : . .
NP_003 QGLLRLLKAPALPLLCRGLAVEAKKTYVRDKPHVNVGTIGHVDHGKTTLTAAITKILAEG
30 40 50 60 70 80
240 250 260 270 280 290
pF1KE2 DKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPG
..:::. .:. ::: .: :...... . : .:.. : ::
NP_003 GGAKFKKYEE---------------IDNAPEERARGITINAAHVEYSTAARHYAHTDCPG
90 100 110 120 130
300 310 320 330 340 350
pF1KE2 HKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINK
: ..: ::: :.. : .::..: : . ::::: .::. ::.:..: .::
NP_003 HADYVKNMITGTAPLDGCILVVAANDGPMP-------QTREHLLLARQIGVEHVVVYVNK
140 150 160 170 180
360 370 380 390 400 410
pF1KE2 MDDPTVNWSNERYEECKEKLVPFLKKVGFNPKKDIHFMPCSGLTGANLKEQSDFCPWYIG
: . ..: : . .. .: . :.. .. : ..:. : : .:
NP_003 AD---AVQDSEMVELVELEIRELLTEFGYKGEET----PV--IVGSALCALEGRDP-ELG
190 200 210 220 230
420 430 440 450 460
pF1KE2 LPFIPYLDN-----LPNFNRSVDGPIRLPIVDKYK--DMGTVVLGKLESGSICKGQQLVM
: . : . .: :... :. ::. :. :::: : :: : . ::.. .
NP_003 LKSVQKLLDAVDTYIPVPARDLEKPFLLPVEAVYSVPGRGTVVTGTLERGILKKGDECEL
240 250 260 270 280 290
470 480 490 500 510 520
pF1KE2 MPNKHNVE--VLGILSDDVETDTVAPGENLKIRLKGIEEEEILPGFILCDPNNLCHSGRT
. ...:.. : :: . . :.:: ..:...:.. :... :... . .
NP_003 LGHSKNIRTVVTGIEMFHKSLERAEAGDNLGALVRGLKREDLRRGLVMVKPGSI-KPHQK
300 310 320 330 340 350
530 540 550 560 570 580
pF1KE2 FDAQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALICLVDKKSGEKSKTRPRFVKQDQV
.::. :.
NP_003 VEAQVYILSKEEGGRHKPFVSHFMPVMFSLTWDMACRIILPPEKELAMPGEDLKFNLILR
360 370 380 390 400 410
634 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 21:40:49 2016 done: Sun Nov 6 21:40:51 2016
Total Scan time: 12.750 Total Display time: 0.130
Function used was FASTA [36.3.4 Apr, 2011]