Result of FASTA (omim) for
pFN21AE2035
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2035, 629 aa
1>>>pF1KE2035 629 - 629 aa - 629 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6643+/-0.000448; mu= 17.9708+/- 0.028
mean_var=85.4899+/-17.371, 0's: 0 Z-trim(110.1): 103 B-trim: 0 in 0/54
Lambda= 0.138713
statistics sampled from 18279 (18383) to 18279 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.573), E-opt: 0.2 (0.216), width: 16
Scan time: 10.440
The best scores are: opt bits E(85289)
XP_011539093 (OMIM: 605606,607562,612261) PREDICTE ( 629) 4195 850.2 0
NP_653302 (OMIM: 605606,607562,612261) interleukin ( 629) 4195 850.2 0
XP_011539092 (OMIM: 605606,607562,612261) PREDICTE ( 629) 4195 850.2 0
XP_005270573 (OMIM: 605606,607562,612261) PREDICTE ( 375) 2465 503.9 4.2e-142
XP_016856693 (OMIM: 601642) PREDICTED: interleukin ( 498) 307 72.1 5.3e-12
NP_001245145 (OMIM: 601642) interleukin-12 recepto ( 635) 307 72.2 6.4e-12
NP_001306162 (OMIM: 601642) interleukin-12 recepto ( 659) 307 72.2 6.6e-12
XP_016856692 (OMIM: 601642) PREDICTED: interleukin ( 659) 307 72.2 6.6e-12
NP_001245143 (OMIM: 601642) interleukin-12 recepto ( 659) 307 72.2 6.6e-12
XP_016856691 (OMIM: 601642) PREDICTED: interleukin ( 700) 307 72.2 6.9e-12
NP_001245144 (OMIM: 601642) interleukin-12 recepto ( 776) 307 72.2 7.5e-12
XP_006710680 (OMIM: 601642) PREDICTED: interleukin ( 776) 307 72.2 7.5e-12
XP_011539686 (OMIM: 601642) PREDICTED: interleukin ( 809) 307 72.3 7.7e-12
XP_005270885 (OMIM: 601642) PREDICTED: interleukin ( 862) 307 72.3 8.1e-12
XP_005270882 (OMIM: 601642) PREDICTED: interleukin ( 862) 307 72.3 8.1e-12
XP_011539685 (OMIM: 601642) PREDICTED: interleukin ( 862) 307 72.3 8.1e-12
XP_005270884 (OMIM: 601642) PREDICTED: interleukin ( 862) 307 72.3 8.1e-12
NP_001550 (OMIM: 601642) interleukin-12 receptor s ( 862) 307 72.3 8.1e-12
NP_786943 (OMIM: 600694) interleukin-6 receptor su ( 329) 287 68.0 6.1e-11
NP_001177910 (OMIM: 600694) interleukin-6 receptor ( 857) 288 68.5 1.1e-10
NP_002175 (OMIM: 600694) interleukin-6 receptor su ( 918) 288 68.5 1.2e-10
XP_011526726 (OMIM: 272430,604237) PREDICTED: cyto ( 404) 225 55.6 3.9e-07
XP_011526725 (OMIM: 272430,604237) PREDICTED: cyto ( 419) 225 55.6 4e-07
NP_004741 (OMIM: 272430,604237) cytokine receptor- ( 422) 225 55.6 4e-07
XP_011526724 (OMIM: 272430,604237) PREDICTED: cyto ( 423) 225 55.6 4e-07
XP_011512342 (OMIM: 151443,601559) PREDICTED: leuk (1097) 223 55.5 1.1e-06
NP_002301 (OMIM: 151443,601559) leukemia inhibitor (1097) 223 55.5 1.1e-06
XP_016864952 (OMIM: 151443,601559) PREDICTED: leuk (1097) 223 55.5 1.1e-06
XP_011512344 (OMIM: 151443,601559) PREDICTED: leuk (1097) 223 55.5 1.1e-06
NP_001121143 (OMIM: 151443,601559) leukemia inhibi (1097) 223 55.5 1.1e-06
XP_016864951 (OMIM: 151443,601559) PREDICTED: leuk (1115) 223 55.5 1.1e-06
NP_001191247 (OMIM: 176761,615554,615555) prolacti ( 268) 155 41.5 0.0046
NP_001191246 (OMIM: 176761,615554,615555) prolacti ( 288) 154 41.3 0.0056
XP_016865135 (OMIM: 176761,615554,615555) PREDICTE ( 309) 154 41.3 0.006
NP_001191244 (OMIM: 176761,615554,615555) prolacti ( 349) 154 41.4 0.0066
NP_001191245 (OMIM: 176761,615554,615555) prolacti ( 376) 154 41.4 0.007
XP_016869752 (OMIM: 118946) PREDICTED: ciliary neu ( 372) 152 41.0 0.0091
NP_001193940 (OMIM: 118946) ciliary neurotrophic f ( 372) 152 41.0 0.0091
NP_001833 (OMIM: 118946) ciliary neurotrophic fact ( 372) 152 41.0 0.0091
XP_016869754 (OMIM: 118946) PREDICTED: ciliary neu ( 372) 152 41.0 0.0091
XP_016869753 (OMIM: 118946) PREDICTED: ciliary neu ( 372) 152 41.0 0.0091
NP_671693 (OMIM: 118946) ciliary neurotrophic fact ( 372) 152 41.0 0.0091
XP_016865134 (OMIM: 176761,615554,615555) PREDICTE ( 551) 154 41.5 0.0094
>>XP_011539093 (OMIM: 605606,607562,612261) PREDICTED: i (629 aa)
initn: 4195 init1: 4195 opt: 4195 Z-score: 4540.1 bits: 850.2 E(85289): 0
Smith-Waterman score: 4195; 99.8% identity (99.8% similar) in 629 aa overlap (1-629:1-629)
10 20 30 40 50 60
pF1KE2 MNQVTIQWDAVIALYILFSWCHGGITNINCSGHIWVEPATIFKMGMNISIYCQAAIKNCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNQVTIQWDAVIALYILFSWCHGGITNINCSGHIWVEPATIFKMGMNISIYCQAAIKNCQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PRKLHFYKNGIKERFQITRINKTTARLWYKNFLEPHASMYCTAECPKHFQETLICGKDIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRKLHFYKNGIKERFQITRINKTTARLWYKNFLEPHASMYCTAECPKHFQETLICGKDIS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 SGYPPDIPDEVTCVIYEYSGNMTCTWNAGKLTYIDTKYVVHVKSLETEEEQQYLTSSYIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGYPPDIPDEVTCVIYEYSGNMTCTWNAGKLTYIDTKYVVHVKSLETEEEQQYLTSSYIN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 ISTDSLQGGKKYLVWVQAANALGMEESKQLQIHLDDIVIPSAAVISRAETINATVPKTII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISTDSLQGGKKYLVWVQAANALGMEESKQLQIHLDDIVIPSAAVISRAETINATVPKTII
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 YWDSQTTIEKVSCEMRYKATTNQTWNVKEFDTNFTYVQQSEFYLEPNIKYVFQVRCQETG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YWDSQTTIEKVSCEMRYKATTNQTWNVKEFDTNFTYVQQSEFYLEPNIKYVFQVRCQETG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 KRYWQPWSSPFFHKTPETVPQVTSKAFQHDTWNSGLTVASISTGHLTSDNRGDIGLLLGM
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRYWQPWSSLFFHKTPETVPQVTSKAFQHDTWNSGLTVASISTGHLTSDNRGDIGLLLGM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 IVFAVMLSILSLIGIFNRSFRTGIKRRILLLIPKWLYEDIPNMKNSNVVKMLQENSELMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVFAVMLSILSLIGIFNRSFRTGIKRRILLLIPKWLYEDIPNMKNSNVVKMLQENSELMN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 NNSSEQVLYVDPMITEIKEIFIPEHKPTDYKKENTGPLETRDYPQNSLFDNTTVVYIPDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NNSSEQVLYVDPMITEIKEIFIPEHKPTDYKKENTGPLETRDYPQNSLFDNTTVVYIPDL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 NTGYKPQISNFLPEGSHLSNNNEITSLTLKPPVDSLDSGNNPRLQKHPNFAFSVSSVNSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTGYKPQISNFLPEGSHLSNNNEITSLTLKPPVDSLDSGNNPRLQKHPNFAFSVSSVNSL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 SNTIFLGELSLILNQGECSSPDIQNSVEEETTMLLENDSPSETIPEQTLLPDEFVSCLGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNTIFLGELSLILNQGECSSPDIQNSVEEETTMLLENDSPSETIPEQTLLPDEFVSCLGI
550 560 570 580 590 600
610 620
pF1KE2 VNEELPSINTYFPQNILESHFNRISLLEK
:::::::::::::::::::::::::::::
XP_011 VNEELPSINTYFPQNILESHFNRISLLEK
610 620
>>NP_653302 (OMIM: 605606,607562,612261) interleukin-23 (629 aa)
initn: 4195 init1: 4195 opt: 4195 Z-score: 4540.1 bits: 850.2 E(85289): 0
Smith-Waterman score: 4195; 99.8% identity (99.8% similar) in 629 aa overlap (1-629:1-629)
10 20 30 40 50 60
pF1KE2 MNQVTIQWDAVIALYILFSWCHGGITNINCSGHIWVEPATIFKMGMNISIYCQAAIKNCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 MNQVTIQWDAVIALYILFSWCHGGITNINCSGHIWVEPATIFKMGMNISIYCQAAIKNCQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PRKLHFYKNGIKERFQITRINKTTARLWYKNFLEPHASMYCTAECPKHFQETLICGKDIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 PRKLHFYKNGIKERFQITRINKTTARLWYKNFLEPHASMYCTAECPKHFQETLICGKDIS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 SGYPPDIPDEVTCVIYEYSGNMTCTWNAGKLTYIDTKYVVHVKSLETEEEQQYLTSSYIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 SGYPPDIPDEVTCVIYEYSGNMTCTWNAGKLTYIDTKYVVHVKSLETEEEQQYLTSSYIN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 ISTDSLQGGKKYLVWVQAANALGMEESKQLQIHLDDIVIPSAAVISRAETINATVPKTII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 ISTDSLQGGKKYLVWVQAANALGMEESKQLQIHLDDIVIPSAAVISRAETINATVPKTII
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 YWDSQTTIEKVSCEMRYKATTNQTWNVKEFDTNFTYVQQSEFYLEPNIKYVFQVRCQETG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 YWDSQTTIEKVSCEMRYKATTNQTWNVKEFDTNFTYVQQSEFYLEPNIKYVFQVRCQETG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 KRYWQPWSSPFFHKTPETVPQVTSKAFQHDTWNSGLTVASISTGHLTSDNRGDIGLLLGM
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 KRYWQPWSSLFFHKTPETVPQVTSKAFQHDTWNSGLTVASISTGHLTSDNRGDIGLLLGM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 IVFAVMLSILSLIGIFNRSFRTGIKRRILLLIPKWLYEDIPNMKNSNVVKMLQENSELMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 IVFAVMLSILSLIGIFNRSFRTGIKRRILLLIPKWLYEDIPNMKNSNVVKMLQENSELMN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 NNSSEQVLYVDPMITEIKEIFIPEHKPTDYKKENTGPLETRDYPQNSLFDNTTVVYIPDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 NNSSEQVLYVDPMITEIKEIFIPEHKPTDYKKENTGPLETRDYPQNSLFDNTTVVYIPDL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 NTGYKPQISNFLPEGSHLSNNNEITSLTLKPPVDSLDSGNNPRLQKHPNFAFSVSSVNSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 NTGYKPQISNFLPEGSHLSNNNEITSLTLKPPVDSLDSGNNPRLQKHPNFAFSVSSVNSL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 SNTIFLGELSLILNQGECSSPDIQNSVEEETTMLLENDSPSETIPEQTLLPDEFVSCLGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 SNTIFLGELSLILNQGECSSPDIQNSVEEETTMLLENDSPSETIPEQTLLPDEFVSCLGI
550 560 570 580 590 600
610 620
pF1KE2 VNEELPSINTYFPQNILESHFNRISLLEK
:::::::::::::::::::::::::::::
NP_653 VNEELPSINTYFPQNILESHFNRISLLEK
610 620
>>XP_011539092 (OMIM: 605606,607562,612261) PREDICTED: i (629 aa)
initn: 4195 init1: 4195 opt: 4195 Z-score: 4540.1 bits: 850.2 E(85289): 0
Smith-Waterman score: 4195; 99.8% identity (99.8% similar) in 629 aa overlap (1-629:1-629)
10 20 30 40 50 60
pF1KE2 MNQVTIQWDAVIALYILFSWCHGGITNINCSGHIWVEPATIFKMGMNISIYCQAAIKNCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNQVTIQWDAVIALYILFSWCHGGITNINCSGHIWVEPATIFKMGMNISIYCQAAIKNCQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PRKLHFYKNGIKERFQITRINKTTARLWYKNFLEPHASMYCTAECPKHFQETLICGKDIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRKLHFYKNGIKERFQITRINKTTARLWYKNFLEPHASMYCTAECPKHFQETLICGKDIS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 SGYPPDIPDEVTCVIYEYSGNMTCTWNAGKLTYIDTKYVVHVKSLETEEEQQYLTSSYIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGYPPDIPDEVTCVIYEYSGNMTCTWNAGKLTYIDTKYVVHVKSLETEEEQQYLTSSYIN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 ISTDSLQGGKKYLVWVQAANALGMEESKQLQIHLDDIVIPSAAVISRAETINATVPKTII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISTDSLQGGKKYLVWVQAANALGMEESKQLQIHLDDIVIPSAAVISRAETINATVPKTII
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 YWDSQTTIEKVSCEMRYKATTNQTWNVKEFDTNFTYVQQSEFYLEPNIKYVFQVRCQETG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YWDSQTTIEKVSCEMRYKATTNQTWNVKEFDTNFTYVQQSEFYLEPNIKYVFQVRCQETG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 KRYWQPWSSPFFHKTPETVPQVTSKAFQHDTWNSGLTVASISTGHLTSDNRGDIGLLLGM
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRYWQPWSSLFFHKTPETVPQVTSKAFQHDTWNSGLTVASISTGHLTSDNRGDIGLLLGM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 IVFAVMLSILSLIGIFNRSFRTGIKRRILLLIPKWLYEDIPNMKNSNVVKMLQENSELMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVFAVMLSILSLIGIFNRSFRTGIKRRILLLIPKWLYEDIPNMKNSNVVKMLQENSELMN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 NNSSEQVLYVDPMITEIKEIFIPEHKPTDYKKENTGPLETRDYPQNSLFDNTTVVYIPDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NNSSEQVLYVDPMITEIKEIFIPEHKPTDYKKENTGPLETRDYPQNSLFDNTTVVYIPDL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 NTGYKPQISNFLPEGSHLSNNNEITSLTLKPPVDSLDSGNNPRLQKHPNFAFSVSSVNSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTGYKPQISNFLPEGSHLSNNNEITSLTLKPPVDSLDSGNNPRLQKHPNFAFSVSSVNSL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 SNTIFLGELSLILNQGECSSPDIQNSVEEETTMLLENDSPSETIPEQTLLPDEFVSCLGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNTIFLGELSLILNQGECSSPDIQNSVEEETTMLLENDSPSETIPEQTLLPDEFVSCLGI
550 560 570 580 590 600
610 620
pF1KE2 VNEELPSINTYFPQNILESHFNRISLLEK
:::::::::::::::::::::::::::::
XP_011 VNEELPSINTYFPQNILESHFNRISLLEK
610 620
>>XP_005270573 (OMIM: 605606,607562,612261) PREDICTED: i (375 aa)
initn: 2465 init1: 2465 opt: 2465 Z-score: 2672.2 bits: 503.9 E(85289): 4.2e-142
Smith-Waterman score: 2465; 99.7% identity (99.7% similar) in 375 aa overlap (255-629:1-375)
230 240 250 260 270 280
pF1KE2 ISRAETINATVPKTIIYWDSQTTIEKVSCEMRYKATTNQTWNVKEFDTNFTYVQQSEFYL
::::::::::::::::::::::::::::::
XP_005 MRYKATTNQTWNVKEFDTNFTYVQQSEFYL
10 20 30
290 300 310 320 330 340
pF1KE2 EPNIKYVFQVRCQETGKRYWQPWSSPFFHKTPETVPQVTSKAFQHDTWNSGLTVASISTG
::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
XP_005 EPNIKYVFQVRCQETGKRYWQPWSSLFFHKTPETVPQVTSKAFQHDTWNSGLTVASISTG
40 50 60 70 80 90
350 360 370 380 390 400
pF1KE2 HLTSDNRGDIGLLLGMIVFAVMLSILSLIGIFNRSFRTGIKRRILLLIPKWLYEDIPNMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HLTSDNRGDIGLLLGMIVFAVMLSILSLIGIFNRSFRTGIKRRILLLIPKWLYEDIPNMK
100 110 120 130 140 150
410 420 430 440 450 460
pF1KE2 NSNVVKMLQENSELMNNNSSEQVLYVDPMITEIKEIFIPEHKPTDYKKENTGPLETRDYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSNVVKMLQENSELMNNNSSEQVLYVDPMITEIKEIFIPEHKPTDYKKENTGPLETRDYP
160 170 180 190 200 210
470 480 490 500 510 520
pF1KE2 QNSLFDNTTVVYIPDLNTGYKPQISNFLPEGSHLSNNNEITSLTLKPPVDSLDSGNNPRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QNSLFDNTTVVYIPDLNTGYKPQISNFLPEGSHLSNNNEITSLTLKPPVDSLDSGNNPRL
220 230 240 250 260 270
530 540 550 560 570 580
pF1KE2 QKHPNFAFSVSSVNSLSNTIFLGELSLILNQGECSSPDIQNSVEEETTMLLENDSPSETI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QKHPNFAFSVSSVNSLSNTIFLGELSLILNQGECSSPDIQNSVEEETTMLLENDSPSETI
280 290 300 310 320 330
590 600 610 620
pF1KE2 PEQTLLPDEFVSCLGIVNEELPSINTYFPQNILESHFNRISLLEK
:::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEQTLLPDEFVSCLGIVNEELPSINTYFPQNILESHFNRISLLEK
340 350 360 370
>>XP_016856693 (OMIM: 601642) PREDICTED: interleukin-12 (498 aa)
initn: 226 init1: 132 opt: 307 Z-score: 336.5 bits: 72.1 E(85289): 5.3e-12
Smith-Waterman score: 307; 23.5% identity (56.0% similar) in 327 aa overlap (12-320:10-321)
10 20 30 40 50
pF1KE2 MNQVTIQWDAVIALYILFSWCHGGITNINCS-GHIWVEPATIFKMGMNISIYCQAAIKNC
.:......: :. : . :.:. .. .: ...: : .
XP_016 MAHTFRGCSLAFMFIITWLLIKAKIDACKRGDVTVKPSHVILLGSTVNITC-----SL
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 QPRK--LHFYKNG--IKERFQITRINKTTARLWYKNF--LEPHASMY-CTAECPKHFQET
.::. .:. . . : .:. ::: .. .. : .... : : . .:
XP_016 KPRQGCFHYSRRNKLILYKFD-RRINFHHGHSLNSQVTGLPLGTTLFVCKLACINS-DEI
60 70 80 90 100 110
120 130 140 150 160
pF1KE2 LICGKDISSGYPPDIPDEVTCVIYEYSGNMTCTWNAGKLTYIDTKYVVHV---KSLETEE
::: .: : :. :....:. .:...:::. :. :.. :.:.... :.: ..
XP_016 QICGAEIFVGVAPEQPQNLSCIQKGEQGTVACTWERGRDTHLYTEYTLQLSGPKNLTWQK
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE2 EQQYLTSSY----INISTDSLQGGKKYLVWVQAANALGMEESKQLQIHLDDIVIPSAAVI
. . . .: ::.. .: .. .. . : :.:.:: : . . ::: :
XP_016 QCKDIYCDYLDFGINLTPESPES--NFTAKVTAVNSLGSSSSLPSTFTFLDIVRPLPPWD
180 190 200 210 220
230 240 250 260 270 280
pF1KE2 SRAETINATVPKTIIYWDSQTTIEKVSCEMRYKATTNQTWNVKEFDTNFTYVQ--QSEFY
: . .:.: . .:: .. . . ..::. .... ::. .: : .. .. .
XP_016 IRIKFQKASVSRCTLYWRDEGLV--LLNRLRYRPSNSRLWNM----VNVTKAKGRHDLLD
230 240 250 260 270 280
290 300 310 320 330 340
pF1KE2 LEPNIKYVFQVRCQ-ETGKRYWQPWSSPFFHKTPETVPQVTSKAFQHDTWNSGLTVASIS
:.: .: ::. . . : :. :: . .::: :
XP_016 LKPFTEYEFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHIDYSRQQISL
290 300 310 320 330 340
350 360 370 380 390 400
pF1KE2 TGHLTSDNRGDIGLLLGMIVFAVMLSILSLIGIFNRSFRTGIKRRILLLIPKWLYEDIPN
XP_016 FWKNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSK
350 360 370 380 390 400
>>NP_001245145 (OMIM: 601642) interleukin-12 receptor su (635 aa)
initn: 226 init1: 132 opt: 307 Z-score: 335.0 bits: 72.2 E(85289): 6.4e-12
Smith-Waterman score: 307; 23.5% identity (56.0% similar) in 327 aa overlap (12-320:10-321)
10 20 30 40 50
pF1KE2 MNQVTIQWDAVIALYILFSWCHGGITNINCS-GHIWVEPATIFKMGMNISIYCQAAIKNC
.:......: :. : . :.:. .. .: ...: : .
NP_001 MAHTFRGCSLAFMFIITWLLIKAKIDACKRGDVTVKPSHVILLGSTVNITC-----SL
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 QPRK--LHFYKNG--IKERFQITRINKTTARLWYKNF--LEPHASMY-CTAECPKHFQET
.::. .:. . . : .:. ::: .. .. : .... : : . .:
NP_001 KPRQGCFHYSRRNKLILYKFD-RRINFHHGHSLNSQVTGLPLGTTLFVCKLACINS-DEI
60 70 80 90 100 110
120 130 140 150 160
pF1KE2 LICGKDISSGYPPDIPDEVTCVIYEYSGNMTCTWNAGKLTYIDTKYVVHV---KSLETEE
::: .: : :. :....:. .:...:::. :. :.. :.:.... :.: ..
NP_001 QICGAEIFVGVAPEQPQNLSCIQKGEQGTVACTWERGRDTHLYTEYTLQLSGPKNLTWQK
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE2 EQQYLTSSY----INISTDSLQGGKKYLVWVQAANALGMEESKQLQIHLDDIVIPSAAVI
. . . .: ::.. .: .. .. . : :.:.:: : . . ::: :
NP_001 QCKDIYCDYLDFGINLTPESPES--NFTAKVTAVNSLGSSSSLPSTFTFLDIVRPLPPWD
180 190 200 210 220
230 240 250 260 270 280
pF1KE2 SRAETINATVPKTIIYWDSQTTIEKVSCEMRYKATTNQTWNVKEFDTNFTYVQ--QSEFY
: . .:.: . .:: .. . . ..::. .... ::. .: : .. .. .
NP_001 IRIKFQKASVSRCTLYWRDEGLV--LLNRLRYRPSNSRLWNM----VNVTKAKGRHDLLD
230 240 250 260 270 280
290 300 310 320 330 340
pF1KE2 LEPNIKYVFQVRCQ-ETGKRYWQPWSSPFFHKTPETVPQVTSKAFQHDTWNSGLTVASIS
:.: .: ::. . . : :. :: . .::: :
NP_001 LKPFTEYEFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHIDYSRQQISL
290 300 310 320 330 340
350 360 370 380 390 400
pF1KE2 TGHLTSDNRGDIGLLLGMIVFAVMLSILSLIGIFNRSFRTGIKRRILLLIPKWLYEDIPN
NP_001 FWKNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSK
350 360 370 380 390 400
>>NP_001306162 (OMIM: 601642) interleukin-12 receptor su (659 aa)
initn: 226 init1: 132 opt: 307 Z-score: 334.8 bits: 72.2 E(85289): 6.6e-12
Smith-Waterman score: 307; 23.5% identity (56.0% similar) in 327 aa overlap (12-320:10-321)
10 20 30 40 50
pF1KE2 MNQVTIQWDAVIALYILFSWCHGGITNINCS-GHIWVEPATIFKMGMNISIYCQAAIKNC
.:......: :. : . :.:. .. .: ...: : .
NP_001 MAHTFRGCSLAFMFIITWLLIKAKIDACKRGDVTVKPSHVILLGSTVNITC-----SL
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 QPRK--LHFYKNG--IKERFQITRINKTTARLWYKNF--LEPHASMY-CTAECPKHFQET
.::. .:. . . : .:. ::: .. .. : .... : : . .:
NP_001 KPRQGCFHYSRRNKLILYKFD-RRINFHHGHSLNSQVTGLPLGTTLFVCKLACINS-DEI
60 70 80 90 100 110
120 130 140 150 160
pF1KE2 LICGKDISSGYPPDIPDEVTCVIYEYSGNMTCTWNAGKLTYIDTKYVVHV---KSLETEE
::: .: : :. :....:. .:...:::. :. :.. :.:.... :.: ..
NP_001 QICGAEIFVGVAPEQPQNLSCIQKGEQGTVACTWERGRDTHLYTEYTLQLSGPKNLTWQK
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE2 EQQYLTSSY----INISTDSLQGGKKYLVWVQAANALGMEESKQLQIHLDDIVIPSAAVI
. . . .: ::.. .: .. .. . : :.:.:: : . . ::: :
NP_001 QCKDIYCDYLDFGINLTPESPES--NFTAKVTAVNSLGSSSSLPSTFTFLDIVRPLPPWD
180 190 200 210 220
230 240 250 260 270 280
pF1KE2 SRAETINATVPKTIIYWDSQTTIEKVSCEMRYKATTNQTWNVKEFDTNFTYVQ--QSEFY
: . .:.: . .:: .. . . ..::. .... ::. .: : .. .. .
NP_001 IRIKFQKASVSRCTLYWRDEGLV--LLNRLRYRPSNSRLWNM----VNVTKAKGRHDLLD
230 240 250 260 270 280
290 300 310 320 330 340
pF1KE2 LEPNIKYVFQVRCQ-ETGKRYWQPWSSPFFHKTPETVPQVTSKAFQHDTWNSGLTVASIS
:.: .: ::. . . : :. :: . .::: :
NP_001 LKPFTEYEFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHIDYSRQQISL
290 300 310 320 330 340
350 360 370 380 390 400
pF1KE2 TGHLTSDNRGDIGLLLGMIVFAVMLSILSLIGIFNRSFRTGIKRRILLLIPKWLYEDIPN
NP_001 FWKNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSK
350 360 370 380 390 400
>>XP_016856692 (OMIM: 601642) PREDICTED: interleukin-12 (659 aa)
initn: 226 init1: 132 opt: 307 Z-score: 334.8 bits: 72.2 E(85289): 6.6e-12
Smith-Waterman score: 307; 23.5% identity (56.0% similar) in 327 aa overlap (12-320:10-321)
10 20 30 40 50
pF1KE2 MNQVTIQWDAVIALYILFSWCHGGITNINCS-GHIWVEPATIFKMGMNISIYCQAAIKNC
.:......: :. : . :.:. .. .: ...: : .
XP_016 MAHTFRGCSLAFMFIITWLLIKAKIDACKRGDVTVKPSHVILLGSTVNITC-----SL
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 QPRK--LHFYKNG--IKERFQITRINKTTARLWYKNF--LEPHASMY-CTAECPKHFQET
.::. .:. . . : .:. ::: .. .. : .... : : . .:
XP_016 KPRQGCFHYSRRNKLILYKFD-RRINFHHGHSLNSQVTGLPLGTTLFVCKLACINS-DEI
60 70 80 90 100 110
120 130 140 150 160
pF1KE2 LICGKDISSGYPPDIPDEVTCVIYEYSGNMTCTWNAGKLTYIDTKYVVHV---KSLETEE
::: .: : :. :....:. .:...:::. :. :.. :.:.... :.: ..
XP_016 QICGAEIFVGVAPEQPQNLSCIQKGEQGTVACTWERGRDTHLYTEYTLQLSGPKNLTWQK
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE2 EQQYLTSSY----INISTDSLQGGKKYLVWVQAANALGMEESKQLQIHLDDIVIPSAAVI
. . . .: ::.. .: .. .. . : :.:.:: : . . ::: :
XP_016 QCKDIYCDYLDFGINLTPESPES--NFTAKVTAVNSLGSSSSLPSTFTFLDIVRPLPPWD
180 190 200 210 220
230 240 250 260 270 280
pF1KE2 SRAETINATVPKTIIYWDSQTTIEKVSCEMRYKATTNQTWNVKEFDTNFTYVQ--QSEFY
: . .:.: . .:: .. . . ..::. .... ::. .: : .. .. .
XP_016 IRIKFQKASVSRCTLYWRDEGLV--LLNRLRYRPSNSRLWNM----VNVTKAKGRHDLLD
230 240 250 260 270 280
290 300 310 320 330 340
pF1KE2 LEPNIKYVFQVRCQ-ETGKRYWQPWSSPFFHKTPETVPQVTSKAFQHDTWNSGLTVASIS
:.: .: ::. . . : :. :: . .::: :
XP_016 LKPFTEYEFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHIDYSRQQISL
290 300 310 320 330 340
350 360 370 380 390 400
pF1KE2 TGHLTSDNRGDIGLLLGMIVFAVMLSILSLIGIFNRSFRTGIKRRILLLIPKWLYEDIPN
XP_016 FWKNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSK
350 360 370 380 390 400
>>NP_001245143 (OMIM: 601642) interleukin-12 receptor su (659 aa)
initn: 226 init1: 132 opt: 307 Z-score: 334.8 bits: 72.2 E(85289): 6.6e-12
Smith-Waterman score: 307; 23.5% identity (56.0% similar) in 327 aa overlap (12-320:10-321)
10 20 30 40 50
pF1KE2 MNQVTIQWDAVIALYILFSWCHGGITNINCS-GHIWVEPATIFKMGMNISIYCQAAIKNC
.:......: :. : . :.:. .. .: ...: : .
NP_001 MAHTFRGCSLAFMFIITWLLIKAKIDACKRGDVTVKPSHVILLGSTVNITC-----SL
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 QPRK--LHFYKNG--IKERFQITRINKTTARLWYKNF--LEPHASMY-CTAECPKHFQET
.::. .:. . . : .:. ::: .. .. : .... : : . .:
NP_001 KPRQGCFHYSRRNKLILYKFD-RRINFHHGHSLNSQVTGLPLGTTLFVCKLACINS-DEI
60 70 80 90 100 110
120 130 140 150 160
pF1KE2 LICGKDISSGYPPDIPDEVTCVIYEYSGNMTCTWNAGKLTYIDTKYVVHV---KSLETEE
::: .: : :. :....:. .:...:::. :. :.. :.:.... :.: ..
NP_001 QICGAEIFVGVAPEQPQNLSCIQKGEQGTVACTWERGRDTHLYTEYTLQLSGPKNLTWQK
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE2 EQQYLTSSY----INISTDSLQGGKKYLVWVQAANALGMEESKQLQIHLDDIVIPSAAVI
. . . .: ::.. .: .. .. . : :.:.:: : . . ::: :
NP_001 QCKDIYCDYLDFGINLTPESPES--NFTAKVTAVNSLGSSSSLPSTFTFLDIVRPLPPWD
180 190 200 210 220
230 240 250 260 270 280
pF1KE2 SRAETINATVPKTIIYWDSQTTIEKVSCEMRYKATTNQTWNVKEFDTNFTYVQ--QSEFY
: . .:.: . .:: .. . . ..::. .... ::. .: : .. .. .
NP_001 IRIKFQKASVSRCTLYWRDEGLV--LLNRLRYRPSNSRLWNM----VNVTKAKGRHDLLD
230 240 250 260 270 280
290 300 310 320 330 340
pF1KE2 LEPNIKYVFQVRCQ-ETGKRYWQPWSSPFFHKTPETVPQVTSKAFQHDTWNSGLTVASIS
:.: .: ::. . . : :. :: . .::: :
NP_001 LKPFTEYEFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHIDYSRQQISL
290 300 310 320 330 340
350 360 370 380 390 400
pF1KE2 TGHLTSDNRGDIGLLLGMIVFAVMLSILSLIGIFNRSFRTGIKRRILLLIPKWLYEDIPN
NP_001 FWKNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSK
350 360 370 380 390 400
>>XP_016856691 (OMIM: 601642) PREDICTED: interleukin-12 (700 aa)
initn: 226 init1: 132 opt: 307 Z-score: 334.4 bits: 72.2 E(85289): 6.9e-12
Smith-Waterman score: 307; 23.5% identity (56.0% similar) in 327 aa overlap (12-320:10-321)
10 20 30 40 50
pF1KE2 MNQVTIQWDAVIALYILFSWCHGGITNINCS-GHIWVEPATIFKMGMNISIYCQAAIKNC
.:......: :. : . :.:. .. .: ...: : .
XP_016 MAHTFRGCSLAFMFIITWLLIKAKIDACKRGDVTVKPSHVILLGSTVNITC-----SL
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 QPRK--LHFYKNG--IKERFQITRINKTTARLWYKNF--LEPHASMY-CTAECPKHFQET
.::. .:. . . : .:. ::: .. .. : .... : : . .:
XP_016 KPRQGCFHYSRRNKLILYKFD-RRINFHHGHSLNSQVTGLPLGTTLFVCKLACINS-DEI
60 70 80 90 100 110
120 130 140 150 160
pF1KE2 LICGKDISSGYPPDIPDEVTCVIYEYSGNMTCTWNAGKLTYIDTKYVVHV---KSLETEE
::: .: : :. :....:. .:...:::. :. :.. :.:.... :.: ..
XP_016 QICGAEIFVGVAPEQPQNLSCIQKGEQGTVACTWERGRDTHLYTEYTLQLSGPKNLTWQK
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE2 EQQYLTSSY----INISTDSLQGGKKYLVWVQAANALGMEESKQLQIHLDDIVIPSAAVI
. . . .: ::.. .: .. .. . : :.:.:: : . . ::: :
XP_016 QCKDIYCDYLDFGINLTPESPES--NFTAKVTAVNSLGSSSSLPSTFTFLDIVRPLPPWD
180 190 200 210 220
230 240 250 260 270 280
pF1KE2 SRAETINATVPKTIIYWDSQTTIEKVSCEMRYKATTNQTWNVKEFDTNFTYVQ--QSEFY
: . .:.: . .:: .. . . ..::. .... ::. .: : .. .. .
XP_016 IRIKFQKASVSRCTLYWRDEGLV--LLNRLRYRPSNSRLWNM----VNVTKAKGRHDLLD
230 240 250 260 270 280
290 300 310 320 330 340
pF1KE2 LEPNIKYVFQVRCQ-ETGKRYWQPWSSPFFHKTPETVPQVTSKAFQHDTWNSGLTVASIS
:.: .: ::. . . : :. :: . .::: :
XP_016 LKPFTEYEFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHIDYSRQQISL
290 300 310 320 330 340
350 360 370 380 390 400
pF1KE2 TGHLTSDNRGDIGLLLGMIVFAVMLSILSLIGIFNRSFRTGIKRRILLLIPKWLYEDIPN
XP_016 FWKNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSK
350 360 370 380 390 400
629 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 19:17:04 2016 done: Sun Nov 6 19:17:06 2016
Total Scan time: 10.440 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]