Result of FASTA (omim) for
pFN21AE2021
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2021, 599 aa
1>>>pF1KE2021 599 - 599 aa - 599 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.1016+/-0.00043; mu= 10.0585+/- 0.027
mean_var=108.0159+/-21.931, 0's: 0 Z-trim(112.7): 50 B-trim: 0 in 0/54
Lambda= 0.123404
statistics sampled from 21638 (21673) to 21638 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.615), E-opt: 0.2 (0.254), width: 16
Scan time: 7.860
The best scores are: opt bits E(85289)
NP_057322 (OMIM: 606949) anaphase-promoting comple ( 599) 3884 702.9 7.9e-202
XP_011536756 (OMIM: 606949) PREDICTED: anaphase-pr ( 579) 3453 626.1 9.7e-179
NP_001131136 (OMIM: 606949) anaphase-promoting com ( 537) 3452 625.9 1e-178
XP_016874915 (OMIM: 606949) PREDICTED: anaphase-pr ( 498) 3231 586.6 6.7e-167
XP_016874916 (OMIM: 606949) PREDICTED: anaphase-pr ( 498) 3231 586.6 6.7e-167
XP_016874914 (OMIM: 606949) PREDICTED: anaphase-pr ( 524) 2683 489.0 1.6e-137
XP_005253960 (OMIM: 606949) PREDICTED: anaphase-pr ( 378) 2472 451.4 2.5e-126
XP_016874917 (OMIM: 606949) PREDICTED: anaphase-pr ( 378) 2472 451.4 2.5e-126
XP_016880977 (OMIM: 116946) PREDICTED: cell divisi ( 427) 259 57.4 1.1e-07
XP_016880974 (OMIM: 116946) PREDICTED: cell divisi ( 721) 259 57.5 1.8e-07
XP_011523852 (OMIM: 116946) PREDICTED: cell divisi ( 727) 259 57.5 1.8e-07
NP_001280020 (OMIM: 116946) cell division cycle pr ( 763) 259 57.5 1.9e-07
XP_011523851 (OMIM: 116946) PREDICTED: cell divisi ( 769) 259 57.5 1.9e-07
XP_011523850 (OMIM: 116946) PREDICTED: cell divisi ( 769) 259 57.5 1.9e-07
NP_001247 (OMIM: 116946) cell division cycle prote ( 824) 259 57.6 2e-07
NP_001107563 (OMIM: 116946) cell division cycle pr ( 830) 259 57.6 2e-07
XP_016880975 (OMIM: 116946) PREDICTED: cell divisi ( 720) 252 56.3 4.2e-07
XP_016880973 (OMIM: 116946) PREDICTED: cell divisi ( 762) 252 56.3 4.4e-07
NP_001280018 (OMIM: 116946) cell division cycle pr ( 823) 252 56.3 4.7e-07
XP_011523848 (OMIM: 116946) PREDICTED: cell divisi ( 829) 252 56.3 4.7e-07
XP_016875496 (OMIM: 615855) PREDICTED: transmembra ( 618) 225 51.4 1e-05
NP_787057 (OMIM: 615855) transmembrane and TPR rep ( 774) 225 51.5 1.3e-05
XP_016875494 (OMIM: 615855) PREDICTED: transmembra ( 813) 225 51.5 1.3e-05
XP_016875493 (OMIM: 615855) PREDICTED: transmembra ( 875) 225 51.5 1.4e-05
NP_001180380 (OMIM: 615855) transmembrane and TPR ( 882) 225 51.5 1.4e-05
XP_016875492 (OMIM: 615855) PREDICTED: transmembra ( 888) 225 51.5 1.4e-05
XP_005253556 (OMIM: 615855) PREDICTED: transmembra ( 944) 225 51.5 1.5e-05
XP_016880976 (OMIM: 116946) PREDICTED: cell divisi ( 708) 205 47.9 0.00014
XP_016880971 (OMIM: 116946) PREDICTED: cell divisi ( 769) 205 47.9 0.00015
XP_011523849 (OMIM: 116946) PREDICTED: cell divisi ( 775) 205 47.9 0.00015
XP_016880972 (OMIM: 116946) PREDICTED: cell divisi ( 768) 198 46.7 0.00035
XP_016880970 (OMIM: 116946) PREDICTED: cell divisi ( 774) 198 46.7 0.00035
NP_858059 (OMIM: 300255) UDP-N-acetylglucosamine-- (1036) 181 43.7 0.0037
NP_858058 (OMIM: 300255) UDP-N-acetylglucosamine-- (1046) 181 43.7 0.0037
>>NP_057322 (OMIM: 606949) anaphase-promoting complex su (599 aa)
initn: 3884 init1: 3884 opt: 3884 Z-score: 3744.4 bits: 702.9 E(85289): 7.9e-202
Smith-Waterman score: 3884; 100.0% identity (100.0% similar) in 599 aa overlap (1-599:1-599)
10 20 30 40 50 60
pF1KE2 MDPGDAAILESSLRILYRLFESVLPPLPAALQSRMNVIDHVRDMAAAGLHSNVRLLSSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MDPGDAAILESSLRILYRLFESVLPPLPAALQSRMNVIDHVRDMAAAGLHSNVRLLSSLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LTMSNNNPELFSPPQKYQLLVYHADSLFHDKEYRNAVSKYTMALQQKKALSKTSKVRPST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 LTMSNNNPELFSPPQKYQLLVYHADSLFHDKEYRNAVSKYTMALQQKKALSKTSKVRPST
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 GNSASTPQSQCLPSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQRTPKINMMLANLYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 GNSASTPQSQCLPSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQRTPKINMMLANLYK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 KAGQERPSVTSYKEVLRQCPLALDAILGLLSLSVKGAEVASMTMNVIQTVPNLDWLSVWI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 KAGQERPSVTSYKEVLRQCPLALDAILGLLSLSVKGAEVASMTMNVIQTVPNLDWLSVWI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 KAYAFVHTGDNSRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 KAYAFVHTGDNSRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQML
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 DPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 DPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 LGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 LGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLAS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 NSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 NSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 KKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 KKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDP
490 500 510 520 530 540
550 560 570 580 590
pF1KE2 NDQKSLEGMQKMEKEESPTDATQEEDVDDMEGSGEEGDLEGSDSEAAQWADQEQWFGMQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 NDQKSLEGMQKMEKEESPTDATQEEDVDDMEGSGEEGDLEGSDSEAAQWADQEQWFGMQ
550 560 570 580 590
>>XP_011536756 (OMIM: 606949) PREDICTED: anaphase-promot (579 aa)
initn: 3453 init1: 3453 opt: 3453 Z-score: 3329.9 bits: 626.1 E(85289): 9.7e-179
Smith-Waterman score: 3453; 100.0% identity (100.0% similar) in 531 aa overlap (69-599:49-579)
40 50 60 70 80 90
pF1KE2 DHVRDMAAAGLHSNVRLLSSLLLTMSNNNPELFSPPQKYQLLVYHADSLFHDKEYRNAVS
::::::::::::::::::::::::::::::
XP_011 TVLISALPPPSGFSLDISPKEPSLTPRTLGELFSPPQKYQLLVYHADSLFHDKEYRNAVS
20 30 40 50 60 70
100 110 120 130 140 150
pF1KE2 KYTMALQQKKALSKTSKVRPSTGNSASTPQSQCLPSEIEVKYKMAECYTMLKQDKDAIAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KYTMALQQKKALSKTSKVRPSTGNSASTPQSQCLPSEIEVKYKMAECYTMLKQDKDAIAI
80 90 100 110 120 130
160 170 180 190 200 210
pF1KE2 LDGIPSRQRTPKINMMLANLYKKAGQERPSVTSYKEVLRQCPLALDAILGLLSLSVKGAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDGIPSRQRTPKINMMLANLYKKAGQERPSVTSYKEVLRQCPLALDAILGLLSLSVKGAE
140 150 160 170 180 190
220 230 240 250 260 270
pF1KE2 VASMTMNVIQTVPNLDWLSVWIKAYAFVHTGDNSRAISTICSLEKKSLLRDNVDLLGSLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VASMTMNVIQTVPNLDWLSVWIKAYAFVHTGDNSRAISTICSLEKKSLLRDNVDLLGSLA
200 210 220 230 240 250
280 290 300 310 320 330
pF1KE2 DLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQH
260 270 280 290 300 310
340 350 360 370 380 390
pF1KE2 AEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFRE
320 330 340 350 360 370
400 410 420 430 440 450
pF1KE2 AIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQ
380 390 400 410 420 430
460 470 480 490 500 510
pF1KE2 EKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDF
440 450 460 470 480 490
520 530 540 550 560 570
pF1KE2 LVAVNEYQEAMDQYSIALSLDPNDQKSLEGMQKMEKEESPTDATQEEDVDDMEGSGEEGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVAVNEYQEAMDQYSIALSLDPNDQKSLEGMQKMEKEESPTDATQEEDVDDMEGSGEEGD
500 510 520 530 540 550
580 590
pF1KE2 LEGSDSEAAQWADQEQWFGMQ
:::::::::::::::::::::
XP_011 LEGSDSEAAQWADQEQWFGMQ
560 570
>>NP_001131136 (OMIM: 606949) anaphase-promoting complex (537 aa)
initn: 3452 init1: 3452 opt: 3452 Z-score: 3329.5 bits: 625.9 E(85289): 1e-178
Smith-Waterman score: 3452; 100.0% identity (100.0% similar) in 536 aa overlap (1-536:1-536)
10 20 30 40 50 60
pF1KE2 MDPGDAAILESSLRILYRLFESVLPPLPAALQSRMNVIDHVRDMAAAGLHSNVRLLSSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDPGDAAILESSLRILYRLFESVLPPLPAALQSRMNVIDHVRDMAAAGLHSNVRLLSSLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LTMSNNNPELFSPPQKYQLLVYHADSLFHDKEYRNAVSKYTMALQQKKALSKTSKVRPST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTMSNNNPELFSPPQKYQLLVYHADSLFHDKEYRNAVSKYTMALQQKKALSKTSKVRPST
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 GNSASTPQSQCLPSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQRTPKINMMLANLYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNSASTPQSQCLPSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQRTPKINMMLANLYK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 KAGQERPSVTSYKEVLRQCPLALDAILGLLSLSVKGAEVASMTMNVIQTVPNLDWLSVWI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAGQERPSVTSYKEVLRQCPLALDAILGLLSLSVKGAEVASMTMNVIQTVPNLDWLSVWI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 KAYAFVHTGDNSRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAYAFVHTGDNSRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQML
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 DPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 LGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLAS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 NSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 KKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALR
490 500 510 520 530
550 560 570 580 590
pF1KE2 NDQKSLEGMQKMEKEESPTDATQEEDVDDMEGSGEEGDLEGSDSEAAQWADQEQWFGMQ
>>XP_016874915 (OMIM: 606949) PREDICTED: anaphase-promot (498 aa)
initn: 3231 init1: 3231 opt: 3231 Z-score: 3117.4 bits: 586.6 E(85289): 6.7e-167
Smith-Waterman score: 3231; 100.0% identity (100.0% similar) in 498 aa overlap (102-599:1-498)
80 90 100 110 120 130
pF1KE2 SPPQKYQLLVYHADSLFHDKEYRNAVSKYTMALQQKKALSKTSKVRPSTGNSASTPQSQC
::::::::::::::::::::::::::::::
XP_016 MALQQKKALSKTSKVRPSTGNSASTPQSQC
10 20 30
140 150 160 170 180 190
pF1KE2 LPSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQRTPKINMMLANLYKKAGQERPSVTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQRTPKINMMLANLYKKAGQERPSVTS
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE2 YKEVLRQCPLALDAILGLLSLSVKGAEVASMTMNVIQTVPNLDWLSVWIKAYAFVHTGDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKEVLRQCPLALDAILGLLSLSVKGAEVASMTMNVIQTVPNLDWLSVWIKAYAFVHTGDN
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE2 SRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVY
160 170 180 190 200 210
320 330 340 350 360 370
pF1KE2 GYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSN
220 230 240 250 260 270
380 390 400 410 420 430
pF1KE2 SVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMAN
280 290 300 310 320 330
440 450 460 470 480 490
pF1KE2 NVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVVKKAELLSREQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVVKKAELLSREQK
340 350 360 370 380 390
500 510 520 530 540 550
pF1KE2 YEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDPNDQKSLEGMQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDPNDQKSLEGMQK
400 410 420 430 440 450
560 570 580 590
pF1KE2 MEKEESPTDATQEEDVDDMEGSGEEGDLEGSDSEAAQWADQEQWFGMQ
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEKEESPTDATQEEDVDDMEGSGEEGDLEGSDSEAAQWADQEQWFGMQ
460 470 480 490
>>XP_016874916 (OMIM: 606949) PREDICTED: anaphase-promot (498 aa)
initn: 3231 init1: 3231 opt: 3231 Z-score: 3117.4 bits: 586.6 E(85289): 6.7e-167
Smith-Waterman score: 3231; 100.0% identity (100.0% similar) in 498 aa overlap (102-599:1-498)
80 90 100 110 120 130
pF1KE2 SPPQKYQLLVYHADSLFHDKEYRNAVSKYTMALQQKKALSKTSKVRPSTGNSASTPQSQC
::::::::::::::::::::::::::::::
XP_016 MALQQKKALSKTSKVRPSTGNSASTPQSQC
10 20 30
140 150 160 170 180 190
pF1KE2 LPSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQRTPKINMMLANLYKKAGQERPSVTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQRTPKINMMLANLYKKAGQERPSVTS
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE2 YKEVLRQCPLALDAILGLLSLSVKGAEVASMTMNVIQTVPNLDWLSVWIKAYAFVHTGDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKEVLRQCPLALDAILGLLSLSVKGAEVASMTMNVIQTVPNLDWLSVWIKAYAFVHTGDN
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE2 SRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVY
160 170 180 190 200 210
320 330 340 350 360 370
pF1KE2 GYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSN
220 230 240 250 260 270
380 390 400 410 420 430
pF1KE2 SVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMAN
280 290 300 310 320 330
440 450 460 470 480 490
pF1KE2 NVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVVKKAELLSREQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVVKKAELLSREQK
340 350 360 370 380 390
500 510 520 530 540 550
pF1KE2 YEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDPNDQKSLEGMQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDPNDQKSLEGMQK
400 410 420 430 440 450
560 570 580 590
pF1KE2 MEKEESPTDATQEEDVDDMEGSGEEGDLEGSDSEAAQWADQEQWFGMQ
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEKEESPTDATQEEDVDDMEGSGEEGDLEGSDSEAAQWADQEQWFGMQ
460 470 480 490
>>XP_016874914 (OMIM: 606949) PREDICTED: anaphase-promot (524 aa)
initn: 3414 init1: 2681 opt: 2683 Z-score: 2589.7 bits: 489.0 E(85289): 1.6e-137
Smith-Waterman score: 3268; 87.5% identity (87.5% similar) in 599 aa overlap (1-599:1-524)
10 20 30 40 50 60
pF1KE2 MDPGDAAILESSLRILYRLFESVLPPLPAALQSRMNVIDHVRDMAAAGLHSNVRLLSSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDPGDAAILESSLRILYRLFESVLPPLPAALQSRMNVIDHVRDMAAAGLHSNVRLLSSLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LTMSNNNPELFSPPQKYQLLVYHADSLFHDKEYRNAVSKYTMALQQKKALSKTSKVRPST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTMSNNNPELFSPPQKYQLLVYHADSLFHDKEYRNAVSKYTMALQQKKALSKTSKVRPST
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 GNSASTPQSQCLPSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQRTPKINMMLANLYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNSASTPQSQCLPSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQRTPKINMMLANLYK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 KAGQERPSVTSYKEVLRQCPLALDAILGLLSLSVKGAEVASMTMNVIQTVPNLDWLSVWI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAGQERPSVTSYKEVLRQCPLALDAILGLLSLSVKGAEVASMTMNVIQTVPNLDWLSVWI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 KAYAFVHTGDNSRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAYAFVHTGDNSRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQML
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 DPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 LGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEG--------
370 380 390 400 410
430 440 450 460 470 480
pF1KE2 NSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVV
XP_016 ------------------------------------------------------------
490 500 510 520 530 540
pF1KE2 KKAELLSREQKYEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDP
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 -------REQKYEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDP
420 430 440 450 460
550 560 570 580 590
pF1KE2 NDQKSLEGMQKMEKEESPTDATQEEDVDDMEGSGEEGDLEGSDSEAAQWADQEQWFGMQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NDQKSLEGMQKMEKEESPTDATQEEDVDDMEGSGEEGDLEGSDSEAAQWADQEQWFGMQ
470 480 490 500 510 520
>>XP_005253960 (OMIM: 606949) PREDICTED: anaphase-promot (378 aa)
initn: 2472 init1: 2472 opt: 2472 Z-score: 2389.0 bits: 451.4 E(85289): 2.5e-126
Smith-Waterman score: 2472; 100.0% identity (100.0% similar) in 378 aa overlap (222-599:1-378)
200 210 220 230 240 250
pF1KE2 YKEVLRQCPLALDAILGLLSLSVKGAEVASMTMNVIQTVPNLDWLSVWIKAYAFVHTGDN
::::::::::::::::::::::::::::::
XP_005 MTMNVIQTVPNLDWLSVWIKAYAFVHTGDN
10 20 30
260 270 280 290 300 310
pF1KE2 SRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVY
40 50 60 70 80 90
320 330 340 350 360 370
pF1KE2 GYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSN
100 110 120 130 140 150
380 390 400 410 420 430
pF1KE2 SVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMAN
160 170 180 190 200 210
440 450 460 470 480 490
pF1KE2 NVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVVKKAELLSREQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVVKKAELLSREQK
220 230 240 250 260 270
500 510 520 530 540 550
pF1KE2 YEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDPNDQKSLEGMQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDPNDQKSLEGMQK
280 290 300 310 320 330
560 570 580 590
pF1KE2 MEKEESPTDATQEEDVDDMEGSGEEGDLEGSDSEAAQWADQEQWFGMQ
::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEKEESPTDATQEEDVDDMEGSGEEGDLEGSDSEAAQWADQEQWFGMQ
340 350 360 370
>>XP_016874917 (OMIM: 606949) PREDICTED: anaphase-promot (378 aa)
initn: 2472 init1: 2472 opt: 2472 Z-score: 2389.0 bits: 451.4 E(85289): 2.5e-126
Smith-Waterman score: 2472; 100.0% identity (100.0% similar) in 378 aa overlap (222-599:1-378)
200 210 220 230 240 250
pF1KE2 YKEVLRQCPLALDAILGLLSLSVKGAEVASMTMNVIQTVPNLDWLSVWIKAYAFVHTGDN
::::::::::::::::::::::::::::::
XP_016 MTMNVIQTVPNLDWLSVWIKAYAFVHTGDN
10 20 30
260 270 280 290 300 310
pF1KE2 SRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVY
40 50 60 70 80 90
320 330 340 350 360 370
pF1KE2 GYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSN
100 110 120 130 140 150
380 390 400 410 420 430
pF1KE2 SVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMAN
160 170 180 190 200 210
440 450 460 470 480 490
pF1KE2 NVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVVKKAELLSREQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVVKKAELLSREQK
220 230 240 250 260 270
500 510 520 530 540 550
pF1KE2 YEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDPNDQKSLEGMQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YEDGIALLRNALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDPNDQKSLEGMQK
280 290 300 310 320 330
560 570 580 590
pF1KE2 MEKEESPTDATQEEDVDDMEGSGEEGDLEGSDSEAAQWADQEQWFGMQ
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEKEESPTDATQEEDVDDMEGSGEEGDLEGSDSEAAQWADQEQWFGMQ
340 350 360 370
>>XP_016880977 (OMIM: 116946) PREDICTED: cell division c (427 aa)
initn: 82 init1: 82 opt: 259 Z-score: 258.8 bits: 57.4 E(85289): 1.1e-07
Smith-Waterman score: 261; 20.8% identity (55.1% similar) in 432 aa overlap (162-585:7-418)
140 150 160 170 180 190
pF1KE2 LPSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQRTPKINMMLANLYKKAGQERPSVTS
::.:. : : :.: .:....
XP_016 MKFPPKIPNRKTKSKTN--------KGGITQPNIND
10 20
200 210 220 230 240 250
pF1KE2 YKEVLRQCPLALDA-ILGLLSLSVKGAEVASMTMNVIQTVPNLDWLSVWIKAYAFVHTGD
:. . ::. :.. ..:. .. ..... . .. : :.: . . .
XP_016 SLEITK-----LDSSIISEGKISTITPQIQAFNLQKAAAEGLMSLLREMGKGYLALCSYN
30 40 50 60 70 80
260 270 280 290 300 310
pF1KE2 NSRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDV
..::. . : .. : : ... ::. .. .. : ... .. : ..::..
XP_016 CKEAINILSHLPSHHYNTGWV--LCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEI
90 100 110 120 130 140
320 330 340 350 360
pF1KE2 YGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSG-CHSFYSKRYSRALYLGAKAIQLN
:. : . . . :. : ... . : : ..: : :. ..... :. . .:::..
XP_016 YSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSL-QREHDIAIKFFQRAIQVD
150 160 170 180 190 200
370 380 390 400 410 420
pF1KE2 SNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVM
: . : : : . ....:. ::.:::. : . . . :: : .... : .
XP_016 PNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEM-
210 220 230 240 250
430 440 450 460 470 480
pF1KE2 ANNVYKTLGANAQTLTLLATVCLEDPVTQ--EKAKTLLDKALTQRPDYIKAVVKKAELLS
. :.: : :. .:: . . . . . ::: :.::.. : ..: .:
XP_016 --HFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLF
260 270 280 290 300 310
490 500 510 520 530 540
pF1KE2 REQKYEDGIALLRN-ALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDPNDQKSL
..::.... :.. .. ... ..: ... . :. ..: :..:::. ..
XP_016 ANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANN-
320 330 340 350 360 370
550 560 570 580 590
pF1KE2 EGMQKMEKEESPTDA---TQEEDVDDMEGSGEEGDLEGSDSEAAQWADQEQWFGMQ
. . ..:. : : ::::.. . : : . ...:..
XP_016 QIKEAIDKRYLPDDEEPITQEEQIMGTDESQESSMTDADDTQLHAAESDEF
380 390 400 410 420
>>XP_016880974 (OMIM: 116946) PREDICTED: cell division c (721 aa)
initn: 82 init1: 82 opt: 259 Z-score: 255.2 bits: 57.5 E(85289): 1.8e-07
Smith-Waterman score: 268; 20.1% identity (53.5% similar) in 493 aa overlap (101-585:240-712)
80 90 100 110 120 130
pF1KE2 FSPPQKYQLLVYHADSLFHDKEYRNAVSKYTMALQQKKALSKTSKVRPSTGNSASTPQSQ
: : : .. . ... :.. . . : .
XP_016 TGAPSKKSVARIGQTGTKSVFSQSGNSREVTPILAQTQSSGPQTSTTPQVLSPTITSPPN
210 220 230 240 250 260
140 150 160 170 180 190
pF1KE2 CLPSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQRTPKINMMLANLYKKAGQERPSVT
:: . . : .. : . . ::.:. : : :.: .:...
XP_016 ALPRRSSRLFTSDSSTTKENSKKLKMKFPPKIPNRKTKSKTN--------KGGITQPNIN
270 280 290 300 310 320
200 210 220 230 240
pF1KE2 SYKEVLRQCPLALDA-ILGLLSLSVKGAEVASMTMNVIQTVPNLDWLSVWIKAYAFVHTG
. :. . ::. :.. ..:. .. ..... . .. : :.: . .
XP_016 DSLEITK-----LDSSIISEGKISTITPQIQAFNLQKAAAEGLMSLLREMGKGYLALCSY
330 340 350 360 370
250 260 270 280 290 300
pF1KE2 DNSRAISTICSLEKKSLLRDNVDLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMD
. ..::. . : .. : : ... ::. .. .. : ... .. : ..::.
XP_016 NCKEAINILSHLPSHHYNTGWV--LCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGME
380 390 400 410 420 430
310 320 330 340 350 360
pF1KE2 VYGYLLAREGRLEDVENLGCRLFNISDQHAEPWVVSG-CHSFYSKRYSRALYLGAKAIQL
.:. : . . . :. : ... . : : ..: : :. ..... :. . .:::.
XP_016 IYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSL-QREHDIAIKFFQRAIQV
440 450 460 470 480 490
370 380 390 400 410 420
pF1KE2 NSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMV
. : . : : : . ....:. ::.:::. : . . . :: : .... : .
XP_016 DPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEM
500 510 520 530 540 550
430 440 450 460 470 480
pF1KE2 MANNVYKTLGANAQTLTLLATVCLEDPVTQ--EKAKTLLDKALTQRPDYIKAVVKKAELL
. :.: : :. .:: . . . . . ::: :.::.. : ..: .:
XP_016 ---HFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVL
560 570 580 590 600 610
490 500 510 520 530 540
pF1KE2 SREQKYEDGIALLRN-ALANQSDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDPNDQKS
..::.... :.. .. ... ..: ... . :. ..: :..:::. ..
XP_016 FANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANN
620 630 640 650 660 670
550 560 570 580 590
pF1KE2 LEGMQKMEKEESPTDA---TQEEDVDDMEGSGEEGDLEGSDSEAAQWADQEQWFGMQ
. . ..:. : : ::::.. . : : . ...:..
XP_016 -QIKEAIDKRYLPDDEEPITQEEQIMGTDESQESSMTDADDTQLHAAESDEF
680 690 700 710 720
599 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 16:07:09 2016 done: Mon Nov 7 16:07:10 2016
Total Scan time: 7.860 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]